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Profound Impairment in Social Recognition and Reduction in Anxiety-Like Behavior in Vasopressin V1a Receptor Knockout Mice
Abstract
Considerable evidence suggests that arginine vasopressin (AVP) is critically involved in the regulation of many social and nonsocial behaviors, including emotionality. The existence of two AVP receptors in the brain, namely the V1a and V1b subtypes, and the lack of clear pharmacological data using selective agonists or antagonists, make it difficult to determine which receptor is responsible for the AVP-mediated effects on behavior. Here we report the behavioral effects of a null mutation in the V1a receptor (V1aR) in male mice. Male mice lacking functional V1aR (V1aRKO) exhibit markedly reduced anxiety-like behavior and a profound impairment in social recognition. V1aRKO performed normally on spatial and nonsocial olfactory learning and memory tasks. Acute central administration of AVP robustly stimulated stereotypical scratching and autogrooming in wild-type (WT), but not V1aRKO males. AVP and oxytocin (OT) mRNA and OT receptor-binding levels were similar in WT and V1aRKO mice. Given the current findings, the V1aR may provide a novel potential pharmacological target for social and affective disorders including autism, and anxiety disorders.
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“The OT and AVP systems are also involved in more subtle aspects of social cognition, including recognising individuals as familiar (8,9).”
From Comparative Perspectives on Oxytocin and Vasopressin Receptor Research in Rodents and Primates: Translational Implications (2016) · cites this paper as [9]
In the citing paper
“V1aR and V1bR are both expressed in the brain and are the most well-known mediators of the effects of VP in the brain on social behavior.”
From Vasopressin and oxytocin receptor systems in the brain: Sex differences and sex-specific regulation of social behavior (2016) · cites this paper as Bielsky et al., 2004
In the citing paper
“V1aR has been implicated in pair bonding, maternal care, aggression, social recognition, and social play”
From Vasopressin and oxytocin receptor systems in the brain: Sex differences and sex-specific regulation of social behavior (2016) · cites this paper as Bielsky et al., 2004
In the citing paper
“Finally, oxytocin can also bind to AVPR1A receptors25, which have also been linked to social functioning26.”
From Oxytocin pathway gene networks in the human brain (2019) · cites this paper as [26]
Citations
Cites
Developments of a water-maze procedure for studying spatial learning in the rat
Morris, R. (1984) · Journal of Neuroscience Methods · doi:10.1016/0165-0270(84)90007-4 · Cited by 7,180
Behavioural despair in rats: A new model sensitive to antidepressant treatments
Porsolt, R. D., Anton, G., Blavet, N., & Jalfre, M. (1978) · European Journal of Pharmacology · doi:10.1016/0014-2999(78)90118-8 · Cited by 3,138
Social amnesia in mice lacking the oxytocin gene
Ferguson, J. N., Young, L. J., Hearn, E. F., Matzuk, M. M., Insel, T. R., & Winslow, J. T. (2000) · Nature Genetics · doi:10.1038/77040 · Cited by 1,130
Self-citationOxytocin in the Medial Amygdala is Essential for Social Recognition in the Mouse
Ferguson, J. N., Aldag, J. M., Insel, T. R., & Young, L. J. (2001) · The Journal of Neuroscience · doi:10.1523/jneurosci.21-20-08278.2001 · Cited by 1,043
Self-citationA role for central vasopressin in pair bonding in monogamous prairie voles
Winslow, J. T., Hastings, N., Carter, C. S., Harbaugh, C. R., & Insel, T. R. (1993) · Nature · doi:10.1038/365545a0 · Cited by 948 · cited 1×
“…paternal behavior, social recognition, aggression, and affiliation, as well as anxiety-like behavior (Ferris et al, 1984, 1986; Le Moal et al, 1987; Winslow et al, 1993; Landgraf et al, 1995; Bamshad and Albers 1996; Liebsch et al, 1996; Everts and Koolhaas, 1997; Young et al, 1999; Parker and…”
BackgroundOxytocin is required for nursing but is not essential for parturition or reproductive behavior.
