Innate sensing of oxidation-specific epitopes in health and disease
Open accessAbstract
Ageing, infections and inflammation result in oxidative stress that can irreversibly damage cellular structures. The oxidative damage of lipids in membranes or lipoproteins is one of these deleterious consequences that not only alters lipid function but also leads to the formation of neo-self epitopes - oxidation-specific epitopes (OSEs) - which are present on dying cells and damaged proteins. OSEs represent endogenous damage-associated molecular patterns that are recognized by pattern recognition receptors and the proteins of the innate immune system, and thereby enable the host to sense and remove dangerous biological waste and to maintain homeostasis. If this system is dysfunctional or overwhelmed, the accumulation of OSEs can trigger chronic inflammation and the development of diseases, such as atherosclerosis and age-related macular degeneration. Understanding the molecular components and mechanisms that are involved in this process will help to identify individuals with an increased risk of developing chronic inflammation, and will also help to indicate novel modes of therapeutic intervention.
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Integrity signals
Registry
Cites
Statistics
Claims the paper makes
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Claims other papers make about this one
Each is checked against this paper’s own text: does it say what the citing paper says it does?
The oxidation of lipids induces degradation products through lipid peroxidation, generating 4-HNE and MDA, which can modify protein function.
“The oxidation of lipids induces degradation products through a process known as lipid peroxidation. This results in the generation of highly reactive products such as reactive aldehydes 4-hydroxynonenal (4-HNE) and malondialdehyde (MDA), which can modify protein function (Binder et al., 2016).”
From Small Extracellular Vesicles Have GST Activity and Ameliorate Senescence-Related Tissue Damage (2020) · cites this paper as Binder et al., 2016
Self-check
Percentages, sums and reported differences re-computed from the paper’s own numbers.
The self-check needs the paper’s full text.
Cites
Oxidants, oxidative stress and the biology of ageing
Finkel, T., & Holbrook, N. J. (2000) · Nature · doi:10.1038/35041687 · Cited by 9,413 · see citing works
ROS function in redox signaling and oxidative stress
Schieber, M., & Chandel, N. S. (2014) · Current Biology · doi:10.1016/j.cub.2014.03.034 · Cited by 6,931 · see citing works
Chemistry and biochemistry of 4-hydroxynonenal, malonaldehyde and related aldehydes
Esterbauer, H., Schaur, R. J., & Zollner, H. (1991) · Free Radical Biology and Medicine · doi:10.1016/0891-5849(91)90192-6 · Cited by 6,672 · see citing works
NLRP3 inflammasomes are required for atherogenesis and activated by cholesterol crystals
Duewell, P., Kono, H., Rayner, K. J., Sirois, C. M., Vladimer, G., Bauernfeind, F. G., Abela, G. S., Franchi, L., Nuñez, G., Schnurr, M., et al. (2010) · Nature · doi:10.1038/nature08938 · Cited by 4,026 · see citing works
Sterile inflammation: sensing and reacting to damage
Chen, G. Y., & Nuñez, G. (2010) · Nature Reviews Immunology · doi:10.1038/nri2873 · Cited by 3,051 · see citing works
Pro-resolving lipid mediators are leads for resolution physiology
Serhan, C. N. (2014) · Nature · doi:10.1038/nature13479 · Cited by 3,041 · see citing works
Activation and regulation of the inflammasomes
Latz, E., Xiao, T. S., & Stutz, A. (2013) · Nature Reviews Immunology · doi:10.1038/nri3452 · Cited by 2,884 · see citing works
Macrophages in atherosclerosis: a dynamic balance
Moore, K. J., Sheedy, F. J., & Fisher, E. A. (2013) · Nature reviews. Immunology · doi:10.1038/nri3520 · Cited by 2,559 · see citing works
Complement factor H polymorphism and age-related macular degeneration
Edwards, A. O., Ritter, R., Abel, K. J., Manning, A., Panhuysen, C., & Farrer, L. A. (2005) · Science · doi:10.1126/science.1110189 · Cited by 2,449 · see citing works
Complement factor H variant increases the risk of age-related macular degeneration
Haines, J. L., Hauser, M. A., Schmidt, S., Scott, W. K., Olson, L. M., Gallins, P., Spencer, K. L., Kwan, S. Y., Noureddine, M., Gilbert, J. R., et al. (2005) · Science · doi:10.1126/science.1110359 · Cited by 2,424 · see citing works
Myeloperoxidase: friend and foe
Klebanoff, S. J. (2005) · Journal of Leukocyte Biology · doi:10.1189/jlb.1204697 · Cited by 2,282 · see citing works
Ylä‐Herttuala, S., Palinski, W., Rosenfeld, M. E., Parthasarathy, S., Carew, T. E., Butler, S. S., Witztum, J. L., & Steinberg, D. H. (1989) · Journal of Clinical Investigation · doi:10.1172/jci114271 · Cited by 1,877 · see citing works
Self-citationBeyond oxidative stress: an immunologist's guide to reactive oxygen species
Nathan, C., & Cunningham-Bussel, A. (2013) · Nature Reviews Immunology · doi:10.1038/nri3423 · Cited by 1,619 · see citing works
Stewart, C. R., Stuart, L. M., Wilkinson, K., van Gils, J. M., Deng, J., Halle, A., Rayner, K. J., Boyer, L., Zhong, R., Frazier, W. A., et al. (2010) · Nature Immunology · doi:10.1038/ni.1836 · Cited by 1,513 · see citing works
Imai, Y., Kuba, K., Neely, G. G., Yaghubian-Malhami, R., Perkmann, T., van Loo, G., Ermolaeva, M., Veldhuizen, R., Leung, Y. H. C., Wang, H., et al. (2008) · Cell · doi:10.1016/j.cell.2008.02.043 · Cited by 1,356 · see citing works
Self-citationComplement regulators and inhibitory proteins
Zipfel, P. F., & Skerka, C. (2009) · Nature reviews. Immunology · doi:10.1038/nri2620 · Cited by 1,268 · see citing works
Apoptotic cell clearance: basic biology and therapeutic potential
Poon, I. K. H., Lucas, C. D., Rossi, A. G., & Ravichandran, K. S. (2014) · Nature Reviews Immunology · doi:10.1038/nri3607 · Cited by 1,223 · see citing works
Danger signals: SOS to the immune system
Gallucci, S., & Matzinger, P. (2001) · Current Opinion in Immunology · doi:10.1016/s0952-7915(00)00191-6 · Cited by 1,204 · see citing works
Macrophage death and defective inflammation resolution in atherosclerosis
Tabas, I. (2010) · Nature Reviews Immunology · doi:10.1038/nri2675 · Cited by 1,120 · see citing works
Kunjathoor, V., Febbraio, M., Podrez, E., Moore, K., Andersson, L., Koehn, S. L., Rhee, J. S., Silverstein, R., Hoff, H., & Freeman, M. (2002) · Journal of Biological Chemistry · doi:10.1074/jbc.m209649200 · Cited by 1,064 · see citing works
Toll-like Receptor 4 Polymorphisms and Atherogenesis
Kiechl, S. J., Lorenz, E., Reindl, M., Wiedermann, C. J., Oberhollenzer, F., Bonora, E., Willeit, J., & Schwartz, D. A. (2002) · New England Journal of Medicine · doi:10.1056/nejmoa012673 · Cited by 1,024 · see citing works
Michelsen, K. S., Wong, M. H., Shah, P. K., Zhang, W., Yano, J., Doherty, T. M., Akira, S., Rajavashisth, T. B., & Arditi, M. (2004) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0403249101 · Cited by 1,019 · see citing works
Phagocytosis of apoptotic cells in homeostasis
Arandjelovic, S., & Ravichandran, K. S. (2015) · Nature Immunology · doi:10.1038/ni.3253 · Cited by 959 · see citing works
Sheedy, F. J., Grebe, A., Rayner, K. J., Kalantari, P., Ramkhelawon, B., Carpenter, S. B., Becker, C. E., Ediriweera, H. N., Mullick, A. E., Golenbock, D. T., et al. (2013) · Nature Immunology · doi:10.1038/ni.2639 · Cited by 935 · see citing works
Human C-reactive protein: expression, structure, and function
Volanakis, J. E. (2001) · Molecular Immunology · doi:10.1016/s0161-5890(01)00042-6 · Cited by 928 · see citing works
Savina, A., Jancic, C. C., Hugues, S., Guermonprez, P., Vargas, P., Moura, I. C., Lennon‐Duménil, A., Seabra, M. C., Raposo, G., & Amigorena, S. (2006) · Cell · doi:10.1016/j.cell.2006.05.035 · Cited by 896 · see citing works
Lipid peroxidation: Mechanisms, inhibition, and biological effects
Niki, E., Yoshida, Y., Saito, Y., & Noguchi, N. (2005) · Biochemical and Biophysical Research Communications · doi:10.1016/j.bbrc.2005.08.072 · Cited by 877 · see citing works
Genetically elevated C-reactive protein and ischemic vascular disease
