Cellular and epigenetic drivers of stem cell ageing

Translating the Histone Code

Jenuwein, T., & Allis, C. D. (2001) · Science · doi:10.1126/science.1063127 · Cited by 9,756

Shedding light on the cell biology of extracellular vesicles

van Niel, G., D'Angelo, G., & Raposo, G. (2018) · Nature Reviews Molecular Cell Biology · doi:10.1038/nrm.2017.125 · Cited by 8,369

A comparison of normalization methods for high density oligonucleotide array data based on variance and bias

Bolstad, B. M., Irizarry, R. A., Åstrand, M., & Speed, T. P. (2003) · Bioinformatics · doi:10.1093/bioinformatics/19.2.185 · Cited by 8,328

DNA methylation age of human tissues and cell types

Horvath, S. (2013) · Genome Biology · doi:10.1186/gb-2013-14-10-r115 · Cited by 7,075

Notch Signaling: Cell Fate Control and Signal Integration in Development

Artavanis-Tsakonas, S., Rand, M. D., & Lake, R. J. (1999) · Science · doi:10.1126/science.284.5415.770 · Cited by 5,909

Wnt/β-Catenin Signaling in Development and Disease

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The Wnt Signaling Pathway in Development and Disease

Logan, C. Y., & Nusse, R. (2004) · Annual Review of Cell and Developmental Biology · doi:10.1146/annurev.cellbio.20.010403.113126 · Cited by 5,325

Age-related clonal hematopoiesis associated with adverse outcomes

Jaiswal, S., Fontanillas, P., Flannick, J., Manning, A., Grauman, P. V., Mar, B. G., Lindsley, R. C., Mermel, C. H., Burtt, N., Chavez, A., et al. (2014) · New England Journal of Medicine · doi:10.1056/nejmoa1408617 · Cited by 4,841

Chronic Inflammation (Inflammaging) and Its Potential Contribution to Age-Associated Diseases

Franceschi, C., & Campisi, J. (2014) · The Journals of Gerontology Series A: Biological Sciences and Medical Sciences · doi:10.1093/gerona/glu057 · Cited by 3,891

Clonal hematopoiesis and blood-cancer risk inferred from blood DNA sequence

Genovese, G., Kähler, A. K., Handsaker, R. E., Lindberg, J., Rose, S. A., Bakhoum, S. F., Chambert, K., Mick, E., Neale, B. M., Fromer, M., et al. (2014) · New England Journal of Medicine · doi:10.1056/nejmoa1409405 · Cited by 3,531

3D spheroid culture synchronizes heterogeneous MSCs into an immunomodulatory phenotype with enhanced anti-inflammatory effects

Lu, R., Zheng, K., Zhou, Y., Wang, W., Zhang, Y., Chen, Y., Mo, M., Li, X., Dong, Y., Xie, J., et al. (2024) · iScience · doi:10.1016/j.isci.2024.110811 · Cited by 21

Aberrant Neurogliovascular Unit Dynamics in Cerebral Small Vessel Disease: A Rheological Clue to Vascular Parkinsonism

Nassir, C. M. N. C. M., Damodaran, T. K., Yusof, S. R., Norazit, A., Chilla, G. S. V. N., Huen, I., Nagaraja, B. P. K., Ibrahim, N. M., & Mustapha, M. (2021) · Pharmaceutics · doi:10.3390/pharmaceutics13081207 · Cited by 22

LIN28A enhances regenerative capacity of human somatic tissue stem cells via metabolic and mitochondrial reprogramming

Pieknell, K., Sulistio, Y. A., Wulansari, N., Darsono, W. H. W., Chang, M., Ko, J., Chang, J. W., Kim, M., Lee, M. R., Lee, S. A., et al. (2021) · Cell Death and Differentiation · doi:10.1038/s41418-021-00873-1 · Cited by 21

Germline stem cell aging in the Drosophila ovary

Ishibashi, J. R., Taslim, T. H., & Ruohola‐Baker, H. (2020) · Current Opinion in Insect Science · doi:10.1016/j.cois.2019.11.003 · Cited by 20

