A Serum Shock Induces Circadian Gene Expression in Mammalian Tissue Culture Cells

Single-Step Method of RNA Isolation by Acid Guanidinium Thiocyanate–Phenol–Chloroform Extraction

Chomczynski, P., & Sacchi, N. (1987) · Analytical Biochemistry · doi:10.1006/abio.1987.9999 · Cited by 65,240 · see citing works

Single-step method of RNA isolation by acid guanidinium thiocyanate-phenol-chloroform extraction

Chomczyński, P., & Sacchi, N. (1987) · Analytical Biochemistry · doi:10.1016/0003-2697(87)90021-2 · Cited by 47,092 · see citing works

Mutagenesis and Mapping of a Mouse Gene, <i>Clock</i> , Essential for Circadian Behavior

Vitaterna, M. H., King, D. P., Chang, A.-M., Kornhauser, J. M., Lowrey, P. L., McDonald, J. D., Dove, W. F., Pinto, L. H., Turek, F. W., & Takahashi, J. S. (1994) · Science · doi:10.1126/science.8171325 · Cited by 1,632 · see citing works

Individual neurons dissociated from rat suprachiasmatic nucleus express independently phased circadian firing rhythms.

Welsh, D. K., Logothetis, D., Meister, M., & Reppert, S. (1995) · Neuron · doi:10.1016/0896-6273(95)90214-7 · Cited by 1,535 · see citing works

Neural regulation of circadian rhythms.

Rusak, B., & Zucker, I. (1979) · Physiological Reviews · doi:10.1152/physrev.1979.59.3.449 · Cited by 1,402 · see citing works

Positional Cloning of the Mouse Circadian Gene

King, D. P., Zhao, Y., Sangoram, A. M., Wilsbacher, L. D., Tanaka, M., Antoch, M. P., Steeves, T. D. L., Vitaterna, M. H., Kornhauser, J. M., Lowrey, P. L., et al. (1997) · Cell · doi:10.1016/s0092-8674(00)80245-7 · Cited by 1,382 · see citing works

Light-Induced Resetting of a Mammalian Circadian Clock Is Associated with Rapid Induction of the Transcript

Shigeyoshi, Y., Taguchi, K., Yamamoto, S., Takekida, S., Yan, L., Tei, H., Moriya, T., Shibata, S., Loros, J. J., Dunlap, J. C., et al. (1997) · Cell · doi:10.1016/s0092-8674(00)80494-8 · Cited by 891 · see citing works

A Differential Response of Two Putative Mammalian Circadian Regulators, mper1and mper2, to Light

Albrecht, U., Sun, Z. S., Eichele, G., & Lee, C. C. (1997) · Cell · doi:10.1016/s0092-8674(00)80495-x · Cited by 879 · see citing works

Circadian oscillation of a mammalian homologue of the Drosophila period gene

Tei, H., Okamura, H., Shigeyoshi, Y., Fukuhara, C., Ozawa, R., Hirose, M., & Sakaki, Y. (1997) · Nature · doi:10.1038/39086 · Cited by 792 · see citing works

A diffusible coupling signal from the transplanted suprachiasmatic nucleus controlling circadian locomotor rhythms

Silver, R., LeSauter, J., Tresco, P. A., & Lehman, M. N. (1996) · Nature · doi:10.1038/382810a0 · Cited by 792 · see citing works

Two period Homologs: Circadian Expression and Photic Regulation in the Suprachiasmatic Nuclei

Shearman, L. P., Zylka, M. J., Weaver, D. R., Kolakowski, L. F., & Reppert, S. M. (1997) · Neuron · doi:10.1016/s0896-6273(00)80417-1 · Cited by 781 · see citing works

Circadian Rhythms in Cultured Mammalian Retina

Tosini, G., & Menaker, M. (1996) · Science · doi:10.1126/science.272.5260.419 · Cited by 716 · see citing works

RIGUI, a putative mammalian ortholog of the Drosophila period gene.

Sun, Z. S., Albrecht, U., Zhuchenko, O., Bailey, J., Eichele, G., & Lee, C.-C. (1997) · Cell · doi:10.1016/s0092-8674(00)80366-9 · Cited by 706 · see citing works

Functional Identification of the Mouse Circadian Clock Gene by Transgenic BAC Rescue

Antoch, M. P., Song, E.-J., Chang, A., Vitaterna, M. H., Zhao, Y., Wilsbacher, L. D., Sangoram, A. M., King, D. P., Pinto, L. H., & Takahashi, J. S. (1997) · Cell · doi:10.1016/s0092-8674(00)80246-9 · Cited by 665 · see citing works

Independent Photoreceptive Circadian Clocks Throughout Drosophila

Plautz, J. D., Kaneko, M. A. N., Hall, J. C., & Kay, S. A. (1997) · Science · doi:10.1126/science.278.5343.1632 · Cited by 640 · see citing works

The melatonin rhythm-generating enzyme: molecular regulation of serotonin N-acetyltransferase in the pineal gland.

