The DOI matches its Crossref record; 92 of the 94 references it cites were found in a registry or an index.
Natural polyphenols: An overview
Open accessAbstract
Plant-derived functional foods are gaining considerable attention due to their safety and therapeutic potentials. Research on plant-based functional foods presents several challenges ranges from hypercholesterolemia to cancer prevention. In last decade, special attention has been paid to edible plants and especially their phytochemicals. Today, there is an increasing interest in their bioactivities provided by these phytochemicals. Polyphenols are the most numerous and widely distributed group of bioactive molecules. Polyphenols have two general classes, one is flavonoids and other is phenolic acids. Among these, flavonoids are further divided into flavones, flavononse, flavonols, flavanols, isoflavones, and phenolic acids are generally classified into hydroxybenzoic and hydroxycinnamic acids. Fruit peel is one of the dense sources for flavonoids and their content may vary from species to species and due to exposure of light. Polyphenols have wide range of molecules and different set of biological activities that are mainly attributed to their structure. Investigations have revealed that polyphenols play a key role to prevent various diseases, like hypercholesterolemia, hyperglycemia, hyperlipidemia, and cancer insurgence. The current review article summarizes the literature pertaining to polyphenols and its allied health benefits.
Overview
Integrity signals
Registry
Cites
Statistics
Verification
Claims the paper makes
Claims other papers make about this one
Each is checked against this paper’s own text: does it say what the citing paper says it does?
In the citing paper
“The presence of these polyphenolic compounds associates with various physiological effects, including anti-inflammatory, antibacterial, antiradical, chemoprotective, and anti-hepatosteatotic properties [77].”
From Nutritional composition and bioactive properties of tropical coconut palm fruit with functional food applications (2025) · cites this paper as [77]
In the citing paper
“Scientists identified a diverse array of phenolic constituents in coconuts, encompassing gallic acid, m-coumaric acid, salicylic acid, catechin acid, and p-coumaric acid.”
From Nutritional composition and bioactive properties of tropical coconut palm fruit with functional food applications (2025) · cites this paper as [77]
Citations
Cites
Hanahan, D., & Weinberg, R. A. (2000) · Cell · doi:10.1016/s0092-8674(00)81683-9 · Cited by 29,219
Polyphenols: Food sources and bioavailability
Manach, C., Scalbert, A., Morand, C., Rémésy, C., & Jiménez, L. (2004) · The American Journal of Clinical Nutrition · doi:10.1093/ajcn/79.5.727 · Cited by 8,175
NF-κB: linking inflammation and immunity to cancer development and progression
Karin, M., & Greten, F. R. (2005) · Nature reviews. Immunology · doi:10.1038/nri1703 · Cited by 3,175
MAP kinase signalling pathways in cancer
Dhillon, A. S., Hagan, S., Rath, O., & Kolch, W. (2007) · Oncogene · doi:10.1038/sj.onc.1210421 · Cited by 2,995
NF-κB in cancer: from innocent bystander to major culprit
Karin, M., Cao, Y., Greten, F. R., & Li, Z. (2002) · Nature reviews. Cancer · doi:10.1038/nrc780 · Cited by 2,476
Polyphenols and disease risk in epidemiologic studies
Arts, I. C., & Hollman, P. C. (2005) · The American Journal of Clinical Nutrition · doi:10.1093/ajcn/81.1.317s · Cited by 1,916 · cited 1×
“An inverse correlation had been found in coronary disease and consumption of flavanols, flavonols, and flavones.([24]) Deaths rate related to cardiovascular disease were reduced with ingestion of flavanones and anthocyanins.”
