Annexin A1 and glucocorticoids as effectors of the resolution of inflammation

How do glucocorticoids influence stress responses? Integrating permissive, suppressive, stimulatory, and preparative actions

Sapolsky, R. M., Romero, L. M., & Munck, A. U. (2000) · Endocrine Reviews · doi:10.1210/edrv.21.1.0389 · Cited by 7,541

Antiinflammatory Action of Glucocorticoids — New Mechanisms for Old Drugs

Rhen, T., & Cidlowski, J. A. (2005) · New England Journal of Medicine · doi:10.1056/nejmra050541 · Cited by 3,149

Resolution of inflammation: the beginning programs the end

Serhan, C. N., & Savill, J. (2005) · Nature Immunology · doi:10.1038/ni1276 · Cited by 2,552

Annexins: linking Ca2+ signalling to membrane dynamics

Gerke, V., Creutz, C. E., & Moss, S. E. (2005) · Nature Reviews Molecular Cell Biology · doi:10.1038/nrm1661 · Cited by 1,412

Resolution of in flammation: state of the art, definitions and terms

Serhan, C. N., Brain, S. D., Buckley, C. D., Gilroy, D. W., Haslett, C., O'Neill, L. A. J., Perretti, M., Rossi, A. G., & Wallace, J. L. (2007) · The FASEB Journal · doi:10.1096/fj.06-7227rev · Cited by 1,045 · cited 1×

Promotion of Tissue Inflammation by the Immune Receptor Tim-3 Expressed on Innate Immune Cells

Anderson, A. C., Anderson, D. E., Bregoli, L., Hastings, W. D., Kassam, N., Lei, C., Chandwaskar, R., Kármán, J., Su, E. W., Hirashima, M., et al. (2007) · Science · doi:10.1126/science.1148536 · Cited by 703

Histone deacetylase 2–mediated deacetylation of the glucocorticoid receptor enables NF-κB suppression

Ito, K., Yamamura, S., Essilfie-Quaye, S., Cosio, B., Ito, M., Barnes, P. J., & Adcock, I. M. (2006) · The Journal of Experimental Medicine · doi:10.1084/jem.20050466 · Cited by 638

Glucocorticoids and the Th1/Th2 Balance

Elenkov, I. J. (2004) · Annals of the New York Academy of Sciences · doi:10.1196/annals.1321.010 · Cited by 618

Glucocorticoids promote a TH2 cytokine response by CD4+ T cells in vitro

Ramírez, F., Fowell, D. J., Puklavec, M. J., Simmonds, S. J., & Mason, D. (1996) · The Journal of Immunology · doi:10.4049/jimmunol.156.7.2406 · Cited by 483

The Lipoxin Receptor ALX: Potent Ligand-Specific and Stereoselective Actions in Vivo

Chiang, N., Serhan, C. N., Dahlén, S., Drazen, J. M., Hay, D. W. P., Rovati, G. E., Shimizu, T., Yokomizo, T., & Brink, C. (2006) · Pharmacological Reviews · doi:10.1124/pr.58.3.4 · Cited by 464

Cytokine-mediated regulation of CXCR4 expression in human neutrophils

Nagase, H., Miyamasu, M., Yamaguchi, M., Imanishi, M., Tsuno, N. H., Matsushima, K., Yamamoto, K., Morita, Y., & Hirai, K. (2002) · Journal of Leukocyte Biology · doi:10.1189/jlb.71.4.711 · Cited by 4,713

Immunogenic cell death in cancer and infectious disease

Galluzzi, L., Buqué, A., Kepp, O., Zitvogel, L., & Kroemer, G. (2017) · Nature Reviews Immunology · doi:10.1038/nri.2016.107 · Cited by 3,119

Nonresolving Inflammation

Nathan, C., & Ding, A. (2010) · Cell · doi:10.1016/j.cell.2010.02.029 · Cited by 2,183

The anti-inflammatory and immunosuppressive effects of glucocorticoids, recent developments and mechanistic insights

Coutinho, A. E., & Chapman, K. E. (2011) · Molecular and Cellular Endocrinology · doi:10.1016/j.mce.2010.04.005 · Cited by 1,815

Inflammation and its resolution in atherosclerosis: mediators and therapeutic opportunities

Bäck, M., Yurdagul, A., Tabas, I., Öörni, K., & Kovanen, P. T. (2019) · Nature Reviews Cardiology · doi:10.1038/s41569-019-0169-2 · Cited by 1,341

