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Intolerance of Uncertainty as a Contributor to Fear and Avoidance Symptoms of Panic Attacks
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Panic disorder symptoms are persistent for 50-80% of cases even after treatment, resulting in experiences of disability and dissatisfaction in life. Previous research has focused on anxiety sensitivity (AS) and its dimensions as contributing to symptoms of panic disorder; however, recent research has suggested that intolerance of uncertainty (IU)-the tendency for a person to consider the possibility of a negative event occurring as threatening, irrespective of the actual probability of its occurrence-may also play a critical role. The current study was designed to assess the specific relationships between dimensions of IU (i.e. prospective IU and inhibitory IU) and the fear and avoidance symptoms associated with panic disorder. Participants included 122 community members (81% women) with a history of at least one panic attack who participated in a larger study on fear. Participants completed measures of AS, IU, and panic disorder symptoms. Correlation and regression analyses supported a significant and substantial relationship between AS, inhibitory IU, and panic disorder symptoms. Inhibitory IU accounted for relatively more variance in avoidance symptoms related to panic disorder than did the fears of physical sensations dimension of AS. As such, further investigation of the role of IU in panic disorder symptoms appears warranted. Comprehensive results, implications, and directions for future research are discussed.
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“The IUS-12 has been found to have excellent internal consistency of α = 0.93 for the full scale and good internal consistency for subscale scores α = 0.89 (prospective IU) and α = 0.89 (inhibitory IU) (Carleton et al., 2013).”
From Behind the masks: A cross-sectional study on intolerance of uncertainty, perceived vulnerability to disease and psychological flexibility in relation to state anxiety and wellbeing during the COVID-19 pandemic (2021) · cites this paper as Carleton et al., 2013
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“However, evidence has since accumulated that IU is common across multiple emotional disorders, including obsessive compulsive disorder (OCD, Holaway, Heimberg, & Coles, 2006;Tolin, Abramowitz, Brigidi, & Foa, 2003), social anxiety (Boelen & Reijntjes, 2009;Carleton, Collimore, & Asmundson, 2010;Riskind, Tzur, Williams, Mann, & Shahar, 2007), panic disorder and agoraphobia (Carleton, Hackl, Fetzner”
From The search for universal transdiagnostic and trans-therapy change processes: Evidence for intolerance of uncertainty (2016) · cites this paper as Carleton, Hackl, Fetzner, & McEvoy, 2013
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“A significant and substantial relationship between the IU inhibitory dimension and panic symptom severity was reported in a community sample.12”
From Impact of mindfulness-based cognitive therapy on intolerance of uncertainty in patients with panic disorder (2016) · cites this paper as [12]
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A taxometric analysis of panic disorder
Hall, C. A., Broman‐Fulks, J. J., Holden, C. J., & Bergman, S. M. (2024) · Cognitive Behaviour Therapy · doi:10.1080/16506073.2024.2423656 · Cited by 1
Zahrayi, T., Yousefi, F., & Saed, O. (2019) · Shenakht Journal of Psychology and Psychiatry · doi:10.29252/shenakht.6.1.138 · Cited by 1
Metadata
- Authors
- Carleton, R. N., Fetzner, M. G., Hackl, J. L., & McEvoy, P.
- Affiliations
- University of Regina (CA)
- The University of Western Australia (AU)
- Corresponding author
- Carleton, R. Nicholas
- Venue
- Cognitive Behaviour Therapy
- Publisher
- Informa UK Limited
- Published
- 2013-12
- Volume
- 42
- Issue
- 4
- Pages
- 328-341
- ISSN
- 1650-6073 (ISSN-L)
- 1651-2316
- OpenAlex
- W2085975433
- Semantic Scholar
- c368aa76115f7d88557f2b68817ff7481dd57df4
- Cited by
- 126
- References
- 58
- Citations by year
- 2026: 4 · 2025: 6 · 2024: 5 · 2023: 10 · 2022: 12 · 2021: 7 · 2020: 8 · 2019: 26 · 2018: 5 · 2017: 12 · 2016: 21 · 2015: 4 · 2014: 6
- FWCI
- 13.97
- Type
- journal article
- Language
- en
- Open access
- green
- hdl.handle.net
- Locations
- Cognitive Behaviour Therapy (publishedVersion)
- PubMed (publishedVersion)
- eSpace (Curtin University) (submittedVersion)
- UWA Profiles and Research Repository (UWA) (submittedVersion)
- Topics
- Social Sciences › Psychology › Experimental and Cognitive Psychology › Anxiety, Depression, Psychometrics, Treatment, Cognitive Processes
- Health Sciences › Medicine › Psychiatry and Mental health › Psychosomatic Disorders and Their Treatments
- Social Sciences › Psychology › Clinical Psychology › COVID-19 and Mental Health
- Keywords
- intolerance of uncertainty, panic disorder, anxiety sensitivity, inhibitory intolerance of uncertainty, avoidance symptoms, panic attacks
- MeSH terms
- Adolescent, Adult, Aged, Anxiety, Fear, Female, Humans, Male, Middle Aged, Panic Disorder, Uncertainty
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