Circadian Mechanisms in Medicine

Obesity and Metabolic Syndrome in Circadian Clock Mutant Mice

Turek, F. W., Joshu, C., Kohsaka, A., Lin, E., Ivanova, G., McDearmon, E., Laposky, A., Losee-Olson, S., Easton, A., Jensen, D. R., et al. (2005) · Science · doi:10.1126/science.1108750 · Cited by 2,485

Coordinated Transcription of Key Pathways in the Mouse by the Circadian Clock

Panda, S., Antoch, M. P., Miller, B. H., Su, A. I., Schook, A. C., Straume, M., Schultz, P. G., Kay, S. A., Takahashi, J. S., & Hogenesch, J. B. (2002) · Cell · doi:10.1016/s0092-8674(02)00722-5 · Cited by 2,310

A circadian gene expression atlas in mammals: Implications for biology and medicine

Zhang, R., Lahens, N. F., Ballance, H. I., Hughes, M. E., & Hogenesch, J. B. (2014) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1408886111 · Cited by 2,304

Clock Mutants of Drosophila melanogaster

Konopka, R. J., & Benzer, S. (1971) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.68.9.2112 · Cited by 2,287

A Serum Shock Induces Circadian Gene Expression in Mammalian Tissue Culture Cells

Balsalobre, A., Damiola, F., & Schibler, U. (1998) · Cell · doi:10.1016/s0092-8674(00)81199-x · Cited by 2,001

Time-restricted feeding without reducing caloric intake prevents metabolic diseases in mice fed a high-fat diet

Hatori, M., Vollmers, C., Zarrinpar, A., DiTacchio, L., Bushong, E. A., Gill, S., Leblanc, M., Chaix, A., Joens, M., Fitzpatrick, J. A. J., et al. (2012) · Cell Metabolism · doi:10.1016/j.cmet.2012.04.019 · Cited by 1,986

Circadian Variation in the Frequency of Onset of Acute Myocardial Infarction

Muller, J. E., Stone, P. H., Turi, Z. G., Rutherford, J. D., Czeisler, C. A., Parker, C., Poole, W. K., Passamani, E., Roberts, R., Robertson, T., et al. (1985) · New England Journal of Medicine · doi:10.1056/nejm198511213132103 · Cited by 1,884

Transplanted Suprachiasmatic Nucleus Determines Circadian Period

Ralph, M. R., Foster, R. G., Davis, F. C., & Menaker, M. (1990) · Science · doi:10.1126/science.2305266 · Cited by 1,853

High-Fat Diet Disrupts Behavioral and Molecular Circadian Rhythms in Mice

Kohsaka, A., Laposky, A. D., Ramsey, K. M., Estrada, C., Joshu, C., Kobayashi, Y., Turek, F. W., & Bass, J. (2007) · Cell Metabolism · doi:10.1016/j.cmet.2007.09.006 · Cited by 1,528

Transcriptional architecture and chromatin landscape of the core circadian clock in mammals

Koike, N., Yoo, S.-H., Huang, H.-C., Kumar, V., Lee, C., Kim, T.-K., & Takahashi, J. S. (2012) · Science · doi:10.1126/science.1226339 · Cited by 1,464

Circadian disruption reduces MUC4 expression via the clock molecule BMAL1 during dry eye development

Zeng, H., Yang, X., Liao, K., Zuo, X., Liang, L., He, D., Ju, R., Wang, B., & Yuan, J. (2024) · Experimental & Molecular Medicine · doi:10.1038/s12276-024-01269-0 · Cited by 24

Prolonged dual hypothermic oxygenated machine preservation (DHOPE-PRO) in liver transplantation: study protocol for a stage 2, prospective, dual-arm, safety and feasibility clinical trial

Brüggenwirth, I. M. A., Lantinga, V. A., Rayar, M., van den Berg, A. P., Blokzijl, H., Reyntjens, K. M. E. M., Porte, R. J., & de Meijer, V. E. (2022) · BMJ Open Gastroenterology · doi:10.1136/bmjgast-2021-000842 · Cited by 24

