The DOI matches its Crossref record; 170 of the 170 references it cites were found in a registry or an index.
Cell-cycle control and cortical development
Abstract
The spatio-temporal timing of the last round of mitosis, followed by the migration of neuroblasts to the cortical plate leads to the formation of the six-layered cortex that is subdivided into functionally defined cortical areas. Whereas many of the cellular and molecular mechanisms have been established in rodents, there are a number of unique features that require further elucidation in primates. Recent findings both in rodents and in primates indicate that regulation of the cell cycle, specifically of the G1 phase has a crucial role in controlling area-specific rates of neuron production and the generation of cytoarchitectonic maps.
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“oRGs are present in large numbers in gyrencephalic primates22,23,40–44 and are considered pivotal to the evolutionary increase in human cortex size and complexity45,46.”
From The use of brain organoids to investigate neural development and disease (2017) · cites this paper as [43]
In the citing paper
“Interestingly, G1/S transition rates might be associated with these cell decisions as symmetric divisions can have shorter G1/S transition times than asymmetric divisions [93, 101].”
From The ASD Living Biology: from cell proliferation to clinical phenotype (2019) · cites this paper as [93]
Citations
Cites
Inhibitors of mammalian G1 cyclin-dependent kinases.Preprint
Sherr, C. J., & Roberts, J. M. (1995) · Genes & Development · doi:10.1101/gad.9.10.1149 · Cited by 3,242
Specification of Cerebral Cortical Areas
Rakic, P. (1988) · Science · doi:10.1126/science.3291116 · Cited by 3,127 · cited 1×
“Because these distinct proliferative programmes generate areal differences prior to the arrival of thalamic fibres, they imply the presence of an intrinsic, defined developmental programme and are compatible with the concept of the protomap theor”
ResultKing, M.-C., & Wilson, A. C. (1975) · Science · doi:10.1126/science.1090005 · Cited by 2,815
Noctor, S. C., Martínez-Cerdeño, V., Ivic, L., & Kriegstein, A. R. (2004) · Nature Neuroscience · doi:10.1038/nn1172 · Cited by 2,229
The cell biology of neurogenesis
Götz, M., & Huttner, W. B. (2005) · Nature Reviews Molecular Cell Biology · doi:10.1038/nrm1739 · Cited by 2,130
Neurons derived from radial glial cells establish radial units in neocortex
Noctor, S. C., Flint, A. C., Weissman, T. A., Dammerman, R. S., & Kriegstein, A. R. (2001) · Nature · doi:10.1038/35055553 · Cited by 2,016
Nakayama, K., Ishida, N., Shirane, M., Inomata, A., Inoue, T., SHISHIDO, N., Horii, I., Loh, D. Y., & Nakayama, K. (1996) · Cell · doi:10.1016/s0092-8674(00)81237-4 · Cited by 1,548
Autoradiographic Study of Cell Migration during Histogenesis of Cerebral Cortex in the Mouse
ANGEVINE, J. B., & SIDMAN, R. L. (1961) · Nature · doi:10.1038/192766b0 · Cited by 1,530
Regulation of Cerebral Cortical Size by Control of Cell Cycle Exit in Neural Precursors
Chenn, A., & Walsh, C. A. (2002) · Science · doi:10.1126/science.1074192 · Cited by 1,431
Rakic, P. (1974) · Science · doi:10.1126/science.183.4123.425 · Cited by 1,161
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Research works printed but not linked: 2
- Polleux, F., Dehay, C. & Kennedy, H. Gradients and timing of the arrival of thalamic axons in the mouse neocortex. Soc. Neurosci. Abstr. 22, 1012 (1996).
- Kennedy, H., Douglas, R. J., Knoblauch, K. & Dehay, C. Self-organization and pattern formation in cortical networks in the primate. Novartis Found. Symp. in the press.
Cited by
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Items 401–500 of 654
A simple method for multiday imaging of slice cultures
Seidl, A. H., & Rubel, E. W. (2009) · Microscopy Research and Technique · doi:10.1002/jemt.20750 · Cited by 14
Transcriptional Regulation and Alternative Splicing Make for Better Brains
Dehay, C., & Kennedy, H. (2009) · Neuron · doi:10.1016/j.neuron.2009.05.006 · Cited by 14
“However, alongside a number of core mechanisms that are conserved between rodents and primates, there are major differences in the nature and timing of ontogenetic processes characterizing primate corticogenesis (Dehay and Kennedy, 2007).”
