Cited by 2,712Inflammatory Bowel DiseaseOcular Diseases and Behçet’s SyndromeAutoimmune and Inflammatory Disorders

The DOI matches its Crossref record; 109 of the 109 references it cites were found in a registry or an index.

Inflammatory Bowel Disease

Open access

Abraham, Clara, Cho, Judy H.·2009·New England Journal of Medicine

Open this paper in CoChat — free account Open PDF

Abstract

more than 50 distinct clinical collections, which can be used as convenient entry points to clinical content.In each collection, articles are cited in reverse chronologic order, with the most recent first.

The claims and statistics of this paper haven’t been checked yet.

Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.

Integrity signals

Registry

Crossref · 10.1056/nejmra0804647

Cites

109 of 109 references verified0 citation errors · 0 not checkable

Statistics

Claims the paper makes

The claims and statistics of this paper haven’t been checked yet.

Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.

Claims other papers make about this one

Each is checked against this paper’s own text: does it say what the citing paper says it does?

Self-check

Percentages, sums and reported differences re-computed from the paper’s own numbers.

The self-check needs the paper’s full text.

Genome-wide association study of 14,000 cases of seven common diseases and 3,000 shared controls
The Wellcome Trust Case Control Consortium, Management Committee, Burton, P. R., Clayton, D. G., Cardon, L. R., Craddock, N., Deloukas, P., Duncanson, A., Kwiatkowski, D. P., McCarthy, M. I., et al. (2007) · Nature · doi:10.1038/nature05911 · Cited by 9,442
A core gut microbiome in obese and lean twins
Turnbaugh, P. J., Hamady, M., Yatsunenko, T., Cantarel, B. L., Duncan, A., Ley, R. E., Sogin, M. L., Jones, W. J., Roe, B. A., Affourtit, J. P., et al. (2009) · Nature · doi:10.1038/nature07540 · Cited by 7,823
Host-Bacterial Mutualism in the Human Intestine
Bäckhed, F., Ley, R. E., Sonnenburg, J. L., Peterson, D. A., & Gordon, J. I. (2005) · Science · doi:10.1126/science.1104816 · Cited by 5,277
Molecular-phylogenetic characterization of microbial community imbalances in human inflammatory bowel diseases
Frank, D. N., St. Amand, A. L., Feldman, R. A., Boedeker, E. C., Harpaz, N., & Pace, N. R. (2007) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0706625104 · Cited by 4,611
Recognition of Commensal Microflora by Toll-Like Receptors Is Required for Intestinal Homeostasis
Rakoff-Nahoum, S., Paglino, J., Eslami-Varzaneh, F., Edberg, S., & Medzhitov, R. (2004) · Cell · doi:10.1016/j.cell.2004.07.002 · Cited by 4,251
Tuberculosis Associated with Infliximab, a Tumor Necrosis Factor α–Neutralizing Agent
Keane, J., Gershon, S. K., Wise, R. P., Mirabile‐Levens, E., Kasznica, J. M., Schwieterman, W. D., Siegel, J. N., & Braun, M. M. (2001) · New England Journal of Medicine · doi:10.1056/nejmoa011110 · Cited by 3,683
Transforming growth factor-β induces development of the TH17 lineage
Mangan, P. R., Harrington, L. E., O'Quinn, D. B., Helms, W. S., Bullard, D. C., Elson, C. O., Hatton, R. D., Wahl, S. M., Schoeb, T. R., & Weaver, C. T. (2006) · Nature · doi:10.1038/nature04754 · Cited by 3,087
A Genome-Wide Association Study Identifies IL23R as an Inflammatory Bowel Disease Gene
Duerr, R. H., Taylor, K. D., Brant, S. R., Rioux, J. D., Silverberg, M. S., Daly, M. J., Steinhart, A. H., Abraham, C., Regueiro, M., Griffiths, A., et al. (2006) · Science · doi:10.1126/science.1135245 · Cited by 3,039
Genome-wide association defines more than 30 distinct susceptibility loci for Crohn's disease
the NIDDK IBD Genetics Consortium, Barrett, J. C., the Belgian-French IBD Consortium, the Wellcome Trust Case Control Consortium, Hansoul, S., Nicolae, D. L., Cho, J. H., Duerr, R. H., Rioux, J. D., Brant, S. R., et al. (2008) · Nature Genetics · doi:10.1038/ng.175 · Cited by 2,593
Dendritic cells express tight junction proteins and penetrate gut epithelial monolayers to sample bacteria
Rescigno, M., Urbano, M., Valzasina, B., Francolini, M., Rotta, G., Bonasio, R., Granucci, F., Kraehenbuhl, J.-P., & Ricciardi‐Castagnoli, P. (2001) · Nature Immunology · doi:10.1038/86373 · Cited by 2,554

Show all 104 references

Research works printed but not linked: 6

Musch MW, 2002, J Clin Invest, 110, 1739, 10.1172/JCI0215695 · DOI
Vijay-Kumar M, 2007, J Clin Invest, 117, 3909
10.1172/JCI19229 · DOI
Kamada N, 2008, J Clin Invest, 118, 2269
Watanabe T, 2008, J Clin Invest, 118, 545
Sugimoto K, 2008, J Clin Invest, 118, 534

