Student or educator? Sign up with your school email and get 6 months of Pro free.
Cited by 41

The DOI matches its Crossref record; 15 of the 15 references it cites were found in a registry or an index.

Bifunctional ligand design for modulating mutant p53 aggregation in cancer

Miller, Jessica J., Blanchet, Anaïs, Orvain, Christophe, Nouchikian, Lucienne, Reviriot, Yasmin, Clarke, Ryan M., Martelino, Diego, Wilson, Derek, Gaiddon, Christian, Storr, Tim·2019·Chemical Science

Abstract

Iodination of a bifunctional ligand framework restores p53 function by interacting with and inhibiting mutant p53 aggregation.

Overview

The claims and statistics of this paper haven’t been checked yet.

Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.

A few free checks a day · papers already verified open instantly · results are public

Integrity signals

Registry

Crossref · 10.1039/c9sc04151f

Cites

15 of 15 references verified0 citation errors · 0 not checkable

Statistics

Verification

Claims the paper makes

The claims and statistics of this paper haven’t been checked yet.

Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.

A few free checks a day · papers already verified open instantly · results are public

Claims other papers make about this one

Each is checked against this paper’s own text: does it say what the citing paper says it does?

Self-check

Percentages, sums and reported differences re-computed from the paper’s own numbers.

The self-check needs the paper’s full text.

