Cited by 409Algal biology and biofuel productionSeaweed-derived Bioactive CompoundsFood Industry and Aquatic Biology

The DOI matches its Crossref record; 89 of the 96 references it cites were found in a registry or an index.

Microalgae as food and supplement

Kay, Robert A., Barton, Larry L.·1991·Critical Reviews in Food Science and Nutrition

Open this paper in CoChat — free account

Abstract

The microalgae Chlorella spp., Dunaliella spp., and Scenedesmus spp., and the cyanobacteria Spirulina spp., and Aphanizomenon flos-aquae, are being used as nutrient-dense foods and sources of fine chemicals. They have significant amounts of lipid, protein, chlorophyll, carotenoids, vitamins, minerals, and unique pigments. They may also have potent probiotic compounds that enhance health. Their historical and current use are reviewed in this article.

Integrity signals

Registry

Crossref · 10.1080/10408399109527556

Cites

89 of 89 references verified0 citation errors · 0 not checkable

Statistics

Recomputing p-values needs the paper’s full text.

Claims the paper makes

This paper’s full text isn’t openly available, so its claims and self-check weren’t run. The registry and citation checks still apply.

Claims other papers make about this one

Each is checked against this paper’s own text: does it say what the citing paper says it does?

Biology of microorganisms
Brock, T. D. (1970) · Cited by 1,903
Micro‐algal biotechnology
Rogers, L. J. (1988) · FEBS Letters · doi:10.1016/0014-5793(88)80268-0 · Cited by 1,289
Spirulina, the edible microorganism.
Ciferri, O. (1983) · Microbiological Reviews · doi:10.1128/mmbr.47.4.551-578.1983 · Cited by 745
Microalgal Biotechnology
Borowitzka, M. A., & Borowitzka, L. J. (2021) · Royal Society of Chemistry eBooks · doi:10.1039/9781839162473 · Cited by 568
CRC Handbook of microalgal mass culture
RICHMOND, A. E. (2017) · Medical Entomology and Zoology · Cited by 482
Algal Culture from Laboratory to Pilot Plant
(1953) · AIBS Bulletin · doi:10.1093/aibsbulletin/3.5.11 · Cited by 457
Handbook of Microalgal Mass Culture (1986)
(2017) · CRC Press eBooks · doi:10.1201/9780203712405 · Cited by 420
Progress in Phycological Research
MOSS, B. L. (1985) · Phycologia · doi:10.2216/i0031-8884-24-3-374a.1 · Cited by 397
Algae biomass: production and use
Shelef, G., Soeder, C. J., Balaban, M., ule-fituaḥ, M. H.-L. L.-M., & Umweltforschung, G. F. S. U. (1980) · Cited by 304
AIDS-Antiviral Sulfolipids From Cyanobacteria (Blue-Green Algae)
Gustafson, K. R., Cardellina, J. H., Fuller, R. W., Weislow, O. S., Kiser, R. F., Snader, K. M., Patterson, G. M. L., & Boyd, M. R. (1989) · JNCI Journal of the National Cancer Institute · doi:10.1093/jnci/81.16.1254 · Cited by 302

