The DOI matches its Crossref record; 243 of the 247 references it cites were found in a registry or an index.
Inflammation and Colon Cancer
Abstract
The connection between inflammation and tumorigenesis is well-established and in the last decade has received a great deal of supporting evidence from genetic, pharmacological, and epidemiological data. Inflammatory bowel disease is an important risk factor for the development of colon cancer. Inflammation is also likely to be involved with other forms of sporadic as well as heritable colon cancer. The molecular mechanisms by which inflammation promotes cancer development are still being uncovered and could differ between colitis-associated and other forms of colorectal cancer. Recent work has elucidated the role of distinct immune cells, cytokines, and other immune mediators in virtually all steps of colon tumorigenesis, including initiation, promotion, progression, and metastasis. These mechanisms, as well as new approaches to prevention and therapy, are discussed in this review.
Overview
Integrity signals
Registry
Cites
Statistics
Verification
Claims the paper makes
Claims other papers make about this one
Each is checked against this paper’s own text: does it say what the citing paper says it does?
In the citing paper
“There is evidence that a link between inflammation and colorectal cancer exists.”
From Hyaluronic a cid–doxorubicin nanoparticles for targeted treatment of colorectal cancer (2021) · cites this paper as [98]
In the citing paper
“Chronic intestinal inflammation has been associated with the development of CRC and it can result from an aberrant ratio of protective (tolerogenic) to aggressive (proinflammatory, pro-tumorigenic) microbiota [45] .”
From Intestinal microbiota in health and disease: Role of bifidobacteria in gut homeostasis (2014) · cites this paper as [45]
In the citing paper
“Many bacterial species were found to be enriched in colorectal tumour samples and adjacent tissue: B. fragilis, Bacteroides vulgatus, Bifidobacterium longum, Clostridium butyricum, Mitsuokella multiacida, E. coli, Enterococcus faecalis, and S. bovis [45] .”
From Intestinal microbiota in health and disease: Role of bifidobacteria in gut homeostasis (2014) · cites this paper as [45]
Citations
Cites
A genetic model for colorectal tumorigenesis
Fearon, E. R., & Vogelstein, B. (1990) · Cell · doi:10.1016/0092-8674(90)90186-i · Cited by 12,132
Mantovani, A., Allavena, P., Sica, A., & Balkwill, F. (2008) · Nature · doi:10.1038/nature07205 · Cited by 11,399
Immunity, Inflammation, and Cancer
Grivennikov, S. I., Greten, F. R., & Karin, M. (2010) · Cell · doi:10.1016/j.cell.2010.01.025 · Cited by 10,755
Self-citationThe basics of epithelial-mesenchymal transition
Kalluri, R., & Weinberg, R. A. (2009) · Journal of Clinical Investigation · doi:10.1172/jci39104 · Cited by 10,196
Jemal, A., Siegel, R. L., Ward, E., Hao, Y., Xu, J., Murray, T., & Thun, M. J. (2008) · CA A Cancer Journal for Clinicians · doi:10.3322/ca.2007.0010 · Cited by 10,184
Bettelli, E., Carrier, Y., Gao, W., Korn, T., Strom, T. B., Oukka, M., Weiner, H. L., & Kuchroo, V. K. (2006) · Nature · doi:10.1038/nature04753 · Cited by 6,992
Myeloid-derived-suppressor cells as regulators of the immune system
Gabrilovich, D. I., & Nagaraj, S. (2009) · Nature Reviews Immunology · doi:10.1038/nri2506 · Cited by 6,753
Type, Density, and Location of Immune Cells Within Human Colorectal Tumors Predict Clinical Outcome
Galon, J., Costes, A., Sanchez-Cabo, F., Kirilovsky, A., Mlecnik, B., Lagorce-Pagès, C., Tosolini, M., Camus, M., Berger, A., Wind, P., et al. (2006) · Science · doi:10.1126/science.1129139 · Cited by 6,516
