Potential Roles of SNX17, Rab11, and Rab5 in LDLR Recycling

Regulated portals of entry into the cell

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Endosome maturation

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Lysosomes: fusion and function

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Endocytic recycling

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Rab Conversion as a Mechanism of Progression from Early to Late Endosomes

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Pathways and mechanisms of endocytic recycling

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EEA1 links PI(3)K function to Rab5 regulation of endosome fusion

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Distinct Membrane Domains on Endosomes in the Recycling Pathway Visualized by Multicolor Imaging of Rab4, Rab5, and Rab11

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Statin Safety and Associated Adverse Events: A Scientific Statement From the American Heart Association

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The PX domains of p47phox and p40phox bind to lipid products of PI(3)K

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A FAM21-Containing WASH Complex Regulates Retromer-Dependent Sorting

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The RAB25 small GTPase determines aggressiveness of ovarian and breast cancers

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Ligands for clathrin-mediated endocytosis are differentially sorted into distinct populations of early endosomes

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Receptor-mediated endocytosis: insights from the lipoprotein receptor system

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SNX27 mediates retromer tubule entry and endosome-to-plasma membrane trafficking of signalling receptors

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Acid-dependent ligand dissociation and recycling of LDL receptor mediated by growth factor homology region

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Endosomal sorting and signalling: an emerging role for sorting nexins

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Membrane traffic in the secretory pathway

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Rab11 in Recycling Endosomes Regulates the Sorting and Basolateral Transport of E-Cadherin

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Sorting out the cellular functions of sorting nexins

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Rab5 is necessary for the biogenesis of the endolysosomal system in vivo

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The enigmatic endosome—sorting the ins and outs of endocytic trafficking

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Retriever is a multiprotein complex for retromer-independent endosomal cargo recycling

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Exorcising the Exocyst Complex

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Phox domain interaction with PtdIns(3)P targets the Vam7 t-SNARE to vacuole membranes

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An actin-dependent mechanism for long-range vesicle transport

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Orchestration of cell surface proteins by Rab11

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An alternative mitophagy pathway mediated by Rab9 protects the heart against ischemia

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SNX27 mediates PDZ-directed sorting from endosomes to the plasma membrane

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Sec15 Is an Effector for the Rab11 GTPase in Mammalian Cells

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COMMD1 is linked to the WASH complex and regulates endosomal trafficking of the copper transporter ATP7A

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A loss-of-function screen reveals SNX5 and SNX6 as potential components of the mammalian retromer

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SNX4 coordinates endosomal sorting of TfnR with dynein-mediated transport into the endocytic recycling compartment

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Retromer and sorting nexins in endosomal sorting

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Molecular control of Rab activity by GEFs, GAPs and GDI

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Rab11, a small GTPase associated with both constitutive and regulated secretory pathways in PC12 cells

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Evidence that the rab5 effector APPL1 mediates APP-βCTF-induced dysfunction of endosomes in Down syndrome and Alzheimer’s disease

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Neuropilin-1 promotes VEGFR-2 trafficking through Rab11 vesicles thereby specifying signal output

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SNX17 protects integrins from degradation by sorting between lysosomal and recycling pathways

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CCC- and WASH-mediated endosomal sorting of LDLR is required for normal clearance of circulating LDL

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SNX9 Regulates Dynamin Assembly and Is Required for Efficient Clathrin-mediated Endocytosis

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TFEB regulates lysosomal positioning by modulating TMEM55B expression and JIP4 recruitment to lysosomes

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Exercise-induced circulating extracellular vesicles protect against cardiac ischemia–reperfusion injury

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Rab Family of GTPases

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A unique PDZ domain and arrestin-like fold interaction reveals mechanistic details of endocytic recycling by SNX27-retromer

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Dynein is required for receptor sorting and the morphogenesis of early endosomes

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Phosphatidylinositol-(4,5)-bisphosphate regulates clathrin-coated pit initiation, stabilization, and size