BackgroundSelf-citationPrenatal Development of the Human Fetal Telencephalon
Judáš, M. (2010) · Medical radiology · doi:10.1007/174_2010_119 · Cited by 14
Dee, A. R., Li, K., Heng, X., Guo, Q., & Li, J. Y. H. (2016) · Development · doi:10.1242/dev.138537 · Cited by 14
“It is well-known that self-renewal of neural stem/progenitor cells (NSPCs) is inversely correlated with cell cycle length, especially G1 duration (Dehay and Kennedy, 2007; Salomoni and Calegari, 2010).”
BackgroundRegulation of cytokinesis during corticogenesis: focus on the midbody
Johnson, C. A., Wright, C. E., & Ghashghaei, H. T. (2017) · FEBS Letters · doi:10.1002/1873-3468.12676 · Cited by 14
Stability of Control Networks in Autonomous Homeostatic Regulation of Stem Cell Lineages
Komarova, N. L., & den Driessche, P. V. (2017) · Bulletin of Mathematical Biology · doi:10.1007/s11538-017-0283-4 · Cited by 15
Kimura, E., Kubo, K.-I., Endo, T., Ling, W.-T., Nakajima, K., Kakeyama, M., & Tohyama, C. (2017) · PLoS ONE · doi:10.1371/journal.pone.0183497 · Cited by 16
Mi, D., Manuel, M. N., Huang, Y.-T., Mason, J. O., & Price, D. J. (2018) · Frontiers in Cellular Neuroscience · doi:10.3389/fncel.2018.00419 · Cited by 13
“G1 length is increased in neurogenic progenitors compared with proliferative progenitors (Caviness et al., 2003; Lukaszewicz et al., 2005; Dehay and Kennedy, 2007; Salomoni and Calegari, 2010).”
BackgroundDifferent neural crest populations exhibit diverse proliferative behaviors
Gonsalvez, D. G., Li‐Yuen‐Fong, M., Cane, K. N., Stamp, L. A., Young, H. M., & Anderson, C. R. (2014) · Developmental Neurobiology · doi:10.1002/dneu.22229 · Cited by 13
“In many populations of dividing cells, the length of G1 is thought to be a crucial factor in regulating the choice between differentiation and continued division (Dehay and Kennedy, 2007; Salomoni and Calegari, 2010).”
BackgroundReal Time Imaging of Human Progenitor Neurogenesis
Keenan, T. M., Nelson, A. D., Grinager, J. R., Thelen, J. C., & Svendsen, C. N. (2010) · PLoS ONE · doi:10.1371/journal.pone.0013187 · Cited by 13
“As neurogenesis proceeds other types of progenitors provide secondary sources of neurons (reviewed in [12,13,14,15]).”
BackgroundInfluentialZhou, L., & Luo, H. (2013) · Journal of Neuroscience · doi:10.1523/jneurosci.3357-12.2013 · Cited by 13
“Cell cycle regulation may be an important mechanism underlying the transition from proliferative to differentiative divisions of NE cells (Dehay and Kennedy, 2007).”
BackgroundO’Driscoll, M. (2016) · The Journal of Pathology · doi:10.1002/path.4828 · Cited by 12
D’Aniello, B., Cosmo, A. D., Scandurra, A., & Pinelli, C. (2019) · Frontiers in Neuroanatomy · doi:10.3389/fnana.2019.00086 · Cited by 13
“, 2011) and mammals (Dehay and Kennedy, 2007) drawn the same conclusion.”
