Pathophysiology of the brain extracellular matrix: a new target for remyelination

How Matrix Metalloproteinases Regulate Cell Behavior

Sternlicht, M. D., & Werb, Z. (2001) · Annual Review of Cell and Developmental Biology · doi:10.1146/annurev.cellbio.17.1.463 · Cited by 3,959 · see citing works

Regeneration beyond the glial scar

Silver, J., & Miller, J. H. (2004) · Nature reviews. Neuroscience · doi:10.1038/nrn1326 · Cited by 3,090 · see citing works

Chondroitinase ABC promotes functional recovery after spinal cord injury

Bradbury, E. J., Moon, L. D. F., Popat, R. J., King, V. R., Bennett, G. S., Patel, P. N., Fawcett, J. W., & McMahon, S. B. (2002) · Nature · doi:10.1038/416636a · Cited by 2,357 · see citing works

Glial inhibition of CNS axon regeneration

Yiu, G. C., & He, Z. (2006) · Nature reviews. Neuroscience · doi:10.1038/nrn1956 · Cited by 1,500 · see citing works

Reduction of neurite outgrowth in a model of glial scarring following CNS injury is correlated with the expression of inhibitory molecules on reactive astrocytes

McKeon, R., Schreiber, R., Rudge, J., & Silver, J. (1991) · The Journal of Neuroscience · doi:10.1523/jneurosci.11-11-03398.1991 · Cited by 1,188 · see citing works

Carcinoma-produced factors activate myeloid cells through TLR2 to stimulate metastasis

Kim, S., Takahashi, H., Lin, W.-W., Descargues, P., Grivennikov, S., Kim, Y., Luo, J.-L., & Karin, M. (2009) · Nature · doi:10.1038/nature07623 · Cited by 1,100 · see citing works

CNS injury, glial scars, and inflammation: Inhibitory extracellular matrices and regeneration failure

Fitch, M. T., & Silver, J. (2008) · Experimental Neurology · doi:10.1016/j.expneurol.2007.05.014 · Cited by 1,007 · see citing works

The impact of the extracellular matrix on inflammation

Sorokin, L. (2010) · Nature reviews. Immunology · doi:10.1038/nri2852 · Cited by 918 · see citing works

Differentiation block of oligodendroglial progenitor cells as a cause for remyelination failure in chronic multiple sclerosis

Kuhlmann, T., Miron, V., Cuo, Q., Wegner, C., Antel, J., & Bruck, W. (2008) · Brain · doi:10.1093/brain/awn096 · Cited by 864 · see citing works

PTPσ Is a Receptor for Chondroitin Sulfate Proteoglycan, an Inhibitor of Neural Regeneration

Shen, Y., Tenney, A. P., Busch, S. A., Horn, K. P., Cuascut, F. X., Liu, K., He, Z., Silver, J., & Flanagan, J. G. (2009) · Science · doi:10.1126/science.1178310 · Cited by 682 · see citing works

Matrix metalloproteinases and diseases of the CNS

Yong, V. W., Forsyth, P. A., Bell, R. B., Krekoski, C. A., & Edwards, D. R. (1998) · Trends in Neurosciences · doi:10.1016/s0166-2236(97)01169-7 · Cited by 635 · see citing works

Proteoglycans in the Developing Brain: New Conceptual Insights for Old Proteins

Bandtlow, C. E., & Zimmermann, D. R. (2000) · Physiological Reviews · doi:10.1152/physrev.2000.80.4.1267 · Cited by 632 · see citing works

Hyaluronan accumulates in demyelinated lesions and inhibits oligodendrocyte progenitor maturation

Back, S. A., Tuohy, T. M. F., Chen, H., Wallingford, N., Craig, A., Struve, J., Luo, N. L., Banine, F., Liu, Y., Chang, A., et al. (2005) · Nature Medicine · doi:10.1038/nm1279 · Cited by 612 · see citing works