Inter-layer and inter-subject variability of diurnal gene expression in human skin

del Olmo, M., Spörl, F., Korge, S., Jürchott, K., Felten, M., Grudziecki, A., de Zeeuw, J., Nowozin, C., Reuter, H., Blatt, T., et al. (2022) · NAR Genomics and Bioinformatics · doi:10.1093/nargab/lqac097 · Cited by 24

Content Validation of a Chrononutrition Questionnaire for the General and Shift Work Populations: A Delphi Study

Phoi, Y. Y., Bonham, M. P., Rogers, M., Dorrian, J., & Coates, A. M. (2021) · Nutrients · doi:10.3390/nu13114087 · Cited by 26

Daytime Lipid Metabolism Modulated by CLOCK Gene Is Linked to Retinal Ganglion Cells Damage in Glaucoma

Gubin, D. G., Neroev, V. V., Malishevskaya, Т. N., Kolomeichuk, S. N., Weinert, D., Yuzhakova, N., Nelaeva, A. A., Filippova, Y., & Cornélissen, G. (2022) · Applied Sciences · doi:10.3390/app12136374 · Cited by 23

Circadian rhythms and the liver

Costa, R., Mangini, C., Domenie, E. D., Zarantonello, L., & Montagnese, S. (2023) · Liver International · doi:10.1111/liv.15501 · Cited by 23

Пос ттравматичний стресовий розлад, метаболічний синдром і вег етативна нервова система

Serhiyenko, V. A., Sehin, V. B., Serhiyenko, L. M., & Serhiyenko, A. A. (2023) · Endokrynologia · doi:10.31793/1680-1466.2023.28-4.377 · Cited by 23

Social jetlag and depressive symptoms among young people: a systematic review and meta-analysis

Sun, S., Yang, Y., Yu, F., He, Y., Luo, C., Zhang, M., Chen, H., & Tung, T. (2025) · BMC Psychiatry · doi:10.1186/s12888-025-07066-x · Cited by 27

Cell state dependent effects of Bmal1 on melanoma immunity and tumorigenicity

Zhang, X., Pant, S. M., Ritch, C. C., Tang, H., Shao, H., Dweep, H., Gong, Y.-Y., Brooks, R. C., Brafford, P. A., Wolpaw, A. J., et al. (2024) · Nature Communications · doi:10.1038/s41467-024-44778-2 · Cited by 23

The missing hallmark of health: psychosocial adaptation

López-Otín, C., & Kroemer, G. (2024) · Cell Stress · doi:10.15698/cst2024.03.294 · Cited by 27

Higher central circadian temperature amplitude is associated with greater metabolite rhythmicity in humans

Windred, D. P., Anderson, C., Jeppe, K. J., Ftouni, S., Grant, L. K., Nijagal, B., Rajaratnam, S. M. W., McConville, M. J., Tull, D., Lockley, S. W., et al. (2024) · Scientific Reports · doi:10.1038/s41598-024-67297-y · Cited by 21

Circadian Influences on Brain Lipid Metabolism and Neurodegenerative Diseases

Hussain, Y., Dar, M. I., & Pan, X. (2024) · Metabolites · doi:10.3390/metabo14120723 · Cited by 23

PER2 interaction with HSP70 promotes cuproptosis in oral squamous carcinoma cells by decreasing AKT stability

Yu, W., Yin, S., Tang, H., Li, H., Zhang, Z., & Yang, K. (2025) · Cell Death and Disease · doi:10.1038/s41419-025-07523-1 · Cited by 25

Associations between light at night and mental health: A systematic review and meta-analysis

Deprato, A., Haldar, P., Navarro, J. F., Harding, B. N., Lacy, P., Maidstone, R. J., Moitra, S., Cros, A. P., Durrington, H. J., Kogevinas, M., et al. (2025) · The Science of The Total Environment · doi:10.1016/j.scitotenv.2025.179188 · Cited by 26

The Chronobiology of Hormone Administration: “Doctor, What Time Should I Take My Medication?”