Citations

Cites

Show all 15 references

Research works printed but not linked: 110

  1. Geschwind, 2015, Continuum, 21, 1612
  2. Eisenberg, 2017, Annu. Rev. Biochem., 86, 69, 10.1146/annurev-biochem-061516-045104 · DOI · Paper page
  3. Chiti, 2017, Annu. Rev. Biochem., 86, 27, 10.1146/annurev-biochem-061516-045115 · DOI · Paper page
  4. DeToma, 2012, Chem. Soc. Rev., 41, 608, 10.1039/C1CS15112F · DOI · Paper page
  5. Eisenberg, 2012, Cell, 148, 1188, 10.1016/j.cell.2012.02.022 · DOI · Paper page
  6. Chen, 2010, Alzheimer's Dementia, 6, e44, 10.1016/j.jalz.2010.08.135 · DOI
  7. Sowade, 2017, Nat. Commun., 8, 512, 10.1038/s41467-017-00579-4 · DOI
  8. Xu, 2011, Nat. Chem. Biol., 7, 285, 10.1038/nchembio.546 · DOI · Paper page
  9. Hao, 2015, Curr. Protein Pept. Sci., 16, 135, 10.2174/1389203715666141128115649 · doi:10.2174/1389203715666141128115649
  10. Rangel, 2014, Prion, 8, 75, 10.4161/pri.27776 · DOI
  11. Ishimaru, 2003, Biochemistry, 42, 9022, 10.1021/bi034218k · DOI · Paper page
  12. Ano Bom, 2012, J. Biol. Chem., 287, 28152, 10.1074/jbc.M112.340638 · DOI · Paper page
  13. Lasagna-Reeves, 2013, Biochem. Biophys. Res. Commun., 430, 963, 10.1016/j.bbrc.2012.11.130 · DOI
  14. Silva, 2014, Trends Biochem. Sci., 39, 260, 10.1016/j.tibs.2014.04.001 · DOI · Paper page
  15. Kehrloesser, 2016, Cell Death Differ., 23, 1952, 10.1038/cdd.2016.75 · DOI
  16. Costa, 2016, Cold Spring Harbor Perspect. Biol., 8, a023614, 10.1101/cshperspect.a023614 · DOI
  17. Joerger, 2016, Annu. Rev. Biochem., 85, 375, 10.1146/annurev-biochem-060815-014710 · DOI · Paper page
  18. Lazo, 2017, Cell. Signalling, 33, 49, 10.1016/j.cellsig.2017.02.005 · DOI
  19. Lane, 1992, Nature, 358, 15, 10.1038/358015a0 · DOI · Paper page
  20. Loh, 2010, Metallomics, 2, 442, 10.1039/c003915b · DOI
  21. Wang, 2012, Proc. Natl. Acad. Sci. U. S. A., 109, 13590, 10.1073/pnas.1211557109 · DOI · Paper page
  22. Vogelstein, 2000, Nature, 408, 307, 10.1038/35042675 · DOI · Paper page
  23. Muller, 2013, Nat. Cell Biol., 15, 2, 10.1038/ncb2641 · DOI · Paper page
  24. Hollstein, 1991, Science, 253, 49, 10.1126/science.1905840 · DOI · Paper page
  25. Wilcken, 2012, Proc. Natl. Acad. Sci. U. S. A., 109, 13584, 10.1073/pnas.1211550109 · DOI · Paper page
  26. Cino, 2016, Sci. Rep., 6, 32535, 10.1038/srep32535 · DOI
  27. Butler, 2003, Biochemistry, 42, 2396, 10.1021/bi026635n · DOI · Paper page
  28. D'Orazi, 2012, Cell Cycle, 11, 2581, 10.4161/cc.21020 · DOI
  29. Miller, 2018, Chem.–Eur. J., 24, 17734, 10.1002/chem.201802677 · DOI
  30. Wilcken, 2012, J. Am. Chem. Soc., 134, 6810, 10.1021/ja301056a · DOI · Paper page
  31. Chuikov, 2004, Nature, 432, 353, 10.1038/nature03117 · DOI · Paper page
  32. Joerger, 2015, Structure, 23, 2246, 10.1016/j.str.2015.10.016 · DOI
  33. Doveston, 2017, FEBS Lett., 591, 2449, 10.1002/1873-3468.12723 · DOI
  34. Amaral, 2019, Front. Chem., 7, a00015
  35. Hietanen, 2000, Proc. Natl. Acad. Sci. U. S. A., 97, 8501, 10.1073/pnas.97.15.8501 · DOI · Paper page
  36. Joerger, 2013, Nucleic Acids Res., 41, 6034, 10.1093/nar/gkt305 · DOI · Paper page
  37. Baud, 2018, Eur. J. Med. Chem., 152, 101, 10.1016/j.ejmech.2018.04.035 · DOI
  38. Blanden, 2015, Mol. Pharmacol., 87, 825, 10.1124/mol.114.097550 · DOI · Paper page
  39. Blanden, 2015, Drug Discovery Today, 20, 1391, 10.1016/j.drudis.2015.07.006 · DOI
  40. Yu, 2014, OncoTargets Ther., 5, 8879, 10.18632/oncotarget.2432 · DOI · Paper page
  41. Zaman, 2019, Mol. Cancer Ther., 8, 1355, 10.1158/1535-7163.MCT-18-1080 · DOI · Paper page
  42. Yu, 2017, Mol. Pharmacol., 91, 567, 10.1124/mol.116.107409 · DOI · Paper page
  43. Cirone, 2013, OncoImmunology, 2, e26198, 10.4161/onci.26198 · DOI
  44. Garufi, 2015, Int. J. Oncol., 47, 1241, 10.3892/ijo.2015.3125 · DOI
  45. Garufi, 2014, Cell Death Dis., 5, e1271, 10.1038/cddis.2014.217 · DOI
  46. Weekley, 2017, Curr. Opin. Chem. Biol., 37, 26, 10.1016/j.cbpa.2016.12.011 · DOI
  47. Stacy, 2016, J. Med. Chem., 59, 4965, 10.1021/acs.jmedchem.6b00238 · DOI · Paper page
  48. Park, 2016, Metallomics, 8, 874, 10.1039/C6MT00105J · DOI
  49. King, 2017, Inorg. Chem., 56, 6609, 10.1021/acs.inorgchem.7b00710 · DOI
  50. Akam, 2016, Bioconjugate Chem., 27, 1807, 10.1021/acs.bioconjchem.6b00332 · DOI
  51. Jones, 2017, Chem. Sci., 8, 5636, 10.1039/C7SC01269A · DOI
  52. Sharma, 2018, Front. Pharmacol., 9, 1247, 10.3389/fphar.2018.01247 · DOI
  53. Savelieff, 2019, Chem. Rev., 119, 1221, 10.1021/acs.chemrev.8b00138 · DOI · Paper page
  54. Rangel, 2019, J. Biol. Chem., 3670, 10.1074/jbc.RA118.004671 · DOI
  55. Ferraz da Costa, 2018, OncoTargets Ther., 9, 29112, 10.18632/oncotarget.25631 · DOI
  56. Kanapathipillai, 2018, Cancers, 10, 154, 10.3390/cancers10060154 · DOI · Paper page
  57. Zhaolin, 2017, Protein Pept. Lett., 24, 353, 10.2174/0929866524666170123142858 · doi:10.2174/0929866524666170123142858