Metalloproteinases: Mediators of Pathology and Regeneration in the CNS

Yong, V. W. (2005) · Nature Reviews Neuroscience · doi:10.1038/nrn1807 · Cited by 582 · see citing works

The role of chondroitin sulfate proteoglycans in regeneration and plasticity in the central nervous system

Galtrey, C. M., & Fawcett, J. W. (2007) · Brain Research Reviews · doi:10.1016/j.brainresrev.2006.09.006 · Cited by 575 · see citing works

Extracellular matrix molecules and synaptic plasticity

Dityatev, A., & Schachner, M. (2003) · Nature Reviews Neuroscience · doi:10.1038/nrn1115 · Cited by 564 · see citing works

Matrix metalloproteinases: What do they not do? New substrates and biological roles identified by murine models and proteomics

Rodrı́guez, D., Morrison, C., & Overall, C. M. (2009) · Biochimica et Biophysica Acta (BBA) - Molecular Cell Research · doi:10.1016/j.bbamcr.2009.09.015 · Cited by 560 · see citing works

The chondroitin sulfate proteoglycans neurocan, brevican, phosphacan, and versican are differentially regulated following spinal cord injury

Jones, L. L., Margolis, R. U., & Tuszynski, M. H. (2003) · Experimental Neurology · doi:10.1016/s0014-4886(03)00087-6 · Cited by 545 · see citing works

Microregional extracellular matrix heterogeneity in brain modulates glioma cell invasion

Bellail, A. C., HUNTER, S. B., Brat, D. J., Tan, C., & Meir, E. G. V. (2004) · The International Journal of Biochemistry & Cell Biology · doi:10.1016/j.biocel.2004.01.013 · Cited by 527 · see citing works

A Disintegrin-like and Metalloprotease (Reprolysin-type) with Thrombospondin Type 1 Motif (ADAMTS) Superfamily: Functions and Mechanisms

Apte, S. (2009) · Journal of Biological Chemistry · doi:10.1074/jbc.r109.052340 · Cited by 506 · see citing works

NgR1 and NgR3 are receptors for chondroitin sulfate proteoglycans

Dickendesher, T. L., Baldwin, K. T., Mironova, Y. A., Koriyama, Y., Raiker, S. J., Askew, K. L., Wood, A., Geoffroy, C. G., Zheng, B., Liepmann, C. D., et al. (2012) · Nature Neuroscience · doi:10.1038/nn.3070 · Cited by 449 · see citing works

Extracellular matrix and perineuronal nets in CNS repair

Kwok, J. C. F., Dick, G., Wang, D., & Fawcett, J. W. (2011) · Developmental Neurobiology · doi:10.1002/dneu.20974 · Cited by 395 · see citing works

Development of the blood-brain barrier

Engelhardt, B. (2003) · Cell and Tissue Research · doi:10.1007/s00441-003-0751-z · Cited by 377 · see citing works

Reactive Astrocytes As Therapeutic Targets for CNS Disorders

Hamby, M. E., & Sofroniew, M. V. (2010) · Neurotherapeutics · doi:10.1016/j.nurt.2010.07.003 · Cited by 367 · see citing works

EGFR Activation Mediates Inhibition of Axon Regeneration by Myelin and Chondroitin Sulfate Proteoglycans

Koprivica, V., Cho, K., Park, J. B., Yiu, G. C., Atwal, J. K., Gore, B. B., Kim, J. A., Lin, E., Tessier‐Lavigne, M., Chen, D. F., et al. (2005) · Science · doi:10.1126/science.1115462 · Cited by 363 · see citing works

Leukocyte common antigen-related phosphatase is a functional receptor for chondroitin sulfate proteoglycan axon growth inhibitors

Fisher, D., Xing, B., Dill, J., Li, H., Hoang, H. H., Zhao, Z., Yang, X.-L., Bachoo, R., Cannon, S., Longo, F. M., et al. (2011) · The Journal of Neuroscience · doi:10.1523/jneurosci.1737-11.2011 · Cited by 312 · see citing works

