Increased Adipose Tissue Expression of Hepcidin in Severe Obesity Is Independent From Diabetes and NASH

Obesity is associated with macrophage accumulation in adipose tissue

Weisberg, S. P., McCann, D., Desai, M., Rosenbaum, M., Leibel, R. L., & Ferrante, A. W. (2003) · Journal of Clinical Investigation · doi:10.1172/jci200319246 · Cited by 10,041

Chronic inflammation in fat plays a crucial role in the development of obesity-related insulin resistance

Xu, H., Barnes, G. T., Yang, Q., Tan, G., Yang, D., Chou, C. J., Sole, J., Nichols, A., Ross, J. S., Tartaglia, L. A., et al. (2003) · Journal of Clinical Investigation · doi:10.1172/jci200319451 · Cited by 6,760

Hepcidin Regulates Cellular Iron Efflux by Binding to Ferroportin and Inducing Its Internalization

Nemeth, E., Tuttle, M. S., Powelson, J., Vaughn, M. B., Donovan, A., Ward, D. M., Ganz, T., & Kaplan, J. (2004) · Science · doi:10.1126/science.1104742 · Cited by 4,803

IL-6 mediates hypoferremia of inflammation by inducing the synthesis of the iron regulatory hormone hepcidin

Nemeth, E., Rivera, S., Gabayan, V., Keller, C., Taudorf, S., Pedersen, B. K., & Ganz, T. (2004) · Journal of Clinical Investigation · doi:10.1172/jci200420945 · Cited by 2,650

C-Reactive Protein in Healthy Subjects: Associations With Obesity, Insulin Resistance, and Endothelial Dysfunction: A Potential Role for Cytokines Originating From Adipose Tissue?

Yudkin, J. S., Stehouwer, C. D. A., Emeis, J. J., & Coppack, S. W. (1999) · Arteriosclerosis, Thrombosis, and Vascular Biology · doi:10.1161/01.atv.19.4.972 · Cited by 2,465

Adipokines: inflammation and the pleiotropic role of white adipose tissue

Trayhurn, P., & Wood, I. S. (2004) · British Journal of Nutrition · doi:10.1079/bjn20041213 · Cited by 2,210

Inflammation: the link between insulin resistance, obesity and diabetes

Dandona, P. (2004) · Trends in Immunology · doi:10.1016/j.it.2003.10.013 · Cited by 2,170

Hepcidin, a urinary antimicrobial peptide synthesized in the liver

Park, C. H., Valore, E. V., Waring, A. J., & Ganz, T. (2001) · Journal of Biological Chemistry · doi:10.1074/jbc.m008922200 · Cited by 2,168

Subcutaneous Adipose Tissue Releases Interleukin-6, But Not Tumor Necrosis Factor-α,in Vivo1

Mohamed‐Ali, V., Goodrick, S., Rawesh, A., Katz, D. R., Miles, J. M., Yudkin, J. S., Klein, S., & Coppack, S. W. (1997) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/jcem.82.12.4450 · Cited by 2,032

A New Mouse Liver-specific Gene, Encoding a Protein Homologous to Human Antimicrobial Peptide Hepcidin, Is Overexpressed during Iron Overload

Pigeon, C., Ilyin, G., Courselaud, B., Leroyer, P., Turlin, B., Brissot, P., & Loréal, O. (2001) · Journal of Biological Chemistry · doi:10.1074/jbc.m008923200 · Cited by 1,697

Iron deficiency anaemia

Lopez, A., Cacoub, P., Macdougall, I. C., & Peyrin‐Biroulet, L. (2015) · The Lancet · doi:10.1016/s0140-6736(15)60865-0 · Cited by 1,603

Iron bioavailability and dietary reference values

Hurrell, R., & Egli, I. (2010) · The American Journal of Clinical Nutrition · doi:10.3945/ajcn.2010.28674f · Cited by 1,359

Hepcidin and iron homeostasis

Ganz, T., & Nemeth, E. (2012) · Biochimica et Biophysica Acta (BBA) - Molecular Cell Research · doi:10.1016/j.bbamcr.2012.01.014 · Cited by 1,282

Systemic Iron Homeostasis

Ganz, T. (2013) · Physiological Reviews · doi:10.1152/physrev.00008.2013 · Cited by 1,122

Low-grade inflammation, diet composition and health: current research evidence and its translation

