Cited by 438Neuroscience and Neuropharmacology ResearchMemory and Neural MechanismsNeural dynamics and brain function

The DOI matches its Crossref record; 24 of the 25 references it cites were found in a registry or an index.

Distinct short-term plasticity at two excitatory synapses in the hippocampus

Open access

Salin, Paul A., Scanziani, Massimo, Malenka, Robert C., Nicoll, Roger A.·1996·Proceedings of the National Academy of Sciences

DOI 10.1073/pnas.93.23.13304PMC PMC24088

Open this paper in CoChat — free account

Abstract

A single mossy fiber input contains several release sites and is located on the proximal portion of the apical dendrite of CA3 neurons. It is, therefore, well suited to exert a strong influence on pyramidal cell excitability. Accordingly, the mossy fiber synapse has been referred to as a detonator or teacher synapse in autoassociative network models of the hippocampus. The very low firing rates of granule cells [Jung, M. W. & McNaughton, B. L. (1993) Hippocampus 3, 165-182], which give rise to the mossy fibers, raise the question of how the mossy fiber synapse temporally integrates synaptic activity. We have therefore addressed the frequency dependence of mossy fiber transmission and compared it to associational/commissural synapses in the CA3 region of the hippocampus. Paired pulse facilitation had a similar time course, but was 2-fold greater for mossy fiber synapses. Frequency facilitation, during which repetitive stimulation causes a reversible growth in synaptic transmission, was markedly different at the two synapses. At associational/ commissural synapses facilitation occurred only at frequencies greater than once every 10 s and reached a magnitude of about 125% of control. At mossy fiber synapses, facilitation occurred at frequencies as low as once every 40 s and reached a magnitude of 6-fold. Frequency facilitation was dependent on a rise in intraterminal Ca2+ and activation of Ca2+/calmodulin-dependent kinase II, and was greatly reduced at synapses expressing mossy…

Integrity signals

Registry

Crossref · 10.1073/pnas.93.23.13304

Cites

24 of 24 references verified0 citation errors · 0 not checkable

Statistics

Recomputing p-values needs the paper’s full text.

Claims the paper makes

We couldn’t retrieve this paper’s full text, so its claims and self-check weren’t run. The registry and citation checks still apply.

Claims other papers make about this one

Each is checked against this paper’s own text: does it say what the citing paper says it does?

A synaptic model of memory: long-term potentiation in the hippocampus
Bliss, T. V. P., & Collingridge, G. L. (1993) · Nature · doi:10.1038/361031a0 · Cited by 11,566
Short-Term Synaptic Plasticity
Zucker, R. S. (1989) · Annual Review of Neuroscience · doi:10.1146/annurev.ne.12.030189.000305 · Cited by 1,450
Computational analysis of the role of the hippocampus in memory
Treves, A., & Rolls, E. T. (1994) · Hippocampus · doi:10.1002/hipo.450040319 · Cited by 1,272
Contrasting properties of two forms of long-term potentiation in the hippocampus
Nicoll, R. A., & Malenka, R. C. (1995) · Nature · doi:10.1038/377115a0 · Cited by 861
Self-citation
Spatial selectivity of unit activity in the hippocampal granular layer
Jung, M. W., & McNaughton, B. L. (1993) · Hippocampus · doi:10.1002/hipo.450030209 · Cited by 789
Alien intracellular calcium chelators attenuate neurotransmitter release at the squid giant synapse
Adler, E., Augustine, G., Duffy, S., & Charlton, M. (1991) · The Journal of Neuroscience · doi:10.1523/jneurosci.11-06-01496.1991 · Cited by 624
Mediation of Hippocampal Mossy Fiber Long-Term Potentiation by Cyclic AMP
Weisskopf, M. G., Castillo, P. E., Zalutsky, R. A., & Nicoll, R. A. (1994) · Science · doi:10.1126/science.7916482 · Cited by 618
Self-citation
cAMP contributes to mossy fiber LTP by initiating both a covalently mediated early phase and macromolecular synthesis-dependent late phase
Huang, Y.-Y., Li, X.-C., & Kandel, E. R. (1994) · Cell · doi:10.1016/0092-8674(94)90401-4 · Cited by 490
Temporal Information Transformed into a Spatial Code by a Neural Network with Realistic Properties
Buonomano, D. V., & Merzenich, M. M. (1995) · Science · doi:10.1126/science.7863330 · Cited by 457
Three‐dimensional analysis of the structure and composition of CA3 branched dendritic spines and their synaptic relationships with mossy fiber boutons in the rat hippocampus
Chicurel, M. E., & Harris, K. M. (1992) · Journal of Comparative Neurology · doi:10.1002/cne.903250204 · Cited by 417

Show all 25 references

Research works printed but not linked: 3

C Yamamoto, S Sawada, S Takada Exp Brain Res 51, 128–134 (1983).
L H Hamlyn J Anat 96, 112–126 (1962).
B L McNaughton, L Nadel Neuroscience and Correctionist Theory, eds M A Gluck, D S Rumelhert (Erlbaum), pp. 1–60 (1990).

