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Sex-Specific Vasopressin Signaling Buffers Stress-Dependent Synaptic Changes in Female Mice

Loewen, S. P., Baimoukhametova, D. V., & Bains, J. S. (2020) · Journal of Neuroscience · doi:10.1523/jneurosci.1026-20.2020 · Cited by 20 · see citing works

Neural Circuit Mechanisms Involved in Animals’ Detection of and Response to Visual Threats

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Nucleus Accumbens Corticotropin-Releasing Hormone Neurons Projecting to the Bed Nucleus of the Stria Terminalis Promote Wakefulness and Positive Affective State

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Chronic alcohol consumption alters home‐cage behaviors and responses to ethologically relevant predator tasks in mice

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The physiology of stress and the human body’s response to stress

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Regional hypothalamic, amygdala, and midbrain periaqueductal gray matter recruitment during acute pain in awake humans: A 7-Tesla functional magnetic resonance imaging study

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Hypothalamic CRH neurons represent physiological memory of positive and negative experience

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Should I Stay or Should I Go? CRHPVN Neurons Gate State Transitions in Stress-Related Behaviors

Daviu, N., & Bains, J. S. (2021) · Endocrinology · doi:10.1210/endocr/bqab061 · Cited by 18 · see citing works

Neural circuit underlying individual differences in visual escape habituation

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Disruption of tonic endocannabinoid signalling triggers cellular, behavioural and neuroendocrine responses consistent with a stress response

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Preventive Roles of Rice-koji Extracts and Ergothioneine on Anxiety- and Pain-like Responses under Psychophysical Stress Conditions in Male Mice

Piriyaprasath, K., Kakihara, Y., Kurahashi, A., Taiyoji, M., Kodaira, K., Aihara, K., Hasegawa, M., Yamamura, K., & Okamoto, K. (2023) · Nutrients · doi:10.3390/nu15183989 · Cited by 16 · see citing works

Plasticity of intrinsic excitability across the estrous cycle in hypothalamic CRH neurons

Power, E. M., & Iremonger, K. J. (2021) · Scientific Reports · doi:10.1038/s41598-021-96341-4 · Cited by 15 · see citing works

Electroacupuncture alleviates perioperative hypothalamus-pituitary-adrenal axis dysfunction via circRNA-miRNA-mRNA networks

Wang, Y., Hu, W., Han, J., Zheng, J., Jiang, N., Feng, Y., & Tian, Z. (2023) · Frontiers in Molecular Neuroscience · doi:10.3389/fnmol.2023.1115569 · Cited by 15 · see citing works

A parabrachial to hypothalamic pathway mediates defensive behavior

Wang, F., Chen, Y., Lin, Y., Wang, X., Li, K., Han, Y. N., Wu, J., Shi, X., Zhu, Z., Long, C., et al. (2023) · eLife · doi:10.7554/elife.85450 · Cited by 15 · see citing works

Lower Ghrelin Levels Are Associated With Higher Anxiety Symptoms in Adolescents and Young Adults With Avoidant/Restrictive Food Intake Disorder

Sella, A. C., Hadaway, N. A., Stern, C. M., Becker, K. R., Holsen, L. M., Eddy, K. T., Micali, N., Misra, M., Thomas, J. J., & Lawson, E. A. (2023) · The Journal of Clinical Psychiatry · doi:10.4088/jcp.22m14482 · Cited by 15 · see citing works

Role of the Novel Peptide Phoenixin in Stress Response and Possible Interactions with Nesfatin-1

Friedrich, T., & Stengel, A. (2021) · International Journal of Molecular Sciences · doi:10.3390/ijms22179156 · Cited by 15 · see citing works

Efficiency of cell-type specific and generic promoters in transducing oxytocin neurons and monitoring their neural activity during lactation

Rajamani, K. T., Leithead, A. B., Kim, M., Barbier, M., Peruggia, M., Niblo, K., Barteczko, L., Lefèvre, A., Grinevich, V., & Harony‐Nicolas, H. (2021) · Scientific Reports · doi:10.1038/s41598-021-01818-x · Cited by 15 · see citing works

Early-life stress induces persistent astrocyte dysfunction associated with fear generalisationPreprint

Guayasamin, M., Depaauw-Holt, L. R., Adedipe, I. I., Ghenissa, O., Vaugeois, J., Duquenne, M., Rogers, B., Latraverse-Arquilla, J., Peyrard, S., Bosson, A., et al. (2024) · eLife · doi:10.7554/elife.99988 · Cited by 17 · see citing works