Cellular signaling by neural cell adhesion molecules of the immunoglobulin superfamily

Crossin, K. L., & Krushel, L. A. (2000) · Developmental Dynamics · doi:10.1002/(sici)1097-0177(200006)218:2 · Cited by 283 · see citing works

Chondroitin/dermatan sulfate in the central nervous system

Sugahara, K., & Mikami, T. (2007) · Current Opinion in Structural Biology · doi:10.1016/j.sbi.2007.08.015 · Cited by 275 · see citing works

Two Faces of Chondroitin Sulfate Proteoglycan in Spinal Cord Repair: A Role in Microglia/Macrophage Activation

Rolls, A., Shechter, R., London, A., Segev, Y., Jacob–Hirsch, J., Amariglio, N., Rechavi, G., & Schwartz, M. (2008) · PLoS Medicine · doi:10.1371/journal.pmed.0050171 · Cited by 272 · see citing works

Neuronal matrix metalloproteinase-2 degrades and inactivates a neurite-inhibiting chondroitin sulfate proteoglycan

Zuo, J., Ferguson, T. A., Hernandez, Y. J., Stetler-Stevenson, W. G., & Muir, D. (1998) · The Journal of Neuroscience · doi:10.1523/jneurosci.18-14-05203.1998 · Cited by 270 · see citing works

Differentiation of proliferated NG2-positive glial progenitor cells in a remyelinating lesion

Watanabe, M., Toyama, Y., & Nishiyama, A. (2002) · Journal of Neuroscience Research · doi:10.1002/jnr.10338 · Cited by 261 · see citing works

Matrix Metalloproteinase-9 Facilitates Remyelination in Part by Processing the Inhibitory NG2 Proteoglycan

Larsen, P. H., Wells, J. E. A., Stallcup, W. B., Opdenakker, G., & Yong, V. W. (2003) · Journal of Neuroscience · doi:10.1523/jneurosci.23-35-11127.2003 · Cited by 260 · see citing works

Chondroitin sulfate proteoglycans in demyelinated lesions impair remyelination

Lau, L. W., Keough, M. B., Haylock‐Jacobs, S., Cua, R., Döring, A., Sloka, S., Stirling, D. P., Rivest, S., & Yong, V. W. (2012) · Annals of Neurology · doi:10.1002/ana.23599 · Cited by 248 · see citing works

Matrix Metalloproteinase-2 Facilitates Wound Healing Events That Promote Functional Recovery after Spinal Cord Injury

Hsu, J.-Y. C., McKeon, R. J., Goussev, S., Werb, Z., Lee, J.-U., Trivedi, A. A., & Noble‐Haeusslein, L. J. (2006) · Journal of Neuroscience · doi:10.1523/jneurosci.1993-06.2006 · Cited by 232 · see citing works

Hyaluronic acid and hyaluronic acid-binding proteins in brain extracellular matrix

Bignami, A., Hosley, M., & Dahl, D. R. (1993) · Anatomy and Embryology · doi:10.1007/bf00190136 · Cited by 224 · see citing works

Laminin-2/integrin interactions enhance myelin membrane formation by oligodendrocytes.

Buttery, P., & ffrench-Constant, C. (1999) · Molecular and cellular neurosciences · doi:10.1006/mcne.1999.0781 · Cited by 217 · see citing works

Cortical remyelination: A new target for repair therapies in multiple sclerosis

Chang, A., Staugaitis, S. M., Dutta, R., Batt, C. E., Easley, K. E., Chomyk, A. M., Yong, V. W., Fox, R. J., Kidd, G. J., & Trapp, B. D. (2012) · Annals of Neurology · doi:10.1002/ana.23693 · Cited by 216 · see citing works