Sorted by citations

Items 201–300 of 438

Presynaptic regulation of dendrodendritic dopamine transmission
Beckstead, M. J., Ford, C., Phillips, P. E. M., & Williams, J. T. (2007) · European Journal of Neuroscience · doi:10.1111/j.1460-9568.2007.05775.x · Cited by 43
Hippocampal mossy fiber calcium transients are maintained during long-term potentiation and are inhibited by endogenous zinc
Quinta-Ferreira, M. E., & Matias, C. M. (2004) · Brain Research · doi:10.1016/j.brainres.2004.01.013 · Cited by 43
Vesicular Zinc Regulates the Ca 2+ Sensitivity of a Subpopulation of Presynaptic Vesicles at Hippocampal Mossy Fiber Terminals
Lavoie, N., Jeyaraju, D. V., Peralta, M. R., Seress, L., Pellegrini, L., & Tóth, K. (2011) · Journal of Neuroscience · doi:10.1523/jneurosci.4164-11.2011 · Cited by 40
Presynaptic and postsynaptic Ca 2+ and CamKII contribute to long-term potentiation at synapses between individual CA3 neurons
Lu, F., & Hawkins, R. D. (2006) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0508162103 · Cited by 42
Differential regulation of synaptic plasticity of the hippocampal and the hypothalamic inputs to the anterior thalamus
Tsanov, M., Vann, S. D., Erichsen, J. T., Wright, N. F., Aggleton, J. P., & O’Mara, S. M. (2009) · Hippocampus · doi:10.1002/hipo.20749 · Cited by 42
Lactate induces synapse-specific potentiation on CA3 pyramidal cells of rat hippocampus
Herrera‐López, G., Griego, E., & Galván, E. J. (2020) · PLoS ONE · doi:10.1371/journal.pone.0242309 · Cited by 43
Calcium‐dependent mechanisms involved in presynaptic long‐term depression at the hippocampal mossy fibre–CA3 synapse
Kobayashi, K., Manabe, T., & Takahashi, T. (1999) · European Journal of Neuroscience · doi:10.1046/j.1460-9568.1999.00578.x · Cited by 44
Short- and Long-Term Plasticity of the Perforant Path Synapse in Hippocampal Area CA3
McMahon, D. B. T., & Barrionuevo, G. (2002) · Journal of Neurophysiology · doi:10.1152/jn.2002.88.1.528 · Cited by 41
Co‐release of glutamate and GABA from single, identified mossy fibre giant boutons
Beltrán, J. Q., & Gutiérrez, R. (2012) · The Journal of Physiology · doi:10.1113/jphysiol.2012.236372 · Cited by 37
Glutamate release increases during mossy‐CA3 LTP but not during Schaffer‐CA1 LTP
Kawamura, Y., Manita, S., Nakamura, T., Inoue, M., Kudo, Y., & Miyakawa, H. (2004) · European Journal of Neuroscience · doi:10.1111/j.1460-9568.2004.03258.x · Cited by 41
Control of Spike Transfer at Hippocampal Mossy Fiber SynapsesIn Vivoby GABAAand GABABReceptor-Mediated Inhibition
Zucca, S., Griguoli, M., Malézieux, M., Grosjean, N., Carta, M., & Mulle, C. (2016) · Journal of Neuroscience · doi:10.1523/jneurosci.2057-16.2016 · Cited by 39
Action potential counting at giant mossy fiber terminals gates information transfer in the hippocampus
Chamberland, S., Timofeeva, Y., Evstratova, A., Volynski, K. E., & Tóth, K. (2018) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1720659115 · Cited by 40
Doppler Frequency‐Shift Information Processing in WO x ‐Based Memristive Synapse for Auditory Motion Perception
Zeng, T., Wang, Z., Lin, Y., Cheng, Y., Shan, X., Tao, Y., Zhao, X., Xu, H., & Liu, Y. (2023) · Advanced Science · doi:10.1002/advs.202300030 · Cited by 40
Frequency Facilitation at Mossy Fiber–CA3 Synapses of Freely Behaving Rats Is Regulated by Adenosine A1 Receptors
Colitti-Klausnitzer, J., & Manahan‐Vaughan, D. (2008) · Journal of Neuroscience · doi:10.1523/jneurosci.3729-07.2008 · Cited by 39
Short-term Plasticity in Thalamocortical Pathways: Cellular Mechanisms and Functional Roles
Castro‐Alamancos, M. A. (1997) · Reviews in the Neurosciences · doi:10.1515/revneuro.1997.8.2.95 · Cited by 38
Microglia‐derived purines modulate mossy fibre synaptic transmission and plasticity through P2X4 and A1 receptors
George, J., Cunha, R. A., Mulle, C., & Amédée, T. (2016) · European Journal of Neuroscience · doi:10.1111/ejn.13191 · Cited by 42
Neocortical Long-Term Potentiation and Long-Term Depression: Site of Expression Investigated by Infrared-Guided Laser Stimulation
Eder, M., Zieglgänsberger, W., & Dodt, H. (2002) · Journal of Neuroscience · doi:10.1523/jneurosci.22-17-07558.2002 · Cited by 38