Sorted by citations

Items 501–600 of 1,008

Influence of Environmental Factors in the Development and Outcomes of Inflammatory Bowel Disease.
Vedamurthy, A., & Ananthakrishnan, A. N. (2019) · Europe PMC (PubMed Central) · Cited by 73
Very Early Onset Inflammatory Bowel Disease Associated with Aberrant Trafficking of IL-10R1 and Cure by T Cell Replete Haploidentical Bone Marrow Transplantation
Murugan, D., Albert, M. H., Langemeier, J., Bohne, J., Puchałka, J., Järvinen, P. M., Hauck, F. H., Klenk, A. K., Prell, C., Schatz, S. B., et al. (2014) · Journal of Clinical Immunology · doi:10.1007/s10875-014-9992-8 · Cited by 72
Activation of the Receptor NKG2D Leads to Production of Th17 Cytokines in CD4+ T Cells of Patients With Crohn's Disease
Pariente, B., Mocan, I., Camus, M., Dutertre, C., Ettersperger, J., Cattan, P., Gornet, J., Dulphy, N., Charron, D. J., Lémann, M., et al. (2011) · Gastroenterology · doi:10.1053/j.gastro.2011.03.061 · Cited by 81
Selenoproteins and oxidative stress-induced inflammatory tumorigenesis in the gut
Barrett, C. W., Short, S. P., & Williams, C. S. (2016) · Cellular and Molecular Life Sciences · doi:10.1007/s00018-016-2339-2 · Cited by 73
Adipose-derived stem cells ameliorate colitis by suppression of inflammasome formation and regulation of M1-macrophage population through prostaglandin E2
Park, H. J., Kim, J., Saima, F. T., Rhee, K., Hwang, S., Kim, M. Y., Baik, S. K., Eom, Y. W., & Kim, H. S. (2018) · Biochemical and Biophysical Research Communications · doi:10.1016/j.bbrc.2018.03.096 · Cited by 72
p-Cymene and Rosmarinic Acid Ameliorate TNBS-Induced Intestinal Inflammation Upkeeping ZO-1 and MUC-2: Role of Antioxidant System and Immunomodulation
Formiga, R. D. O., Júnior, E. B. A., Vasconcelos, R. C., Guerra, G. C. B., de Araújo, A. A., de Carvalho, T. G., Garcia, V. B., Júnior, R. F. D. A., Gadelha, F. A. A. F., Vieira, G. C., et al. (2020) · International Journal of Molecular Sciences · doi:10.3390/ijms21165870 · Cited by 73
Agonist anti-ChemR23 mAb reduces tissue neutrophil accumulation and triggers chronic inflammation resolution
Trilleaud, C., Gauttier, V., Biteau, K., Girault, I., Belarif, L., Mary, C., Pengam, S., Teppaz, G., Thépenier, V., Danger, R., et al. (2021) · Science Advances · doi:10.1126/sciadv.abd1453 · Cited by 74
Development of Spleen Targeting H2S Donor Loaded Liposome for the Effective Systemic Immunomodulation and Treatment of Inflammatory Bowel Disease
Oh, C., Lee, W., Park, J., Choi, J., Lee, S., Li, S., Jung, H. N., Lee, J.-S., Hwang, J.-E., Park, J., et al. (2023) · ACS Nano · doi:10.1021/acsnano.2c08898 · Cited by 73
CCR9 antagonism: potential in the treatment of Inflammatory Bowel Disease
Keshav, S., & Wendt, E. (2015) · Clinical and Experimental Gastroenterology · doi:10.2147/ceg.s48305 · Cited by 76
Environmental Factors in the Relapse and Recurrence of Inflammatory Bowel Disease: A Review of the Literature
Martin, T. D., Chan, S. S. M., & Hart, A. R. (2014) · Digestive Diseases and Sciences · doi:10.1007/s10620-014-3437-3 · Cited by 73
Sphingosine-1-Phosphate Signaling in Inflammatory Bowel Disease
Nielsen, O. H., Li, Y., Johansson‐Lindbom, B., & Coskun, M. (2017) · Trends in Molecular Medicine · doi:10.1016/j.molmed.2017.02.002 · Cited by 76
Clinical and Histologic Mimickers of Celiac Disease
Kamboj, A. K., & Oxentenko, A. S. (2017) · Clinical and Translational Gastroenterology · doi:10.1038/ctg.2017.41 · Cited by 72
The Profile of Human Milk Metabolome, Cytokines, and Antibodies in Inflammatory Bowel Diseases Versus Healthy Mothers, and Potential Impact on the Newborn
Meng, X., Dunsmore, G., Koleva, P. T., Elloumi, Y., Wu, R., Sutton, R. T., Ambrosio, L., Hotte, N., Nguyen, V. V., Madsen, K. L., et al. (2018) · Journal of Crohn s and Colitis · doi:10.1093/ecco-jcc/jjy186 · Cited by 72
Epidemiology of inflammatory bowel disease in South America: A systematic review
Selvaratnam, S., Gullino, S., Shim, L., Lee, E., Lee, A., Paramsothy, S., & Leong, R. W. L. (2019) · World Journal of Gastroenterology · doi:10.3748/wjg.v25.i47.6866 · Cited by 71
Zinc and Selenium in Inflammatory Bowel Disease: Trace Elements with Key Roles?
Vaghari‐Tabari, M., Jafari-Gharabaghlou, D., Sadeghsoltani, F., Hassanpour, P., Qujeq, D., Rashtchizadeh, N., & Ghorbanihaghjo, A. (2020) · Biological Trace Element Research · doi:10.1007/s12011-020-02444-w · Cited by 71
Efficacy and Safety of Mesenchymal Stem/Stromal Cell Therapy for Inflammatory Bowel Diseases: An Up-to-Date Systematic Review
Ko, J. Z.-H., Johnson, S., & Dave, M. (2021) · Biomolecules · doi:10.3390/biom11010082 · Cited by 71
Efficacy of the Punica granatum peels aqueous extract for symptom management in ulcerative colitis patients. A randomized, placebo-controlled, clinical trial