BackgroundSpecification of Cortical Projection Neurons
MacDonald, J. L., Fame, R. M., Azim, E., Shnider, S. J., Molyneaux, B. J., Arlotta, P., & Macklis, J. D. (2013) · Elsevier eBooks · doi:10.1016/b978-0-12-397265-1.00098-8 · Cited by 14
Neuronal networks and controlled symmetries, a generic frameworkPreprint
Gérard, L., & Slotine, J.-J. E. (2006) · arXiv (Cornell University) · doi:10.48550/arxiv.q-bio/0612049 · Cited by 13
“o 1 arXiv:q-bio/0612049v3 [q-bio.NC] 31 Dec 2007 input cortical layers [12]. Recent research suggests that this \paucity of input" between dierent regions of the brain is actually quite general [13]. Inspired by this, we will try in the second section of the paper to draw a generic framework allowing to observe n…”
BackgroundRoussat, M., Jungas, T., Audouard, C., Omerani, S., Médevielle, F., Agius, E., Davy, A., Pituello, F., & Bel-Vialar, S. (2023) · Journal of Neuroscience · doi:10.1523/jneurosci.0825-22.2022 · Cited by 12
Zhang, X.-P., Wang, X., Wang, S.-N., & Miao, C. (2023) · Neural Regeneration Research · doi:10.4103/1673-5374.369100 · Cited by 13
“The in vivo generation of diverse cell types follows a temporal sequence, and newborn excitatory glutamatergic neurons can migrate radially to their destined positions in an “inside-out” pattern (Dehay and Kennedy, 2007; Silbereis et al., 2016).”
BackgroundButler, K., Martinez, L. A., & Tejada-Simon, M. V. (2012) · Genes Brain & Behavior · doi:10.1111/gbb.12014 · Cited by 12
“…of progenitor cells as well as in postmitotic neurons have been associated with tumourigenesis (Weiss 2000), inadequate brain development (Guillemot 2005; Dehay & Kennedy 2007), and learning and memory problems (Saxe et al. 2006; Dupret et al. 2008; Jessberger et al. 2009; Deng et al. 2010).”
Cell cycle activity of neural precursors in the diseased mammalian brain
Alonso, S. B., Schulze-Steikow, M., & Calegari, F. (2014) · Frontiers in Neuroscience · doi:10.3389/fnins.2014.00039 · Cited by 11
“, Yang, J. J., and Chopp, M. (2006). Reduction of the cell cycle length by decreasing G1 phase and cell cycle reentry expand neuronal progenitor cells in the subventricular zone of adult rat after stroke.”
InfluentialDetection of Apoptosis in the Central Nervous System
Lee, Y., & McKinnon, P. J. (2009) · Methods in molecular biology · doi:10.1007/978-1-60327-017-5_19 · Cited by 12
España‐Serrano, L., Martín-Palanco, N. G., Montero‐Pedrazuela, A., Pérez‐Santamarina, E., Vidal, R., García‐Consuegra, I., Valdizán, E. M., Pazos, Á., Palomo, T., Jiménez‐Arriero, M. Á., et al. (2016) · Cerebral Cortex · doi:10.1093/cercor/bhw129 · Cited by 12
Kang, B., Yang, Y., Hu, K., Ruan, X., Liu, Y.-L., Lee, P., Lee, J., Wang, J., & Zhang, X. (2023) · Genome Research · doi:10.1101/gr.277864.123 · Cited by 11
“The dorsal excitatory and ventral inhibitory neuronal lineages display divergent neurogenesis, migration, and differentiation features (Dehay and Kennedy 2007) but showed 3 ′ -UTR lengthening and overlapping PA changes in both neurogenesis lineages based on the original cell-type annotations and…”
BackgroundHarb, K., Richter, M., Neelagandan, N., Magrinelli, E., Harfoush, H., Kuechler, K., Henis, M., Hermanns-Borgmeyer, I., de Anda, F. C., & Duncan, K. E. (2022) · eLife · doi:10.7554/elife.55199 · Cited by 11
Trp53 ablation fails to prevent microcephaly in mouse pallium with impaired minor intron splicing
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Yang, J., Sun, Z., & Komarova, N. L. (2015) · Mathematical Biosciences · doi:10.1016/j.mbs.2015.06.001 · Cited by 11
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MethodHinaut, X., & Dominey, P. F. (2011) · Journal of Physiology-Paris · doi:10.1016/j.jphysparis.2011.07.010 · Cited by 11
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Borello, U., Kennedy, H., & Dehay, C. (2017) · Seminars in Cell and Developmental Biology · doi:10.1016/j.semcdb.2017.08.047 · Cited by 11
Self-citationDnmt1-dependent Chk1 pathway suppression is protective against neuron division
Oshikawa, M., Okada, K., Tabata, H., Nagata, K., & Ajioka, I. (2017) · Development · doi:10.1242/dev.154013 · Cited by 11
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“75-78 In addition, we investigated the differential gene expression profiles in the SVZ by spatial transcriptomics using Patient 1 and Control cerebral organoids (Supplementary Fig.”