Polymeric Nanoparticles for Drug Delivery

Beach, M. A., Nayanathara, U., Gao, Y., Zhang, C., Xiong, Y., Wang, Y., & Such, G. K. (2024) · Chemical Reviews · doi:10.1021/acs.chemrev.3c00705 · Cited by 1,279

Macrophage death and defective inflammation resolution in atherosclerosis

Tabas, I. (2010) · Nature Reviews Immunology · doi:10.1038/nri2675 · Cited by 1,120

Phagocyte partnership during the onset and resolution of inflammation

Soehnlein, O., & Lindbom, L. (2010) · Nature Reviews Immunology · doi:10.1038/nri2779 · Cited by 1,054

Resolution of inflammation: a new therapeutic frontier

Fullerton, J. N., & Gilroy, D. W. (2016) · Nature Reviews Drug Discovery · doi:10.1038/nrd.2016.39 · Cited by 937

Specialized pro-resolving mediators: endogenous regulators of infection and inflammation

Basil, M. C., & Levy, B. D. (2015) · Nature reviews. Immunology · doi:10.1038/nri.2015.4 · Cited by 832

Resolvin D1 binds human phagocytes with evidence for proresolving receptors

Krishnamoorthy, S., Recchiuti, A., Chiang, N., Yacoubian, S., Lee, C., Yang, R., Petasis, N. A., & Serhan, C. N. (2010) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0907342107 · Cited by 752

Resolution of inflammation: an integrated view

Ortega‐Gómez, A., Perretti, M., & Soehnlein, O. (2013) · EMBO Molecular Medicine · doi:10.1002/emmm.201202382 · Cited by 776

Monocyte-macrophages and T cells in atherosclerosis

Tabas, I., & Lichtman, A. H. (2017) · Immunity · doi:10.1016/j.immuni.2017.09.008 · Cited by 646

Resolution of Inflammation: What Controls Its Onset?

Sugimoto, M. A., Sousa, L. P., Pinho, V., Perretti, M., & Teixeira, M. M. (2016) · Frontiers in Immunology · doi:10.3389/fimmu.2016.00160 · Cited by 638

Strategies to increase nitric oxide signalling in cardiovascular disease

Lundberg, J. O., Gladwin, M. T., & Weitzberg, E. (2015) · Nature Reviews Drug Discovery · doi:10.1038/nrd4623 · Cited by 576

Treating inflammation and infection in the 21st century: new hints from decoding resolution mediators and mechanisms

Serhan, C. N. (2017) · The FASEB Journal · doi:10.1096/fj.201601222r · Cited by 566

Lipid Mediators in the Resolution of InflammationPreprint

Serhan, C. N., Chiang, N., Dalli, J., & Levy, B. D. (2014) · Cold Spring Harbor Perspectives in Biology · doi:10.1101/cshperspect.a016311 · Cited by 568

Inflammation and its Resolution as Determinants of Acute Coronary Syndromes

Libby, P., Tabas, I. A., Fredman, G., & Fisher, E. A. A. (2014) · Circulation Research · doi:10.1161/circresaha.114.302699 · Cited by 531

Genetic programs expressed in resting and IL-4 alternatively activated mouse and human macrophages: similarities and differences

Martínez, F. O., Helming, L., Milde, R., Varin, A., Melgert, B. N., Draijer, C., Thomas, B., Fabbri, M., Crawshaw, A., Ho, L., et al. (2013) · Blood · doi:10.1182/blood-2012-06-436212 · Cited by 527

Influence of maternal thyroid hormones during gestation on fetal brain development

Moog, N. K., Entringer, S., Heim, C. C., Wadhwa, P. D., Kathmann, N., & Buß, C. (2015) · Neuroscience · doi:10.1016/j.neuroscience.2015.09.070 · Cited by 497

Resolvins, Specialized Proresolving Lipid Mediators, and Their Potential Roles in Metabolic Diseases

Spite, M., Clària, J., & Serhan, C. N. (2014) · Cell Metabolism · doi:10.1016/j.cmet.2013.10.006 · Cited by 464

Molecular Biology of Atherosclerosis

Hopkins, P. N. (2013) · Physiological Reviews · doi:10.1152/physrev.00004.2012 · Cited by 469

More friend than foe: the emerging role of neutrophils in tissue repair

Peiseler, M., & Kubes, P. (2019) · Journal of Clinical Investigation · doi:10.1172/jci124616 · Cited by 423