Metagenomic Analysis of the Human Distal Gut Microbiome
Gill, S. R., Pop, M., DeBoy, R. T., Eckburg, P. B., Turnbaugh, P. J., Samuel, B. S., Gordon, J. I., Relman, D. A., Fraser-Liggett, C. M., & Nelson, K. E. (2006) · Science · doi:10.1126/science.1124234 · Cited by 4,699
STATs in cancer inflammation and immunity: a leading role for STAT3
Yu, H., Pardoll, D., & Jove, R. (2009) · Nature reviews. Cancer · doi:10.1038/nrc2734 · Cited by 4,383
Cited by
Sorted by citations
Items 901–1,000 of 1,003
El‐Fadeal, N. M. A., Nafie, M. S., El-Kherbetawy, M. K., Elmistekawy, A., Mohammad, H. M. F., Elbahaie, A. M., Hashish, A. A., Alomar, S. Y., Aloyouni, S. Y., El-dosoky, M., et al. (2021) · International Journal of Molecular Sciences · doi:10.3390/ijms22105213 · Cited by 24
A Signaling View into the Inflammatory Tumor Microenvironment
Pereira, J., Jordan, P., & Matos, P. (2021) · Immuno · doi:10.3390/immuno1020007 · Cited by 24
Hua, X., Kratz, M., Malen, R. C., Dai, J. Y., Lindström, S., Zheng, Y., & Newcomb, P. A. (2021) · British Journal of Cancer · doi:10.1038/s41416-021-01458-y · Cited by 24
Microbiome in drug resistance to colon cancer
Pandey, K. R., & Umar, S. (2021) · Current Opinion in Physiology · doi:10.1016/j.cophys.2021.100472 · Cited by 24
Nag, S., & Saha, K. D. (2021) · ACS Omega · doi:10.1021/acsomega.1c03477 · Cited by 24
Tajasuwan, L., Kettawan, A., Rungruang, T., Wunjuntuk, K., Prombutara, P., Muangnoi, C., & Kettawan, A. K. (2022) · Foods · doi:10.3390/foods11213488 · Cited by 24
Boytar, A. N., Nitert, M. D., Morrison, M., Skinner, T. L., & Jenkins, D. G. (2022) · The Journal of Physiology · doi:10.1113/jp283702 · Cited by 28
Application of chitosan as nano carrier in the treatment of inflammatory bowel disease
Liu, X., Dong, Y., Wang, C., & Guo, Z. (2024) · International Journal of Biological Macromolecules · doi:10.1016/j.ijbiomac.2024.134899 · Cited by 24
Inactivation of the Transcription Factor GLI1 Accelerates Pancreatic Cancer Progression
Mills, L. D., Zhang, L., Marler, R. J., Svingen, P. A., Fernández‐Barrena, M. G., Dave, M., Bamlet, W. R., McWilliams, R. R., Petersen, G. M., Faubion, W. A., et al. (2014) · Journal of Biological Chemistry · doi:10.1074/jbc.m113.539031 · Cited by 24
From Molecular Biology to Clinical Trials: Toward Personalized Colorectal Cancer Therapy
Palma, S., Zwenger, A. O., Croce, M. V., Abba, M. C., & Lacunza, E. (2015) · Clinical Colorectal Cancer · doi:10.1016/j.clcc.2015.11.001 · Cited by 25
Association Between Dietary Inflammation Index and The Risk of Colorectal Cancer: A Meta-Analysis
Zhang, C., Wang, W., & Zhang, D. (2017) · Nutrition and Cancer · doi:10.1080/01635581.2017.1374418 · Cited by 24
Kuhn, B. R., Brat, C., Fettel, J., Hellmuth, N., Maucher, I. V., Bulut, U., Hock, K. J., Grimmer, J., Manolikakes, G., Rühl, M., et al. (2018) · Biochemical Pharmacology · doi:10.1016/j.bcp.2018.06.014 · Cited by 25
Li, G., Zhang, J., Liu, Z., Wang, Q., Chen, Y., Liu, M., Li, D., Han, J., & Wang, B. (2019) · Journal of Inorganic Biochemistry · doi:10.1016/j.jinorgbio.2019.02.011 · Cited by 24
Zhang, Y., Zhu, J., Huang, G., Zhu, J., & He, D. (2020) · Carbon · doi:10.1016/j.carbon.2020.02.029 · Cited by 24
SIRT5 Contributes to Colorectal Cancer Growth by Regulating T Cell Activity
Wang, K., Hu, Z., Zhang, C., Yang, L., Li, F., Yang, P., & Yu, H. (2020) · Journal of Immunology Research · doi:10.1155/2020/3792409 · Cited by 24
Jin, H., Gao, S., Song, D., Liu, Y., & Chen, X. (2020) · Anti-Cancer Drugs · doi:10.1097/cad.0000000000001000 · Cited by 24
Endometrial polyps in infertile patients: do high concentrations of interferon-gamma play a role?