Show all 96 references

Research works printed but not linked: 95

Stadler T., 1988, Algal Biotechnology
Morimura Y., 1954, Food Technol., 8, 179
Albitskaya O. N., 1979, Appl. Biochem. Microbiol., 15, 568
Chiba Shoyu, 1980, J. Jpn. Soy Sauce Res. Inst., 6, 92
Becker E. W., 1981, Process Biochem., 16, 10
Becker E. W., 1986, Handbook of Microalgal Mass Culture, 339
Borowitzka M. A., 1988, Micro‐algal Biotechnology, 153
Borowitzka M. A., 1988, Micro‐algal Biotechnology, 257
Voronskova S. S., 1980, Spirulina platensis, Appl. Biochem. Microbiol., 16, 266
Cohen Z., 1986, Handbook of Microalgal Mass Culture, 421
Juettner F., 1982, Process Biochem., 17, 2
Finney K. F., 1984, Cereal Chem., 61, 402
Borowitzka, M. A. and Borowitzka, L. J. 1988. Dunaliella in Micro‐algal Biotechnology , Edited by: Borowitzka, M. A. and Borowitzka, L. J. 27New York: Cambridge University Press.
Finney K. F., 1984, Cereal Chem., 61, 402
10.1002/bit.260230608 · DOI
Richmond, A. 1988. Spirulina in Micro‐algal Biotechnology , Edited by: Borowitzka, M. A. and Borowitzka, L. J. 85New York: Cambridge University Press.
Vanossi L., 1982, Industrie Alimentari, 21, 118
Guerin‐Dumartrait E., 1975, Annales Nutr. l'Aliment., 29, 489
Hills, C. and Nakamura, H. 1978. Food from Sunlight , 329Boulder Creek, CA: University of the Trees Press.
Soong P., 1980, Algae Biomass, 97
Gudin C., 1988, Algal Biotechnology, 33
Payer H. D., 1980, Ergebnisse Limnologie, 11, 41
Richmond A., 1978, Ergebnisse Limnologie, 11, 274
Oh‐Hama, T. and Miyachi, S. 1988. Chlorella, in Micro‐Algal Biotechnology , Edited by: Borowitzka, M. A. and Borowitzka, L. J. 3New York: Cambridge University Press.
Soeder, C. J. and Hegewald, E. 1988. Scenedesmus in Micro‐Algal Biotechnology , Edited by: Borowitzka, M. A. and Borowitzka, L. J. 59New York: Cambridge University Press.
Henrikson R., 1989, Earth Food Spirulina
Bewicke D., 1984, Chlorella the Emerald Food
Oswald W. J., 1968, Single‐Cell Protein, 294
Fox R. D., 1983, Algoculture
Richmond A., 1983, Biotechnology, 109
Becker E. W., 1988, Microl‐algal Biotechnology, 222
Bayanova Yu. I., 1981, Appl. Biochem. Microbiol., 17, 292
Rodriquez L. M., 1981, Grasas y Aceites, 32, 245
Aaronson S., 1980, Algae Biomass, 575
Godinez J. L., 1984, Nutr. Rep. Intl., 30, 1279
Nagasawa H., 1989, Anticancer Res., 9, 71
Devi M. A., 1983, Nutr. Rep. Int., 28, 519
Anon, 1988, Earthrise Newsletter, #10
Nakaya N., 1988, Spirulina, Nutr. Rep. Int., 37, 1329
Sano T., 1987, Artery, 14, 76
Fica V., 1984, Rev. Med. Int. Med. Int., 36, 225
Rotkovska D., 1989, Strahlenther. Onkol., 165, 813
Vacek A., 1990, Exp. Heamatol., 18, 237
Anon, 1990, Earthrise Newsletter, #13
Anon, 1990, Earthrise Newsletter, #14
Craig R., 1988, Micro‐algal Biotechnology, 415
Van Der Meer J., 1988, Algae and Human Affairs, 511
Johnson P., 1986, Nutr. Reports Int., 34, 1063
Shoptaugh N. A. H., 1979, Dissertation Abstr. Int.> B, 39, 5363
Trainor, F. R. 1978. Introductory Phycology , 85New York: John Wiley & Sons.
Hills, C. and Nakamura, H. 1978. Food From Sunlight , 36Boulder Creek, CA: University of the Trees Press.
Spencer K. G., 1988, Algae and Human Affairs, 237
Richmond A., 1986, Handbook of Microalgal Mass Culture, 69
Lee H. T., 1977, Chlorella, J. Formosan Med. As‐soc., 76, 272
Lin Y. C., 1969, J. Formosan Med. Assoc., 68, 15
Ishibashi M., 1971, Bull. Azabu. Vet. Coll., 22, 125
1972, Biol. Abstr., 54, 9694
Okuda M., 1975, Jpn. J. Nutr., 33, 3, 10.5264/eiyogakuzashi.33.3 · DOI
Wang L. F., 1979, J. Formosan Med. Assoc., 78, 1010
Wang L. F., 1980, J. Formosan Med. Assoc., 79, 1
Hills, C. and Nakamura, H. 1978. Food From Sunlight , 41Boulder Creek, CA: University of the Trees Press.
Soeder C. J., 1986, Handbook of Microalgal Mass Culture, 25
Soeder, C. J. and Hegewald, E. 1988. Scenedesmus in Micro‐Algal Biotechnology , Edited by: Borowitzka, M. A. and Borowitzka, L. J. 59Cambridge: Cambridge University Press.
Prasomzup U., 1979, Food, 1, 294
Kofranyl E., 1978, Ergebnisse der Lim‐nologie, 11, 150
Becker E. W., 1978, Ergebnisse der Lim‐nologie, 11, 71
Hernandez V., 1978, Scenedesmus acutus, Ergebnisse der Limnologie, 11, 211
Heussler P., 1978, Ergebnisse der Limnologie, 11, 17
Arafah A., 1980, Cereal Chem., 57, 35
Venkataraman L. V., 1977, Nut. Rep. Int., 16, 231
Gross U., 1978, Scenedesmus, Ergebnisse der Limnologie, 11, 174
Trainor, F. R. 1978. Introductory Phycology , 32New York: John Wiley & Sons.
Delpeuch F., 1975, Annales Nutr. l'Aliment., 29, 497
Anderson D. W., 1987, Poultry Sci., 66
Saxena P. N., 1982, Avian Res., 66, 41
Blum J. C., 1976, Ann. Nutr. Aliment., 29, 651
Blum J. C., 1976, Ann. Nutr. Aliment., 30, 675
Williams H. I., 1985, Res. Exten. Ser., 056, 3
Fevrier C., 1976, Ann. Nutr. Aliment., 29, 625
Yap T. N., 1982, Nutr. Rep. Int., 25, 543
Maranesi M., 1985, Spirulina maxima, Acta Vitaminol. Enzymol., 6, 295
Yannai S., 1979, Nutr. Rep. Int., 19, 391
Al'Bitskaya O. N., 1979, Appl. Biochem. Microbiol., 15, 468
Lin L. P., 1985, Food Microstructure, 4, 341
Vincenzini M., 1983, Progr. Food Eng., 11, 563
Vermorel M., 1975, Ann. Nutr. l'Aliment., 29, 535
Tamura Y., 1979, J. Food Hygienic Soc. Jpn., 20, 173, 10.3358/shokueishi.20.173 · DOI
Materassi R., 1980, Algae Biomass, 619
Shifrin N. S., 1980, Algae Biomass Production and Use, 627
Kenyon C. N., 1972, Arch. Microbiol., 83, 216
Saxena P. N., 1982, Spirulina platensis, Experientia, 38, 14
Boudene C., 1975, Ann. Nutr. l'Aliment., 29, 577
Orimo H., 1984, Jpn. J. Nutr., 42, 43, 10.5264/eiyogakuzashi.42.43 · DOI
Piret T., 1975, Gambloux, 85, 83
Devi M. A., 1979, Nutr. Rep. Int., 19, 785