Tuning up an aged clock: Circadian clock regulation in metabolism and aging

Sato, S., Solanas, G., Sassone‐Corsi, P., & Benitah, S. A. (2021) · Translational Medicine of Aging · doi:10.1016/j.tma.2021.11.003 · Cited by 21

Glaucoma – ‘A Stiff Eye in a Stiff Body’

Powell, S., Irnaten, M., & O'Brien, C. J. (2022) · Current Eye Research · doi:10.1080/02713683.2022.2039204 · Cited by 20

Machine Learning of Hematopoietic Stem Cell Divisions from Paired Daughter Cell Expression Profiles Reveals Effects of Aging on Self-Renewal

Arai, F., Stumpf, P. S., Ikushima, Y. M., Hosokawa, K., Roch, A., Lutolf, M. P., Suda, T., & MacArthur, B. D. (2020) · Cell Systems · doi:10.1016/j.cels.2020.11.004 · Cited by 19

Non-Coding RNAs Steering the Senescence-Related Progress, Properties, and Application of Mesenchymal Stem Cells

Cai, J., Qi, H., Yao, K., Yao, Y., Jing, D., Liao, W., & Zhao, Z. (2021) · Frontiers in Cell and Developmental Biology · doi:10.3389/fcell.2021.650431 · Cited by 19

Sirt1 m6A modification-evoked Leydig cell senescence promotes Cd-induced testosterone decline

Zheng, X., Zhang, X., Tan, L., Zhang, J., Wang, T., Ling, Q., Wang, H., Ouyang, K.-W., Ouyang, K.-W., Chang, W., et al. (2024) · Ecotoxicology and Environmental Safety · doi:10.1016/j.ecoenv.2024.116884 · Cited by 20

Tissue mosaicism following stem cell aging: blood as an exemplar

Kapadia, C. D., & Goodell, M. A. (2024) · Nature Aging · doi:10.1038/s43587-024-00589-0 · Cited by 18

Muscle stem cell aging: identifying ways to induce tissue rejuvenation

Sousa‐Victor, P., Neves, J., & Muñoz‐Cánoves, P. (2020) · Mechanisms of Ageing and Development · doi:10.1016/j.mad.2020.111246 · Cited by 18

Prolonged hypoxia delays aging and preserves functionality of human amniotic fluid stem cells

Casciaro, F., Borghesan, M., Beretti, F., Zavatti, M., Bertucci, E., Follo, M. Y., Maraldi, T., & Demaria, M. (2020) · Mechanisms of Ageing and Development · doi:10.1016/j.mad.2020.111328 · Cited by 17

Inflammation and hematopoietic stem cells aging

He, H., & Wang, J. (2020) · Blood Science · doi:10.1097/bs9.0000000000000063 · Cited by 16

MYB insufficiency disrupts proteostasis in hematopoietic stem cells, leading to age-related neoplasia

Clarke, M. L., Lemma, R. B., Walton, D. S., Volpe, G., Noyvert, B., Gabrielsen, O. S., & Frampton, J. (2023) · Blood · doi:10.1182/blood.2022019138 · Cited by 20

Entropy Meets Physiology: Should We Translate Aging as Disorder?

Tatullo, M. (2023) · Stem Cells · doi:10.1093/stmcls/sxad084 · Cited by 16

Intestinal microbiota: a new perspective on delaying aging?

Zhang, Y., Wang, X., Li, W., Yang, Y., Wu, Z., Lyu, Y., & Yue, C. (2023) · Frontiers in Microbiology · doi:10.3389/fmicb.2023.1268142 · Cited by 20

Kdm6a-CNN1 axis orchestrates epigenetic control of trauma-induced spinal cord microvascular endothelial cell senescence to balance neuroinflammation for improved neurological repair

Li, C., Qin, T., Zhao, J., Jin, Y., Qin, Y., He, R., Wu, T., Duan, C., Jiang, L., Yuan, F., et al. (2024) · Bone Research · doi:10.1038/s41413-024-00323-x · Cited by 18

Intracellular matrix metalloproteinase-9 mediates epigenetic modifications and autophagy to regulate differentiation in human cardiac stem cells

Yadav, S. K., & Mishra, P. K. (2021) · Stem Cells · doi:10.1002/stem.3330 · Cited by 16

