Inflammation and Colon Cancer

A genetic model for colorectal tumorigenesis

Fearon, E. R., & Vogelstein, B. (1990) · Cell · doi:10.1016/0092-8674(90)90186-i · Cited by 12,132

Cancer-related inflammation

Mantovani, A., Allavena, P., Sica, A., & Balkwill, F. (2008) · Nature · doi:10.1038/nature07205 · Cited by 11,399

Immunity, Inflammation, and Cancer

Grivennikov, S. I., Greten, F. R., & Karin, M. (2010) · Cell · doi:10.1016/j.cell.2010.01.025 · Cited by 10,755

The basics of epithelial-mesenchymal transition

Kalluri, R., & Weinberg, R. A. (2009) · Journal of Clinical Investigation · doi:10.1172/jci39104 · Cited by 10,196

Cancer Statistics, 2008

Jemal, A., Siegel, R. L., Ward, E., Hao, Y., Xu, J., Murray, T., & Thun, M. J. (2008) · CA A Cancer Journal for Clinicians · doi:10.3322/ca.2007.0010 · Cited by 10,184

Reciprocal developmental pathways for the generation of pathogenic effector TH17 and regulatory T cells

Bettelli, E., Carrier, Y., Gao, W., Korn, T., Strom, T. B., Oukka, M., Weiner, H. L., & Kuchroo, V. K. (2006) · Nature · doi:10.1038/nature04753 · Cited by 6,992

Myeloid-derived-suppressor cells as regulators of the immune system

Gabrilovich, D. I., & Nagaraj, S. (2009) · Nature Reviews Immunology · doi:10.1038/nri2506 · Cited by 6,753

Type, Density, and Location of Immune Cells Within Human Colorectal Tumors Predict Clinical Outcome

Galon, J., Costes, A., Sanchez-Cabo, F., Kirilovsky, A., Mlecnik, B., Lagorce-Pagès, C., Tosolini, M., Camus, M., Berger, A., Wind, P., et al. (2006) · Science · doi:10.1126/science.1129139 · Cited by 6,516

Metagenomic Analysis of the Human Distal Gut Microbiome

Gill, S. R., Pop, M., DeBoy, R. T., Eckburg, P. B., Turnbaugh, P. J., Samuel, B. S., Gordon, J. I., Relman, D. A., Fraser-Liggett, C. M., & Nelson, K. E. (2006) · Science · doi:10.1126/science.1124234 · Cited by 4,699

STATs in cancer inflammation and immunity: a leading role for STAT3

Yu, H., Pardoll, D., & Jove, R. (2009) · Nature reviews. Cancer · doi:10.1038/nrc2734 · Cited by 4,383

Mitogen‐activated protein kinase‐activated protein kinase‐2 (MK2) and its role in cell survival, inflammatory signaling, and migration in promoting cancer

Morgan, D., Berggren, K. L., Spiess, C., Smith, H. M., Tejwani, A., Weir, S. J., Lominska, C. E., Thomas, S. M., & Gan, G. N. (2021) · Molecular Carcinogenesis · doi:10.1002/mc.23348 · Cited by 42

Black chokeberry ( Aronia melanocarpa L.) polyphenols attenuate obesity-induced colonic inflammation by regulating gut microbiota and the TLR4/NF-κB signaling pathway in high fat diet-fed rats

Zhu, Y., Cai, P.-J., Dai, H.-C., Xiao, Y., Jia, C., & Sun, A. (2023) · Food & Function · doi:10.1039/d3fo02177g · Cited by 44

Curcumin and its anti‐colorectal cancer potential: From mechanisms of action to autophagy

Brockmueller, A., de Porras, V. R., & Shakibaei, M. (2024) · Phytotherapy Research · doi:10.1002/ptr.8220 · Cited by 45

Serum Interleukin-6, Insulin, and HOMA-IR in Male Individuals with Colorectal Adenoma

Sasaki, Y., Takeda, H., SATO, T. A., Orii, T., Nishise, S., Nagino, K., Iwano, D., Yaoita, T., Yoshizawa, K., Saito, H., et al. (2011) · Clinical Cancer Research · doi:10.1158/1078-0432.ccr-11-0896 · Cited by 42