Minihane, A. M., Vinoy, S., Russell, W. R., Baka, A., Roche, H. M., Tuohy, K. M., Teeling, J. L., Blaak, E. E., Fenech, M. F., Vauzour, D., et al. (2015) · British Journal Of Nutrition · doi:10.1017/s0007114515002093 · Cited by 962

Nonalcoholic Fatty Liver Disease: Pathology and Pathogenesis

Tiniakos, D. G., Vos, M. B., & Brunt, E. M. (2010) · Annual Review of Pathology: Mechanisms of Disease · doi:10.1146/annurev-pathol-121808-102132 · Cited by 870

Iron metabolism and iron disorders revisited in the hepcidin era

Camaschella, C., Nai, A., & Silvestri, L. (2020) · Haematologica · doi:10.3324/haematol.2019.232124 · Cited by 734

Iron Homeostasis and Ferroptosis in Human Diseases: Mechanisms and Therapeutic Prospects

Ru, Q., Li, Y., Chen, L., Wu, Y., Min, J., & Wang, F. (2024) · Signal Transduction and Targeted Therapy · doi:10.1038/s41392-024-01969-z · Cited by 724

Adipose Tissue: The New Endocrine Organ? A Review Article

Wozniak, S. E., Gee, L. L., Wachtel, M. S., & Frezza, E. E. (2008) · Digestive Diseases and Sciences · doi:10.1007/s10620-008-0585-3 · Cited by 607

Adipokines as emerging mediators of immune response and inflammation

Lago, F., Diéguez, C., Gómez-Reino, J. J., & Gualillo, O. (2007) · Nature Clinical Practice Rheumatology · doi:10.1038/ncprheum0674 · Cited by 569

Serum Ferritin Is An Independent Predictor of Histologic Severity and Advanced Fibrosis in Patients With Nonalcoholic Fatty Liver Disease

Kowdley, K. V., Belt, P. H., Wilson, L., Yeh, M. M., Neuschwander‐Tetri, B. A., Chalasani, N., Sanyal, A. J., & Nelson, J. E. (2011) · Hepatology · doi:10.1002/hep.24706 · Cited by 552

Iron and diabetes risk

Simcox, J. A., & McClain, D. A. (2013) · Cell Metabolism · doi:10.1016/j.cmet.2013.02.007 · Cited by 545

Hepcidin and disorders of iron metabolism

Ganz, T., & Nemeth, E. (2011) · Annual Review of Medicine · doi:10.1146/annurev-med-050109-142444 · Cited by 466

The emerging role of adipokines as mediators of inflammation and immune responses

Lago, F., Diéguez, C., Gómez-Reino, J. J., & Gualillo, O. (2007) · Cytokine & Growth Factor Reviews · doi:10.1016/j.cytogfr.2007.04.007 · Cited by 373

Relationship between the pattern of hepatic iron deposition and histological severity in nonalcoholic fatty liver disease

Nelson, J. E., Wilson, L., Brunt, E. M., Yeh, M. M., Kleiner, D. E., Ünalp–Arida, A., & Kowdley, K. V. (2010) · Hepatology · doi:10.1002/hep.24038 · Cited by 362

Molecular Signatures of Obstructive Sleep Apnea in Adults: A Review and Perspective

Arnardóttir, E. S., Mackiewicz, M., Gíslason, Þ., Teff, K. L., & Pack, A. I. (2009) · SLEEP · doi:10.1093/sleep/32.4.447 · Cited by 355

Childhood Dual Burden of Under- and Overnutrition in Low- and Middle-inCome Countries: A Critical Review

Tzioumis, E., & Adair, L. S. (2014) · Food and Nutrition Bulletin · doi:10.1177/156482651403500210 · Cited by 364

Inflammation and iron deficiency in the hypoferremia of obesity

Yanoff, L. B., Menzie, C. M., Denkinger, B., Sebring, N. G., McHugh, T., Remaley, A. T., & Yanovski, J. A. (2007) · International Journal of Obesity · doi:10.1038/sj.ijo.0803625 · Cited by 341

Adipocyte iron regulates adiponectin and insulin sensitivity

Gabrielsen, J. S., Gao, Y. M., Simcox, J., Huang, J., Thorup, D., Jones, D., Cooksey, R. C., Gabrielsen, D. A., Adams, T. D., Hunt, S. C., et al. (2012) · Journal of Clinical Investigation · doi:10.1172/jci44421 · Cited by 339