Klein, D. C., Coon, S. L., Roseboom, P. H., Weller, J. L., Bernard, M., Gastel, J. A., Zatz, M., Iuvone, P. M., Rodríguez, I. R., Bégay, V., et al. (1997) · PubMed · Cited by 550 · see citing works

Cellular Construction of a Circadian Clock: Period Determination in the Suprachiasmatic Nuclei

Liu, C., Weaver, D. R., Strogatz, S. H., & Reppert, S. M. (1997) · Cell · doi:10.1016/s0092-8674(00)80473-0 · Cited by 508 · see citing works

Neurospora wc-1 and wc-2 : Transcription, Photoresponses, and the Origins of Circadian Rhythmicity

Crosthwaite, S. K., Dunlap, J., & Loros, J. (1997) · Science · doi:10.1126/science.276.5313.763 · Cited by 503 · see citing works

A light-entrainment mechanism for the Drosophila circadian clock

Zeng, H., Qian, Z., Myers, M. P., & Rosbash, M. (1996) · Nature · doi:10.1038/380129a0 · Cited by 479 · see citing works

Light-Induced Degradation of TIMELESS and Entrainment of the Drosophila Circadian Clock

Myers, M. P., Wager‐Smith, K., Rothenfluh, A., & Young, M. W. (1996) · Science · doi:10.1126/science.271.5256.1736 · Cited by 465 · see citing works

Expression of the period clock gene within different cell types in the brain of Drosophila adults and mosaic analysis of these cells' influence on circadian behavioral rhythms

Ewer, J., Frisch, B., Hamblen-Coyle, M., et al. (1992) · Journal of Neuroscience · doi:10.1523/jneurosci.12-09-03321.1992 · Cited by 333 · see citing works

The DBP gene is expressed according to a circadian rhythm in the suprachiasmatic nucleus and influences circadian behavior

Lopez‐Molina, L., Conquet, F., Dubois‐Dauphin, M., & Schibler, U. (1997) · The EMBO Journal · doi:10.1093/emboj/16.22.6762 · Cited by 300 · see citing works

Circadian transcription of the cholesterol 7 alpha hydroxylase gene may involve the liver-enriched bZIP protein DBP.Preprint

Lavery, D. J., & Schibler, U. (1993) · Genes & Development · doi:10.1101/gad.7.10.1871 · Cited by 300 · see citing works

Protein synthesis inhibitors differentially superinduce c‐fos and c‐jun by three distinct mechanisms: lack of evidence for labile repressors.

Edwards, D. R., & Mahadevan, L. C. (1992) · The EMBO Journal · doi:10.1002/j.1460-2075.1992.tb05306.x · Cited by 280 · see citing works

GENETIC AND MOLECULAR ANALYSIS OF CIRCADIAN RHYTHMS

Dunlap, J. (1996) · Annual Review of Genetics · doi:10.1146/annurev.genet.30.1.579 · Cited by 265 · see citing works

Spatial and Temporal Expression of theperiodandtimelessGenes in the Developing Nervous System ofDrosophila: Newly Identified Pacemaker Candidates and Novel Features of Clock Gene Product Cycling

Kaneko, M. A. N., Helfrich‐Förster, C., & Hall, J. C. (1997) · Journal of Neuroscience · doi:10.1523/jneurosci.17-17-06745.1997 · Cited by 256 · see citing works

TEF, a transcription factor expressed specifically in the anterior pituitary during embryogenesis, defines a new class of leucine zipper proteins.Preprint

Drolet, D. W., Scully, K. M., Simmons, D. M., Wegner, M., Chu, K. T., Swanson, L. W., & Rosenfeld, M. G. (1991) · Genes & Development · doi:10.1101/gad.5.10.1739 · Cited by 245 · see citing works

Protein Synthesis Inhibitors Reveal Differential Regulation of Mitogen-Activated Protein Kinase and Stress-Activated Protein Kinase Pathways That Converge on Elk-1

Zinck, R., Cahill, M. A., Kracht, M., Sachsenmaier, C., Hipskind, R. A., & Nordheim, A. (1995) · Molecular and Cellular Biology · doi:10.1128/mcb.15.9.4930 · Cited by 243 · see citing works

Constitutive overexpression of the Drosophila period protein inhibits period mRNA cycling.

Zeng, H., Hardin, P. E., & Rosbash, M. (1994) · The EMBO Journal · doi:10.1002/j.1460-2075.1994.tb06666.x · Cited by 222 · see citing works

Specific stimulation of actin gene transcription by epidermal growth factor and cycloheximide.

Elder, P. K., Schmidt, L. J., Ono, T., et al. (1984) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.81.23.7476 · Cited by 215 · see citing works

Posttranscriptional regulation of c-fos mRNA expression

Rahmsdorf, H. J., Schönthal, A. H., Angel, P. E., et al. (1987) · Nucleic Acids Research · doi:10.1093/nar/15.4.1643 · Cited by 213 · see citing works

Molecular Neurobiology and Genetics of Circadian Rhythms in Mammals

Takahashi, J. S. (1995) · Annual Review of Neuroscience · doi:10.1146/annurev.ne.18.030195.002531 · Cited by 199 · see citing works

Melatonin: Generation and Modulation of Avian Circadian Rhythms

Gwinner, E., Hau, M., & Heigl, S. (1997) · Brain Research Bulletin · doi:10.1016/s0361-9230(97)00224-4 · Cited by 176 · see citing works

High accumulation of components of the RNA polymerase II transcription machinery in rodent spermatids

Schmidt, E. E., & Schibler, U. (1995) · Development · doi:10.1242/dev.121.8.2373 · Cited by 157 · see citing works

The two PAR leucine zipper proteins, TEF and DBP, display similar circadian and tissue‐specific expression, but have different target promoter preferences.