Mollo, A., Stile, A., Alviggi, C., Granata, M., Placido, G. D., Perrella, A., D'Antonio, A., & Cicinelli, E. (2011) · Fertility and Sterility · doi:10.1016/j.fertnstert.2011.08.001 · Cited by 24
Cao, X., Li, L., Hu, J., Zhu, S., Song, S., Kong, S., Zhou, L., & Huang, Y. (2024) · The Journal of Nutritional Biochemistry · doi:10.1016/j.jnutbio.2024.109804 · Cited by 23
Colorectal cancer mouse models: Integrating inflammation and the stroma
Ernst, M., & Ramsay, R. G. (2011) · Journal of Gastroenterology and Hepatology · doi:10.1111/j.1440-1746.2011.06883.x · Cited by 23
Blood cell markers that can predict the long-term outcomes of patients with colorectal cancer
Mizuno, H., Yuasa, N., Takeuchi, E., Miyake, H., Nagai, H., Yoshioka, Y., & Miyata, K. (2019) · PLoS ONE · doi:10.1371/journal.pone.0220579 · Cited by 23
Sankaranarayanan, R., Kumar, D. R., Patel, J., & Bhat, G. J. (2020) · Molecules · doi:10.3390/molecules25092243 · Cited by 23
Non‐genetic biomarkers and colorectal cancer risk: Umbrella review and evidence triangulation
Zhang, X., Gill, D., He, Y., Yang, T., Li, X., Monori, G., Campbell, H. J., Dunlop, M. G., Tsilidis, K. K., Timofeeva, M. N., et al. (2020) · Cancer Medicine · doi:10.1002/cam4.3051 · Cited by 22
Chan, Y., Lai, W., Chen, J., Tseng, J. T.-C., Chuang, P.-C., Jou, J., Lee, C., & Sun, H. S. (2020) · Cancers · doi:10.3390/cancers12071844 · Cited by 23
Impact of Appendectomy on Gut Microbiota
Бабаханов, А. Т., ДЖУМАБЕКОВ, А. Т., Zhao, A., Kuandykov, Y., Tanabayeva, S. B., Fakhradiyev, I. R., Nazarenko, Y., & Saliev, T. M. (2021) · Surgical Infections · doi:10.1089/sur.2020.422 · Cited by 26
Suppression of ELF4 in ulcerative colitis predisposes host to colorectal cancer
Du, H., Xia, H., Liu, T., Li, Y., Liu, J., Xie, B., Chen, J., Liu, T., Cao, L., Liu, S., et al. (2021) · iScience · doi:10.1016/j.isci.2021.102169 · Cited by 22
B cell-mediated regulatory mechanisms control tumor-promoting intestinal inflammation
Melcher, C., Yu, J., Duong, V. H. H., Westphal, K., Farimany, N. H. S., Shaverskyi, A., Zhao, B., Strowig, T., Glage, S., Brand, K., et al. (2022) · Cell Reports · doi:10.1016/j.celrep.2022.111051 · Cited by 25
Enterobacter Strains Might Promote Colon Cancer
Yurdakul, D., Karataş, A. Y., & Şahi̇n, F. (2015) · Current Microbiology · doi:10.1007/s00284-015-0867-x · Cited by 22
Rodríguez-Pérez, C. E., Nie, W., Sinnett‐Smith, J. W., Rozengurt, E., & Yoo, J. (2011) · American Journal of Physiology-Gastrointestinal and Liver Physiology · doi:10.1152/ajpgi.00381.2010 · Cited by 23
Ahmed, F., Kumari, S., & Kondapi, A. K. (2018) · Pharmaceutical Research · doi:10.1007/s11095-018-2457-7 · Cited by 24
miR-21: a promising biomarker for the early detection of colon cancer
Dehghan, F., Boozarpour, S., Torabizadeh, Z., & Alijanpour, S. (2019) · OncoTargets and Therapy · doi:10.2147/ott.s199508 · Cited by 23
Sonowal, H., & Ramana, K. V. (2020) · Current Medicinal Chemistry · doi:10.2174/0929867327666201027152737 · Cited by 23
