The Disabled 1 Phosphotyrosine-Binding Domain Binds to the Internalization Signals of Transmembrane Glycoproteins and to Phospholipids

Howell, Brian W.; Lanier, Lorene M.; Frank, Ronald; Gertler, Frank B.; Cooper, Jonathan A.

doi:10.1128/mcb.19.7.5179

Cited by 317

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The Disabled 1 Phosphotyrosine-Binding Domain Binds to the Internalization Signals of Transmembrane Glycoproteins and to Phospholipids

Howell, Brian W., Lanier, Lorene M., Frank, Ronald, Gertler, Frank B., Cooper, Jonathan A.·1999·Molecular and Cellular Biology

DOI 10.1128/mcb.19.7.5179

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Some PTB domains, including the domain in ARH, bind phosphoinositides.
“some PTB domains, including the domain in ARH, bind phosphoinositides (8,11,12).”
From The Modular Adaptor Protein ARH Is Required for Low Density Lipoprotein (LDL) Binding and Internalization but Not for LDL Receptor Clustering in Coated Pits (2004) · cites this paper as [11]
The Discussion (page unavailable) reports that the Dab1 PTB domain binds phosphoinositides and describes phosphoinositide binding by the Shc PTB domain. This supports the general statement about some PTB domains, but our copy does not identify ARH or establish that its domain binds phosphoinositides. (LLM, conf=0.88)
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Authors: Howell, B. W., Lanier, L. M., Frank, R., Gertler, F. B., & Cooper, J. A.
Affiliations: Fred Hutchinson Cancer Research Center
Massachusetts Institute of Technology
AG Molecular Recognition, GBF
Venue: Molecular and Cellular Biology
Publisher: Informa UK Limited
Published: 1999-07
Volume: 19
Issue: 7
Pages: 5179-5188
ISSN: 1098-5549
DOI: 10.1128/mcb.19.7.5179
Cited by: 317
References: 4
Language: en
Licence: journals.asm.org/non-commercial-tdm-license (tdm)

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The Disabled 1 Phosphotyrosine-Binding Domain Binds to the Internalization Signals of Transmembrane Glycoproteins and to Phospholipids

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