Annexin A1 and the Resolution of Inflammation: Modulation of Neutrophil Recruitment, Apoptosis, and Clearance

Sugimoto, M. A., Vago, J. P., Teixeira, M. M., & Sousa, L. P. (2016) · Journal of Immunology Research · doi:10.1155/2016/8239258 · Cited by 410

Novel Lipid Mediators Promote Resolution of Acute Inflammation

Spite, M. R., & Serhan, C. N. (2010) · Circulation Research · doi:10.1161/circresaha.110.223883 · Cited by 379

Targeted nanoparticles containing the proresolving peptide Ac2-26 protect against advanced atherosclerosis in hypercholesterolemic mice

Fredman, G., Kamaly, N., Spolitu, S., Milton, J., Ghorpade, D. S., Chiasson, R., Kuriakose, G., Perretti, M., Farokhzad, O. C., & Tabas, I. A. (2015) · Science Translational Medicine · doi:10.1126/scitranslmed.aaa1065 · Cited by 362

Annexin A1–containing extracellular vesicles and polymeric nanoparticles promote epithelial wound repair

Leoni, G., Neumann, P., Kamaly, N., Quirós, M., Nishio, H., Jones, H. R., Sumagin, R., Hilgarth, R., Alam, A. M., Fredman, G., et al. (2015) · Journal of Clinical Investigation · doi:10.1172/jci76693 · Cited by 362

Neutrophil clearance: when the party is over, clean-up begins

Bratton, D. L., & Henson, P. M. (2011) · Trends in Immunology · doi:10.1016/j.it.2011.04.009 · Cited by 378

Microglia Function in Alzheimer’s Disease

Solito, E., & Sastre, M. (2012) · Frontiers in Pharmacology · doi:10.3389/fphar.2012.00014 · Cited by 361

The five rs of glucocorticoid action during inflammation: Ready, reinforce, repress, resolve, and restore

Busillo, J. M., & Cidlowski, J. A. (2013) · Trends in Endocrinology & Metabolism · doi:10.1016/j.tem.2012.11.005 · Cited by 339

Acute Lung Injury: How Macrophages Orchestrate Resolution of Inflammation and Tissue Repair

Herold, S., Mayer, K., & Lohmeyer, J. (2011) · Frontiers in Immunology · doi:10.3389/fimmu.2011.00065 · Cited by 344

Structural elucidation and physiologic functions of specialized pro-resolving mediators and their receptors

Chiang, N., & Serhan, C. N. (2017) · Molecular Aspects of Medicine · doi:10.1016/j.mam.2017.03.005 · Cited by 338

Mechanisms and Consequences of Defective Efferocytosis in Atherosclerosis

Yurdagul, A., Doran, A. C., Cai, B., Fredman, G., & Tabas, I. A. (2018) · Frontiers in Cardiovascular Medicine · doi:10.3389/fcvm.2017.00086 · Cited by 300

Anti-Inflammatory Role of the Murine Formyl-Peptide Receptor 2: Ligand-Specific Effects on Leukocyte Responses and Experimental Inflammation

Dufton, N., Hannon, R., Brancaleone, V., Dalli, J., Patel, H., Gray, M., D’Acquisto, F., Buckingham, J. C., Perretti, M., & Flower, R. J. (2010) · The Journal of Immunology · doi:10.4049/jimmunol.0903526 · Cited by 298

Heterogeneity of human bone marrow and blood natural killer cells defined by single-cell transcriptome

Yang, C., Siebert, J., Burns, R., Gerbec, Z. J., Bonacci, B. B., Rymaszewski, A. L., Rau, M. J., Riese, M. J., Rao, S., Carlson, K.-S., et al. (2019) · Nature Communications · doi:10.1038/s41467-019-11947-7 · Cited by 306

Annexin A1, formyl peptide receptor, and NOX1 orchestrate epithelial repair

Leoni, G., Alam, A. M., Neumann, P.-A., Lambeth, J. D., Cheng, G., McCoy, J. W., Hilgarth, R., Kundu, K., Murthy, N., Kusters, D. H. M., et al. (2012) · Journal of Clinical Investigation · doi:10.1172/jci65831 · Cited by 303

New insights into the anti-inflammatory mechanisms of glucocorticoids: an emerging role for glucocorticoid-receptor-mediated transactivation