BackgroundPolyphenols: Antioxidants and beyond
Scalbert, A., Johnson, I. T., & Saltmarsh, M. (2005) · The American Journal of Clinical Nutrition · doi:10.1093/ajcn/81.1.215s · Cited by 1,836
Molecular targets of dietary agents for prevention and therapy of cancer
Aggarwal, B. B., & Shishodia, S. (2006) · Biochemical Pharmacology · doi:10.1016/j.bcp.2006.02.009 · Cited by 1,774
Nrf2–Keap1 defines a physiologically important stress response mechanism
Motohashi, H., & Yamamoto, M. (2004) · Trends in Molecular Medicine · doi:10.1016/j.molmed.2004.09.003 · Cited by 1,725 · cited 1×
“many studies have shown that different fruits and vegetables rich in polyphenols and bioactive compounds are particularly effective in protecting against the development of colon cancer.([59])”
BackgroundThe IKK NF-κB system: a treasure trove for drug development
Karin, M., Yamamoto, Y., & Wang, Q. M. (2004) · Nature Reviews Drug Discovery · doi:10.1038/nrd1279 · Cited by 1,364
Research works printed but not linked: 8
- Archivio D., 2007, Annali-Istituto Superiore di Sanita, 43, 348
- Srini Srinivasan V., Pharmaceutical Dissolution Testing; Informa Healthcare: Cambridge, UK, 2005, 407
- Organization W.H., Global Health Risks: Mortality and Burden of Disease Attributable to Selected Major Risks
- Soliman M.M., 2014, BMC Complementary and Alternative Medicine
- Khan S.G., 1992, Cancer Research, 52, 4050
- Martínez M.E., Tumor Prevention and Genetics III; Springer Science/Business Media, Springer-Verlag: New York, USA, 2005, 177
- Santaguida P.L., 2008, Evidence Report/Technology Assessment, 12, 1
- Stull A.J., 1764, Journal of Nutrition, 2010
Cited by
Sorted by citations
Antioxidants of Natural Plant Origins: From Sources to Food Industry Applications
Lourenço, S. C., Moldão‐Martins, M., & Alves, V. D. (2019) · Molecules · doi:10.3390/molecules24224132 · Cited by 1,191
Antimicrobial Activity of Polyphenols and Alkaloids in Middle Eastern Plants
Othman, L., Sleiman, A., & Abdel‐Massih, R. M. (2019) · Frontiers in Microbiology · doi:10.3389/fmicb.2019.00911 · Cited by 681
Kaczmarek, B. (2020) · Materials · doi:10.3390/ma13143224 · Cited by 633
Pressurized hot water extraction of bioactives
Plaza, M., & Turner, C. (2015) · TrAC Trends in Analytical Chemistry · doi:10.1016/j.trac.2015.02.022 · Cited by 582
Suleria, H. A. R., Barrow, C. J., & Dunshea, F. R. (2020) · Foods · doi:10.3390/foods9091206 · Cited by 377
Self-citation
Metadata
- Authors
- Abbas, M., Saeed, F., Anjum, F. M., Afzaal, M., Tufail, T., Bashir, M. S., Ishtiaq, A., Hussain, S., & Suleria, H. A. R.
- Affiliations
- Government College University, Faisalabad (PK)
- University of the Punjab (PK)
- The University of Queensland (AU)
- Corresponding author
- Saeed, Farhan
- ORCID
- Venue
- International Journal of Food Properties
- Publisher
- Informa UK Limited
- Published
- 2016-12-18
- Volume
- 20
- Issue
- 8
- Pages
- 1689-1699
- ISSN
- 1094-2912 (ISSN-L)
- 1532-2386
- OpenAlex
- W2527889170
- Cited by
- 769
- References
- 94
- Citations by year
- 2026: 63 · 2025: 122 · 2024: 123 · 2023: 121 · 2022: 105 · 2021: 101 · 2020: 75 · 2019: 38 · 2018: 14 · 2017: 6
- FWCI
- 15.25
- Type
- journal article
- Language
- en
- Open access
- bronze
- doi.org
- Locations
- International Journal of Food Properties (publishedVersion)
- Own your potential (DEAKIN) (submittedVersion)
- Figshare (submittedVersion, cc-by)
- Topics
- Health Sciences › Medicine › Biochemistry (medical) › Phytochemicals and Antioxidant Activities
- Health Sciences › Medicine › Endocrinology, Diabetes and Metabolism › Natural Antidiabetic Agents Studies
- Life Sciences › Agricultural and Biological Sciences › Plant Science › Phytochemistry and Biological Activities
- Keywords
- natural polyphenols, flavonoids, phenolic acids, phytochemicals, fruit peel, hypercholesterolemia, hyperglycemia, hyperlipidemia, cancer prevention, bioactive compounds, health benefits
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review