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SNX–BAR proteins in phosphoinositide-mediated, tubular-based endosomal sorting

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SNX–BAR‐Mediated Endosome Tubulation is Co‐ordinated with Endosome Maturation

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Endosomal retrieval of cargo: Retromer is not alone

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A molecular code for endosomal recycling of phosphorylated cargos by the SNX27–retromer complex

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Adaptor Protein Sorting Nexin 17 Regulates Amyloid Precursor Protein Trafficking and Processing in the Early Endosomes

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A Rab10-Dependent Mechanism for Polarized Basement Membrane Secretion during Organ Morphogenesis

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Sorting nexin 17 facilitates LRP recycling in the early endosome

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Reversible phosphorylation‐‐dephosphorylation determines the localization of rab4 during the cell cycle.

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Endosome Acidification and the Pathways of Receptor-Mediated Endocytosis

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Structural basis for VPS34 kinase activation by Rab1 and Rab5 on membranes

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The PX‐domain protein SNX17 interacts with members of the LDL receptor family and modulates endocytosis of the LDL receptor

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PIKfyve activity regulates reformation of terminal storage lysosomes from endolysosomes

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The Phosphoinositide-3-phosphatase MTMR2 Associates with MTMR13, a Membrane-associated Pseudophosphatase Also Mutated in Type 4B Charcot-Marie-Tooth Disease

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The COMMD Family Regulates Plasma LDL Levels and Attenuates Atherosclerosis Through Stabilizing the CCC Complex in Endosomal LDLR Trafficking

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TBC1D15/RAB7-regulated mitochondria-lysosome interaction confers cardioprotection against acute myocardial infarction-induced cardiac injury

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Modulation of Cellular Cholesterol Transport and Homeostasis by Rab11

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Phox homology band 4.1/ezrin/radixin/moesin-like proteins function as molecular scaffolds that interact with cargo receptors and Ras GTPases

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Endosomal PI(3)P regulation by the COMMD/CCDC22/CCDC93 (CCC) complex controls membrane protein recycling

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Alternative Mitophagy Protects the Heart Against Obesity-Associated Cardiomyopathy

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Rab10 regulates tubular endosome formation through KIF13A and KIF13B motors

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Distinct Pathways for the Trafficking of Angiotensin II and Adrenergic Receptors from the Endoplasmic Reticulum to the Cell Surface

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Rab11 activity and PtdIns(3)P turnover removes recycling cargo from endosomes

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Rab7 Is Functionally Required for Selective Cargo Sorting at the Early Endosome

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Five common gene variants identify elevated genetic risk for coronary heart disease

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Statins and its hepatic effects: Newer data, implications, and changing recommendations

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Single-cell RNA-seq and bulk-seq identify RAB17 as a potential regulator of angiogenesis by human dermal microvascular endothelial cells in diabetic foot ulcers

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PI(3,5)P2 controls endosomal branched actin dynamics by regulating cortactin–actin interactions

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Sorting Motifs in the Intracellular Domain of the Low Density Lipoprotein Receptor Interact with a Novel Domain of Sorting Nexin-17

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Rab5-mediated endosome formation is regulated at the trans-Golgi network

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Intracellular Trafficking Network of Protein Nanocapsules: Endocytosis, Exocytosis and Autophagy

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Identification and Characterization of SNX15, a Novel Sorting Nexin Involved in Protein Trafficking

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Molecular Analysis of Mouse Rab11b: A New Type of Mammalian YPT/Rab Protein

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Munc13-4 Is a Rab11-binding Protein That Regulates Rab11-positive Vesicle Trafficking and Docking at the Plasma Membrane

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SNX18 shares a redundant role with SNX9 and modulates endocytic trafficking at the plasma membrane

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Internalized Pseudomonas Exotoxin A can Exploit Multiple Pathways to Reach the Endoplasmic Reticulum

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Rab11 regulates the recycling and lysosome targeting of β2-adrenergic receptors

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Sorting Nexin 10 Mediates Metabolic Reprogramming of Macrophages in Atherosclerosis Through the Lyn-Dependent TFEB Signaling Pathway