  58. Chen, 2017, Biochem. Biophys. Res. Commun., 489, 130, 10.1016/j.bbrc.2017.05.111 · DOI
  59. Silva, 2018, Acc. Chem. Res., 51, 181, 10.1021/acs.accounts.7b00473 · DOI
  60. Morphy, 2005, J. Med. Chem., 48, 6523, 10.1021/jm058225d · DOI · Paper page
  61. Levy, 2011, Int. J. Biochem. Cell Biol., 43, 60, 10.1016/j.biocel.2010.10.017 · DOI · Paper page
  62. Ghosh, 2017, Cell Death Differ., 24, 1784, 10.1038/cdd.2017.105 · DOI
  63. Burdette, 2001, J. Am. Chem. Soc., 123, 7831, 10.1021/ja010059l · DOI · Paper page
  64. Chang, 2004, Chem. Biol., 11, 203, 10.1016/j.chembiol.2004.01.017 · DOI
  65. Xu, 2010, Chem. Soc. Rev., 39, 1996, 10.1039/b916287a · DOI · Paper page
  66. Ami, 2013, Microb. Cell Fact., 12, 17, 10.1186/1475-2859-12-17 · doi:10.1186/1475-2859-12-17
  67. Rodrigues, 1990, Proc. Natl. Acad. Sci. U. S. A., 87, 7555, 10.1073/pnas.87.19.7555 · DOI · Paper page
  68. Lane, 1990, Genes Dev., 4, 1, 10.1101/gad.4.1.1 · DOI · Paper page
  69. Oren, 2010, Cold Spring Harbor Perspect. Biol., 2, a001107, 10.1101/cshperspect.a001107 · DOI · Paper page
  70. Rotter, 1983, Proc. Natl. Acad. Sci. U. S. A., 80, 2613, 10.1073/pnas.80.9.2613 · DOI
  71. Kayed, 2003, Science, 300, 486, 10.1126/science.1079469 · DOI · Paper page
  72. Fine, 1967, Am. J. Clin. Pathol., 47, 588, 10.1093/ajcp/47.5.588 · DOI
  73. Xu, 2011, Nat. Chem. Biol., 7, 285, 10.1038/nchembio.546 · DOI · Paper page
  74. Auffinger, 2004, Proc. Natl. Acad. Sci. U. S. A., 101, 16789, 10.1073/pnas.0407607101 · DOI · Paper page
  75. Shah, 2017, ACS Chem. Biol., 12, 1204, 10.1021/acschembio.7b00056 · DOI
  76. Erdélyi, 2017, Biochemistry, 56, 2759, 10.1021/acs.biochem.7b00371 · DOI
  77. Bullock, 1997, Proc. Natl. Acad. Sci. U. S. A., 94, 14338, 10.1073/pnas.94.26.14338 · DOI · Paper page
  78. A. E. Martell and R. D.Hancock , Metal Complexes in Aqueous Solutions , Springer , New York, US , 1996 · DOI · Paper page
  79. Harris, 1979, J. Am. Chem. Soc., 101, 6097, 10.1021/ja00514a037 · DOI · Paper page
  80. Gee, 2002, Cell Calcium, 31, 245, 10.1016/S0143-4160(02)00053-2 · DOI
  81. Carraway, 2012, Biochim. Biophys. Acta, 1823, 544, 10.1016/j.bbamcr.2011.09.013 · doi:10.1016/j.bbamcr.2011.09.013
  82. Hoe, 2014, Nat. Rev. Drug Discovery, 13, 217, 10.1038/nrd4236 · DOI · Paper page
  83. Macleod, 1995, Genes Dev., 9, 935, 10.1101/gad.9.8.935 · DOI · Paper page
  84. Benson, 2014, Oncogene, 33, 3959, 10.1038/onc.2013.378 · DOI · Paper page
  85. Gaiddon, 2001, Mol. Cell. Biol., 21, 1874, 10.1128/MCB.21.5.1874-1887.2001 · DOI · Paper page
  86. Li, 2007, Oncogene, 26, 2220, 10.1038/sj.onc.1210311 · DOI · Paper page
  87. Pietsch, 2008, Oncogene, 27, 6507, 10.1038/onc.2008.315 · DOI · Paper page
  88. Fenoglio-Preiser, 2003, Hum. Mutat., 21, 258, 10.1002/humu.10180 · DOI · Paper page
  89. Mosmann, 1983, J. Immunol. Methods, 65, 55, 10.1016/0022-1759(83)90303-4 · DOI · Paper page
  90. Zhu, 2013, World J. Surg. Oncol., 11, 22, 10.1186/1477-7819-11-22 · DOI
  91. Sayan, 2008, Oncogene, 27, 4363, 10.1038/onc.2008.64 · DOI
  92. Liu, 2011, Mol. Cancer, 10, 95, 10.1186/1476-4598-10-95 · doi:10.1186/1476-4598-10-95
  93. Frank, 2011, Cancer Biol. Ther., 11, 740, 10.4161/cbt.11.8.14906 · DOI · Paper page
  94. Bergamaschi, 2003, Cancer Cell, 3, 387, 10.1016/S1535-6108(03)00079-5 · DOI · Paper page
  95. Marin, 2000, Nat. Genet., 25, 47, 10.1038/75586 · DOI · Paper page
  96. Elmore, 2007, Toxicol. Pathol., 35, 495, 10.1080/01926230701320337 · DOI · Paper page
  97. Candé, 2004, Cell Death Differ., 11, 591, 10.1038/sj.cdd.4401400 · DOI · Paper page
  98. Sevrioukova, 2011, Antioxid. Redox Signaling, 14, 2545, 10.1089/ars.2010.3445 · DOI · Paper page
  99. Shen, 2012, Clin. Cancer Res., 18, 1561, 10.1158/1078-0432.CCR-11-3040 · DOI
  100. Hientz, 2016, OncoTargets Ther., 8, 8921, 10.18632/oncotarget.13475 · DOI · Paper page
  101. Zhou, 2018, J. Mol. Cell Biol., 11, 293, 10.1093/jmcb/mjy072 · DOI · Paper page
  102. Blandino, 1999, Oncogene, 18, 477, 10.1038/sj.onc.1202314 · DOI · Paper page
  103. Siddik, 2003, Oncogene, 22, 7265, 10.1038/sj.onc.1206933 · DOI · Paper page
  104. Perlman, 1999, Cell Death Differ., 6, 48, 10.1038/sj.cdd.4400453 · DOI · Paper page
  105. Walensky, 2019, Nat. Chem. Biol., 15, 657, 10.1038/s41589-019-0306-6 · DOI
  106. Pearce, 2017, PLoS One, 12, e0184360, 10.1371/journal.pone.0184360 · DOI · Paper page
  107. Cheok, 2012, Cell Cycle, 11, 2227, 10.4161/cc.20961 · doi:10.4161/cc.20961
  108. van Leeuwen, 2012, Cell Cycle, 11, 1851, 10.4161/cc.20254 · doi:10.4161/cc.20254
  109. Lane, 2010, Cold Spring Harbor Perspect. Biol., 2, a001222, 10.1101/cshperspect.a001222 · DOI · Paper page
  110. Wallach, 2017, J. Pediatr. Gastroenterol. Nutr., 64, 180, 10.1097/MPG.0000000000001411 · DOI