BackgroundZhang, J., Che, P., Yang, Z., Zhang, P., Shui, Y., Lu, X., Xu, J., She, Y., Zhang, Y., Yu, J. Q., et al. (2025) · PLoS Biology · doi:10.1371/journal.pbio.3003175 · Cited by 10
Jiang, L., Genon, S., Ye, J., Zhu, Y., Wang, G., He, R., Valdes-Sosa, P. A., Wan, F., Yao, D., Eickhoff, S. B., et al. (2025) · Nature Communications · doi:10.1038/s41467-025-63000-5 · Cited by 11
“The regulation of the cell cycle exerts critical control over region-speci fi c rates of neuronal generation and the formation of cytoarchitectonic maps 43 .”
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Kim, W.-Y. (2015) · Communicative & Integrative Biology · doi:10.4161/19420889.2014.994377 · Cited by 10
“Cell cycle regulation plays an important role in the number of neurons produced in the developing brain.(1) Changes in cell cycle progression such as cell cycle length and re-entry/exit alter brain size.”
BackgroundYang, D., Wu, X., Zhou, Y., Wang, W., & Wang, Z. (2020) · EMBO Reports · doi:10.15252/embr.201949431 · Cited by 11
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Song, B., Zhang, Y., Xiong, G., Luo, H., Zhang, B., Li, Y., Wang, Z., Zhou, Z., & Chang, X. (2022) · Cell Biology and Toxicology · doi:10.1007/s10565-022-09775-5 · Cited by 11
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BackgroundChao, M., Kuo, H.-C., Tong, S.-Y., Yang, Y.-S., Chuang, Y.-C., & Tseng, C. (2018) · Toxicological Sciences · doi:10.1093/toxsci/kfy306 · Cited by 10
Prenatal Exposure to Gossypol Impairs Corticogenesis of Mouse
Zhu, X., Wu, Y., Li, C., Yan, W., Pan, J., Wang, S., & Zhao, S. (2020) · Frontiers in Neuroscience · doi:10.3389/fnins.2020.00318 · Cited by 10
“In neural cells, proliferation and growth arrest are regulated by a balance of intrinsic and extrinsic factors that direct entry and exit from the cell cycle (Cunningham and Roussel, 2001; Dehay and Kennedy, 2007).”
BackgroundXu, J., Zhao, R., Yan, M., Zhou, M. R., Liu, H., Wang, X., Lu, C. F., Li, Q., Mo, Y., Zhang, P., et al. (2024) · International Journal of Molecular Sciences · doi:10.3390/ijms25189885 · Cited by 9
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BackgroundLee, J. Y. (2019) · Journal of Korean Neurosurgical Society · doi:10.3340/jkns.2019.0098 · Cited by 9
Kennedy, H., Wianny, F., & Dehay, C. (2020) · Current Opinion in Neurobiology · doi:10.1016/j.conb.2020.09.012 · Cited by 11
“This made it possible to examine the spatio-temporal dynamics of cortical layer and area formation [4].”
BackgroundMethodSelf-citationModeling spatial population dynamics of stem cell lineage in tissue growth
Cao, Y., Liang, C., Naveed, H., Li, Y., Chen, M., & Nie, Q. H. (2012) · Annual International Conference of the IEEE Engineering in Medicine and Biology Society (EMBC) · doi:10.1109/embc.2012.6347240 · Cited by 9
“of rodent and primate embryonic cortex [11].”
Tran, D. N., Park, S.-M., Jung, E., & Jeung, E. (2021) · International Journal of Molecular Sciences · doi:10.3390/ijms222312949 · Cited by 10
“In the cerebral cortex, neurons were generated in the cortical ventricular zone (VZ) and subventricular zone (SVZ), which migrate radially to their appropriate position, resulting in the formation of cortical layers in an inside-out manner [20].”