Vandevyver, S., Dejager, L., Tuckermann, J., & Libert, C. (2013) · Endocrinology · doi:10.1210/en.2012-2045 · Cited by 296

Microglia in Alzheimer’s disease: pathogenesis, mechanisms, and therapeutic potentials

Miao, J., Ma, H., Yang, Y., Liao, Y., Lin, C., Zheng, J., Yu, M., & Lan, J. (2023) · Frontiers in Aging Neuroscience · doi:10.3389/fnagi.2023.1201982 · Cited by 293

Resolvin D1 Receptor Stereoselectivity and Regulation of Inflammation and Proresolving MicroRNAs

Krishnamoorthy, S., Recchiuti, A., Chiang, N., Fredman, G., & Serhan, C. N. (2012) · The American Journal of Pathology · doi:10.1016/j.ajpath.2012.01.028 · Cited by 283

Novel Anti-Inflammatory-Pro-Resolving Mediators and Their Receptors

Serhan, C. N., Krishnamoorthy, S., Recchiuti, A., & Chiang, N. (2011) · Current Topics in Medicinal Chemistry · doi:10.2174/1568026611109060629 · Cited by 281

The role of non-resolving inflammation in atherosclerosis

Kasikara, C., Doran, A. C., Cai, B., & Tabas, I. (2018) · Journal of Clinical Investigation · doi:10.1172/jci97950 · Cited by 266

Resolvin D1 and Resolvin D2 Govern Local Inflammatory Tone in Obese Fat

Clària, J., Dalli, J., Yacoubian, S., Gao, F., & Serhan, C. N. (2012) · The Journal of Immunology · doi:10.4049/jimmunol.1201272 · Cited by 271

Key mechanisms governing resolution of lung inflammation

Robb, C. T., Regan, K., Dorward, D. A., & Rossi, A. G. (2016) · Seminars in Immunopathology · doi:10.1007/s00281-016-0560-6 · Cited by 273

MerTK cleavage limits proresolving mediator biosynthesis and exacerbates tissue inflammation

Cai, B., Thorp, E. B., Doran, A. C., Subramanian, M., Sansbury, B. E., Lin, C., Spite, M. R., Fredman, G., & Tabas, I. A. (2016) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1524292113 · Cited by 256

The multiple myeloma microenvironment is defined by an inflammatory stromal cell landscape

de Jong, M. M. E., Kellermayer, Z., Papazian, N., Tahri, S., Hofste op Bruinink, D., Hoogenboezem, R., Sanders, M. A., van de Woestijne, P. C., Bos, P. K., Khandanpour, C., et al. (2021) · Nature Immunology · doi:10.1038/s41590-021-00931-3 · Cited by 250

Mechanisms of Action of Topical Corticosteroids in Psoriasis

Uva, L., Miguel, D., Pinheiro, C., Antunes, J., Cruz, D., Ferreira, J. B., & Filipe, P. (2012) · International Journal of Endocrinology · doi:10.1155/2012/561018 · Cited by 257

Dexamethasone modulates immature neutrophils and interferon programming in severe COVID-19

Sinha, S., Rosin, N. L., Arora, R., Labit, E., Jaffer, A., Cao, L., Farias, R., Nguyen, A., de Almeida, L. G. N., Dufour, A., et al. (2021) · Nature Medicine · doi:10.1038/s41591-021-01576-3 · Cited by 254

Transient TLR Activation Restores Inflammatory Response and Ability To Control Pulmonary Bacterial Infection in Germfree Mice

Fagundes, C. T., Amaral, F. A., Vieira, A. T., Soares, A. C., Pinho, V., Nicoli, J. R., Vieira, L. Q., Teixeira, M. M., & Souza, D. G. (2012) · The Journal of Immunology · doi:10.4049/jimmunol.1101682 · Cited by 244

Damage-Associated Molecular Patterns Control Neutrophil Recruitment

Pittman, K., & Kubes, P. (2013) · Journal of Innate Immunity · doi:10.1159/000347132 · Cited by 256

Lipoxins: resolutionary road

MADERNA, P., & Godson, C. (2009) · British Journal of Pharmacology · doi:10.1111/j.1476-5381.2009.00386.x · Cited by 238

Hydrogen Sulfide: An Endogenous Mediator of Resolution of Inflammation and Injury

Wallace, J. L., Ferraz, J. G., & Muscará, M. N. (2011) · Antioxidants and Redox Signaling · doi:10.1089/ars.2011.4351 · Cited by 234