Fonjallaz, P., Ossipow, V., Wanner, G., & Schibler, U. (1996) · The EMBO Journal · doi:10.1002/j.1460-2075.1996.tb00365.x · Cited by 151 · see citing works

Light, immediate-early genes, and circadian rhythms

Kornhauser, J. M., Mayo, K. E., & Takahashi, J. S. (1996) · Behavior Genetics · doi:10.1007/bf02359382 · Cited by 148 · see citing works

Mitogen-Activated Protein Kinase

Adam, L. P. (1996) · Elsevier eBooks · doi:10.1016/b978-012078160-7/50016-0 · Cited by 131 · see citing works

A Screen for Genes Induced in the Suprachiasmatic Nucleus by Light

Morris, M. E., Viswanathan, N., Kuhlman, S. J., Davis, F. C., & Weitz, C. J. (1998) · Science · doi:10.1126/science.279.5356.1544 · Cited by 114 · see citing works

Aldosterone and potassium homeostasis

Rabinowitz, L. (1996) · Kidney International · doi:10.1038/ki.1996.258 · Cited by 104 · see citing works

Circadian clock in cell culture: II. In vitro photic entrainment of melatonin oscillation from dissociated chick pineal cells

Robertson, L. G., & Takahashi, J. S. (1988) · Journal of Neuroscience · doi:10.1523/jneurosci.08-01-00022.1988 · Cited by 100 · see citing works

Circadian-clock regulation of gene expression

Takahashi, J. S. (1993) · Current Opinion in Genetics & Development · doi:10.1016/0959-437x(93)90038-q · Cited by 90 · see citing works

Editorial: Ultradian, circadian, and stress–related hypothalamic–pituitary–adrenal axis activity–a dynamic digital–to–analog Modulation

Chrousos, G. P. (1998) · Endocrinology · doi:10.1210/endo.139.2.5857 · Cited by 83 · see citing works

The circadian system of c-fos deficient mice

Honrado, G. I., Johnson, R. S., Golombek, D. A., Spiegelman, B. M., Papaioannou, V. E., & Ralph, M. R. (1996) · Journal of Comparative Physiology A · doi:10.1007/bf00190186 · Cited by 81 · see citing works

Multioscillatory Circadian Organization in a Vertebrate,Iguana iguana

Tosini, G., & Menaker, M. (1998) · Journal of Neuroscience · doi:10.1523/jneurosci.18-03-01105.1998 · Cited by 73 · see citing works

Endocrine Mechanisms of Blood Pressure Rhythms

Portaluppi, F., Vergnani, L., Manfredini, R., & FERSINI, C. (1996) · Annals of the New York Academy of Sciences · doi:10.1111/j.1749-6632.1996.tb26711.x · Cited by 69 · see citing works

Circadian clocks

Hastings, M. H. (1997) · Current Biology · doi:10.1016/s0960-9822(06)00350-2 · Cited by 43 · see citing works

Circadian rhythms: From behaviour to molecules

Rosato, E., Piccin, A., & Kyriacou, C. P. (1997) · BioEssays · doi:10.1002/bies.950191206 · Cited by 37 · see citing works

Phototransduction cascade and circadian oscillator in chicken pineal gland

Okano, T., & Fukada, Y. (1997) · Journal of Pineal Research · doi:10.1111/j.1600-079x.1997.tb00316.x · Cited by 32 · see citing works

Coordination of circadian timing in mammals

Reppert, S. M., & Weaver, D. R. (2002) · Nature · doi:10.1038/nature00965 · Cited by 4,379 · see citing works

Molecular Bases for Circadian Clocks

Dunlap, J. C. (1999) · Cell · doi:10.1016/s0092-8674(00)80566-8 · Cited by 2,900 · see citing works

Obesity and Metabolic Syndrome in Circadian <i>Clock</i> Mutant Mice

Turek, F. W., Joshu, C., Kohsaka, A., Lin, E., Ivanova, G., McDearmon, E., Laposky, A., Losee-Olson, S., Easton, A., Jensen, D. R., et al. (2005) · Science · doi:10.1126/science.1108750 · Cited by 2,485 · see citing works

The mammalian circadian timing system: organization and coordination of central and peripheral clocks

Dibner, C., Schibler, U., & Albrecht, U. (2010) · Annual Review of Physiology · doi:10.1146/annurev-physiol-021909-135821 · Cited by 2,421 · see citing works

Restricted feeding uncouples circadian oscillators in peripheral tissues from the central pacemaker in the suprachiasmatic nucleus

Damiola, F., Le Minh, N., Preitner, N., Kornmann, B., Fleury-Olela, F., & Schibler, U. (2000) · Genes &amp; Development · doi:10.1101/gad.183500 · Cited by 2,394 · see citing works

PERIOD2::LUCIFERASE real-time reporting of circadian dynamics reveals persistent circadian oscillations in mouse peripheral tissues

Yoo, S.-H., Yamazaki, S., Lowrey, P. L., Shimomura, K., Ko, C. H., Buhr, E. D., Siepka, S. M., Hong, H.-K., Oh, W. J., Yoo, O. J., et al. (2004) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0308709101 · Cited by 2,329 · see citing works

Central and Peripheral Circadian Clocks in Mammals

Mohawk, J. A., Green, C. B., & Takahashi, J. S. (2012) · Annual Review of Neuroscience · doi:10.1146/annurev-neuro-060909-153128 · Cited by 2,265 · see citing works

The Orphan Nuclear Receptor REV-ERBα Controls Circadian Transcription within the Positive Limb of the Mammalian Circadian Oscillator