Fibronectin aggregation in multiple sclerosis lesions impairs remyelination

Stoffels, J. M. J., de Jonge, J. C., Stancic, M., Nomden, A., van Strien, M. E., Ma, D., Šišková, Z., Maier, O., ffrench‐Constant, C., Franklin, R. J. M., et al. (2013) · Brain · doi:10.1093/brain/aws313 · Cited by 206 · see citing works

Developing inhibitors of glycan processing enzymes as tools for enabling glycobiology

Gloster, T. M., & Vocadlo, D. J. (2012) · Nature Chemical Biology · doi:10.1038/nchembio.1029 · Cited by 195 · see citing works

Scar-mediated inhibition and CSPG receptors in the CNS

Sharma, K., Selzer, M. E., & Li, S. (2012) · Experimental Neurology · doi:10.1016/j.expneurol.2012.07.009 · Cited by 189 · see citing works

A Novel DNA Enzyme Reduces Glycosaminoglycan Chains in the Glial Scar and Allows Microtransplanted Dorsal Root Ganglia Axons to Regenerate beyond Lesions in the Spinal Cord

Grimpe, B., & Silver, J. (2004) · Journal of Neuroscience · doi:10.1523/jneurosci.4986-03.2004 · Cited by 184 · see citing works

Integrin-linked kinase is required for laminin-2–induced oligodendrocyte cell spreading and CNS myelination

Chun, S. J., Rasband, M. N., Sidman, R. L., Habib, A. A., & Vartanian, T. (2003) · The Journal of Cell Biology · doi:10.1083/jcb.200304154 · Cited by 170 · see citing works

CS-4,6 is differentially upregulated in glial scar and is a potent inhibitor of neurite extension

Gilbert, R. J., McKeon, R. J., Darr, A., Calabro, A. R., Hascall, V., & Bellamkonda, R. V. (2005) · Molecular and Cellular Neuroscience · doi:10.1016/j.mcn.2005.04.006 · Cited by 168 · see citing works

White Matter Extracellular Matrix Chondroitin Sulfate/Dermatan Sulfate Proteoglycans in Multiple Sclerosis

Sobel, R. A., & Ahmed, A. S. (2001) · Journal of Neuropathology & Experimental Neurology · doi:10.1093/jnen/60.12.1198 · Cited by 167 · see citing works

Integrin activation promotes axon growth on inhibitory chondroitin sulfate proteoglycans by enhancing integrin signaling

Tan, C. L., Kwok, J. C. F., Patani, R., ffrench-Constant, C., Chandran, S., & Fawcett, J. W. (2011) · The Journal of Neuroscience · doi:10.1523/jneurosci.0008-11.2011 · Cited by 160 · see citing works

Extracellular Matrix in Multiple Sclerosis Lesions: Fibrillar Collagens, Biglycan and Decorin are Upregulated and Associated with Infiltrating Immune Cells

Mohan, H., Krumbholz, M., Sharma, R. D., Eisele, S. C., Junker, A., Sixt, M., Newcombe, J., Wekerle, H., Hohlfeld, R., Lassmann, H., et al. (2010) · Brain Pathology · doi:10.1111/j.1750-3639.2010.00399.x · Cited by 160 · see citing works

The inhibitory effects of chondroitin sulfate proteoglycans on oligodendrocytes

Siebert, J. R., & Osterhout, D. J. (2011) · Journal of Neurochemistry · doi:10.1111/j.1471-4159.2011.07370.x · Cited by 158 · see citing works

A sulfated carbohydrate epitope inhibits axon regeneration after injury

Brown, J. M., Xia, J., Zhuang, B., Cho, K.-S., Rogers, C. J., Gama, C. I., Rawat, M., Tully, S. E., Uetani, N., Mason, D. E., et al. (2012) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1121318109 · Cited by 154 · see citing works

The perineuronal net component of the extracellular matrix in plasticity and epilepsy