Neuroligin 1 modulates striatal glutamatergic neurotransmission in a pathway and NMDAR subunit-specific manner
Espinosa, F., Xuan, Z., Liu, S., & Powell, C. M. (2015) · Frontiers in Synaptic Neuroscience · doi:10.3389/fnsyn.2015.00011 · Cited by 37
Calcium and Activity-Dependent Synaptic Plasticity
Hanse, E., & Konnerth, A. (1998) · Springer eBooks · doi:10.1007/978-1-4899-1901-4_16 · Cited by 38
Silicon-Nanomembrane-Based Broadband Synaptic Phototransistors for Neuromorphic Vision
Wang, Y., Yin, L., Huang, S., Xiao, R., Zhang, Y., Li, D., Pi, X., & Yang, D. (2023) · Nano Letters · doi:10.1021/acs.nanolett.3c01853 · Cited by 36
Isolated Primary Blast Inhibits Long-Term Potentiation in Organotypic Hippocampal Slice Cultures
Vogel, E. W., Effgen, G. B., Patel, T. P., Meaney, D. F., Bass, C. R., & Morrison, B. (2015) · Journal of Neurotrauma · doi:10.1089/neu.2015.4045 · Cited by 37
Increased vesicle fusion competence underlies long-term potentiation at hippocampal mossy fiber synapses
Fukaya, R., Hirai, H., Sakamoto, H., Hashimotodani, Y., Hirose, K., & Sakaba, T. (2023) · Science Advances · doi:10.1126/sciadv.add3616 · Cited by 36
Dentate gyrus granule cell firing patterns can induce mossy fiber long‐term potentiation in vitro
Mistry, R. B., Dennis, S. H., Frerking, M. E., & Mellor, J. R. (2010) · Hippocampus · doi:10.1002/hipo.20815 · Cited by 35
Differential roles of Ca 2+ /calmodulin-dependent kinases in posttetanic potentiation at input selective glutamatergic pathways
Wang, D., & Maler, L. (1998) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.95.12.7133 · Cited by 36
Dopamine D1/D5, But not D2/D3, Receptor Dependency of Synaptic Plasticity at Hippocampal Mossy Fiber Synapses that Is Enabled by Patterned Afferent Stimulation, or Spatial Learning
Hagena, H., & Manahan‐Vaughan, D. (2016) · Frontiers in Synaptic Neuroscience · doi:10.3389/fnsyn.2016.00031 · Cited by 34
Impaired expression and function of group II metabotropic glutamate receptors in pilocarpine-treated chronically epileptic rats
Garrido-Sanabria, E. R., Otalora, L. F. P., Arshadmansab, M. F., Herrera, B., Francisco, S., & Ermolinsky, B. S. (2008) · Brain Research · doi:10.1016/j.brainres.2008.08.084 · Cited by 35
mGluRs Modulate Strength and Timing of Excitatory Transmission in Hippocampal Area CA3
Cosgrove, K. E., Galván, E. J., Barrionuevo, G., & Meriney, S. D. (2011) · Molecular Neurobiology · doi:10.1007/s12035-011-8187-z · Cited by 36
Altered synaptic plasticity in the mossy fibre pathway of transgenic mice expressing mutant amyloid precursor protein
Witton, J., Brown, J. T., Jones, M. W., & Randall, A. D. (2010) · Molecular Brain · doi:10.1186/1756-6606-3-32 · Cited by 35
Afferent‐specific properties of interneuron synapses underlie selective long‐term regulation of feedback inhibitory circuits in CA1 hippocampus
Croce, A., Pelletier, J. G., Tartas, M., & Lacaille, J. (2010) · The Journal of Physiology · doi:10.1113/jphysiol.2010.189316 · Cited by 34
Frequency Facilitation at Mossy Fiber-CA3 Synapses of Freely Behaving Rats Contributes to the Induction of Persistent LTD via an Adenosine-A1 Receptor-Regulated Mechanism
Hagena, H., & Manahan‐Vaughan, D. (2009) · Cerebral Cortex · doi:10.1093/cercor/bhp184 · Cited by 36
Short-Term Depression of Sprouted Mossy Fiber Synapses from Adult-Born Granule Cells
Hendricks, W. D., Chen, Y., Bensen, A. L., Westbrook, G. L., & Schnell, E. (2017) · Journal of Neuroscience · doi:10.1523/jneurosci.0761-17.2017 · Cited by 31
Bilateral enhancement of excitation via up-regulation of vesicular glutamate transporter subtype 1, not subtype 2, immunoreactivity in the unilateral hypoxic epilepsy model
Kim, D., Kwak, S., Kim, J., Won, M. H., Choi, H., Song, H., Kwon, O., Kim, Y.-I., Choi, S., & Kang, T. (2005) · Brain Research · doi:10.1016/j.brainres.2005.06.081 · Cited by 35
Differentiation in the protein synthesis-dependency of persistent synaptic plasticity in mossy fiber and associational/commissural CA3 synapses in vivo
Hagena, H., & Manahan‐Vaughan, D. (2013) · Frontiers in Integrative Neuroscience · doi:10.3389/fnint.2013.00010 · Cited by 34
Realization of Biomimetic Synaptic Functions in a One-Cell Organic Resistive Switching Device Using the Diffusive Parameter of Conductive Filaments