Preitner, N., Damiola, F., Luis-Lopez-Molina, Zakany, J., Duboule, D., Albrecht, U., & Schibler, U. (2002) · Cell · doi:10.1016/s0092-8674(02)00825-5 · Cited by 2,198 · see citing works

Circadian integration of metabolism and energetics

Bass, J., & Takahashi, J. S. (2010) · Science · doi:10.1126/science.1195027 · Cited by 1,910 · see citing works

Resetting central and peripheral circadian oscillators in transgenic rats

Yamazaki, S., Numano, R., Abe, M., Hida, A., Takahashi, R.-I., Ueda, M., Block, G. D., Sakaki, Y., Menaker, M., & Tei, H. (2000) · Science · doi:10.1126/science.288.5466.682 · Cited by 1,907 · see citing works

Resetting of circadian time in peripheral tissues by glucocorticoid signaling

Balsalobre, A., Brown, S. A., Marcacci, L., Tronche, F., Kellendonk, C., Reichardt, H. M., Schütz, G., & Schibler, U. (2000) · Science · doi:10.1126/science.289.5488.2344 · Cited by 1,859 · see citing works

mCRY1 and mCRY2 are essential components of the negative limb of the circadian clock feedback loop

Kume, K., Zylka, M. J., Sriram, S., Shearman, L. P., Weaver, D. R., Jin, X., Maywood, E. S., Hastings, M. H., & Reppert, S. M. (1999) · Cell · doi:10.1016/s0092-8674(00)81014-4 · Cited by 1,617 · see citing works

Disruption of the clock components CLOCK and BMAL1 leads to hypoinsulinaemia and diabetes

Marcheva, B., Ramsey, K. M., Buhr, E. D., Kobayashi, Y., Su, H., Ko, C. H., Ivanova, G., Omura, C., Mo, S., Vitaterna, M. H., et al. (2010) · Nature · doi:10.1038/nature09253 · Cited by 1,525 · see citing works

Molecular analysis of mammalian circadian rhythms

Reppert, S. M., & Weaver, D. R. (2001) · Annual Review of Physiology · doi:10.1146/annurev.physiol.63.1.647 · Cited by 1,444 · see citing works

SIRT1 regulates circadian clock gene expression through PER2 deacetylation

Asher, G., Gatfield, D., Stratmann, M., Reinke, H., Dibner, C., Kreppel, F., Mostoslavsky, R., Alt, F. W., & Schibler, U. (2008) · Cell · doi:10.1016/j.cell.2008.06.050 · Cited by 1,376 · see citing works

Suprachiasmatic Nucleus: Cell Autonomy and Network Properties

Welsh, D. K., Takahashi, J. S., & Kay, S. A. (2010) · Annual Review of Physiology · doi:10.1146/annurev-physiol-021909-135919 · Cited by 1,216 · see citing works

Physiological significance of a peripheral tissue circadian clock

Lamia, K. A., Storch, K.-F., & Weitz, C. J. (2008) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0806717105 · Cited by 1,048 · see citing works

Mammalian circadian biology: elucidating genome-wide levels of temporal organization

Lowrey, P. L., & Takahashi, J. S. (2004) · Annual Review of Genomics and Human Genetics · doi:10.1146/annurev.genom.5.061903.175925 · Cited by 976 · see citing works

Temperature as a Universal Resetting Cue for Mammalian Circadian Oscillators

Buhr, E. D., Yoo, S.-H., & Takahashi, J. S. (2010) · Science · doi:10.1126/science.1195262 · Cited by 917 · see citing works

Timing to perfection: the biology of central and peripheral circadian clocks

Albrecht, U. (2012) · Neuron · doi:10.1016/j.neuron.2012.04.006 · Cited by 915 · see citing works

The Meter of Metabolism

Green, C. B., Takahashi, J. S., & Bass, J. (2008) · Cell · doi:10.1016/j.cell.2008.08.022 · Cited by 902 · see citing works

Nonredundant roles of the mPer1 and mPer2 genes in the mammalian circadian clock.

Zheng, B., Albrecht, U., Kaasik, K., Sage, M., Lu, W., Vaishnav, S., Li, Q., Sun, Z. S., Eichele, G., Bradley, A., et al. (2001) · Cell · doi:10.1016/s0092-8674(01)00380-4 · Cited by 900 · see citing works

Epigenetic mechanisms in memory formation

Levenson, J. M., & Sweatt, J. D. (2005) · Nature Reviews Neuroscience · doi:10.1038/nrn1604 · Cited by 767 · see citing works

Time of feeding and the intrinsic circadian clock drive rhythms in hepatic gene expression.

Vollmers, C., Gill, S., DiTacchio, L., Pulivarthy, S. R., Le, H. D., & Panda, S. (2009) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0909591106 · Cited by 765 · see citing works

Generation of the Melatonin Endocrine Message in Mammals: A Review of the Complex Regulation of Melatonin Synthesis by Norepinephrine, Peptides, and Other Pineal Transmitters

Simonneaux, V., & Ribelayga, C. (2003) · Pharmacological Reviews · doi:10.1124/pr.55.2.2 · Cited by 740 · see citing works

Molecular components of the mammalian circadian clock

Buhr, E. D., & Takahashi, J. S. (2013) · Handbook of experimental pharmacology · doi:10.1007/978-3-642-25950-0_1 · Cited by 738 · see citing works

Bioluminescence imaging of individual fibroblasts reveals persistent, independently phased circadian rhythms of clock gene expression