Inflammation and resolution in obesity

Soták, M., Clark, M., Suur, B. E., & Börgeson, E. (2024) · Nature Reviews Endocrinology · doi:10.1038/s41574-024-01047-y · Cited by 260

Resolution Pharmacology: Opportunities for Therapeutic Innovation in Inflammation

Perretti, M., Leroy, X., Bland, E. J., & Montero‐Melendez, T. (2015) · Trends in Pharmacological Sciences · doi:10.1016/j.tips.2015.07.007 · Cited by 233

Lipoxin A4 Attenuates Obesity-Induced Adipose Inflammation and Associated Liver and Kidney Disease

Börgeson, E., Johnson, A. M. F., Lee, Y. S., Till, A., Syed, G. H., Shah, S. T. A., Guiry, P. J., Dalli, J., Colas, R. A., Serhan, C. N., et al. (2015) · Cell Metabolism · doi:10.1016/j.cmet.2015.05.003 · Cited by 225

Targeted Interleukin-10 Nanotherapeutics Developed with a Microfluidic Chip Enhance Resolution of Inflammation in Advanced Atherosclerosis

Kamaly, N., Fredman, G., Fojas, J. J. R., Subramanian, M., Choi, W. I., Zepeda, K., Vilos, C., Yu, M., Gadde, S., Wu, J., et al. (2016) · ACS Nano · doi:10.1021/acsnano.6b01114 · Cited by 221

Resolution of inflammation: Mechanisms and opportunity for drug development

Alessandri, A. L., Sousa, L. P., Lucas, C. D., Rossi, A. G., Pinho, V., & Teixeira, M. M. (2013) · Pharmacology & Therapeutics · doi:10.1016/j.pharmthera.2013.04.006 · Cited by 219

Plasma membrane repair and cellular damage control: The annexin survival kit

Draeger, A., Monastyrskaya, K., & Babiychuk, E. B. (2011) · Biochemical Pharmacology · doi:10.1016/j.bcp.2010.12.027 · Cited by 217

Development and in vivo efficacy of targeted polymeric inflammation-resolving nanoparticles

Kamaly, N., Fredman, G., Subramanian, M., Gadde, S., Pešić, A., Cheung, L., Fayad, Z. A., Langer, R., Tabas, I. A., & Farokhzad, O. C. (2013) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1303377110 · Cited by 215

Alveolar macrophages in tissue homeostasis, inflammation, and infection: evolving concepts of therapeutic targeting

Malainou, C., Abdin, S. M., Lachmann, N., Matt, U., & Herold, S. (2023) · Journal of Clinical Investigation · doi:10.1172/jci170501 · Cited by 215

Annexin A1: A Central Player in the Anti-Inflammatory and Neuroprotective Role of Microglia

McArthur, S., Cristante, E., Paterno, M., Christian, H., Roncaroli, F., Gillies, G. E., & Solito, E. (2010) · The Journal of Immunology · doi:10.4049/jimmunol.1001095 · Cited by 213

A Proresolving Peptide Nanotherapy for Site‐Specific Treatment of Inflammatory Bowel Disease by Regulating Proinflammatory Microenvironment and Gut Microbiota

Li, C., Yang, Z., Cheng, J., Guo, J., Zhang, Q., Zhang, X., Ren, J., Wang, F., Huang, J., Hu, H., et al. (2019) · Advanced Science · doi:10.1002/advs.201900610 · Cited by 209

The Interactome of the Glucocorticoid Receptor and Its Influence on the Actions of Glucocorticoids in Combatting Inflammatory and Infectious Diseases

Πέττα, Ι., Dejager, L., Ballegeer, M., Lievens, S., Tavernier, J. H., Bosscher, K. D., & Libert, C. (2016) · Microbiology and Molecular Biology Reviews · doi:10.1128/mmbr.00064-15 · Cited by 212

More Than Suppression: Glucocorticoid Action on Monocytes and Macrophages

Ehrchen, J. M., Roth, J., & Barczyk‐Kahlert, K. (2019) · Frontiers in Immunology · doi:10.3389/fimmu.2019.02028 · Cited by 205

Annexin A1 drives macrophage skewing to accelerate muscle regeneration through AMPK activation

McArthur, S., Juban, G., Gobbetti, T., Desgeorges, T., Théret, M., Gondin, J., Toller-Kawahisa, J. E., Reutelingsperger, C. P. M., Chazaud, B., Perretti, M., et al. (2020) · Journal of Clinical Investigation · doi:10.1172/jci124635 · Cited by 209