Afzal, S. M., Vafa, A., Rashid, S., Barnwal, P., Shahid, A., Shree, A., Islam, J., Ali, N., & Sultana, S. (2020) · Environmental Toxicology · doi:10.1002/tox.23068 · Cited by 23
Mezzapelle, R., Marchis, F. D., Passera, C., Leo, M., Brambilla, F., Colombo, F., Casalgrandi, M., Preti, A., Zambrano, S., Castellani, P., et al. (2021) · EMBO Molecular Medicine · doi:10.15252/emmm.202012344 · Cited by 21
Gut microbiota: an Indicator to Gastrointestinal Tract Diseases
Patel, T., Bhattacharya, P., & Das, S. (2016) · Journal of Gastrointestinal Cancer · doi:10.1007/s12029-016-9820-x · Cited by 26
Gut microbiota protect against colorectal tumorigenesis through lncRNA Snhg9
Wang, M., Liu, K., Bao, W., Hang, B., Chen, X., Zhu, X., Li, G., Liu, L., Xiang, H., Hu, H., et al. (2025) · Developmental Cell · doi:10.1016/j.devcel.2024.12.013 · Cited by 24
Kangwan, N., Kim, Y. T., Han, Y., Jeong, M., Park, J., & Hahm, K. (2015) · International Journal of Cancer · doi:10.1002/ijc.29892 · Cited by 22
The Role and Underlying Mechanism of miR-1299 in Cancer
Deng, K., Huang, L., Sun, X., & Zang, Y. (2021) · Future Science OA · doi:10.2144/fsoa-2021-0014 · Cited by 22
Charan, T. R., Bhutto, M. A., Bhutto, M. A., Tunio, A. A., Khuhro, G. M., Khaskheli, S. A., & Mughal, A. A. (2021) · Future Journal of Pharmaceutical Sciences · doi:10.1186/s43094-021-00281-9 · Cited by 22
Antitumor and hepatoprotective effect of Cuscuta reflexa Roxb. in a murine model of colon cancer
Mishra, S., Alhodieb, F. S., Barkat, M. A., Hassan, M. Z., Barkat, H. A., Ali, R., Alam, P., & Alam, O. (2021) · Journal of Ethnopharmacology · doi:10.1016/j.jep.2021.114597 · Cited by 24
Sharma, B. R., Karki, R., Sundaram, B., Wang, Y., Vogel, P., & Kanneganti, T. (2022) · Cancers · doi:10.3390/cancers14040919 · Cited by 20
Martínez-Gutiérrez, A. D., Carbajal-López, B., Bui, T. M., Mendoza-Rodríguez, M., Campos-Parra, A. D., Calderillo-Ruiz, G., León, D. F. C.-D., Madrigal‐Santillán, E., Sumagin, R., Pérez‐Plasencia, C., et al. (2022) · Biochemistry and Biophysics Reports · doi:10.1016/j.bbrep.2022.101252 · Cited by 22
Sugamata, N., Okuyama, T., Takeshita, E., Oi, H., Hakozaki, Y., Miyazaki, S., Takada, M., Mitsui, T., Noro, T., Yoshitomi, H., et al. (2022) · World Journal of Surgical Oncology · doi:10.1186/s12957-022-02578-2 · Cited by 22
Bischoff, N. S., Proquin, H., Jetten, M. J., Schrooders, Y., Jonkhout, M. C. M., Briedé, J. J., van Breda, S. G., Jennen, D. G. J., Medina‐Reyes, E. I., Delgado‐Buenrostro, N. L., et al. (2022) · Nanomaterials · doi:10.3390/nano12081256 · Cited by 22
Yao, H., Wang, S., Zhou, X., Sun, J., Zhou, G., Zhou, D., Chen, G., Shi, X., Chen, J., Shi, B., et al. (2022) · Journal of Gastrointestinal Oncology · doi:10.21037/jgo-22-957 · Cited by 22
Contribution of natural killer cells in innate immunity against colorectal cancer
Ghazvinian, Z., Abdolahi, S., Tokhanbigli, S., Tarzemani, S., Piccin, A., Zali, M. R., Verdi, J., & Baghaei, K. (2023) · Frontiers in Oncology · doi:10.3389/fonc.2022.1077053 · Cited by 23
Li, D., Liu, W., Wang, X., Wu, J., Quan, W., Yao, Y., Bals, R., Ji, S., Wu, K., Guo, J., et al. (2014) · Oncotarget · doi:10.18632/oncotarget.2845 · Cited by 22