Nishimori, K., Young, L. J., Guo, Q., Wang, Z., Insel, T. R., & Matzuk, M. M. (1996) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.93.21.11699 · Cited by 734
Self-citationVasopressinergic control of pituitary adrenocorticotropin secretion comes of age
Antoni, F. A. (1993) · Frontiers in Neuroendocrinology · doi:10.1006/frne.1993.1004 · Cited by 636
The neuroendocrine basis of social recognition
Ferguson, J. N., Young, L. J., & Insel, T. R. (2002) · Frontiers in Neuroendocrinology · doi:10.1006/frne.2002.0229 · Cited by 494
Self-citationYoung, L. J., Nilsen, R., Waymire, K. G., MacGregor, G. R., & Insel, T. R. (1999) · Nature · doi:10.1038/23475 · Cited by 488
Self-citationGriebel, G., Simiand, J., Serradeil-Le Gal, C., Wagnon, J., Pascal, M., Scatton, B., Maffrand, J.-P., & Soubrié, P. (2002) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.092012099 · Cited by 471
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Zhou, Z., Yang, X., Yuan, B.-L., Niu, L., Zhou, X. P., Huang, W., Feng, X., & Zhou, L. (2014) · Journal of Molecular Neuroscience · doi:10.1007/s12031-014-0468-3 · Cited by 20
Varga, J. M., Domokos, Á., Barna, I., Jankord, R., Bagdy, G., & Zelena, D. (2010) · Brain Research Bulletin · doi:10.1016/j.brainresbull.2010.09.014 · Cited by 20
Fakhoury, M. (2017) · Progress in Neuro-Psychopharmacology and Biological Psychiatry · doi:10.1016/j.pnpbp.2017.02.026 · Cited by 21
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Freeman, S. M., & Young, L. J. (2013) · Cambridge University Press eBooks · doi:10.1017/cbo9781139017855.011 · Cited by 19
Self-citationGene Regulation System of Vasopressin and Corticotoropin-Releasing Hormone
Yoshida, M. (2008) · Gene Regulation and Systems Biology · doi:10.4137/grsb.s424 · Cited by 20
Oxytocin and vasopressin in the hippocampus
Zăgrean, A., Georgescu, I.-A., Ieșanu, M. I., Ionescu, R.-B., Haret, R. M., Panaitescu, A. M., & Zăgrean, L. (2022) · Vitamins and hormones · doi:10.1016/bs.vh.2021.11.002 · Cited by 20
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Paletta, P., Bass, N., Aspesi, D., & Choleris, E. (2022) · Current topics in behavioral neurosciences · doi:10.1007/7854_2022_325 · Cited by 23
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Okdeh, N., Mahfouz, G., Harb, J., Sabatier, J., Roufayel, R., Gazo-Hanna, E., Kovacic, H., & Fajloun, Z. (2023) · Bioengineering · doi:10.3390/bioengineering10020258 · Cited by 19
Varga, J. M., Klausz, B., Domokos, Á., Kálmán, S., Pákáski, M., Szücs, S., Garab, D., Zvara, Á., Puskás, L. G., Kalman, J. L., et al. (2013) · Brain Research Bulletin · doi:10.1016/j.brainresbull.2013.10.010 · Cited by 19
Syed, N., Martens, C. A., & Hsu, W. H. (2007) · Journal of Neurochemistry · doi:10.1111/j.1471-4159.2007.04737.x · Cited by 19
Hernández‐Pérez, O. R., Crespo‐Ramírez, M., Ferrer, Y. C., Anı́as-Calderón, J., Zhang, L., Roldán-Roldán, G., Aguilar‐Roblero, R. A., Borroto‐Escuela, D. O., Fuxé, K., & de la Mora, M. P. (2018) · Psychopharmacology · doi:10.1007/s00213-017-4817-0 · Cited by 19
Olfactory Assays for Mouse Models of Neurodegenerative Disease