Nanomedicines for the treatment of rheumatoid arthritis: State of art and potential therapeutic strategies

Wang, Q., Qin, X., Fang, J., & Sun, X. (2021) · Acta Pharmaceutica Sinica B · doi:10.1016/j.apsb.2021.03.013 · Cited by 201

Mechanisms of the anti‐inflammatory effects of glucocorticoids: genomic and nongenomic interference with MAPK signaling pathways

Ayroldi, E., Cannarile, L., Migliorati, G., Nocentini, G., Delfino, D. V., & Riccardi, C. (2012) · The FASEB Journal · doi:10.1096/fj.12-216382 · Cited by 207

Annexin A1 modulates natural and glucocorticoid-induced resolution of inflammation by enhancing neutrophil apoptosis

Vago, J. P., Nogueira, C. R. C., Tavares, L. P., Soriani, F. M., Lopes, F., Russo, R. C., Pinho, V., Teixeira, M. M., & Sousa, L. P. (2012) · Journal of Leukocyte Biology · doi:10.1189/jlb.0112008 · Cited by 192

Circulating myeloid-derived MMP8 in stress susceptibility and depression

Cathomas, F., Lin, H.-Y., Chan, K. L., Li, L., Parise, L. F., Alvarez, J., Durand-de Cuttoli, R., Aubry, A. V., Muhareb, S., Desland, F., et al. (2024) · Nature · doi:10.1038/s41586-023-07015-2 · Cited by 189

Estrogen protects the blood–brain barrier from inflammation-induced disruption and increased lymphocyte trafficking

Maggioli, E., McArthur, S., Mauro, C., Kieswich, J. E., Kusters, D. H. M., Reutelingsperger, C. P. M., Yaqoob, M. M., & Solito, E. (2015) · Brain Behavior and Immunity · doi:10.1016/j.bbi.2015.08.020 · Cited by 183

FPR2/ALX receptor expression and internalization are critical for lipoxin A 4 and annexin‐derived peptide‐stimulated phagocytosis

MADERNA, P., Cottell, D. C., Toivonen, T., Dufton, N., Dalli, J., Perretti, M., & Godson, C. (2010) · The FASEB Journal · doi:10.1096/fj.10-159913 · Cited by 182

Molecular mechanisms of peritoneal dissemination in gastric cancer

Kanda, M., & Kodera, Y. (2016) · World Journal of Gastroenterology · doi:10.3748/wjg.v22.i30.6829 · Cited by 181

The Role of Glucocorticoids in Inflammatory Diseases

Reichardt, S. D., Amouret, A., Muzzi, C., Vettorazzi, S., Tuckermann, J. P., Lühder, F., & Reichardt, H. M. (2021) · Cells · doi:10.3390/cells10112921 · Cited by 191

Inflammation Resolution: Implications for Atherosclerosis

Doran, A. C. (2022) · Circulation Research · doi:10.1161/circresaha.121.319822 · Cited by 181

Oxylipin biosynthesis reinforces cellular senescence and allows detection of senolysis

Wiley, C. D., Sharma, R., Davis, S. S., Lopez-Dominguez, J. A., Mitchell, K. P., Wiley, S., Alimirah, F., Kim, D. E., Payne, T., Rosko, A., et al. (2021) · Cell Metabolism · doi:10.1016/j.cmet.2021.03.008 · Cited by 173

Identification and Validation of Novel Cerebrospinal Fluid Biomarkers for Staging Early Alzheimer's Disease

Perrin, R. J., Craig‐Schapiro, R., Malone, J. P., Shah, A. R., Erdmann-Gilmore, P., Davis, A., Roe, C. M., Peskind, E. R., Li, G., Galasko, D. R., et al. (2011) · PLoS ONE · doi:10.1371/journal.pone.0016032 · Cited by 175

Resolvins: Anti-Inflammatory and Proresolving Mediators Derived from Omega-3 Polyunsaturated Fatty Acids

Zhang, M. J., & Spite, M. R. (2012) · Annual Review of Nutrition · doi:10.1146/annurev-nutr-071811-150726 · Cited by 171

Salivary biomarkers for the diagnosis and monitoring of neurological diseases

Farah, R., Haraty, H., Salame, Z., Fares, Y., Ojcius, D. M., & Sadier, N. S. (2018) · Biomedical Journal · doi:10.1016/j.bj.2018.03.004 · Cited by 175