Welsh, D. K., Yoo, S.-H., Liu, A. C., Takahashi, J. S., & Kay, S. A. (2004) · Current Biology · doi:10.1016/j.cub.2004.11.057 · Cited by 726 · see citing works

The mPer2 gene encodes a functional component of the mammalian circadian clock

Zheng, B., Larkin, D. W., Albrecht, U., Sun, Z. S., Sage, M., Eichele, G., Lee, C. C., & Bradley, A. (1999) · Nature · doi:10.1038/22118 · Cited by 718 · see citing works

Circadian rhythms in isolated brain regions

Abe, M., Herzog, E. D., Yamazaki, S., Straume, M., Tei, H., Sakaki, Y., Menaker, M., & Block, G. D. (2002) · The Journal of Neuroscience · doi:10.1523/jneurosci.22-01-00350.2002 · Cited by 681 · see citing works

The circadian clock: pacemaker and tumour suppressor

Fu, L., & Lee, C. C. (2003) · Nature reviews. Cancer · doi:10.1038/nrc1072 · Cited by 678 · see citing works

Transcriptional coactivator PGC-1α integrates the mammalian clock and energy metabolism

Liu, C., Li, S., Liu, T., Borjigin, J., & Lin, J. D. (2007) · Nature · doi:10.1038/nature05767 · Cited by 643 · see citing works

Circadian Rhythms: Mechanisms and Therapeutic Implications

Levi, F., & Schibler, U. (2007) · Annual Review of Pharmacology and Toxicology · doi:10.1146/annurev.pharmtox.47.120505.105208 · Cited by 645 · see citing works

Crosstalk between components of circadian and metabolic cycles in mammals

Asher, G., & Schibler, U. (2011) · Cell Metabolism · doi:10.1016/j.cmet.2011.01.006 · Cited by 601 · see citing works

Crosstalk between metabolism and circadian clocks

Reinke, H., & Asher, G. (2019) · Nature Reviews Molecular Cell Biology · doi:10.1038/s41580-018-0096-9 · Cited by 598 · see citing works

Rhythms of Mammalian Body Temperature Can Sustain Peripheral Circadian Clocks

Brown, S. A., Zumbrunn, G., Fleury-Olela, F., Preitner, N., & Schibler, U. (2002) · Current Biology · doi:10.1016/s0960-9822(02)01145-4 · Cited by 589 · see citing works

Light activates the adrenal gland: Timing of gene expression and glucocorticoid release

Ishida, A., Mutoh, T., Ueyama, T., Bando, H., Masubuchi, S., Nakahara, D., Tsujimoto, G., & Okamura, H. (2005) · Cell Metabolism · doi:10.1016/j.cmet.2005.09.009 · Cited by 589 · see citing works

NPAS2: an analog of clock operative in the mammalian forebrain

Reick, M., Garcia, J. A., Dudley, C., & McKnight, S. L. (2001) · Science · doi:10.1126/science.1060699 · Cited by 572 · see citing works

Metabolism and cancer: the circadian clock connection

Sahar, S., & Sassone-Corsi, P. (2009) · Nature Reviews Cancer · doi:10.1038/nrc2747 · Cited by 551 · see citing works

The Functional and Clinical Significance of the 24-Hour Rhythm of Circulating Glucocorticoids

Oster, H., Challet, E., Ott, V., Arvat, E., de Kloet, E. R., Dijk, D.-J., Lightman, S., Vgontzas, A., & Van Cauter, E. (2017) · Endocrine Reviews · doi:10.1210/er.2015-1080 · Cited by 548 · see citing works

Circadian Mechanisms in Medicine

Allada, R., & Bass, J. (2021) · New England Journal of Medicine · doi:10.1056/nejmra1802337 · Cited by 519 · see citing works

Circadian rhythms and the molecular clock in cardiovascular biology and disease

Crnko, S., Du Pré, B. C., Sluijter, J. P. G., & Van Laake, L. W. (2019) · Nature Reviews Cardiology · doi:10.1038/s41569-019-0167-4 · Cited by 499 · see citing works

Control of Mammalian Circadian Rhythm by CKIε-Regulated Proteasome-Mediated PER2 Degradation

Eide, E. J., Woolf, M. F., Kang, H., Woolf, P., Hurst, W., Camacho, F., Vielhaber, E. L., Giovanni, A., & Virshup, D. M. (2005) · Molecular and Cellular Biology · doi:10.1128/mcb.25.7.2795-2807.2005 · Cited by 495 · see citing works

Glucocorticoids and the circadian clock

Dickmeis, T. (2009) · Journal of Endocrinology · doi:10.1677/joe-08-0415 · Cited by 494 · see citing works

Intrinsic circadian clock of the mammalian retina: importance for retinal processing of visual information

Storch, K.-F., Paz, C., Signorovitch, J., Raviola, E., Pawlyk, B., Li, T., & Weitz, C. J. (2007) · Cell · doi:10.1016/j.cell.2007.06.045 · Cited by 460 · see citing works

Circadian clocks: regulators of endocrine and metabolic rhythms

Hastings, M., O’Neill, J. S., & Maywood, E. S. (2007) · Journal of Endocrinology · doi:10.1677/joe-07-0378 · Cited by 426 · see citing works

Altered patterns of sleep and behavioral adaptability in NPAS2-deficient mice

Dudley, C. A., Erbel-Sieler, C., Estill, S. J., Reick, M., Franken, P., Pitts, S., & McKnight, S. L. (2003) · Science · doi:10.1126/science.1082795 · Cited by 415 · see citing works

