The DOI matches its Crossref record; 109 of the 109 references it cites were found in a registry or an index.
Inflammatory Bowel Disease
Open accessAbstract
more than 50 distinct clinical collections, which can be used as convenient entry points to clinical content.In each collection, articles are cited in reverse chronologic order, with the most recent first.
Overview
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Integrity signals
Registry
Cites
Statistics
Verification
Claims the paper makes
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Claims other papers make about this one
Each is checked against this paper’s own text: does it say what the citing paper says it does?
In the citing paper
“The pathogenesis of IBD involves an abnormal immune response, likely to environmental factors, in genetically susceptible individuals62.”
From Diet and the Intestinal Microbiome: Associations, Functions, and Implications for Health and Disease (2014) · cites this paper as [62]
Self-check
Percentages, sums and reported differences re-computed from the paper’s own numbers.
The self-check needs the paper’s full text.
Citations
Cites
Genome-wide association study of 14,000 cases of seven common diseases and 3,000 shared controls
The Wellcome Trust Case Control Consortium, Management Committee, Burton, P. R., Clayton, D. G., Cardon, L. R., Craddock, N., Deloukas, P., Duncanson, A., Kwiatkowski, D. P., McCarthy, M. I., et al. (2007) · Nature · doi:10.1038/nature05911 · Cited by 9,442
A core gut microbiome in obese and lean twins
Turnbaugh, P. J., Hamady, M., Yatsunenko, T., Cantarel, B. L., Duncan, A., Ley, R. E., Sogin, M. L., Jones, W. J., Roe, B. A., Affourtit, J. P., et al. (2009) · Nature · doi:10.1038/nature07540 · Cited by 7,823
Host-Bacterial Mutualism in the Human Intestine
Bäckhed, F., Ley, R. E., Sonnenburg, J. L., Peterson, D. A., & Gordon, J. I. (2005) · Science · doi:10.1126/science.1104816 · Cited by 5,277
Frank, D. N., St. Amand, A. L., Feldman, R. A., Boedeker, E. C., Harpaz, N., & Pace, N. R. (2007) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0706625104 · Cited by 4,611
Recognition of Commensal Microflora by Toll-Like Receptors Is Required for Intestinal Homeostasis
Rakoff-Nahoum, S., Paglino, J., Eslami-Varzaneh, F., Edberg, S., & Medzhitov, R. (2004) · Cell · doi:10.1016/j.cell.2004.07.002 · Cited by 4,251
Tuberculosis Associated with Infliximab, a Tumor Necrosis Factor α–Neutralizing Agent
Keane, J., Gershon, S. K., Wise, R. P., Mirabile‐Levens, E., Kasznica, J. M., Schwieterman, W. D., Siegel, J. N., & Braun, M. M. (2001) · New England Journal of Medicine · doi:10.1056/nejmoa011110 · Cited by 3,683
Transforming growth factor-β induces development of the TH17 lineage
Mangan, P. R., Harrington, L. E., O'Quinn, D. B., Helms, W. S., Bullard, D. C., Elson, C. O., Hatton, R. D., Wahl, S. M., Schoeb, T. R., & Weaver, C. T. (2006) · Nature · doi:10.1038/nature04754 · Cited by 3,087
A Genome-Wide Association Study Identifies IL23R as an Inflammatory Bowel Disease Gene
Duerr, R. H., Taylor, K. D., Brant, S. R., Rioux, J. D., Silverberg, M. S., Daly, M. J., Steinhart, A. H., Abraham, C., Regueiro, M., Griffiths, A., et al. (2006) · Science · doi:10.1126/science.1135245 · Cited by 3,039
Genome-wide association defines more than 30 distinct susceptibility loci for Crohn's disease