Sorted by citations

Items 101–200 of 409

Polar lipidomic profile shows Chlorococcum amblystomatis as a promising source of value-added lipids
Conde, T. A., Couto, D., Melo, T., Costa, M., Silva, J., Domingues, M. R., & Domingues, P. (2021) · Scientific Reports · doi:10.1038/s41598-021-83455-y · Cited by 58
Effects of Dietary Fermented Chlorella vulgaris (CBT®) on Growth Performance, Relative Organ Weights, Cecal Microflora, Tibia Bone Characteristics, and Meat Qualities in Pekin Ducks
Oh, S., Zheng, L., Kwon, H. J., Choo, Y. K., Lee, K.-W., Kang, C. W., & An, B. (2014) · Asian-Australasian Journal of Animal Sciences · doi:10.5713/ajas.14.0473 · Cited by 57
Enhancement of Natural Killer Cell Activity in Healthy Subjects by Immulina®, a Spirulina Extract Enriched for Braun-Type Lipoproteins
Nielsen, C., Balachandran, P., Christensen, O., Pugh, N., Tamta, H., Sufka, K., Wu, X., Walsted, A., Schjørring-Thyssen, M., Enevold, C., et al. (2010) · Planta Medica · doi:10.1055/s-0030-1250043 · Cited by 56
Microalgal food supplements from the perspective of Polish consumers: patterns of use, adverse events, and beneficial effects
Rzymski, P., & Jaśkiewicz, M. (2017) · Journal of Applied Phycology · doi:10.1007/s10811-017-1079-5 · Cited by 55
Studies on thermal decomposition behaviors of demineralized low-lipid microalgae by TG-FTIR
Wang, J. J., Ma, X., Yu, Z., Peng, X., & Lin, Y. (2018) · Thermochimica Acta · doi:10.1016/j.tca.2018.01.001 · Cited by 56
Microalgal Lipid Extracts Have Potential to Modulate the Inflammatory Response: A Critical Review
Conde, T., Zabetakis, I., Τσούπρας, Α., Medina, I., Costa, M., Silva, J., Neves, B. M., Domingues, P. M., & Domingues, M. R. (2021) · International Journal of Molecular Sciences · doi:10.3390/ijms22189825 · Cited by 57
Transformation of Cyanobacteria
Vioque, A. (2008) · Advances in experimental medicine and biology · doi:10.1007/978-0-387-75532-8_2 · Cited by 54
Selenium from Selenium-Rich Spirulina Is Less Bioavailable than Selenium from Sodium Selenite and Selenomethionine in Selenium-Deficient Rats
Cases, J., Napolitano, A., Caporiccio, B., Besançon, P., Rouanet, J.-M., Vacchina, V., & Lobinski, R. (2001) · The Journal of Nutrition · doi:10.1093/jn/131.9.2343 · Cited by 53
Microalgae a Superior Source of Folates: Quantification of Folates in Halophile Microalgae by Stable Isotope Dilution Assay
Woortman, D. V., Fuchs, T., Striegel, L., Fuchs, M., Weber, N., Brück, T., & Rychlik, M. (2020) · Frontiers in Bioengineering and Biotechnology · doi:10.3389/fbioe.2019.00481 · Cited by 55
Chlorella modulates insulin signaling pathway and prevents high-fat diet-induced insulin resistance in mice
Vecina, J. F., Oliveira, A. G., Araújo, T. G., Baggio, S. R., Torello, C. O., Saad, M. J. A., & Queiroz, M. L. S. (2013) · Life Sciences · doi:10.1016/j.lfs.2013.11.020 · Cited by 53
Safety evaluation of Whole Algalin Protein (WAP) from Chlorella protothecoides
Szabo, N. J., Matulka, R. A., & Chan, T. (2013) · Food and Chemical Toxicology · doi:10.1016/j.fct.2013.05.035 · Cited by 52
In vivo immunomodulatory activity of polysaccharides derived from Chlorella pyrenoidosa
Yang, F., Shi, Y., Sheng, J., & Hu, Q. (2006) · European Food Research and Technology · doi:10.1007/s00217-006-0315-z · Cited by 52
Spirulina platensis versus silymarin in the treatment of chronic hepatitis C virus infection. A pilot randomized, comparative clinical trial
Yakoot, M., & Salem, A. (2012) · BMC Gastroenterology · doi:10.1186/1471-230x-12-32 · Cited by 52
Scale-up cultivation of Chlorella ellipsoidea from indoor to outdoor in bubble column bioreactors
Wang, S.-K., Hu, Y.-R., Wang, F., Stiles, A. R., & Liu, C.-Z. (2014) · Bioresource Technology · doi:10.1016/j.biortech.2014.01.023 · Cited by 58
Mechanisms involved in the antiplatelet effect of C-phycocyanin
Chiu, H., Yang, S., Kuo, Y.-L., Lai, Y.-S., & Chou, T. (2006) · British Journal Of Nutrition · doi:10.1079/bjn20051643 · Cited by 50
Chlorella vulgaris, a novel microalgal source for l-asparaginase production
Ebrahiminezhad, A., Rasoul‐Amini, S., Ghoshoon, M. B., & Ghasemi, Y. (2014) · Biocatalysis and Agricultural Biotechnology · doi:10.1016/j.bcab.2013.10.005 · Cited by 50
Safety and immunoenhancing effect of a Chlorella-derived dietary supplement in healthy adults undergoing influenza vaccination: randomized, double-blind, placebo-controlled trial.
Halperin, S. A., Smith, B. R., Nolan, C., Shay, J., & Kralovec, J. A. (2003) · Europe PMC (PubMed Central) · Cited by 50
Hepatoprotective and hypolipidemic effects of Spirulina platensis in rats administered mercuric chloride
Bash, B. (2011) · African Journal of Pharmacy and Pharmacology · doi:10.5897/ajmr10.330 · Cited by 50
Spirulina maxima Extract Prevents Neurotoxicity via Promoting Activation of BDNF/CREB Signaling Pathways in Neuronal Cells and Mice
Koh, E.-J., Seo, Y.-J., Choi, J., Lee, H. Y., Kang, D.-H., Kim, K.-J., & Lee, B.-Y. (2017) · Molecules · doi:10.3390/molecules22081363 · Cited by 49
Transformation of Spirulina platensis Strain C1 (Arthrospira sp. PCC9438) with Tn5 Transposase?Transposon DNA?Cation Liposome Complex
Kawata, Y., Yano, S., Kojima, H., & Toyomizu, M. (2004) · Marine Biotechnology · doi:10.1007/s10126-003-0037-1 · Cited by 48
The effects of nitrogen and phosphorus deficiencies and nitrite addition on the lipid content of Chlorella vulgaris (Chlorophyceae)