Human Pol ɛ-dependent replication errors and the influence of mismatch repair on their correction
Agbor, A. A., Goksenin, A. Y., LeCompte, K. G., Hans, S. H., & Pursell, Z. F. (2013) · DNA repair · doi:10.1016/j.dnarep.2013.08.012 · Cited by 22
Inflammatory cues acting on the adult intestinal stem cells and the early onset of cancer (Review)
Barbaro, A. D. L., Perletti, G., Bonapace, I. M., & Monti, E. (2014) · International Journal of Oncology · doi:10.3892/ijo.2014.2490 · Cited by 22
Valerii, M. C., Benaglia, M., Caggiano, C., Papi, A., Strillacci, A., Lazzarini, G., Campieri, M., Gionchetti, P., Rizzello, F., & Spisni, E. (2012) · Nanomedicine Nanotechnology Biology and Medicine · doi:10.1016/j.nano.2012.11.007 · Cited by 22
Urokinase-Type Plasminogen Activator Deficiency Promotes Neoplasmatogenesis in the Colon of Mice
Karamanavi, E., Angelopoulou, K., Lavrentiadou, S. N., Tsingotjidou, A., Abas, Z., Taitzoglou, I., Vlemmas, I., Erdman, S. E., & Poutahidis, T. (2014) · Translational Oncology · doi:10.1016/j.tranon.2014.02.002 · Cited by 22
Dysregulation of laminins in intestinal inflammation
Spenlé, C., Hussenet, T., Lacroute, J., Lefèbvre, O., Kédinger, M., Orend, G., & Simon-Assmann, P. M. (2011) · Pathologie Biologie · doi:10.1016/j.patbio.2011.10.005 · Cited by 22
Böehm, K., Valdivieso, R. F., Meskawi, M., Larcher, A., Schiffmann, J., Sun, M., Graefen, M., Fred Saad, C., Parent, M., & Karakiewicz, P. I. (2015) · World Journal of Urology · doi:10.1007/s00345-015-1625-1 · Cited by 22
In silico and Ex vivo approaches identify a role for toll-like receptor 4 in colorectal cancer
Sussman, D. A., Santaolalla, R., Bejarano, P. A., Garcia-Buitrago, M. T., Perez, M. T., Abreu, M. T., & Clarke, J. (2014) · Journal of Experimental & Clinical Cancer Research · doi:10.1186/1756-9966-33-45 · Cited by 22
Piulats, J. M., Kondo, J., Endo, H., Ono, H., Hagihara, T., Okuyama, H., Nishizawa, Y., Tomita, Y., Ohue, M., Okita, K., et al. (2018) · Oncotarget · doi:10.18632/oncotarget.24641 · Cited by 22
FORMATION OF THE INTESTINAL MICROBIOTA OF CHILDREN AND THE FACTORS THAT INFLUENCE THIS PROCESS
Nikolaeva, I. V., Царегородцев, А. Д., & Shaikhieva, G. S. (2018) · Rossiyskiy Vestnik Perinatologii i Pediatrii (Russian Bulletin of Perinatology and Pediatrics) · doi:10.21508/1027-4065-2018-63-3-13-18 · Cited by 27
Herrera-R, A., Naranjo, T. W., Celis, M. E. M., Moreno, G., Yepes, A. F., & Cardona‐Galeano, W. (2019) · Medicinal Chemistry Research · doi:10.1007/s00044-019-02487-2 · Cited by 22
TLR9 induces colitis‑associated colorectal carcinogenesis by regulating NF‑κB expression levels
Luo, Q., Zeng, L., Tang, C., Zhang, Z., Chen, Y., & Zeng, C. (2020) · Oncology Letters · doi:10.3892/ol.2020.11971 · Cited by 24
Bioengineered Colorectal Cancer Drugs: Orally Delivered Anti-Inflammatory Agents
Urbanska, A. M., Zhang, X., & Prakash, S. (2015) · Cell Biochemistry and Biophysics · doi:10.1007/s12013-015-0528-5 · Cited by 22
Early life environment and developmental immunotoxicity in inflammatory dysfunction and disease