Colonnello, E., Graziani, A., Rossetti, R., Voltan, G., Masi, D., Lubrano, C., Mariani, S., Watanabe, M., Isidori, A. M., Ferlin, A., et al. (2025) · Endocrine Reviews · doi:10.1210/endrev/bnaf013 · Cited by 24

Circadian clock gene BMAL1 inhibits the proliferation and tumor-formation ability of nasopharyngeal carcinoma cells and increases the sensitivity of radiotherapy

Zhao, C., Meng, X., Li, Y., Liu, L., He, Q., Jiang, J., Chen, Y., Li, X., Li, Y., Tang, Y., et al. (2022) · Chronobiology International · doi:10.1080/07420528.2022.2105708 · Cited by 21

Type 2 diabetes disrupts circadian orchestration of lipid metabolism and membrane fluidity in human pancreatic islets

Petrenko, V., Sinturel, F., Loizides‐Mangold, U., Montoya, J. P., Chera, S., Riezman, H., & Dibner, C. (2022) · PLoS Biology · doi:10.1371/journal.pbio.3001725 · Cited by 23

Cyclic uniaxial mechanical load enhances chondrogenesis through entraining the molecular circadian clock

Vágó, J., Katona, É., Takács, R., Dócs, K., Hajdú, T., Kovács, P., Zákány, R., van der Veen, D. R., & Matta, C. (2022) · Journal of Pineal Research · doi:10.1111/jpi.12827 · Cited by 21

Identifying Modifiable Predictors of COVID-19 Vaccine Side Effects: A Machine Learning Approach

Abbaspour, S., Robbins, G. K., Blumenthal, K. G., Hashimoto, D. M., Hopcia, K. L., Mukerji, S. S., Shenoy, E. S., Wang, W., & Klerman, E. B. (2022) · Vaccines · doi:10.3390/vaccines10101747 · Cited by 21

Unfavorable Mealtime, Meal Skipping, and Shiftwork Are Associated with Circadian Syndrome in Adults Participating in NHANES 2005–2016

Akbar, Z., & Shi, Z. (2024) · Nutrients · doi:10.3390/nu16111581 · Cited by 23

Effect of Smartphone Use on Sleep in Undergraduate Medical Students: A Cross-Sectional Study

Goel, A., Moinuddin, A., Tiwari, R., Sethi, Y., Suhail, M. K., Mohan, A., Kaka, N., Sarthi, P., Dutt, R., Ahmad, S. F., et al. (2023) · Healthcare · doi:10.3390/healthcare11212891 · Cited by 27

The role of circadian clock pathways in viral replication

Zhuang, X. A., Edgar, R. S., & McKeating, J. A. (2022) · Seminars in Immunopathology · doi:10.1007/s00281-021-00908-2 · Cited by 20

Circadian Rhythm Dysregulation and Leukemia Development: The Role of Clock Genes as Promising Biomarkers

Sanford, A. B. A., da Cunha, L. S., Machado, C. B., Pessoa, F. M. C. D. P., Silva, A. N. D. S., Ribeiro, R. M., Moreira, F. C., de Moraes, M. O., de Moraes, M. E. A., de Souza, L. E. B., et al. (2022) · International Journal of Molecular Sciences · doi:10.3390/ijms23158212 · Cited by 21

Uncovering the Novel Role of NR1D1 in Regulating BNIP3-Mediated Mitophagy in Ulcerative Colitis

Chen, Y., Li, J., Li, S., Cheng, Y., Fu, X., Li, J., & Zhu, L. (2023) · International Journal of Molecular Sciences · doi:10.3390/ijms241814222 · Cited by 20

Influence of light at night on allergic diseases: a systematic review and meta-analysis