the NIDDK IBD Genetics Consortium, Barrett, J. C., the Belgian-French IBD Consortium, the Wellcome Trust Case Control Consortium, Hansoul, S., Nicolae, D. L., Cho, J. H., Duerr, R. H., Rioux, J. D., Brant, S. R., et al. (2008) · Nature Genetics · doi:10.1038/ng.175 · Cited by 2,593
Rescigno, M., Urbano, M., Valzasina, B., Francolini, M., Rotta, G., Bonasio, R., Granucci, F., Kraehenbuhl, J.-P., & Ricciardi‐Castagnoli, P. (2001) · Nature Immunology · doi:10.1038/86373 · Cited by 2,554
Flagged first, then by citations
Cited by
Sorted by citations
Items 401–500 of 1,008
Targeting interleukin-17 in chronic inflammatory disease: A clinical perspective
Zwicky, P., Unger, S., & Becher, B. (2020) · Journal of Experimental Medicine · doi:10.1084/jem.20191123 · Cited by 91
Sevrin, G., Massier, S., Chassaing, B., Agus, A., Delmas, J., Denizot, J., Billard, E., & Barnich, N. (2018) · Gut Microbes · doi:10.1080/19490976.2017.1421886 · Cited by 98
Role of Vitamin D in the Natural History of Inflammatory Bowel Disease
Nielsen, O. H., Rejnmark, L., & Moss, A. C. (2018) · Journal of Crohn s and Colitis · doi:10.1093/ecco-jcc/jjy025 · Cited by 97
Time to dissect the autoimmune etiology of cancer antibody immunotherapy
Dougan, M. L., & Pietropaolo, M. (2020) · Journal of Clinical Investigation · doi:10.1172/jci131194 · Cited by 92
Endothelial dysfunction and its relation in different disorders: Recent update
Ray, A., Maharana, K. C., Meenakshi, S., & Singh, S. (2023) · Health Sciences Review · doi:10.1016/j.hsr.2023.100084 · Cited by 91
Ou, C. ‐., Kuo, H., Wang, L., Hsu, T. ‐., Chuang, H., Liu, C. ‐., Chang, J., Yu, H., & Yang, K. D. (2012) · Clinical & Experimental Allergy · doi:10.1111/j.1365-2222.2012.04037.x · Cited by 91
Yao, W., Gong, J., Zhu, W., Tian, H., Ding, C., Gu, L., Li, N., & Li, J. (2016) · BMC Microbiology · doi:10.1186/s12866-016-0869-2 · Cited by 97
The Plasma Membrane: A Platform for Intra- and Intercellular Redox Signaling
Nordzieke, D. E., & Medraño-Fernandez, I. (2018) · Antioxidants · doi:10.3390/antiox7110168 · Cited by 90
The matricellular protein CCN1 in tissue injury repair
Kim, K., Won, J. H., Cheng, N., & Lau, L. F. (2018) · Journal of Cell Communication and Signaling · doi:10.1007/s12079-018-0450-x · Cited by 89
Dou, W., Zhang, J., Li, H., Kortagere, S., Sun, K., Ding, L., Ren, G., Wang, Z., & Mani, S. (2014) · The Journal of Nutritional Biochemistry · doi:10.1016/j.jnutbio.2014.04.006 · Cited by 90
Powell, N., Lo, J. W., Biancheri, P., Vossenkämper, A., Pantazi, E. D., Walker, A. W., Stolarczyk, É., Ammoscato, F., Goldberg, R., Scott, P., et al. (2015) · Gastroenterology · doi:10.1053/j.gastro.2015.04.017 · Cited by 86
Assessment of mucosal healing in inflammatory bowel disease: review
Dulai, P. S., Levesque, B. G., Feagan, B. G., D’Haens, G., & Sandborn, W. J. (2015) · Gastrointestinal Endoscopy · doi:10.1016/j.gie.2015.03.1974 · Cited by 89
JAK inhibition in inflammatory bowel disease
Olivera, P. A., Danese, S., & Peyrin‐Biroulet, L. (2017) · Expert Review of Clinical Immunology · doi:10.1080/1744666x.2017.1291342 · Cited by 89
Inflammatory bowel disease and its treatment in 2018: Global and Taiwanese status updates
Su, H.-J., Chiu, Y., Chiu, C.-T., Lin, Y.-C., Wang, C., Hsieh, J.-Y., & Wei, S. (2018) · Journal of the Formosan Medical Association · doi:10.1016/j.jfma.2018.07.005 · Cited by 89