Impact of Sleep and Its Disturbances on Hypothalamo-Pituitary-Adrenal Axis Activity

Balbo, M., Leproult, R., & Van Cauter, E. (2010) · International Journal of Endocrinology · doi:10.1155/2010/759234 · Cited by 408 · see citing works

Circadian system, sleep and endocrinology

Morris, C. J., Aeschbach, D., & Scheer, F. A. J. L. (2012) · Molecular and Cellular Endocrinology · doi:10.1016/j.mce.2011.09.003 · Cited by 403 · see citing works

Circadian clock protein BMAL1 regulates IL-1β in macrophages via NRF2

Early, J. O., Menon, D., Wyse, C. A., Cervantes-Silva, M. P., Zaslona, Z., Carroll, R. G., Palsson-McDermott, E. M., Angiari, S., Ryan, D. G., Corcoran, S. E., et al. (2018) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1800431115 · Cited by 389 · see citing works

A Role for Glycogen Synthase Kinase-3β in the Mammalian Circadian Clock

Iitaka, C., Miyazaki, K., Akaike, T., & Ishida, N. (2005) · Journal of Biological Chemistry · doi:10.1074/jbc.m503526200 · Cited by 373 · see citing works

Sleep and circadian rhythms: key components in the regulation of energy metabolism

Laposky, A. D., Bass, J., Kohsaka, A., & Turek, F. W. (2008) · FEBS Letters · doi:10.1016/j.febslet.2007.06.079 · Cited by 351 · see citing works

Sex differences in circadian timing systems: implications for disease

Bailey, M., & Silver, R. (2014) · Frontiers in Neuroendocrinology · doi:10.1016/j.yfrne.2013.11.003 · Cited by 348 · see citing works

Circadian control of glucose metabolism

Kalsbeek, A., la Fleur, S., & Fliers, E. (2014) · Molecular Metabolism · doi:10.1016/j.molmet.2014.03.002 · Cited by 338 · see citing works

The circadian molecular clock creates epidermal stem cell heterogeneity

Janich, P., Pascual, G., Merlos-Suárez, A., Batlle, E., Ripperger, J., Albrecht, U., Cheng, H.-Y. M., Obrietan, K., Di Croce, L., & Benitah, S. A. (2011) · Nature · doi:10.1038/nature10649 · Cited by 326 · see citing works

Modified-release hydrocortisone to provide circadian cortisol profiles

Debono, M., Ghobadi, C., Rostami-Hodjegan, A., Huatan, H., Campbell, M. J., Newell-Price, J., Darzy, K., Merke, D. P., Arlt, W., & Ross, R. J. (2009) · The Journal of Clinical Endocrinology &amp; Metabolism · doi:10.1210/jc.2008-2380 · Cited by 322 · see citing works

Melatonin, endocrine pancreas and diabetes

Peschke, E. (2008) · Journal of Pineal Research · doi:10.1111/j.1600-079x.2007.00519.x · Cited by 309 · see citing works

Circadian rhythm of adrenal glucocorticoid: its regulation and clinical implications

Chung, S., Son, G. H., & Kim, K. (2011) · Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease · doi:10.1016/j.bbadis.2011.02.003 · Cited by 305 · see citing works

Circadian Clocks and Metabolism

Marcheva, B., Ramsey, K. M., Peek, C. B., Affinati, A., Maury, E., & Bass, J. (2013) · Handbook of Experimental Pharmacology · doi:10.1007/978-3-642-25950-0_6 · Cited by 282 · see citing works

Endophenotypes in bipolar disorder

Lenox, R. H., Gould, T. D., & Manji, H. K. (2002) · American Journal of Medical Genetics · doi:10.1002/ajmg.10360 · Cited by 264 · see citing works

Interconnection between circadian clocks and thyroid function

Ikegami, K., Refetoff, S., Van Cauter, E., & Yoshimura, T. (2019) · Nature Reviews Endocrinology · doi:10.1038/s41574-019-0237-z · Cited by 251 · see citing works

The circadian clock in cancer development and therapy

Fu, L., & Kettner, N. M. (2013) · Progress in Molecular Biology and Translational Science · doi:10.1016/b978-0-12-396971-2.00009-9 · Cited by 251 · see citing works

Circadian clocks: setting time by food

Mendoza, J. (2007) · Journal of Neuroendocrinology · doi:10.1111/j.1365-2826.2006.01510.x · Cited by 257 · see citing works

Review: Replication of cortisol circadian rhythm: new advances in hydrocortisone replacement therapy

Chan, S., & Debono, M. (2010) · Therapeutic Advances in Endocrinology and Metabolism · doi:10.1177/2042018810380214 · Cited by 243 · see citing works

Development of the circadian oscillator during differentiation of mouse embryonic stem cells in vitro

Yagita, K., Horie, K., Koinuma, S., Nakamura, W., Yamanaka, I., Urasaki, A., Shigeyoshi, Y., Kawakami, K., Shimada, S., Takeda, J., et al. (2010) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0913256107 · Cited by 241 · see citing works

Circadian timing of metabolism in animal models and humans

Dibner, C., & Schibler, U. (2015) · Journal of Internal Medicine · doi:10.1111/joim.12347 · Cited by 237 · see citing works

Circadian rhythms in glucose and lipid metabolism in nocturnal and diurnal mammals