Deprato, A., Maidstone, R. J., Cros, A. P., Adán, A., Haldar, P., Harding, B. N., Lacy, P., Melenka, L., Moitra, S., Navarro, J. F., et al. (2024) · BMC Medicine · doi:10.1186/s12916-024-03291-5 · Cited by 22

Role of the circadian nuclear receptor REV-ERBα in dorsal raphe serotonin synthesis in mood regulation

Park, I., Choi, M., Kim, J., Jang, S., Kim, D., Kim, J., Choe, Y., Geum, D., Yu, S.-W., Choi, J., et al. (2024) · Communications Biology · doi:10.1038/s42003-024-06647-y · Cited by 20

Melatonin refines ovarian mitochondrial dysfunction in PCOS by regulating the circadian rhythm gene Clock

Chen, W., Zhang, H., Guo, B., Tao, Y., Zhang, J., Wang, J., Chen, G., Cheng, M., Hong, Q., Cao, Y., et al. (2025) · Cellular and Molecular Life Sciences · doi:10.1007/s00018-025-05609-9 · Cited by 19

Identification of novel small molecules targeting core clock proteins to regulate circadian rhythm

Kavaklı, İ. H., Gül, Ş., & Türkay, M. (2021) · Current Opinion in Chemical Engineering · doi:10.1016/j.coche.2021.100730 · Cited by 18

Caffeine Therapy for Apnea of Prematurity: Role of the Circadian CLOCK Gene Polymorphism

Guo, H., Long, J., Hu, Y., Liu, Y., He, X., Li, L., Xia, Y., Ding, X., Chen, F., Xu, J., et al. (2022) · Frontiers in Pharmacology · doi:10.3389/fphar.2021.724145 · Cited by 20

Therapeutic Implications of Probiotics in the Gut Microbe-Modulated Neuroinflammation and Progression of Alzheimer’s Disease

Murai, T., & Matsuda, S. (2023) · Life · doi:10.3390/life13071466 · Cited by 20

The circadian clock at the intersection of metabolism and aging – emerging roles of metabolites

Dong, Y., Lam, S. M., Li, Y., Li, M., & Shui, G. (2025) · Journal of genetics and genomics/Journal of Genetics and Genomics · doi:10.1016/j.jgg.2025.04.014 · Cited by 22

Chronothyroidology: Chronobiological Aspects in Thyroid Function and Diseases

Bellastella, G., Maiorino, M. I., Scappaticcio, L., Bellis, A. D., Mercadante, S., Esposito, K., & Bellastella, A. (2021) · Life · doi:10.3390/life11050426 · Cited by 18

Screen use before sleep and emotional problems among adolescents: Preliminary evidence of mediating effect of chronotype and social jetlag

Yue, L., Cui, N., Li, J., & Cui, N. (2023) · Journal of Affective Disorders · doi:10.1016/j.jad.2023.02.049 · Cited by 18

Association of sleep complaints with all-cause and heart disease mortality among US adults

Wang, Q., Hu, S., Pan, N., Zhang, T., Ren, L., & Wang, Y. (2023) · Frontiers in Public Health · doi:10.3389/fpubh.2023.1043347 · Cited by 17

Shift work and evening chronotype are associated with hepatic fat fraction and non-alcoholic fatty liver disease in 282,303 UK biobank participants

Maidstone, R. J., Rutter, M. K., Marjot, T., Ray, D. W., & Baxter, M. D. (2023) · Endocrine Connections · doi:10.1530/ec-23-0472 · Cited by 21

Crosstalk between Circadian Rhythm Dysregulation and Tumorigenesis, Tumor Metabolism and Tumor Immune Response

Zhu, Y., Zheng, Y., Dai, R., & Gu, X. (2024) · Aging and Disease · doi:10.14336/ad.2024.0533 · Cited by 22

Role of ketones, ketogenic diets and intermittent fasting in ICU

Gunst, J., Casaer, M. P., Langouche, L., & den Berghe, G. V. (2021) · Current Opinion in Critical Care · doi:10.1097/mcc.0000000000000841 · Cited by 19