Kamali, M., Tavakoli, H., Khodadoost, M., Daghaghzadeh, H., Kamalinejad, M., Gachkar, L., Mansourian, M., & Adibi, P. (2015) · Complementary Therapies in Clinical Practice · doi:10.1016/j.ctcp.2015.03.001 · Cited by 71
A TNFSF15 disease-risk polymorphism increases pattern-recognition receptor-induced signaling through caspase-8–induced IL-1
Hedl, M., & Abraham, C. (2014) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1404178111 · Cited by 71
Pathogenesis, Diagnosis, and Management of Ulcerative Proctitis, Chronic Radiation Proctopathy, and Diversion Proctitis
Wu, X.-R., Liu, X.-L., Katz, S., & Shen, B. (2014) · Inflammatory Bowel Diseases · doi:10.1097/mib.0000000000000227 · Cited by 71
Dysregulation of T cell receptor N-glycosylation: a molecular mechanism involved in ulcerative colitis
Dias, A. M., Dourado, J., Lago, P. M., Cabral, J., Marcos‐Pinto, R., Salgueiro, P., Almeida, C. R., Carvalho, S., Fonseca, S., Lima, M., et al. (2013) · Human Molecular Genetics · doi:10.1093/hmg/ddt632 · Cited by 72
Compartmentalized Expression of Th1 and Th17 Cytokines in Pediatric Inflammatory Bowel Diseases
Verdier, J., Bègue, B., Cerf–Bensussan, N., & Ruemmele, F. M. (2011) · Inflammatory Bowel Diseases · doi:10.1002/ibd.21905 · Cited by 71
No association of alcohol use and the risk of ulcerative colitis or Crohn’s disease: data from a European Prospective cohort study (EPIC)
Bergmann, M. M., Hernández, V., Bernigau, W., Boeing, H., Chan, S. S. M., Luben, R., Khaw, K., van Schaik, F. D. M., Oldenburg, B., Bueno-de-Mesquita, B. H., et al. (2017) · European Journal of Clinical Nutrition · doi:10.1038/ejcn.2016.271 · Cited by 69
Cannabis, Cannabinoids, and the Endocannabinoid System—Is there Therapeutic Potential for Inflammatory Bowel Disease?
Ambrose, T., & Simmons, A. (2018) · Journal of Crohn s and Colitis · doi:10.1093/ecco-jcc/jjy185 · Cited by 70
Risk of Neurodegenerative Diseases in Patients with Inflammatory Bowel Disease: A Nationwide Population-based Cohort Study
Kim, G. H., Lee, Y. C., Kim, T. J., Kim, E. R., Hong, S. N., Chang, D. K., & Kim, Y. (2021) · Journal of Crohn s and Colitis · doi:10.1093/ecco-jcc/jjab162 · Cited by 72
The Endoplasmic Reticulum Stress Sensor IRE1α in Intestinal Epithelial Cells Is Essential for Protecting against Colitis
Zhang, H.-S., Chen, Y., Fan, L., Xi, Q., Wu, G., Li, X.-X., Yuan, T.-L., He, S.-Q., Yu, Y., Shao, M., et al. (2015) · Journal of Biological Chemistry · doi:10.1074/jbc.m114.633560 · Cited by 74
“A common feature of IBD is the loss of intestinal epithelial barrier function due to excessive epithelial cell death, which allows the invasion of bacteria into the submucosa, leading to inflammatory response and barrier disruption (4).”
Background
Single Nucleotide Polymorphisms That Increase Expression of the Guanosine Triphosphatase RAC1 Are Associated With Ulcerative Colitis
Muise, A. M., Walters, T. D., Xu, W., Shen‐Tu, G., Guo, C., Fattouh, R., Lam, G. Y., Wolters, V. M., Bennitz, J. D., Limbergen, J. V., et al. (2011) · Gastroenterology · doi:10.1053/j.gastro.2011.04.057 · Cited by 72
Faecal microRNA as a biomarker of the activity and prognosis of inflammatory bowel diseases
Ji, Y., Li, X., Zhu, Y., Li, N., Zhang, N.-N., & Niu, M. (2018) · Biochemical and Biophysical Research Communications · doi:10.1016/j.bbrc.2018.06.174 · Cited by 71
Body mass index and risk of inflammatory bowel disease: A systematic review and dose‐response meta‐analysis of cohort studies of over a million participants
Rahmani, J., Kord‐Varkaneh, H., Hekmatdoost, A., Thompson, J., Clark, C. C. T., Salehi‐Sahlabadi, A., Day, A. S., & Jacobson, K. (2019) · Obesity Reviews · doi:10.1111/obr.12875 · Cited by 71
Innate lymphoid cells in inflammatory bowel diseases
Peters, C. P., Mjösberg, J., Bernink, J. H., & Spits, H. (2015) · Immunology Letters · doi:10.1016/j.imlet.2015.10.004 · Cited by 69
Vedolizumab Therapy Is Associated with an Improvement in Sleep Quality and Mood in Inflammatory Bowel Diseases
Stevens, B. W., Borren, N. Z., Velonias, G., Conway, G. M., Cleland, T., Andrews, E., Khalili, H., Garber, J. G., Xavier, R. J., Yajnik, V., et al. (2016) · Digestive Diseases and Sciences · doi:10.1007/s10620-016-4356-2 · Cited by 68
Interventions of natural and synthetic agents in inflammatory bowel disease, modulation of nitric oxide pathways
Kamalian, A., SohrabiAsl, M., Dolatshahi, M., Afshari, K., Shamshiri, S., Roudsari, N. M., Momtaz, S., Rahimi, R., Abdollahi, M. R., & Abdolghaffari, A. H. (2020) · World Journal of Gastroenterology · doi:10.3748/wjg.v26.i24.3365 · Cited by 69
Therapy with stem cells in inflammatory bowel disease
Martínez-Montiel, P. (2014) · World Journal of Gastroenterology · doi:10.3748/wjg.v20.i5.1211 · Cited by 69