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Endosome-to-Plasma Membrane Recycling of VEGFR2 Receptor Tyrosine Kinase Regulates Endothelial Function and Blood Vessel Formation

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The Rab5 effector FERRY links early endosomes with mRNA localization

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Three mechanisms control E-cadherin localization to the zonula adherens

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SEC16A is a RAB10 effector required for insulin-stimulated GLUT4 trafficking in adipocytes

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Low-Density Lipoprotein Internalization, Degradation and Receptor Recycling Along Membrane Contact Sites

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SNX27-FERM-SNX1 complex structure rationalizes divergent trafficking pathways by SNX17 and SNX27

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Regulation of Liver Metabolism by the Endosomal GTPase Rab5

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The emerging role of sorting nexins in cardiovascular diseases

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Abnormal Rab11‐Rab8‐vesicles cluster in enterocytes of patients with microvillus inclusion disease

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The Phox Homology (PX) Domain

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Safety and Tolerability of PCSK9 Inhibitors: Current Insights

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A Sorting Nexin 17‐Binding Domain Within the LRP1 Cytoplasmic Tail Mediates Receptor Recycling Through the Basolateral Sorting Endosome

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PCSK9 Promotes LDLR Degradation by Preventing SNX17-Mediated LDLR Recycling

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Rab8 Regulates ABCA1 Cell Surface Expression and Facilitates Cholesterol Efflux in Primary Human Macrophages

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Sorting nexin 17 regulates ApoER2 recycling and reelin signaling

Sotelo, P., Farfán, P., Benitez, M. L., Bu, G., & Marzolo, M.-P. (2014) · PLoS ONE · doi:10.1371/journal.pone.0093672 · Cited by 47

SNX13 reduction mediates heart failure through degradative sorting of apoptosis repressor with caspase recruitment domain

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A New Member of the Sorting Nexin Family Interacts with the C-Terminus of P-Selectin

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The structure of apolipoprotein B100 from human low-density lipoprotein

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Novel role of sorting nexin 5 in renal D 1 dopamine receptor trafficking and function: implications for hypertension

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Sorting nexin-4 regulates β-amyloid production by modulating β-site-activating cleavage enzyme-1

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The fungal RABOME: RAB GTPases acting in the endocytic and exocytic pathways of Aspergillus nidulans (with excursions to other filamentous fungi)

Pinar, M., & Peñalva, M. A. (2021) · Molecular Microbiology · doi:10.1111/mmi.14716 · Cited by 40

Reggie-1/Flotillin-2 regulates integrin trafficking and focal adhesion turnover via Rab11a

Hülsbusch, N., Solis, G. P., Katanaev, V. L., & Stuermer, C. A. O. (2015) · European Journal of Cell Biology · doi:10.1016/j.ejcb.2015.07.003 · Cited by 35

Epigenome-wide analysis of DNA methylation and coronary heart disease: a nested case-control study

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Targeting Rab7‐Rilp Mediated Microlipophagy Alleviates Lipid Toxicity in Diabetic Cardiomyopathy

Ke, J., Pan, J., Lin, H., Huang, S., Zhang, J., Wang, C., Chang, A. C. Y., & Gu, J. F. (2024) · Advanced Science · doi:10.1002/advs.202401676 · Cited by 35

Functional characterization of retromer in GLUT4 storage vesicle formation and adipocyte differentiation

Yang, Z., Hong, L. K., Follett, J., Wabitsch, M., Hamilton, N., Collins, B. M., Bugarc̀ić, A., & Teasdale, R. D. (2015) · The FASEB Journal · doi:10.1096/fj.15-274704 · Cited by 34

MicroRNA-101 Inhibits Rat Cardiac Hypertrophy by Targeting Rab1a

Wei, L., Yuan, M., Zhou, R., Bai, Q., Zhang, W., Zhang, M., Huang, Y., & Shi, L. (2015) · Journal of Cardiovascular Pharmacology · doi:10.1097/fjc.0000000000000203 · Cited by 33