Stem Cell Theory of Cancer: Implications for Drug Resistance and Chemosensitivity in Cancer Care

Tu, S., Guo, C. C., Chow, D. S., & Zacharias, N. M. (2022) · Cancers · doi:10.3390/cancers14061548 · Cited by 18

The Effect of Light on Wellbeing: A Systematic Review and Meta-analysis

Landvreugd, A., Nivard, M. G., & Bartels, M. (2024) · Journal of Happiness Studies · doi:10.1007/s10902-024-00838-4 · Cited by 21

Circadian disruption by simulated shift work aggravates periodontitis via orchestrating BMAL1 and GSDMD-mediated pyroptosis

Wang, Y. Z., Li, R., Ye, Q., Fei, D., Zhang, X., Huang, J., Liu, T., Wang, J., & Wang, Q. (2025) · International Journal of Oral Science · doi:10.1038/s41368-024-00331-x · Cited by 20

Circadian clock genes and insomnia: molecular mechanisms and therapeutic implications

Ren, Q., Gu, M., & Xu, F. (2025) · Annals of Medicine · doi:10.1080/07853890.2025.2576643 · Cited by 22

Precision caffeine therapy for apnea of prematurity and circadian rhythms: New possibilities open up

Dai, H., Guo, H., Hu, Y., Xu, J., Ding, X., Cheng, R., & Chen, F. (2022) · Frontiers in Pharmacology · doi:10.3389/fphar.2022.1053210 · Cited by 18

Data integration and analysis for circadian medicine

Baum, L., Johns, M., Poikela, M. E., Möller, R., Ananthasubramaniam, B., & Praßer, F. (2023) · Acta Physiologica · doi:10.1111/apha.13951 · Cited by 21

The circadian clock CRY1 regulates pluripotent stem cell identity and somatic cell reprogramming

Sato, S., Hishida, T., Kinouchi, K., Hatanaka, F., Li, Y., Nguyen, Q., Chen, Y., Wang, P. H., Kessenbrock, K., Li, W., et al. (2023) · Cell Reports · doi:10.1016/j.celrep.2023.112590 · Cited by 22

Circadian regulation of pulmonary disease: the importance of timing

Cunningham, P. S., Jackson, C., Chakraborty, A., Cain, J., Durrington, H. J., & Blaikley, J. (2023) · Clinical Science · doi:10.1042/cs20220061 · Cited by 16

Sleep Disorders: Pathogenesis and Therapeutic Interventions

Liu, C., He, Z., Wu, Y., Liu, Y., Li, Z., Jia, Y., & Xiang, H. (2025) · MedComm · doi:10.1002/mco2.70130 · Cited by 19

Biological Clock and Inflammatory Bowel Disease Review: From the Standpoint of the Intestinal Barrier

Tian, Y., & Zhang, D. (2022) · Gastroenterology Research and Practice · doi:10.1155/2022/2939921 · Cited by 17

Prognostication in Advanced Cancer by Combining Actigraphy-Derived Rest-Activity and Sleep Parameters with Routine Clinical Data: An Exploratory Machine Learning Study

Patel, S. D., Davies, A. N., Laing, E., Wu, H., Mendis, J. R., & Dijk, D. (2023) · Cancers · doi:10.3390/cancers15020503 · Cited by 16

Does circadian dysrhythmia drive the switch into high‐ or low‐activation states in bipolar I disorder?