Kumar Jha, P., Challet, E., & Kalsbeek, A. (2015) · Molecular and Cellular Endocrinology · doi:10.1016/j.mce.2015.01.024 · Cited by 235 · see citing works

Genetics of circadian rhythms and sleep in human health and disease

Lane, J. M., Qian, J., Mignot, E., Redline, S., Scheer, F. A. J. L., & Saxena, R. (2023) · Nature Reviews Genetics · doi:10.1038/s41576-022-00519-z · Cited by 236 · see citing works

DNA microarray analyses of circadian timing: the genomic basis of biological time

Duffield, G. E. (2003) · Journal of Neuroendocrinology · doi:10.1046/j.1365-2826.2003.01082.x · Cited by 234 · see citing works

Circadian rhythms in the development of obesity: potential role for the circadian clock within the adipocyte

Bray, M. S., & Young, M. E. (2007) · Obesity Reviews · doi:10.1111/j.1467-789x.2006.00277.x · Cited by 213 · see citing works

The impact of the circadian timing system on cardiovascular and metabolic function

Morris, C. J., Yang, J. N., & Scheer, F. A. J. L. (2012) · Progress in Brain Research · doi:10.1016/b978-0-444-59427-3.00019-8 · Cited by 215 · see citing works

Circadian Clock, Cancer, and Chemotherapy

Sancar, A., Lindsey-Boltz, L. A., Gaddameedhi, S., Selby, C. P., Ye, R., Chiou, Y.-Y., Kemp, M. G., Hu, J., Lee, J. H., & Ozturk, N. (2015) · Biochemistry · doi:10.1021/bi5007354 · Cited by 170 · see citing works

The hypersensitive glucocorticoid response specifically regulates period 1 and expression of circadian genes

Reddy, T. E., Gertz, J., Crawford, G. E., Garabedian, M. J., & Myers, R. M. (2012) · Molecular and Cellular Biology · doi:10.1128/mcb.00062-12 · Cited by 149 · see citing works

Physiological responses to food intake throughout the day

Johnston, J. D. (2014) · Nutrition Research Reviews · doi:10.1017/s0954422414000055 · Cited by 158 · see citing works

Circadian rhythms – from genes to physiology and disease

Bollinger, T., & Schibler, U. (2014) · Swiss Medical Weekly · doi:10.4414/smw.2014.13984 · Cited by 152 · see citing works

Bioinformatic Analysis of Circadian Gene Oscillation in Mouse Aorta

Rudic, R. D., McNamara, P., Reilly, D., Grosser, T., Curtis, A.-M., Price, T. S., Panda, S., Hogenesch, J. B., & FitzGerald, G. A. (2005) · Circulation · doi:10.1161/circulationaha.105.568626 · Cited by 157 · see citing works

Indication of circadian oscillations in the rat pancreas

Mühlbauer, E., Wolgast, S., Finckh, U., Peschke, D., & Peschke, E. (2004) · FEBS Letters · doi:10.1016/s0014-5793(04)00322-9 · Cited by 147 · see citing works

The circadian clock and glucocorticoids – interactions across many time scales

Dickmeis, T., Weger, B. D., & Weger, M. (2013) · Molecular and Cellular Endocrinology · doi:10.1016/j.mce.2013.05.012 · Cited by 144 · see citing works

The adrenal peripheral clock: Glucocorticoid and the circadian timing system

Son, G. H., Chung, S., & Kim, K. (2011) · Frontiers in Neuroendocrinology · doi:10.1016/j.yfrne.2011.07.003 · Cited by 136 · see citing works

Minireview: Timely Ovulation: Circadian Regulation of the Female Hypothalamo-Pituitary-Gonadal Axis

de la Iglesia, H. O., & Schwartz, W. J. (2006) · Endocrinology · doi:10.1210/en.2005-1311 · Cited by 134 · see citing works

Biological clocks and the digestive system

Scheving, L. A. (2000) · Gastroenterology · doi:10.1053/gast.2000.9305 · Cited by 130 · see citing works

Mammalian circadian systems: Organization and modern life challenges

Finger, A., & Kramer, A. (2021) · Acta Physiologica · doi:10.1111/apha.13548 · Cited by 117 · see citing works

A Circadian Genomic Signature Common to Ketamine and Sleep Deprivation in the Anterior Cingulate Cortex

Orozco-Solis, R., Montellier, E., Aguilar-Arnal, L., Sato, S., Vawter, M. P., Bunney, B. G., Bunney, W. E., & Sassone-Corsi, P. (2017) · Biological Psychiatry · doi:10.1016/j.biopsych.2017.02.1176 · Cited by 119 · see citing works

The role of circadian rhythmicity in reproduction

Kennaway, D. J. (2005) · Human Reproduction Update · doi:10.1093/humupd/dmh054 · Cited by 120 · see citing works

Altered circadian clock gene expression in patients with schizophrenia

Johansson, A.-S., Owe-Larsson, B., Hetta, J., & Lundkvist, G. B. (2016) · Schizophrenia Research · doi:10.1016/j.schres.2016.04.029 · Cited by 120 · see citing works

Lipids around the Clock: Focus on Circadian Rhythms and Lipid Metabolism

Gnocchi, D., Pedrelli, M., Hurt-Camejo, E., & Parini, P. (2015) · Biology · doi:10.3390/biology4010104 · Cited by 115 · see citing works

Assessment of circadian function in fibroblasts of patients with bipolar disorder

Yang, S., Van Dongen, H. P. A., Wang, K., Berrettini, W., & Bućan, M. (2009) · Molecular Psychiatry · doi:10.1038/mp.2008.10 · Cited by 113 · see citing works

Circadian rhythms, food timing and obesity

Lopez-Minguez, J., Gómez-Abellán, P., & Garaulet, M. (2016) · Proceedings of the Nutrition Society · doi:10.1017/s0029665116000628 · Cited by 113 · see citing works

Circadian Rhythms, Skeletal Muscle Molecular Clocks, and Exercise

Schroder, E. A., & Esser, K. A. (2013) · Exercise and Sport Sciences Reviews · doi:10.1097/jes.0b013e3182a58a70 · Cited by 84 · see citing works

Clock Gene Expression in Adult Primate Suprachiasmatic Nuclei and Adrenal: Is the Adrenal a Peripheral Clock Responsive to Melatonin?