Tyrosine phosphorylation of Rab7 by Src kinase

Lin, X., Zhang, J., Chen, L., Chen, Y., Xu, X., Hong, W., & Wang, T. (2017) · Cellular Signalling · doi:10.1016/j.cellsig.2017.03.006 · Cited by 33

Patient adherence, compliance, and perspectives on evolocumab for the management of resistant hypercholesterolemia

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Combined deficiency of RAB32 and RAB38 in the mouse mimics Hermansky-Pudlak syndrome and critically impairs thrombosis

Aguilar, A., Weber, J., Boscher, J., Freund, M., Ziessel, C., Eckly, A. E., Magnenat, S., Bourdon, C., Hechler, B., Mangin, P., et al. (2019) · Blood Advances · doi:10.1182/bloodadvances.2019031286 · Cited by 33

Sorting nexin 3 induces heart failure via promoting retromer-dependent nuclear trafficking of STAT3

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Structural basis of mRNA binding by the human FERRY Rab5 effector complex

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Emerging Role of Retromer in Modulating Pathogen Growth

Elwell, C. A., & Engel, J. N. (2018) · Trends in Microbiology · doi:10.1016/j.tim.2018.04.001 · Cited by 31

Involvement of Rab9 and Rab11 in the intracellular trafficking of TRPC6

Cayouette, S., Bousquet, S. M., Francoeur, N. J., Dupré, É., Monet, M., Gagnon, H., Guedri, Y., Lavoie, C. L., & Boulay, G. (2010) · Biochimica et Biophysica Acta (BBA) - Molecular Cell Research · doi:10.1016/j.bbamcr.2010.03.010 · Cited by 30

Role of SNX16 in the Dynamics of Tubulo-Cisternal Membrane Domains of Late Endosomes

Brankatschk, B., Pons, V., Parton, R. G., & Gruenberg, J. E. (2011) · PLoS ONE · doi:10.1371/journal.pone.0021771 · Cited by 30

Genetic associations with carotid intima-media thickness link to atherosclerosis with sex-specific effects in sub-Saharan Africans

Boua, P. R., Brandenburg, J., Choudhury, A., Sorgho, H., Nonterah, E. A., Agongo, G., Asiki, G., Micklesfield, L. K., Choma, S., Gómez-Olivé, F. X., et al. (2022) · Nature Communications · doi:10.1038/s41467-022-28276-x · Cited by 29

Genomic organization of the MTM1 gene implicated in X-linked myotubular myopathy

Laporte, J., Guiraud-Chaumeil, C., Tanner, S. M., Blondeau, F., Hu, L., Vicaire, S., Liechti‐Gallati, S., & Mandel, J. (1998) · European Journal of Human Genetics · doi:10.1038/sj.ejhg.5200189 · Cited by 28

Efficacy and tolerability of ezetimibe 10 mg/day coadministered with statins in patients with primary hypercholesterolemia who do not achieve target LDL-C while on statin monotherapy: A Canadian, multicentre, prospective study – the Ezetrol® Add-On Study

Bissonnette, S., Habib, R., Sampalis, F. S., Boukas, S., & Sampalis, J. S. (2006) · Canadian Journal of Cardiology · doi:10.1016/s0828-282x(06)70319-1 · Cited by 27

Identification of autophagic target RAB13 with small‐molecule inhibitor in low‐grade glioma via integrated multi‐omics approaches coupled with virtual screening of traditional Chinese medicine databases

Su, W. C., Liao, M., Tan, H., Chen, Y., Zhao, R., Jin, W., Zhu, S., Zhang, Y., Li, H., & Liu, B. (2021) · Cell Proliferation · doi:10.1111/cpr.13135 · Cited by 27

Proximity labelling identifies pro-migratory endocytic recycling cargo and machinery of the Rab4 and Rab11 families