Hickie, I. B., Merikangas, K. R., Carpenter, J. S., Iorfino, F., Scott, E. M., Scott, J. L., & Crouse, J. J. (2023) · Bipolar Disorders · doi:10.1111/bdi.13304 · Cited by 16

Inverse Relationship Between Clock Gene Expression and Inflammatory Markers in Ulcerative Colitis Patients Undergoing Remission

Weintraub, Y., Cohen, S., Anafy, A., Chapnik, N., Tsameret, S., Ben‐Tov, A., Yerushalmy‐Feler, A., Dotan, I., Tauman, R., & Froy, O. (2023) · Digestive Diseases and Sciences · doi:10.1007/s10620-023-07847-y · Cited by 16

BMAL1-TTK-H2Bub1 loop deficiency contributes to impaired BM-MSC-mediated bone formation in senile osteoporosis

Li, J., Peitao, X., Wenhui, Y., Ye, G., Feng, Y., Xu, X., Su, Z., Lin, J., Yunshu, C., Zhaoqiang, Z., et al. (2023) · Molecular Therapy — Nucleic Acids · doi:10.1016/j.omtn.2023.02.014 · Cited by 16

Circadian rhythm of plasminogen activator inhibitor-1 and cardiovascular complications in type 2 diabetes

Yu, Y., Li, W., Xu, L., & Wang, Y. (2023) · Frontiers in Endocrinology · doi:10.3389/fendo.2023.1124353 · Cited by 16

Biological clock regulation by the PER gene family: a new perspective on tumor development

Chen, K., Wang, Y., Li, D., Wu, R., Wang, J., Wei, W., Zhu, W., Xie, W., Feng, D., & He, Y. (2024) · Frontiers in Cell and Developmental Biology · doi:10.3389/fcell.2024.1332506 · Cited by 16

The dark side of apnea: altered 24-hour melatonin secretion in obstructive sleep apnea (OSAS) is disease severity dependent

Karel, P., Schilperoord, M., Reichman, L. J. A., & Krabbe, J. G. (2024) · Sleep And Breathing · doi:10.1007/s11325-024-03066-5 · Cited by 16

Review: Circadian clocks and rhythms in the vascular tree

Han, Q., Bagi, Z. A., & Rudic, R. D. (2021) · Current Opinion in Pharmacology · doi:10.1016/j.coph.2021.04.010 · Cited by 17

The circadian clock, metabolism, and inflammation—the holy trinity of inflammatory bowel diseases

Froy, O., & Weintraub, Y. (2025) · Clinical Science · doi:10.1042/cs20256383 · Cited by 18

Chronobiology of transient global amnesia

Hoyer, C., Higashida, K., Fabbian, F., Giorgi, A. D., Sandikci, V., Ebert, A., Platten, M., Okazaki, S., Manfredini, R., & Szabo, K. (2021) · Journal of Neurology · doi:10.1007/s00415-021-10639-x · Cited by 15

Gut microbial methionine impacts circadian clock gene expression and reactive oxygen species level in host gastrointestinal tract

Liu, X., Ma, Y., Yu, Y., Zhang, W., Shi, J., Zhang, X., Dai, M., Wang, Y., Zhang, H., Zhang, J., et al. (2022) · Protein & Cell · doi:10.1093/procel/pwac021 · Cited by 15

Researchers need to better address time-of-day as a critical biological variable

Nelson, R. J., DeVries, A. C., & Prendergast, B. J. (2024) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.2316959121 · Cited by 15

Cell-Associated Human Immunodeficiency Virus (HIV) Ribonucleic Acid Has a Circadian Cycle in Males With HIV on Antiretroviral Therapy

Stern, J., Solomon, A. E., Dantanarayana, A., Pascoe, R. D., Reynaldi, A., Davenport, M. P., Milush, J. M., Deeks, S. G., Hartogensis, W., Hecht, F. M., et al. (2021) · The Journal of Infectious Diseases · doi:10.1093/infdis/jiab533 · Cited by 15

Perspectives: on Precision Nutrition Research in Heart, Lung, and Blood Diseases and Sleep Disorders

PRATT, C. A., Brown, A. G. M., Dixit, S., Farmer, N. M., Natarajan, A. R., Boyington, J., Shi, S., Lu, Q., & Cotton, P. A. (2022) · Advances in Nutrition · doi:10.1093/advances/nmac053 · Cited by 15

Circadian Mechanisms in Medicine

Lin, H. Y.-H., Yang, M.-Y., & Lin, S.-F. (2021) · New England Journal of Medicine · doi:10.1056/nejmc2104154 · Cited by 19