BackgroundCingulate sulcus morphology and paracingulate sulcus variations: Anatomical and radiological studies
Selahi, Ö., Bektaşoğlu, P. K., Hakan, T., Fırat, Z., Güngör, A., & Çelikoğlu, E. (2022) · Clinical Anatomy · doi:10.1002/ca.23981 · Cited by 9
“…sulcus, (A) Anterior the genu, (B) Posterior to genu, (C) From anterior commissure level key factors, like differential expressions of transcription factors and variance in cell proliferation during brain development, might contribute to variance in cortical morphology (Dehay & Kennedy, 2007).”
BackgroundUbiquitous lognormal distribution of neuron densities in mammalian cerebral cortex
Morales-Gregorio, A., van Meegen, A., & van Albada, S. J. (2023) · Cerebral Cortex · doi:10.1093/cercor/bhad160 · Cited by 9
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BackgroundInfluentialRNA helicase Mov10 is essential for gastrulation and central nervous system development
Skariah, G., Perry, K. J., Drnevich, J. M., Henry, J. J., & Ceman, S. (2017) · Developmental Dynamics · doi:10.1002/dvdy.24615 · Cited by 9
“As the neural stem cells become depleted through their differentiation into neurons, the ventricular zone becomes diminished (Dehay and Kennedy, 2007).”
BackgroundWang, Q., Yang, L., Alexander, C. M., & Temple, S. (2012) · PLoS ONE · doi:10.1371/annotation/76cf3bd3-f842-489f-8ad2-4c016447b84c · Cited by 9
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Yang, X., Zhang, C., Guo, T.-Z., Feng, Y., LIU, Q., Chen, Y., & Zhang, Q. (2015) · Molecular Medicine Reports · doi:10.3892/mmr.2015.3171 · Cited by 8
“CyclinD2 is a member of D-type cyclins and is crucial in the progression of the cell cycle (19).”
Li, X., Yan, M., Guo, Z., Li, Y., Feng, R., Zhu, H., Tu, X., Yu, S. S. B., & Chen, J.-G. (2020) · Neuroscience · doi:10.1016/j.neuroscience.2020.09.044 · Cited by 9
Ishihara, K. (2021) · Genes · doi:10.3390/genes12101598 · Cited by 8
“In embryonic cortical neurogenesis, the importance of cell cycle regulation has been suggested [35,36].”
BackgroundProdromidou, K., & Matsas, R. (2021) · Cellular and Molecular Life Sciences · doi:10.1007/s00018-021-04063-7 · Cited by 11
Specification of cortical projection neurons
Özkan, A., MacDonald, J. L., Fame, R. M., Itoh, Y., Peter, M., Durak, O., & Macklis, J. D. (2020) · Elsevier eBooks · doi:10.1016/b978-0-12-814405-3.00019-9 · Cited by 9
Expression of cyclin E in postmitotic neurons during development and in the adult mouse brain
Ikeda, Y., Matsunaga, Y., Takiguchi, M., & Ikeda, M. (2010) · Gene Expression Patterns · doi:10.1016/j.gep.2010.09.004 · Cited by 8
Ferguson, R., Serafeimidou‐Pouliou, E., & Subramanian, V. (2016) · Journal of Anatomy · doi:10.1111/joa.12526 · Cited by 9
“5 (Dehay & Kennedy, 2007).”
Çağlayan, E. (2016) · Cell Biology International · doi:10.1002/cbin.10694 · Cited by 10
“Regulation of the cell cycle is critical and particularly G1 phase in the cell cycle is important for the normal expansion of the mammalian neocortex (Dehay and Kennedy, 2007).”
BackgroundHoffmann, N., Weise, S. C., Marinaro, F., Vogel, T., & Tonelli, D. D. P. (2018) · Frontiers in Neuroscience · doi:10.3389/fnins.2018.00281 · Cited by 7
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BackgroundA triphenylethylene nonsteroidal SERM attenuates cervical cancer growth
Chauhan, N., Maher, D. M., Yallapu, M. M., Hafeez, B. B., Singh, M. M., Chauhan, S. C., & Jaggi, M. (2019) · Scientific Reports · doi:10.1038/s41598-019-46680-0 · Cited by 8
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Sobue, K., & Fukumoto, K. (2010) · Cell Adhesion & Migration · doi:10.4161/cam.4.2.10886 · Cited by 8
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BackgroundSeeking clues in brain development to explain the extraordinary evolution of language in humans
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“From a developmental perspective, Dehay and Kennedy (2007) have argued that layers 2 and 3 in primates are different from layers 2 and 3 in mice, which lack the computational components of primate cortex.”