Metabolic regulation in adult and aging skeletal muscle stem cellsPreprint

Sartorelli, V., & Ciuffoli, V. (2024) · Genes & Development · doi:10.1101/gad.352277.124 · Cited by 19

Aging impairs the ability of vascular endothelial stem cells to generate endothelial cells in mice

Shimizu, S., Iba, T., Naito, H., Rahmawati, F. N., Konishi, H., Jia, W., Muramatsu, F., & Takakura, N. (2023) · Angiogenesis · doi:10.1007/s10456-023-09891-8 · Cited by 16

Effects of physical exercise on the prevention of stem cells senescence

Valenti, M. T., Carbonare, L. D., Dorelli, G., & Mottes, M. (2019) · Stem Cell Reviews and Reports · doi:10.1007/s12015-019-09928-w · Cited by 15

Recent advances in understanding the mechanisms determining longevity

Bayersdorf, R., & Schumacher, B. (2019) · F1000Research · doi:10.12688/f1000research.19610.1 · Cited by 14

Stem cell aging

Rudolph, K. L. (2020) · Mechanisms of Ageing and Development · doi:10.1016/j.mad.2020.111394 · Cited by 15

Mitonuclear Communication in Stem Cell Function

Peng, B., Wang, Y., & Zhang, H. (2024) · Cell Proliferation · doi:10.1111/cpr.13796 · Cited by 14

Acetylation profiling by Iseq-Kac reveals insights into HSC aging and lineage decision

Gong, Y., Zhan, H., Wei, N., Liu, M., Liu, Y., Guan, P., Xie, Y., Deng, Y., Pu, Q., Lou, X., et al. (2025) · Nature Chemical Biology · doi:10.1038/s41589-025-01916-1 · Cited by 13

Epigenetic Regulation of Methylation in Determining the Fate of Dental Mesenchymal Stem Cells

Zhang, H., Fu, H. E., Fang, H., Deng, Q., Huang, H., Hou, D., Wang, M., Yao, Q., Si, Q., Chen, R., et al. (2022) · Stem Cells International · doi:10.1155/2022/5015856 · Cited by 13

Applications of Triboelectric Nanogenerators in Bone Tissue Engineering

Wang, N., Dai, Y., Fuh, J. Y. H., Yen, C. C., & Lu, W. F. (2023) · Advanced Materials Technologies · doi:10.1002/admt.202201310 · Cited by 13

Exploring the potential of histone demethylase inhibition in multi-therapeutic approaches for cancer treatment

Li, D., Liang, H., Wei, Y., Xiao, H., Peng, X., & Pan, W. (2023) · European Journal of Medicinal Chemistry · doi:10.1016/j.ejmech.2023.115999 · Cited by 14

Stem cell ageing of the root apical meristem of Arabidopsis thaliana

Wein, A., Gac, A. L., & Laux, T. (2020) · Mechanisms of Ageing and Development · doi:10.1016/j.mad.2020.111313 · Cited by 13

Multiomic identification of senescent stem cell populations critical for osteoarthritis progression and therapy in subchondral bones

Li, P. L., Tang, J., Li, X. T., Zhao, S. R., Xu, R. X., Zhao, Z. D., Zhong, L., Li, Z. L., Yin, B. F., Yu, F., et al. (2025) · Science Advances · doi:10.1126/sciadv.adu2294 · Cited by 16

Kaempferol enhances intestinal repair and inhibits the hyperproliferation of aging intestinal stem cells in Drosophila

Zhao, L., Luo, T., Zhang, H., Fan, X., Zhang, Q., & Chen, H. (2024) · Frontiers in Cell and Developmental Biology · doi:10.3389/fcell.2024.1491740 · Cited by 13

Immune and stem cell compartments of acetabular and femoral bone marrow in hip osteoarthritis patients

Trivanović, D. I., Harder, J., Leucht, M., Kreuzahler, T., Schlierf, B., Holzapfel, B. M., Rudert, M., Jakob, F. J., & Herrmann, M. (2022) · Osteoarthritis and Cartilage · doi:10.1016/j.joca.2022.05.001 · Cited by 12

Isolation and characterization of neural stem/progenitor cells in the subventricular zone of the naked mole-rat brain