Mutlu, Y., Uslu, L., Ko, K., & Durmaz, Y. (2011) · AFRICAN JOURNAL OF BIOTECHNOLOGY · Cited by 49
Effect of dietary replacement of fishmeal with Chlorella vulgaris on growth performance, energy utilization and digestive enzymes in Macrobrachium rosenbergii postlarvae
Radhakrishnan, S., Bhavan, P. S., Seenivasan, C., & Muralisankar, T. (2015) · Advances in Aquaculture and Fisheries Management · doi:10.5897/ijfa15.0471 · Cited by 52
A complex Enrichment Diet improves growth and health in the endangered Wyoming toad (Bufo baxteri)
Li, H., Vaughan, M. J., & Browne, R. K. (2009) · Zoo Biology · doi:10.1002/zoo.20223 · Cited by 48
Characterization and pyrolysis of Chlorella vulgaris and Arthrospira platensis: potential of bio-oil and chemical production by Py-GC/MS analysis
Almeida, H. N., Calixto, G. Q., Chagas, B. M. E., Melo, D. M. D. A., Resende, F. D. M., Melo, M. A. F., & Braga, R. M. (2017) · Environmental Science and Pollution Research · doi:10.1007/s11356-017-9009-2 · Cited by 48
Effective transformation of the cyanobacterium Spirulina platensis using electroporation
Toyomizu, M., Suzuki, K., Kawata, Y., Kojima, H., & Akiba, Y. (2001) · Journal of Applied Phycology · doi:10.1023/a:1011182613761 · Cited by 47
C-phycocyanin attenuates RANKL-induced osteoclastogenesis and bone resorption in vitro through inhibiting ROS levels, NFATc1 and NF-κB activation
AlQranei, M. S., Aljohani, H., Majumdar, S., Senbanjo, L. T., & Chellaiah, M. A. (2020) · Scientific Reports · doi:10.1038/s41598-020-59363-y · Cited by 48
Safety evaluation of a high-lipid algal biomass from Chlorella protothecoides
Day, A. G., Brinkmann, D., Franklin, S. E., Espina, K., Rudenko, G. N., Roberts, A. S., & Howse, K. S. (2009) · Regulatory Toxicology and Pharmacology · doi:10.1016/j.yrtph.2009.06.014 · Cited by 47
Changes of the Total Lipid and Omega-3 Fatty Acid Contents in two Microalgae Dunaliella Salina and Chlorella Vulgaris Under Salt Stress
Rismani, S., & Shariati, M. (2017) · Brazilian Archives of Biology and Technology · doi:10.1590/1678-4324-2017160555 · Cited by 48
Purification of c-phycocyanin from Spirulina fusiformis and its effect on the induction of urokinase-type plasminogen activator from calf pulmonary endothelial cells
Madhyastha, H., Radha, K. S., Sugiki, M., Omura, S., & Maruyama, M. (2005) · Phytomedicine · doi:10.1016/j.phymed.2005.09.006 · Cited by 46
Microalgae as a safe food source for animals: nutritional characteristics of the acidophilic microalga Coccomyxa onubensis
Navarro, F., Forján, E., Vázquez, M., Montero, Z., Bermejo, E., Castaño, M. Á., Toimil, A., Chagüaceda, E., García-Sevillano, M. Á., Sánchez, M., et al. (2016) · Food & Nutrition Research · doi:10.3402/fnr.v60.30472 · Cited by 47
Selenium-Enriched Spirulina (SeE-SP) Enhance Antioxidant Response, Immunity, and Disease Resistance in Juvenile Asian Seabass, Lates calcarifer
Siddik, M. A. B., Vatsos, I. N., Rahman, M. A., & Pham, H. D. (2022) · Antioxidants · doi:10.3390/antiox11081572 · Cited by 44
Exercise and spirulina control non-alcoholic hepatic steatosis and lipid profile in diabetic Wistar rats
de Moura, L. P., Puga, G. M., Beck, W. R., Teixeira, I. P., Ghezzi, A. C., Silva, G. A., & de Mello, M. A. R. (2011) · Lipids in Health and Disease · doi:10.1186/1476-511x-10-77 · Cited by 45
Spirulina maxima extract prevents cell death through BDNF activation against amyloid beta 1-42 (Aβ 1-42 ) induced neurotoxicity in PC12 cells
Koh, E.-J., Kim, K.-J., Choi, J., Kang, D.-H., & Lee, B.-Y. (2018) · Neuroscience Letters · doi:10.1016/j.neulet.2018.02.057 · Cited by 43
Aquaculture: An overview of chemical ecology of seaweeds (food species) in natural products
Gnanavel, V., Roopan, S. M., & Rajeshkumar, S. (2019) · Aquaculture · doi:10.1016/j.aquaculture.2019.04.004 · Cited by 43
Purification of an iron-chelating peptide from spirulina protein hydrolysates
Kim, N., Jung, S.-H., Kim, J., Kim, S.-H., Ahn, H.-J., & Song, K. B. (2014) · Journal of the Korean Society for Applied Biological Chemistry · doi:10.1007/s13765-013-4211-5 · Cited by 42
Dietary silicon-enriched spirulina improves early atherosclerosis markers in hamsters on a high-fat diet
Vidé, J., Virsolvy, A., Romain, C., Ramos, J., Jouy, N., Richard, S., Cristol, J., Gaillet, S., & Rouanet, J. (2015) · Nutrition · doi:10.1016/j.nut.2015.03.014 · Cited by 41
Plant insulin or glucokinin: a conflicting issue
Xavier‐Filho, J., Oliveira, A. E. A., da Silva, L. B., Azevedo, C. R., Venâncio, T. M., Machado, O. L. T., Oliva, M. L. V., Fernandes, K. V. S., & Xavier‐Neto, J. (2003) · Brazilian Journal of Plant Physiology · doi:10.1590/s1677-04202003000200002 · Cited by 41
Effects of dietary supplementation with a chlorella by‐product on the growth performance, immune response, intestinal microflora and intestinal mucosal morphology in broiler chickens
Kang, H.-K., Park, S. B., & Kim, C. H. (2016) · Journal of Animal Physiology and Animal Nutrition · doi:10.1111/jpn.12566 · Cited by 44
Clinical Effects of Subgingivally Delivered Spirulina Gel in Chronic Periodontitis Cases: A Placebo Controlled Clinical Trial
Mahendra, J. (2013) · JOURNAL OF CLINICAL AND DIAGNOSTIC RESEARCH · doi:10.7860/jcdr/2013/5793.3517 · Cited by 40
The effect of processing of Chlorella vulgaris: K-5 on in vitro and in vivo digestibility in rats
KOMAKI, H., Yamashita, M., Yoshitsugu, N. I. W. A., Tanaka, Y., Kamiya, N., Ando, Y., & Furuse, M. (1998) · Animal Feed Science and Technology · doi:10.1016/s0377-8401(97)00089-8 · Cited by 40