3-Aroylmethylene-2,3,6,7-tetrahydro-1H-pyrazino[2,1-a]isoquinolin-4(11bH)-ones as Potent Nrf2/ARE Inducers in Human Cancer Cells and AOM-DSS Treated Mice

Xi, M., Jia, J.-M., Sun, H.-P., Sun, Z., Jiang, J., Wang, Y., Zhang, M., Zhu, J., Xu, L., Jiang, Z., et al. (2013) · Journal of Medicinal Chemistry · doi:10.1021/jm400944k · Cited by 42

Local and systemic Th17 immune response associated with advanced stage colon cancer

Sharp, S. P., Avram, D., Stain, S. C., & Lee, E. C. (2016) · Journal of Surgical Research · doi:10.1016/j.jss.2016.09.038 · Cited by 44

The receptor tyrosine kinase AXL promotes migration and invasion in colorectal cancer

Uribe, D. J., Mandell, E. K., Watson, A., Martinez, J. D., Leighton, J. A., Ghosh, S., & Rothlin, C. V. (2017) · PLoS ONE · doi:10.1371/journal.pone.0179979 · Cited by 42

Circulating fibrinogen to pre‐albumin ratio is a promising biomarker for diagnosis of colorectal cancer

Sun, F., Tan, Y., Gao, Q., Li, S., Zhang, J., Chen, Q., Jiang, Y., Zhang, L., Ying, H., & Wang, X. (2018) · Journal of Clinical Laboratory Analysis · doi:10.1002/jcla.22635 · Cited by 40

Interleukin-33 and ST2 Signaling in Tumor Microenvironment

Hong, J., Kim, S., & Lin, P. C. (2018) · Journal of Interferon & Cytokine Research · doi:10.1089/jir.2018.0044 · Cited by 43

Suppression of interferon gene expression overcomes resistance to MEK inhibition in KRAS-mutant colorectal cancer

Wagner, S., Vlachogiannis, G., Brandon, A. D. H., Valenti, M. R., Box, G., Jenkins, L., Mancusi, C., Self, A. J., Manodoro, F., Assiotis, I., et al. (2018) · Oncogene · doi:10.1038/s41388-018-0554-z · Cited by 43

Inflammation-induced JMJD2D promotes colitis recovery and colon tumorigenesis by activating Hedgehog signaling

Zhuo, M., Chen, W., Shang, S., Guo, P., Peng, K., Li, M., Mo, P., Zhang, Y., Qiu, X., Li, W., et al. (2020) · Oncogene · doi:10.1038/s41388-020-1219-2 · Cited by 42

Targeted Delivery of CXCL9 and OX40L by Mesenchymal Stem Cells Elicits Potent Antitumor Immunity

Yin, P., Gui, L., Wang, C., Yan, J., Liu, M., Ji, L., Wang, Y., Ma, B., & Gao, W. (2020) · Molecular Therapy · doi:10.1016/j.ymthe.2020.08.005 · Cited by 44

Glycyrrhizin Attenuates Carcinogenesis by Inhibiting the Inflammatory Response in a Murine Model of Colorectal Cancer

Wang, G., Hiramoto, K., Ma, N., Yoshikawa, N., Ohnishi, S., Murata, M., & Kawanishi, S. (2021) · International Journal of Molecular Sciences · doi:10.3390/ijms22052609 · Cited by 47

Dual role of heme iron in cancer; promotor of carcinogenesis and an inducer of tumour suppression

Gamage, S. M. K., Lee, K. T., Dissabandara, L., Lam, A. K.-Y., & Gopalan, V. (2021) · Experimental and Molecular Pathology · doi:10.1016/j.yexmp.2021.104642 · Cited by 44

Cystine reduces tight junction permeability and intestinal inflammation induced by oxidative stress in Caco-2 cells

Hasegawa, T., Mizugaki, A., Inoue, Y., Kato, H., & Murakami, H. (2021) · Amino Acids · doi:10.1007/s00726-021-03001-y · Cited by 43

Hyaluronic a cid–doxorubicin nanoparticles for targeted treatment of colorectal cancer

Pan, D. C., Krishnan, V., Salinas, A. K., Kim, J., Sun, T., Ravid, S., Peng, K., Wu, D., Nurunnabi, M., Nelson, J. A., et al. (2021) · Bioengineering & Translational Medicine · doi:10.1002/btm2.10166 · Cited by 42