Eder, P., Adler, M., Dobrowolska, A., Kamhieh‐Milz, J., & Witowski, J. (2019) · Cells · doi:10.3390/cells8060628 · Cited by 88
CD13/Aminopeptidase N Is a Potential Therapeutic Target for Inflammatory Disorders
Lu, C., Amin, M. A., & Fox, D. A. (2019) · The Journal of Immunology · doi:10.4049/jimmunol.1900868 · Cited by 91
Inflammatory Bowel Disease: The Classic Gastrointestinal Autoimmune Disease
Kaistha, A., & Levine, J. J. (2014) · Current problems in pediatric and adolescent health care · doi:10.1016/j.cppeds.2014.10.003 · Cited by 89
Dhillon, S. S., Mastropaolo, L. A., Murchie, R., Griffiths, C., Thoeni, C. E., Elkadri, A. A., Xu, W., Mack, A., Walters, T. D., Guo, C., et al. (2014) · Clinical and Translational Gastroenterology · doi:10.1038/ctg.2013.17 · Cited by 85
Weckbach, L. T., Muramatsu, T., & Walzog, B. (2011) · The Scientific World JOURNAL · doi:10.1100/2011/517152 · Cited by 89
Ananthakrishnan, A. N., Huang, H., Nguyen, D. D., Sauk, J. S., Yajnik, V., & Xavier, R. J. (2014) · The American Journal of Gastroenterology · doi:10.1038/ajg.2013.464 · Cited by 89
Caetano, M. A. F., & Castelucci, P. (2022) · World Journal of Clinical Cases · doi:10.12998/wjcc.v10.i28.9985 · Cited by 92
Chan, S. S. M., Luben, R., Olsen, A., Tjønneland, A. M., Kaaks, R., Lindgren, S. C., Grip, O., Bergmann, M. M., Boeing, H., Hallmans, G., et al. (2014) · Alimentary Pharmacology & Therapeutics · doi:10.1111/apt.12670 · Cited by 93
Lau, K. S., Juchheim, A. M., Cavaliere, K., Philips, S. R., Lauffenburger, D. A., & Haigis, K. M. (2011) · Science Signaling · doi:10.1126/scisignal.2001338 · Cited by 87
Mao, H., Yang, W., Lee, P. P. W., Ho, M., Yang, J., Zeng, S., Chong, C.-Y., Lee, T.-L., Tu, W., & Lau, Y.-L. (2012) · Genes and Immunity · doi:10.1038/gene.2012.8 · Cited by 87
Gut microbiome: a new player in gastrointestinal disease
Gorkiewicz, G., & Moschen, A. R. (2017) · Archiv für Pathologische Anatomie und Physiologie und für Klinische Medicin · doi:10.1007/s00428-017-2277-x · Cited by 95
Selenium and Selenoproteins in Gut Inflammation—A Review
Nettleford, S. K., & Prabhu, K. S. (2018) · Antioxidants · doi:10.3390/antiox7030036 · Cited by 87
Silva, I., Pinto, R. M. A., & Mateus, V. (2019) · Journal of Clinical Medicine · doi:10.3390/jcm8101574 · Cited by 87
Heim, V. J., Stafford, C. A., & Nachbur, U. (2019) · Frontiers in Cell and Developmental Biology · doi:10.3389/fcell.2019.00208 · Cited by 89
“The strongest evidence that suggests direct involvement of NOD signaling pathways in regulating caspase functions stem from observations that NOD1 and NOD2 can induce IL-1β through NF-κB and MAPK pathways in multiple human and mouse cell populations, including myeloid-derived cells (Li et al., 2004; Watanabe et al., 2…”
BackgroundArginase impedes the resolution of colitis by altering the microbiome and metabolome
Baier, J., Gänsbauer, M., Gießler, C., Arnold, H., Muske, M., Schleicher, U., Lukassen, S., Ekici, A. B., Rauh, M., Daniel, C., et al. (2020) · Journal of Clinical Investigation · doi:10.1172/jci126923 · Cited by 87
“Both inflammatory bowel diseases (IBDs) are thought to result from dysregulated interactions of the commensal microbiota, the intestinal epithelium (IE), and the mucosal humoral and cellular immune network (1).”