Sex differences in androgen receptor, estrogen receptor alpha, and c-Fos co-expression with corticotropin releasing factor expressing neurons in restrained adult mice

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Stressed rats fail to exhibit avoidance reactions to innately aversive social calls

Shukla, A., & Chattarji, S. (2021) · Neuropsychopharmacology · doi:10.1038/s41386-021-01230-z · Cited by 13 · see citing works

Visual-looming Shadow Task with in-vivo Calcium Activity Monitoring to Assess Defensive Behaviors in Mice

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Hypothalamic corticotropin-releasing factor neurons modulate behavior, endocrine, and autonomic stress responses via direct synaptic projections

Rajamanickam, S., & Justice, N. J. (2022) · Current Opinion in Endocrine and Metabolic Research · doi:10.1016/j.coemr.2022.100400 · Cited by 13 · see citing works

Dopamine D2 receptors in WFS1-neurons regulate food-seeking and avoidance behaviors

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A glutamatergic basal forebrain to midbrain circuit mediates wakefulness and defensive behavior

Cai, P., Chen, H., Tang, W.-T., Hu, Y., Chen, S.-Y., Lu, J., Lin, Z., Huang, S., Hu, L., Su, W.-K., et al. (2022) · Neuropharmacology · doi:10.1016/j.neuropharm.2022.108979 · Cited by 12 · see citing works

Brain-wide perception of the emotional valence of light is regulated by distinct hypothalamic neurons

Wagle, M. D., Zarei, M., Lovett-Barron, M., Poston, K. T., Xu, J., Ramey, V., Pollard, K. S., Prober, D. A., Schulkin, J. A., Deisseroth, K. A., et al. (2022) · Molecular Psychiatry · doi:10.1038/s41380-022-01567-x · Cited by 13 · see citing works

The “Primitive Brain Dysfunction” Theory of Autism: The Superior Colliculus Role

Jure, R. (2022) · Frontiers in Integrative Neuroscience · doi:10.3389/fnint.2022.797391 · Cited by 13 · see citing works

Hyperexcitation of the glutamatergic neurons in lateral hypothalamus induced by chronic pain contributes to depression-like behavior and learning and memory impairment in male mice

Meng, L., Zheng, X., Xie, K., Li, Y., Liu, D., Xu, Y., Zhang, J., Wu, F., & Guo, G. (2024) · Neurobiology of Stress · doi:10.1016/j.ynstr.2024.100654 · Cited by 11 · see citing works

Volumetric changes in hypothalamic subunits in patients with relapsing remitting multiple sclerosis

Genç, B., Şen, S., Aslan, K., & İncesu, L. (2023) · Neuroradiology · doi:10.1007/s00234-023-03122-z · Cited by 11 · see citing works

The Hypothalamic Epigenetic Landscape in Dietary Obesity

Ma, K., Yin, K., Li, J., Ma, L., Zhou, Q. Y., Lu, X., Li, B., Li, J., Wei, G., & Zhang, G. (2023) · Advanced Science · doi:10.1002/advs.202306379 · Cited by 11 · see citing works

Development and experience-dependent modulation of the defensive behaviors of mice to visual threats

Narushima, M., Agetsuma, M., & Nabekura, J. (2022) · The Journal of Physiological Sciences · doi:10.1186/s12576-022-00831-7 · Cited by 10 · see citing works

Male subfertility effects of sub-chronic ethanol exposure during stress in a rat model

Fozooni, R., Shirazi, M. R. J., Saedi, S., Jahromi, B. N., Khoradmehr, A., Anvari, M., Rahmanifar, F., Khodabandeh, Z., & Tamadon, A. (2021) · Alcohol · doi:10.1016/j.alcohol.2021.08.003 · Cited by 10 · see citing works

Hypothalamic Microglia as Dual Hubs Orchestrating Local and Systemic Homeostasis in the Periphery–Central–Periphery Axis

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Psilocybin induces sex- and context-specific recruitment of the stress axis

Cook, S. G., Lee, S., Ference, E., Shi, Y., Baimoukhametova, D. V., Rojas‐Carvajal, M., Hen, R., Bains, J. S., Turi, G. F., & Füzesi, T. (2025) · Current Biology · doi:10.1016/j.cub.2025.11.031 · Cited by 9 · see citing works

Effects of chronic exposure to bisphenol A in adult female mice on social behavior, vasopressin system, and estrogen membrane receptor (GPER1)