The multifaceted role of extracellular vesicles (EVs) in colorectal cancer: metastasis, immune suppression, therapy resistance, and autophagy crosstalk

Rahmati, S., Moeinafshar, A., & Rezaei, N. (2024) · Journal of Translational Medicine · doi:10.1186/s12967-024-05267-8 · Cited by 47

De-coding the complex role of microbial metabolites in cancer

Escriva, P. P., Bernardino, C. C. T., & Letellier, E. (2025) · Cell Reports · doi:10.1016/j.celrep.2025.115358 · Cited by 48

Slit2/Robo1 signaling promotes intestinal tumorigenesis through Src-mediated activation of the Wnt/β-catenin pathway

Zhang, Q., Zhou, D., Lei, Y., Li, Z., Chen, S., Gou, H., Gu, Q., He, X., Lan, T., Qi, C., et al. (2014) · Oncotarget · doi:10.18632/oncotarget.3060 · Cited by 41

A Prospective Follow-up Study of the Relationship between C-Reactive Protein and Human Cancer Risk in the Chinese Kailuan Female Cohort

Wang, G., Li, N., Chang, S., Bassig, B. A., Guo, L., Ren, J., Su, K., Li, F., Chen, S., Wu, S., et al. (2014) · Cancer Epidemiology Biomarkers & Prevention · doi:10.1158/1055-9965.epi-14-1112 · Cited by 41

Regulatory miRNAs in Colorectal Carcinogenesis and Metastasis

Guo, Y., Bao, Y., & Yang, W. (2017) · International Journal of Molecular Sciences · doi:10.3390/ijms18040890 · Cited by 41

Association between dietary inflammatory index, and cause-specific mortality in the MONICA/KORA Augsburg Cohort Study

Shivappa, N., Schneider, A. L. C., Hébert, J. R., Köenig, W., Peters, A., & Thorand, B. (2017) · European Journal of Public Health · doi:10.1093/eurpub/ckx060 · Cited by 41

Mechanisms coupling thrombin to metastasis and tumorigenesis

Remiker, A. S., & Palumbo, J. S. (2018) · Thrombosis Research · doi:10.1016/j.thromres.2017.12.020 · Cited by 41

Mesenchymal MAPKAPK2/HSP27 drives intestinal carcinogenesis

Henriques, A. R., Koliaraki, V., & Kollias, G. A. (2018) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1805683115 · Cited by 41

Combined Low Densities of FoxP3+ and CD3+ Tumor-Infiltrating Lymphocytes Identify Stage II Colorectal Cancer at High Risk of Progression

Cavalleri, T., Bianchi, P. P., Basso, G., Celesti, G., Grizzi, F., Bossi, P., Greco, L., Pitrone, C., Valtorta, E., Mauri, G., et al. (2019) · Cancer Immunology Research · doi:10.1158/2326-6066.cir-18-0661 · Cited by 41

Visualization of epithelial-mesenchymal transition in an inflammatory microenvironment–colorectal cancer network

Ieda, T., Tazawa, H., Okabayashi, H., Yano, S., Shigeyasu, K., Kuroda, S., Ohara, T., Noma, K., Kishimoto, H., Nishizaki, M., et al. (2019) · Scientific Reports · doi:10.1038/s41598-019-52816-z · Cited by 40

Genome-wide CRISPR screen identifies LGALS2 as an oxidative stress-responsive gene with an inhibitory function on colon tumor growth

Li, H., Zhao, L., Lau, Y. S., Zhang, C., & Han, R. (2020) · Oncogene · doi:10.1038/s41388-020-01523-5 · Cited by 41

Overcoming cancer risk in inflammatory bowel disease: new insights into preventive strategies and pathogenesis mechanisms including interactions of immune cells, cancer signaling pathways, and gut microbiota

Zhang, H., Shi, Y., Lin, C., He, C., Wang, S., Li, Q., Sun, Y. P., & Li, M. (2024) · Frontiers in Immunology · doi:10.3389/fimmu.2023.1338918 · Cited by 40

Ensemble of Gene Signatures Identifies Novel Biomarkers in Colorectal Cancer Activated through PPARγ and TNFα Signaling