Bidirectional Causal Associations Between Inflammatory Bowel Disease and Ankylosing Spondylitis: A Two-Sample Mendelian Randomization Analysis
Cui, Z., Hou, G., Meng, X., Feng, H., He, B., & Tian, Y. (2020) · Frontiers in Genetics · doi:10.3389/fgene.2020.587876 · Cited by 68
“Ulcerative colitis (UC) and Crohn’s disease (CD) are two main forms of inflammatory bowel disease (IBD) (Abraham and Cho, 2009; Ordás et al., 2012; Torres et al., 2012).”
Background
Pivotal role of NOD2 in inflammatory processes affecting atherosclerosis and periodontal bone loss
Yuan, H., Zelkha, S., Burkatovskaya, M., Gupte, R. K., Leeman, S. E., & Amar, S. (2013) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1320862110 · Cited by 68
STAT3 and sphingosine-1-phosphate in inflammation-associated colorectal cancer
Nguyen, A. V. (2014) · World Journal of Gastroenterology · doi:10.3748/wjg.v20.i30.10279 · Cited by 70
Pattern Recognition Receptor Signaling in Human Dendritic Cells is Enhanced by ICOS Ligand and Modulated by the Crohn’s Disease ICOSLG Risk Allele
Hedl, M., Lahiri, A., Ning, K., Cho, J. H., & Abraham, C. (2014) · Immunity · doi:10.1016/j.immuni.2014.04.011 · Cited by 68
The REGγ-proteasome forms a regulatory circuit with IκBɛ and NFκB in experimental colitis
Xu, J., Zhou, L., Ji, L., Chen, F., Fortmann, K. T., Zhang, K., Liu, Q., Li, K., Wang, W., Wang, H., et al. (2016) · Nature Communications · doi:10.1038/ncomms10761 · Cited by 69
Portulaca oleracea extracts and their active compounds ameliorate inflammatory bowel diseases in vitro and in vivo by modulating TNF-α, IL-6 and IL-1β signalling
Kim, Y., Lim, H. J., Jang, H., Lee, S., Jung, K., Lee, S., Lee, S., & Rho, M. (2017) · Food Research International · doi:10.1016/j.foodres.2017.12.058 · Cited by 68
The Intersection of TNF, IBD and the Microbiome
Jones‐Hall, Y., & Nakatsu, C. H. (2016) · Gut Microbes · doi:10.1080/19490976.2015.1121364 · Cited by 68
“As the name implies, UC is confined to the large colon, and results in continuous, superficial ulceration and mucosal inflammation of the colon and/or rectum.(7) Dysregulation of mucosal immunity is a key component of IBD development and progression, with mucosal CD4+ T cells, including T helper (Th)-1, Th-17 and Th-2…”
Background
Novel Therapies and Treatment Strategies for Patients with Inflammatory Bowel Disease
Duijvestein, M., Battat, R. J., Casteele, N. V., D’Haens, G., Sandborn, W. J., Khanna, R., Jairath, V., & Feagan, B. G. (2018) · Current Treatment Options in Gastroenterology · doi:10.1007/s11938-018-0175-1 · Cited by 67
Which long noncoding RNAs and circular RNAs contribute to inflammatory bowel disease?
Lin, L., Zhou, G., Chen, P., Wang, Y., Han, J., Chen, M., He, Y., & Zhang, S. (2020) · Cell Death and Disease · doi:10.1038/s41419-020-2657-z · Cited by 68
The Role of Gut Microbiota and Metabolites in Obesity-Associated Chronic Gastrointestinal Disorders
Islam, M. R., Arthur, S., Haynes, J., Butts, M. R., Nepal, N., & Sundaram, U. (2022) · Nutrients · doi:10.3390/nu14030624 · Cited by 73
Cutaneous Manifestations of Crohn Disease
Hagen, J. W., Swoger, J. M., & Grandinetti, L. M. (2015) · Dermatologic Clinics · doi:10.1016/j.det.2015.03.007 · Cited by 67
Neutralization of Membrane TNF, but Not Soluble TNF, Is Crucial for the Treatment of Experimental Colitis
Perrier, C., Hertogh, G. D., Cremer, J., Vermeire, S., Rutgeerts, P. J., Assche, G. V., Szymkowski, D. E., & Ceuppens, J. L. (2012) · Inflammatory Bowel Diseases · doi:10.1002/ibd.23023 · Cited by 70
Cesarean delivery and risk of inflammatory bowel disease: a systematic review and meta-analysis
Li, Y., Tian, Y., Zhu, W., Gong, J., Gu, L., Zhang, W., Guo, Z., Li, N., & Li, J. (2014) · Scandinavian Journal of Gastroenterology · doi:10.3109/00365521.2014.910834 · Cited by 67
The Immunologic Effects of Mesalamine in Treated HIV-Infected Individuals with Incomplete CD4+ T Cell Recovery: A Randomized Crossover Trial
Somsouk, M., Dunham, R. M., Cohen, M. L., Albright, R. G., Abdel‐Mohsen, M., Liegler, T. J., Lifson, J. D., Piatak, M., Gorelick, R. J., Huang, Y., et al. (2014) · PLoS ONE · doi:10.1371/journal.pone.0116306 · Cited by 67
Integrated Enrichment Analysis of Variants and Pathways in Genome-Wide Association Studies Indicates Central Role for IL-2 Signaling Genes in Type 1 Diabetes, and Cytokine Signaling Genes in Crohn's Disease
Carbonetto, P. S., & Stephens, M. (2013) · PLoS Genetics · doi:10.1371/journal.pgen.1003770 · Cited by 68
Genome-based Definition of an Inflammatory Bowel Disease-associated Adherent-Invasive Escherichia coli Pathovar
Desilets, M., Deng, X., Rao, C., Ensminger, A. W., Krause, D. O., Sherman, P. M., & Gray‐Owen, S. D. (2015) · Inflammatory Bowel Diseases · doi:10.1097/mib.0000000000000574 · Cited by 67