Obesity as an emerging risk factor for iron deficiency

Aigner, E., Feldman, A., & Datz, C. (2014) · Nutrients · doi:10.3390/nu6093587 · Cited by 328

Iron Overload Cardiomyopathy

Gujja, P., Rosing, D. R., Tripodi, D. J., & Shizukuda, Y. (2010) · Journal of the American College of Cardiology · doi:10.1016/j.jacc.2010.03.083 · Cited by 334

Hepcidin: from discovery to differential diagnosis

Kemna, E., Tjalsma, H., Willems, H. L., & Swinkels, D. W. (2007) · Haematologica · doi:10.3324/haematol.11705 · Cited by 318

Serum hepcidin: reference ranges and biochemical correlates in the general population

Galesloot, T. E., Vermeulen, S. H., Geurts-Moespot, A. J., Klaver, S. M., Kroot, J. J., van Tienoven, D., Wetzels, J. F. M., Kiemeney, L. A. L. M., Sweep, F. C., den Heijer, M., et al. (2011) · Blood · doi:10.1182/blood-2011-02-337907 · Cited by 303

(n-3) Fatty Acids Alleviate Adipose Tissue Inflammation and Insulin Resistance: Mechanistic Insights

Kalupahana, N. S., Claycombe, K. J., & Moustaid-Moussa, N. (2011) · Advances in Nutrition · doi:10.3945/an.111.000505 · Cited by 305

An overview of molecular basis of iron metabolism regulation and the associated pathologies

Silva, B., & Faustino, P. (2015) · Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease · doi:10.1016/j.bbadis.2015.03.011 · Cited by 300

Obesity and iron deficiency: A quantitative meta-analysis

Zhao, L., Zhang, X., Shen, Y., Fang, X., Wang, Y., & Wang, F. (2015) · Obesity Reviews · doi:10.1111/obr.12323 · Cited by 286

The burden of obesity on infectious disease

Karlsson, E. A., & Beck, M. A. (2010) · Experimental Biology and Medicine · doi:10.1258/ebm.2010.010227 · Cited by 296

Revisiting the adipocyte: a model for integration of cytokine signaling in the regulation of energy metabolism

Rodríguez, A., Ezquerro, S., Méndez-Giménez, L., Becerril, S., & Frühbeck, G. (2015) · American Journal of Physiology-Endocrinology and Metabolism · doi:10.1152/ajpendo.00297.2015 · Cited by 287

The Pig as an Experimental Model for Elucidating the Mechanisms Governing Dietary Influence on Mineral Absorption

Patterson, J. K., Lei, X. G., & Miller, D. D. (2008) · Experimental Biology and Medicine · doi:10.3181/0709-mr-262 · Cited by 267

Hepcidin in Human Iron Disorders: Diagnostic Implications

Kroot, J. J., Tjalsma, H., Fleming, R. E., & Swinkels, D. W. (2011) · Clinical Chemistry · doi:10.1373/clinchem.2009.140053 · Cited by 246

Hepatic Expression Patterns of Inflammatory and Immune Response Genes Associated with Obesity and NASH in Morbidly Obese Patients

Bertola, A., Bonnafous, S., Anty, R., Patouraux, S., Saint-Paul, M.-C., Iannelli, A., Gugenheim, J., Barr, J., Mato, J. M., Le Marchand-Brustel, Y., et al. (2010) · PLoS ONE · doi:10.1371/journal.pone.0013577 · Cited by 240

Adiposity in women and children from transition countries predicts decreased iron absorption, iron deficiency and a reduced response to iron fortification

Zimmermann, M. B., Zeder, C., Muthayya, S., Winichagoon, P., Chaouki, N., Aeberli, I., & Hurrell, R. F. (2008) · International Journal of Obesity · doi:10.1038/ijo.2008.43 · Cited by 225

The hematologic consequences of obesity

Purdy, J. C., & Shatzel, J. J. (2021) · European Journal Of Haematology · doi:10.1111/ejh.13560 · Cited by 227

Sharply higher rates of iron deficiency in obese Mexican women and children are predicted by obesity-related inflammation rather than by differences in dietary iron intake

Cepeda-Lopez, A. C., Osendarp, S. J. M., Melse‐Boonstra, A., Herter‐Aeberli, I., González‐Salazar, F., Feskens, E. J. M., Villalpando, S., & Zimmermann, M. B. (2011) · American Journal of Clinical Nutrition · doi:10.3945/ajcn.110.005439 · Cited by 230