Wilson, B. J., Flett, C., Gemperle, J., Lawless, C., Hartshorn, M., Hinde, E., Harrison, T. S., Chastney, M. R., Taylor, S., Allen, J., et al. (2023) · Journal of Cell Science · doi:10.1242/jcs.260468 · Cited by 27

Mechanism and regulation of cargo entry into the Commander endosomal recycling pathway

Butkovič, R., Walker, A. P., Healy, M. D., McNally, K. E., Liu, M., Veenendaal, T., Kato, K., Liv, N., Klumperman, J., Collins, B. M., et al. (2024) · Nature Communications · doi:10.1038/s41467-024-50971-0 · Cited by 26

Structural basis for Retriever-SNX17 assembly and endosomal sorting

Singla, A., Boesch, D. J., Fung, H. Y. J., Ngoka, C., Enriquez, A. S., Song, R., Kramer, D. A., Han, Y., Banarer, E., Lemoff, A., et al. (2024) · Nature Communications · doi:10.1038/s41467-024-54583-6 · Cited by 23

KIF13A—A Key Regulator of Recycling Endosome Dynamics

Thankachan, J. M., & Setty, S. R. G. (2022) · Frontiers in Cell and Developmental Biology · doi:10.3389/fcell.2022.877532 · Cited by 23

The small GTPase RAB10 regulates endosomal recycling of the LDL receptor and transferrin receptor in hepatocytes

Khan, T. G., Ginsburg, D., & Emmer, B. T. (2022) · Journal of Lipid Research · doi:10.1016/j.jlr.2022.100248 · Cited by 21

Rab11-FIP1A regulates early trafficking into the recycling endosomes

Schafer, J. C., McRae, R. E., Manning, E. H., Lapierre, L. A., & Goldenring, J. R. (2016) · Experimental Cell Research · doi:10.1016/j.yexcr.2016.01.003 · Cited by 21

Sorting Nexin 11 Regulates Lysosomal Degradation of Plasma Membrane TRPV3

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Essential and selective role of SNX12 in transport of endocytic and retrograde cargo

Priya, A., Sugatha, J., Parveen, S., Lacas‐Gervais, S., Raj, P., Gilleron, J., & Datta, S. (2017) · Journal of Cell Science · doi:10.1242/jcs.201905 · Cited by 21

Rab27a Regulates Human Perivascular Adipose Progenitor Cell Differentiation

Boucher, J. M., Robich, M. P., Scott, S. S., Yang, X., Ryzhova, L., Turner, J. E., Pinz, I. M., & Liaw, L. (2018) · Cardiovascular Drugs and Therapy · doi:10.1007/s10557-018-6813-y · Cited by 21

SNX17 (Sorting Nexin 17) Mediates Atrial Fibrillation Onset Through Endocytic Trafficking of the Kv1.5 (Potassium Voltage-Gated Channel Subfamily A Member 5) Channel

Li, G., Wang, S., Zhang, F., Xiong, K., Huang, J., Zhao, T., Shi, D., Lv, F., Li, L., Liang, D., et al. (2019) · Circulation Arrhythmia and Electrophysiology · doi:10.1161/circep.118.007097 · Cited by 20

Low-density lipoprotein cholesterol lowering therapy for the secondary prevention of atherosclerotic cardiovascular disease

Patel, P. N., & Giugliano, R. P. (2020) · Global Cardiology Science and Practice · doi:10.21542/gcsp.2020.39 · Cited by 19

Rab5 and Rab11 maintain hematopoietic homeostasis by restricting multiple signaling pathways in Drosophila

Yu, S., Luo, F., & Jin, L. H. (2021) · eLife · doi:10.7554/elife.60870 · Cited by 19

Phosphatidylinositol-(4,5)-Bisphosphate Regulates Plasma Cholesterol Through LDL (Low-Density Lipoprotein) Receptor Lysosomal Degradation

Qin, Y., Ting, F., Kim, M. J., Strelnikov, J., Harmon, J., Gao, F., Dose, A., Teng, B.-B., Alipour, M. A., Yao, Z., et al. (2020) · Arteriosclerosis, Thrombosis, and Vascular Biology · doi:10.1161/atvbaha.120.314033 · Cited by 18

