Cited by 438Neuroscience and Neuropharmacology ResearchMemory and Neural MechanismsNeural dynamics and brain function

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Distinct short-term plasticity at two excitatory synapses in the hippocampus

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Salin, Paul A., Scanziani, Massimo, Malenka, Robert C., Nicoll, Roger A.·1996·Proceedings of the National Academy of Sciences

DOI 10.1073/pnas.93.23.13304PMC PMC24088

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Abstract

A single mossy fiber input contains several release sites and is located on the proximal portion of the apical dendrite of CA3 neurons. It is, therefore, well suited to exert a strong influence on pyramidal cell excitability. Accordingly, the mossy fiber synapse has been referred to as a detonator or teacher synapse in autoassociative network models of the hippocampus. The very low firing rates of granule cells [Jung, M. W. & McNaughton, B. L. (1993) Hippocampus 3, 165-182], which give rise to the mossy fibers, raise the question of how the mossy fiber synapse temporally integrates synaptic activity. We have therefore addressed the frequency dependence of mossy fiber transmission and compared it to associational/commissural synapses in the CA3 region of the hippocampus. Paired pulse facilitation had a similar time course, but was 2-fold greater for mossy fiber synapses. Frequency facilitation, during which repetitive stimulation causes a reversible growth in synaptic transmission, was markedly different at the two synapses. At associational/ commissural synapses facilitation occurred only at frequencies greater than once every 10 s and reached a magnitude of about 125% of control. At mossy fiber synapses, facilitation occurred at frequencies as low as once every 40 s and reached a magnitude of 6-fold. Frequency facilitation was dependent on a rise in intraterminal Ca2+ and activation of Ca2+/calmodulin-dependent kinase II, and was greatly reduced at synapses expressing mossy…

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A synaptic model of memory: long-term potentiation in the hippocampus
Bliss, T. V. P., & Collingridge, G. L. (1993) · Nature · doi:10.1038/361031a0 · Cited by 11,566
Short-Term Synaptic Plasticity
Zucker, R. S. (1989) · Annual Review of Neuroscience · doi:10.1146/annurev.ne.12.030189.000305 · Cited by 1,450
Computational analysis of the role of the hippocampus in memory
Treves, A., & Rolls, E. T. (1994) · Hippocampus · doi:10.1002/hipo.450040319 · Cited by 1,272
Contrasting properties of two forms of long-term potentiation in the hippocampus
Nicoll, R. A., & Malenka, R. C. (1995) · Nature · doi:10.1038/377115a0 · Cited by 861
Self-citation
Spatial selectivity of unit activity in the hippocampal granular layer
Jung, M. W., & McNaughton, B. L. (1993) · Hippocampus · doi:10.1002/hipo.450030209 · Cited by 789
Alien intracellular calcium chelators attenuate neurotransmitter release at the squid giant synapse
Adler, E., Augustine, G., Duffy, S., & Charlton, M. (1991) · The Journal of Neuroscience · doi:10.1523/jneurosci.11-06-01496.1991 · Cited by 624
Mediation of Hippocampal Mossy Fiber Long-Term Potentiation by Cyclic AMP
Weisskopf, M. G., Castillo, P. E., Zalutsky, R. A., & Nicoll, R. A. (1994) · Science · doi:10.1126/science.7916482 · Cited by 618
Self-citation
cAMP contributes to mossy fiber LTP by initiating both a covalently mediated early phase and macromolecular synthesis-dependent late phase
Huang, Y.-Y., Li, X.-C., & Kandel, E. R. (1994) · Cell · doi:10.1016/0092-8674(94)90401-4 · Cited by 490
Temporal Information Transformed into a Spatial Code by a Neural Network with Realistic Properties
Buonomano, D. V., & Merzenich, M. M. (1995) · Science · doi:10.1126/science.7863330 · Cited by 457
Three‐dimensional analysis of the structure and composition of CA3 branched dendritic spines and their synaptic relationships with mossy fiber boutons in the rat hippocampus
Chicurel, M. E., & Harris, K. M. (1992) · Journal of Comparative Neurology · doi:10.1002/cne.903250204 · Cited by 417

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C Yamamoto, S Sawada, S Takada Exp Brain Res 51, 128–134 (1983).
L H Hamlyn J Anat 96, 112–126 (1962).
B L McNaughton, L Nadel Neuroscience and Correctionist Theory, eds M A Gluck, D S Rumelhert (Erlbaum), pp. 1–60 (1990).

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Authors: Salin, P. A., Scanziani, M., Malenka, R. C., & Nicoll, R. A.
Affiliations: University of California, San Francisco (US)
ORCID: Salin, Paul A.
Scanziani, Massimo
Malenka, Robert C.
Nicoll, Roger A.
Venue: Proceedings of the National Academy of Sciences
Publisher: National Academy of Sciences
Published: 1996-11-12
Volume: 93
Issue: 23
Pages: 13304-13309
ISSN: 0027-8424 (ISSN-L)
1091-6490
DOI: 10.1073/pnas.93.23.13304
PMC: PMC24088
OpenAlex: W2055775269
Cited by: 438
References: 25
Citations by year: 2026: 6 · 2025: 14 · 2024: 13 · 2023: 19 · 2022: 12 · 2021: 17 · 2020: 17 · 2019: 15 · 2018: 20 · 2017: 15 · 2016: 13 · 2015: 11 · 2014: 18 · 2013: 15 · 2012: 10
FWCI: 4.06
Type: journal article
Language: en
Open access: green
europepmc.org
Locations: Proceedings of the National Academy of Sciences (publishedVersion)
Europe PMC (PubMed Central) (publishedVersion)
PubMed Central (publishedVersion)
PubMed (publishedVersion)
Topics: Life Sciences › Neuroscience › Cellular and Molecular Neuroscience › Neuroscience and Neuropharmacology Research
Life Sciences › Neuroscience › Cognitive Neuroscience › Memory and Neural Mechanisms
Life Sciences › Neuroscience › Cognitive Neuroscience › Neural dynamics and brain function
Keywords: mossy fiber synapses, short-term plasticity, frequency facilitation, paired-pulse facilitation, CA3 pyramidal cells, granule cells, long-term potentiation, synaptic integration, hippocampus
MeSH terms: Animals, Calcium, Egtazic Acid, Evoked Potentials, Guinea Pigs, Hippocampus, Magnesium, Nerve Fibers, Neuronal Plasticity, Neurons, Quinoxalines, Synapses, Time Factors, 4-Aminopyridine, Receptors, N-Methyl-D-Aspartate, Long-Term Potentiation, Calcium-Calmodulin-Dependent Protein Kinases, Pyramidal Cells, Receptors, AMPA, 6-Cyano-7-nitroquinoxaline-2,3-dione, Calcium-Calmodulin-Dependent Protein Kinase Type 2, In Vitro Techniques

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Distinct short-term plasticity at two excitatory synapses in the hippocampus

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