Lee, S., Park, H., Kim, M., Kim, M., Park, B., & Lee, S.-D. (2020) · ACS Applied Materials & Interfaces · doi:10.1021/acsami.0c15519 · Cited by 34
A Combined Optogenetic-Knockdown Strategy Reveals a Major Role of Tomosyn in Mossy Fiber Synaptic Plasticity
Ben‐Simon, Y., Rodenas-Ruano, A., Alviña, K., Lam, A. D., Stuenkel, E. L., Castillo, P. E., & Ashery, U. (2015) · Cell Reports · doi:10.1016/j.celrep.2015.06.037 · Cited by 34
The single place fields of CA3 cells: A two‐stage transformation from grid cells
de Almeida, L., Idiart, M., & Lisman, J. E. (2010) · Hippocampus · doi:10.1002/hipo.20882 · Cited by 32
A delayed response enhancement during hippocampal presynaptic plasticity in mice
Jensen, V., Walaas, S. I., Hilfiker, S., Ruiz, A., & Hvalby, Ø. (2007) · The Journal of Physiology · doi:10.1113/jphysiol.2007.131300 · Cited by 33
PGE 2 -EP3 signaling pathway impairs hippocampal presynaptic long-term plasticity in a mouse model of Alzheimer's disease
Maingret, V., Barthet, G., Deforges, S., Jiang, N., Mulle, C., & Amédée, T. (2016) · Neurobiology of Aging · doi:10.1016/j.neurobiolaging.2016.10.012 · Cited by 30
Flexible and transparent memristive synapse based on polyvinylpyrrolidone/N-doped carbon quantum dot nanocomposites for neuromorphic computing
Zeng, T., Yang, Z. C., Liang, J., Lin, Y., Cheng, Y., Hu, X., Zhao, X., Wang, Z., Xu, H., & Liu, Y. (2021) · Nanoscale Advances · doi:10.1039/d1na00152c · Cited by 31
Genetic deletion of melanin‐concentrating hormone neurons impairs hippocampal short‐term synaptic plasticity and hippocampal‐dependent forms of short‐term memory
Barillier, L. L., Léger, L., Luppi, P., Fort, P., Malleret, G., & Salin, P. A. (2015) · Hippocampus · doi:10.1002/hipo.22442 · Cited by 31
Self-citation
Internal representation of hippocampal neuronal population spans a time-distance continuum
Haimerl, C., Angulo‐García, D., Villette, V., Reichinnek, S., Torcini, A., Cossart, R., & Malvache, A. (2019) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1718518116 · Cited by 30
Locomotor activity correlates with modifications of hippocampal mossy fibre synaptic transmission
Kobayashi, K., Ikeda, Y., & Suzuki, H. (2006) · European Journal of Neuroscience · doi:10.1111/j.1460-9568.2006.05079.x · Cited by 29
Two Forms of Hippocampal Long-Term Depression, the Counterpart of Long-Term Potentiation
Manabe, T. (1997) · Reviews in the Neurosciences · doi:10.1515/revneuro.1997.8.3-4.179 · Cited by 29
Natural Spike Trains Trigger Short- and Long-Lasting Dynamics at Hippocampal Mossy Fiber Synapses in Rodents
Gundlfinger, A., Breustedt, J., Sullivan, D. W., & Schmitz, D. (2010) · PLoS ONE · doi:10.1371/journal.pone.0009961 · Cited by 28
Single Bursts of Individual Granule Cells Functionally Rearrange Feedforward Inhibition
Neubrandt, M., Oláh, V. J., Brunner, J., Marosi, E. L., Soltész, I., & Szabadics, J. (2018) · Journal of Neuroscience · doi:10.1523/jneurosci.1595-17.2018 · Cited by 28
Subcellular patch-clamp techniques for single-bouton stimulation and simultaneous pre- and postsynaptic recording at cortical synapses
Vandael, D., Okamoto, Y., Borges-Merjane, C., Vargas-Barroso, V., Suter, B. A., & Jonas, P. (2021) · Nature Protocols · doi:10.1038/s41596-021-00526-0 · Cited by 28
Differential modulation of short‐term synaptic dynamics by long‐term potentiation at mouse hippocampal mossy fibre synapses
Gundlfinger, A., Leibold, C., Gebert, K., Moisel, M., Schmitz, D., & Kempter, R. (2007) · The Journal of Physiology · doi:10.1113/jphysiol.2007.143925 · Cited by 27
Galanin Alters GABAergic Neurotransmission in the Dorsal Raphe Nucleus
Sharkey, L. M., Madamba, S. G., Siggins, G. R., & Bartfai, T. (2007) · Neurochemical Research · doi:10.1007/s11064-007-9524-5 · Cited by 28
Aβ oligomers from human brain impair mossy fiber LTP in CA3 of hippocampus, but activating cAMP-PKA and cGMP-PKG prevents this
Jin, S., Liu, L., Li, S., Meunier, A. L., & Selkoe, D. J. (2022) · Neurobiology of Disease · doi:10.1016/j.nbd.2022.105816 · Cited by 27
Impaired development of hippocampal mossy fibre synapses in mouse mutants for the presynaptic scaffold protein Bassoon