Involvement of Rab28 in NF-κB Nuclear Transport in Endothelial Cells

Jiang, J., Qi, Y., Zhang, P., Gu, W.-T., Yan, Z., Shen, B., Yao, Q., Kong, H., Chien, S., & Jiang, Z. (2013) · PLoS ONE · doi:10.1371/journal.pone.0056076 · Cited by 18

Up-regulation of Cholesterol Absorption Is a Mechanism for Cholecystokinin-induced Hypercholesterolemia

Zhou, L., Yang, H., Okoro, E. U., & Guo, Z. (2014) · Journal of Biological Chemistry · doi:10.1074/jbc.m113.534388 · Cited by 18

SNX17 produces anti-arrhythmic effects by preserving functional SERCA2a protein in myocardial infarction

Zhao, D., Li, X., Liang, H., Zheng, N., Pan, Z., Zhou, Y., Liu, X., Qian, M. D., Xu, B., Zhang, Y., et al. (2018) · International Journal of Cardiology · doi:10.1016/j.ijcard.2018.07.025 · Cited by 18

Increased AT1 receptor expression mediates vasoconstriction leading to hypertension in Snx1−/− mice

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MiRNA-575 suppresses angiogenesis by targeting Rab5-MEK-ERK pathway in endothelial cells

Zhao, X., Yi, Y., Meng, C., & Fang, N. (2018) · Bioscience Reports · doi:10.1042/bsr20181218 · Cited by 17

Cargo-Specific Role for Retriever Subunit VPS26C in Hepatocyte Lipoprotein Receptor Recycling to Control Postprandial Triglyceride-Rich Lipoproteins

Vos, D. Y., Wijers, M., Smit, M., Huijkman, N., Kloosterhuis, N. J., Wolters, J. C., Tissink, J. J., Pronk, A. C. M., Kooijman, S., Rensen, P. C. N., et al. (2023) · Arteriosclerosis, Thrombosis, and Vascular Biology · doi:10.1161/atvbaha.122.318169 · Cited by 16

Rab11 is required for cell adhesion, maintenance of cell shape and actin-cytoskeleton organization during Drosophila wing development

Bhuin, T., & Roy, J. K. (2011) · The International Journal of Developmental Biology · doi:10.1387/ijdb.103149tb · Cited by 16

The Expression of Neuronal Sorting Nexin 8 (SNX8) Exacerbates Abnormal Cholesterol Levels

Muirhead, G., & Dev, K. K. (2013) · Journal of Molecular Neuroscience · doi:10.1007/s12031-013-0209-z · Cited by 16

Rab27a deletion impairs the therapeutic potential of endothelial progenitor cells for myocardial infarction

Zhou, W., Zheng, X., Cheng, C., Guo, G., Zhong, Y., Liu, W., Liu, K., Chen, Y., Liu, S., & Liu, S. (2020) · Molecular and Cellular Biochemistry · doi:10.1007/s11010-020-03945-x · Cited by 16

Expression analysis of Rab11 during zebrafish embryonic development

Zhang, H., Gao, Y., Qian, P., Dong, Z., Hao, W., Liu, D., & Duan, X. (2019) · BMC Developmental Biology · doi:10.1186/s12861-019-0207-7 · Cited by 15

Selective cargo and membrane recognition by SNX17 regulates its interaction with Retriever

Martín-González, A., Méndez-Guzmán, I., Zabala-Zearreta, M., Quintanilla, A., García-López, A., Martínez-Lombardía, E., Albesa-Jové, D., Acosta, J. C., & Lucas, M. (2025) · EMBO Reports · doi:10.1038/s44319-024-00340-1 · Cited by 15

Gentisic acid prevents the development of atherosclerotic lesions by inhibiting SNX10-mediated stabilization of LRP6