BackgroundInterareal Connections of the Macaque Cortex
Anderson, J. C., & Martin, K. A. C. (2016) · Elsevier eBooks · doi:10.1016/b978-0-12-801393-9.00006-2 · Cited by 7
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Ambrozkiewicz, M. C., Bessa, P., Salazar-Lázaro, A., Salina, V., & Tarabykin, V. S. (2017) · Journal of Neuroscience Methods · doi:10.1016/j.jneumeth.2017.07.023 · Cited by 9
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Massimo, M., & Long, K. R. (2021) · Seminars in Cell and Developmental Biology · doi:10.1016/j.semcdb.2021.09.007 · Cited by 6
Barks, S. K., Bauernfeind, A., Bonar, C., Cranfield, M., de Sousa, A. D., Erwin, J., Hopkins, W. D., Lewandowski, A., Mudakikwa, A. B., Phillips, K. A., et al. (2014) · The Journal of comparative neurology · doi:10.1002/cne.23448 · Cited by 6
“The tension-based theory of morphological development proposes that gyrification of the neocortex occurs because of tension in white matter tracts that draws interconnected regions of cortex closer (Dehay et al., 1996; Van Essen, 1997; Dehay and Kennedy, 2007; Zilles et al., 2013).”
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“…progenitor that is found at much higher frequency in humans than in mice, and it has been hypothesized to be crucial for the morphogenesis of the characteristic convolutions (gyri and sulci) of the primate cortex (Dehay & Kennedy, 2007; Lui, Hansen, & Kriegstein, 2011; Molnar et al., 2006).”
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“whereas the former play an inhibitory role [11, 39, 40].”
BackgroundSubtype Specification of Cerebral Cortical Neurons in Their Immature Stages
Oishi, K., & Nakajima, K. (2017) · Neurochemical Research · doi:10.1007/s11064-017-2441-3 · Cited by 8
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Borello, U., Berarducci, B., Delahaye, E., Price, D. J., & Dehay, C. (2018) · Frontiers in Neuroscience · doi:10.3389/fnins.2018.00119 · Cited by 6
“During corticogenesis, proliferative and differentiative divisions are characterized by short and long G1 phases respectively (Dehay et al., 2001; Lukaszewicz et al., 2002, 2005; Calegari and Huttner, 2003; Dehay and Kennedy, 2007; Pilaz et al., 2009).”
BackgroundSelf-citationCheng, X.-R., Li, K., Liu, M., Xu, M.-R., Hu, X., Yan, R.-C., Förster, E., & Zhao, S.-T. (2018) · Developmental Biology · doi:10.1016/j.ydbio.2018.06.016 · Cited by 6
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Magrou, L., Barone, P., Markov, N. T., Scheeren, G., Killackey, H. P., Giroud, P., Berland, M., Knoblauch, K., Dehay, C., & Kennedy, H. (2019) · Cerebral Cortex · doi:10.1093/cercor/bhz175 · Cited by 8
Self-citationBail, R. L., Bonafina, A., Espuny-Camacho, I., & Nguyen, L. (2020) · Current Opinion in Neurobiology · doi:10.1016/j.conb.2020.10.018 · Cited by 6
“Intrinsic factors regulating the cell cycle also control the choice of proliferative versus neurogenic progenitor divisions [35,36].”
BackgroundKa, M., Moffat, J. J., & Kim, W.-Y. (2021) · Cellular and Molecular Neurobiology · doi:10.1007/s10571-021-01088-1 · Cited by 6
Temporal changes in the brain lipidome during neurodevelopment of Smith–Lemli–Opitz syndrome mice
Li, A., Hines, K. M., Ross, D. H., MacDonald, J. W., & Xu, L. (2022) · The Analyst · doi:10.1039/d2an00137c · Cited by 6
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Mann, B., Crawford, J. C., Reddy, K., Lott, J., Youn, Y. H., Gao, G., Guy, C. S., Chou, C., Darnell, D., Trivedi, S., et al. (2023) · mBio · doi:10.1128/mbio.00510-23 · Cited by 6
“The division mode of NPCs is closely associated with cell cycle kinetics (34).”