An overview on marine anti-allergic active substances for alleviating food-induced allergy
Wang, K., Pramod, S. N., Pavase, T. R., Ahmed, I., Lin, H., Liu, L., Tian, S., Lin, H., & Li, Z. (2019) · Critical Reviews in Food Science and Nutrition · doi:10.1080/10408398.2019.1650716 · Cited by 39
Spirulina platensis Extract Enhances Chicken Macrophage Functions After in vitro Exposure
Qureshi, M. A., Kidd, M. T., & Ali, R. A. (2008) · Journal of Nutritional Immunology · doi:10.1300/j053v03n04_04 · Cited by 39
Assessment of Selenium Bioavailability from High-Selenium Spirulina Subfractions in Selenium-Deficient Rats
Cases, J., Wysocka, I. A., Caporiccio, B., Jouy, N., Besançon, P., Szpunar, J., & Rouanet, J. (2002) · Journal of Agricultural and Food Chemistry · doi:10.1021/jf011646t · Cited by 38
‘Complementary ENT’: a systematic review of commonly used supplements
Karkos, P. D., Leong, S. C., Arya, A. K., Papouliakos, S. M., Apostolidou, M., & Issing, W. J. (2006) · The Journal of Laryngology & Otology · doi:10.1017/s002221510600449x · Cited by 39
Dietary Feeding Lycopene, Citric Acid, and Chlorella Alleviated the Neurotoxicity of Polyethylene Microplastics in African Catfish (Clarias gariepinus)
Hamed, M., Soliman, H. A. M., Eid, Z., Naggar, Y. A., & Sayed, A. E. H. (2022) · Frontiers in Environmental Science · doi:10.3389/fenvs.2022.869727 · Cited by 38
Development and Validation of a Liquid Chromatography-Tandem Mass Spectrometry Method for the Quantitation of Microcystins in Blue-Green Algal Dietary Supplements
Parker, C. H., Stutts, W. L., & DeGrasse, S. L. (2015) · Journal of Agricultural and Food Chemistry · doi:10.1021/acs.jafc.5b04292 · Cited by 42
Potential use of the astaxanthin-producing microalga, Monoraphidium sp. GK12, as a functional aquafeed for prawns
Fujii, K., Nakashima, H., Hashidzume, Y., Uchiyama, T., Mishiro, K., & Kadota, Y. (2009) · Journal of Applied Phycology · doi:10.1007/s10811-009-9468-z · Cited by 37
Enhancement of proliferation and differentiation in bone marrow hematopoietic cells by Spirulina (Arthrospira) platensis in mice
Hayashi, O., Ono, S., Ishii, K., Shi, Y. H., Hirahashi, T., & KATOH, T. (2006) · Journal of Applied Phycology · doi:10.1007/s10811-005-9014-6 · Cited by 38
An aqueous Chlorella extract inhibits IL-5 production by mast cells in vitro and reduces ovalbumin-induced eosinophil infiltration in the airway in mice in vivo
Kralovec, J. A., Coombs, M. R. P., Liu, F., Maydanski, E., Ewart, H. S., Watson, L. V., Barrow, C. J., & Lin, T. (2004) · International Immunopharmacology · doi:10.1016/j.intimp.2004.11.016 · Cited by 36
Process-intensified extraction of phycocyanin followed by β-carotene from Spirulina platensis using ultrasound-assisted extraction
Bachchhav, M. B., Kulkarni, M. V., & Ingale, A. G. (2019) · Separation Science and Technology · doi:10.1080/01496395.2019.1580293 · Cited by 35
Thermogravimetric characterisation and kinetic analysis of Nannochloropsis sp. and Tetraselmis sp. microalgae for pyrolysis, combustion and oxy-combustion
Dessì, F., Mureddu, M., Ferrara, F., Fermoso, J., Orsini, A., Sanna, A., & Pettinau, A. (2020) · Energy · doi:10.1016/j.energy.2020.119394 · Cited by 35
Sustained Photosynthesis and Oxygen Generation of Microalgae-Embedded Silk Fibroin Hydrogels
Fu, Y., Xie, X., Wang, Y., Liu, J., Zheng, Z., Kaplan, D. L., & Wang, X. (2021) · ACS Biomaterials Science & Engineering · doi:10.1021/acsbiomaterials.1c00168 · Cited by 35
Nitrate and ammonia: two key nitrogen sources for biomass and phycocyanin production by Arthrospira (Spirulina) platensis
Mousavi, M., Mehrzad, J., Najafi, M. F., Zhiani, R., & Shamsian, S. A. A. (2022) · Journal of Applied Phycology · doi:10.1007/s10811-021-02664-0 · Cited by 36
Effect of maternal Chlorella supplementation on carotenoid concentration in breast milk at early lactation
Nagayama, J., Noda, K., Uchikawa, T., Maruyama, I., Shimomura, H., & Miyahara, M. (2014) · International Journal of Food Sciences and Nutrition · doi:10.3109/09637486.2014.898257 · Cited by 35
Salivary Secretory Immunoglobulin a secretion increases after 4-weeks ingestion of chlorella-derived multicomponent supplement in humans: a randomized cross over study
Otsuki, T., Shimizu, K., Iemitsu, M., & Kono, I. (2011) · Nutrition Journal · doi:10.1186/1475-2891-10-91 · Cited by 34
Polysaccharide from Spirulina platensis Evokes Antitumor Activity in Gastric Cancer Cells via Modulation of Galectin-3 and Exhibited Cyto/DNA Protection: Structure–Function Study
Uppin, V., Dharmesh, S. M., & Ravi, S. (2022) · Journal of Agricultural and Food Chemistry · doi:10.1021/acs.jafc.2c00176 · Cited by 34
Antioxidant Efficacy of a Spirulina Liquid Extract on Oxidative Stress Status and Metabolic Disturbances in Subjects with Metabolic Syndrome
Koite, N. L. N., Sanogo, N. I., Lépine, O., Bard, J., & Ouguerram, K. (2022) · Marine Drugs · doi:10.3390/md20070441 · Cited by 33
The Potential of Microalgae Lipids for Edible Oil Production
Huang, Y., Zhang, D., Xue, S., Wang, M., & Cong, W. (2016) · Applied Biochemistry and Biotechnology · doi:10.1007/s12010-016-2108-6 · Cited by 32
EFFECTS OF DIETARY Spirulina maxima ON ENDOTHELIUM DEPENDENT VASOMOTOR RESPONSES OF RAT AORTIC RINGS
Paredes-Carbajal, M. C., Torres-Durán, P. V., Díaz-Zagoya, J. C., Mascher, D., & Juárez-Oropeza, M. A. (1997) · Life Sciences · doi:10.1016/s0024-3205(97)00715-7 · Cited by 32