Zacho, J., Tybjærg-Hansen, A., Jensen, J. S., Grande, P., Sillesen, H., & Nordestgaard, B. G. (2008) · New England Journal of Medicine · doi:10.1056/nejmoa0707402 · Cited by 839 · see citing works
Binder, C. J., Hörkkö, S., Dewan, A. K., Chang, M.-K., Kieu, E., Goodyear, C. S., Shaw, P. X., Palinski, W., Witztum, J. L., & Silverman, G. J. (2003) · Nature Medicine · doi:10.1038/nm876 · Cited by 735 · see citing works
Self-citationTaylor, P. R., Carugati, A., Fadok, V. A., Cook, H. T., Andrews, M., Carroll, M. C., Savill, J., Henson, P. M., Botto, M., & Walport, M. J. (2000) · The Journal of Experimental Medicine · doi:10.1084/jem.192.3.359 · Cited by 724 · see citing works
Gershov, D., Kim, S., Brot, N., & Elkon, K. B. (2000) · The Journal of Experimental Medicine · doi:10.1084/jem.192.9.1353 · Cited by 695 · see citing works
Shaw, P. X., Hörkkö, S., Chang, M.-K., Curtiss, L. K., Palinski, W., Silverman, G. J., & Witztum, J. L. (2000) · Journal of Clinical Investigation · doi:10.1172/jci8472 · Cited by 674 · see citing works
Self-citationImmune Effector Mechanisms Implicated in Atherosclerosis: From Mice to Humans
Libby, P., Lichtman, A. H., & Hansson, G. K. (2013) · Immunity · doi:10.1016/j.immuni.2013.06.009 · Cited by 667 · see citing works
Regulation of Reactive Oxygen Species Generation in Cell Signaling
Bae, Y. S., Oh, H., Rhee, S. G., & Yoo, Y. D. (2011) · Molecules and Cells · doi:10.1007/s10059-011-0276-3 · Cited by 660 · see citing works
Miller, Y. I., Choi, S.-H., Wiesner, P., Fang, L., Harkewicz, R., Hartvigsen, K., Boullier, A., Gonen, A., Diehl, C. J., Que, X., et al. (2011) · Circulation Research · doi:10.1161/circresaha.110.223875 · Cited by 654 · see citing works
Self-citationC-reactive protein: Ligands, receptors and role in inflammation
Marnell, L. L., Mold, C., & Clos, T. W. D. (2005) · Clinical Immunology · doi:10.1016/j.clim.2005.08.004 · Cited by 625 · see citing works
Generation and Biological Activities of Oxidized Phospholipids
Bochkov, V. N., Oskolkova, O., Birukov, K. G., Levonen, A., Binder, C. J., & Stöckl, J. (2009) · Antioxidants and Redox Signaling · doi:10.1089/ars.2009.2597 · Cited by 611 · see citing works
Self-citationPalinski, W., Hörkkö, S., Miller, E., Steinbrecher, U., Powell, H., Curtiss, L., & Witztum, J. (1996) · Journal of Clinical Investigation · doi:10.1172/jci118853 · Cited by 593 · see citing works
Self-citationHörkkö, S., Bird, D. A., Miller, E. R., Itabe, H., Leitinger, N., Subbanagounder, G., Berliner, J. A., Friedman, P., Dennis, E. A., Curtiss, L. K., et al. (1999) · Journal of Clinical Investigation · doi:10.1172/jci4533 · Cited by 559 · see citing works
Self-citationBeginnings of a Good Apoptotic Meal: The Find-Me and Eat-Me Signaling Pathways
Ravichandran, K. S. (2011) · Immunity · doi:10.1016/j.immuni.2011.09.004 · Cited by 559 · see citing works
Besler, C., Heinrich, K., Rohrer, L., Doerries, C., Riwanto, M., Shih, D. M., Chroni, A., Yonekawa, K., Stein, S., Schaefer, N., et al. (2011) · Journal of Clinical Investigation · doi:10.1172/jci42946 · Cited by 535 · see citing works
Complement factor H binds malondialdehyde epitopes and protects from oxidative stress
Weismann, D., Hartvigsen, K., Lauer, N., Bennett, K. L., Scholl, H. P. N., Issa, P. C., Cano, M., Brandstätter, H., Tsimikas, S., Skerka, C., et al. (2011) · Nature · doi:10.1038/nature10449 · Cited by 533 · see citing works
Self-citationRegulated cell death and inflammation: an auto-amplification loop causes organ failure
Linkermann, A., Stockwell, B. R., Krautwald, S., & Anders, H.-J. (2014) · Nature Reviews Immunology · doi:10.1038/nri3743 · Cited by 522 · see citing works
Chang, M.-K., Binder, C. J., Torzewski, M., & Witztum, J. L. (2002) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.192399699 · Cited by 517 · see citing works
Self-citationSeimon, T. A., Nadolski, M. J., Liao, X., Magallon, J., Nguyen, M. T., Feric, N. T., Koschinsky, M. L., Harkewicz, R., Witztum, J. L., Tsimikas, S., et al. (2010) · Cell Metabolism · doi:10.1016/j.cmet.2010.09.010 · Cited by 478 · see citing works
Self-citationOxidation-specific epitopes are dominant targets of innate natural antibodies in mice and humans
Chou, M.-Y., Fogelstrand, L., Hartvigsen, K., Hansen, L. F., Woelkers, D., Shaw, P. X., Choi, J., Perkmann, T., Bäckhed, F., Miller, Y. I., et al. (2009) · Journal of Clinical Investigation · doi:10.1172/jci36800 · Cited by 468 · see citing works
Self-citationOxidized Low-Density Lipoprotein and Atherosclerosis
Steinberg, D. H., & Witztum, J. L. (2010) · Arteriosclerosis Thrombosis and Vascular Biology · doi:10.1161/atvbaha.108.179697 · Cited by 460 · see citing works
Self-citationChang, M.-K., Bergmark, C., Laurila, A., Hörkkö, S., Han, K., Friedman, P., Dennis, E. A., & Witztum, J. L. (1999) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.96.11.6353 · Cited by 456 · see citing works
Self-citationDeletion of LOX-1 Reduces Atherogenesis in LDLR Knockout Mice Fed High Cholesterol Diet
Mehta, J. L., Sanada, N., Hu, C. P., Chen, J., Dandapat, A., Sugawara, F., Satoh, H., Inoue, K., Kawase, Y., Jishage, K.-I., et al. (2007) · Circulation Research · doi:10.1161/circresaha.107.149724 · Cited by 444 · see citing works
Oxidative stress induces angiogenesis by activating TLR2 with novel endogenous ligands
West, X. Z., Malinin, N. L., Merkulova, A. A., Tischenko, M., Kerr, B. A., Borden, E. C., Podrez, E. A., Salomon, R. G., & Byzova, T. V. (2010) · Nature · doi:10.1038/nature09421 · Cited by 431 · see citing works
Greenberg, M. E., Sun, M., Zhang, R., Febbraio, M., Silverstein, R., & Hazen, S. L. (2006) · The Journal of Experimental Medicine · doi:10.1084/jem.20060370 · Cited by 430 · see citing works
Doyle, S., Campbell, M., Ozaki, E., Salomon, R. G., Mori, A., Kenna, P. F., Farrar, G. J., Kiang, A., Humphries, M. M., Lavelle, E. C., et al. (2012) · Nature Medicine · doi:10.1038/nm.2717 · Cited by 418 · see citing works
Antioxidant Vitamin Supplements and Cardiovascular Disease
Kris‐Etherton, P. M., Lichtenstein, A. H., Howard, B. V., Steinberg, D. H., & Witztum, J. L. (2004) · Circulation · doi:10.1161/01.cir.0000137822.39831.f1 · Cited by 408 · see citing works
Self-citationFadok, V. A., Warner, M. L., Bratton, D. L., & Henson, P. M. (1998) · PubMed · Cited by 406 · see citing works
Specificity of C-Reactive Protein for Choline Phosphate Residues of Pneumococcal C-Polysaccharide
Volanakis, J. E., & Kaplan, M. H. (1971) · Experimental Biology and Medicine · doi:10.3181/00379727-136-35323 · Cited by 398 · see citing works
25-Hydroxycholesterols in innate and adaptive immunity
Cyster, J. G., Dang, E. V., Reboldi, A., & Yi, T. (2014) · Nature Reviews Immunology · doi:10.1038/nri3755 · Cited by 388 · see citing works
Microparticles, Vascular Function, and Atherothrombosis
Rautou, P., Vion, A.-C., Amabile, N., Chironi, G. N., Simon, A. C., Tedgui, A., & Boulanger, C. M. (2011) · Circulation Research · doi:10.1161/circresaha.110.233163 · Cited by 376 · see citing works
Accelerated development of IgG autoantibodies and autoimmune disease in the absence of secreted IgM
Boes, M. L., Schmidt, T., Linkemann, K., Beaudette-Zlatanova, B. C., Marshak‐Rothstein, A., & Chen, J. (2000) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.97.3.1184 · Cited by 370 · see citing works
Protective role of phospholipid oxidation products in endotoxin-induced tissue damage
Bochkov, V. N., Kadl, A., Huber, J., Грубер, Ф., Binder, B. R., & Leitinger, N. (2002) · Nature · doi:10.1038/nature01023 · Cited by 367 · see citing works
Fadok, V. A., Warner, M. L., Bratton, D. L., & Henson, P. M. (1998) · The Journal of Immunology · doi:10.4049/jimmunol.161.11.6250 · Cited by 353 · see citing works
Apoptotic Cells with Oxidation-specific Epitopes Are Immunogenic and Proinflammatory
Chang, M.-K., Binder, C. J., Miller, Y. I., Subbanagounder, G., Silverman, G. J., Berliner, J. A., & Witztum, J. L. (2004) · The Journal of Experimental Medicine · doi:10.1084/jem.20031763 · Cited by 334 · see citing works