17β-Estradiol Inhibits Iron Hormone Hepcidin Through an Estrogen Responsive Element Half-Site

Yang, Q., Jian, J., Katz, S., Abramson, S. B., & Huang, X. (2012) · Endocrinology · doi:10.1210/en.2011-2045 · Cited by 208

Hepcidin Regulation of Iron Transport

Collins, J. F., Wessling‐Resnick, M., & Knutson, M. D. (2008) · Journal of Nutrition · doi:10.3945/jn.108.096347 · Cited by 201

Hepcidin in Obese Children as a Potential Mediator of the Association between Obesity and Iron Deficiency

del Giudice, E. M., Santoro, N., Amato, A., Brienza, C., Calabrò, P., Wiegerinck, E. T. G., Cirillo, G., Tartaglione, N., Grandone, A., Swinkels, D. W., et al. (2009) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/jc.2009-1361 · Cited by 201

Out of Balance—Systemic Iron Homeostasis in Iron-Related Disorders

Steinbicker, A. U., & Muckenthaler, M. U. (2013) · Nutrients · doi:10.3390/nu5083034 · Cited by 201

Overweight children have higher circulating hepcidin concentrations and lower iron status but have dietary iron intakes and bioavailability comparable with normal weight children

Herter‐Aeberli, I., Hurrell, R. F., & Zimmermann, M. B. (2009) · International Journal of Obesity · doi:10.1038/ijo.2009.146 · Cited by 195

Nutritional consequences of adjustable gastric banding and gastric bypass: A 1-year prospective study

Coupaye, M., Puchaux, K., Bogard, C., Msika, S., Jouet, P., Clerici, C., Larger, E., & Ledoux, S. (2009) · Obesity Surgery · doi:10.1007/s11695-008-9571-2 · Cited by 190

Pathways underlying iron accumulation in human nonalcoholic fatty liver disease

Aigner, E., Theurl, I., Theurl, M., Lederer, D., Haufe, H., Dietze, O., Strasser, M., Datz, C., & Weiss, G. (2008) · The American Journal of Clinical Nutrition · doi:10.1093/ajcn/87.5.1374 · Cited by 190

Iron deficiency and obesity: the contribution of inflammation and diminished iron absorption

McClung, J. P., & Karl, J. P. (2009) · Nutrition Reviews · doi:10.1111/j.1753-4887.2008.00145.x · Cited by 189

Leptin Increases the Expression of the Iron Regulatory Hormone Hepcidin in HuH7 Human Hepatoma Cells

Chung, B., Matak, P., McKie, A. T., & Sharp, P. (2007) · Journal of Nutrition · doi:10.1093/jn/137.11.2366 · Cited by 188

Is Obesity Associated With Anemia of Chronic Disease? A Population‐based Study

Ausk, K. J., & Ioannou, G. N. (2008) · Obesity · doi:10.1038/oby.2008.353 · Cited by 187

Iron homeostasis in the metabolic syndrome

Datz, C., Felder, T. K., Niederseer, D., & Aigner, E. (2013) · European Journal of Clinical Investigation · doi:10.1111/eci.12032 · Cited by 181

The liver: conductor of systemic iron balance

Meynard, D., Babitt, J. L., & Lin, H. Y.-F. (2013) · Blood · doi:10.1182/blood-2013-06-427757 · Cited by 181

Obesity Alters Adipose Tissue Macrophage Iron Content and Tissue Iron Distribution

Orr, J. S., Kennedy, A. J., Anderson‐Baucum, E. K., Webb, C. D., Fordahl, S. C., Erikson, K. M., Zhang, Y., Etzerodt, A., Moestrup, S. K., & Hasty, A. H. (2013) · Diabetes · doi:10.2337/db13-0213 · Cited by 172

Iron and Immunity: Immunological Consequences of Iron Deficiency and Overload

Cherayil, B. J. (2010) · Archivum Immunologiae et Therapiae Experimentalis · doi:10.1007/s00005-010-0095-9 · Cited by 170

Review article: the iron overload syndromes

Siddique, A., & Kowdley, K. V. (2012) · Alimentary Pharmacology & Therapeutics · doi:10.1111/j.1365-2036.2012.05051.x · Cited by 162