Pagnotta, S. M., Laudanna, C., Pancione, M., Sabatino, L., Votino, C., Remo, A., Cerulo, L., Zoppoli, P., Manfrin, E., Colantuoni, V., et al. (2013) · PLoS ONE · doi:10.1371/journal.pone.0072638 · Cited by 40

Significant association between IL23R and IL17F polymorphisms and clinical features of colorectal cancer

Omrane, I., Baroudi, O., Bougatef, K., Mézlini, A., Abidi, A., Medimegh, I., Stambouli, N., Ayari, H., Kourda, N., Uhrhammer, N. A., et al. (2014) · Immunology Letters · doi:10.1016/j.imlet.2014.01.002 · Cited by 40

Prognostic significance of the preoperative lymphocyte-to-monocyte ratio in patients with colorectal cancer

Shibutani, M., Maeda, K., Nagahara, H., Iseki, Y., Ikeya, T., & Hirakawa, K. (2016) · Oncology Letters · doi:10.3892/ol.2016.5487 · Cited by 40

Long noncoding RNA HOTAIR silencing inhibits invasion and proliferation of human colon cancer LoVo cells via regulating IGF2BP2

Wu, X., Lu, R., Wang, L., Wang, Y., Dai, Y., Wang, C., Yang, Y., Guo, F., Xue, J., & Yang, D. (2019) · Journal of Cellular Biochemistry · doi:10.1002/jcb.27079 · Cited by 40

Inflammation‐dependent overexpression of c‐Myc enhances CRL4DCAF4 E3 ligase activity and promotes ubiquitination of ST7 in colitis‐associated cancer

Liu, H., Lu, W., He, H., Wu, J., Zhang, C., Gong, H., & Yang, C. (2019) · The Journal of Pathology · doi:10.1002/path.5273 · Cited by 40

Bufalin, a Traditional Chinese Medicine Compound, Prevents Tumor Formation in Two Murine Models of Colorectal Cancer

Sun, X. Y., Ng, T. T. H., Sham, K. W. Y., Zhang, L., Chan, M. T. V., Wu, W. K. K., & Cheng, C. H. K. (2019) · Cancer Prevention Research · doi:10.1158/1940-6207.capr-19-0134 · Cited by 40

PAR2 deficiency enhances myeloid cell-mediated immunosuppression and promotes colitis-associated tumorigenesis

Ke, Z., Wang, C., Wu, T., Wang, W., Yang, Y., & Dai, Y. (2019) · Cancer Letters · doi:10.1016/j.canlet.2019.11.015 · Cited by 40

Significance of the 7th postoperative day neutrophil-to-lymphocyte ratio in colorectal cancer

Hayama, T., Hashiguchi, Y., Okada, Y., Ono, K., Nemoto, K., Shimada, R., Ozawa, T., Toyoda, T., Tsuchiya, T., Iinuma, H., et al. (2019) · International Journal of Colorectal Disease · doi:10.1007/s00384-019-03463-3 · Cited by 40

Influence of Iron on the Gut Microbiota in Colorectal Cancer

Phipps, O., Al-Hassi, H. O., Quraishi, M. N., Kumar, A., & Brookes, M. (2020) · Nutrients · doi:10.3390/nu12092512 · Cited by 41

The anti-tumor effects of CT-26 derived exosomes enriched by MicroRNA-34a on murine model of colorectal cancer

Hosseini, M. S., Baghaei, K., Hajivalili, M., Zali, M. R., Ebtekar, M., & Amani, D. (2021) · Life Sciences · doi:10.1016/j.lfs.2021.120234 · Cited by 40

C-Reactive Protein, Lipid-soluble Micronutrients, and Survival in Colorectal Cancer Patients

Cooney, R. V., Chai, W., Franke, A. A., Wilkens, L. R., Kolonel, L. N., & Marchand, L. L. (2013) · Cancer Epidemiology Biomarkers & Prevention · doi:10.1158/1055-9965.epi-13-0199 · Cited by 40

High Concentrations of Genistein Decrease Cell Viability Depending on Oxidative Stress and Inflammation in Colon Cancer Cell Lines

Alorda-Clara, M., Torrens‐Mas, M., Morla-Barcelo, P. M., Roca, P., Sastre‐Serra, J., Pons, D. G., & Oliver, J. (2022) · International Journal of Molecular Sciences · doi:10.3390/ijms23147526 · Cited by 39

Influence of chronic moderate sleep restriction and exercise on inflammation and carcinogenesis in mice

Zielinski, M. R., Davis, J. M., Fadel, J. R., & Youngstedt, S. D. (2012) · Brain Behavior and Immunity · doi:10.1016/j.bbi.2012.03.002 · Cited by 39

The Laminin Response in Inflammatory Bowel Disease: Protection or Malignancy?