TH17 Cell and Epithelial Cell Crosstalk during Inflammatory Bowel Disease and Carcinogenesis
Kempski, J., Brockmann, L., Gagliani, N., & Huber, S. (2017) · Frontiers in Immunology · doi:10.3389/fimmu.2017.01373 · Cited by 66
Lower Abundance and Impaired Function of CD71+ Erythroid Cells in Inflammatory Bowel Disease Patients During Pregnancy
Dunsmore, G., Koleva, P. T., Ghobakhloo, N., Sutton, R. T., Ambrosio, L., Meng, X., Hotte, N., Nguyen, V. V., Madsen, K. L., Dieleman, L. A., et al. (2018) · Journal of Crohn s and Colitis · doi:10.1093/ecco-jcc/jjy147 · Cited by 67
Mucosal adhesion and anti-inflammatory effects of Lactobacillus rhamnosus GG in the human colonic mucosa: A proof-of-concept study
Pagnini, C., Corleto, V. D., Martorelli, M., Lanini, C., D’Ambra, G., Giulio, E. D., & Fave, G. D. (2018) · World Journal of Gastroenterology · doi:10.3748/wjg.v24.i41.4652 · Cited by 67
Specific accumulation of orally administered redox nanotherapeutics in the inflamed colon reducing inflammation with dose–response efficacy
Vong, L. B., Mo, J., Abrahamsson, B., & Nagasaki, Y. (2015) · Journal of Controlled Release · doi:10.1016/j.jconrel.2015.05.275 · Cited by 67
Early Administration of Infliximab for Severe Ipilimumab-Related Diarrhea in a Critically Ill Patient
Merrill, S. P., Reynolds, P., Kalra, A., Biehl, J., Vandivier, R. W., & Mueller, S. W. (2014) · Annals of Pharmacotherapy · doi:10.1177/1060028014528152 · Cited by 66
“A recent review by Targownik and Bernstein22 addressed the issue of infectious and malignant complications of infliximab in patients with IBD.”
BackgroundInfluential
Blowing on Embers: Commensal Microbiota and Our Immune System
Spasova, D. S., & Surh, C. D. (2014) · Frontiers in Immunology · doi:10.3389/fimmu.2014.00318 · Cited by 72
The Unique Disease Course of Children with Very Early onset-Inflammatory Bowel Disease
Kelsen, J. R., Conrad, M. A., Dawany, N. B., Patel, T., Shraim, R., Merz, A., Maurer, K., Sullivan, K. E., & Devoto, M. (2019) · Inflammatory Bowel Diseases · doi:10.1093/ibd/izz214 · Cited by 68
Role of genetic and environmental factors in British twins with inflammatory bowel disease
Ng, S. C., Woodrow, S. R., Patel, N. B., Subhani, J., & Harbord, M. (2011) · Inflammatory Bowel Diseases · doi:10.1002/ibd.21747 · Cited by 66
Macrophages, Nitric Oxide and microRNAs Are Associated with DNA Damage Response Pathway and Senescence in Inflammatory Bowel Disease
Sohn, J. J., Schetter, A. J., Yfantis, H. G., Ridnour, L. A., Horikawa, I., Ma, K., Robles, A. I., Hussain, S. P., Goto, A., Bowman, E. D., et al. (2012) · PLoS ONE · doi:10.1371/journal.pone.0044156 · Cited by 67
PHD3 Stabilizes the Tight Junction Protein Occludin and Protects Intestinal Epithelial Barrier Function
Chen, Y., Zhang, H.-S., Fong, G., Xi, Q., Wu, G., Bai, C., Ling, Z., Li, F., Xu, Y., Qin, Y.-Q., et al. (2015) · Journal of Biological Chemistry · doi:10.1074/jbc.m115.653584 · Cited by 64
Ascorbic acid ameliorates oxidative stress and inflammation in dextran sulfate sodium-induced ulcerative colitis in mice.
Yan, H., Wang, H., Zhang, X., Li, X., & Yu, J. (2015) · PubMed Central · Cited by 67
The Microbiome in Crohn's Disease
Khanna, S., & Raffals, L. E. (2017) · Gastroenterology Clinics of North America · doi:10.1016/j.gtc.2017.05.004 · Cited by 75
Association between dietary iron and zinc intake and development of ulcerative colitis: A case–control study in Japan
Kobayashi, Y., Ohfuji, S., Kondo, K., Fukushima, W., Sasaki, S., Kamata, N., Yamagami, H., Fujiwara, Y., Suzuki, Y., Hirota, Y., et al. (2019) · Journal of Gastroenterology and Hepatology · doi:10.1111/jgh.14642 · Cited by 66
Ulcerative Colitis Is Characterized by a Decrease in Regulatory B Cells
Wang, X., Zhu, Y., Zhang, M., Wang, H., Jiang, Y., & Gao, P. (2016) · Journal of Crohn s and Colitis · doi:10.1093/ecco-jcc/jjw074 · Cited by 66
Human Gut Dendritic Cells Drive Aberrant Gut-specific T-cell Responses in Ulcerative Colitis, Characterized by Increased IL-4 Production and Loss of IL-22 and IFNγ
Mann, E. R., Bernardo, D., Ng, S. C., Rigby, R. J., Al-Hassi, H. O., Landy, J., Peake, S. T. C., Spranger, H., English, N. R., Thomas, L. V., et al. (2014) · Inflammatory Bowel Diseases · doi:10.1097/mib.0000000000000223 · Cited by 65
Remission of refractory C rohn's disease by high‐dose cyclophosphamide and autologous peripheral blood stem cell transplantation
Hasselblatt, P., Drognitz, K., Potthoff, K., Bertz, H., Kruis, W., Schmidt, C., Stallmach, A., Schmitt-Graeff, A. H., Finke, J., & Kreisel, W. (2012) · Alimentary Pharmacology & Therapeutics · doi:10.1111/apt.12032 · Cited by 65