McRae, P. A., & Porter, B. E. (2012) · Neurochemistry International · doi:10.1016/j.neuint.2012.08.007 · Cited by 143 · see citing works

Chondroitin sulfate proteoglycans inhibit oligodendrocyte myelination through PTPσ

Pendleton, J. C., Shamblott, M. J., Gary, D. S., Belegu, V., Hurtado, A., Malone, M. L., & McDonald, J. W. (2013) · Experimental Neurology · doi:10.1016/j.expneurol.2013.04.003 · Cited by 134 · see citing works

Chondroitinase and Growth Factors Enhance Activation and Oligodendrocyte Differentiation of Endogenous Neural Precursor Cells after Spinal Cord Injury

Karimi‐Abdolrezaee, S., Schut, D., Wang, J., & Fehlings, M. G. (2012) · PLoS ONE · doi:10.1371/journal.pone.0037589 · Cited by 126 · see citing works

Embryonic Neurons Adapt to the Inhibitory Proteoglycan Aggrecan by Increasing Integrin Expression

Condic, M. L., Snow, D. M., & Letourneau, P. C. (1999) · Journal of Neuroscience · doi:10.1523/jneurosci.19-22-10036.1999 · Cited by 123 · see citing works

Bral1: its role in diffusion barrier formation and conduction velocity in the CNS

Bekku, Y., Vargová, L., Goto, Y., Vorísek, I., Dmytrenko, L., Narasaki, M., Ohtsuka, A., Fässler, R., Ninomiya, Y., Syková, E., et al. (2010) · The Journal of Neuroscience · doi:10.1523/jneurosci.5598-09.2010 · Cited by 123 · see citing works

6-Sulphated Chondroitins Have a Positive Influence on Axonal Regeneration

Lin, R., Rosahl, T. W., Whiting, P. J., Fawcett, J. W., & Kwok, J. C. F. (2011) · PLoS ONE · doi:10.1371/journal.pone.0021499 · Cited by 121 · see citing works

Extensive extracellular matrix depositions in active multiple sclerosis lesions.

van Horssen, J., Bö, L., Dijkstra, C. D., & de Vries, H. E. (2006) · Neurobiology of Disease · doi:10.1016/j.nbd.2006.08.005 · Cited by 119 · see citing works

Inhibiting Glycosaminoglycan Chain Polymerization Decreases the Inhibitory Activity of Astrocyte-Derived Chondroitin Sulfate Proteoglycans

Laabs, T. L., Wang, H., Katagiri, Y., McCann, T. E., Fawcett, J. W., & Geller, H. M. (2007) · Journal of Neuroscience · doi:10.1523/jneurosci.2807-07.2007 · Cited by 117 · see citing works

A ‘GAG’ reflex prevents repair of the damaged CNS

Sherman, L. S., & Back, S. A. (2008) · Trends in Neurosciences · doi:10.1016/j.tins.2007.11.001 · Cited by 116 · see citing works

The extracellular matrix in multiple sclerosis pathology

van Horssen, J., Dijkstra, C. D., & de Vries, H. E. (2007) · Journal of Neurochemistry · doi:10.1111/j.1471-4159.2007.04897.x · Cited by 112 · see citing works

Critical role of microvasculature basal lamina in ischemic brain injury

Wang, C. X., & Shuaib, A. M. (2007) · Progress in Neurobiology · doi:10.1016/j.pneurobio.2007.07.006 · Cited by 111 · see citing works

Digestion products of the PH20 hyaluronidase inhibit remyelination

Preston, M., Gong, X., Su, W., Matsumoto, S. G., Banine, F., Winkler, C., Foster, S., Xing, R., Struve, J., Dean, J., et al. (2013) · Annals of Neurology · doi:10.1002/ana.23788 · Cited by 107 · see citing works

GROWTH CONE BEHAVIOR IN THE PRESENCE OF SOLUBLE CHONDROITIN SULFATE PROTEOGLYCAN (CSPG), COMPARED TO BEHAVIOR ON CSPG BOUND TO LAMININ OR FIBRONECTIN