Bonaldo, B., Casile, A., Bettarelli, M., Gotti, S., Panzica, G., & Marraudino, M. (2021) · European Journal of Histochemistry · doi:10.4081/ejh.2021.3272 · Cited by 9 · see citing works

State-dependent activity dynamics of hypothalamic stress effector neurons

Ichiyama, A., Mestern, S., Benigno, G., Scott, K. E., Allman, B. L., Muller, L., & Inoue, W. (2022) · eLife · doi:10.7554/elife.76832 · Cited by 9 · see citing works

Impact and Role of Hypothalamic Corticotropin Releasing Hormone Neurons in Withdrawal from Chronic Alcohol Consumption in Female and Male Mice

Neira, S., Lee, S., Hassanein, L. A., Sides, T. R., D’Ambrosio, S., Boyt, K. M., Bains, J. S., & Kash, T. L. (2023) · Journal of Neuroscience · doi:10.1523/jneurosci.1153-23.2023 · Cited by 9 · see citing works

30th Annual Computational Neuroscience Meeting: CNS*2021–Meeting Abstracts

Arora, K., Zulfiqar, I., Schultheiss, H., Martino, F. D., Gulban, O. F., Lage‐Castellanos, A., & Moerel, M. (2021) · Journal of Computational Neuroscience · doi:10.1007/s10827-021-00801-9 · Cited by 9 · see citing works

Turning strains into strengths for understanding psychiatric disorders

Moore, S. J., Murphy, G. G., & Cazares, V. A. (2020) · Molecular Psychiatry · doi:10.1038/s41380-020-0772-y · Cited by 9 · see citing works

The activation of catecholamine neurons in the rostral ventrolateral medulla drives ventricular remodeling after myocardial ischemia/reperfusion injury

Xu, S., Zhang, R., Jin, S., Luo, H., Hou, Y., He, S., Zhou, S., Zhao, R., Chen, Z., Wang, B., et al. (2025) · Basic Research in Cardiology · doi:10.1007/s00395-025-01128-7 · Cited by 8 · see citing works

Beyond the HPA axis: Synaptic circuits of PVNCRH neurons in stress-related psychiatric disorders

Zheng, J., Yue, N., Tian, Z., Yu, J., & Li, B. (2026) · Pharmacological Research · doi:10.1016/j.phrs.2026.108179 · Cited by 8 · see citing works

Neonatal di-(2-ethylhexyl)phthalate exposure induces permanent alterations in secretory CRH neuron characteristics in the hypothalamus paraventricular region of adult male rats

Li, L., Su, Y., Wang, S., Wang, C., Ruan, N., Hu, Z., Cheng, X., Chen, J., Yuan, K., Li, P., et al. (2023) · Experimental Neurology · doi:10.1016/j.expneurol.2023.114616 · Cited by 8 · see citing works

Blast-Induced Mild Traumatic Brain Injury Alterations of Corticotropin-Releasing Factor Neuronal Activity in the Mouse Hypothalamic Paraventricular Nucleus

Simmons, S. C., Langlois, L. D., Oyola, M. G., Gouty, S., Wu, T. J., & Nugent, F. S. (2022) · Frontiers in Synaptic Neuroscience · doi:10.3389/fnsyn.2021.804898 · Cited by 8 · see citing works

Sex-specific hypothalamic neural projection activity drives caregiving in mice

Carta, I., Arora, T., Lutzu, S., Podda, G., Ortega, G. N. V., Rudolph, S., & Autry, A. E. (2025) · Nature Communications · doi:10.1038/s41467-025-59352-7 · Cited by 7 · see citing works

Transcutaneous auricular vagus nerve stimulation inhibits food intake and body weight gain through the orexin dependent pathway in high fat diet mice

Zhang, Y., Song, D., Liu, R., Gong, H., Wang, C., Zhao, M., & Zhang, K. (2025) · Scientific Reports · doi:10.1038/s41598-025-01964-6 · Cited by 7 · see citing works

Fronto-insular circuit mechanisms of accelerated intermittent theta burst stimulation

Johnson, S. B., Rocks, D., Chalençon, L., Johnson, K., Hassan, U., Arefin, A., Akgül, G., Donatelle, A., Asher, H., Elbau, I., et al. (2026) · Cell · doi:10.1016/j.cell.2026.04.030 · Cited by 8 · see citing works

Distinguishing motion artifacts during optical fiber-based in-vivo hemodynamics recordings from brain regions of freely moving rodents