Yamamura, Y., Kawamura, Y., Oiwa, Y., Oka, K., Onishi, N., Saya, H., & Miura, K. (2021) · Inflammation and Regeneration · doi:10.1186/s41232-021-00182-7 · Cited by 13

DNA-methylation aging at single-cell level

Rudolph, K. L. (2021) · Nature Aging · doi:10.1038/s43587-021-00154-z · Cited by 12

S -Adenosyl- l -Methionine Alleviates the Senescence of MSCs Through the PI3K/AKT/FOXO3a Signaling Pathway

Shang, L., Li, X., Ding, X., Liu, G., Pan, Z., Chen, X., Wang, Y., Li, B., Wang, T., & Zhao, R. C. (2024) · Stem Cells · doi:10.1093/stmcls/sxae010 · Cited by 12

Organelle dysfunction and its contribution to metabolic impairments in aging and age-related diseases

Heiby, J. C., & Ori‬‬, A. (2022) · Current Opinion in Systems Biology · doi:10.1016/j.coisb.2022.100416 · Cited by 11

Understanding Aging through the Lense of Gut Microbiome

Ira, R., Adwani, J., Krishnan, A. O., Subramanian, G., Yadav, S., Shukla, S., Rao, S., & Prakash, T. (2024) · Exploratory Research and Hypothesis in Medicine · doi:10.14218/erhm.2024.00008 · Cited by 9

Single-cell multi-omics identify novel regulators required for osteoclastogenesis during aging

Li, H., Xu, W., Tan, J.-C., Hong, Y.-M., He, J., Zhao, B.-P., Zhou, J., Zheng, Y.-M., Lei, M., Zheng, X., et al. (2024) · iScience · doi:10.1016/j.isci.2024.110734 · Cited by 12

Short communication: TNF-α and IGF-1 regulates epigenetic mechanisms of HDAC2 and HDAC10

Jiang, W., Block, M. E., & Boosani, C. S. (2022) · PLoS ONE · doi:10.1371/journal.pone.0263190 · Cited by 10

Increasing Complexity of Molecular Landscapes in Human Hematopoietic Stem and Progenitor Cells during Development and Aging

Watt, S. M., Peng, H., & Roberts, I. A. G. (2022) · International Journal of Molecular Sciences · doi:10.3390/ijms23073675 · Cited by 9

Aging of Skeletal Stem Cells

Butler, M., Ambrosi, T. H., Murphy, M. P., & Chan, C. K. F. (2022) · Advances in Geriatric Medicine and Research · doi:10.20900/agmr20220006 · Cited by 12

Dysbiosis and fecal microbiota transplant: Contemplating progress in health, neurodegeneration and longevity

Ahmadi, S., Hasani, A., Khabbaz, A., Poortahmasebi, V., Hosseini, S., Yasdchi, M., Mehdizadehfar, E., Mousavi, Z. B., Hasani, R., Nabizadeh, E., et al. (2024) · Biogerontology · doi:10.1007/s10522-024-10136-4 · Cited by 9

Iron homeostasis and cell clonality drive cancer-associated intestinal DNA methylation drift in aging

Křepelová, A., Rasa, S. M. M., Annunziata, F., Lu, J. N., Giannuzzi, C., Omrani, O., Wyart, E., Porporato, P. E., Ansari, I., Bilenko, D., et al. (2025) · Nature Aging · doi:10.1038/s43587-025-01021-x · Cited by 11

Senescent bone marrow mesenchymal stem cells exacerbate subchondral bone sclerosis and osteoarthritis via the senescence-associated secretory phenotype

Yang, D., Xu, X., Xu, K., Yang, M., Hao, Y., Aihaiti, Y., Li, E., Yan, Y., Lu, C., & Xu, P. (2025) · Stem Cell Research & Therapy · doi:10.1186/s13287-025-04833-1 · Cited by 10

Blockade of TGF-β signalling alleviates human adipose stem cell senescence induced by native ECM in obesity visceral white adipose tissue

Han, X., Li, W., He, X., Lü, X., Zhang, Y. A., Li, Y., Bi, G., Ma, X., Huang, X., Bai, R., et al. (2023) · Stem Cell Research & Therapy · doi:10.1186/s13287-023-03525-y · Cited by 13