Lanore, F., Blanchet, C., Fejtová, A., Pinheiro, P. S., Richter, K., Balschun, D., Gundelfinger, E., & Mulle, C. (2010) · Journal of Physiology · doi:10.1113/jphysiol.2009.184929 · Cited by 24
Photolysis of Postsynaptic Caged Ca2+Can Potentiate and Depress Mossy Fiber Synaptic Responses in Rat Hippocampal CA3 Pyramidal Neurons
Wang, J., Yeckel, M. F., Johnston, D., & Zucker, R. S. (2004) · Journal of Neurophysiology · doi:10.1152/jn.01073.2003 · Cited by 29
Mitochondrial Ca2+ uniporter haploinsufficiency enhances long-term potentiation at hippocampal mossy fibre synapses
Devine, M. J., Szulc, B. R., Howden, J. H., López‐Doménech, G., Ruiz, A. J., & Kittler, J. T. (2022) · Journal of Cell Science · doi:10.1242/jcs.259823 · Cited by 27
Short-Term Plasticity of Kainate Receptor-Mediated EPSCs Induced by NMDA Receptors at Hippocampal Mossy Fiber Synapses
Rebola, N., Sachidhanandam, S., Perrais, D., Cunha, R. A., & Mulle, C. (2007) · Journal of Neuroscience · doi:10.1523/jneurosci.5182-06.2007 · Cited by 26
Temporal compression mediated by short-term synaptic plasticity
Leibold, C., Gundlfinger, A., Schmidt, R., Thurley, K., Schmitz, D., & Kempter, R. (2008) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0708711105 · Cited by 26
Ionotropic receptors at hippocampal mossy fibers: roles in axonal excitability, synaptic transmission, and plasticity
Ruiz, A. J., & Kullmann, D. M. (2013) · Frontiers in Neural Circuits · doi:10.3389/fncir.2012.00112 · Cited by 25
Zeolite‐Based Memristive Synapse with Ultralow Sub‐10‐fJ Energy Consumption for Neuromorphic Computation
Zeng, T., Zou, X., Wang, Z., Yu, G., Yang, Z. C., Rong, H., Zhang, C., Xu, H., Lin, Y., Zhao, X., et al. (2021) · Small · doi:10.1002/smll.202006662 · Cited by 25
AMPA receptor subunits define properties of state-dependent synaptic plasticity
Emond, M. R., Montgomery, J. M., Huggins, M. L., Hanson, J. E., Mao, L., Huganir, R. L., & Madison, D. V. (2010) · The Journal of Physiology · doi:10.1113/jphysiol.2010.187229 · Cited by 26
mGlu5 Acts As a Switch for Opposing Forms of Synaptic Plasticity at Mossy Fiber–CA3 and Commissural Associational–CA3 Synapses
Hagena, H., & Manahan‐Vaughan, D. (2015) · Journal of Neuroscience · doi:10.1523/jneurosci.3417-14.2015 · Cited by 26
Short-Term Facilitation at a Detonator Synapse Requires the Distinct Contribution of Multiple Types of Voltage-Gated Calcium Channels
Chamberland, S., Evstratova, A., & Tóth, K. (2017) · Journal of Neuroscience · doi:10.1523/jneurosci.0159-17.2017 · Cited by 24
Excitatory Synaptic Input to Hilar Mossy Cells under Basal and Hyperexcitable Conditions
Hedrick, T. P., Nobis, W. P., Foote, K. M., Ishii, T., Chetkovich, D. M., & Swanson, G. T. (2017) · eNeuro · doi:10.1523/eneuro.0364-17.2017 · Cited by 24
Attenuated Plasticity of Postsynaptic Kainate Receptors in Hippocampal CA3 Pyramidal Neurons
Ito, K., Contractor, A., & Swanson, G. T. (2004) · Journal of Neuroscience · doi:10.1523/jneurosci.1302-04.2004 · Cited by 25
Neuronal adaptation involves rapid expansion of the action potential initiation site
Scott, R. S., Henneberger, C., Padmashri, R., Anders, S., Jensen, T. P., & Rusakov, D. A. (2014) · Nature Communications · doi:10.1038/ncomms4817 · Cited by 25
Silicon-based optoelectronic synaptic devices*
Yin, L., Pi, X., & Yang, D. (2020) · Chinese Physics B · doi:10.1088/1674-1056/ab973f · Cited by 24
Synapsin- and Actin-Dependent Frequency Enhancement in Mouse Hippocampal Mossy Fiber Synapses
Owe, S. G., Jensen, V., Evergren, E., Ruiz, A. J., Shupliakov, O., Kullmann, D. M., Storm‐Mathisen, J., Walaas, S. I., Hvalby, Ø., & Bergersen, L. H. (2008) · Cerebral Cortex · doi:10.1093/cercor/bhn101 · Cited by 26
Improved switching and synapse characteristics using PEALD SiO2 thin film in Cu/SiO2/ZrO2/Pt device
Lee, D.-H., Sokolov, A., Ku, B., Jeon, Y.-R., Kim, D. H., Kim, H. T., Kim, G. H., & Choi, C. (2021) · Applied Surface Science · doi:10.1016/j.apsusc.2021.149140 · Cited by 20
Mesencephalic astrocyte-derived neurotrophic factor enhances nigral γ-aminobutyric acid release
Zhou, C., Xiao, C., Commissiong, J. W., Krnjević, K., & Ye, J. H. (2006) · Neuroreport · doi:10.1097/01.wnr.0000201504.23255.bc · Cited by 23
Characterization of Tissue Plasminogen Activator Expression and Trafficking in the Adult Murine Brain