Chen, T., Wang, Y., Yang, J., Ni, J., You, K., Li, X., Song, Y., Wang, X., Li, J., Shen, X., et al. (2024) · Pharmacological Research · doi:10.1016/j.phrs.2024.107516 · Cited by 14

SNX8: A candidate gene for 7p22 cardiac malformations including tetralogy of fallot

Vanzo, R. J., Martin, M. M., Sdano, M. R., Teta, K., Aggarwal, V. S., & South, S. T. (2013) · American Journal of Medical Genetics Part A · doi:10.1002/ajmg.a.36242 · Cited by 13

Sorting nexin 1 loss results in increased oxidative stress and hypertension

Yang, J., Asico, L. D., Beitelshees, A. L., FERANIL, J. B., Wang, X., Jones, J. E., Armando, I., Cuevas, S., Schwartz, G. L., Gums, J. G., et al. (2020) · The FASEB Journal · doi:10.1096/fj.201902448r · Cited by 13

Rab2A-mediated Golgi-lipid droplet interactions support very-low-density lipoprotein secretion in hepatocytes

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Up-regulation of the active form of small GTPase Rab13 promotes macroautophagy in vascular endothelial cells

Zhang, L., Dai, F., Cui, L., Zhou, B., & Guo, Y. (2017) · Biochimica et Biophysica Acta (BBA) - Molecular Cell Research · doi:10.1016/j.bbamcr.2017.01.003 · Cited by 12

Sorting nexin 24 is required for α-granule biogenesis and cargo delivery in megakaryocytes

Lacey, J., Webster, S. J., Heath, P. R., Hill, C. J., Nicholson-Goult, L., Wagner, B. E., Khan, A. O., Morgan, N. V., Makris, M., & Daly, M. E. (2022) · Haematologica · doi:10.3324/haematol.2021.279636 · Cited by 12

Identification of novel transplantable GPCR recycling motif for drug discovery

Nooh, M. M., Mancarella, S., & Bahouth, S. W. (2016) · Biochemical Pharmacology · doi:10.1016/j.bcp.2016.09.011 · Cited by 11

Amino acid starvation‐induced LDLR trafficking accelerates lipoprotein endocytosis and LDL clearance

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Alteration in Rab11‐mediated endocytic trafficking of LDL receptor contributes to angiotensin II ‐induced cholesterol accumulation and injury in podocytes

Hu, J., Zhu, Z., Chen, Z., Yang, Q., Liang, W., & Ding, G. (2022) · Cell Proliferation · doi:10.1111/cpr.13229 · Cited by 11

RUNX1 isoforms regulate RUNX1 and target genes differentially in platelets-megakaryocytes: association with clinical cardiovascular events

Guan, L., Voora, D., Myers, R. A., Carpio‐Cano, F. D., & Rao, A. K. (2024) · Journal of Thrombosis and Haemostasis · doi:10.1016/j.jtha.2024.07.032 · Cited by 11

Rab18 maintains homeostasis of subcutaneous adipose tissue to prevent obesity-induced metabolic disorders

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Role of Rab5 in the formation of macrophage-derived foam cell

Chan, L., Hong, J., Pan, J., Li, J., Wen, Z., Shi, H., Ding, J., & Luo, X. (2017) · Lipids in Health and Disease · doi:10.1186/s12944-017-0559-6 · Cited by 9

Rab10-positive tubular structures represent a novel endocytic pathway that diverges from canonical macropinocytosis in RAW264 macrophages

Kawai, K., Nishigaki, A., Moriya, S., Egami, Y., & Araki, N. (2021) · Frontiers in Immunology · doi:10.3389/fimmu.2021.649600 · Cited by 9

Comparative proximity biotinylation implicates the small GTPase RAB18 in sterol mobilization and biosynthesis

Kiss, R. S., Chicoine, J., Khalil, Y., SLADEK, R. M., Chen, H., Pisaturo, A., Martin, C., Dale, J. D., Brudenell, T. A., Kamath, A., et al. (2023) · Journal of Biological Chemistry · doi:10.1016/j.jbc.2023.105295 · Cited by 9