Association between polarity of first episode and solar insolation in bipolar I disorder

Bauer, M., Glenn, T., Achtyes, E. D., Alda, M., Agaoglu, E., Altınbaş, K., Andreassen, O. A., Angelopoulos, E., Ardau, R., Aydin, M., et al. (2022) · Journal of Psychosomatic Research · doi:10.1016/j.jpsychores.2022.110982 · Cited by 14

A CRISPR-Customizable Copper-Coordinated DNA Nanoplatform Potentiates Cuproptosis Through Circadian and Metabolic Pathway Manipulation

Zhang, W., Feng, Z., Feng, Z., Lian, R., Liu, Z., & Zhang, J. (2025) · ACS Nano · doi:10.1021/acsnano.5c12641 · Cited by 16

Circadian system and aging: where both times interact

Cobarro, C., Soares, L. I., Kutsenko, Y., & Tomás‐Loba, A. (2025) · Frontiers in Aging · doi:10.3389/fragi.2025.1646794 · Cited by 15

Circadian signatures of adipose tissue in diet-induced obesity

Xin, H., Zhang, J., Huang, R., Li, L., Lam, S. M., Shui, G., Deng, F., Zhang, Z., & Li, M. (2022) · Frontiers in Physiology · doi:10.3389/fphys.2022.953237 · Cited by 14

Circadian orchestration of host and gut microbiota in infection

Xia, Y., Ding, X., Wang, S., & Ren, W. (2022) · Biological reviews/Biological reviews of the Cambridge Philosophical Society · doi:10.1111/brv.12898 · Cited by 16

Sleep irregularity and the association with hypertension and blood pressure levels: the ELSA-Brasil study

Parise, B. K., Santos, R. B., Mesas, A. E., Silva, W. A., Giatti, S., Aielo, A. N., da Cunha, L. F., Souza, S. P., Bortolotto, L. A., Griep, R. H., et al. (2023) · Journal of Hypertension · doi:10.1097/hjh.0000000000003392 · Cited by 14

Conserved and Unique Roles of bHLH-PAS Transcription Factors in Insects – From Clock to Hormone Reception

Tumova, S., Doležel, D., & Jindra, M. (2023) · Journal of Molecular Biology · doi:10.1016/j.jmb.2023.168332 · Cited by 15

Managing Circadian Disruption due to Hospitalization: A Pilot Randomized Controlled Trial of the CircadianCare Inpatient Management System

Mangini, C., Zarantonello, L., Formentin, C., Giusti, G., Domenie, E. D., Ruggerini, D., Costa, R., Skene, D. J., Basso, D., Battagliarin, L., et al. (2023) · Journal of Biological Rhythms · doi:10.1177/07487304231213916 · Cited by 14

The circadian clock orchestrates spermatogonial differentiation and fertilization by regulating retinoic acid signaling in vertebrates

Liu, T., He, W., Zhong, Z., Lü, C., Wu, L., Wang, Z., Smith, W. K., Shi, Q., Long, Q., & Wang, H. (2024) · National Science Review · doi:10.1093/nsr/nwae456 · Cited by 14

The prognostic impact of daytime and seasonality of radiotherapy on head and neck cancer

Eliçin, O., Brolese, E. K., Bojaxhiu, B., Sermaxhaj, B., Schanne, D. H., Mathier, E., Lippmann, J., Shelan, M., Eller, Y. G., Aebersold, D. M., et al. (2021) · Radiotherapy and Oncology · doi:10.1016/j.radonc.2021.04.004 · Cited by 14

The neurophysiologic basis of the human sleep–wake cycle and the physiopathology of the circadian clock: a narrative review

Okechukwu, C. E. (2022) · The Egyptian Journal of Neurology Psychiatry and Neurosurgery · doi:10.1186/s41983-022-00468-8 · Cited by 20

