Tau-mediated neurodegeneration in Alzheimer’s disease and related disorders

Triple-Transgenic Model of Alzheimer’s Disease with Plaques and Tangles

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Protein aggregation and neurodegenerative disease

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The blood-brain barrier: Bottleneck in brain drug development

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Neurofibrillary tangles but not senile plaques parallel duration and severity of Alzheimer's disease

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Synapse Loss and Microglial Activation Precede Tangles in a P301S Tauopathy Mouse Model

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Tau protein isoforms, phosphorylation and role in neurodegenerative disorders11These authors contributed equally to this work.

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Tau Suppression in a Neurodegenerative Mouse Model Improves Memory Function

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Reducing Endogenous Tau Ameliorates Amyloid ß-Induced Deficits in an Alzheimer's Disease Mouse Model

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Oxidative stress in neurodegeneration: Cause or consequence?

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The distribution of tau in the mammalian central nervous system.

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Transplantation of Human Menstrual Blood-Derived Mesenchymal Stem Cells Alleviates Alzheimer’s Disease-Like Pathology in APP/PS1 Transgenic Mice

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Ozone atmospheric pollution and Alzheimer's disease: from epidemiological facts to molecular mechanisms

Croze, M. L., & Zimmer, L. (2018) · Journal of Alzheimer s Disease · doi:10.3233/jad-170857 · Cited by 78

Loss of Hsp110 Leads to Age-Dependent Tau Hyperphosphorylation and Early Accumulation of Insoluble Amyloid β

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Postmortem Brain, Cerebrospinal Fluid, and Blood Neurotrophic Factor Levels in Alzheimer’s Disease: A Systematic Review and Meta-Analysis

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Antibody-mediated clearance of tau in primary mouse microglial cultures requires Fcγ-receptor binding and functional lysosomes

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Tau, Glial Fibrillary Acidic Protein, and Neurofilament Light Chain as Brain Protein Biomarkers in Cerebrospinal Fluid and Blood for Diagnosis of Neurobiological Diseases

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HDAC6 inhibition results in tau acetylation and modulates tau phosphorylation and degradation in oligodendrocytes

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The molecular basis of frontotemporal dementia

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NMDA receptor dysfunction contributes to impaired brain‐derived neurotrophic factor‐induced facilitation of hippocampal synaptic transmission in a T au transgenic model

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Precision Modulation of Neurodegenerative Disease-Related Gene Expression in Human iPSC-Derived Neurons

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BDNF Val66Met moderates memory impairment, hippocampal function and tau in preclinical autosomal dominant Alzheimer’s disease

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Review: Disruption of the Postsynaptic Density in Alzheimer’s Disease and Other Neurodegenerative Dementias

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Towards a Unified Vision of Copper Involvement in Alzheimer's Disease: A Review Connecting Basic, Experimental, and Clinical Research

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Voxel-based analysis of Alzheimer's disease PET imaging using a triplet of radiotracers: PIB, FDDNP, and FDG

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Lowering Synaptogyrin-3 expression rescues Tau-induced memory defects and synaptic loss in the presence of microglial activation

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Microtubule associated proteins as targets for anticancer drug development

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The formation of tau pore-like structures is prevalent and cell specific: possible implications for the disease phenotypes

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Fluorescence Self-Quenching from Reporter Dyes Informs on the Structural Properties of Amyloid Clusters Formed in Vitro and in Cells

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Endoplasmic reticulum stress responses in mouse models of Alzheimer's disease: Overexpression paradigm versus knockin paradigm

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Integrative Analysis of Hippocampus Gene Expression Profiles Identifies Network Alterations in Aging and Alzheimer’s Disease

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Oxidative species-induced excitonic transport in tubulin aromatic networks: Potential implications for neurodegenerative disease

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Exploring the new horizons of drug repurposing: A vital tool for turning hard work into smart work

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Reduced number of axonal mitochondria and tau hypophosphorylation in mouse P301L tau knockin neurons

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Molecular Insights into the Pathogenesis of Alzheimer's Disease and Its Relationship to Normal Aging

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The Protein Phosphatase PP2A/Bα Binds to the Microtubule-associated Proteins Tau and MAP2 at a Motif Also Recognized by the Kinase Fyn

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SUMO-1 immunoreactivity co-localizes with phospho-Tau in APP transgenic mice but not in mutant Tau transgenic mice

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p53 prevents neurodegeneration by regulating synaptic genes

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Accumulation of tumor-suppressor PTEN in Alzheimer neurofibrillary tangles

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Potential mechanisms and implications for the formation of tau oligomeric strains

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Maturation of neuronal AD-tau pathology involves site-specific phosphorylation of cytoplasmic and synaptic tau preceding conformational change and fibril formation

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Human Tau Isoforms and Proteolysis for Production of Toxic Tau Fragments in Neurodegeneration