BackgroundPurysko, A. S., Remer, E. M., Filho, H. M. L., Bittencourt, L. K., Lima, R. V., & Racy, D. J. (2011) · Radiographics · doi:10.1148/rg.314105065 · Cited by 87
Nguyen, T. T., Trinh, N., Tran, H. N., Tran, H. T., Le, P. Q., Ngo, D., Tran‐Van, H., Toi, V. V., Vong, L. B., & Nagasaki, Y. (2020) · Journal of Controlled Release · doi:10.1016/j.jconrel.2020.10.042 · Cited by 89
Engler, D. B., Leonardi, I., Hartung, M. L., Kyburz, A., Spath, S., Becher, B., Rogler, G., & Mueller, A. (2015) · Inflammatory Bowel Diseases · doi:10.1097/mib.0000000000000318 · Cited by 86
Song, J.-Y., Kang, H. J., Hong, J. S., Kim, C. J., Shim, J., Lee, C. W., & Choi, J. (2017) · Scientific Reports · doi:10.1038/s41598-017-09827-5 · Cited by 86
An Update of Research Animal Models of Inflammatory Bowel Disease
Baydi, Z., Limami, Y., Khalki, L., Zaïd, N., Naya, A., Mtairag, E. M., Oudghiri, M., & Zaid, Y. (2021) · The Scientific World JOURNAL · doi:10.1155/2021/7479540 · Cited by 86
“In 1975, the propagation of ten lines of “senescenceprone” mice SAMP1 [72] resulted from brother-sister mating with a selection of breeders with accelerated senescence, shortened life span, and other signs of pathology.”
BackgroundEPA- and DHA-derived resolvins' actions in inflammatory bowel disease
Schwanke, R. C., Marcon, R., Bento, A. F., & Calixto, J. Β. (2015) · European Journal of Pharmacology · doi:10.1016/j.ejphar.2015.08.050 · Cited by 85
“…still remains elusive, but a large amount of evidence suggests that genetic factors increase the susceptibility to it, and environmental factors seem to be responsible for the onset of the disease (Abraham and Cho, 2009; Baumgart et al., 2010; Strober et al., 2007; Xavier and Podolsky, 2007).”
BackgroundHolmer, A. K., & Singh, S. (2019) · Expert Review of Clinical Immunology · doi:10.1080/1744666x.2019.1646127 · Cited by 84
Advances in Fecal Microbiota Transplantation for Gut Dysbiosis‐Related Diseases
Hou, S., Yu, J., Li, Y., Zhao, D., & Zhang, Z. (2025) · Advanced Science · doi:10.1002/advs.202413197 · Cited by 97
Shores, D. R., Binion, D. G., Freeman, B. Α., & Baker, P. R. S. (2010) · Inflammatory Bowel Diseases · doi:10.1002/ibd.21560 · Cited by 86
The Membrane-Bound Mucin Muc1 Regulates T Helper 17-Cell Responses and Colitis in Mice
Nishida, A., Lau, C. W., Zhang, M., Andoh, A., Shi, H. N., Mizoguchi, E., & Mizoguchi, A. (2011) · Gastroenterology · doi:10.1053/j.gastro.2011.12.036 · Cited by 84
Pringle, P. L., Stewart, K. O., Peloquin, J. M., Sturgeon, H. C., Nguyen, D. D., Sauk, J. S., Garber, J. J., Yajnik, V., Ananthakrishnan, A. N., Chan, A. T., et al. (2015) · Inflammatory Bowel Diseases · doi:10.1097/mib.0000000000000498 · Cited by 86
Qiao, H., Fang, D., Chen, J., Sun, Y., Chen, K., Di, L., Li, J., Chen, Z., Chen, J., & Gao, Y. (2017) · Drug Delivery · doi:10.1080/10717544.2016.1245367 · Cited by 84
Szigethy, E., McLafferty, L. P., & Goyal, A. (2010) · Child and Adolescent Psychiatric Clinics of North America · doi:10.1016/j.chc.2010.01.007 · Cited by 84
Lemoine, R., Schmid, J. P., Farin, H. F., Bigorgne, A., Debré, M., Sepulveda, F. E., Héritier, S., Lemale, J., Talbotec, C., Rieux‐Laucat, F., et al. (2014) · Journal of Allergy and Clinical Immunology · doi:10.1016/j.jaci.2014.07.019 · Cited by 84