Self-citationBriles, D. E., Forman, C., Hudak, S. A., & Claflin, J. L. (1982) · The Journal of Experimental Medicine · doi:10.1084/jem.156.4.1177 · Cited by 310 · see citing works
The Lipid Whisker Model of the Structure of Oxidized Cell Membranes
Greenberg, M. E., Li, X.-M., Gugiu, B. G., Gu, X., Qin, J., Salomon, R. G., & Hazen, S. L. (2007) · Journal of Biological Chemistry · doi:10.1074/jbc.m707348200 · Cited by 299 · see citing works
Sterols and oxysterols in immune cell function
Spann, N. J., & Glass, C. K. (2013) · Nature Immunology · doi:10.1038/ni.2681 · Cited by 298 · see citing works
B Cells and Humoral Immunity in Atherosclerosis
Tsiantoulas, D., Diehl, C. J., Witztum, J. L., & Binder, C. J. (2014) · Circulation Research · doi:10.1161/circresaha.113.301145 · Cited by 297 · see citing works
Self-citationHuber, J., Vales, A., Mitulović, G., Blumer, M. J. F., Schmid, R., Witztum, J. L., Binder, B. R., & Leitinger, N. (2002) · Arteriosclerosis Thrombosis and Vascular Biology · doi:10.1161/hq0102.101525 · Cited by 296 · see citing works
Self-citationThe Influence of Innate and Adaptive Immune Responses on Atherosclerosis
Witztum, J. L., & Lichtman, A. H. (2013) · Annual Review of Pathology Mechanisms of Disease · doi:10.1146/annurev-pathol-020712-163936 · Cited by 277 · see citing works
Self-citationThe macrophage scavenger receptor at 30 years of age: current knowledge and future challenges
Greaves, D. R., & Gordon, S. (2008) · Journal of Lipid Research · doi:10.1194/jlr.r800066-jlr200 · Cited by 248 · see citing works
Potter, M. J., & Lieberman, R. (1970) · The Journal of Experimental Medicine · doi:10.1084/jem.132.4.737 · Cited by 245 · see citing works
Essential role for MFG-E8 as ligand for αvβ5 integrin in diurnal retinal phagocytosis
Nandrot, E. F., Anand, M., Almeida, D., Atabai, K., Sheppard, D., & Finnemann, S. C. (2007) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0704756104 · Cited by 241 · see citing works
Association of the Toll-Like Receptor 4 Gene Asp299Gly Polymorphism With Acute Coronary Events
Ameziane, N., Beillat, T., Verpillat, P., Chollet‐Martin, S., Aumont, M.-C., Seknadji, P., Lamotte, M., Lebret, D., Ollivier, V., & de Prost, D. (2003) · Arteriosclerosis Thrombosis and Vascular Biology · doi:10.1161/01.atv.0000101191.92392.1d · Cited by 241 · see citing works
Anti-inflammatory circuitry: Lipoxin, aspirin-triggered lipoxins and their receptor ALX
Chiang, N., Arita, M., & Serhan, C. N. (2005) · Prostaglandins, Leukotrienes and Essential Fatty Acids · doi:10.1016/j.plefa.2005.05.003 · Cited by 239 · see citing works
12/15-Lipoxygenase Orchestrates the Clearance of Apoptotic Cells and Maintains Immunologic Tolerance
Uderhardt, S., i, M. H., Oskolkova, O., Aschermann, S., Bicker, W., Ipseiz, N., Sarter, K., Frey, B., Rothe, T., Voll, R. E., et al. (2012) · Immunity · doi:10.1016/j.immuni.2012.03.010 · Cited by 235 · see citing works
Lipoprotein Accumulation in Macrophages via Toll-Like Receptor-4–Dependent Fluid Phase Uptake
Choi, S.-H., Harkewicz, R., Lee, J. H., Boullier, A., Almazan, F., Li, A. C., Witztum, J. L., Bae, Y. S., & Miller, Y. I. (2009) · Circulation Research · doi:10.1161/circresaha.108.192880 · Cited by 227 · see citing works
Self-citationMullick, A. E., Soldau, K., Kiosses, W. B., Bell, T. A., Tobias, P. S., & Curtiss, L. K. (2008) · The Journal of Experimental Medicine · doi:10.1084/jem.20071096 · Cited by 223 · see citing works
Chen, Y., Park, Y., Patel, E. S., & Silverman, G. J. (2009) · The Journal of Immunology · doi:10.4049/jimmunol.0804191 · Cited by 221 · see citing works
Complement and diseases: Defective alternative pathway control results in kidney and eye diseases
Zipfel, P. F., Heinen, S., Józsi, M., & Skerka, C. (2005) · Molecular Immunology · doi:10.1016/j.molimm.2005.06.015 · Cited by 217 · see citing works
C-reactive protein comes of age
Verma, S., Szmitko, P. E., & Ridker, P. M. (2005) · Nature Clinical Practice Cardiovascular Medicine · doi:10.1038/ncpcardio0074 · Cited by 210 · see citing works
Myeloperoxidase, modified lipoproteins, and atherogenesis
Nicholls, S. J., & Hazen, S. L. (2008) · Journal of Lipid Research · doi:10.1194/jlr.r800086-jlr200 · Cited by 209 · see citing works
Role of Phospholipid Oxidation Products in Atherosclerosis
Lee, S., Birukov, K. G., Romanoski, C. E., Springstead, J. R., Lusis, A. J., & Berliner, J. A. (2012) · Circulation Research · doi:10.1161/circresaha.111.256859 · Cited by 206 · see citing works
Role of complement and complement regulators in the removal of apoptotic cells
Trouw, L. A., Blom, A. M., & Gasque, P. (2007) · Molecular Immunology · doi:10.1016/j.molimm.2007.09.008 · Cited by 192 · see citing works
Boullier, A., Gillotte, K. L., Hörkkö, S., Green, S. R., Friedman, P., Dennis, E. A., Witztum, J. L., Steinberg, D. H., & Quehenberger, O. (2000) · Journal of Biological Chemistry · doi:10.1074/jbc.275.13.9163 · Cited by 190 · see citing works
Self-citationShechter, I., Fogelman, A. M., Haberland, M. E., Seager, J., Hokom, M. M., & Edwards, P. A. (1981) · Journal of Lipid Research · doi:10.1016/s0022-2275(20)34741-6 · Cited by 183 · see citing works
Faria‐Neto, J. R., Chyu, K., Li, X., Dimayuga, P. C., Ferreira, C., Yano, J., Cercek, B., & Shah, P. K. (2006) · Atherosclerosis · doi:10.1016/j.atherosclerosis.2005.11.033 · Cited by 182 · see citing works
Oxidation‐specific epitopes are important targets of innate immunity
Chou, M. ‐., Hartvigsen, K., Hansen, L. F., Fogelstrand, L., Shaw, P. X., Boullier, A., Binder, C. J., & Witztum, J. L. (2008) · Journal of Internal Medicine · doi:10.1111/j.1365-2796.2008.01968.x · Cited by 179 · see citing works
Self-citationThe innate immune response to products of phospholipid peroxidation
Weismann, D., & Binder, C. J. (2012) · Biochimica et Biophysica Acta (BBA) - Biomembranes · doi:10.1016/j.bbamem.2012.01.018 · Cited by 172 · see citing works
Self-citationWalton, K. A., Hsieh, X., Gharavi, N. M., Wang, S. V., Wang, G., Yeh, M. W., Cole, A. L., & Berliner, J. A. (2003) · Journal of Biological Chemistry · doi:10.1074/jbc.m300738200 · Cited by 169 · see citing works
Phosphorylcholine: friend or foe of the immune system?
Harnett, W., & Harnett, M. M. (1999) · Immunology Today · doi:10.1016/s0167-5699(98)01419-4 · Cited by 169 · see citing works
van Dijk, R. A., Kolodgie, F. D., Ravandi, A., Leibundgut, G., Hu, P., Prasad, A., Mahmud, E., Dennis, E. A., Curtiss, L. K., Witztum, J. L., et al. (2012) · Journal of Lipid Research · doi:10.1194/jlr.p030890 · Cited by 169 · see citing works
Self-citationScavenger receptor class B type I as a receptor for oxidized low density lipoprotein
Gillotte-Taylor, K., Boullier, A., Witztum, J. L., Steinberg, D. H., & Quehenberger, O. (2001) · Journal of Lipid Research · doi:10.1016/s0022-2275(20)30281-9 · Cited by 165 · see citing works
Self-citationSun, M., Finnemann, S. C., Febbraio, M., Shan, L., Annangudi, S. P., Podrez, E. A., Hoppe, G., Darrow, R., Organisciak, D. T., Salomon, R. G., et al. (2006) · Journal of Biological Chemistry · doi:10.1074/jbc.m509769200 · Cited by 165 · see citing works
IGM is required for efficient complement mediated phagocytosis of apoptotic cells in vivo
Ogden, C. A., Kowalewski, R., Peng, Y., Montenegro, V., & Elkon, K. B. (2005) · Autoimmunity · doi:10.1080/08916930500124452 · Cited by 163 · see citing works
Gargiulo, S., Gamba, P., Testa, G., Rossin, D., Biasi, F., Poli, G., & Leonarduzzi, G. (2015) · Aging Cell · doi:10.1111/acel.12322 · Cited by 162 · see citing works
Chen, Y., Khanna, S., Goodyear, C. S., Park, Y. B., Raz, E., Thiel, S., Grönwall, C., Vas, J., Boyle, D. L., Corr, M., et al. (2009) · The Journal of Immunology · doi:10.4049/jimmunol.0900948 · Cited by 158 · see citing works
Ryeom, S., Silverstein, R., Scotto, A., & Sparrow, J. (1996) · Journal of Biological Chemistry · doi:10.1074/jbc.271.34.20536 · Cited by 158 · see citing works
Bauer, J., Ripperger, A., Frantz, S., Ergün, S., Schwedhelm, E., & Benndorf, R. A. (2014) · British Journal of Pharmacology · doi:10.1111/bph.12677 · Cited by 154 · see citing works
How does the macula protect itself from oxidative stress?