Stevenson, T. K., & Lawrence, D. A. (2018) · eNeuro · doi:10.1523/eneuro.0119-18.2018 · Cited by 22
Modulation of Short-Term Plasticity in the Corticothalamic Circuit by Group III Metabotropic Glutamate Receptors
Lee, C. K., & Huguenard, J. R. (2014) · Journal of Neuroscience · doi:10.1523/jneurosci.1477-13.2014 · Cited by 22
Synapse-specific compartmentalization of signaling cascades for LTP induction in CA3 interneurons
Galván, E. J., Pérez-Rosello, T., Gómez-Lira, G., Lara, E., Gutiérrez, R., & Barrionuevo, G. (2015) · Neuroscience · doi:10.1016/j.neuroscience.2015.01.024 · Cited by 21
A review of MXene memristors and their applications
Hota, M. K., Pazos, S. M., Lanza, M., & Alshareef, H. N. (2025) · Materials Science and Engineering R Reports · doi:10.1016/j.mser.2025.100983 · Cited by 21
Involvement of the primate specific gene G72 in schizophrenia: From genetic studies to pathomechanisms
Drews, E., Otte, D.-M., & Zimmer, A. (2012) · Neuroscience & Biobehavioral Reviews · doi:10.1016/j.neubiorev.2012.10.009 · Cited by 24
Reexamination of the role of hyperpolarization-activated cation channels in short- and long-term plasticity at hippocampal mossy fiber synapses
Huang, C., & Hsu, K. (2003) · Neuropharmacology · doi:10.1016/s0028-3908(03)00098-4 · Cited by 21
TEA-induced long-term potentiation at hippocampal mossy fiber-CA3 synapses: Characteristics of its induction and expression
Suzuki, E., & Okada, T. (2008) · Brain Research · doi:10.1016/j.brainres.2008.09.101 · Cited by 22
Differences in amplitude–voltage relations between minimal and composite mossy fibre responses of rat CA3 hippocampal neurons support the existence of intrasynaptic ephaptic feedback in large synapses
Kasyanov, A. M., Maximov, V. V., Byzov, A. L., Berretta, N., Sokolov, M., Gasparini, S., Cherubini, E., Reymann, K. G., & Voronin, L. L. (2000) · Neuroscience · doi:10.1016/s0306-4522(00)00366-3 · Cited by 21
Transsynaptic modulation of presynaptic short-term plasticity in hippocampal mossy fiber synapses
Vandael, D. H. F., Okamoto, Y., & Jónás, P. (2021) · Nature Communications · doi:10.1038/s41467-021-23153-5 · Cited by 20
Dynamic resistive switching devices for neuromorphic computing
Wu, Y., Wang, X., & Lu, W. D. (2021) · Semiconductor Science and Technology · doi:10.1088/1361-6641/ac41e4 · Cited by 21
Juxtacellular opto-tagging of hippocampal CA1 neurons in freely moving mice
Ding, L., Balsamo, G., Chen, H., Blanco-Hernández, E., Zouridis, I. S., Naumann, R. K., Preston‐Ferrer, P., & Burgalossi, A. (2022) · eLife · doi:10.7554/elife.71720 · Cited by 20
Primary afferent synaptic responses recorded from trigeminal caudal neurons in a mandibular nerve—brainstem preparation of neonatal rats
Onodera, K., Hamba, M., & Takahashi, T. (2000) · The Journal of Physiology · doi:10.1111/j.1469-7793.2000.00503.x · Cited by 20
Dynamics of excitatory transmitter release: analysis of synaptic responses in CA3 hippocampal neurons after repetitive stimulation of afferent fibers.
Canepari, M., & Cherubini, E. (1998) · Journal of Neurophysiology · doi:10.1152/jn.1998.79.4.1977 · Cited by 23
Short- and Long-Lasting Consequences of In Vivo Nicotine Treatment on Hippocampal Excitability
Penton, R. E., Quick, M. W., & Lester, R. A. J. (2011) · The Journal of Neuroscience · doi:10.1523/jneurosci.4362-10.2011 · Cited by 19
Hippocampal and cerebellar mossy fibre boutons – same name, different function
Delvendahl, I., Rings, A., Ritzau‐Jost, A., & Hallermann, S. (2013) · The Journal of Physiology · doi:10.1113/jphysiol.2012.248294 · Cited by 19
The Role of mGlu Receptors in Hippocampal Plasticity Deficits in Neurological and Psychiatric Disorders: Implications for Allosteric Modulators as Novel Therapeutic Strategies
Senter, R. K., Ghoshal, A., Walker, A. G., Xiang, Z., Niswender, C. M., & Conn, P. J. (2016) · Current Neuropharmacology · doi:10.2174/1570159x13666150421003225 · Cited by 20
Presynaptic Facilitation of Synaptic Transmission in the Hippocampus
Capogna, M. (1998) · Pharmacology & Therapeutics · doi:10.1016/s0163-7258(97)00162-9 · Cited by 18
Inhibition of long‐term potentiation by valproic acid through modulation of cyclic AMP