T Cell–Macrophage Interactions and Granuloma Formation in Vasculitis
Hilhorst, M. L., Shirai, T., Berry, G. J., Goronzy, J. J., & Weyand, C. M. (2014) · Frontiers in Immunology · doi:10.3389/fimmu.2014.00432 · Cited by 84
Pathogenesis and biomarkers of carcinogenesis in ulcerative colitis
Þorsteinsdóttir, S., Guðjόnsson, Þ., Nielsen, O. H., Vainer, B., & Seidelin, J. B. (2011) · Nature Reviews Gastroenterology & Hepatology · doi:10.1038/nrgastro.2011.96 · Cited by 83
Huang, Z. D., Gan, J., Jia, L., Guo, G., Wang, C., Zang, Y., Ding, Z., Chen, J., Zhang, J., & Dong, L. (2015) · Biomaterials · doi:10.1016/j.biomaterials.2015.01.013 · Cited by 83
Emerging actions of the nuclear receptor LRH-1 in the gut
Fernández-Marcos, P. J., Auwerx, J. H., & Schoonjans, K. (2010) · Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease · doi:10.1016/j.bbadis.2010.12.010 · Cited by 83
Control of inflammation by stromal Hedgehog pathway activation restrains colitis
Lee, J. J., Rothenberg, M. E., Seeley, E. S., Zimdahl, B., Kawano, S., Lu, W.-J., Shin, K., Sakata, T., Chen, J., Diehn, M., et al. (2016) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1616447113 · Cited by 83
Lahiri, A., & Abraham, C. (2014) · Gastroenterology · doi:10.1053/j.gastro.2014.06.024 · Cited by 84
Microbiome of the Paranasal Sinuses: Update and Literature Review
Lee, J. T., Frank, D. N., & Ramakrishnan, V. R. (2016) · American Journal of Rhinology and Allergy · doi:10.2500/ajra.2016.30.4255 · Cited by 82
Mezzasalma, V., Manfrini, E., Ferri, E., Sandionigi, A., La Ferla, B., Schiano, I., Michelotti, A., Nobile, V., Labra, M., & Di Gennaro, P. (2016) · BioMed Research International · doi:10.1155/2016/4740907 · Cited by 81
Helminths and the microbiota: parts of the hygiene hypothesis
Loke, P., & Lim, Y. A. L. (2015) · Parasite Immunology · doi:10.1111/pim.12193 · Cited by 80
Eckert, K. G., Abbasi-Neureither, I., Köppel, M., & Huber, G. (2019) · BMC Gastroenterology · doi:10.1186/s12876-019-1034-9 · Cited by 81
Kim, S. W., Kim, S., Son, M., Cheon, J. H., & Park, Y. S. (2020) · Scientific Reports · doi:10.1038/s41598-020-59314-7 · Cited by 81
Han, R., Ma, Y., Xiao, J., You, L., Pedišić, S., & Liao, L. (2021) · Food and Chemical Toxicology · doi:10.1016/j.fct.2021.112001 · Cited by 81
Lin, J., Welker, N. C., Zhao, Z., Li, Y., Zhang, J., Reuss, S. A., Zhang, X., Lee, H., Liu, Y., & Bronner, M. P. (2013) · Modern Pathology · doi:10.1038/modpathol.2013.152 · Cited by 81
Piras, V., Usai, P., Mezzena, S., Susnik, M., Ideo, F., Schirru, E., & Cotti, E. (2017) · Journal of Endodontics · doi:10.1016/j.joen.2016.11.004 · Cited by 80
Local drug delivery systems for inflammatory diseases: Status quo, challenges, and opportunities
Chen, Y.-C., Gad, S. F., Chobisa, D., Li, Y., & Yeo, Y. (2020) · Journal of Controlled Release · doi:10.1016/j.jconrel.2020.12.025 · Cited by 80
“Disease (CD) and Ulcerative Colitis (UC), describes a group of intestinal disorders resulting from inappropriate inflammatory response to intestinal microorganisms in genetically sensitive patients [279].”