Lehmkuhl, A. M., Dirr, E. R., & Fleming, S. M. (2014) · Journal of Visualized Experiments · doi:10.3791/51804-v · Cited by 19
Nishiwaki-Yasuda, K., SUZUKI, A., Kakita, A., Sekiguchi, S., Asano, S., NISHII, K., Nagao, S., Oiso, Y., & Itoh, M. (2007) · Endocrine Journal · doi:10.1507/endocrj.k06-093 · Cited by 19
Dominant–subordinate relationships in hamsters: Sex differences in reactions to familiar opponents
Bath, K. G., & Johnston, R. E. (2006) · Hormones and Behavior · doi:10.1016/j.yhbeh.2006.10.009 · Cited by 19
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Hu, H., Zarate, C. A., & Verbalis, J. G. (2024) · Psychiatry and Clinical Neurosciences · doi:10.1111/pcn.13703 · Cited by 18
Reed, M. D., Price, K. E., Archbold, J., Moffa, A., & Febo, M. (2012) · Brain Research · doi:10.1016/j.brainres.2012.11.045 · Cited by 18
Vasopressin eliminates the expression of familiar odor bias in neonatal female mice through V1aR
Hammock, E. A. D., Law, C. S., & Levitt, P. R. (2012) · Hormones and Behavior · doi:10.1016/j.yhbeh.2012.12.006 · Cited by 20
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Parker, K. J. (2022) · Molecular Psychiatry · doi:10.1038/s41380-022-01532-8 · Cited by 19
Lim, C. E., Turner, L. H., & Heinrichs, S. C. (2006) · Seizure · doi:10.1016/j.seizure.2006.10.006 · Cited by 18
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Broniarczyk-Czarniak, M., Szemraj, J., Śmigielski, J., & Gałecki, P. (2022) · Current Issues in Molecular Biology · doi:10.3390/cimb44010025 · Cited by 16
Oztan, O., Zyga, O., Stafford, D. E. J., & Parker, K. J. (2022) · Neuroscience & Biobehavioral Reviews · doi:10.1016/j.neubiorev.2022.104870 · Cited by 18
Yuan, W., Li, L., Hou, W., He, Z., Wang, L., Zhang, J., Yang, Y., Cai, W., Guo, Q., Zhang, X., et al. (2019) · Neuroendocrinology · doi:10.1159/000501798 · Cited by 17
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Brydges, N. M., Hall, J., Best, C., Rule, L., Watkin, H., Drake, A. J., Lewis, C., Thomas, K. L., & Hall, J. (2019) · Translational Psychiatry · doi:10.1038/s41398-019-0678-0 · Cited by 18
Borderline personality disorder: current drug treatments and future prospects
Olabi, B., & Hall, J. (2010) · Therapeutic Advances in Chronic Disease · doi:10.1177/2040622310368455 · Cited by 19
The Role of the Oxytocin/Arginine Vasopressin System in Animal Models of Autism Spectrum Disorder
Zhang, R., Xu, X., Zhang, H.-F., Han, S., & Han, J. (2017) · Advances in anatomy, embryology and cell biology · doi:10.1007/978-3-319-52498-6_8 · Cited by 17
Pro-BDNF Knockout Causes Abnormal Motor Behaviours and Early Death in Mice
Li, H., Lin, L.-Y., Zhang, Y., Lim, Y., Rahman, M., Beck, A., Al-Hawwas, M., Feng, S., Bobrovskaya, L., & Zhou, X.-F. (2020) · Neuroscience · doi:10.1016/j.neuroscience.2020.05.007 · Cited by 16
Saavedra, J. M., & Pavel, J. (2005) · Drug Development Research · doi:10.1002/ddr.20027 · Cited by 16
Music genetics research: Association with musicality of a polymorphism in the AVPR1A gene
Mariath, L. M., da Silva, A. M., Kowalski, T. W., Gattino, G., de Araújo, G. A., Figueiredo, F. G., Tagliani‐Ribeiro, A., Roman, T., Vianna, F. S. L., Schüler‐Faccini, L., et al. (2017) · Genetics and Molecular Biology · doi:10.1590/1678-4685-gmb-2016-0021 · Cited by 17