Chang, P., Chandler, K. E., Williams, R. S. B., & Walker, M. C. (2009) · Epilepsia · doi:10.1111/j.1528-1167.2009.02412.x · Cited by 19
Theta‐paced flickering between place‐cell maps in the hippocampus: A model based on short‐term synaptic plasticity
Mark, S., Romani, S., Ježek, K., & Tsodyks, M. V. (2017) · Hippocampus · doi:10.1002/hipo.22743 · Cited by 18
Diurnal inhibition of NMDA‐EPSCs at rat hippocampal mossy fibre synapses through orexin‐2 receptors
Perin, M., Longordo, F., Massonnet, C., Welker, E., & Lüthi, A. (2014) · The Journal of Physiology · doi:10.1113/jphysiol.2014.272757 · Cited by 18
Synaptic vesicle dynamics in the mossy fiber-CA3 presynaptic terminals of mouse hippocampus
Suyama, S., Hikima, T., Sakagami, H., Ishizuka, T., & Yawo, H. (2007) · Neuroscience Research · doi:10.1016/j.neures.2007.08.019 · Cited by 18
Persistent but Labile Synaptic Plasticity at Excitatory Synapses
Pradier, B., Lanning, K. M., Taljan, K. T., Feuille, C. J., Nagy, M. A., & Kauer, J. A. (2018) · Journal of Neuroscience · doi:10.1523/jneurosci.2772-17.2018 · Cited by 18
Differences in kainate receptor involvement in hippocampal mossy fibre long-term potentiation depending on slice orientation
Sherwood, J. L., Amici, M., Amici-Dargan, S., Culley, G. R., Fitzjohn, S. M., Jane, D. E., Collingridge, G. L., Lodge, D., & Bortolotto, Z. A. (2012) · Neurochemistry International · doi:10.1016/j.neuint.2012.04.021 · Cited by 17
Hardware Realization of the Pattern Recognition with an Artificial Neuromorphic Device Exhibiting a Short-Term Memory
Przyczyna, D., Lis, M., Pilarczyk, K., & Szacilowski, K. T. (2019) · Molecules · doi:10.3390/molecules24152738 · Cited by 17
Brief ischemia causes long‐term depression in midbrain dopamine neurons
Singh, V., Carman, M., Roeper, J., & Bonci, A. (2007) · European Journal of Neuroscience · doi:10.1111/j.1460-9568.2007.05781.x · Cited by 16
Regional differences in GABAergic modulation for TEA-induced synaptic plasticity in rat hippocampal CA1, CA3 and dentate gyrus
Suzuki, E., & Okada, T. (2007) · Neuroscience Research · doi:10.1016/j.neures.2007.06.1472 · Cited by 17
Presynaptic cAMP-PKA-mediated potentiation induces reconfiguration of synaptic vesicle pools and channel-vesicle coupling at hippocampal mossy fiber boutons
Kim, O., Okamoto, Y., Kaufmann, W. A., Brose, N., Shigemoto, R., & Jonas, P. (2024) · PLOS Biology · doi:10.1371/journal.pbio.3002879 · Cited by 15
“Second, it has a unique extent of presynaptic plasticity, including facilitation, post-tetanic potentiation (PTP) [21], and long-term potentiation (LTP) [27].”
The Two Sides of Hippocampal Mossy Fiber Plasticity
Kerr, A. M., & Jónás, P. (2008) · Neuron · doi:10.1016/j.neuron.2007.12.015 · Cited by 16
Functional compartmentalisation and regulation of postsynaptic Ca2+ transients in inhibitory interneurons
Camiré, O., & Topolnik, L. (2012) · Cell Calcium · doi:10.1016/j.ceca.2012.05.001 · Cited by 15
Pumilio2regulates synaptic plasticity via translational repression of synaptic receptors in mice
Dong, H., Zhu, M., Meng, L., Ding, Y., Ding, Y., Zhang, S., Qiang, W., Fisher, D. W., & Xu, E. Y. (2018) · Oncotarget · doi:10.18632/oncotarget.24345 · Cited by 15
Normalized unitary synaptic signaling of the hippocampus and entorhinal cortex predicted by deep learning of experimental recordings
Moradi, K., Aldarraji, Z., Luthra, M., Madison, G. P., & Ascoli, G. A. (2022) · Communications Biology · doi:10.1038/s42003-022-03329-5 · Cited by 14
Stem cell factor modulates paired-pulse facilitation and long-term potentiation in the hippocampal mossy fiber–CA3 pathway in mice
Kondo, T., Katafuchi, T., & Hori, T. (2002) · Brain Research · doi:10.1016/s0006-8993(02)02879-2 · Cited by 14
Mechanistic insights into cAMP-mediated presynaptic potentiation at hippocampal mossy fiber synapses
Fukaya, R., Miyano, R., Hirai, H., & Sakaba, T. (2023) · Frontiers in Cellular Neuroscience · doi:10.3389/fncel.2023.1237589 · Cited by 13
Evolutionary conservation of hippocampal mossy fiber synapse properties
Pelkey, K. A., Vargish, G. A., Pellegrini, L. V., Calvigioni, D., Chapeton, J. I., Yuan, X. Q., Hunt, S., Cummins, A. C., Eldridge, M. A. G., Pickel, J. M., et al. (2023) · Neuron · doi:10.1016/j.neuron.2023.09.005 · Cited by 16