The leaves of green plants as well as a cyanobacterium, a red alga, and fungi contain insulin-like antigens
Silva, L. B., Santos, S. S. S., Azevedo, C. R., Cruz, M. A. L., Venâncio, T. M., Cavalcante, C., Uchôa, A. F., Filho, S. A., Oliveira, A. E. A., Fernandes, K. V. S., et al. (2002) · Brazilian Journal of Medical and Biological Research · doi:10.1590/s0100-879x2002000300004 · Cited by 32
Effects of nitrogen and phosphorus limitation on lipid accumulation by Chlorella kessleri str. UTEX 263 grown in darkness
Shrestha, N., Dandinpet, K. K., & Schneegurt, M. A. (2020) · Journal of Applied Phycology · doi:10.1007/s10811-020-02144-x · Cited by 31
Spirulina (Arthrospira platensis): Antiallergic Agent or Hidden Allergen? A Literature Review
Gromek, W., Kołdej, N., Kurowski, M. M., & Majsiak, E. (2024) · Foods · doi:10.3390/foods13071052 · Cited by 35
Effect of Fermented Spirulina maxima Extract on Cognitive‐Enhancing Activities in Mice with Scopolamine‐Induced Dementia
Choi, W. Y., Kang, D. H., & Lee, H.-Y. (2018) · Evidence-based Complementary and Alternative Medicine · doi:10.1155/2018/7218504 · Cited by 30
Efficacy and safety of Chlorella supplementation in adults with chronic hepatitis C virus infection
Azócar, J. A. (2013) · World Journal of Gastroenterology · doi:10.3748/wjg.v19.i7.1085 · Cited by 30
Reduced Concentrations of Soluble Adhesion Molecules after Antioxidant Supplementation in Postmenopausal Women with High Cardiovascular Risk Profiles – A Randomized Double-Blind Study
Goudev, A., Kyurkchiev, S., Gergova, V., Karshelova, E., Georgiev, D. B., Atar, D., Kehayov, I. R., & Nachev, C. (2000) · Cardiology · doi:10.1159/000047322 · Cited by 29
Pilot-scale production of antibacterial substances by the marine diatom Phaeodactylum tricornutum Bohlin
Wang, S., Said, I. H., Thorstenson, C. A., Thomsen, C., Ullrich, M. S., Kuhnert, N., & Thomsen, L. (2018) · Algal Research · doi:10.1016/j.algal.2018.03.014 · Cited by 30
Microalgal Rainbow Colours for Nutraceutical and Pharmaceutical Applications
Ghosh, T., Paliwal, C., Maurya, R., & Mishra, S. (2015) · Springer eBooks · doi:10.1007/978-81-322-2286-6_32 · Cited by 28
Preclinical antitoxic properties ofSpirulina(Arthrospira)
Martínez-Galero, E., Pérez-Pastén-Borja, R., Pérez-Juárez, A., Castillo, L., Gutiérrez-Salmeán, G., & Chamorro, G. (2015) · Pharmaceutical Biology · doi:10.3109/13880209.2015.1077464 · Cited by 27
Microalgae in Food-Energy-Water Nexus: A Review on Progress of Forward Osmosis Applications
Wibisono, Y., Nugroho, W. A., Devianto, L. A., Sulianto, A. A., & Bilad, M. R. (2019) · Membranes · doi:10.3390/membranes9120166 · Cited by 31
Integration of Algal Biofuels With Bioremediation Coupled Industrial Commodities Towards Cost-Effectiveness
Nagi, G. K., Minhas, A. K., Gaur, S., Jain, P., & Mandal, S. (2021) · Frontiers in Energy Research · doi:10.3389/fenrg.2021.735141 · Cited by 29
Protective Effect of Arthrospira maxima on Fatty Acid Composition in Fatty Liver
Torres-Durán, P. V., Paredes-Carbajal, M. C., Mascher, D., Zamora‐González, J., Díaz-Zagoya, J. C., & Juárez-Oropeza, M. A. (2006) · Archives of Medical Research · doi:10.1016/j.arcmed.2005.08.005 · Cited by 28
Effect of Air Nanobubble Water on the Growth and Metabolism of Haematococcus lacustris and Botryococcus braunii
Zhu, J., & Wakisaka, M. (2019) · Journal of Nutritional Science and Vitaminology · doi:10.3177/jnsv.65.s212 · Cited by 27
Enhancement of immune activation activities of Spirulina maxima grown in deep-sea water
Choi, W., Kang, D., & Lee, H. (2013) · International Journal of Molecular Sciences · doi:10.3390/ijms140612205 · Cited by 26
HYPOGLYCEMIC AND HYPOLIPIDEMIC EFFECTS OF SPIRULINA PLATENSIS, PHYCOCYANIN, PHYCOCYANOPEPTIDE AND PHYCOCYANOBILIN ON MALE DIABETIC RATS
El-Sayed, E.-S., Hikal, M., Abo El- Khair, B., El-Ghobashy, R., & El-Assar, A. (2018) · Arab Universities Journal of Agricultural Sciences · doi:10.21608/ajs.2018.28365 · Cited by 26
Dietary supplementation effects of Chlorella vulgaris on performances, oxidative stress status and antioxidant enzymes activities of prepubertal New Zealand White rabbits
Sikiru, A. B., Arangasamy, A., Alemede, I. C., Egena, S. S. A., & Bhatta, R. (2019) · Bulletin of the National Research Centre/Bulletin of the National Research Center · doi:10.1186/s42269-019-0213-8 · Cited by 26
Demonstration of the use of Scenedesmus and Carteria biomass to drive bacterial sulfate reduction by Desulfovibrio alcoholovorans isolated from an artificial wetland
Russell, R. A., Holden, P. J., Wilde, K. L., & Neilan, B. A. (2003) · Hydrometallurgy · doi:10.1016/s0304-386x(03)00160-9 · Cited by 26
Effects of Spirulina platensis on performance, digestibility and serum biochemical parameters of Holstein calves
Heidarpour, A., Fourouz, A.-D., Eh-Shahraki, & Eghbalsaied, S. (2011) · African Journal of Agricultural Research · doi:10.5897/ajar11.1076 · Cited by 26
Environmental assessment of microalgae biodiesel production in Colombia: Comparison of three oil extraction systems
Cárdenas, Y. P., Herrera, I., González-Delgado, Á. D., & Kafarov, V. V. (2013) · CT&F - Ciencia Tecnología y Futuro · doi:10.29047/01225383.59 · Cited by 26
The Influence of Chlorella and Its Hot Water Extract Supplementation on Quality of Life in Patients with Breast Cancer
Noguchi, N., Maruyama, I., & Yamada, A. (2014) · Evidence-based Complementary and Alternative Medicine · doi:10.1155/2014/704619 · Cited by 25