Handa, J. T. (2012) · Molecular Aspects of Medicine · doi:10.1016/j.mam.2012.03.006 · Cited by 154 · see citing works
Oxidized phospholipid-induced inflammation is mediated by Toll-like receptor 2
Kadl, A., Sharma, P. R., Chen, W., Agrawal, R., Meher, A. K., Rudraiah, S., Grubbs, N., Sharma, R., & Leitinger, N. (2011) · Free Radical Biology and Medicine · doi:10.1016/j.freeradbiomed.2011.08.026 · Cited by 148 · see citing works
Jürgens, G., Chen, Q., Esterbauer, H., Mair, S., Ledinski, G., & Dinges, H. P. (1993) · Arteriosclerosis and Thrombosis A Journal of Vascular Biology · doi:10.1161/01.atv.13.11.1689 · Cited by 148 · see citing works
Trouw, L. A., Bengtsson, A. A., Gelderman, K. A., Dahlbäck, B., Sturfelt, G. K., & Blom, A. M. (2007) · Journal of Biological Chemistry · doi:10.1074/jbc.m704354200 · Cited by 137 · see citing works
Krieg, P., Rosenberger, S. F., de Juanes, S., Latzko, S., Hou, J. L., Dick, A., Kloz, U., van der Hoeven, F., Haußer, I., Esposito, I., et al. (2012) · Journal of Investigative Dermatology · doi:10.1038/jid.2012.250 · Cited by 134 · see citing works
Age-related macular degeneration and the role of the complement system
McHarg, S., Clark, S. J., Day, A. J., & Bishop, P. N. (2015) · Molecular Immunology · doi:10.1016/j.molimm.2015.02.032 · Cited by 126 · see citing works
Phosphocholine as a pattern recognition ligand for CD36
Boullier, A., Friedman, P., Harkewicz, R., Hartvigsen, K., Green, S. R., Almazan, F., Dennis, E. A., Steinberg, D. H., Witztum, J. L., & Quehenberger, O. (2005) · Journal of Lipid Research · doi:10.1194/jlr.m400496-jlr200 · Cited by 123 · see citing works
Self-citationBieghs, V., Verheyen, F., van Gorp, P. J., Hendrikx, T., Wouters, K., Lütjohann, D., Gijbels, M. J., Febbraio, M., Binder, C. J., Hofker, M. H., et al. (2012) · PLoS ONE · doi:10.1371/journal.pone.0034378 · Cited by 120 · see citing works
Self-citationNETosis and NADPH oxidase: at the intersection of host defense, inflammation, and injury
Almyroudis, N. G., Grimm, M. J., Davidson, B. A., Röhm, M., Urban, C. F., & Segal, B. H. (2013) · Frontiers in Immunology · doi:10.3389/fimmu.2013.00045 · Cited by 119 · see citing works
Tsiantoulas, D., Perkmann, T., Afonyushkin, T., Mangold, A., Prohaska, T. A., Papac-Miličević, N., Millischer, V., Bartel, C., Hörkkö, S., Boulanger, C. M., et al. (2014) · Journal of Lipid Research · doi:10.1194/jlr.p054569 · Cited by 118 · see citing works
Self-citation12/15-lipoxygenase–mediated enzymatic lipid oxidation regulates DC maturation and function
Rothe, T., Грубер, Ф., Uderhardt, S., Ipseiz, N., Rößner, S., Oskolkova, O., Blüml, S., Leitinger, N., Bicker, W., Bochkov, V. N., et al. (2015) · Journal of Clinical Investigation · doi:10.1172/jci78490 · Cited by 113 · see citing works
Harkewicz, R., Hartvigsen, K., Almazan, F., Dennis, E. A., Witztum, J. L., & Miller, Y. I. (2008) · Journal of Biological Chemistry · doi:10.1074/jbc.m709006200 · Cited by 108 · see citing works
Self-citationBorisenko, G. G., Iverson, S. L., Ahlberg, S., Kagan, V. E., & Fadeel, B. (2004) · Cell Death and Differentiation · doi:10.1038/sj.cdd.4401421 · Cited by 106 · see citing works
Biró, É., Nieuwland, R., Tak, P. P., PRONK, L. M., Schaap, M. C. L., Sturk, A., & Hack, C. E. (2007) · Annals of the Rheumatic Diseases · doi:10.1136/ard.2006.061309 · Cited by 102 · see citing works
Non-alcoholic steatohepatitis: The role of oxidized low-density lipoproteins
Walenbergh, S. M. A., Koek, G. H., Bieghs, V., & Shiri‐Sverdlov, R. (2012) · Journal of Hepatology · doi:10.1016/j.jhep.2012.11.014 · Cited by 101 · see citing works
The role of IgM antibodies in the recognition and clearance of apoptotic cells
Peng, Y., Kowalewski, R., Kim, S., & Elkon, K. B. (2005) · Molecular Immunology · doi:10.1016/j.molimm.2004.07.045 · Cited by 100 · see citing works
Negative Regulation of Phagocytosis in Murine Macrophages by the Src Kinase Family Member, Fgr
Gresham, H. D., Dale, B. M., Potter, J. W., Chang, P. W., Vines, C. M., Lowell, C. A., Lagenaur, C. F., & Willman, C. L. (2000) · The Journal of Experimental Medicine · doi:10.1084/jem.191.3.515 · Cited by 99 · see citing works
Litvack, M. L., & Palaniyar, N. (2010) · Innate Immunity · doi:10.1177/1753425910369271 · Cited by 98 · see citing works
Cyclopentenone Prostaglandins as Potential Inducers of Phase II Detoxification Enzymes
Kawamoto, Y., Nakamura, Y., Naito, Y., Torii, Y., Kumagai, T., Osawa, T., Ohigashi, H., Satoh, K., Imagawa, M., & Uchida, K. (2000) · Journal of Biological Chemistry · doi:10.1074/jbc.275.15.11291 · Cited by 98 · see citing works
O’Donnell, V. B., & Murphy, R. C. (2012) · Blood · doi:10.1182/blood-2012-04-402826 · Cited by 94 · see citing works
Bieghs, V., van Gorp, P. J., Walenbergh, S. M. A., Gijbels, M. J., Verheyen, F., Buurman, W. A., Briles, D. E., Hofker, M. H., Binder, C. J., & Shiri‐Sverdlov, R. (2012) · Hepatology · doi:10.1002/hep.25660 · Cited by 94 · see citing works
Self-citationHuman Retinal Pigment Epithelial Cells Express Scavenger Receptors BI and BII
Duncan, K. G., Bailey, K. R., Kane, J. P., & Schwartz, D. M. (2002) · Biochemical and Biophysical Research Communications · doi:10.1006/bbrc.2002.6756 · Cited by 91 · see citing works
Clark, S., Thomas, C. P., Hammond, V. J., Aldrovandi, M., Wilkinson, G. W. G., Hart, K. W., Murphy, R. C., Collins, P. W., & O’Donnell, V. B. (2013) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1222419110 · Cited by 90 · see citing works
Bretscher, P., Egger, J., Shamshiev, A. T., Trötzmüller, M., Köfeler, H. C., Carreira, E. M., Köpf, M., & Freigang, S. (2015) · EMBO Molecular Medicine · doi:10.15252/emmm.201404702 · Cited by 88 · see citing works
Fadeel, B., Xue, D., & Kagan, V. E. (2010) · Biochemical and Biophysical Research Communications · doi:10.1016/j.bbrc.2010.02.106 · Cited by 84 · see citing works
Oksjoki, R. K., Jarva, H., Kovanen, P. T., Laine, P., Meri, S., & Pentikäinen, M. O. (2003) · Arteriosclerosis Thrombosis and Vascular Biology · doi:10.1161/01.atv.0000057808.91263.a4 · Cited by 78 · see citing works
Tuominen, A., Miller, Y. I., Hansen, L. F., Kesäniemi, Y. A., Witztum, J. L., & Hörkkö, S. (2006) · Arteriosclerosis, Thrombosis, and Vascular Biology · doi:10.1161/01.atv.0000233333.07991.4a · Cited by 78 · see citing works
Self-citationCholesterol-Induced Membrane Microvesicles As Novel Carriers of Damage–Associated Molecular Patterns
Liu, M., Scalia, R. G., Mehta, J. L., & Williams, K. J. (2012) · Arteriosclerosis Thrombosis and Vascular Biology · doi:10.1161/atvbaha.112.255471 · Cited by 75 · see citing works
Gruber, S., Hendrikx, T., Tsiantoulas, D., Ozsvár-Kozma, M., Göderle, L., Mallat, Z., Witztum, J. L., Shiri‐Sverdlov, R., Nitschke, L., & Binder, C. J. (2016) · Cell Reports · doi:10.1016/j.celrep.2016.02.027 · Cited by 75 · see citing works
Self-citationFcγ Receptors and Ligands and Cardiovascular Disease
Tanigaki, K., Sundgren, N. C., Khera, A., Vongpatanasin, W., Mineo, C., & Shaul, P. W. (2015) · Circulation Research · doi:10.1161/circresaha.116.302795 · Cited by 72 · see citing works
Structural Identification and Cardiovascular Activities of Oxidized Phospholipids
Salomon, R. G. (2012) · Circulation Research · doi:10.1161/circresaha.112.275388 · Cited by 70 · see citing works
Oxidized but not native cardiolipin has pro-inflammatory effects, which are inhibited by Annexin A5
Wan, M., Hua, X., Su, J., Thiagarajan, D., Frostegård, A. G., Haeggström, J. Z., & Frostegård, J. (2014) · Atherosclerosis · doi:10.1016/j.atherosclerosis.2014.05.913 · Cited by 68 · see citing works