Authors: Salin, P. A., Scanziani, M., Malenka, R. C., & Nicoll, R. A.
Affiliations: University of California, San Francisco (US)
ORCID: Salin, Paul A.
Scanziani, Massimo
Malenka, Robert C.
Nicoll, Roger A.
Venue: Proceedings of the National Academy of Sciences
Publisher: National Academy of Sciences
Published: 1996-11-12
Volume: 93
Issue: 23
Pages: 13304-13309
ISSN: 0027-8424 (ISSN-L)
1091-6490
DOI: 10.1073/pnas.93.23.13304
PMC: PMC24088
OpenAlex: W2055775269
Cited by: 438
References: 25
Citations by year: 2026: 6 · 2025: 14 · 2024: 13 · 2023: 19 · 2022: 12 · 2021: 17 · 2020: 17 · 2019: 15 · 2018: 20 · 2017: 15 · 2016: 13 · 2015: 11 · 2014: 18 · 2013: 15 · 2012: 10
FWCI: 4.06
Type: journal article
Language: en
Open access: green
europepmc.org
Locations: Proceedings of the National Academy of Sciences (publishedVersion)
Europe PMC (PubMed Central) (publishedVersion)
PubMed Central (publishedVersion)
PubMed (publishedVersion)
Topics: Life Sciences › Neuroscience › Cellular and Molecular Neuroscience › Neuroscience and Neuropharmacology Research
Life Sciences › Neuroscience › Cognitive Neuroscience › Memory and Neural Mechanisms
Life Sciences › Neuroscience › Cognitive Neuroscience › Neural dynamics and brain function
Keywords: mossy fiber synapses, short-term plasticity, frequency facilitation, paired-pulse facilitation, CA3 pyramidal cells, granule cells, long-term potentiation, synaptic integration, hippocampus
MeSH terms: Animals, Calcium, Egtazic Acid, Evoked Potentials, Guinea Pigs, Hippocampus, Magnesium, Nerve Fibers, Neuronal Plasticity, Neurons, Quinoxalines, Synapses, Time Factors, 4-Aminopyridine, Receptors, N-Methyl-D-Aspartate, Long-Term Potentiation, Calcium-Calmodulin-Dependent Protein Kinases, Pyramidal Cells, Receptors, AMPA, 6-Cyano-7-nitroquinoxaline-2,3-dione, Calcium-Calmodulin-Dependent Protein Kinase Type 2, In Vitro Techniques

About these checks

Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.

Statistics and arithmetic are recomputed, not judged.

Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.

What counts as a claim ›How we measure confidence ›How we check this ›

Are you an author, or do you see a problem with this page? Request a review

Distinct short-term plasticity at two excitatory synapses in the hippocampus

Abstract

Overview

Integrity signals

Verification

Claims the paper makes

Claims other papers make about this one

Citations

Cites

Cited by

Related

Metadata

Record

About these checks