Rethinking Iron Regulation and Assessment in Iron Deficiency, Anemia of Chronic Disease, and Obesity: Introducing Hepcidin

Tussing-Humphreys, L. M., Pustacioglu, C., Nemeth, E., & Braunschweig, C. L. (2012) · Journal of the Academy of Nutrition and Dietetics · doi:10.1016/j.jada.2011.08.038 · Cited by 171

Elevated Systemic Hepcidin and Iron Depletion in Obese Premenopausal Females

Tussing-Humphreys, L. M., Nemeth, E., Fantuzzi, G., Freels, S. A., Guzman, G., Holterman, A. L., & Braunschweig, C. L. (2009) · Obesity · doi:10.1038/oby.2009.319 · Cited by 170

The relationship between obesity and hypoferraemia in adults: A systematic review

Cheng, H. L., Bryant, C., Cook, R., O'Connor, H., Rooney, K., & Steinbeck, K. (2012) · Obesity Reviews · doi:10.1111/j.1467-789x.2011.00938.x · Cited by 159

Elevated Expression of Osteopontin May Be Related to Adipose Tissue Macrophage Accumulation and Liver Steatosis in Morbid Obesity

Bertola, A., Deveaux, V., Bonnafous, S., Rousseau, D., Anty, R., Wakkach, A., Dahman, M., Tordjman, J., Clément, K., McQuaid, S., et al. (2008) · Diabetes · doi:10.2337/db08-0400 · Cited by 150

Iron and non-alcoholic fatty liver disease

Britton, L., Subramaniam, V., & Crawford, D. (2016) · World Journal of Gastroenterology · doi:10.3748/wjg.v22.i36.8112 · Cited by 136

Evidence for differential effects of hepcidin in macrophages and intestinal epithelial cells

Chaston, T., Chung, B., Mascarenhas, M., Marks, J., Patel, B., Srai, S. K., & Sharp, P. (2008) · Gut · doi:10.1136/gut.2007.131722 · Cited by 145

The impact of maternal obesity on iron status, placental transferrin receptor expression and hepcidin expression in human pregnancy

Garcia-Valdes, L., Campoy, C., Hayes, H. E., Florido, J., Rusanova, I., León, M. T. M., & McArdle, H. J. (2015) · International Journal of Obesity · doi:10.1038/ijo.2015.3 · Cited by 147

Estrogen Regulates Hepcidin Expression via GPR30-BMP6-Dependent Signaling in Hepatocytes

Ikeda, Y., Tajima, S., Izawa-Ishizawa, Y., Kihira, Y., Ishizawa, K., Tomita, S., Tsuchiya, K., & Tamaki, T. (2012) · PLoS ONE · doi:10.1371/journal.pone.0040465 · Cited by 140

Genetics, genetic testing, and management of hemochromatosis: 15 years since hepcidin

Pietrangelo, A. (2015) · Gastroenterology · doi:10.1053/j.gastro.2015.06.045 · Cited by 136

Hepcidin, the iron watcher

Viatte, L., & Vaulont, S. (2009) · Biochimie · doi:10.1016/j.biochi.2009.06.012 · Cited by 140

CD44 is a key player in non-alcoholic steatohepatitis

Patouraux, S., Rousseau, D., Bonnafous, S., Lebeaupin, C., Luci, C., Canivet, C. M., Schneck, A.-S., Bertola, A., Saint‐Paul, M., Iannelli, A., et al. (2017) · Journal of Hepatology · doi:10.1016/j.jhep.2017.03.003 · Cited by 139

A high visceral adipose tissue-to-skeletal muscle ratio as a determinant of major complications after pancreatoduodenectomy for cancer

Sandini, M., Bernasconi, D. P., Fior, D., Molinelli, M., Ippolito, D., Nespoli, L. C., Caccialanza, R., & Gianotti, L. V. (2016) · Nutrition · doi:10.1016/j.nut.2016.04.002 · Cited by 130

Current approach to hemochromatosis

Brissot, P., Troadec, M., Bardou‐Jacquet, E., Lan, C. L., Jouanolle, A., Deugnier, Y., & Loréal, O. (2008) · Blood Reviews · doi:10.1016/j.blre.2008.03.001 · Cited by 132

The Liver in Regulation of Iron Homeostasis

Rishi, G., & Subramaniam, V. N. (2017) · American Journal of Physiology-Gastrointestinal and Liver Physiology · doi:10.1152/ajpgi.00004.2017 · Cited by 124