Snow, D. M., Brown, E. M., & Letourneau, P. C. (1996) · International Journal of Developmental Neuroscience · doi:10.1016/0736-5748(96)00017-2 · Cited by 103 · see citing works

The endogenous proteoglycan-degrading enzyme ADAMTS-4 promotes functional recovery after spinal cord injury

Tauchi, R., Imagama, S., Natori, T., Ohgomori, T., Muramoto, A., Shinjo, R., Matsuyama, Y., Ishiguro, N., & Kadomatsu, K. (2012) · Journal of Neuroinflammation · doi:10.1186/1742-2094-9-53 · Cited by 91 · see citing works

Chondroitinase treatment following spinal contusion injury increases migration of oligodendrocyte progenitor cells

Siebert, J. R., Stelzner, D. J., & Osterhout, D. J. (2011) · Experimental Neurology · doi:10.1016/j.expneurol.2011.05.002 · Cited by 89 · see citing works

Brain matrix: structure, turnover and necessity

Rauch, U. (2007) · Biochemical Society Transactions · doi:10.1042/bst0350656 · Cited by 88 · see citing works

Laminin regulates postnatal oligodendrocyte production by promoting oligodendrocyte progenitor survival in the subventricular zone

Relucio, J. L. V., Menezes, M. J., Miyagoe‐Suzuki, Y., Takeda, S., & Colognato, H. (2012) · Glia · doi:10.1002/glia.22365 · Cited by 87 · see citing works

Human diseases reveal novel roles for neural laminins

Colognato, H., ffrench‐Constant, C., & Feltri, M. L. (2005) · Trends in Neurosciences · doi:10.1016/j.tins.2005.07.004 · Cited by 85 · see citing works

Reduced inflammation accompanies diminished myelin damage and repair in the NG2 null mouse spinal cord

Kuchárová, K., Chang, Y., Boor, A., Yong, V. W., & Stallcup, W. B. (2011) · Journal of Neuroinflammation · doi:10.1186/1742-2094-8-158 · Cited by 76 · see citing works

Fibronectin impedes “myelin” sheet-directed flow in oligodendrocytes: A role for a beta 1 integrin-mediated PKC signaling pathway in vesicular trafficking

Šišková, Z., Baron, W., de Vries, H., et al. (2006) · Molecular and Cellular Neuroscience · doi:10.1016/j.mcn.2006.07.001 · Cited by 75 · see citing works

Brain extracellular space fixed for electron microscopy

Cragg, B. G. (1979) · Neuroscience Letters · doi:10.1016/0304-3940(79)96130-5 · Cited by 71 · see citing works

Recovery from spinal cord injury: A new transection model in the C57Bl/6 mouse

Seitz, A., Aglow, E., & Heber‐Katz, E. (2002) · Journal of Neuroscience Research · doi:10.1002/jnr.10098 · Cited by 59 · see citing works

Targeted downregulation of N‐acetylgalactosamine 4‐sulfate 6‐O‐sulfotransferase significantly mitigates chondroitin sulfate proteoglycan‐mediated inhibition

Karumbaiah, L., Anand, S., Thazhath, R., Zhong, Y., McKeon, R. J., & Bellamkonda, R. V. (2011) · Glia · doi:10.1002/glia.21170 · Cited by 52 · see citing works

Actomyosin contractility controls cell surface area of oligodendrocytes

Kippert, A., Fitzner, D., Helenius, J. H., & Simons, M. (2009) · BMC Cell Biology · doi:10.1186/1471-2121-10-71 · Cited by 51 · see citing works

Activated astrocytes induce nitric oxide synthase-2 in cerebral endothelium via tumor necrosis factor ?