Basement membrane diversification relies on two competitive secretory routes defined by Rab10 and Rab8 and modulated by dystrophin and the exocyst complex

Dennis, C., Pouchin, P., Richard, G., & Mirouse, V. (2024) · PLoS Genetics · doi:10.1371/journal.pgen.1011169 · Cited by 9

A Homozygous PPP1R21 Splice Variant Associated with Severe Developmental Delay, Absence of Speech, and Muscle Weakness Leads to Activated Proteasome Function

Hentschel, A., Meyer, N., Kohlschmidt, N., Groß, C., Sickmann, A., Schara, U., Förster, F., Töpf, A., Christiansen, J., Horváth, R., et al. (2023) · Molecular Neurobiology · doi:10.1007/s12035-023-03219-9 · Cited by 8

The combination of Ezetimibe and Statin: a new treatment for hypercholesterolemia

Nodari, S., Rocca, P., Saporetti, A., Bettari, L., Foresti, A. L., Tanghetti, E., Metra, M., & Cas, L. D. (2007) · Heart International · doi:10.4081/hi.2007.12 · Cited by 7

Rab11 is Required for Maintenance of Cell Shape Via βPS Integrin Mediated Cell Adhesion in Drosophila.

Bhuin, T., & Roy, J. K. (2012) · Europe PMC (PubMed Central) · Cited by 7

Vasa Vasorum Lumen Narrowing in Brain Vascular Hyalinosis in Systemic Hypertension Patients Who Died of Ischemic Stroke

Gychka, S. G., Shults, N. V., Nikolaienko, S. I., Marcocci, L., Sariipek, N. E., Rybka, V., Malysheva, T. A., Dibrova, V. A., Suzuki, Y., & Gavrish, A. S. (2020) · International Journal of Molecular Sciences · doi:10.3390/ijms21249611 · Cited by 7

Adverse Reactions to Evolocumab: Analysis of Real-World Data from EudraVigilance

Calapai, F., Mannucci, C., Currò, M., Cardia, L., Esposito, E., Calapai, G., & Ammendolia, I. (2024) · Pharmaceuticals · doi:10.3390/ph17030364 · Cited by 7

Regulation of the Trafficking and Function of G Protein‐Coupled Receptors by Rab1 GTPase in Cardiomyocytes

Wu, G. (2008) · Methods in enzymology on CD-ROM/Methods in enzymology · doi:10.1016/s0076-6879(07)38016-6 · Cited by 6

Data mining for traffic information

Clague, M. J., & Urbé, S. (2020) · Traffic · doi:10.1111/tra.12702 · Cited by 6

CD137-CD137L Aggravates Calcification of Vascular Smooth Muscle Cell and Vasculature of ApoE−/− Mice Via Rab7-Mediated Autophagy

Yang, P., Zang, G., Yang, Y., Zhong, W. H., Li, B., Xu, Y., Shao, C., Wang, Z., Pu, J., & Yuan, W. (2022) · Journal of Cardiovascular Translational Research · doi:10.1007/s12265-022-10272-7 · Cited by 6

SNX3 Promotes Doxorubicin-Induced Cardiomyopathy by Regulating GPX4-Mediated Ferroptosis

Huang, S., Zou, F., Zhou, H., & He, J. (2024) · International Journal of Medical Sciences · doi:10.7150/ijms.95466 · Cited by 5

PI3KC2β depletion rescues endosomal trafficking defects in Mtm1 knockout skeletal muscle cells

Mansat, M., Kpotor, A. O., Mazars, A., Chicanne, G., Payrastre, B., & Viaud, J. (2025) · Journal of Lipid Research · doi:10.1016/j.jlr.2025.100756 · Cited by 5

Pooled RCTs: Lowering LDL-C levels using statins reduces major vascular events in all age groups

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SNX5-Rab11a protects against cardiac hypertrophy through regulating LRP6 membrane translocation

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