Light Intervention Effects on Circadian Activity Rhythm Parameters and Nighttime Sleep in Dementia Assessed by Wrist Actigraphy: A Systematic Review and Meta-Analysis

Canazei, M., Papousek, I., & Weiss, E. M. (2021) · The Gerontologist · doi:10.1093/geront/gnab168 · Cited by 13

Single nucleotide polymorphisms (SNPs) in circadian genes: Impact on gene function and phenotype

Barış, İ., Özcan, O., & Kavaklı, İ. H. (2023) · Advances in protein chemistry and structural biology · doi:10.1016/bs.apcsb.2023.03.002 · Cited by 13

The circadian rhythm as therapeutic target in inflammatory bowel disease

Post, Z., Zilberstein, N., & Keshavarzian, A. (2024) · Journal of the Canadian Association of Gastroenterology · doi:10.1093/jcag/gwae027 · Cited by 15

Disrupted Sleep Homeostasis and Altered Expressions of Clock Genes in Rats with Chronic Lead Exposure

Hsu, C., Chuang, Y., Chang, F., Chuang, H., Chiou, T. T., & Lee, C. (2021) · Toxics · doi:10.3390/toxics9090217 · Cited by 14

Acute Myocardial Infarction and Daylight Saving Time Transitions: Is There a Risk?

Čulić, V., & Kantermann, T. (2021) · Clocks & Sleep · doi:10.3390/clockssleep3040039 · Cited by 13

Chronodisruption and Ambulatory Circadian Monitoring in Cancer Patients: Beyond the Body Clock

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The Role of Circadian Clock Genes in Critical Illness: The Potential Role of Translational Clock Gene Therapies for Targeting Inflammation, Mitochondrial Function, and Muscle Mass in Intensive Care

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Circadian rhythm, hypoxia, and cellular senescence: From molecular mechanisms to targeted strategies

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Circadian rhythm disturbance impairs intestinal mucus barrier and immune microenvironment via sebacic acid-mediated gut dysbiosis

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Pharmacokinetics-based Chronotherapy

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Time for circadian medicine

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Targeting Rev-Erbα to protect against ischemia-reperfusion-induced acute lung injury in rats

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Role of age, menopausal status, and symptoms in midlife women: Examination of sleep patterns and rest-activity circadian rhythms

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Implications of circadian disruption on intervertebral disc degeneration: The mediating role of sympathetic nervous system

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The circadian clock regulates rhythmic erythropoietin expression in the murine kidney

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Advances in circadian clock regulation of reproduction

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ClinCirc identifies alterations of the circadian peripheral oscillator in critical care patients

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Exploration of the anti-insomnia mechanism of Ganoderma by central-peripheral multi-level interaction network analysis

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The Influence of Artificial Light at Night on Asthma and Allergy, Mental Health, and Cancer Outcomes: A Systematic Scoping Review Protocol

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Circadian lifestyle determinants of immune checkpoint inhibitor efficacy

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One Health: Circadian Medicine Benefits Both Non-human Animals and Humans Alike

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Molecular Pathways Regulating Circadian Rhythm and Associated Diseases

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Phenome-wide Analysis of Diseases in Relation to Objectively Measured Sleep Traits and Comparison with Subjective Sleep Traits in 88,461 Adults

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The 50th anniversary of the Konopka and Benzer 1971 paper in PNAS: “Clock Mutants of Drosophila melanogaster ”

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The circadian regulation of extracellular ATP

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High-throughput quantitation of trace level melatonin in human milk by on-line enrichment liquid chromatography-tandem mass spectrometry

Jin, W., Gui, J., Li, G., Jiang, F., & Han, D. (2021) · Analytica Chimica Acta · doi:10.1016/j.aca.2021.338764 · Cited by 10

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Circadian Rhythms, Disease and Chronotherapy

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Special Issue on “Research on Circadian Rhythms in Health and Disease”

Gubin, D. G., Cornélissen, G., Stefani, O., & Weinert, D. (2023) · Applied Sciences · doi:10.3390/app131910728