Extracellular vesicles-mediated interaction within intestinal microenvironment in inflammatory bowel disease

Shen, Q., Huang, Z., Yao, J., & Jin, Y. (2021) · Journal of Advanced Research · doi:10.1016/j.jare.2021.07.002 · Cited by 163

Specialized proresolving mediator targets for RvE1 and RvD1 in peripheral blood and mechanisms of resolution

Fredman, G., & Serhan, C. N. (2011) · Biochemical Journal · doi:10.1042/bj20110327 · Cited by 162

Current Approaches for Combination Therapy of Cancer: The Role of Immunogenic Cell Death

Asadzadeh, Z., Safarzadeh, E., Safaei, S., Baradaran, A., Mohammadi, A., Hajiasgharzadeh, K., Derakhshani, A., Argentiero, A., Silvestris, N., & Baradaran, B. (2020) · Cancers · doi:10.3390/cancers12041047 · Cited by 158

Annexins—a family of proteins with distinctive tastes for cell signaling and membrane dynamics

Gerke, V., Gavins, F. N. E., Geisow, M. J., Grewal, T., Jaiswal, J. K., Nylandsted, J., & Rescher, U. (2024) · Nature Communications · doi:10.1038/s41467-024-45954-0 · Cited by 157

Anti-Inflammatory and Cytoprotective Actions of Hydrogen Sulfide: Translation to Therapeutics

Wallace, J. L., Blackler, R. W., Chan, M. V., Da Silva, G. J., Elsheikh, W., Flannigan, K. L., Gamaniek, I., Manko, A., Wang, L., Motta, J.-P., et al. (2015) · Antioxidants & Redox Signaling · doi:10.1089/ars.2014.5901 · Cited by 156

Exploiting the Annexin A1 pathway for the development of novel anti‐inflammatory therapeutics

Perretti, M., & Dalli, J. (2009) · British Journal of Pharmacology · doi:10.1111/j.1476-5381.2009.00483.x · Cited by 159

Redefining the perioperative stress response: a narrative review

Manou‐Stathopoulou, V., Korbonits, M., & Ackland, G. L. (2019) · British Journal of Anaesthesia · doi:10.1016/j.bja.2019.08.011 · Cited by 164

Annexin 1 Induced by Anti-Inflammatory Drugs Binds to NF-κB and Inhibits Its Activation: Anticancer Effects In vitro and In vivo

Zhang, Z., Huang, L., Zhao, W., & Rigas, B. (2010) · Cancer Research · doi:10.1158/0008-5472.can-09-4204 · Cited by 150

Intranasal Administration of Extracellular Vesicles Derived from Human Teeth Stem Cells Improves Motor Symptoms and Normalizes Tyrosine Hydroxylase Expression in the Substantia Nigra and Striatum of the 6-Hydroxydopamine-Treated Rats

Narbute, K., Piļipenko, V., Pupure, J., Dzirkale, Z., Jonavičė, U., Tunaitis, V., Kriaučiūnaitė, K., Jarmalavičiūtė, A., Jansone, B., Kluša, V., et al. (2019) · Stem Cells Translational Medicine · doi:10.1002/sctm.18-0162 · Cited by 150

Enzymatic Shaving of the Tegument Surface of Live Schistosomes for Proteomic Analysis: A Rational Approach to Select Vaccine Candidates

Castro‐Borges, W., Dowle, A., Curwen, R. S., THOMAS‐OATES, J. E., & Wilson, R. A. (2011) · PLoS neglected tropical diseases · doi:10.1371/journal.pntd.0000993 · Cited by 149

Regulation of Circulating Neutrophil Numbers under Homeostasis and in Disease

Strydom, N., & Rankin, S. M. (2013) · Journal of Innate Immunity · doi:10.1159/000350282 · Cited by 149

An annexin A1–FPR1 interaction contributes to necroptosis of keratinocytes in severe cutaneous adverse drug reactions

Saito, N., Qiao, H., Yanagi, T., Shinkuma, S., Nishimura, K., Suto, A., Fujita, Y., Suzuki, S., Nomura, T., Nakamura, H., et al. (2014) · Science Translational Medicine · doi:10.1126/scitranslmed.3008227 · Cited by 148