Medication adherence and persistence in the treatment of Canadian ulcerative colitis patients: analyses with the RAMQ database
Lachaîne, J., Yen, L., Beauchemin, C., & Hodgkins, P. (2013) · BMC Gastroenterology · doi:10.1186/1471-230x-13-23 · Cited by 65
Recent advances in cytokines: Therapeutic implications for inflammatory bowel diseases
Bouguen, G. (2011) · World Journal of Gastroenterology · doi:10.3748/wjg.v17.i5.547 · Cited by 65
Performance of the Montreal classification for inflammatory bowel diseases
Spekhorst, L. M. (2014) · World Journal of Gastroenterology · doi:10.3748/wjg.v20.i41.15374 · Cited by 65
Fostering Inflammatory Bowel Disease: Sphingolipid Strategies to Join Forces
Hadi, L. A., Vito, C. D., & Riboni, L. (2016) · Mediators of Inflammation · doi:10.1155/2016/3827684 · Cited by 66
KIF9‑AS1, LINC01272 and DIO3OS lncRNAs as novel biomarkers for inflammatory bowel disease
Wang, S., Hou, Y., Chen, W., Wang, J., Xie, W., Zhang, X., & Zeng, L. (2017) · Molecular Medicine Reports · doi:10.3892/mmr.2017.8118 · Cited by 65
Overall and Subgroup Prevalence of Crohn Disease Among Patients With Hidradenitis Suppurativa
Garg, A., Hundal, J., & Strunk, A. (2018) · JAMA Dermatology · doi:10.1001/jamadermatol.2018.0878 · Cited by 65
Targeting sirtuin-1 alleviates experimental autoimmune colitis by induction of Foxp3+ T-regulatory cells
Akimova, T., Xiao, H., Liu, Y., Bhatti, T. R., Jiao, J., Eruslanov, E. B., Singhal, S. K., Wang, L., Han, R., Zacharia, K., et al. (2014) · Mucosal Immunology · doi:10.1038/mi.2014.10 · Cited by 67
Misbalance in type III collagen formation/degradation as a novel serological biomarker for penetrating (Montreal B3) Crohn's disease
van Haaften, W. T., Mortensen, J. H., Karsdal, M. A., Bay‐Jensen, A., Dijkstra, G. D. H., & Olinga, P. (2017) · Alimentary Pharmacology & Therapeutics · doi:10.1111/apt.14092 · Cited by 63
The impact of the intestinal microbiome on bone health
Zhang, J., Lu, Y., Wang, Y., Ren, X., & Han, J. (2018) · Intractable & Rare Diseases Research · doi:10.5582/irdr.2018.01055 · Cited by 67
IRGM Variants and Susceptibility to Inflammatory Bowel Disease in the German Population
Glas, J., Seiderer, J., Bues, S., Stallhofer, J., Fries, C., Olszak, T., Tsekeri, E., Wetzke, M., Beigel, F., Steib, C. J., et al. (2013) · PLoS ONE · doi:10.1371/journal.pone.0054338 · Cited by 66
Relevant Infections in Inflammatory Bowel Disease, and Their Relationship With Immunosuppressive Therapy and Their Effects on Disease Mortality
Zabana, Y., Rodríguez, L., Lobatón, T., Gordillo, J., Montserrat, A., Mena, R., Beltrán, B., Dotti, M., Benítez, O., Guardiola, J., et al. (2019) · Journal of Crohn s and Colitis · doi:10.1093/ecco-jcc/jjz013 · Cited by 63
Identifying environmental risk factors for inflammatory bowel diseases: a Mendelian randomization study
Carreras‐Torres, R., Ibáñez‐Sanz, G., Obón‐Santacana, M., Duell, E. J., & Moreno, V. R. (2020) · Scientific Reports · doi:10.1038/s41598-020-76361-2 · Cited by 66
Mesenchymal (Stem) Stromal Cells Based as New Therapeutic Alternative in Inflammatory Bowel Disease: Basic Mechanisms, Experimental and Clinical Evidence, and Challenges
Eiró, N., Fraile, M., González-Jubete, A., González, L. O., & Vizoso, F. J. (2022) · International Journal of Molecular Sciences · doi:10.3390/ijms23168905 · Cited by 63
Increased levels of circulating Th17 cells in quiescent versus active Crohn's disease
Dige, A. K., Støy, S. H., Rasmussen, T. K., Kelsen, J., Hvas, C. L., Sandahl, T. D., Dahlerup, J. F., Deleuran, B. W., & Agnholt, J. S. (2012) · Journal of Crohn s and Colitis · doi:10.1016/j.crohns.2012.06.015 · Cited by 62
IL-22-STAT3 Pathway Plays a Key Role in the Maintenance of Ileal Homeostasis in Mice Lacking Secreted Mucus Barrier
Sovran, B., Loonen, L. M. P., Lü, P., Hugenholtz, F., Belzer, C., Stolte, E. H., Boekschoten, M. V., van Baarlen, P., Kleerebezem, M., de Vos, P., et al. (2015) · Inflammatory Bowel Diseases · doi:10.1097/mib.0000000000000319 · Cited by 62
Differential risk of disease progression between isolated anastomotic ulcers and mild ileal recurrence after ileocolonic resection in patients with Crohn’s disease
Ollech, J. E., Golan, M. A., Weisshof, R., Normatov, I., Sapp, A. R., Kalakonda, A., Israel, A., Glick, L. R., Karrison, T., Dalal, S. R., et al. (2019) · Gastrointestinal Endoscopy · doi:10.1016/j.gie.2019.01.029 · Cited by 63
N-glycans as functional effectors of genetic and epigenetic disease risk
Štambuk, T., Klasić, M., Zoldoš, V., & Lauc, G. (2020) · Molecular Aspects of Medicine · doi:10.1016/j.mam.2020.100891 · Cited by 65
microRNAs: critical regulators in Th17 cells and players in diseases
Wei, B. K., & Pei, G. (2010) · Cellular and Molecular Immunology · doi:10.1038/cmi.2010.19 · Cited by 65