Valenzuela, F. J., Torres-Farfan, C., Richter, H. G., Mendez, N., Campino, C., Torrealba, F., Valenzuela, G. J., & Serón-Ferré, M. (2008) · Endocrinology · doi:10.1210/en.2007-1518 · Cited by 74 · see citing works

Circadian Rhythms in the CNS and Peripheral Clock Disorders: Role of the Biological Clock in Cardiovascular Diseases

Maemura, K., Takeda, N., & Nagai, R. (2007) · Journal of Pharmacological Sciences · doi:10.1254/jphs.fmj06003x2 · Cited by 73 · see citing works

The impact of glucocorticoids and statins on sleep quality

Szmyd, B., Rogut, M., Białasiewicz, P., & Gabryelska, A. (2021) · Sleep Medicine Reviews · doi:10.1016/j.smrv.2020.101380 · Cited by 66 · see citing works

Clocks and the black box: circadian influences on gonadotropin releasing hormone secretion

Chappell, P. E. (2005) · Journal of Neuroendocrinology · doi:10.1111/j.1365-2826.2005.01270.x · Cited by 62 · see citing works

A role for Id2 in regulating photic entrainment of the mammalian circadian system

Duffield, G. E., Watson, N. P., Mantani, A., Peirson, S. N., Robles-Murguia, M., Loros, J. J., Israel, M. A., & Dunlap, J. C. (2009) · Current Biology · doi:10.1016/j.cub.2008.12.052 · Cited by 59 · see citing works

Circadian transcription from beta cell function to diabetes pathophysiology

Perelis, M., Ramsey, K. M., Marcheva, B., & Bass, J. (2016) · Journal of Biological Rhythms · doi:10.1177/0748730416656949 · Cited by 57 · see citing works

Modulation of circadian clocks by nutrients and food factors

Oike, H. (2017) · Bioscience Biotechnology and Biochemistry · doi:10.1080/09168451.2017.1281722 · Cited by 53 · see citing works

p75 neurotrophin receptor is a clock gene that regulates oscillatory components of circadian and metabolic networks

Baeza-Raja, B., Eckel-Mahan, K., Zhang, L., Vagena, E., Tsigelny, I. F., Sassone-Corsi, P., Ptacek, L. J., & Akassoglou, K. (2013) · Journal of Neuroscience · doi:10.1523/jneurosci.2757-12.2013 · Cited by 44 · see citing works

When should I eat: A circadian view on food intake and metabolic regulation

Chamorro, R., Jouffe, C., Oster, H., Uhlenhaut, N. H., & Meyhöfer, S. M. (2023) · Acta Physiologica · doi:10.1111/apha.13936 · Cited by 40 · see citing works

Characteristics of Circadian Gene Expressions in Mice White Adipose Tissue and 3T3-L1 Adipocytes

Aoyagi, T., Shimba, S., & Tezuka, M. (2005) · Journal of Health Science · doi:10.1248/jhs.51.21 · Cited by 37 · see citing works

Central Circadian Clock Regulates Energy Metabolism

Ding, G., Gong, Y., Eckel-Mahan, K. L., & Sun, Z. (2018) · Advances in Experimental Medicine and Biology · doi:10.1007/978-981-13-1286-1_5 · Cited by 33 · see citing works

Circadian regulation of cellular physiology

Peek, C. B., Ramsey, K. M., Levine, D. C., Marcheva, B., Perelis, M., & Bass, J. (2015) · Methods in Enzymology · doi:10.1016/bs.mie.2014.10.006 · Cited by 35 · see citing works

[Expression of human ERMAP gene in different cell lines].

He, Y., Zhang, X., Ye, T.-Z., et al. (2005) · PubMed · Cited by 1 · see citing works

Susceptibility of adherent versus suspension target cells derived from adherent tissue culture lines to cell-mediated cytotoxicity in rapid 51Cr-release assays

Dorfman, N. A., Civin, C. I., & Wunderlich, J. R. (1980) · Journal of Immunological Methods · doi:10.1016/0022-1759(80)90066-6 · Cited by 8 · see citing works

Emergence of co-expression in gene regulatory networks

Yin, W., Mendoza, L., Monzón‐Sandoval, J., Urrutia, A. O., & Gutiérrez, H. (2021) · PLoS ONE · doi:10.1371/journal.pone.0247671 · Cited by 72 · see citing works

Relationship between regulatory pattern of gene expression level and gene function

Inoue, M., & Horimoto, K. (2017) · PLoS ONE · doi:10.1371/journal.pone.0177430 · Cited by 16 · see citing works

Regulation of Gene Expression by Nutrients

Dan-na, L. (2006) · China Animal Husbandry & Veterinary Medicine