Amarilyo, G., Verbovetski, I., Atallah, M., Grau, A., Wiser, G., Gill, O., Ben‐Neriah, Y., & Mevorach, D. (2009) · European Journal of Immunology · doi:10.1002/eji.200838951 · Cited by 67 · see citing works
Lauer, N., Mihlan, M., Hartmann, A., Schlötzer-Schrehardt, U. M., Keilhauer, C. N., Scholl, H. P. N., Issa, P. C., Holz, F. G., Weber, B. H. F., Skerka, C., et al. (2011) · The Journal of Immunology · doi:10.4049/jimmunol.1002488 · Cited by 66 · see citing works
Turunen, S. P., Kummu, O., Harila, K., Veneskoski, M., Soliymani, R., Baumann, M., Pussinen, P. J., & Hörkkö, S. (2012) · PLoS ONE · doi:10.1371/journal.pone.0034910 · Cited by 59 · see citing works
Peptide mimotopes of malondialdehyde epitopes for clinical applications in cardiovascular disease
Amir, S., Hartvigsen, K., Gonen, A., Leibundgut, G., Que, X., Jensen‐Jarolim, E., Wagner, O. F., Tsimikas, S., Witztum, J. L., & Binder, C. J. (2012) · Journal of Lipid Research · doi:10.1194/jlr.m025445 · Cited by 56 · see citing works
Self-citationDuryee, M. J., Freeman, T. L., Willis, M. S., Hunter, C. D., Hamilton, B. C., Suzuki, H., Tuma, D. J., Klassen, L. W., & Thiele, G. M. (2005) · Molecular Pharmacology · doi:10.1124/mol.105.016121 · Cited by 51 · see citing works
Veneskoski, M., Turunen, S. P., Kummu, O., Nissinen, A. E. T., Rannikko, S., Levonen, A., & Hörkkö, S. (2011) · Free Radical Biology and Medicine · doi:10.1016/j.freeradbiomed.2011.05.029 · Cited by 51 · see citing works
Salomon, R. G., Hong, L., & Hollyfield, J. G. (2011) · Chemical Research in Toxicology · doi:10.1021/tx200206v · Cited by 50 · see citing works
Choi, S., Yin, H., Ravandi, A., Armando, A. M., Dumlao, D. S., Kim, J., Almazan, F., Taylor, A. M., McNamara, C. A., Tsimikas, S., et al. (2013) · PLoS ONE · doi:10.1371/journal.pone.0083145 · Cited by 50 · see citing works
Self-citationHormetic and anti-inflammatory properties of oxidized phospholipids
Mauerhofer, C., Philippova, M., Oskolkova, O., & Bochkov, V. N. (2016) · Molecular Aspects of Medicine · doi:10.1016/j.mam.2016.02.003 · Cited by 49 · see citing works
Malondialdehyde–acetaldehyde-adducted protein inhalation causes lung injury
Wyatt, T. A., Kharbanda, K. K., McCaskill, M. L., Tuma, D. J., Yanov, D. A., DeVasure, J. M., & Sisson, J. H. (2011) · Alcohol · doi:10.1016/j.alcohol.2011.09.001 · Cited by 47 · see citing works
Biswas, S., Liang, X., Panigrahi, S., Zimman, A., Wang, H., Yakubenko, V. P., Byzova, T. V., Salomon, R. G., & Podrez, E. A. (2016) · Blood · doi:10.1182/blood-2015-08-664300 · Cited by 47 · see citing works
Human complement Factor H modulates C1q-mediated phagocytosis of apoptotic cells
Kang, Y.-H., Urban, B. C., Sim, R. B., & Kishore, U. (2011) · Immunobiology · doi:10.1016/j.imbio.2011.10.008 · Cited by 44 · see citing works
Li, X.-M., Salomon, R. G., Qin, J., & Hazen, S. L. (2007) · Biochemistry · doi:10.1021/bi700163y · Cited by 40 · see citing works
Kumano-Kuramochi, M., Shimozu, Y., Wakita, C., Ohnishi‐Kameyama, M., Shibata, T., Matsunaga, S., Takano‐Ishikawa, Y., Watanabe, J., Goto, M., Xie, Q., et al. (2011) · Biochemical Journal · doi:10.1042/bj20111029 · Cited by 40 · see citing works
Aredo, B., Li, T., Chen, X., Zhang, K., Wang, C. X.-Z., Gou, D., Zhao, B., He, Y.-G., & Ufret-Vincenty, R. L. (2015) · Investigative Ophthalmology & Visual Science · doi:10.1167/iovs.14-16089 · Cited by 40 · see citing works
Wang, G., Li, H., & Khan, M. F. (2012) · Free Radical Research · doi:10.3109/10715762.2012.727209 · Cited by 37 · see citing works
Hyvärinen, S., Uchida, K., Varjosalo, M. T., Jokela, R., & Jokiranta, T. S. (2013) · Journal of Biological Chemistry · doi:10.1074/jbc.m113.527416 · Cited by 35 · see citing works
Sofat, R., Casas, J. P., Meena Kumari, B., Talmud, P. J., Ireland, H., Mika Kivimaki, B., Marmot, M. G., Hughes, A. D., Thom, S., Ebrahim, S. B. J., et al. (2010) · Atherosclerosis · doi:10.1016/j.atherosclerosis.2010.07.021 · Cited by 30 · see citing works
Receptor-Mediated Mechanism Controlling Tissue Levels of Bioactive Lipid Oxidation Products
Kim, Y.-W., Yakubenko, V. P., West, X. Z., Gugiu, G. B., Renganathan, K., Biswas, S., Gao, D., Crabb, J. W., Salomon, R. G., Podrez, E. A., et al. (2015) · Circulation Research · doi:10.1161/circresaha.117.305925 · Cited by 30 · see citing works
WAVE1 mediates suppression of phagocytosis by phospholipid-derived DAMPs
Matt, U., Sharif, O., Martins, R., Furtner, T., Langeberg, L. K., Gawish, R., Elbau, I., Zivkovic, A., Lakovits, K., Oskolkova, O., et al. (2013) · Journal of Clinical Investigation · doi:10.1172/jci60681 · Cited by 28 · see citing works
Self-citationSaeed, A. M., Duffort, S., Ivanov, D., Wang, H., Laird, J. M., Salomon, R. G., Cruz‐Guilloty, F., & Perez, V. L. (2014) · PLoS ONE · doi:10.1371/journal.pone.0106421 · Cited by 27 · see citing works
CD36 Expression in Sltered in Retinal Pigment Epithelial Cells of the RCS Rat
Sparrow, J. R., Ryeom, S. W., Abumrad, N. A., Ibrahimi, A., & Silverstein, R. L. (1997) · Experimental Eye Research · doi:10.1006/exer.1996.0177 · Cited by 26 · see citing works
Wang, H., Linetsky, M. D., Guo, J., Choi, J., Hong, L., Chamberlain, A. S., Howell, S. J., Howes, A. M., & Salomon, R. G. (2015) · Chemical Research in Toxicology · doi:10.1021/acs.chemrestox.5b00001 · Cited by 17 · see citing works
Oxidized phospholipid signaling in immune cells
Thomas, C. P., & O’Donnell, V. B. (2012) · Current Opinion in Pharmacology · doi:10.1016/j.coph.2012.02.013 · Cited by 17 · see citing works
Flagged first, then by citations
Cited by
Sorted by citations
Borén, J., Chapman, M. J., Krauss, R. M., Packard, C. J., Bentzon, J. F., Binder, C. J., Daemen, M. J., Demer, L. L., Hegele, R. A., Nicholls, S. J., et al. (2020) · European Heart Journal · doi:10.1093/eurheartj/ehz962 · Cited by 1,601 · see citing works
Self-citationRoles of vascular oxidative stress and nitric oxide in the pathogenesis of atherosclerosis
Förstermann, U., Xia, N., & Li, H. (2017) · Circulation Research · doi:10.1161/circresaha.116.309326 · Cited by 1,519 · see citing works
Reyes-Soffer, G., Ginsberg, H. N., Berglund, L., Duell, P. B., Heffron, S. P., Kamstrup, P. R., Lloyd-Jones, D. M., Marcovina, S. M., Yeang, C., Koschinsky, M. L., et al. (2022) · Arteriosclerosis, Thrombosis, and Vascular Biology · doi:10.1161/atv.0000000000000147 · Cited by 836 · see citing works
Xu, S., Chaudhary, O., Rodríguez-Morales, P., Sun, X., Chen, D., Zappasodi, R., Xu, Z. Z., Pinto, A. F. M., Williams, A. E., Schulze, I., et al. (2021) · Immunity · doi:10.1016/j.immuni.2021.05.003 · Cited by 815 · see citing works
Self-citationHow the immune system shapes atherosclerosis: roles of innate and adaptive immunity
Roy, P., Orecchioni, M., & Ley, K. F. (2021) · Nature reviews. Immunology · doi:10.1038/s41577-021-00584-1 · Cited by 584 · see citing works
Oxidized phospholipids are proinflammatory and proatherogenic in hypercholesterolaemic mice
Que, X., Hung, M.-Y., Yeang, C., Gonen, A., Prohaska, T. A., Sun, X., Diehl, C., Määttä, A., Gaddis, D. E., Bowden, K., et al. (2018) · Nature · doi:10.1038/s41586-018-0198-8 · Cited by 529 · see citing works
Self-citationLipid metabolism in sickness and in health: Emerging regulators of lipotoxicity
Yoon, H., Shaw, J. L., Haigis, M. C., & Greka, A. (2021) · Molecular Cell · doi:10.1016/j.molcel.2021.08.027 · Cited by 521 · see citing works
Mechanistic Insights into the Oxidized Low-Density Lipoprotein-Induced Atherosclerosis
Khatana, C., Saini, N. K., Chakrabarti, S., Saini, V., Sharma, A. K., Saini, R. V., & Saini, A. K. (2020) · Oxidative Medicine and Cellular Longevity · doi:10.1155/2020/5245308 · Cited by 481 · see citing works
Therapeutic strategies targeting inflammation and immunity in atherosclerosis: how to proceed?