BackgroundNOD-like receptors in intestinal homeostasis and epithelial tissue repair
Parlato, M., & Yeretssian, G. (2014) · International Journal of Molecular Sciences · doi:10.3390/ijms15069594 · Cited by 79
Khanna, R., Bouguen, G., Feagan, B. G., D’Haens, G., Sandborn, W. J., Dubcenco, E., Baker, K. A., & Levesque, B. G. (2014) · Inflammatory Bowel Diseases · doi:10.1097/mib.0000000000000131 · Cited by 79
Wadsworth, W. D., Argiento, R., Guindani, M., Galloway-Peña, J., Shelburne, S. A., & Vannucci, M. (2017) · BMC Bioinformatics · doi:10.1186/s12859-017-1516-0 · Cited by 84
Sahoo, D., Swanson, L., Sayed, I. M., Katkar, G. D., Ibeawuchi, S.-R., Mittal, Y., Pranadinata, R. F., Tindle, C., Fuller, M., Stec, D. L., et al. (2021) · Nature Communications · doi:10.1038/s41467-021-24470-5 · Cited by 81
Intestinal Alkaline Phosphatase: A Review of This Enzyme Role in the Intestinal Barrier Function
Santos, G. M., Ismael, S., Morais, J., Araújo, J., Faria, A., Calhau, C., & Marques, C. (2022) · Microorganisms · doi:10.3390/microorganisms10040746 · Cited by 73
Mortha, A., Remark, R., Valle, D. M. D., Chuang, L.-S. F., Chai, Z., Alves, I., Azevedo, C. M., Gaifem, J., Martin, J., Petralia, F., et al. (2022) · Gastroenterology · doi:10.1053/j.gastro.2022.05.029 · Cited by 79
Interleukin-34 sustains inflammatory pathways in the gut
Franzè, E., Monteleone, I., Cupi, M. L., Mancia, P., Caprioli, F., Marafini, I., Colantoni, A., Ortenzi, A., Laudisi, F., Sica, G., et al. (2015) · Clinical Science · doi:10.1042/cs20150132 · Cited by 79
The multiple and enigmatic roles of guanylyl cyclase C in intestinal homeostasis
Arshad, N., & Visweswariah, S. S. (2012) · FEBS Letters · doi:10.1016/j.febslet.2012.07.028 · Cited by 76
Deshpande, N., Lutz, A. M., Ren, Y., Foygel, K., Tian, L., Schneider, M., Pai, R. K., Pasricha, P. J., & Willmann, J. K. (2011) · Radiology · doi:10.1148/radiol.11110323 · Cited by 79
Ferrari, D., Cimino, F., Fratantonio, D., Molonia, M. S., Bashllari, R., Busà, R., Saija, A., & Speciale, A. (2017) · Mediators of Inflammation · doi:10.1155/2017/3454023 · Cited by 79
Kim, D. H., Kim, S., Lee, J. H., Kim, J. H., Che, X., Woo, H. J., Seo, D. H., Kim, T. I., Kim, W. H., Kim, S. W., et al. (2018) · Journal of Gastroenterology and Hepatology · doi:10.1111/jgh.14362 · Cited by 78
Psychological co-morbidities in COPD: Targeting systemic inflammation, a benefit for both?
Pelgrim, C. E., Peterson, J. D., Gosker, H. R., Schols, A. M. W. J., van Helvoort, A., Garssen, J., Folkerts, G., & Kraneveld, A. D. (2018) · European Journal of Pharmacology · doi:10.1016/j.ejphar.2018.10.001 · Cited by 85
“It is believed that gut inflammation in IBD is driven by an inefficient immune response to bacterial antigens, largely regulated by the gut microbiome (Abraham and Cho, 2009).”
BackgroundLiu, Q., Zuo, R. M., Wang, K., Nong, F., Fu, Y.-J., Huang, S., Pan, Z., Zhang, Y., Luo, X., Deng, X., et al. (2020) · Acta Pharmacologica Sinica · doi:10.1038/s41401-019-0335-4 · Cited by 78
Epidemiological and clinical characteristics of inflammatory bowel diseases in Cairo, Egypt
Esmat, S. (2014) · World Journal of Gastroenterology · doi:10.3748/wjg.v20.i3.814 · Cited by 78
Murine Models of Inflammatory Bowel Disease (IBD)
DeVoss, J., & Diehl, L. J. (2013) · Toxicologic Pathology · doi:10.1177/0192623313509729 · Cited by 78
Gardenbroek, T. J., Pinkney, T. D., Sahami, S., Morton, D. G., Buskens, C. J., Ponsioen, C. Y., Tanis, P. J., Löwenberg, M., BRINK, G. R. V. D., Broeders, I. A. M. J., et al. (2015) · BMC Surgery · doi:10.1186/s12893-015-0017-1 · Cited by 78
Helicobacter pyloriinfection and inflammatory bowel disease in Asians: A meta-analysis
Wu, X., Ji, H., Yang, M., Wu, L., & Wang, F. (2015) · World Journal of Gastroenterology · doi:10.3748/wjg.v21.i15.4750 · Cited by 78
