Clinically approved liposomal nanomedicines: lessons learned from the biomolecular corona
Abstract
The biomolecular corona that forms around liposomes in vivo does confer on them a selective targeting ability.
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The targeting capability of PCSN could be partly linked with some serum proteins recruited at the surface of PCSN.
“Considering that apolipoproteins on nanoparticle play an important role in association with cellular uptake to target cells32–34, targeting capability of PCSN partly could be linked with some serum proteins recruited at the surface of PCSN.”
From Cloaking nanoparticles with protein corona shield for targeted drug delivery. (2018) · cites this paper as [33]
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- Authors
- Caracciolo, G.
- Affiliations
- Sapienza University of Rome (IT)
- Corresponding author
- Caracciolo, Giulio
- ORCID
- Caracciolo, Giulio
- Venue
- Nanoscale
- Publisher
- Royal Society of Chemistry (RSC)
- Published
- 2018
- Volume
- 10
- Issue
- 9
- Pages
- 4167-4172
- ISSN
- 2040-3364 (ISSN-L)
- 2040-3372
- OpenAlex
- W2787356256
- Cited by
- 106
- References
- 61
- Citations by year
- 2026: 6 · 2025: 7 · 2024: 11 · 2023: 8 · 2022: 14 · 2021: 15 · 2020: 15 · 2019: 20 · 2018: 10
- FWCI
- 4.49
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- Nanoscale (publishedVersion)
- PubMed (publishedVersion)
- IRIS Research product catalog (Sapienza University of Rome) (submittedVersion)
- Topics
- Physical Sciences › Materials Science › Biomaterials › Nanoparticle-Based Drug Delivery
- Life Sciences › Biochemistry, Genetics and Molecular Biology › Molecular Biology › Lipid Membrane Structure and Behavior
- Life Sciences › Biochemistry, Genetics and Molecular Biology › Molecular Biology › Extracellular vesicles in disease
- Keywords
- liposomes, biomolecular corona, PEGylation, targeted drug delivery, liposome design, off-target interactions, personalized nanomedicine, tumor targeting, plasma proteins, liposome physicochemical properties
- MeSH terms
- Protein Corona, Humans, Liposomes, Polyethylene Glycols, Drug Delivery Systems, Nanomedicine
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