Leifer, C. A., & Dietert, R. R. (2011) · Toxicological & Environmental Chemistry Reviews · doi:10.1080/02772248.2011.586114 · Cited by 22
Ma, X., LvjunYan, Yu, X., Guo, H., He, Y., Wen, S., Yu, T., & Wang, W. (2024) · Journal of Functional Foods · doi:10.1016/j.jff.2024.106091 · Cited by 21
Zhang, J., Huang, L., & Xu, A. (2017) · Oncotarget · doi:10.18632/oncotarget.15497 · Cited by 21
Antidepressant Use and Risk of Colorectal Cancer in the Women's Health Initiative
Kiridly, J. F., Sturgeon, S. R., Kroenke, C. H., & Reeves, K. W. (2018) · Cancer Epidemiology Biomarkers & Prevention · doi:10.1158/1055-9965.epi-17-1035 · Cited by 21
Fiedler, D., Hirsch, D. D., Hajj, N. E., Yang, H. H., Hu, Y., Sticht, C., Nanda, I., Belle, S., Rueschoff, J., Lee, M. P., et al. (2019) · Genes Chromosomes and Cancer · doi:10.1002/gcc.22787 · Cited by 21
Kim, S. H., Kwon, W., & Joung, J. Y. (2020) · The World Journal of Men s Health · doi:10.5534/wjmh.190135 · Cited by 21
Posttranslational modifications as therapeutic targets for intestinal disorders
Choo, J., Heo, G., Pothoulakis, C., & Im, E. (2021) · Pharmacological Research · doi:10.1016/j.phrs.2020.105412 · Cited by 21
Matsunaga, T., Saito, H., Miyauchi, W., Shishido, Y., Miyatani, K., Morimoto, M., Murakami, Y., Hanaki, T., Kihara, K., Yamamoto, M., et al. (2021) · BMC Cancer · doi:10.1186/s12885-021-08953-8 · Cited by 22
Zhang, H., Ding, Y., Zeng, Q., Wang, D., Liu, G., Hussain, Z. S., Xiao, B., Liu, W., & Deng, T. (2022) · American Journal of Physiology-Gastrointestinal and Liver Physiology · doi:10.1152/ajpgi.00256.2021 · Cited by 21
Sheng, Y., Davies, J. M., Wang, R., Wong, K. Y., Giri, R., Yang, Y., Begun, J., Florin, T. H., Hasnain, S. Z., & McGuckin, M. A. (2022) · Cellular and Molecular Gastroenterology and Hepatology · doi:10.1016/j.jcmgh.2022.06.010 · Cited by 21
Gawiński, C., Hołdakowska, A., & Wyrwicz, L. S. (2022) · Current Oncology · doi:10.3390/curroncol30010043 · Cited by 21
Shimomura, K., Hattori, N., Iida, N., Muranaka, Y., Sato, K., Shiraishi, Y., Arai, Y., Hama, N., Shibata, T., Narushima, D., et al. (2023) · Nature Communications · doi:10.1038/s41467-023-42228-z · Cited by 21
Ji, B., Zou, H., Xu, L., Xie, X., & Peng, S. (2024) · Briefings in Bioinformatics · doi:10.1093/bib/bbae167 · Cited by 21
Resler, A. J., Makar, K. W., Heath, L., Whitton, J. A., Potter, J. D., Poole, E. M., Habermann, N., Scherer, D., Duggan, D. J., Wang, H., et al. (2014) · Carcinogenesis · doi:10.1093/carcin/bgu119 · Cited by 21
Dodov, M. G., Steffansen, B., Crcarevska, M. S., Geškovski, N., Dimchevska, S., Kuzmanovska, S., & Goračinova, K. (2013) · Journal of Microencapsulation · doi:10.3109/02652048.2013.770099 · Cited by 21
Role of Matrix Metalloproteinases in Inflammation/Colitis-Associated Colon Cancer
Walter, L. (2013) · ImmunoGastroenterology · doi:10.7178/ig.29 · Cited by 21
Ismail, S., Rao, K., & Bhaskar, M. (2016) · International Journal of Research in Medical Sciences · doi:10.18203/2320-6012.ijrms20161989 · Cited by 21
Anticancer Efficacy of Some Plant Phenolics - A Recent Scenario