Spenlé, C., Lefèbvre, O., Lacroute, J., Méchine‐Neuville, A., Barreau, F., Blottière, H. M., Duclos, B., Arnold, C., Hussenet, T., Hemmerlé, J., et al. (2014) · PLoS ONE · doi:10.1371/journal.pone.0111336 · Cited by 39

Thrombin Drives Tumorigenesis in Colitis-Associated Colon Cancer

Turpin, B. K., Miller, W., Rosenfeldt, L. A., Kombrinck, K. W., Flick, M. J., Steinbrecher, K. A., Harmel-Laws, E., Mullins, E. S., Shaw, M. A., Witte, D. P., et al. (2014) · Cancer Research · doi:10.1158/0008-5472.can-13-3276 · Cited by 39

Colon Cancer Chemoprevention by Sage Tea Drinking: Decreased DNA Damage and Cell Proliferation

Pedro, D. F. N., Ramos, A. A., Lima, C. F., Baltazar, F., & Pereira‐Wilson, C. (2015) · Phytotherapy Research · doi:10.1002/ptr.5531 · Cited by 40

The eicosanoids leukotriene D4 and prostaglandin E2 promote the tumorigenicity of colon cancer-initiating cells in a xenograft mouse model

Bellamkonda, K., Chandrashekar, N., Osman, J., Selvanesan, B. C., Savari, S., & Sjölander, A. (2016) · BMC Cancer · doi:10.1186/s12885-016-2466-z · Cited by 39

Aggregates of octenylsuccinate oat β-glucan as novel capsules to stabilize curcumin over food processing, storage and digestive fluids and to enhance its bioavailability

Liu, J., Lei, L., Ye, F., Zhou, Y., Younis, H. G. R., & Zhao, G. (2017) · Food & Function · doi:10.1039/c7fo01569k · Cited by 40

Colorectal Cancer Is Associated with a Deficiency of Lipoxin A 4 , an Endogenous Anti-inflammatory Mediator

Liu, H., Zeng, J., Huang, W., Xu, Q., Ye, D., Sun, R., & Zhang, D. (2019) · Journal of Cancer · doi:10.7150/jca.32456 · Cited by 39

Systemic Interleukins’ Profile in Early and Advanced Colorectal Cancer

Czajka‐Francuz, P., Cisoń-Jurek, S., Czajka, A., Kozaczka, M., Wojnar, J., Chudek, J. T., & Francuz, T. (2021) · International Journal of Molecular Sciences · doi:10.3390/ijms23010124 · Cited by 42

PAF receptor antagonist Ginkgolide B inhibits tumourigenesis and angiogenesis in colitis-associated cancer.

Sun, L., He, Z., Ke, J., Li, S., Wu, X., Lian, L., He, X., He, X., Hu, J., Zou, Y., et al. (2015) · Europe PMC (PubMed Central) · Cited by 39

Interleukin-21 in cancer immunotherapy

Stolfi, C., Pallone, F., MacDonald, T. T., & Monteleone, G. (2012) · OncoImmunology · doi:10.4161/onci.19122 · Cited by 39

Signaling controversy and future therapeutical perspectives of targeting sphingolipid network in cancer immune editing and resistance to tumor necrosis factor-α immunotherapy

Sukocheva, O. A., Неганова, М. Е., Aleksandrova, Y. R., Burcher, J. T., Chugunova, E., Fan, R., Tse, E., Sethi, G., Bishayee, A., & Liu, J. (2024) · Cell Communication and Signaling · doi:10.1186/s12964-024-01626-6 · Cited by 42

Rab27A mediated by NF-κB promotes the stemness of colon cancer cells via up-regulation of cytokine secretion

Feng, F., Jiang, Y., Lu, H., Lu, X., Wang, S., Wang, L., Wei, M., Lu, W., Du, Z., Ye, Z., et al. (2016) · Oncotarget · doi:10.18632/oncotarget.11454 · Cited by 38