BackgroundThe transcription factor NF-YA is crucial for neural progenitor maintenance during brain development
Yamanaka, T., Kurosawa, M., Yoshida, A., Shimogori, T., Hiyama, A., Maity, S. N., Hattori, N., Matsui, H., & Nukina, N. (2024) · Journal of Biological Chemistry · doi:10.1016/j.jbc.2024.105629 · Cited by 6
PML: a tumor suppressor essential for neocortical development
Schreck, K. C., & Gaiano, N. (2009) · Nature Neuroscience · doi:10.1038/nn0209-108 · Cited by 6
Kalebic, N., Long, K. R., & Huttner, W. Β. (2016) · Elsevier eBooks · doi:10.1016/b978-0-12-804042-3.00136-6 · Cited by 6
Molnár, Z., & Price, D. J. (2015) · Elsevier eBooks · doi:10.1016/b978-0-12-800043-4.00019-1 · Cited by 6
Ledesma-Terrón, M., Peralta-Cañadas, N., & Míguez, D. G. (2020) · Development · doi:10.1242/dev.189712 · Cited by 6
“Variable cell cycle dynamics have been reported in many developmental systems (Míguez, 2015; Saade et al., 2013; Le Dréau et al., 2014; Takahashi et al., 1995; Calegari and Huttner, 2003; Calegari et al., 2005; Dehay and Kennedy, 2007; Mairet-Coello et al., 2012; Roccio et al., 2013; Arai et al., 2011; Iulianella et a…”
BackgroundEarly Purkinje Cell Development and the Origins of Cerebellar Patterning
Casoni, F., Croci, L., Cremona, O., Hawkes, R. B., & Consalez, G. G. (2017) · Contemporary clinical neuroscience · doi:10.1007/978-3-319-59749-2_4 · Cited by 6
Erratum: Cell-cycle control and cortical development
Dehay, C., & Kennedy, H. (2007) · Nature reviews. Neuroscience · doi:10.1038/nrn2176 · Cited by 6
Self-citationStem cells: slow and steady wins the race
Huttner, W. Β. (2015) · Nature Neuroscience · doi:10.1038/nn.4009 · Cited by 5
Responses to predation pressure involve similar sets of genes in two divergent species of Daphnia
Zhang, X., Wolinska, J., Blair, D., Hu, W., & Yin, M. (2023) · Journal of Animal Ecology · doi:10.1111/1365-2656.13969 · Cited by 5
Modulation of the Generation of Dopaminergic Neurons from Human Neural Stem Cells by Bcl-XL
Martı́nez-Serrano, A., Castillo, C. G., Courtois, E. T., García-García, E., & Liste, I. (2011) · Vitamins and hormones · doi:10.1016/b978-0-12-386015-6.00029-9 · Cited by 5
“Cell cycle and cell fate choice have been linked in many situations, for example, the forced exit of cell cycle induced by cdk inhibitors has the consequence of altering cell fate (Dehay and Kennedy, 2007; Doe, 2008).”
BackgroundGulden, F. O., & Šestan, N. (2014) · Nature · doi:10.1038/515206a · Cited by 5
Oishi, K., Nakajima, K., & Motoyama, J. (2022) · Journal of Developmental Biology · doi:10.3390/jdb10040050 · Cited by 5
“subtype determinants, which actually occur in Drosophila NPCs [20], have been postulated [21].”
BackgroundStem Cells: Neural Stem Cells in Cerebral Cortex Development
Mora‐Bermúdez, F., Garcίa, M. T., & Huttner, W. Β. (2012) · Springer eBooks · doi:10.1007/978-1-4614-1997-6_7 · Cited by 5
Radiation Induced DNA Damage, Repair and Therapeutics
Harrison, L. (2013) · CRC Press eBooks · doi:10.1201/b14587-14 · Cited by 5
A balancing Akt: How to fine-tune neuronal migration speed
Itoh, Y. (2016) · Neurogenesis · doi:10.1080/23262133.2016.1256854 · Cited by 5
Lee, W., Kang, B., Kim, H., Ishida, T., Shin, M., Iwashita, M., Nitta, M., Shiraishi, A., Kiyonari, H., Shimoya, K., et al. (2024) · The EMBO Journal · doi:10.1038/s44318-024-00325-9 · Cited by 4
“Another possible prominent factor in deciding the cell fate of NSCs is the length of the cell cycle (Dalton, 2015; Dehay and Kennedy, 2007; Salomoni and Calegari, 2010).”