The Epigenetic Regulation of Quiescent in Stem Cells

Radak, M., & Fallahi, H. (2023) · Global Medical Genetics · doi:10.1055/s-0043-1777072 · Cited by 10

Inhibition of class I HDACs preserves hair follicle inductivity in postnatal dermal cells

Park, M., Jang, S., Chung, J. H., Kwon, O., & Jo, S. J. (2021) · Scientific Reports · doi:10.1038/s41598-021-03508-0 · Cited by 10

Nutrition and stem cell integrity in aging

Stover, P. J., Field, M. S., Brawley, H. N., Angelin, B., Iversen, P. O., & Frühbeck, G. (2022) · Journal of Internal Medicine · doi:10.1111/joim.13507 · Cited by 9

Regulatory mechanisms of GCN5 in osteogenic differentiation of MSCs in periodontitis

Lu, W., Zhang, L., Ji, K., Ding, L., & Wu, G. (2023) · Clinical and Experimental Dental Research · doi:10.1002/cre2.695 · Cited by 8

A Preview of Selected Articles

Atkinson, S. P. (2017) · Stem Cells · doi:10.1002/stem.2745 · Cited by 9

Immunity, stem cells, and aging

Devaraj, E., Anbalagan, M., Ileng Kumaran, R., & Bhaskaran, N. (2021) · Stem Cells and Aging · doi:10.1016/b978-0-12-820071-1.00006-2 · Cited by 8

Loss of transcriptional heterogeneity in aged human muscle stem cells

Barruet, E., Striedinger, K., Marangoni, P., & Pomerantz, J. H. (2023) · PLoS ONE · doi:10.1371/journal.pone.0285018 · Cited by 8

The Role of Intracellular Potassium in Cell Quiescence, Proliferation, and Death

Marakhova, I. I., Yurinskaya, V. E., & Domnina, A. P. (2024) · International Journal of Molecular Sciences · doi:10.3390/ijms25020884 · Cited by 8

Role of Epigenetics in Chronic Lung Disease

Ritzmann, F., Brand, M., Bals, R., Wegmann, M., & Beißwenger, C. (2025) · Cells · doi:10.3390/cells14040251 · Cited by 8

NUP62 alleviates senescence and promotes the stemness of human dental pulp stem cells via NSD2-dependent epigenetic reprogramming

Wang, X., Wang, L., Zhou, L., Chen, L., Shi, J., Ge, J., Tian, S., Yang, Z., Zhou, Y., Yu, Q., et al. (2025) · International Journal of Oral Science · doi:10.1038/s41368-025-00362-y · Cited by 8

The Vascular Niche for Adult Cardiac Progenitor Cells

Herrero, D., Albericio, G., Higuera, M., Herranz‐López, M., García‐Brenes, M. A., Cordero, A., Roche, E., Sepúlveda, P., Gallardo, C. M., & Bernad, A. (2022) · Antioxidants · doi:10.3390/antiox11050882 · Cited by 10

Monovalent ions and stress-induced senescence in human mesenchymal endometrial stem/stromal cells

Shatrova, A. N., Burova, E., Pugovkina, N. A., Domnina, A. P., Nikolsky, N., & Marakhova, I. I. (2022) · Scientific Reports · doi:10.1038/s41598-022-15490-2 · Cited by 8

Clonal selection parallels between normal and cancer tissues

Salavaty, A., Azadian, E., Naik, S. H., & Currie, P. D. (2023) · Trends in Genetics · doi:10.1016/j.tig.2023.01.007 · Cited by 8

Glutamine-αKG axis affects dentin regeneration and regulates osteo/odontogenic differentiation of mesenchymal adult stem cells via IGF2 m6A modification

Tian, Q., Gao, S., LI, S.-H., Wan, M., Zhou, X., Du, W., Zhou, X., Zheng, L., & Zhou, Y. (2024) · Stem Cell Research & Therapy · doi:10.1186/s13287-024-04092-6 · Cited by 8