Engelen, S. E., Robinson, A., Zurke, Y.-X., & Monaco, C. G. (2022) · Nature Reviews Cardiology · doi:10.1038/s41569-021-00668-4 · Cited by 442 · see citing works
Disease tolerance and immunity in host protection against infection
Soares, M. P., Teixeira, L., & Moita, L. F. (2017) · Nature reviews. Immunology · doi:10.1038/nri.2016.136 · Cited by 376 · see citing works
An update on lipid oxidation and inflammation in cardiovascular diseases
Zhong, S., Li, L., Shen, X., Li, Q., Xu, W., Wang, X., Tao, Y., & Yin, H. (2019) · Free Radical Biology and Medicine · doi:10.1016/j.freeradbiomed.2019.03.036 · Cited by 333 · see citing works
ApoE attenuates unresolvable inflammation by complex formation with activated C1q
Yin, C., Ackermann, S., Ma, Z., Mohanta, S. K., Zhang, C., Li, Y., Nietzsche, S., Westermann, M., Peng, L., Hu, D., et al. (2019) · Nature Medicine · doi:10.1038/s41591-018-0336-8 · Cited by 305 · see citing works
Self-citationZhang, X., Sui, S., Wang, L., Li, H., Zhang, L., Xu, S., & Zheng, X. (2020) · Journal of Cellular Physiology · doi:10.1002/jcp.29232 · Cited by 293 · see citing works
The role of B cells in atherosclerosis
Sage, A. P., Tsiantoulas, D., Binder, C. J., & Mallat, Z. (2019) · Nature Reviews Cardiology · doi:10.1038/s41569-018-0106-9 · Cited by 298 · see citing works
Self-citationOxidized phospholipids as a unifying theory for lipoprotein(a) and cardiovascular disease
Boffa, M. B., & Koschinsky, M. L. (2019) · Nature Reviews Cardiology · doi:10.1038/s41569-018-0153-2 · Cited by 289 · see citing works
Understanding the extracellular vesicle surface for clinical molecular biology
Hallal, S. M., Tűzesi, Á., Grau, G. E., Buckland, M. E., & Alexander, K. L. (2022) · Journal of Extracellular Vesicles · doi:10.1002/jev2.12260 · Cited by 246 · see citing works
Understanding the role of neutrophils in acute respiratory distress syndrome
Yang, S.-C., Tsai, Y.-F., Pan, Y.-L., & Hwang, T. (2020) · Biomedical Journal · doi:10.1016/j.bj.2020.09.001 · Cited by 234 · see citing works
Metabolic drivers of non-alcoholic fatty liver disease
Bence, K. K., & Birnbaum, M. J. (2020) · Molecular Metabolism · doi:10.1016/j.molmet.2020.101143 · Cited by 223 · see citing works
The Neutrophil’s Choice: Phagocytose vs Make Neutrophil Extracellular Traps
Manfredi, A. A., Ramirez, G. A., Rovere, P. Q., & Maugeri, N. (2018) · Frontiers in Immunology · doi:10.3389/fimmu.2018.00288 · Cited by 220 · see citing works
Origin and Consequences of Necroinflammation
Sarhan, M., Land, W. G., Tonnus, W., Hugo, C., & Linkermann, A. (2018) · Physiological Reviews · doi:10.1152/physrev.00041.2016 · Cited by 210 · see citing works
Neutralization of Oxidized Phospholipids Ameliorates Non-alcoholic Steatohepatitis
Sun, X., Seidman, J. S., Zhao, P., Troutman, T. D., Spann, N. J., Que, X., Zhou, F., Liao, Z., Pasillas, M. P., Yang, X., et al. (2019) · Cell Metabolism · doi:10.1016/j.cmet.2019.10.014 · Cited by 205 · see citing works
Self-citationLee, S., Devanney, N. A., Golden, L. R., Smith, C. T., Schwartz, J. L., Walsh, A. E., Clarke, H. A., Goulding, D. S., Allenger, E. J., Morillo-Segovia, G., et al. (2023) · Cell Reports · doi:10.1016/j.celrep.2023.112196 · Cited by 203 · see citing works
Small Extracellular Vesicles Have GST Activity and Ameliorate Senescence-Related Tissue Damage
Fafián-Labora, J. A., Rodríguez-Navarro, J. A., & O’Loghlen, A. (2020) · Cell Metabolism · doi:10.1016/j.cmet.2020.06.004 · Cited by 203 · see citing works
Chen, X., Xie, N., Feng, L., Huang, Y., Wu, Y., Zhu, H., Tang, J., & Zhang, Y. (2024) · Chinese Medical Journal · doi:10.1097/cm9.0000000000003230 · Cited by 186 · see citing works
Davidson, S. M., Boulanger, C. M., Aïkawa, E., Badimón, L., Barile, L., Binder, C. J., Brisson, A. R., Buzás, E. I., Emanueli, C., Jansen, F., et al. (2022) · Cardiovascular Research · doi:10.1093/cvr/cvac031 · Cited by 174 · see citing works
Self-citationROS signaling in innate immunity via oxidative protein modifications
Manoharan, R. R., Prasad, A., Pospı́šil, P., & Kzhyshkowska, J. G. (2024) · Frontiers in Immunology · doi:10.3389/fimmu.2024.1359600 · Cited by 163 · see citing works
Molecular Mechanisms of Neutrophil Extracellular Trap (NETs) Degradation
Demkow, U. A. (2023) · International Journal of Molecular Sciences · doi:10.3390/ijms24054896 · Cited by 157 · see citing works
Autoimmune diseases and atherosclerotic cardiovascular disease
Porsch, F., & Binder, C. J. (2024) · Nature Reviews Cardiology · doi:10.1038/s41569-024-01045-7 · Cited by 151 · see citing works
Self-citationImmunobiology of Atherosclerosis: A Complex Net of Interactions
Herrero‐Fernández, B., Gómez-Bris, R., Somovilla-Crespo, B., & González, J. M. (2019) · International Journal of Molecular Sciences · doi:10.3390/ijms20215293 · Cited by 152 · see citing works
Oxidized phospholipids in cardiovascular disease
Tsimikas, S., & Witztum, J. L. (2023) · Nature Reviews Cardiology · doi:10.1038/s41569-023-00937-4 · Cited by 158 · see citing works
Self-citationSerbulea, V., Upchurch, C. M., Schappe, M. S., Voigt, P. E., DeWeese, D. E., Desai, B. N., Meher, A. K., & Leitinger, N. (2018) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1800544115 · Cited by 146 · see citing works
Connecting the “Dots”: From Free Radical Lipid Autoxidation to Cell Pathology and Disease
Foret, M. K., Lincoln, R., Carmo, S. D., Cuello, A. C., & Cosa, G. (2020) · Chemical Reviews · doi:10.1021/acs.chemrev.0c00761 · Cited by 144 · see citing works
Context-Dependent Role of Oxidized Lipids and Lipoproteins in Inflammation
Miller, Y. I., & Shyy, J. Y.-J. (2016) · Trends in Endocrinology and Metabolism · doi:10.1016/j.tem.2016.11.002 · Cited by 140 · see citing works
Oxidized low‐density lipoprotein in inflammation‐driven thrombosis
Obermayer, G., Afonyushkin, T., & Binder, C. J. (2018) · Journal of Thrombosis and Haemostasis · doi:10.1111/jth.13925 · Cited by 134 · see citing works
Self-citationPCSK9 inhibition and inflammation: A narrative review
Ruscica, M., Tokgözoğlu, L. S., Corsini, A., & Sirtori, C. R. (2019) · Atherosclerosis · doi:10.1016/j.atherosclerosis.2019.07.015 · Cited by 130 · see citing works
ALDH4A1 is an atherosclerosis auto-antigen targeted by protective antibodies
Lorenzo, C., Delgado, P., Busse, C. E., Sanz‐Bravo, A., Martos-Folgado, I., Bonzón‐Kulichenko, E., Ferrarini, A., Gonzalez-Valdes, I. B., Mur, S. M., Roldán-Montero, R., et al. (2020) · Nature · doi:10.1038/s41586-020-2993-2 · Cited by 128 · see citing works
Pleiotropic effects of oxidized phospholipids
Bochkov, V. N., Gesslbauer, B., Mauerhofer, C., Philippova, M., Erné, P., & Oskolkova, O. (2016) · Free Radical Biology and Medicine · doi:10.1016/j.freeradbiomed.2016.12.034 · Cited by 125 · see citing works
Neutrophil Extracellular Trap Degradation by Differently Polarized Macrophage Subsets
Haider, P., Kral-Pointner, J. B., Mayer, J., Richter, M., Kaun, C., Brostjan, C., Eilenberg, W. H., Fischer, M. B., Speidl, W. S., Hengstenberg, C., et al. (2020) · Arteriosclerosis Thrombosis and Vascular Biology · doi:10.1161/atvbaha.120.314883 · Cited by 123 · see citing works
Stamenković, A., O’Hara, K. A., Nelson, D. C., Maddaford, T. G., Edel, A. L., Maddaford, G. G., Dibrov, E., Aghanoori, M., Kirshenbaum, L. A., Fernyhough, P., et al. (2021) · American Journal of Physiology-Heart and Circulatory Physiology · doi:10.1152/ajpheart.00237.2020 · Cited by 124 · see citing works
TREM2 protects from atherosclerosis by limiting necrotic core formation
Piollet, M., Porsch, F., Rizzo, G., Kapser, F., Schulz, D., Kiss, M. G., Schlepckow, K., Morenas‐Rodríguez, E., Sen, M. O., Gropper, J., et al. (2024) · Nature Cardiovascular Research · doi:10.1038/s44161-024-00429-9 · Cited by 130 · see citing works
Self-citationRedox-dependent thiol modifications: implications for the release of extracellular vesicles