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García-Domínguez, I., Suárez‐Pereira, I., Santiago, M., Pérez-Villegas, E. M., Bravo, L., López‐Martín, C., Roca-Ceballos, M. A., García‐Revilla, J., Espinosa‐Oliva, A. M., Rodríguez‐Gómez, J. A., et al. (2020) · Progress in Neuro-Psychopharmacology and Biological Psychiatry · doi:10.1016/j.pnpbp.2020.110030 · Cited by 16
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Francesconi, W., Olivera-Pasilio, V., Berton, F., Olson, S. L., Chudoba, R., Monroy, L. M., Krabichler, Q., Grinevich, V., & Dabrowska, J. (2025) · Cell Reports · doi:10.1016/j.celrep.2025.115768 · Cited by 14
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Aulino, E. A., & Caldwell, H. K. (2020) · Journal of Neuroendocrinology · doi:10.1111/jne.12835 · Cited by 15
Paudel, P., Shrestha, S., Park, S. E., Seong, S. H., Fauzi, F. M., Jung, H. A., & Choi, J. S. (2020) · ACS Omega · doi:10.1021/acsomega.0c03649 · Cited by 13
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Benjamin, C. (2012) · InTech eBooks · doi:10.5772/50422 · Cited by 14
Masuki, S., Sumiyoshi, E., Koshimizu, T., Qian, J., Higuchi, K., Tsujimoto, G., & Nosé, H. (2013) · The Journal of Physiology · doi:10.1113/jphysiol.2013.251876 · Cited by 15
Wood, R. I., Knoll, A. T., & Levitt, P. R. (2015) · Physiology & Behavior · doi:10.1016/j.physbeh.2015.08.018 · Cited by 13
Clarke, L., Zyga, O., Pineo-Cavanaugh, P. L., Jeng, M., Fischbein, N. J., Partap, S., Katznelson, L. J., & Parker, K. J. (2022) · Neuroscience & Biobehavioral Reviews · doi:10.1016/j.neubiorev.2022.104770 · Cited by 13
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László, K., Vörös, D., Correia, P., Fazekas, C. L., Török, B., Plangár, I., & Zelena, D. (2023) · Biomedicines · doi:10.3390/biomedicines11102603 · Cited by 13
Kim, T.-Y., Roychaudhury, A., Kim, H.-T., Choi, T., Baek, S. T., Thyme, S. B., & Kim, C. (2024) · Translational Psychiatry · doi:10.1038/s41398-024-02806-1 · Cited by 13
Garcia, A. N., Depena, C., Yin, W., & Gore, A. C. (2015) · Molecular and Cellular Endocrinology · doi:10.1016/j.mce.2015.10.004 · Cited by 13
Olexová, L., Talarovičová, A., Lewis-Evans, B., Borbélyová, V., & Kršková, L. (2012) · Neuroscience Research · doi:10.1016/j.neures.2012.10.004 · Cited by 13
HP1BP3 expression determines maternal behavior and offspring survival
Garfinkel, B. P., Arad, S., Neuner, S. M., Netser, S., Wagner, S., Kaczorowski, C. C., Rosen, C. J., Gal, M., Soreq, H., & Orly, J. (2016) · Genes Brain & Behavior · doi:10.1111/gbb.12312 · Cited by 13
Boyle, C. A., Hu, B., Quaintance, K. L., & Lei, S. (2021) · The Journal of Physiology · doi:10.1113/jp281260 · Cited by 12
Jorgensen, W. T., Gulliver, D. W., Werry, E. L., Reekie, T. A., Connor, M. A., & Kassiou, M. (2015) · European Journal of Medicinal Chemistry · doi:10.1016/j.ejmech.2015.11.050 · Cited by 13
Murta, V., Seiffe, A., & Depino, A. M. (2023) · Sexes · doi:10.3390/sexes4030024 · Cited by 13
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Balthazart, J., & Young, L. J. (2014) · Elsevier eBooks · doi:10.1016/b978-0-12-397175-3.00048-x · Cited by 12