Short heat shock has a long-term effect on mesenchymal stem cells’ transcriptome

Ribarski-Chorev, I., Schudy, G., Strauss, C., & Schlesinger, S. (2023) · iScience · doi:10.1016/j.isci.2023.107305 · Cited by 7

Phytochemicals as new therapeutic candidates simultaneously stimulate proliferation and counteract senescence of stem cells

Yuan, T., Xu, X., Zhou, N., Yan, G., Gu, T.-W., & Peng, L. (2022) · Biomedicine & Pharmacotherapy · doi:10.1016/j.biopha.2022.113170 · Cited by 7

Ageing, Metabolic Dysfunction, and the Therapeutic Role of Antioxidants

Santos, A. L., & Sinha, S. (2023) · Sub-cellular biochemistry/Subcellular biochemistry · doi:10.1007/978-3-031-26576-1_15 · Cited by 8

The Rejuvenation and Functional Restoration of Aged Adipose Stem Cells by DUXAP10 Knockdown via the Regulation of the miR-214-3p/RASSF5 Axis

Ren, S., Li, C., Xiong, H., Wu, Q., Wu, X., Xiong, Z., Dong, L., Shu, B., Wei, W., Ma, C., et al. (2024) · Stem Cells Translational Medicine · doi:10.1093/stcltm/szae015 · Cited by 8

Role of stem cells in ageing and age-related diseases

Chaudhary, J. K., Danga, A. K., Kumari, A., Bhardwaj, A., & Rath, P. C. (2025) · Mechanisms of Ageing and Development · doi:10.1016/j.mad.2025.112069 · Cited by 6

Microbial Synthetic Epigenetic Tools Design and Applications

Komera, I., Chen, X., Liu, L., & Gao, C. (2024) · ACS Synthetic Biology · doi:10.1021/acssynbio.4c00125 · Cited by 6

Downregulated SPESP1‐driven fibroblast senescence decreases wound healing in aged mice

Zhong, Y., Zhou, L., Guo, Y., Wang, F., He, F., Cheng, Y., Meng, X., Xie, H., Zhang, Y., & Li, J. (2024) · Clinical and Translational Medicine · doi:10.1002/ctm2.1660 · Cited by 5

Exploring the Mechanisms of Testicular Aging: Advances in Biomarker Research

Chen, W., Zou, H., Xu, H., Cao, R., Zhang, Y., Ma, Y., Wei, L., Zhang, H., & Zhao, J. (2025) · Aging and Disease · doi:10.14336/ad.2025.0070 · Cited by 7

Pathobiology of aging: An introduction to age-related diseases

Caruso, C., Accardi, G., Ligotti, M. E., Vasto, S., & Candore, G. (2021) · Elsevier eBooks · doi:10.1016/b978-0-12-822569-1.00010-x · Cited by 7

Enhancer-priming in ageing human bone marrow mesenchymal stromal cells contributes to immune traitsPreprint

Lai, M. C., Ruiz-Velasco, M., Arnold, C., Sigalova, O. M., Bunina, D., Berest, I., Ding, X., Hennrich, M. L., Poisa-Beiro, L., Claringbould, A., et al. (2021) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.1101/2021.09.03.458728 · Cited by 5

Epigenetic regulation of cis-regulatory elements and transcription factors during development

Khan, S., Mishra, R. K., & Srivastava, S. (2023) · Elsevier eBooks · doi:10.1016/b978-0-12-821785-6.00004-9 · Cited by 5

Endothelial Dysfunction under the Scope of Arterial Hypertension, Coronary Heart Disease, and Diabetes Mellitus using the Angioscan

Marzoog, B. A. (2023) · Cardiovascular & Hematological Agents in Medicinal Chemistry · doi:10.2174/0118715257246589231018053646 · Cited by 5

Intestinal stem cells heterogeneity and clonal dominance during aging: two faces of the same coin?