Benedikter, B. J., Weseler, A. R., Wouters, E. F. �., Savelkoul, P. H. M., Rohde, G. G. U., & Stassen, F. R. M. (2018) · Cellular and Molecular Life Sciences · doi:10.1007/s00018-018-2806-z · Cited by 117 · see citing works
NLRP3 inflammasome: The rising star in cardiovascular diseases
Zheng, Y., Li, X., Dong, N., & Li, F. (2022) · Frontiers in Cardiovascular Medicine · doi:10.3389/fcvm.2022.927061 · Cited by 109 · see citing works
Immunometabolic rewiring of tubular epithelial cells in kidney disease
van der Rijt, S., Leemans, J. C., Florquin, S., Houtkooper, R. H., & Tammaro, A. (2022) · Nature Reviews Nephrology · doi:10.1038/s41581-022-00592-x · Cited by 102 · see citing works
The Role of Oxidative Stress in NAFLD–NASH–HCC Transition—Focus on NADPH Oxidases
Gabbia, D., Cannella, L., & Martin, S. D. (2021) · Biomedicines · doi:10.3390/biomedicines9060687 · Cited by 100 · see citing works
Metabolism-Associated Molecular Patterns (MAMPs)
Wang, X., Wang, Y., Antony, V., Sun, H., & Liang, G. (2020) · Trends in Endocrinology and Metabolism · doi:10.1016/j.tem.2020.07.001 · Cited by 94 · see citing works
Apolipoprotein B-containing lipoproteins in atherogenesis
Borén, J., Packard, C. J., & Binder, C. J. (2025) · Nature Reviews Cardiology · doi:10.1038/s41569-024-01111-0 · Cited by 104 · see citing works
Self-citationOxidative stress biomarker triggered multiplexed tool for auxiliary diagnosis of atherosclerosis
Ma, Y., Sun, W. Y., Ye, Z., Liu, L., Li, M., Shang, J., Xu, X., Cao, H., Xu, L., Liu, Y., et al. (2023) · Science Advances · doi:10.1126/sciadv.adh1037 · Cited by 95 · see citing works
Li, Q., Shi, C., Wang, M., Zhou, M., Liang, M., Zhang, T., Yuan, E., Wang, Z., Yao, M., & Ren, J. (2019) · Journal of Functional Foods · doi:10.1016/j.jff.2018.11.024 · Cited by 94 · see citing works
Zhang, J., Wang, Y., Fan, M., Guan, Y., Zhang, W., Huang, F., Zhang, Z., Li, X., Yuan, B., Liu, W., et al. (2024) · Cell Metabolism · doi:10.1016/j.cmet.2024.05.008 · Cited by 94 · see citing works
The multifaceted impact of complement on atherosclerosis
Kiss, M. G., & Binder, C. J. (2022) · Atherosclerosis · doi:10.1016/j.atherosclerosis.2022.03.014 · Cited by 92 · see citing works
Self-citationReduction of myocardial ischaemia–reperfusion injury by inactivating oxidized phospholipids
Yeang, C., Hasanally, D., Que, X., Hung, M., Stamenković, A., Chan, D., Chaudhary, R., Margulets, V., Edel, A. L., Hoshijima, M., et al. (2018) · Cardiovascular Research · doi:10.1093/cvr/cvy136 · Cited by 92 · see citing works
Self-citationImmunometabolism and immune response regulate macrophage function in atherosclerosis
Xue, S., Su, Z., & Liu, D. (2023) · Ageing Research Reviews · doi:10.1016/j.arr.2023.101993 · Cited by 94 · see citing works
Kotla, S., Singh, N. K., & Rao, G. N. (2016) · Redox Biology · doi:10.1016/j.redox.2016.12.005 · Cited by 90 · see citing works
Recognition of Oxidized Lipids by Macrophages and Its Role in Atherosclerosis Development
Mushenkova, N. V., Bezsonov, E. E., Orekhova, V. A., Попкова, Т. В., Starodubova, A. V., & Orekhov, A. N. (2021) · Biomedicines · doi:10.3390/biomedicines9080915 · Cited by 89 · see citing works
Lipid scavenging macrophages and inflammation
Vogel, A., Brunner, J. S., Hajto, A., Sharif, O., & Schabbauer, G. (2021) · Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids · doi:10.1016/j.bbalip.2021.159066 · Cited by 85 · see citing works
Tsimikas, S. (2019) · Circulation Research · doi:10.1161/circresaha.118.313864 · Cited by 87 · see citing works
Immunometabolic function of cholesterol in cardiovascular disease and beyond
Yvan‐Charvet, L., Bonacina, F., Guinamard, R., & Norata, G. D. (2019) · Cardiovascular Research · doi:10.1093/cvr/cvz127 · Cited by 86 · see citing works
Humoral immunity in atherosclerosis and myocardial infarction: from B cells to antibodies
Porsch, F., Mallat, Z., & Binder, C. J. (2021) · Cardiovascular Research · doi:10.1093/cvr/cvab285 · Cited by 86 · see citing works
Self-citationInterleukin-1β Inhibition for Chronic Kidney Disease in Obese Mice With Type 2 Diabetes
Lei, Y., Devarapu, S. K., Motrapu, M., Cohen, C. D., Lindenmeyer, M. T., Moll, S., Kumar, S. V. R., & Anders, H. (2019) · Frontiers in Immunology · doi:10.3389/fimmu.2019.01223 · Cited by 80 · see citing works
Hypertension and Dyslipidemia: the Two Partners in Endothelium-Related Crime
Dąbrowska, E., & Narkiewicz, K. (2023) · Current Atherosclerosis Reports · doi:10.1007/s11883-023-01132-z · Cited by 89 · see citing works
Modified Lipoproteins Induce Arterial Wall Inflammation During Atherogenesis
Lorey, M. B., Öörni, K., & Kovanen, P. T. (2022) · Frontiers in Cardiovascular Medicine · doi:10.3389/fcvm.2022.841545 · Cited by 80 · see citing works
The effect of oxidized phospholipids on phenotypic polarization and function of macrophages
Serbulea, V., DeWeese, D. E., & Leitinger, N. (2017) · Free Radical Biology and Medicine · doi:10.1016/j.freeradbiomed.2017.02.035 · Cited by 77 · see citing works
Lipoproteins as targets and markers of lipoxidation
Afonso, C. B., & Spickett, C. M. (2018) · Redox Biology · doi:10.1016/j.redox.2018.101066 · Cited by 77 · see citing works
Cavati, G., Pirrotta, F., Merlotti, D., Ceccarelli, E., Calabrese, M., Gennari, L., & Mingiano, C. (2023) · Antioxidants · doi:10.3390/antiox12040928 · Cited by 76 · see citing works
Health Risks of Food Oxidation
Estévez, M., Li, Z., Soladoye, O. P., & Van-Hecke, T. (2017) · Advances in food and nutrition research · doi:10.1016/bs.afnr.2016.12.005 · Cited by 75 · see citing works
Narzt, M.-S., Pils, V., Kremslehner, C., Nagelreiter, I.-M., Schosserer, M., Bessonova, E., Bayer, A., Reifschneider, R., Terlecki-Zaniewicz, L., Waidhofer-Söllner, P., et al. (2021) · Journal of Investigative Dermatology · doi:10.1016/j.jid.2020.11.020 · Cited by 73 · see citing works
Dzobo, K. E., Cupido, A. J., Mol, B. M., Stiekema, L. C. A., Versloot, M., Winkelmeijer, M., Peter, J., Pennekamp, A.-M., Havik, S. R., Vaz, F. M., et al. (2024) · Arteriosclerosis Thrombosis and Vascular Biology · doi:10.1161/atvbaha.123.319937 · Cited by 72 · see citing works
Srikakulapu, P., & McNamara, C. A. (2017) · American Journal of Physiology-Heart and Circulatory Physiology · doi:10.1152/ajpheart.00859.2016 · Cited by 72 · see citing works
Irmscher, S., Brix, S. R., Zipfel, S. L. H., Halder, L. D., Mutlutürk, S., Wulf, S., Girdauskas, E., Reichenspurner, H. C., Stahl, R. A. K., Jungnickel, B., et al. (2019) · Nature Communications · doi:10.1038/s41467-019-10766-0 · Cited by 72 · see citing works
Atherosclerosis: Insights into Vascular Pathobiology and Outlook to Novel Treatments
Wolf, M., & Hunziker, P. (2020) · Journal of Cardiovascular Translational Research · doi:10.1007/s12265-020-09961-y · Cited by 71 · see citing works
Zhao, T. X., Aetesam‐ur‐Rahman, M., Sage, A. P., Victor, S., Kurian, R., Fielding, S., Ait‐Oufella, H., Chiu, Y., Binder, C. J., McKie, M. A., et al. (2021) · Cardiovascular Research · doi:10.1093/cvr/cvab113 · Cited by 71 · see citing works
Self-citationLuo, L., Zang, G., Liu, B., Qin, X., Zhang, Y., Chen, Y., Zhang, H., Wu, W., & Wang, G. (2021) · Theranostics · doi:10.7150/thno.60785 · Cited by 71 · see citing works
The role of reactive oxygen species in bone cell physiology and pathophysiology
Marques-Carvalho, A., Kim, H., & Almeida, M. (2023) · Bone Reports · doi:10.1016/j.bonr.2023.101664 · Cited by 72 · see citing works
Perivascular Adipose Tissue Harbors Atheroprotective IgM-Producing B Cells
Srikakulapu, P., Upadhye, A., Rosenfeld, S. M., Marshall, M. A., McSkimming, C. C., Hickman, A. W., Mauldin, I. S., Ailawadi, G., Lopes, M. B. S., Taylor, A. M., et al. (2017) · Frontiers in Physiology · doi:10.3389/fphys.2017.00719 · Cited by 70 · see citing works
Mast Cells as Potential Accelerators of Human Atherosclerosis—From Early to Late Lesions