Self-citationCudnoch‐Jędrzejewska, A., Puchalska, L., Szczepanska‐Sadowska, E. K., Wsół, A., Kowalewski, S., & Czarzasta, K. (2014) · Physiology & Behavior · doi:10.1016/j.physbeh.2014.06.011 · Cited by 12
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Menzies, J. R. W., Skibicka, K. P., Dickson, S. L., & Leng, G. (2012) · Obesity Facts · doi:10.1159/000338237 · Cited by 12
Nugent, B. M., Stiver, K. A., Hofmann, H. A., & Alonzo, S. H. (2018) · Molecular Ecology · doi:10.1111/mec.14999 · Cited by 12
Oztan, O., Talbot, C. F., Argilli, E., Maness, A. C., Simmons, S. M. V., Mohsin, N., Rosso, L. A. D., Garner, J. P., Sherr, E. H., Capitanio, J. P., et al. (2021) · Molecular Autism · doi:10.1186/s13229-021-00442-w · Cited by 12
Quintana, D. S. (2018) · OSF Preprints (OSF Preprints) · Cited by 12
Csabafi, K., Ibos, K. E., Bodnár, É., Filkor, K., Szakács, J., & Bagosi, Z. (2023) · Biomedicines · doi:10.3390/biomedicines11092446 · Cited by 14
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Satao, K. S., & Doshi, G. (2024) · Pharmacology Biochemistry and Behavior · doi:10.1016/j.pbb.2024.173878 · Cited by 12
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Donaldson, Z. R., & Young, L. J. (2016) · Springer eBooks · doi:10.1007/978-1-4939-3777-6_4 · Cited by 12
Self-citationDevelopment of social recognition ability in female rats: Effect of pubertal ovarian hormones
Yoest, K. E., Henry, M. G., Velisek, H. A., & Veenema, A. H. (2023) · Hormones and Behavior · doi:10.1016/j.yhbeh.2023.105347 · Cited by 13
Abnormal Social Behavior in Nicotinic Acetylcholine Receptor 4 Subunit-Null Mice
Salas, R., Fung, B., Sturm, R. M., & Biasi, M. D. (2012) · Nicotine & Tobacco Research · doi:10.1093/ntr/nts215 · Cited by 11
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Ricceri, L., Michetti, C., & Scattoni, M. L. (2016) · Elsevier eBooks · doi:10.1016/b978-0-12-800109-7.00017-0 · Cited by 13
Peptide-Liganded G Protein-Coupled Receptors as Neurotherapeutics
Eiden, L. E., Goosens, K. A., Jacobson, K. A., Leggio, L., & Zhang, L. (2020) · ACS Pharmacology & Translational Science · doi:10.1021/acsptsci.0c00017 · Cited by 11
Hu, B., Boyle, C. A., & Lei, S. (2021) · Journal of Cellular Physiology · doi:10.1002/jcp.30535 · Cited by 10
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Yayou, K., Seo, T., Uetake, K., Ito, S., & Nakamura, M. (2006) · Physiology & Behavior · doi:10.1016/j.physbeh.2006.09.030 · Cited by 11
Grigorenko, E. L. (2011) · Wiley eBooks · doi:10.1002/9781118092699.ch3 · Cited by 11
Quintana, D. S., Rokicki, J., van der Meer, D., Alnæs, D., Kaufmann, T., Córdova‐Palomera, A., Dieset, I., Andreassen, O. A., & Westlye, L. T. (2017) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.1101/149526 · Cited by 12
Persico, A. M., Asta, L., Chehbani, F., Mirabelli, S., Parlatini, V., Cortese, S., Arango, C., & Vitiello, B. (2024) · Progress in Neuro-Psychopharmacology and Biological Psychiatry · doi:10.1016/j.pnpbp.2024.111176 · Cited by 11
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Oyama, T., Momohara, Y., Yano, H., Kamio, M., Fujiyama, N., & Nagayama, T. (2020) · Behaviour · doi:10.1163/1568539x-bja10014 · Cited by 10