Širvinskas, D., Annunziata, F., & Neri, F. (2020) · Mechanisms of Ageing and Development · doi:10.1016/j.mad.2020.111247 · Cited by 5

The Bric-à-Brac BTB/POZ transcription factors are necessary in niche cells for germline stem cells establishment and homeostasis through control of BMP/DPP signaling in the Drosophila melanogaster ovary

Saler, L. M., Hauser, V., Bartoletti, M., Mallart, C., Malartre, M., Lebrun, L., Pret, A., Théodore, L., Chalvet, F., & Netter, S. (2020) · PLoS Genetics · doi:10.1371/journal.pgen.1009128 · Cited by 5

mTORC1-Induced Bone Marrow-Derived Mesenchymal Stem Cell Exhaustion Contributes to the Bone Abnormalities in Klotho -Deficient Mice of Premature Aging

Feng, R., Wu, S., Li, R., Huang, K.-L., Zeng, T., Zhou, Z., Zhong, X., Songyang, Z., & Liu, F. (2023) · Stem Cells and Development · doi:10.1089/scd.2022.0243 · Cited by 6

DNA methylation controls hematopoietic stem cell aging

Křepelová, A., & Neri, F. (2023) · Nature Aging · doi:10.1038/s43587-023-00511-0 · Cited by 4

Role of Ionizing Radiation in Shaping the Complex Multi-Layered Epigenome

Rübe, C. E., Al‐razaq, M. A. A., Meier, C., Hecht, M., & Rübe, C. (2025) · Epigenomes · doi:10.3390/epigenomes9030029 · Cited by 5

Low-Input Whole-Genome Bisulfite Sequencing

Křepelová, A., & Neri, F. (2021) · Methods in molecular biology · doi:10.1007/978-1-0716-1597-3_20 · Cited by 4

Epigenetics of hematopoietic stem cell aging

Yokomizo‐Nakano, T., Oshima, M., & Iwama, A. (2024) · Current Opinion in Hematology · doi:10.1097/moh.0000000000000818 · Cited by 4

A Youthful Touch: Reversal of Aging Hallmarks by Cell Reprogramming

Miliotou, E., & de Lázaro, I. (2024) · Cells Tissues Organs · doi:10.1159/000539415 · Cited by 4

Retarding human adipose-derived MSCs senescence and promoting tendon repair using cell sheet engineering with a histone methyltransferase inhibitor

Wang, J., Jian, K., Yang, Q., Gu, C., Sheng, J., Zhou, Y., Yin, H., Zhang, Z., Hua, K., & Zhang, C. (2025) · Scientific Reports · doi:10.1038/s41598-025-89234-3 · Cited by 4

Drosophila ovarian stem cell niche ageing involves coordinated changes in transcription and alternative splicing

Ros, D. E., Romero, J. H., Marín-Menguiano, M., Nusspaumer, G., de Prada, M. B., Irimia, M., Zurita, F., & González‐Reyes, A. (2025) · Nature Communications · doi:10.1038/s41467-025-57901-8 · Cited by 6

Birth month and mortality in Japan: a population-based prospective cohort study

Uji, T., Wada, K., Yamakawa, M., Koda, S., Nakashima, Y., Onuma, S., & Nagata, C. (2021) · Chronobiology International · doi:10.1080/07420528.2021.1903482 · Cited by 4

Uncovering the link between diabetes and cardiovascular diseases: insights from adipose-derived stem cells

Meechem, M. B., Jadli, A. S., & Patel, V. B. (2024) · Canadian Journal of Physiology and Pharmacology · doi:10.1139/cjpp-2023-0282 · Cited by 5

Mouse Aging Cell Atlas Analysis Reveals Global and Cell Type Specific Aging Signatures Revision 1Preprint

Zhang, M. J., Pisco, A. O., Darmanis, S., & Zou, J. (2019) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.1101/2019.12.23.887604 · Cited by 4

Epigenetics in intestinal stem cells: Molecular mechanisms underpinning the guardians of homeostasis in health and aging-related senescence

Liu, B., Wang, Y., Chu, X., Wang, J., Pan, T., Xie, L., Abankwah, J. K., & Bian, Y. (2025) · Pathology - Research and Practice · doi:10.1016/j.prp.2025.156187 · Cited by 3

The Converging Roles of Nucleases and Helicases in Genome Maintenance and the Aging Process

Margariti, A., Daniil, P., & Rampias, T. N. (2025) · Life · doi:10.3390/life15111729 · Cited by 3

Insight into the pathogenesis of interstitial lung diseases and near-to-native lung fibrosis models

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