Chander, M. (2018) · International Journal of Current Microbiology and Applied Sciences · doi:10.20546/ijcmas.2018.710.200 · Cited by 21
Circular RNA expression alterations in colon tissues of Crohn's disease patients
Qiao, Y., Cai, C., Shen, J., Zheng, Q., & Ran, Z. H. (2019) · Molecular Medicine Reports · doi:10.3892/mmr.2019.10070 · Cited by 22
GOLM1 Drives Colorectal Cancer Metastasis by Regulating Myeloid-derived Suppressor Cells
Dang, Y., Yu, J., Zhao, S., Jin, L. G., Cao, X., & Wang, Q. (2021) · Journal of Cancer · doi:10.7150/jca.61567 · Cited by 20
Liu, J., Hao, W., Hsu, Y.-P., Sung, L., Kao, P., Lin, C., Wu, A. T. H., Yuan, K. S., & Wu, S. (2016) · Oncotarget · doi:10.18632/oncotarget.11263 · Cited by 25
Zhao, J., Wu, R. T., Wei, P., Ma, Z., Pei, H., Hu, J., Wen, F., & Wan, L. (2023) · Journal of Ethnopharmacology · doi:10.1016/j.jep.2023.116293 · Cited by 20
Tanjak, P., Chaiboonchoe, A., Suwatthanarak, T., Thanormjit, K., Acharayothin, O., Chanthercrob, J., Parakonthun, T., Methasate, A., Fischer, J. M., Wong, M. H., et al. (2024) · Clinical and Experimental Medicine · doi:10.1007/s10238-024-01515-9 · Cited by 23
Peroxisome proliferators-activated receptor gamma polymorphisms and colorectal cancer risk
Liang, X., Fan, X., Tan, K., Zhang, L., Jian, L., & Yu, L. (2018) · Journal of Cancer Research and Therapeutics · doi:10.4103/0973-1482.235346 · Cited by 20
Berberine Administration in Treatment of Colitis: A Review
Ashrafizadeh, M., Najafi, M., Mohammadinejad, R., Farkhondeh, T., & Samarghandian, S. (2020) · Current Drug Targets · doi:10.2174/1389450121666200621193758 · Cited by 20
Hoshino, S., Takeuchi, M., Kawakubo, H., Matsuda, S., Mayanagi, S., Irino, T., Fukuda, K., Nakamura, R., Wada, N., & Kitagawa, Y. (2021) · Annals of Surgical Oncology · doi:10.1245/s10434-021-09637-0 · Cited by 20
Clinicopathological significance of neutrophil-rich colorectal carcinoma
Rottmann, B. G., Patel, N. J., Ahmed, M. S., Deng, Y., Ciarleglio, M. M., Vyas, M., Jain, D., & Zhang, X. (2021) · Journal of Clinical Pathology · doi:10.1136/jclinpath-2021-207702 · Cited by 20
A New Story of the Three Magi: Scaffolding Proteins and lncRNA Suppressors of Cancer
Kotelevets, L., & Chastre, E. (2021) · Cancers · doi:10.3390/cancers13174264 · Cited by 21
Myeloid-derived suppressor cells in colorectal cancer: prognostic biomarkers and therapeutic targets
Al-Mterin, M. A., & Elkord, E. (2022) · Exploration of Targeted Anti-tumor Therapy · doi:10.37349/etat.2022.00097 · Cited by 21
Protein stabilization of ITF2 by NF-κB prevents colitis-associated cancer development
Lee, M., KIM, Y., Lim, S., Shin, S.-H., Kim, I., Kim, J., Choi, M., Kim, J. H., Koh, S., Park, J., et al. (2023) · Nature Communications · doi:10.1038/s41467-023-38080-w · Cited by 20
Shimizu, M., Kochi, T., Shirakami, Y., Genovese, S., Epifano, F., Fiorito, S., Mōri, T., Tanaka, T., & Moriwaki, H. (2014) · International Journal of Cancer · doi:10.1002/ijc.28718 · Cited by 20
Can we change our microbiome to prevent colorectal cancer development?
