Therapy of Type 2 Diabetes
Open accessAbstract
The Clinical Practice Guidelines of the German Diabetes Society/Deutsche Diabetes Gesellschaft (DDG) together with the German Society for Internal Medicine/Deutschen Gesellschaft für Innere Medizin (DGIM) are based on the contents of the National Treatment Guideline (Nationale Versorgungsleitlinie (NVL)) “Type 2 Diabetes” [ 1 ]. The modifications in therapy and their justifications made in the present Clinical Practice Guidelines were updated on the basis of new randomized controlled trials (RCTs) and meta-analyses. In order to improve the work with the extensive practice guideline in practice, the authors have decided to move the individual glucose-lowering pharmaceuticals and some algorithms in the current practice guideline to a detailed appendix. The corresponding bibliography can also be found in the appendix. Publication History Article published online: 15 July 2022 © 2022. Thieme. All rights reserved. Georg Thieme Verlag KG Rüdigerstraße 14, 70469 Stuttgart, Germany
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Patient self-management and adherence to a healthy lifestyle are crucial to reduce complex pharmacotherapy and the development and progression of diabetic complications.
“In order to reduce the complex pharmacotherapy and the development and progression of diabetic complications, patient self-management and adherence to a healthy lifestyle are crucial [28].”
From Evaluation of the Impact of Mobile Health App Vitadio in Patients With Type 2 Diabetes: Randomized Controlled Trial (2025) · cites this paper as [28]
Therapy goals in patients with type 2 diabetes should go beyond HbA1c control and address other cardiovascular risk factors.
“According to the German Diabetes Association Clinical Practice Guidelines, therapy goals in patients with type 2 diabetes should go beyond HbA1c control and address other cardiovascular risk factors [28].”
From Evaluation of the Impact of Mobile Health App Vitadio in Patients With Type 2 Diabetes: Randomized Controlled Trial (2025) · cites this paper as [28]
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Pasternak, B., Wintzell, V., Eliasson, B., Svensson, A., Franzén, S., Guðbjörnsdóttir, S., Hveem, K., Jonasson, C., Melbye, M., Svanström, H., et al. (2020) · Diabetes Care · doi:10.2337/dc19-2088 · Cited by 68 · see citing works
The effects of popular diets on type 2 diabetes management
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Thakur, S., Daley, B., & Kłubo-Gwieździńska, J. (2019) · Journal of Molecular Endocrinology · doi:10.1530/jme-19-0083 · Cited by 62 · see citing works
Perkovic, V., Toto, R., Cooper, M. E., Mann, J. F. E., Rosenstock, J., McGuire, D. K., Kahn, S. E., Marx, N., Alexander, J. H., Zinman, B., et al. (2020) · Diabetes Care · doi:10.2337/dc20-0279 · Cited by 62 · see citing works
Köhler, S., Kaspers, S., Salsali, A., Zeller, C., & Woerle, H. J. (2018) · Diabetes Care · doi:10.2337/dc17-1525 · Cited by 58 · see citing works
Huang, C., & Lee, J. (2020) · Diabetes, Obesity and Metabolism · doi:10.1111/dom.14159 · Cited by 57 · see citing works
Husain, M., Bain, S. C., Holst, A. G., Mark, T., Rasmussen, S., & Lingvay, I. (2020) · Cardiovascular Diabetology · doi:10.1186/s12933-020-01106-4 · Cited by 55 · see citing works
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Does lower limb amputation concern all SGLT2 inhibitors?