Bisht, A., Simone, K., Bains, J. S., & Murari, K. (2024) · Neurophotonics · doi:10.1117/1.nph.11.s1.s11511 · Cited by 7 · see citing works

Early-life stress induces persistent astrocyte dysfunction associated with fear generalisation

Guayasamin, M., Depaauw-Holt, L. R., Adedipe, I. I., Ghenissa, O., Vaugeois, J., Duquenne, M., Rogers, B., Latraverse-Arquilla, J., Peyrard, S., Bosson, A., et al. (2025) · eLife · doi:10.7554/elife.99988.3 · Cited by 7 · see citing works

Encoding the glucose identity by discrete hypothalamic neurons via the gut-brain axis

Kim, J., Kim, S., Jung, W., Kim, Y., Lee, S., Kim, S. H., Park, H.-Y., Yoo, D. Y., Hwang, I. K., Froemke, R. C., et al. (2025) · Neuron · doi:10.1016/j.neuron.2025.05.024 · Cited by 7 · see citing works

Role of the paraventricular nucleus of the hypothalamus in sleep–wake regulation

Jiang, S., Chen, L., Huang, Z., & Chen, C. (2022) · Brain Science Advances · doi:10.26599/bsa.2022.9050017 · Cited by 7 · see citing works

Sex differences in α‐adrenergic receptor function contribute to impaired hypothalamic metaplasticity following chronic intermittent ethanol exposure

Munier, J. J., Marty, V. N., & Spigelman, I. (2022) · Alcoholism Clinical and Experimental Research · doi:10.1111/acer.14900 · Cited by 7 · see citing works

Differential activation of lateral parabrachial nuclei and their limbic projections during head compared with body pain: A 7-Tesla functional magnetic resonance imaging study

Robertson, R. V., Meylakh, N., Crawford, L. S., Mendoza, F. A. T., Macey, P. M., Macefield, V. G., Keay, K. A., & Henderson, L. A. (2024) · NeuroImage · doi:10.1016/j.neuroimage.2024.120832 · Cited by 7 · see citing works

Relaxin family peptide receptor 3 ( RXFP3 ) expressing cells in the zona incerta/lateral hypothalamus augment behavioural arousal

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Highly Efficient Classification of Time‐Series Based on Resistive Switching Cluster‐Assembled Materials

Profumo, F., Borghi, F., Angì, T., Maschietto, M., Vassanelli, S., & Milani, P. (2025) · Advanced Intelligent Systems · doi:10.1002/aisy.202401150 · Cited by 6 · see citing works

Hypothalamic CRH neurons: A crossroad between stress and metabolism

Jiang, Z., & Tong, Q. (2022) · Current Opinion in Endocrine and Metabolic Research · doi:10.1016/j.coemr.2022.100384 · Cited by 6 · see citing works

Estradiol regulates voltage-gated potassium currents in corticotropin-releasing hormone neurons

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Paraventricular Mast Cell-Derived Histamine Activates CRH Neurons to Mediate Adult Visceral Hypersensitivity Induced by Neonatal Maternal Separation

Chen, Z., Zhou, T., Li, Y., Li, T., Ding, Z., & Liu, L. (2023) · Brain Sciences · doi:10.3390/brainsci13111595 · Cited by 5 · see citing works

Windows into stress: a glimpse at emerging roles for CRH ^PVN neurons

Rasiah, N. P., Loewen, S. P., & Bains, J. S. (2023) · Physiological Reviews · doi:10.1152/physrev.00056.2021 · Cited by 62 · see citing works

Should I Stay or Should I Go? CRHPVN Neurons Gate State Transitions in Stress-Related Behaviors

Daviu, N., & Bains, J. S. (2021) · Endocrinology · doi:10.1210/endocr/bqab061 · Cited by 18 · see citing works

Representations of CRH PVN neurons and their dynamics

Simone, K. (2022) · Libraries and Cultural Resources (University of Calgary) · doi:10.11575/prism/dspace/41350

Hypothalamic CRH neurons orchestrate complex behaviours after stress

Füzesi, T., Daviu, N., Wamsteeker Cusulin, J. I., Bonin, R. P., & Bains, J. S. (2016) · Nature Communications · doi:10.1038/ncomms11937 · Cited by 316 · see citing works

The e¡ect of stressor controllability on stress-induced neuropeptide mRNA expression within the paraventricular nucleus of the hypothalamus

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