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A toolbox for the longitudinal assessment of healthspan in aging mice

Bellantuono, I., de Cabo, R., Ehninger, D., Di Germanio, C., Lawrie, A., Miller, J., Mitchell, S. J., Navas-Enamorado, I., Potter, P. K., Tchkonia, T., Trejo, J. L., Lamming, D. W.·2020·Nature Protocols
DOI 10.1038/s41596-019-0256-1PMC PMC7002283
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  • TAC-treated aged mice showed improved rotarod performance and grip strength.

    “In addition, TAC-treated aged mice showed improved rotarod performance and grip strength (Figures S5H and S5I, respectively), which are known to decline with advancing age,40 consistent with improved motor coordination and muscle strength.”

    From TERT activation targets DNA methylation and multiple aging hallmarks (2024) · cites this paper as [40]

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Metadata

Authors
Bellantuono, I., de Cabo, R., Ehninger, D., Di Germanio, C., Lawrie, A., Miller, J., Mitchell, S. J., Navas-Enamorado, I., Potter, P. K., Tchkonia, T., Trejo, J. L., & Lamming, D. W.
ORCID
Venue
Nature Protocols
Publisher
Springer Science and Business Media LLC
Published
2020-01-08
Volume
15
Issue
2
Pages
540-574
ISSN
  • 1754-2189
  • 1750-2799
DOI
10.1038/s41596-019-0256-1
PMC
PMC7002283
Cited by
145
References
28
Language
en
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