Scheen, A. J. (2018) · Nature Reviews Endocrinology · doi:10.1038/s41574-018-0001-9 · Cited by 50 · see citing works
Unick, J. L., Gaussoin, S. A., Hill, J. O., Jakicic, J. M., Bond, D. S., Hellgren, M. I., Johnson, K., Peters, A. L., Coday, M., Kitzman, D. W., et al. (2017) · Obesity · doi:10.1002/oby.21971 · Cited by 48 · see citing works
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Bonora, B. M., Avogaro, A., & Fadini, G. P. (2021) · Journal of Endocrinological Investigation · doi:10.1007/s40618-021-01515-6 · Cited by 48 · see citing works
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Monami, M., Liïstro, F., Scatena, A., Nreu, B., & Mannucci, E. (2018) · Diabetes Obesity and Metabolism · doi:10.1111/dom.13221 · Cited by 45 · see citing works
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Preeclampsia and Obesity—The Preventive Role of Exercise
Poniedziałek‐Czajkowska, E., Mierzyński, R., & Leszczyńska‐Gorzelak, B. (2023) · International Journal of Environmental Research and Public Health · doi:10.3390/ijerph20021267 · Cited by 69 · see citing works
Jung, H., Tittel, S. R., Schloot, N. C., Heitmann, E., Otto, T., Lebrec, J., Pavel, M., & Lanzinger, S. (2023) · Diabetes Obesity and Metabolism · doi:10.1111/dom.15038 · Cited by 23 · see citing works
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“Orientation parameters for therapeutic goals have been established for weight loss (for BMI from 27-35 kg/m 2 : >5% weight reduction; for BMI >35 kg/m 2 : >10% weight reduction), systolic blood pressure (120-140 mm Hg), and diastolic blood pressure (<80 mm Hg; not <70 mm Hg) [28,29].”
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Utilizing Semaglutide for Addressing Type-2 Diabetes and Obesity
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Erklärtes Ziel: Remission des Typ-2-Diabetes
Kempf, K., & Röhling, M. (2023) · Info Diabetologie · doi:10.1007/s15034-023-4536-z
- Authors
- Landgraf, R., Aberle, J., Birkenfeld, A. L., Gallwitz, B., Kellerer, M., Klein, H., Müller-Wieland, D., Nauck, M. A., Wiesner, T., & Siegel, E.
- Affiliations
- Deutsche Diabetes Stiftung (DE)
- Universität Hamburg (DE)
- German Center for Diabetes Research (DE)
- Universitätsklinikum Tübingen (DE)
- Marienhospital Stuttgart (DE)
- BG University Hospital Bergmannsheil Bochum (DE)
- Department of Internal Medicine I, University Hospital RWTH, Aachen, Germany
- St. Josef-Hospital (DE)
- MVZ Metabolic Medicine Leipzig, Leipzig, Germany
- Department of Internal Medicine – Gastroenterology, Diabetology/Endocrinology and Nutritional Medicine, St. Josefkrankenhaus Heidelberg GmbH, Heidelberg, Germany
- Corresponding author
- Landgraf, Rüdiger
- ORCID
- Venue
- Experimental and Clinical Endocrinology & Diabetes
- Publisher
- Georg Thieme Verlag KG
- Published
- 2022-07-15
- Volume
- 130
- Issue
- S 01
- Pages
- S80-S112
- ISSN
- 0947-7349 (ISSN-L)
- 1439-3646
- OpenAlex
- W4285589434
- Cited by
- 12
- References
- 245
- Citations by year
- 2025: 5 · 2024: 3 · 2023: 4
- FWCI
- 2.22
- Type
- journal article
- Language
- en
- Open access
- bronze
- doi.org
- Locations
- Experimental and Clinical Endocrinology & Diabetes (publishedVersion)
- PubMed (publishedVersion)
- Topics
- Health Sciences › Medicine › Endocrinology, Diabetes and Metabolism › Diabetes Treatment and Management
- Health Sciences › Medicine › Endocrinology, Diabetes and Metabolism › Diabetes Management and Research
- Health Sciences › Medicine › Endocrinology, Diabetes and Metabolism › Diabetes, Cardiovascular Risks, and Lipoproteins
- Keywords
- type 2 diabetes, diabetes treatment, antidiabetic drugs, treatment algorithm
- MeSH terms
- Diabetes Mellitus, Type 2, Humans, Hypoglycemic Agents, Insulin
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Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
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