BAXTER, A. B., Karaskiewicz, C. L., Campbell, L. A., Kinnally, E. L., Ferrer, E. E., Seelke, A. M. H., Freeman, S. M., & Bales, K. L. (2023) · Journal of Neuroendocrinology · doi:10.1111/jne.13304 · Cited by 10
Moritoh, S., Sato-Numata, K., Okada, Y., & Koizumi, A. (2011) · PubMed Central · Cited by 10
Freeman, A. R., Hare, J. F., & Caldwell, H. K. (2019) · Journal of Neuroscience Research · doi:10.1002/jnr.24400 · Cited by 10
Paudel, P., Kim, D. H., Jeon, J., Park, S. E., Seong, S. H., Jung, H. A., & Choi, J. S. (2021) · International Journal of Molecular Sciences · doi:10.3390/ijms22073335 · Cited by 10
Prajapati, R., Seong, S. H., Paudel, P., Park, S. E., Jung, H. A., & Choi, J. S. (2021) · ACS Omega · doi:10.1021/acsomega.1c04109 · Cited by 10
Wu, R., Jiang, X., Wu, X., Pang, J., Tang, Y., Ren, Z., Yang, F., Yang, S., & Wei, W. (2022) · Behavioural Processes · doi:10.1016/j.beproc.2022.104624 · Cited by 10
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Sigling, H. O., Wolterink‐Donselaar, I. G., & Spruijt, B. M. (2009) · European Journal of Pharmacology · doi:10.1016/j.ejphar.2009.03.070 · Cited by 10
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Fleming, S. M., & Chesselet, M. (2009) · Advances in behavioral biology · doi:10.1007/978-1-4419-0340-2_37 · Cited by 10
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Kenyon, A. R., Alvares, G. A., Hickie, I. B., & Guastella, A. J. (2013) · Journal of Hormones · doi:10.1155/2013/386306 · Cited by 10
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Shimizu, K., Nakamura, K., Yokosuka, M., & Kondo, Y. (2018) · Physiology & Behavior · doi:10.1016/j.physbeh.2018.09.016 · Cited by 10
Chapter 4.1 Peptide receptor ligands to treat anxiety disorders
Steckler, T. (2008) · Handbook of behavioral neuroscience · doi:10.1016/s1569-7339(07)00010-0 · Cited by 10
Hormonal and Pheromonal Modulation of the Extended Amygdala: Implications for Social Behavior
Swann, J. M., Fabre‐Nys, C., & Barton, R. A. (2009) · Elsevier eBooks · doi:10.1016/b978-008088783-8.00012-7 · Cited by 10
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Hayes, L. J., & Delgado, D. (2006) · Behavior Genetics · doi:10.1007/s10519-006-9126-z · Cited by 10
Arginine Vasopressin 1a Receptor (AVPR1a) RS3 Repeat Polymorphism Associated with EntrepreneurshipPreprint
Wernerfelt, N., Rand, D. G., Dreber, A., Montgomery, C., & Malhotra, D. K. (2012) · SSRN Electronic Journal · doi:10.2139/ssrn.2141598 · Cited by 11
Penta, P. T., Villarreal, S., Rameas, C. I., Collins, E. C., Towner, T. T., Varlinskaya, E. I., & Werner, D. F. (2024) · Alcohol · doi:10.1016/j.alcohol.2024.10.001 · Cited by 9
Woodson, J., & Bergan, J. F. (2023) · The Journal of Comparative Neurology · doi:10.1002/cne.25476 · Cited by 9
Loss of oxytocin receptors in hilar mossy cells impairs social discrimination
Hung, Y.-C., Wu, Y., Chien, M.-E., Lin, Y., Tsai, C., & Hsu, K. (2023) · Neurobiology of Disease · doi:10.1016/j.nbd.2023.106311 · Cited by 10
The Role of Vasopressin in Anxiety and Depression
Morales‐Medina, J. C., Witchey, S. K., & Caldwell, H. K. (2016) · Springer eBooks · doi:10.1007/978-81-322-2803-5_40 · Cited by 9