Cited by

See all 41

Metadata

Authors
Miller, J. J., Blanchet, A., Orvain, C., Nouchikian, L., Reviriot, Y., Clarke, R. M., Martelino, D., Wilson, D., Gaiddon, C., & Storr, T.
Venue
Chemical Science
Published
2019
Volume
10
Issue
46
Pages
10802-10814
ISSN
  • 2041-6520
  • 2041-6539
Cited by
41
References
15
Language
en
Funders
  • Michael Smith Foundation for Health Research
  • Natural Sciences and Engineering Research Council of Canada
  • Simon Fraser University
  • Centre National de la Recherche Scientifique
  • Institut National de la Santé et de la Recherche Médicale
  • Association pour la Recherche sur le Cancer

About these checks

Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.

Statistics and arithmetic are recomputed, not judged.

Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.

What counts as a claim ›How we measure confidence ›How we check this ›

Are you an author, or do you see a problem with this page? Request a review

How to cite

Cite CoChat for the checks on this page, and the paper for its own findings.

This page
CoChat. (2026). Citation check: Bifunctional ligand design for modulating mutant p53 aggregation in cancer. https://app.cochat.ai/papers/10.1039/c9sc04151f
The paper
Miller, J. J., Blanchet, A., Orvain, C., Nouchikian, L., Reviriot, Y., Clarke, R. M., Martelino, D., Wilson, D., Gaiddon, C., & Storr, T. (2019). Bifunctional ligand design for modulating mutant p53 aggregation in cancer. Chemical Science. https://doi.org/10.1039/c9sc04151f

Data sources

Bibliographic data: Semantic Scholar, OpenAlex, Crossref.

Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).

Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.