Ohtsuka, M., Soumiya, H., Hanai, M., Furukawa, S., & Fukumitsu, H. (2013) · Biomedical Research · doi:10.2220/biomedres.34.231 · Cited by 4
“Several studies have revealed the involvement of intrinsic factors, such as transcription factors, and cell cycle regulators in this process (4, 5).”
BackgroundVincenti, A. P. D., Bonafina, A., Ledda, F., & Paratcha, G. (2024) · Development · doi:10.1242/dev.202879 · Cited by 5
Regional control of cortical lamination
Waclaw, R. R., & Campbell, K. (2009) · Nature Neuroscience · doi:10.1038/nn1009-1211 · Cited by 4
Huang, Y., Song, H., Tao, Y., Shao, X., Zeng, X., Xu, X., Qi, J., & Sun, J.-F. (2018) · PLoS ONE · doi:10.1371/journal.pone.0195610 · Cited by 4
Area patterning of the mammalian neocortex
Grove, E. A. (2020) · Elsevier eBooks · doi:10.1016/b978-0-12-814405-3.00003-5 · Cited by 4
Srakočić, S., Gorup, D., Kutlić, D., Petrović, A., Tarabykin, V. S., & Gajović, S. (2023) · Scientific Reports · doi:10.1038/s41598-023-35515-8 · Cited by 4
Ernsberger, U. (2014) · Cell and Tissue Research · doi:10.1007/s00441-014-2049-8 · Cited by 5
Charvet, C. J. (2014) · Frontiers in Human Neuroscience · doi:10.3389/fnhum.2014.00190 · Cited by 4
“At some point, many of the cells switch from undergoing symmetrical proliferative to asymmetrical cell divisions, where one daughter cell is non-proliferative and the other cell is proliferative (Dehay and Kennedy, 2007).”
BackgroundDiversity and Evolution of Human Cortical Progenitor Cell Types
Pollen, A. A., & Kriegstein, A. R. (2023) · Wiley eBooks · doi:10.1002/9781119860914.ch2 · Cited by 5
Vancamp, P., Frapin, M., Parnet, P., & Amarger, V. (2024) · Biological Psychiatry Global Open Science · doi:10.1016/j.bpsgos.2024.100339 · Cited by 5
“Consequently, premature cell cycle exit can result in cellular hypoplasia and precocious neurogenesis (66).”
Background
Metadata
- Authors
- Dehay, C., & Kennedy, H.
- Affiliations
- Lyon 1 Université (FR)
- Corresponding author
- Dehay, Colette
- Venue
- Nature Reviews Neuroscience
- Published
- 2007-06
- Volume
- 8
- Issue
- 6
- Pages
- 438-450
- ISSN
- 1471-003X (ISSN-L)
- 1471-0048
- OpenAlex
- W2010852678
- Cited by
- 655
- References
- 170
- Citations by year
- 2026: 9 · 2025: 15 · 2024: 17 · 2023: 28 · 2022: 18 · 2021: 30 · 2020: 39 · 2019: 30 · 2018: 47 · 2017: 36 · 2016: 39 · 2015: 34 · 2014: 61 · 2013: 52 · 2012: 47
- FWCI
- 3.18
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- Nature reviews. Neuroscience (publishedVersion)
- PubMed (publishedVersion)
- Topics
- Life Sciences › Neuroscience › Developmental Neuroscience › Neurogenesis and neuroplasticity mechanisms
- Life Sciences › Biochemistry, Genetics and Molecular Biology › Molecular Biology › Developmental Biology and Gene Regulation
- Life Sciences › Biochemistry, Genetics and Molecular Biology › Molecular Biology › Congenital heart defects research
- Keywords
- cortical development, cell cycle regulation, G1 phase, neuronal proliferation, neuronal differentiation, neuroblast migration, cortical plate, cortical lamination, cortical regions, cytoarchitecture, primate cortex, rodent cortex
- MeSH terms
- Animals, Cell Communication, Cell Cycle, Cell Differentiation, Cerebral Cortex, Humans, Neurons, Stem Cells, Signal Transduction, G1 Phase, Cell Cycle Proteins, Cell Proliferation
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