Higuchi, Y., & Arakawa, H. (2022) · Hormones and Behavior · doi:10.1016/j.yhbeh.2022.105128 · Cited by 9
The Science of Expertise: Behavioral, Neural, and Genetic Approaches to Complex Skill
Plomin, R. (2017) · doi:10.4324/9781315113371 · Cited by 9
Landgraf, R., & Holsboer, F. (2005) · Drug Development Research · doi:10.1002/ddr.20022 · Cited by 9
Development of a radioligand for imaging V 1a vasopressin receptors with PET
Naik, R., Valentine, H., Hall, A., Mathews, W. B., Harris, J. C., Carter, C. S., Dannals, R. F., Wong, D. F., & Horti, A. G. (2017) · European Journal of Medicinal Chemistry · doi:10.1016/j.ejmech.2017.08.037 · Cited by 9
Arakawa, H., & Higuchi, Y. (2022) · Neuroscience & Biobehavioral Reviews · doi:10.1016/j.neubiorev.2022.104597 · Cited by 8
Bortolozzo-Gleich, M. H., Bouisset, G., Geng, L., Pino, A. R., Nomura, Y., Han, S., Li, Y., & Leroy, F. (2025) · Nature Communications · doi:10.1038/s41467-025-61994-6 · Cited by 10
Neumann, I. D. (2008) · Springer eBooks · doi:10.1007/978-3-540-79288-8_7 · Cited by 8
Sanctis, C. D., Bellenchi, G. C., & Viggiano, D. (2018) · Psychiatry Research · doi:10.1016/j.psychres.2018.01.036 · Cited by 8
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Metadata
- Authors
- Bielsky, I. F., Hu, S.-B., Szegda, K. L., Westphal, H., & Young, L. J.
- Affiliations
- Emory University (US)
- National Institutes of Health (US)
- Corresponding author
- Bielsky, Isadora F
- ORCID
- Young, Larry J
- Venue
- Neuropsychopharmacology
- Published
- 2003-11-26
- Volume
- 29
- Issue
- 3
- Pages
- 483-493
- ISSN
- 0893-133X (ISSN-L)
- 1740-634X
- OpenAlex
- W2084931825
- Cited by
- 531
- References
- 52
- Citations by year
- 2026: 16 · 2025: 13 · 2024: 14 · 2023: 20 · 2022: 26 · 2021: 24 · 2020: 15 · 2019: 20 · 2018: 19 · 2017: 26 · 2016: 21 · 2015: 21 · 2014: 35 · 2013: 30 · 2012: 25
- FWCI
- 32.89
- Type
- journal article
- Language
- en
- Open access
- closed
- Licence
- www.springer.com/tdm (tdm)
- Locations
- Neuropsychopharmacology (publishedVersion)
- PubMed (publishedVersion)
- Funders
- National Science Foundation (9876754)
- National Institutes of Health (NIH-R01, IBN-9876754, RR‐00165)
- National Institute of Mental Health (K02MH064692, R01 MH56897, K02 MH64692, R01MH056897)
- National Center for Research Resources (RR-00 165, P51RR000165)
- Topics
- Life Sciences › Neuroscience › Endocrine and Autonomic Systems › Neuroendocrine regulation and behavior
- Life Sciences › Neuroscience › Cellular and Molecular Neuroscience › Neuropeptides and Animal Physiology
- Life Sciences › Neuroscience › Cellular and Molecular Neuroscience › Neurotransmitter Receptor Influence on Behavior
- Keywords
- vasopressin, vasopressin V1a receptor, knockout mice, social recognition, anxiety-like behavior, oxytocin, social behavior, emotionality, autism spectrum disorder, anxiety disorders, stereotypy, olfactory learning and memory
- MeSH terms
- Animals, Anxiety, Female, Genotype, Male, Mice, Inbred C57BL, Social Behavior, Receptors, Vasopressin, Mice, Knockout, Maze Learning, Recognition, Psychology, Mice
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