Cited by 2,712Inflammatory Bowel DiseaseOcular Diseases and Behçet’s SyndromeAutoimmune and Inflammatory Disorders

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Inflammatory Bowel Disease

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Abraham, Clara, Cho, Judy H.·2009·New England Journal of Medicine

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“The impact of the disease on patient quality of life is substantial due to its onset in young adulthood, fluctuating periods in which the disease is active (relapse and remission) and the lack of a cure (Abraham and Cho, 2009).”
Background
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Early postoperative complications in patients with Crohn's disease given and not given preoperative total parenteral nutrition
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Protective role of the leukotriene B 4 receptor BLT2 in murine inflammatory colitis
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Demographic and Clinical Predictors of High Healthcare Use in Patients with Inflammatory Bowel Disease
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Influence of environmental factors in the development of inflammatory bowel diseases
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Fecal transplantation for treatment of inflammatory bowel disease
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The Genetics of Inflammatory Bowel Disease
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Experimental colitis models: Insights into the pathogenesis of inflammatory bowel disease and translational issues
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“defective epithelial barrier and under the influence of various environmental triggers.(Abraham and Cho, 2009) A significant amount of data to support this hypothesis has been generated by studies in experimental models of intestinal inflammation.”
Result
CD39 and CD161 Modulate Th17 Responses in Crohn's Disease
Bai, A., Moss, A. C., Kokkotou, E. G., Usheva, A., Sun, X., Cheifetz, A. S., Zheng, Y., Longhi, M. S., Gao, W., Wu, Y., et al. (2014) · The Journal of Immunology · doi:10.4049/jimmunol.1400346 · Cited by 92
Interleukin-15 promotes intestinal dysbiosis with butyrate deficiency associated with increased susceptibility to colitis
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Authors: Abraham, C., & Cho, J. H.
Affiliations: Yale University (US)
ORCID: Abraham, Clara
Cho, Judy H.
Venue: New England Journal of Medicine
Publisher: Massachusetts Medical Society
Published: 2009-11-19
Volume: 361
Issue: 21
Pages: 2066-2078
ISSN: 0028-4793 (ISSN-L)
1533-4406
DOI: 10.1056/nejmra0804647
PMC: PMC3491806
OpenAlex: W4244626580
Cited by: 2,712
References: 104
Citations by year: 2026: 94 · 2025: 137 · 2024: 169 · 2023: 151 · 2022: 171 · 2021: 184 · 2020: 237 · 2019: 189 · 2018: 193 · 2017: 182 · 2016: 171 · 2015: 217 · 2014: 174 · 2013: 142 · 2012: 120
FWCI: 9.21
Type: journal article
Language: en
Open access: bronze
doi.org
Locations: New England Journal of Medicine (publishedVersion)
PubMed (publishedVersion)
Europe PMC (PubMed Central) (acceptedVersion)
PubMed Central (acceptedVersion)
Funders: Crohn's and Colitis Foundation of America (DK062422, R01DK077905)
Crohn's and Colitis Foundation
National Institutes of Health (DK P30-34989, U01 DK62429)
Takeda Oncology
National Institute of Diabetes and Digestive and Kidney Diseases (DK P30 34989, U01-DK62429, R01DK072373, R01DK077905, RC1DK086800, U01DK062429, P30DK034989, U01DK062422)
National Center for Research Resources (UL1RR024139)
Topics: Health Sciences › Medicine › Gastroenterology › Inflammatory Bowel Disease
Health Sciences › Medicine › Ophthalmology › Ocular Diseases and Behçet’s Syndrome
Health Sciences › Medicine › Dermatology › Autoimmune and Inflammatory Disorders
Keywords: inflammatory bowel disease
MeSH terms: Animals, Colitis, Ulcerative, Crohn Disease, Humans, Immunity, Innate, Intestinal Mucosa, T-Lymphocytes, Inflammatory Bowel Diseases, Interleukin-23, Metagenome

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