Shafer, R. A., & Murphy, S. P. (1997) · Glia · doi:10.1002/(sici)1098-1136(199712)21:4 · Cited by 51 · see citing works

Elevated matrix metalloproteinase-9 and degradation of perineuronal nets in cerebrocortical multiple sclerosis plaques

Gray, E., Thomas, T. L., Betmouni, S., Scolding, N., & Love, S. (2008) · Journal of Neuropathology & Experimental Neurology · doi:10.1097/nen.0b013e318183d003 · Cited by 51 · see citing works

Roles of the Telencephalic Cells and their Chondroitin Sulfate Proteoglycans in Delimiting an Anterior Border of the Retinal Pathway

Ichijo, H., & Kawabata, I. (2001) · Journal of Neuroscience · doi:10.1523/jneurosci.21-23-09304.2001 · Cited by 49 · see citing works

Fibronectin attenuates process outgrowth in oligodendrocytes by mislocalizing MMP-9 activity

Šišková, Z., Yong, V. W., Nomden, A., van Strien, M. E., Hoekstra, D., & Baron, W. (2009) · Molecular and Cellular Neuroscience · doi:10.1016/j.mcn.2009.07.005 · Cited by 48 · see citing works

Expression and Effects of Hyaluronan and of the Hyaluronan‐Binding Protein Hyaluronectin in Newborn Rat Brain Glial Cell Cultures

Marret, S., Delpech, B., DELPECH, A., Asou, H., Girard, N., Courel, M., Chauzy, C., Maingonnat, C., & Fessard, C. (1994) · Journal of Neurochemistry · doi:10.1046/j.1471-4159.1994.62041285.x · Cited by 42 · see citing works

Alzheimer s disease and heparan sulfate proteoglycan

Fukuchi, K.-I. (1998) · Frontiers in bioscience · doi:10.2741/a277 · Cited by 34 · see citing works

Transplantation of Fibroblasts that Overexpress Matrix Metalloproteinase-3 into the Site of Spinal Cord Injury in Rats

Pizzi, M. A., & Crowe, M. J. (2006) · Journal of Neurotrauma · doi:10.1089/neu.2006.23.1750 · Cited by 24 · see citing works

Untitled work

Meyer-Puttlitz (1996) · doi:10.1002/(sici)1096-9861(19960226)366:1

Extracellular Matrix Assembly: A Multiscale Deconstruction

Mouw, J. K., Ou, G., & Weaver, V. M. (2014) · Nature Reviews Molecular Cell Biology · doi:10.1038/nrm3902 · Cited by 1,534 · see citing works

Regenerating CNS myelin — from mechanisms to experimental medicines

Franklin, R. J. M., & ffrench-Constant, C. (2017) · Nature Reviews Neuroscience · doi:10.1038/nrn.2017.136 · Cited by 647 · see citing works

Engineered In Vitro Disease Models

Benam, K. H., Dauth, S., Hassell, B., Herland, A., Jain, A., Jang, K.-J., Karalis, K., Kim, H. J., MacQueen, L., Mahmoodian, R., et al. (2015) · Annual Review of Pathology: Mechanisms of Disease · doi:10.1146/annurev-pathol-012414-040418 · Cited by 554 · see citing works

Progressive multiple sclerosis: from pathophysiology to therapeutic strategies

Faissner, S., Plemel, J. R., Gold, R., & Yong, V. W. (2019) · Nature Reviews Drug Discovery · doi:10.1038/s41573-019-0035-2 · Cited by 459 · see citing works

Psychedelics reopen the social reward learning critical period

Nardou, R., Sawyer, E., Song, Y. J., Wilkinson, M., Padovan-Hernandez, Y., de Deus, J. L., Wright, N., Lama, C., Faltin, S., Goff, L. A., et al. (2023) · Nature · doi:10.1038/s41586-023-06204-3 · Cited by 358 · see citing works

