Regulatory evolution and the origin of the bilaterians
Open accessAbstract
The adult body plan of bilaterians is achieved by imposing regional specifications on pluripotential cells. The establishment of spatial domains is governed in part by regulating expression of transcription factors. The key to understanding bilaterian evolution is contingent on our understanding of how the regulation of these transcription factors influenced bilaterian stem-group evolution.
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The bilaterian-cnidarian ancestor likely lived well before the Cambrian.
“Molecular and morphological phylogenies agree that the bilaterian stem group emerged from a common ancestor of bilaterians and cnidarians, which probably existed much deeper in time (Peterson and Eernisse, 2001;Medina et al., 2001;Peterson and Davidson, 2000).”
From Precambrian Animal Life: Probable Developmental and Adult Cnidarian Forms from Southwest China (2002) · cites this paper as Peterson and Davidson, 2000
Both molecular and morphological phylogenies indicate that the bilaterian stem lineage arose from an ancestor shared with cnidarians.
“Molecular and morphological phylogenies agree that the bilaterian stem group emerged from a common ancestor of bilaterians and cnidarians, which probably existed much deeper in time (Peterson and Eernisse, 2001;Medina et al., 2001;Peterson and Davidson, 2000).”
From Precambrian Animal Life: Probable Developmental and Adult Cnidarian Forms from Southwest China (2002) · cites this paper as Peterson and Davidson, 2000
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- Authors
- Peterson, K. J., & Davidson, E. H.
- Affiliations
- California Institute of Technology (US)
- Corresponding author
- Davidson, Eric H.
- ORCID
- Peterson, Kevin J.
- Venue
- Proceedings of the National Academy of Sciences
- Publisher
- National Academy of Sciences
- Published
- 2000-04-25
- Volume
- 97
- Issue
- 9
- Pages
- 4430-4433
- ISSN
- 0027-8424 (ISSN-L)
- 1091-6490
- PMC
- PMC34315
- OpenAlex
- W2147483153
- Cited by
- 139
- References
- 43
- Citations by year
- 2025: 4 · 2024: 2 · 2023: 4 · 2022: 3 · 2021: 1 · 2020: 3 · 2019: 8 · 2017: 1 · 2016: 4 · 2015: 4 · 2014: 4 · 2013: 4 · 2012: 4
- FWCI
- 4.58
- Type
- journal article
- Language
- en
- Open access
- green
- europepmc.org
- Locations
- Proceedings of the National Academy of Sciences (publishedVersion)
- Europe PMC (PubMed Central) (publishedVersion)
- PubMed Central (publishedVersion)
- PubMed (publishedVersion)
- CaltechAUTHORS (California Institute of Technology) (submittedVersion)
- Topics
- Life Sciences › Biochemistry, Genetics and Molecular Biology › Molecular Biology › Developmental Biology and Gene Regulation
- Physical Sciences › Earth and Planetary Sciences › Paleontology › Marine Invertebrate Physiology and Ecology
- Life Sciences › Agricultural and Biological Sciences › Plant Science › Chromosomal and Genetic Variations
- Keywords
- bilaterian origin, bilaterian evolution, transcription factor regulation, developmental gene regulation
- MeSH terms
- Animals, Embryo, Nonmammalian, Biological Evolution, Gene Expression Regulation, Genes, Homeobox, Invertebrates, Phylogeny, Transcription Factors, Body Patterning
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