Effect of spirulina food supplement on blood morphological parameters, biochemical composition and on the immune function of sportsmen.
Milašius, K., Malickaitė, R., & Dadelienė, R. (2009) · Biology of Sport · doi:10.5604/20831862.890162 · Cited by 21
Cultivation of Haematococcus pluvialis for Astaxanthin Production
Liu, J., van der Meer, J., Zhang, L., & Zhang, Y. (2016) · CRC Press eBooks · doi:10.1201/b19464-13 · Cited by 25
Algae for Africa: Microalgae as a source of food, feed and fuel in Kenya
Moejes, F. W., & Moejes, K. B. (2017) · AFRICAN JOURNAL OF BIOTECHNOLOGY · doi:10.5897/ajb2016.15721 · Cited by 25
Life cycle assessment of microalgal cultivation medium: biomass, glycerol, and beta-carotene production by Dunaliella salina and Dunaliella tertiolecta
Celente, G. D. S., Schneider, R. D. C. D. S., Julich, J., Rizzetti, T. M., Lobo, E. A., & Sui, Y. (2023) · The International Journal of Life Cycle Assessment · doi:10.1007/s11367-023-02209-2 · Cited by 24
A Revisit of Plant Food Waste Along Food Supply Chains: Impacts and Perspectives
Gonçalves, J., Anjos, O., & Guiné, R. P. F. (2025) · Foods · doi:10.3390/foods14081364 · Cited by 34
Treatment potential of a synergistic botanical pesticide combination for rotifer extermination during outdoor mass cultivation of Spirulina platensis
Huang, Y., Liu, J., Wang, H., & Gao, Z. (2014) · Algal Research · doi:10.1016/j.algal.2014.11.003 · Cited by 24
Spirulina enhanced the skeletal muscle protein in growing rats
Voltarelli, F. A., & de Mello, M. A. R. (2008) · European Journal of Nutrition · doi:10.1007/s00394-008-0740-9 · Cited by 24
Impact of Regular Intake of Microalgae on Nutrient Supply and Cardiovascular Risk Factors: Results from the NovAL Intervention Study
Sandgruber, F., Höger, A.-L., Kunze, J., Schenz, B., Griehl, C., Kiehntopf, M., Kipp, K., Kühn, J., Stangl, G. I., Stefan Lorkowski, A., et al. (2023) · Nutrients · doi:10.3390/nu15071645 · Cited by 23
Production of deuterated β-carotene by metabolic labelling of Spirulina platensis
Gireesh, T., Jayadeep, A., Rajasekharan, K. N., Menon, V. P., Vairamany, M., Tang, G., Nair, P. P., & Sudhakaran, P. R. (2001) · Biotechnology Letters · doi:10.1023/a:1010378401621 · Cited by 23
Analysis and Design of Photobioreactors for Microalgae Production I: Method and Parameters for Radiation Field Simulation
Heinrich, J. M., Niizawa, I., Botta, F. A., Trombert, A. R., & Irazoqui, H. A. (2012) · Photochemistry and Photobiology · doi:10.1111/j.1751-1097.2012.01141.x · Cited by 22
Microcystin-LR and its health impacts: Chemistry, transmission routes, mechanisms of toxicity and target organs
Rajpoot, R., Rajput, S., & Koiri, R. K. (2025) · Toxicology Reports · doi:10.1016/j.toxrep.2025.101996 · Cited by 22
Determination of intracellular lipid and main fatty acids of Nannochloropsis oceanica by ATR-FTIR spectroscopy
Zhang, D., Li, Q., Yan, C., & Cong, W. (2021) · Journal of Applied Phycology · doi:10.1007/s10811-021-02607-9 · Cited by 23
Phytochemicals of algae, Arthospira platensis (spirulina) Chlorella vulgaris (chlorella) and Azolla pinnata (azolla)
Thangaraj, M., Bhavan, P. S., Jayakumar, T., Joen-Rong, S., Manubolu, M., & Pathakoti, K. (2022) · GSC Biological and Pharmaceutical Sciences · doi:10.30574/gscbps.2022.19.2.0167 · Cited by 25
Use of Microorganisms as Nutritional and Functional Feedstuffs for Nursery Pigs and Broilers
Cheng, Y.-C., & Kim, S. W. (2022) · Animals · doi:10.3390/ani12223141 · Cited by 25
Glucomannan and glucomannan plus spirulina added to pork significantly block dietary cholesterol effects on lipoproteinemia, arylesterase activity, and CYP7A1 expression in Zucker fa/fa rats
González-Torres, L., Vázquez‐Velasco, M., Olivero-David, R., Bastida, S., Benedı́, J., González, R. R., González‐Muñoz, M. J., & Sánchez-Muniz, F. J. (2015) · Journal of Physiology and Biochemistry · doi:10.1007/s13105-015-0441-9 · Cited by 22
Increased Anti-Inflammatory Effects on LPS-Induced Microglia Cells by Spirulina maxima Extract from Ultrasonic Process
Choi, W. Y., Sim, J.-H., Lee, J.-Y., Kang, D. H., & Lee, H.-Y. (2019) · Applied Sciences · doi:10.3390/app9102144 · Cited by 22
Lipase-catalysed synthesis of modified lipids
Bornscheuer, U. T., Adamczak, M., & SOUMANOU, M. M. (2012) · Elsevier eBooks · doi:10.1533/9780857097965.149 · Cited by 22
Data-Driven pH Model in Raceway Reactors for Freshwater and Wastewater Cultures
Otálora, P., Guzmán, J. L., Berenguel, M., & Acién, F. G. (2023) · Mathematics · doi:10.3390/math11071614 · Cited by 21
A critical review of the microalgae and cyanobacteria-based biofertilizers: An insight into the cost effectiveness of different algae cultivation strategies
Rahman, A., Fares, A., Veettil, A. V., Mohtar, R. H., & Awal, R. (2025) · Environmental Technology & Innovation · doi:10.1016/j.eti.2025.104480 · Cited by 25
Safety evaluation of a high lipid Whole Algalin Flour (WAF) from Chlorella protothecoides
Szabo, N. J., Matulka, R. A., Kiss, L., & Licari, P. (2012) · Regulatory Toxicology and Pharmacology · doi:10.1016/j.yrtph.2012.03.011 · Cited by 21
Arthrospira (Spirulina) platensis Attenuates Dextran Sulfate Sodium-induced Colitis in Mice by Suppressing Key Pro-inflammatory Cytokines
Garcia, F. A. D. O., Sales‐Campos, H., Yuen, V. G., Machado, J. R., Viana, G. S. D. B., Oliveira, C. J. F., & McNeill, J. H. (2020) · Korean Journal of Gastroenterology · doi:10.4166/kjg.2020.76.3.150 · Cited by 20