Gluconeogenic Signals Regulate Iron Homeostasis via Hepcidin in Mice

Vecchi, C., Montosi, G., Garuti, C., Corradini, E., Sabelli, M., Canali, S., & Pietrangelo, A. (2013) · Gastroenterology · doi:10.1053/j.gastro.2013.12.016 · Cited by 123

Excess Adiposity, Inflammation, and Iron-Deficiency in Female Adolescents

Tussing-Humphreys, L. M., Liang, H., Nemeth, E., Freels, S. A., & Braunschweig, C. A. (2009) · Journal of the American Dietetic Association · doi:10.1016/j.jada.2008.10.044 · Cited by 127

Epidemiological associations between iron and cardiovascular disease and diabetes

Basuli, D., Stevens, R. G., Torti, F. M., & Torti, S. V. (2014) · Frontiers in Pharmacology · doi:10.3389/fphar.2014.00117 · Cited by 124

Iron Metabolism in Nonalcoholic Fatty Liver Disease

Nelson, J. E., Klintworth, H. M., & Kowdley, K. V. (2011) · Current Gastroenterology Reports · doi:10.1007/s11894-011-0234-4 · Cited by 119

High-fat diet causes iron deficiency via hepcidin-independent reduction of duodenal iron absorption

Sonnweber, T., Ress, C., Nairz, M., Theurl, I., Schroll, A., Murphy, A. T., Wroblewski, V., Witcher, D. R., Moser, P., Ebenbichler, C. F., et al. (2012) · The Journal of Nutritional Biochemistry · doi:10.1016/j.jnutbio.2011.10.013 · Cited by 117

Hepcidin modulation in human diseases: From research to clinic

Piperno, A., Mariani, R., Trombini, P., & Girelli, D. (2009) · World Journal of Gastroenterology · doi:10.3748/wjg.15.538 · Cited by 117

Dysregulation of iron and copper homeostasis in nonalcoholic fatty liver

Aigner, E. S. (2014) · World Journal of Hepatology · doi:10.4254/wjh.v7.i2.177 · Cited by 116

Intra-individual Variation of Plasma Adipokine Levels and Utility of Single Measurement of These Biomarkers in Population-Based Studies

Lee, S., Kallianpur, A. R., Xiang, Y., Wen, W., Cai, Q., Liu, D., Fazio, S., Linton, M. F., Zheng, W., & Shu, X. O. (2007) · Cancer Epidemiology Biomarkers & Prevention · doi:10.1158/1055-9965.epi-07-0374 · Cited by 110

In overweight and obese women, dietary iron absorption is reduced and the enhancement of iron absorption by ascorbic acid is one-half that in normal-weight women

Cepeda-Lopez, A. C., Melse‐Boonstra, A., Zimmermann, M. B., & Herter‐Aeberli, I. (2015) · American Journal of Clinical Nutrition · doi:10.3945/ajcn.114.099218 · Cited by 112

Iron, glucose and fat metabolism and obesity: an intertwined relationship

Hilton, C., Sabaratnam, R., Drakesmith, H., & Karpe, F. (2023) · International Journal of Obesity · doi:10.1038/s41366-023-01299-0 · Cited by 113

Hepcidin and iron-related gene expression in subjects with Dysmetabolic Hepatic Iron Overload

Barisani, D., Pelucchi, S., Mariani, R., Galimberti, S., Trombini, P., Fumagalli, D., Meneveri, R., Nemeth, E., Ganz, T., & Piperno, A. (2008) · Journal of Hepatology · doi:10.1016/j.jhep.2008.03.011 · Cited by 111

Decreased serum hepcidin and improved functional iron status 6 months after restrictive bariatric surgery

Tussing‐Humphreys, L. M., Nemeth, E., Fantuzzi, G., Freels, S., Holterman, A. L., Galvani, C., Ayloo, S., Vitello, J., & Braunschweig, C. (2010) · Obesity · doi:10.1038/oby.2009.490 · Cited by 105

Obesity during pregnancy and fetal iron status: is Hepcidin the link?

Dao, M. C., Sen, S., Iyer, C., Klebenov, D., & Meydani, S. N. (2012) · Journal of Perinatology · doi:10.1038/jp.2012.81 · Cited by 107

Iron and Neurodegeneration: Is Ferritinophagy the Link?