Cytokine responses and epithelial function in the intestinal mucosa
Onyiah, J. C., & Colgan, S. P. (2016) · Cellular and Molecular Life Sciences · doi:10.1007/s00018-016-2289-8 · Cited by 86
de Bruyn, M., Vandooren, J., Ugarte-Berzal, E., Arijs, I., Vermeire, S., & Opdenakker, G. (2016) · Critical Reviews in Biochemistry and Molecular Biology · doi:10.1080/10409238.2016.1199535 · Cited by 81
Cho, Y.-C., Park, J., & Cho, S. (2020) · International Journal of Molecular Sciences · doi:10.3390/ijms21062007 · Cited by 80
Xu, C., Chen, S., Chen, C., Ming, Y., Du, J., Mu, J., Luo, F., Huang, D., Wang, N., Lin, Z., et al. (2022) · International Journal of Pharmaceutics · doi:10.1016/j.ijpharm.2022.121884 · Cited by 77
Novel perspectives on therapeutic modulation of the gut microbiota
McCarville, J. L., Caminero, A., & Verdu, E. F. (2016) · Therapeutic Advances in Gastroenterology · doi:10.1177/1756283x16637819 · Cited by 78
The T300A Crohn’s disease risk polymorphism impairs function of the WD40 domain of ATG16L1
Boada-Romero, E., Serramito-Gómez, I., Sacristán, M. P., Boone, D. L., Xavier, R. J., & Pimentel‐Muiños, F. X. (2016) · Nature Communications · doi:10.1038/ncomms11821 · Cited by 80
Lahiri, A., Hedl, M., Yan, J., & Abraham, C. (2017) · Nature Communications · doi:10.1038/ncomms15614 · Cited by 76
Dietary practices and inflammatory bowel disease
Limdi, J. K. (2018) · Indian Journal of Gastroenterology · doi:10.1007/s12664-018-0890-5 · Cited by 77
STAT1 signaling shields T cells from NK cell-mediated cytotoxicity
Kang, Y. H., Biswas, A., Field, M., & Snapper, S. B. (2019) · Nature Communications · doi:10.1038/s41467-019-08743-8 · Cited by 76
Nod2: a key regulator linking microbiota to intestinal mucosal immunity
Biswas, A., Petnicki‐Ocwieja, T., & Kobayashi, K. S. (2011) · Journal of Molecular Medicine · doi:10.1007/s00109-011-0802-y · Cited by 76
Huang, Z. D., Jiang, Y., Yang, Y., Shao, J., Sun, X., Chen, J., Dong, L., & Zhang, J. (2012) · Molecular Immunology · doi:10.1016/j.molimm.2012.09.007 · Cited by 78
Creatine maintains intestinal homeostasis and protects against colitis
Turer, E. E., McAlpine, W., Wang, K.-W., Lu, T., Li, X., Tang, M., Zhan, X., Wang, T., Zhan, X., Bu, C.-H., et al. (2017) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1621400114 · Cited by 76
Dysregulation of Group 3 Innate Lymphoid Cells in the Pathogenesis of Inflammatory Bowel Disease
Forkel, M., & Mjösberg, J. (2016) · Current Allergy and Asthma Reports · doi:10.1007/s11882-016-0652-3 · Cited by 75
Novel Pharmacological Therapy in Inflammatory Bowel Diseases: Beyond Anti-Tumor Necrosis Factor
Pagnini, C., Pizarro, T. T., & Cominelli, F. (2019) · Frontiers in Pharmacology · doi:10.3389/fphar.2019.00671 · Cited by 75
“Crohn’s disease (CD) and ulcerative colitis (UC) are the two main entities of IBD, which each presents particular clinical and anatomo-pathological features (Abraham and Cho, 2009).”
BackgroundAttenuation of bile acid-mediated FXR and PXR activation in patients with Crohn’s disease
Wilson, A. S., Almousa, A. A., Teft, W. A., & Kim, R. B. (2020) · Scientific Reports · doi:10.1038/s41598-020-58644-w · Cited by 75
Yuan, S., Kim, J. H., Xu, P., & Wang, Z. (2023) · Frontiers in Immunology · doi:10.3389/fimmu.2022.1057253 · Cited by 79
“It has more superficial inflammation than CD (3, 4).”
BackgroundSartor, R. B. (2011) · Mucosal Immunology · doi:10.1038/mi.2010.87 · Cited by 75
Acartürk, G., Acay, A., Demir, K., Mennune Sena, U. L. U., Ahsen, A., & Yüksel, Ş. (2015) · Bratislavské lekárske listy/Bratislava medical journal · doi:10.4149/bll_2015_041 · Cited by 77
“In contrast, UC is typifi ed by mucosal infl ammation and limited to the colon (2).”
