Cited by 232

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Caspase-6 role in apoptosis of human neurons, amyloidogenesis, and Alzheimer’s disease.

LeBlanc, Andréa, Liu, Hui, Goodyer, Cynthia, Bergeron, Catherine, Hammond, Jennifer·1999·Journal of Biological Chemistry

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Crossref · 10.1074/jbc.274.33.23426

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  • Caspase-3, -6 and -8 cleave APP mainly between amino acids V664-D665 (APP695 numbering) within the intracytoplasmic domain.

    “Several studies have demonstrated in a variety of culture cell systems the ability of caspase-3, -6 and -8 to cleave APP, mainly between amino acids V664-D665 (APP695 numbering) within the intracytoplasmic domain (Gervais et al., 1999; LeBlanc et al., 1999; Pellegrini et al., 1999; Weidemann et al., 1999).”

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Metadata

Authors
LeBlanc, A., Liu, H., Goodyer, C., Bergeron, C., & Hammond, J.
Venue
Journal of Biological Chemistry
Publisher
Elsevier BV
Published
1999-08
Volume
274
Issue
33
Pages
23426-23436
ISSN
0021-9258
Cited by
232
References
9
Language
en

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