Biasiotto, G., Lorenzo, D. D., Archetti, S., & Zanella, I. (2015) · Molecular Neurobiology · doi:10.1007/s12035-015-9473-y · Cited by 105

Long-term Evolution of Nutritional Deficiencies After Gastric Bypass

Ledoux, S., Calabrese, D., Bogard, C., Dupré, T., Castel, B., Msika, S., Larger, É., & Coupaye, M. (2013) · Annals of Surgery · doi:10.1097/sla.0000000000000249 · Cited by 104

Erythroferrone: An Erythroid Regulator of Hepcidin and Iron Metabolism

Coffey, R., & Ganz, T. (2018) · HemaSphere · doi:10.1097/hs9.0000000000000035 · Cited by 112

Innate Immunity and Host Defense Peptides in Veterinary Medicine

Linde, A., Ross, C. R., Davis, E. G., Dib, L. H., Blecha, F., & Melgarejo, T. (2008) · Journal of Veterinary Internal Medicine · doi:10.1111/j.1939-1676.2007.0038.x · Cited by 100

Anaemia, iron deficiency and susceptibility to infections

Jonker, F. A. M., & van Hensbroek, M. B. (2014) · Journal of Infection · doi:10.1016/j.jinf.2014.08.007 · Cited by 110

The iron-regulatory hormone hepcidin: A possible therapeutic target?

Rochette, L., Gudjoncik, A., Guénancia, C., Zeller, M., Cottin, Y., & Vergely, C. (2014) · Pharmacology & Therapeutics · doi:10.1016/j.pharmthera.2014.09.004 · Cited by 104

Role of Serum Uric Acid and Ferritin in the Development and Progression of NAFLD

Lombardi, R., Pisano, G., & Fargion, S. R. (2016) · International Journal of Molecular Sciences · doi:10.3390/ijms17040548 · Cited by 98

Iron and the liver: Update 2008

Deugnier, Y., Brissot, P., & Loréal, O. (2008) · Journal of Hepatology · doi:10.1016/j.jhep.2008.01.014 · Cited by 98

Interacting signals in the control of hepcidin expression

Darshan, D., & Anderson, G. J. (2009) · BioMetals · doi:10.1007/s10534-008-9187-y · Cited by 95

Iron in obesity. An ancient micronutrient for a modern disease

Zafón, C., Lecube, A., & Simó, R. (2009) · Obesity Reviews · doi:10.1111/j.1467-789x.2009.00638.x · Cited by 96

Gender-related variations in iron metabolism and liver diseases

Harrison-Findik, D. D. (2010) · World Journal of Hepatology · doi:10.4254/wjh.v2.i8.302 · Cited by 105

Serum ferritin levels are associated with vascular damage in patients with nonalcoholic fatty liver disease

Valenti, L. V. C., Swinkels, D. W., Burdick, L., Dongiovanni, P., Tjalsma, H., Motta, B. M., Bertelli, C., Fatta, E., Bignamini, D., Rametta, R., et al. (2010) · Nutrition Metabolism and Cardiovascular Diseases · doi:10.1016/j.numecd.2010.01.003 · Cited by 93

Hepatic iron is the major determinant of serum ferritin in NAFLD patients

Ryan, J. D., Armitage, A. E., Cobbold, J., Banerjee, R., Borsani, O., Dongiovanni, P., Neubauer, S., Morovat, R., Wang, L. M., Pasricha, S., et al. (2017) · Liver International · doi:10.1111/liv.13513 · Cited by 93

Increased Serum Hepcidin Levels in Subjects with the Metabolic Syndrome: A Population Study

Martinelli, N., Traglia, M., Campostrini, N., Biino, G., Corbella, M., Sala, C. F., Busti, F., Masciullo, C., Manna, D., Previtali, S., et al. (2012) · PLoS ONE · doi:10.1371/journal.pone.0048250 · Cited by 90

Iron absorption in dysmetabolic iron overload syndrome is decreased and correlates with increased plasma hepcidin

Ruivard, M., Lainé, F., Ganz, T., Olbina, G., Westerman, M., Nemeth, E., Rambeau, M., Mazur, A., Gerbaud, L., Tournilhac, V., et al. (2009) · Journal of Hepatology · doi:10.1016/j.jhep.2009.01.029 · Cited by 89

Iron overload and cofactors with special reference to alcohol, hepatitis C virus infection and steatosis/insulin resistance