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Structural mechanism for specific binding of chemical compounds to amyloid fibrils

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Tau mutants bind tubulin heterodimers with enhanced affinity

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Tau deletion exacerbates the phenotype of Niemann–Pick type C mice and implicates autophagy in pathogenesis

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Potential of the Antibody Against cis–Phosphorylated Tau in the Early Diagnosis, Treatment, and Prevention of Alzheimer Disease and Brain Injury

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Liquid–Liquid Phase Separation of Tau Protein Is Encoded at the Monomeric Level

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Endoplasmic reticulum: The unfolded protein response is tangled in neurodegeneration

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Cathepsin D regulates cerebral Aβ42/40 ratios via differential degradation of Aβ42 and Aβ40

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Characterization of tau fibrillization in vitro

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Endogenous Aβ causes cell death via early tau hyperphosphorylation

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Quinolone–benzylpiperidine derivatives as novel acetylcholinesterase inhibitor and antioxidant hybrids for Alzheimer Disease

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In vivo measurement of glutamate loss is associated with synapse loss in a mouse model of tauopathy

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Extracellular Tau Oligomers Induce Invasion of Endogenous Tau into the Somatodendritic Compartment and Axonal Transport Dysfunction

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A Nanoplasmonic Biosensor for Ultrasensitive Detection of Alzheimer’s Disease Biomarker Using a Chaotropic Agent

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A DNA damage-activated checkpoint kinase phosphorylates tau and enhances tau-induced neurodegeneration

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A critical appraisal of tau‐targeting therapies for primary and secondary tauopathies

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Membrane trafficking in neuronal maintenance and degeneration

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Isomerase Pin1 Stimulates Dephosphorylation of Tau Protein at Cyclin-dependent Kinase (Cdk5)-dependent Alzheimer Phosphorylation Sites

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Tau‐Induced Traffic Jams Reflect Organelles Accumulation at Points of Microtubule Polar Mismatching

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l -Theanine attenuates cadmium-induced neurotoxicity through the inhibition of oxidative damage and tau hyperphosphorylation

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Alzheimer’s Disease and ncRNAs

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Cerebrospinal Fluid Biomarkers in Cerebral Amyloid Angiopathy

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Toxic Tau Oligomers Modulated by Novel Curcumin Derivatives

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Droplet Microfluidic System with On-Demand Trapping and Releasing of Droplet for Drug Screening Applications

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Imaging mass spectrometry (IMS) of cortical lipids from preclinical to severe stages of Alzheimer's disease

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Cellular and regional vulnerability in frontotemporal tauopathies

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Dysregulated Wnt Signalling in the Alzheimer’s Brain

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Protective effects of ginsenoside Rd against okadaic acid-induced neurotoxicity in vivo and in vitro

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Age-related decline in white matter integrity in a mouse model of tauopathy: an in vivo diffusion tensor magnetic resonance imaging study

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Rosmarinic acid- and curcumin-loaded polyacrylamide-cardiolipin-poly(lactide-co-glycolide) nanoparticles with conjugated 83-14 monoclonal antibody to protect β-amyloid-insulted neurons

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Gut microbiota modulation in Alzheimer's disease: Focus on lipid metabolism

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UBE4B, a microRNA-9 target gene, promotes autophagy-mediated Tau degradation

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Necrostatin-1 inhibits the degeneration of neural cells induced by aluminum exposure

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14-3-3 Proteins and regulation of cytoskeleton

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Evidence for the Existence of a Secondary Pathway for Fibril Growth during the Aggregation of Tau

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Phosphoregulation of Tau modulates inhibition of kinesin-1 motility

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Alzheimer’s Disease – Future Therapy Based on Dendrimers

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The role of inflammatory processes in Alzheimer’s disease

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Design and Synthesis of Skeletal Analogues of Gambierol: Attenuation of Amyloid-β and Tau Pathology with Voltage-Gated Potassium Channel andN-Methyl- d -aspartate Receptor Implications

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Melatonin ameliorates tau-related pathology via the miR-504-3p and CDK5 axis in Alzheimer’s disease

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High Resolution Discovery Proteomics Reveals Candidate Disease Progression Markers of Alzheimer’s Disease in Human Cerebrospinal Fluid

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Microtubule Binding and Trapping at the Tip of Neurites Regulate Tau Motion in Living Neurons

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Where Vision Meets Memory: Prefrontal–Posterior Networks for Visual Object Constancy during Categorization and Recognition

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Sodium selenate, a protein phosphatase 2A activator, mitigates hyperphosphorylated tau and improves repeated mild traumatic brain injury outcomes

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High–Molecular-Weight Paired Helical Filaments from Alzheimer Brain Induces Seeding of Wild-Type Mouse Tau into an Argyrophilic 4R Tau Pathology in Vivo

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