Cited by 8Neuroendocrine regulation and behaviorOlfactory and Sensory Function StudiesNeuropeptides and Animal Physiology

Exocrine scent marking: coordinative role of arginine vasopressin in the systemic regulation of social signaling behaviors

Arakawa, Hiroyuki, Higuchi, Yuki·2022·Neuroscience & Biobehavioral Reviews

Abstract

Arginine vasopressin (AVP) is a neurohypophysial hormone that coordinatively regulates central socio-emotional behavior and peripheral control of antidiuretic fluid homeostasis. Most mammals, including rodents, utilize exocrine or urine-contained scent marking as a social signaling tool that facilitates social adaptation. The exocrine scent marking behavior is postulated to fine-tune sensory and cognitive abilities to recognize key social features via exocrine/urinary olfactory cues and subsequently control exocrine deposition or urinary marking through the mediation of osmotic fluid balance. AVP is implicated as a major player in controlling both recognition and signaling responses. This review provides constructive hypotheses on the coordinative processes of the AVP neurohypophysial circuits in the systemic regulations of fluid control and social-communicative behavior, via the expression of exocrine scent marking, and further emphasizes a potential role of AVP in a common mechanism underlying social communication in rodents.

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Crossref · 10.1016/j.neubiorev.2022.104597

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188 of 188 references verified0 citation errors · 0 not checkable

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  • Some behavioral effects of oxytocin and vasopressin are functionally linked to their peripheral function: oxytocin promotes birth and nursing but also parental nurturing, while vasopressin modulates urine production and also territorial behavior involving urine and scent marking.

    “Some of the behavioral effects of OXT and AVP are functionally linked to their peripheral function, as OXT promotes birth and nursing but also parental nurturing, while AVP modulates urine production and also territorial behavior, which often involves urine and scent marking (17,18).”

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Authors
Arakawa, H., & Higuchi, Y.
Affiliations
University of the Ryukyus (JP)
Venue
Neuroscience & Biobehavioral Reviews
Publisher
Elsevier BV
Published
2022-05
Volume
136
Pages
104597
ISSN
0149-7634 (ISSN-L)
OpenAlex
W4214812366
Cited by
8
References
189
Citations by year
2026: 3 · 2025: 1 · 2024: 1 · 2023: 1 · 2022: 2
FWCI
0.19
Type
journal article
Language
en
Open access
closed
Locations
  • Neuroscience & Biobehavioral Reviews (publishedVersion)
  • PubMed (publishedVersion)
Funders
Japan Society for the Promotion of Science
Topics
  • Social Sciences › Psychology › Social Psychology › Neuroendocrine regulation and behavior
  • Life Sciences › Neuroscience › Sensory Systems › Olfactory and Sensory Function Studies
  • Life Sciences › Neuroscience › Cellular and Molecular Neuroscience › Neuropeptides and Animal Physiology
Keywords
vasopressin, urine marking, social signaling, social communication, osmoregulation, fluid homeostasis, olfactory cues, rodents, social recognition
MeSH terms
Animals, Arginine Vasopressin, Humans, Mammals, Odorants, Smell, Social Behavior

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