BackgroundFaye, A. S., Wen, T., Soroush, A., Ananthakrishnan, A. N., Ungaro, R. C., Lawlor, G. O., Attenello, F. J., Mack, W. J., Colombel, J., & Lebwohl, B. (2021) · Digestive Diseases and Sciences · doi:10.1007/s10620-020-06746-w · Cited by 74
Horowitz, J. E., Warner, N. E., Staples, J. C., Crowley, E., Gosalia, N., Murchie, R., Hout, C. V. V., Fiedler, K. B., Welch, G., King, A. K., et al. (2021) · Scientific Reports · doi:10.1038/s41598-021-84938-8 · Cited by 80
Visceral fat and gut inflammation
Drouet, M., Dubuquoy, L., Desreumaux, P., & Bertin, B. (2011) · Nutrition · doi:10.1016/j.nut.2011.09.009 · Cited by 75
Jädert, C., Phillipson, M., Holm, L., Lundberg, J. O., & Borniquel, S. (2014) · Redox Biology · doi:10.1016/j.redox.2013.12.012 · Cited by 73
Diagnosis and management of microscopic colitis: current perspectives
Tysk, C., Bohr, J., Wickbom, A., Hegedűs, Á., Nyhlin, N., & Hörnquist, E. H. (2014) · Clinical and Experimental Gastroenterology · doi:10.2147/ceg.s63905 · Cited by 73
Dysbiotic gut microbiome: A key element of Crohn's disease
Øyri, S. F., Műzes, G., & Sípos, F. (2015) · Comparative Immunology Microbiology and Infectious Diseases · doi:10.1016/j.cimid.2015.10.005 · Cited by 78
Food avoidance in patients with inflammatory bowel disease: What, when and who?
Bergeron, F., Bouin, M., D’Aoust, L., Lemoyne, M., & Presse, N. (2017) · Clinical Nutrition · doi:10.1016/j.clnu.2017.03.010 · Cited by 73
Metadata
- Authors
- Abraham, C., & Cho, J. H.
- Affiliations
- Yale University (US)
- Venue
- New England Journal of Medicine
- Publisher
- Massachusetts Medical Society
- Published
- 2009-11-19
- Volume
- 361
- Issue
- 21
- Pages
- 2066-2078
- ISSN
- 0028-4793 (ISSN-L)
- 1533-4406
- PMC
- PMC3491806
- OpenAlex
- W4244626580
- Cited by
- 2,712
- References
- 104
- Citations by year
- 2026: 94 · 2025: 137 · 2024: 169 · 2023: 151 · 2022: 171 · 2021: 184 · 2020: 237 · 2019: 189 · 2018: 193 · 2017: 182 · 2016: 171 · 2015: 217 · 2014: 174 · 2013: 142 · 2012: 120
- FWCI
- 9.21
- Type
- journal article
- Language
- en
- Open access
- bronze
- doi.org
- Locations
- New England Journal of Medicine (publishedVersion)
- PubMed (publishedVersion)
- Europe PMC (PubMed Central) (acceptedVersion)
- PubMed Central (acceptedVersion)
- Funders
- Crohn's and Colitis Foundation of America (DK062422, R01DK077905)
- Crohn's and Colitis Foundation
- National Institutes of Health (DK P30-34989, U01 DK62429)
- Takeda Oncology
- National Institute of Diabetes and Digestive and Kidney Diseases (DK P30 34989, U01-DK62429, R01DK072373, R01DK077905, RC1DK086800, U01DK062429, P30DK034989, U01DK062422)
- National Center for Research Resources (UL1RR024139)
- Topics
- Health Sciences › Medicine › Gastroenterology › Inflammatory Bowel Disease
- Health Sciences › Medicine › Ophthalmology › Ocular Diseases and Behçet’s Syndrome
- Health Sciences › Medicine › Dermatology › Autoimmune and Inflammatory Disorders
- Keywords
- inflammatory bowel disease
- MeSH terms
- Animals, Colitis, Ulcerative, Crohn Disease, Humans, Immunity, Innate, Intestinal Mucosa, T-Lymphocytes, Inflammatory Bowel Diseases, Interleukin-23, Metagenome
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review