Authors: Kay, R. A., & Barton, L. L.
Affiliations: University of New Mexico (US)
ORCID: Barton, Larry L.
Venue: Critical Reviews in Food Science and Nutrition
Publisher: Informa UK Limited
Published: 1991-01
Volume: 30
Issue: 6
Pages: 555-573
ISSN: 1040-8398 (ISSN-L)
1549-7852
DOI: 10.1080/10408399109527556
OpenAlex: W2026261205
Semantic Scholar: b58d8771e859f5a47321cb1bbf1ab5e5f8f33061
Cited by: 408
References: 96
Citations by year: 2026: 9 · 2025: 8 · 2024: 11 · 2023: 17 · 2022: 26 · 2021: 18 · 2020: 24 · 2019: 22 · 2018: 24 · 2017: 15 · 2016: 15 · 2015: 19 · 2014: 24 · 2013: 23 · 2012: 16
FWCI: 0.53
Type: journal article
Language: en
Open access: closed
Locations: Critical Reviews in Food Science and Nutrition (publishedVersion)
PubMed (publishedVersion)
Topics: Physical Sciences › Energy › Renewable Energy, Sustainability and the Environment › Algal biology and biofuel production
Life Sciences › Agricultural and Biological Sciences › Aquatic Science › Seaweed-derived Bioactive Compounds
Life Sciences › Agricultural and Biological Sciences › Food Science › Food Industry and Aquatic Biology
Keywords: microalgae, Chlorella, Dunaliella, Scenedesmus, Spirulina, Aphanizomenon flos-aquae, cyanobacteria, functional foods, dietary supplements, lipids, proteins, carotenoids, chlorophyll, vitamins, minerals, pigments, probiotics, health benefits
MeSH terms: Animals, Diet, Food, Food Supply, Humans, Nutritional Physiological Phenomena, Nutritive Value, Eukaryota

About these checks

Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.

Statistics and arithmetic are recomputed, not judged.

Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.

What counts as a claim ›How we measure confidence ›How we check this ›

Are you an author, or do you see a problem with this page? Request a review

Microalgae as food and supplement

Abstract

Overview

Integrity signals

Verification

Claims the paper makes

Claims other papers make about this one

Citations

Cites

Cited by

Related

Metadata

Record

About these checks