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Inflammatory Bowel Disease
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“The pathogenesis of IBD involves an abnormal immune response, likely to environmental factors, in genetically susceptible individuals62.”
From Diet and the Intestinal Microbiome: Associations, Functions, and Implications for Health and Disease (2014) · cites this paper as [62]
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“Inflammatory Bowel diseases (IBDs) is a chronic immunemediated condition of the gastrointestinal tract (Abraham and Cho, 2009).”
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“002 Idescribe 2 chronic inflammatory disorders of the gut, namely ulcerative colitis and Crohn’s disease.(1) Although the etiology of IBD remains unknown, accumulating evidence has suggested that the pathologic process results from an interaction between environmental and genetic factors, which trigger an excessive in…”
BackgroundControlled release of cytokines using silk-biomaterials for macrophage polarization
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“Alicaforsen: Intercellular Adhesion Molecule-1 Antisense Oligonucleotide IBD are chronic, immune-mediated diseases of the gastrointestinal tract, which are characterized by tissue damage and development of local and extra-intestinal lesions (Abraham and Cho, 2009; Neurath, 2017).”
BackgroundApplication and Mechanisms of Triptolide in the Treatment of Inflammatory Diseases—A Review
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“Inflammatory Bowel Disease Inflammatory bowel disease (IBD) includes ulcerative colitis and Crohn’s disease (CD) and is characterized by chronic inflammation of the gastrointestinal tract (Abraham and Cho, 2009).”
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Th17 Cells in Inflammatory Bowel Disease: Cytokines, Plasticity, and Therapies
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Immunoregulatory pathways involved in inflammatory bowel disease
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High School Diet and Risk of Crohnʼs Disease and Ulcerative Colitis
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Immune markers and differential signaling networks in ulcerative colitis and Crohnʼs disease
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Histologic Evaluation of Ulcerative Colitis
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Impact of air pollution on intestinal redox lipidome and microbiome
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Farnesoid X receptor (FXR) activation and FXR genetic variation in inflammatory bowel disease
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Roles of Autophagy-Related Genes in the Pathogenesis of Inflammatory Bowel Disease
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Bile acids as inflammatory mediators and modulators of intestinal permeability
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Environmental Triggers for Inflammatory Bowel Disease
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“Nevertheless, known risk loci convey less than a third of the risk for either disease [2].”
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Ulcerative Colitis: Current and Emerging Treatment Strategies
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Sleep Duration Affects Risk for Ulcerative Colitis: A Prospective Cohort Study
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Abnormal Small Intestinal Epithelial Microvilli in Patients With Crohn's Disease
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“Of the 9 gene clusters generated, 4 were relatively upregulated (1, 3, 6, 8) and 5 were relatively down-regulated (2, 4, 5, 7, and 9) in CD vs.”
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Metadata
- Authors
- Abraham, C., & Cho, J. H.
- Affiliations
- Yale University (US)
- Venue
- New England Journal of Medicine
- Publisher
- Massachusetts Medical Society
- Published
- 2009-11-19
- Volume
- 361
- Issue
- 21
- Pages
- 2066-2078
- ISSN
- 0028-4793 (ISSN-L)
- 1533-4406
- PMC
- PMC3491806
- OpenAlex
- W4244626580
- Cited by
- 2,712
- References
- 104
- Citations by year
- 2026: 94 · 2025: 137 · 2024: 169 · 2023: 151 · 2022: 171 · 2021: 184 · 2020: 237 · 2019: 189 · 2018: 193 · 2017: 182 · 2016: 171 · 2015: 217 · 2014: 174 · 2013: 142 · 2012: 120
- FWCI
- 9.21
- Type
- journal article
- Language
- en
- Open access
- bronze
- doi.org
- Locations
- New England Journal of Medicine (publishedVersion)
- PubMed (publishedVersion)
- Europe PMC (PubMed Central) (acceptedVersion)
- PubMed Central (acceptedVersion)
- Funders
- Crohn's and Colitis Foundation of America (DK062422, R01DK077905)
- Crohn's and Colitis Foundation
- National Institutes of Health (DK P30-34989, U01 DK62429)
- Takeda Oncology
- National Institute of Diabetes and Digestive and Kidney Diseases (DK P30 34989, U01-DK62429, R01DK072373, R01DK077905, RC1DK086800, U01DK062429, P30DK034989, U01DK062422)
- National Center for Research Resources (UL1RR024139)
- Topics
- Health Sciences › Medicine › Gastroenterology › Inflammatory Bowel Disease
- Health Sciences › Medicine › Ophthalmology › Ocular Diseases and Behçet’s Syndrome
- Health Sciences › Medicine › Dermatology › Autoimmune and Inflammatory Disorders
- Keywords
- inflammatory bowel disease
- MeSH terms
- Animals, Colitis, Ulcerative, Crohn Disease, Humans, Immunity, Innate, Intestinal Mucosa, T-Lymphocytes, Inflammatory Bowel Diseases, Interleukin-23, Metagenome
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