Manzat-Saplacan, R. M., Mircea, P. A., Bălăcescu, L., Chira, R. I., Berindan‐Neagoe, I., & Bălăcescu, O. (2015) · Acta Oncologica · doi:10.3109/0284186x.2015.1054949 · Cited by 20
Xiu, D., Liu, L., Qiao, F., Yang, H., Cui, L., & Liu, G. (2016) · Gastroenterology Research and Practice · doi:10.1155/2016/3521453 · Cited by 20
Feedback mechanisms between M2 macrophages and Th17 cells in colorectal cancer patients
Mao, H., Pan, F., Guo, H., Bu, F., Xin, T., Chen, S., & Guo, Y. (2016) · Tumor Biology · doi:10.1007/s13277-016-5085-z · Cited by 20
Mao, H., Pan, F., Wu, Z., Wang, Z., Zhou, Y., Zhang, P., Gou, M., & Dai, G. (2017) · DNA and Cell Biology · doi:10.1089/dna.2017.3814 · Cited by 20
Tao, Y., Liu, Z., Hou, Y., Wang, S., Liu, S., Jiang, Y., Tan, D., Ge, Q., Li, C., Hu, Y., et al. (2018) · Oncogene · doi:10.1038/s41388-018-0363-4 · Cited by 20
A mouse model of the Δ133p53 isoform: roles in cancer progression and inflammation
Kazantseva, M., Mehta, S. Y., Eiholzer, R. A., Hung, N. A., Wiles, A. K., Slatter, T. L., & Braithwaite, A. W. (2018) · Mammalian Genome · doi:10.1007/s00335-018-9758-3 · Cited by 21
Yuan, G., Chen, T., Zhang, H., Cao, Q., Qiu, Y., Que, B., Peng, S., Chen, M., & Ji, W. (2018) · Molecular Carcinogenesis · doi:10.1002/mc.22900 · Cited by 20
Li, X., An, B., Zhao, Q., Qi, J., Wang, W., Zhang, D., Li, Z., & Qin, C. (2018) · Cancer Management and Research · doi:10.2147/cmar.s161094 · Cited by 20
The rate and importance of Clostridium difficile in colorectal cancer patients.
Jahani-Sherafat, S., Azimirad, M., Alebouyeh, M., Amoli, H. A., Hosseini, P., Ghasemian-Safaei, H., & Moghim, S. (2019) · Gastroenterology and hepatology from bed to bench. · Cited by 20
Darband, S. G., Saboory, E., Sadighparvar, S., Kaviani, M., Mobaraki, K., Jabbari, N., & Majidinia, M. (2019) · Canadian Journal of Physiology and Pharmacology · doi:10.1139/cjpp-2019-0329 · Cited by 20
Oh, N. S., Joung, J. Y., Lee, J. Y., Kim, Y. J., Kim, Y., & Kim, S. H. (2020) · Journal of Dairy Science · doi:10.3168/jds.2019-17411 · Cited by 20
Metadata
- Authors
- Terzić, J., Grivennikov, S., Karin, E., & Karin, M.
- Affiliations
- University of California San Diego (US)
- Tel Aviv Sourasky Medical Center (IL)
- Corresponding author
- Karin, Michael
- Venue
- Gastroenterology
- Publisher
- Elsevier BV
- Published
- 2010-05
- Volume
- 138
- Issue
- 6
- Pages
- 2101-2114.e5
- ISSN
- 0016-5085 (ISSN-L)
- OpenAlex
- W2085852125
- Cited by
- 1,974
- References
- 247
- Citations by year
- 2026: 41 · 2025: 80 · 2024: 106 · 2023: 140 · 2022: 147 · 2021: 192 · 2020: 159 · 2019: 139 · 2018: 144 · 2017: 145 · 2016: 136 · 2015: 127 · 2014: 112 · 2013: 119 · 2012: 86
- FWCI
- 10.78
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- Gastroenterology (publishedVersion)
- PubMed (publishedVersion)
- Funders
- National Institutes of Health
- Crohn's and Colitis Foundation of America (1762)
- American Association for Cancer Research
- American Cancer Society
- Topics
- Health Sciences › Medicine › Pharmacology (medical) › Inflammatory mediators and NSAID effects
- Life Sciences › Immunology and Microbiology › Immunology › Immune cells in cancer
- Health Sciences › Medicine › Gastroenterology › Inflammatory Bowel Disease
- Keywords
- inflammation, colon cancer, colorectal cancer, inflammatory bowel disease, colitis-associated colorectal cancer, carcinogenesis, immune cells, cytokines, cancer prevention, cancer therapy, metastasis
- MeSH terms
- Animals, Anti-Inflammatory Agents, Cell Transformation, Neoplastic, Colon, Colonic Neoplasms, Humans, Neoplasm Invasiveness, Risk Factors, Colorectal Neoplasms, Inflammatory Bowel Diseases, Signal Transduction, Gene Expression Regulation, Neoplastic, Cytokines, Anticarcinogenic Agents, Risk Assessment, Inflammation Mediators, Genetic Predisposition to Disease
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review