Tumor Necrosis Factor-α-Induced Colitis Increases NADPH Oxidase 1 Expression, Oxidative Stress, and Neutrophil Recruitment in the Colon: Preventive Effect of Apocynin
Mouzaoui, S., Djerdjouri, B., Makhezer, N., Kroviarski, Y., Benna, J. E., & Dang, P. M. (2014) · Mediators of Inflammation · doi:10.1155/2014/312484 · Cited by 66
Screening for modulators of the cellular composition of gut epithelia via organoid models of intestinal stem cell differentiation
Mead, B. E., Hattori, K., Levy, L. E., Imada, S., Goto, N., Vukovic, M., Sze, D., Kummerlowe, C., Matute, J. D., Duan, J., et al. (2022) · Nature Biomedical Engineering · doi:10.1038/s41551-022-00863-9 · Cited by 60
The matricellular protein CCN1 promotes mucosal healing in murine colitis through IL-6
Choi, J. S., Kim, K.-H., & Lau, L. F. (2015) · Mucosal Immunology · doi:10.1038/mi.2015.19 · Cited by 64
Towards personalized care in IBD
Gerich, M. E., & McGovern, D. P. B. (2013) · Nature Reviews Gastroenterology & Hepatology · doi:10.1038/nrgastro.2013.242 · Cited by 63
Early Life Factors and Risk of Inflammatory Bowel Disease in Adulthood
Khalili, H., Ananthakrishnan, A. N., Higuchi, L. M., Richter, J. M., Fuchs, C. S., & Chan, A. T. (2013) · Inflammatory Bowel Diseases · doi:10.1097/mib.0b013e31828132f8 · Cited by 61
Distinct Roles for Nod2 Protein and Autocrine Interleukin-1β in Muramyl Dipeptide-induced Mitogen-activated Protein Kinase Activation and Cytokine Secretion in Human Macrophages
Hedl, M., & Abraham, C. (2011) · Journal of Biological Chemistry · doi:10.1074/jbc.m111.237495 · Cited by 62
Intestinal anti-inflammatory activity of apigenin K in two rat colitis models induced by trinitrobenzenesulfonic acid and dextran sulphate sodium
Mascaraque, C., González, R., Suárez, M. D., Zarzuelo, A., de Medina, F. S., & Martínez‐Augustin, O. (2015) · British Journal Of Nutrition · doi:10.1017/s0007114514004292 · Cited by 62
Inflammatory bowel disease
Boirivant, M., & Cossu, A. (2011) · Oral Diseases · doi:10.1111/j.1601-0825.2011.01811.x · Cited by 65
Randomised clinical trial: a phase 1, dose‐ranging study of the anti‐matrix metalloproteinase‐9 monoclonal antibody GS‐5745 versus placebo for ulcerative colitis
Sandborn, W. J., Bhandari, B. R., Fogel, R., Onken, J. E., Yen, E., Zhao, X., Jiang, Z., Ge, D., Xin, Y., Ye, Z., et al. (2016) · Alimentary Pharmacology & Therapeutics · doi:10.1111/apt.13653 · Cited by 62
Inflammatory bowel disease pathobiology: the role of the interferon signature
Andreou, N.-P. (2020) · Annals of Gastroenterology · doi:10.20524/aog.2020.0457 · Cited by 62
Phenolic Compounds Impact on Rheumatoid Arthritis, Inflammatory Bowel Disease and Microbiota Modulation
Direito, R., Rocha, J. P., Sepodes, B. M. N., & Figueira, M. E. (2021) · Pharmaceutics · doi:10.3390/pharmaceutics13020145 · Cited by 70
Oxidative Stress and Antioxidant Nanotherapeutic Approaches for Inflammatory Bowel Disease
Liu, P., Li, Y., Wang, R., Ren, F., & Wang, X. (2021) · Biomedicines · doi:10.3390/biomedicines10010085 · Cited by 63
Cultivated human intestinal fungus Candida metapsilosis M2006B attenuates colitis by secreting acyclic sesquiterpenoids as FXR agonists
Huo, X., Li, D., Wu, F., Li, S., Qiao, Y., Wang, C., Wang, Y., Zhou, C., Sun, L., Luan, Z., et al. (2022) · Gut · doi:10.1136/gutjnl-2021-325413 · Cited by 61
Research progress of engineered mesenchymal stem cells and their derived exosomes and their application in autoimmune/inflammatory diseases
Zhu, X., Ma, D., Yang, B., An, Q., Zhao, J., Gao, X., & Zhang, L. (2023) · Stem Cell Research & Therapy · doi:10.1186/s13287-023-03295-7 · Cited by 64
Effects of inflammation on bone: an update
Baker-LePain, J. C., Nakamura, M. C., & Lane, N. E. (2011) · Current Opinion in Rheumatology · doi:10.1097/bor.0b013e3283474dbe · Cited by 60
Strong overexpression of CXCR3 axis components in childhood inflammatory bowel disease
Schroepf, S., Kappler, R., Brand, S., Prell, C., Lohse, P., Glas, J., Hoster, E., Helmbrecht, J., Ballauff, A., Berger, M., et al. (2010) · Inflammatory Bowel Diseases · doi:10.1002/ibd.21312 · Cited by 61
The association of minocycline and the probiotic Escherichia coli Nissle 1917 results in an additive beneficial effect in a DSS model of reactivated colitis in mice
Garrido‐Mesa, N., Utrilla, P., Comalada, M., Zorrilla, P., Garrido‐Mesa, J., Zarzuelo, A., Rodríguez‐Cabezas, M. E., & Gálvez, J. (2011) · Biochemical Pharmacology · doi:10.1016/j.bcp.2011.09.004 · Cited by 62
The IL18RAP Region Disease Polymorphism Decreases IL-18RAP/IL-18R1/IL-1R1 Expression and Signaling through Innate Receptor–Initiated Pathways
Hedl, M., Zheng, S., & Abraham, C. (2014) · The Journal of Immunology · doi:10.4049/jimmunol.1302727 · Cited by 61

