Low Density Lipoprotein Receptor-related Protein 1 Promotes Anti-apoptotic Signaling in Neurons by Activating Akt Survival Pathway

Fuentealba, Rodrigo A.; Liu, Qiang; Kanekiyo, Takahisa; Zhang, Juan; Bu, Guojun

doi:10.1074/jbc.m109.021030

Cited by 97

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Low Density Lipoprotein Receptor-related Protein 1 Promotes Anti-apoptotic Signaling in Neurons by Activating Akt Survival Pathway

Fuentealba, Rodrigo A., Liu, Qiang, Kanekiyo, Takahisa, Zhang, Juan, Bu, Guojun·2009·Journal of Biological Chemistry

DOI 10.1074/jbc.m109.021030

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LRP1 plays a critical role in neuronal viability by regulating key survival signalling pathways.
“Increasing evidence also shows that LRP1 functions as a signal-transducing receptor (Herz and Strickland, 2001) and that LRP1 plays a critical role in neuronal viability by regulating key survival signalling pathways (Fuentealba et al., 2009).”
From Heparan Sulphate Proteoglycan and the Low-Density Lipoprotein Receptor-Related Protein 1 Constitute Major Pathways for Neuronal Amyloid-β Uptake (2011) · cites this paper as Fuentealba et al., 2009

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Amyloid beta oligomers induce impairment of neuronal insulin receptors
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Authors: Fuentealba, R. A., Liu, Q., Kanekiyo, T., Zhang, J., & Bu, G.
Venue: Journal of Biological Chemistry
Publisher: Elsevier BV
Published: 2009-12
Volume: 284
Issue: 49
Pages: 34045-34053
ISSN: 0021-9258
DOI: 10.1074/jbc.m109.021030
Cited by: 97
References: 10
Language: en
Licence: www.elsevier.com/tdm/userlicense/1.0/ (tdm)
creativecommons.org/licenses/by/4.0/ (vor, 3924 d)

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Low Density Lipoprotein Receptor-related Protein 1 Promotes Anti-apoptotic Signaling in Neurons by Activating Akt Survival Pathway

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