Medicinal plants with anti-inflammatory activities

Μaione, F., Russo, R., Khan, H. Z., & Mascolo, N. (2015) · Natural Product Research · doi:10.1080/14786419.2015.1062761 · Cited by 147

Fighting the Fire: Mechanisms of Inflammatory Gene Regulation by the Glucocorticoid Receptor

Escoter-Torres, L., Caratti, G., Mechtidou, A., Tuckermann, J. P., Uhlenhaut, N. H., & Vettorazzi, S. (2019) · Frontiers in Immunology · doi:10.3389/fimmu.2019.01859 · Cited by 156

Application of Label-Free Absolute Quantitative Proteomics in Human Gingival Crevicular Fluid by LC/MSE (Gingival Exudatome)

Bostancı, N., Heywood, W., Mills, K. A., Parkar, M. H., Nibali, L., & Donos, N. (2010) · Journal of Proteome Research · doi:10.1021/pr900941z · Cited by 145

Circadian Clocks, Stress, and Immunity

Dumbell, R., Matveeva, O., & Oster, H. (2016) · Frontiers in Endocrinology · doi:10.3389/fendo.2016.00037 · Cited by 150

Stress-induced cellular responses in immunogenic cell death: Implications for cancer immunotherapy

Radogna, F., & Diederich, M. F. (2018) · Biochemical Pharmacology · doi:10.1016/j.bcp.2018.02.006 · Cited by 146

Immune Effects of Corticosteroids in Sepsis

Heming, N., Sivanandamoorthy, S., Meng, P., Bounab, R., & Annane, D. (2018) · Frontiers in Immunology · doi:10.3389/fimmu.2018.01736 · Cited by 148

Failure of Respiratory Defenses in the Pathogenesis of Bacterial Pneumonia of Cattle

Caswell, J. (2013) · Veterinary Pathology · doi:10.1177/0300985813502821 · Cited by 158

Plasmin and plasminogen induce macrophage reprogramming and regulate key steps of inflammation resolution via annexin A1

Sugimoto, M. A., Ribeiro, A. L. C., Costa, B. R. C., Vago, J. P., Lima, K. M., Carneiro, F. S., Ortiz, M. M. O., Negreiros-Lima, G. L., Carmo, A. A. F., Rocha, R. M., et al. (2017) · Blood · doi:10.1182/blood-2016-09-742825 · Cited by 143

The annexins: spatial and temporal coordination of signaling events during cellular stress

Monastyrskaya, K., Babiychuk, E. B., & Draeger, A. (2009) · Cellular and Molecular Life Sciences · doi:10.1007/s00018-009-0027-1 · Cited by 139

The multiple facets of glucocorticoid action in rheumatoid arthritis

Baschant, U., Lane, N. E., & Tuckermann, J. P. (2012) · Nature Reviews Rheumatology · doi:10.1038/nrrheum.2012.166 · Cited by 140

Intermittent glucocorticoid steroid dosing enhances muscle repair without eliciting muscle atrophy

Quattrocelli, M., Barefield, D. Y., Warner, J. L., Vo, A. H., Hadhazy, M., Earley, J. U., Demonbreun, A. R., & McNally, E. M. (2017) · Journal of Clinical Investigation · doi:10.1172/jci91445 · Cited by 143

Annexin‐A1: a pivotal regulator of the innate and adaptive immune systems

D’Acquisto, F., Perretti, M., & Flower, R. J. (2008) · British Journal of Pharmacology · doi:10.1038/bjp.2008.252 · Cited by 194

[Annexin-1: 2nd messanger of the anti-inflammatory actions of glucocorticoids].

Castro‐Caldas, M. (2006) · PubMed · Cited by 4

Overview of the Role of Annexin 1 in the Innate and Adaptive Immune Response

D’Acquisto, F., & Perretti, M. (2008) · Immunology Endocrine & Metabolic Agents - Medicinal Chemistry · doi:10.2174/187152208785748313

Annexin-1 regulates inflammatory response via glucocorticoid-induced genes

Yang, Y. H., Rao, Z., Aeberli, D., Liu, J., Leech, M. T., Dacumos, A., Xue, J., & Morand, E. F. (2009)

The annexin-1 knockout mouse: what it tells us about the inflammatory response.

Roviezzo, F., Getting, S. J., Paul‐Clark, M. J., Yona, S., Gavins, F. N. E., Perretti, M., Hannon, R., Croxtall, J. D., Buckingham, J. C., & Flower, R. J. (2002) · PubMed · Cited by 82