Authors: Abraham, C., & Cho, J. H.
Affiliations: Yale University (US)
ORCID: Abraham, Clara
Cho, Judy H.
Venue: New England Journal of Medicine
Publisher: Massachusetts Medical Society
Published: 2009-11-19
Volume: 361
Issue: 21
Pages: 2066-2078
ISSN: 0028-4793 (ISSN-L)
1533-4406
DOI: 10.1056/nejmra0804647
PMC: PMC3491806
OpenAlex: W4244626580
Cited by: 2,712
References: 104
Citations by year: 2026: 94 · 2025: 137 · 2024: 169 · 2023: 151 · 2022: 171 · 2021: 184 · 2020: 237 · 2019: 189 · 2018: 193 · 2017: 182 · 2016: 171 · 2015: 217 · 2014: 174 · 2013: 142 · 2012: 120
FWCI: 9.21
Type: journal article
Language: en
Open access: bronze
doi.org
Locations: New England Journal of Medicine (publishedVersion)
PubMed (publishedVersion)
Europe PMC (PubMed Central) (acceptedVersion)
PubMed Central (acceptedVersion)
Funders: Crohn's and Colitis Foundation of America (DK062422, R01DK077905)
Crohn's and Colitis Foundation
National Institutes of Health (DK P30-34989, U01 DK62429)
Takeda Oncology
National Institute of Diabetes and Digestive and Kidney Diseases (DK P30 34989, U01-DK62429, R01DK072373, R01DK077905, RC1DK086800, U01DK062429, P30DK034989, U01DK062422)
National Center for Research Resources (UL1RR024139)
Topics: Health Sciences › Medicine › Gastroenterology › Inflammatory Bowel Disease
Health Sciences › Medicine › Ophthalmology › Ocular Diseases and Behçet’s Syndrome
Health Sciences › Medicine › Dermatology › Autoimmune and Inflammatory Disorders
Keywords: inflammatory bowel disease
MeSH terms: Animals, Colitis, Ulcerative, Crohn Disease, Humans, Immunity, Innate, Intestinal Mucosa, T-Lymphocytes, Inflammatory Bowel Diseases, Interleukin-23, Metagenome

About these checks

Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.

Statistics and arithmetic are recomputed, not judged.

Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.

What counts as a claim ›How we measure confidence ›How we check this ›

Are you an author, or do you see a problem with this page? Request a review

Inflammatory Bowel Disease

Abstract

Overview

Integrity signals

Verification

Claims the paper makes

Claims other papers make about this one

Self-check

Citations

Cites

Cited by

Related

Metadata

Record

About these checks