Kohgo, Y. (2007) · World Journal of Gastroenterology · doi:10.3748/wjg.v13.i35.4699 · Cited by 91

New insights into the links between hypoxia and iron homeostasis

Renassia, C., & Peyssonnaux, C. (2019) · Current Opinion in Hematology · doi:10.1097/moh.0000000000000494 · Cited by 98

Serum Hepcidin and Macrophage Iron Correlate With MCP-1 Release and Vascular Damage in Patients With Metabolic Syndrome Alterations

Valenti, L. V. C., Dongiovanni, P., Motta, B. M., Swinkels, D. W., Bonara, P., Rametta, R., Burdick, L., Frugoni, C., Fracanzani, A. L., & Fargion, S. R. (2010) · Arteriosclerosis Thrombosis and Vascular Biology · doi:10.1161/atvbaha.110.214858 · Cited by 88

Targeted disruption of hepcidin in the liver recapitulates the hemochromatotic phenotype

Zumerle, S., Mathieu, J. R. R., Delga, S., Heinis, M., Viatte, L., Vaulont, S., & Peyssonnaux, C. (2014) · Blood · doi:10.1182/blood-2014-01-550467 · Cited by 87

Iron deficiency and anaemia in bariatric surgical patients: causes, diagnosis and proper management.

Múñoz, M., Romero, F. B., Gómez‐Ramírez, S., Campos, A., & García‐Erce, J. A. (2009) · PubMed · doi:10.3305/nh.2009.24.6.4547 · Cited by 87

Hepcidin is localised in gastric parietal cells, regulates acid secretion and is induced by Helicobacter pylori infection

Schwarz, P., Kübler, J., Strnad, P., Müller, K., Barth, T. F. E., Gerloff, A., Feick, P., Peyssonnaux, C., Vaulont, S., Adler, G., et al. (2011) · Gut · doi:10.1136/gut.2011.241208 · Cited by 86

Obesity modulate serum hepcidin and treatment outcome of iron deficiency anemia in children: A case control study

Sanad, M., Osman, M., & Gharib, A. (2011) · Italian Journal of Pediatrics · doi:10.1186/1824-7288-37-34 · Cited by 85

Serum Markers of Hepatocyte Death and Apoptosis Are Non Invasive Biomarkers of Severe Fibrosis in Patients with Alcoholic Liver Disease

Lavallard, V., Bonnafous, S., Patouraux, S., Saint‐Paul, M., Rousseau, D., Anty, R., MARCHAND‐BRUSTEL, Y. L., Tran, A., & Gual, P. (2011) · PLoS ONE · doi:10.1371/journal.pone.0017599 · Cited by 85

Role of nutrition on anemia in elderly

Bianchi, V. E. (2015) · Clinical Nutrition ESPEN · doi:10.1016/j.clnesp.2015.09.003 · Cited by 85

Mice That Are Fed a High-Fat Diet Display Increased Hepcidin Expression in Adipose Tissue

GOTARDO, E. R. M. F., dos Santos, A. N., Miyashiro, R. A., Gambero, S., Rocha, T., Ribeiro, M. L., & Gambero, A. (2013) · Journal of Nutritional Science and Vitaminology · doi:10.3177/jnsv.59.454 · Cited by 47

Summary

Vokurka, M., Lacinová, Z., Křemen, J., Kopecky, P., Bláha, J., Pelinková, K., Haluzík, M., & Nečas, E. (2009)

Hepcidin is expressed in adipose tissue and its expression is increased in severely obese patients independently from diabetes and NASH

Gual, P., Bekri, S., Anty, R., Luciani, N., Dahman, M., Ramesh, B., Paul, M., Huet, P., Sadoul, J., Gugenheim, J., et al. (2006) · UCL Discovery (University College London)

Increased Expression of Hepcidin in Obese Patients: Impact on Phenotypic Expression of Hemochromatosis and Pathophysiology of Dysmetabolic Iron Overload Syndrome

Lainé, F., & Deugnier, Y. (2006) · Gastroenterology · doi:10.1053/j.gastro.2006.10.046 · Cited by 16

Adipocyte Hypoxia Increases Hepatocyte Hepcidin Expression

Hintze, K. J., Snow, D. R., Nabor, D., & Timbimboo, H. (2010) · Biological Trace Element Research · doi:10.1007/s12011-010-8932-6 · Cited by 21