Elevated Platelet to Lymphocyte Ratio Is Associated with Poor Survival Outcomes in Patients with Colorectal Cancer

Gu, X., Gao, X., Qin, S., Li, X., Qi, X., Ma, M., Yu, H., Sun, S., Zhou, D., Wang, W., et al. (2016) · PLoS ONE · doi:10.1371/journal.pone.0163523 · Cited by 38

Peritoneal carcinomatosis of colorectal cancer is characterized by structural and functional reorganization of the tumor microenvironment inducing senescence and proliferation arrest in cancer cells

Seebauer, C. T., Brunner, S. M., Glockzin, G., Piso, P., Ruemmele, P., Schlitt, H. J., Geissler, E. K., Fichtner‐Feigl, S., & Kesselring, R. (2016) · OncoImmunology · doi:10.1080/2162402x.2016.1242543 · Cited by 39

Markers of systemic inflammation and colorectal adenoma risk: Meta-analysis of observational studies

Godos, J., Biondi, A., Galvano, F., Basile, F., Sciacca, S., Giovannucci, E. L., & Grosso, G. (2017) · World Journal of Gastroenterology · doi:10.3748/wjg.v23.i10.1909 · Cited by 38

Platelets contribute to the initiation of colitis‐associated cancer by promoting immunosuppression

Servais, L., Wéra, O., Epoh, J. D., Delierneux, C., Bouznad, N., Rahmouni, S., Mazzucchelli, G., Baiwir, D., Delvenne, P., Lancellotti, P., et al. (2018) · Journal of Thrombosis and Haemostasis · doi:10.1111/jth.13959 · Cited by 38

miR-34a is a microRNA safeguard for Citrobacter-induced inflammatory colon oncogenesis

Wang, L., Wang, E., Wang, Y., Mines, R. C., Xiang, K., Sun, Z., Zhou, G., Chen, K., Rakhilin, N., Chao, S., et al. (2018) · eLife · doi:10.7554/elife.39479 · Cited by 39

Schisandrin B prevents ulcerative colitis and colitis-associated-cancer by activating focal adhesion kinase and influence on gut microbiota in an in vivo and in vitro model

Li, J., Lu, Y., Wang, D., Quan, F., Chen, X., Sun, R., Zhao, S., Yang, Z., Tao, W., Ding, D., et al. (2019) · European Journal of Pharmacology · doi:10.1016/j.ejphar.2019.03.059 · Cited by 39

TRIM31 regulates chronic inflammation via NF-κB signal pathway to promote invasion and metastasis in colorectal cancer.

Wang, H., Lu, Y., Gong, Y., & Zhang, B. (2018) · Europe PMC (PubMed Central) · Cited by 39

The chemopreventive effect of 5-demethylnobiletin, a unique citrus flavonoid, on colitis-driven colorectal carcinogenesis in mice is associated with its colonic metabolites

Song, M., Lan, Y., Wu, X., Han, Y., Wang, M., Zheng, J., Li, Z., Li, F., Zhou, J., Xiao, J., et al. (2020) · Food & Function · doi:10.1039/d0fo00616e · Cited by 38

The thrombin–inflammation axis in cancer progression

Cantrell, R., & Palumbo, J. S. (2020) · Thrombosis Research · doi:10.1016/s0049-3848(20)30408-4 · Cited by 38

All are Equal, Some are More Equal: Targeting IL 12 and 23 in IBD – A Clinical Perspective

Jefremow, A., & Neurath, M. F. (2020) · ImmunoTargets and Therapy · doi:10.2147/itt.s282466 · Cited by 38

Promising Potential of Crude Polysaccharides from Sparassis crispa against Colon Cancer: An In Vitro Study

Nowacka-Jechalke, N., Nowak, R., Lemieszek, M. K., Rzeski, W., Gawlik‐Dziki, U., Szpakowska, N., & Kaczyński, Z. (2021) · Nutrients · doi:10.3390/nu13010161 · Cited by 38

Antiproliferative Activity on Human Colon Adenocarcinoma Cells and In Vitro Antioxidant Effect of Anthocyanin-Rich Extracts from Peels of Species of the Myrtaceae Family