Perineuronal nets and schizophrenia: The importance of neuronal coatings

Bitanihirwe, B. K. Y., & Woo, T.-U. W. (2014) · Neuroscience & Biobehavioral Reviews · doi:10.1016/j.neubiorev.2014.03.018 · Cited by 95 · see citing works

<b>Psychopathological manifestations of joint hypermobility and joint hypermobility syndrome/ Ehlers–Danlos syndrome, hypermobility type:</b> The link between connective tissue and psychological distress revised

Sinibaldi, L., Ursini, G., & Castori, M. (2015) · American Journal of Medical Genetics Part C: Seminars in Medical Genetics · doi:10.1002/ajmg.c.31430 · Cited by 87 · see citing works

Light reintroduction after dark exposure reactivates plasticity in adults via perisynaptic activation of MMP-9

Murase, S., Lantz, C. L., & Quinlan, E. M. (2017) · eLife · doi:10.7554/elife.27345 · Cited by 87 · see citing works

Chondroitin sulfate glycosaminoglycan hydrogels create endogenous niches for neural stem cells

Karumbaiah, L., Enam, S. F., Brown, A. C., Saxena, T., Betancur, M. I., Barker, T. H., & Bellamkonda, R. V. (2015) · Bioconjugate Chemistry · doi:10.1021/acs.bioconjchem.5b00397 · Cited by 73 · see citing works

Fibrotic scar after experimental autoimmune encephalomyelitis inhibits oligodendrocyte differentiation.

Yahn, S. L., Li, J., Goo, I., Gao, H., Brambilla, R., & Lee, J. K. (2020) · Neurobiology of Disease · doi:10.1016/j.nbd.2019.104674 · Cited by 45 · see citing works

Differential Effects of Heparin and Hyaluronic Acid on Neural Patterning of Human Induced Pluripotent Stem Cells

Bejoy, J., Wang, Z., Bijonowski, B., Yang, M., Ma, T., Sang, Q.-X., & Li, Y. (2018) · ACS Biomaterials Science &amp; Engineering · doi:10.1021/acsbiomaterials.8b01142 · Cited by 46 · see citing works

Peripheral immune-derived matrix metalloproteinase promotes stress susceptibility

Russo, S., Cathomas, F., Lin, H.-Y., Chan, K., Li, L., Durand-de Cuttoli, R., Parise, L., Aubry, A., Muhareb, S., Desland, F., et al. (2023) · doi:10.21203/rs.3.rs-1647827/v1 · Cited by 189 · see citing works

Myelin inhibits oligodendroglial maturation and regulates oligodendrocytic transcription factor expression

Plemel, J. R., Manesh, S. B., Sparling, J. S., & Tetzlaff, W. (2013) · Glia · doi:10.1002/glia.22535 · Cited by 107 · see citing works

The orphan G protein‐coupled receptor GPR149 is a negative regulator of myelination and remyelination

Suo, N., He, B., Cui, S.-H., Yang, Y., Wang, M., Yuan, Q., & Xie, X. (2022) · Glia · doi:10.1002/glia.24233 · Cited by 15 · see citing works

Chondroitin sulfate proteoglycan form of cellular and cell-surface Alzheimer amyloid precursor

Shioi, J., Refolo, L. M., Efthimiopoulos, S., & Robakis, N. K. R. K. (1993) · Neuroscience Letters · doi:10.1016/0304-3940(93)90186-o · Cited by 25 · see citing works

Construction of perineuronal net-like structure by cortical neurons in culture

Miyata, S., Nishimura, Y., Hayashi, N., & Oohira, A. (2005) · Neuroscience · doi:10.1016/j.neuroscience.2005.07.031 · Cited by 75 · see citing works

Traumatic brain injury results in disparate regions of chondroitin sulfate proteoglycan expression that are temporally limited

Harris, N. G., Carmichael, S. T., Hovda, D. A., & Sutton, R. L. (2009) · Journal of Neuroscience Research · doi:10.1002/jnr.22115 · Cited by 62 · see citing works