Kovanen, P. T. (2019) · International Journal of Molecular Sciences · doi:10.3390/ijms20184479 · Cited by 72 · see citing works
Malondialdehyde epitopes are sterile mediators of hepatic inflammation in hypercholesterolemic mice
Busch, C. J., Hendrikx, T., Weismann, D., Jäckel, S., Walenbergh, S. M. A., Rendeiro, A. F., Weißer, J., Puhm, F., Hladik, A., Göderle, L., et al. (2016) · Hepatology · doi:10.1002/hep.28970 · Cited by 69 · see citing works
Self-citationNLRP3 inflammasome in cardiovascular diseases: an update
Mo, B., Ding, Y., & Ji, Q. (2025) · Frontiers in Immunology · doi:10.3389/fimmu.2025.1550226 · Cited by 67 · see citing works
Zimmerman, M. C., Clemens, D. L., Duryee, M. J., Sarmiento, C., Chiou, A., Hunter, C. D., Tian, J., Klassen, L. W., O’Dell, J. R., Thiele, G. M., et al. (2017) · Redox Biology · doi:10.1016/j.redox.2017.07.018 · Cited by 67 · see citing works
Oxidative Modification of Proteins: From Damage to Catalysis, Signaling, and Beyond
Demasi, M., Augusto, O., Bechara, E. J. H., Bicev, R. N., Cerqueira, F. M., da Cunha, F. M., Denicola, A., Gomes, F., Miyamoto, S., Netto, L. E. S., et al. (2021) · Antioxidants and Redox Signaling · doi:10.1089/ars.2020.8176 · Cited by 68 · see citing works
Oxidation-specific epitopes restrain bone formation
Ambrogini, E., Que, X., Wang, S., Yamaguchi, F., Weinstein, R. S., Tsimikas, S., Manolagas, S. C., Witztum, J. L., & Jilka, R. L. (2018) · Nature Communications · doi:10.1038/s41467-018-04047-5 · Cited by 64 · see citing works
Self-citationFunctional Role of B Cells in Atherosclerosis
Ma, S. D., Mußbacher, M., & Galkina, E. (2021) · Cells · doi:10.3390/cells10020270 · Cited by 64 · see citing works
Spickett, C. M., & Pitt, A. R. (2019) · Essays in Biochemistry · doi:10.1042/ebc20190058 · Cited by 63 · see citing works
REVISTA DA UNIVERSIDADE VALE DO RIO VERDE
Ferreira, F. S. (2014) · Revista da Universidade Vale do Rio Verde · doi:10.5892/ruvrd · Cited by 62 · see citing works
The why and how of adaptive immune responses in ischemic cardiovascular disease
Mallat, Z., & Binder, C. J. (2022) · Nature Cardiovascular Research · doi:10.1038/s44161-022-00049-1 · Cited by 61 · see citing works
Self-citationLacy, M., Atzler, D., Liu, R., de Winther, M. P. J., Weber, C., & Lutgens, E. (2018) · Pharmacology & Therapeutics · doi:10.1016/j.pharmthera.2018.08.012 · Cited by 61 · see citing works
The Emerging Role of B Lymphocytes in Cardiovascular Disease
Adamo, L., Resende, C. R., & Mann, D. L. (2020) · Annual Review of Immunology · doi:10.1146/annurev-immunol-042617-053104 · Cited by 60 · see citing works
Therapeutic Potential of Polyphenols-Loaded Polymeric Nanoparticles in Cardiovascular System
Pecháňová, O., Dayar, E., & Cebová, M. (2020) · Molecules · doi:10.3390/molecules25153322 · Cited by 63 · see citing works
Where the Action Is—Leukocyte Recruitment in Atherosclerosis
Mauersberger, C., Hinterdobler, J., Schunkert, H., Kessler, T., & Sager, H. B. (2022) · Frontiers in Cardiovascular Medicine · doi:10.3389/fcvm.2021.813984 · Cited by 59 · see citing works
Senders, M. L., Que, X., Cho, Y. S., Yeang, C., Groenen, H., Fay, F., Calcagno, C., Meerwaldt, A. E., Green, S., Miu, P., et al. (2018) · Journal of the American College of Cardiology · doi:10.1016/j.jacc.2017.11.036 · Cited by 58 · see citing works
Self-citationPrasad, A., Clopton, P., Ayers, C. R., Khera, A., de Lemos, J. A., Witztum, J. L., & Tsimikas, S. (2017) · Arteriosclerosis Thrombosis and Vascular Biology · doi:10.1161/atvbaha.117.309101 · Cited by 55 · see citing works
Self-citationNovel Antioxidant Properties of Doxycycline
Clemens, D. L., Duryee, M. J., Sarmiento, C., Chiou, A., McGowan, J. D., Hunter, C. D., Schlichte, S. L., Tian, J., Klassen, L. W., O’Dell, J. R., et al. (2018) · International Journal of Molecular Sciences · doi:10.3390/ijms19124078 · Cited by 54 · see citing works
Extracellular vesicles and redox modulation in aging
Borrás, C., Mas‐Bargues, C., Sanz‐Ros, J., Román-Domínguez, A., Gimeno-Mallench, L., Inglés, M., Gambini, J., & Viña, J. (2019) · Free Radical Biology and Medicine · doi:10.1016/j.freeradbiomed.2019.11.032 · Cited by 54 · see citing works
Tear-Based Ocular Wearable Biosensors for Human Health Monitoring
Arunima Rajan, S., Vishnu, J., & Shankar, B. (2024) · Biosensors · doi:10.3390/bios14100483 · Cited by 53 · see citing works
Targeting organ-specific mitochondrial dysfunction to improve biological aging
Madreiter‐Sokolowski, C. T., Hiden, U., Krstić, J., Panzitt, K., Wagner, M., Enzinger, C., Khalil, M., Abdellatif, M., Malle, E., Madl, T., et al. (2024) · Pharmacology & Therapeutics · doi:10.1016/j.pharmthera.2024.108710 · Cited by 54 · see citing works
Self-citationAndreadou, I., Daiber, A., Baxter, G. F., Brizzi, M. F., Lisa, F. D., Kaludercic, N., Lazou, A., Varga, Z. V., Zuurbier, C. J., Schulz, R., et al. (2021) · Free Radical Biology and Medicine · doi:10.1016/j.freeradbiomed.2021.02.012 · Cited by 52 · see citing works
Canonical and non-canonical roles of complement in atherosclerosis
Maffia, P., Mauro, C., Case, A. G., & Kemper, C. (2024) · Nature Reviews Cardiology · doi:10.1038/s41569-024-01016-y · Cited by 50 · see citing works
Lysosomes in the immunometabolic reprogramming of immune cells in atherosclerosis
Bonacina, F., Zhang, X., Manel, N., Yvan‐Charvet, L., Razani, B., & Norata, G. D. (2024) · Nature Reviews Cardiology · doi:10.1038/s41569-024-01072-4 · Cited by 50 · see citing works
Oxidative Stress and Its Biomarkers in Cardiovascular Diseases
Valaitienė, J., & Laučytė-Cibulskienė, A. (2024) · Artery Research · doi:10.1007/s44200-024-00062-8 · Cited by 49 · see citing works
Prohaska, T. A., Que, X., Diehl, C. J., Hendrikx, S., Chang, M. W., Jepsen, K., Glass, C. K., Benner, C. W., & Witztum, J. L. (2018) · The Journal of Immunology · doi:10.4049/jimmunol.1700568 · Cited by 49 · see citing works
Self-citationHaudum, C. W., Lindheim, L., Ascani, A., Trummer, C., Horvath, A., Münzker, J., & Obermayer-Pietsch, B. M. (2020) · Nutrients · doi:10.3390/nu12061622 · Cited by 48 · see citing works
- Authors
- Binder, C. J., Papac-Milicevic, N., & Witztum, J. L.
- Affiliations
- Austrian Academy of Sciences (AT)
- University of California San Diego (US)
- Corresponding author
- Binder, Christoph J.
- Venue
- Nature Reviews Immunology
- Published
- 2016-06-27
- Volume
- 16
- Issue
- 8
- Pages
- 485-497
- ISSN
- 1474-1733 (ISSN-L)
- 1474-1741
- PMC
- PMC7097710
- OpenAlex
- W2468517437
- Cited by
- 403
- References
- 152
- Citations by year
- 2026: 33 · 2025: 44 · 2024: 54 · 2023: 35 · 2022: 49 · 2021: 52 · 2020: 48 · 2019: 35 · 2018: 30 · 2017: 18 · 2016: 4 · 2014: 1
- FWCI
- 2.76
- Type
- journal article
- Language
- en
- Open access
- bronze
- doi.org
- Licence
- Locations
- Nature reviews. Immunology (publishedVersion)
- PubMed Central (publishedVersion)
- PubMed (publishedVersion)
- Funders
- Austrian Science Fund (SFB‐54)
- National Institutes of Health (HL055798)
- National Heart, Lung, and Blood Institute (P01HL055798, R01HL119828, R01HL086559)
- Topics
- Life Sciences › Immunology and Microbiology › Immunology › Immune Response and Inflammation
- Life Sciences › Immunology and Microbiology › Immunology › Atherosclerosis and Cardiovascular Diseases
- Life Sciences › Immunology and Microbiology › Immunology › Neutrophil, Myeloperoxidase and Oxidative Mechanisms
- Keywords
- oxidation-specific epitopes, lipid peroxidation, oxidative stress, damage-associated molecular patterns, innate immunity, pattern recognition receptors, chronic inflammation, atherosclerosis, age-related macular degeneration, tissue homeostasis, lipoprotein oxidation
- MeSH terms
- Animals, Epitopes, Disease Susceptibility, Homeostasis, Humans, Immunity, Cellular, Immunity, Innate, Oxidation-Reduction, Lipid Peroxidation, Oxidative Stress, Lipid Metabolism, Immunity, Humoral
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review