Frauches, N. S., Montenegro, J., Amaral, T., de Abreu, J. P., Pascoal, G. D. F. L., Junior, J., Borguini, R. G., Santiago, M. C. P. D. A., Pacheco, S., Nakajima, V. M., et al. (2021) · Molecules · doi:10.3390/molecules26030564 · Cited by 38

Stem Cell Impairment at the Host-Microbiota Interface in Colorectal Cancer

Marzano, M., Fosso, B., Piancone, E., Defazio, G., Pesole, G., & Robertis, M. D. (2021) · Cancers · doi:10.3390/cancers13050996 · Cited by 40

Efferocytosis in multisystem diseases (Review)

Zhang, Y., Wang, Y., Ding, J., & Liu, P. (2021) · Molecular Medicine Reports · doi:10.3892/mmr.2021.12529 · Cited by 38

Wu-Mei-Wan Ameliorates Murine Ulcerative Colitis by Regulating Macrophage Polarization

Yan, S., Wei, H., Jia, R., Zhen, M., Bao, S., Wang, W., Liu, F., & Jingtao, L. (2022) · Frontiers in Pharmacology · doi:10.3389/fphar.2022.859167 · Cited by 40

Emerging role for thymic stromal lymphopoietin–responsive regulatory T cells in colorectal cancer progression in humans and mice

Obata‐Ninomiya, K., Carrion, S. D. J., Hu, A. K., & Ziegler, S. F. (2022) · Science Translational Medicine · doi:10.1126/scitranslmed.abl6960 · Cited by 37

Designing multi-epitope vaccine against important colorectal cancer (CRC) associated pathogens based on immunoinformatics approach

Motamedi, H., Ari, M. M., Shahlaei, M., Moradi, S., Farhadikia, P., Alvandi, A., & Abiri, R. (2023) · BMC Bioinformatics · doi:10.1186/s12859-023-05197-0 · Cited by 37

CD93 gene polymorphism is associated with disseminated colorectal cancer

Olsen, R. S., Lindh, M., Vorkapić, E., Andersson, R. E., Zar, N., Löfgren, S., Dimberg, J., Matussek, A., & Wågsäter, D. (2015) · International Journal of Colorectal Disease · doi:10.1007/s00384-015-2247-1 · Cited by 37

Plasma Inflammatory Markers and Risk of Advanced Colorectal Adenoma in Women

Song, M., Mehta, R. S., Wu, K., Fuchs, C. S., Ogino, S., Giovannucci, E. L., & Chan, A. T. (2015) · Cancer Prevention Research · doi:10.1158/1940-6207.capr-15-0307 · Cited by 37

A Role for the Epidermal Growth Factor Receptor Signaling in Development of Intestinal Serrated Polyps in Mice and Humans

Bongers, G., Muniz, L. R., Pacer, M. E., Iuga, A. C., Thirunarayanan, N., Slinger, E., Smit, M. J., Reddy, E. P., Mayer, L., Furtado, G. C., et al. (2012) · Gastroenterology · doi:10.1053/j.gastro.2012.05.034 · Cited by 37

Treg subsets in inflammatory bowel disease and colorectal carcinoma: Characteristics, role, and therapeutic targets

van Herk, E. H., & Velde, A. A. T. (2016) · Journal of Gastroenterology and Hepatology · doi:10.1111/jgh.13342 · Cited by 37

Mechanistic roles of epithelial and immune cell signaling during the development of colitis-associated cancer

Subramaniam, R., Mizoguchi, A., & Mizoguchi, E. (2016) · Cancer Research Frontiers · doi:10.17980/2016.1 · Cited by 39

Brewers’ rice modulates oxidative stress in azoxymethane-mediated colon carcinogenesis in rats

Tan, B. L. (2015) · World Journal of Gastroenterology · doi:10.3748/wjg.v21.i29.8826 · Cited by 37

Biomarkers for colitis-associated colorectal cancer

Chen, R., Lai, L. A., Brentnall, T. A., & Pan, S. (2016) · World Journal of Gastroenterology · doi:10.3748/wjg.v22.i35.7882 · Cited by 38

iRGD-functionalized PEGylated Nanoparticles for Enhanced Colon Tumor Accumulation and Targeted Drug Delivery

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STAT1 is a sex‐specific tumor suppressor in colitis‐associated colorectal cancer

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