Plant derived edible nanoparticles as a new therapeutic approach against diseases

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Edible ginger-derived nanoparticles: A novel therapeutic approach for the prevention and treatment of inflammatory bowel disease and colitis-associated cancer

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Ginseng-derived nanoparticles alter macrophage polarization to inhibit melanoma growth

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Edible Ginger-derived Nano-lipids Loaded with Doxorubicin as a Novel Drug-delivery Approach for Colon Cancer Therapy

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Plant-derived exosome-like nanoparticles and their therapeutic activities

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Natural exosome-like nanovesicles from edible tea flowers suppress metastatic breast cancer via ROS generation and microbiota modulation

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Extracellular Vesicles—Connecting Kingdoms

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Strawberry-Derived Exosome-Like Nanoparticles Prevent Oxidative Stress in Human Mesenchymal Stromal Cells

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Identification of exosome-like nanoparticle-derived microRNAs from 11 edible fruits and vegetables

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‘Green’ nanotherapeutics from tea leaves for orally targeted prevention and alleviation of colon diseases

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Oral Administration of ginger-derived Nanolipids Loaded With siRNA As a Novel Approach for Efficient siRNA Drug Delivery to Treat Ulcerative Colitis

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Isolation of cabbage exosome-like nanovesicles and investigation of their biological activities in human cells

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Oral administration of turmeric-derived exosome-like nanovesicles with anti-inflammatory and pro-resolving bioactions for murine colitis therapy

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Plant-Derived Exosome-Like Nanovesicles: Current Progress and Prospects

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Emerging Prospects of Exosomes for Cancer Treatment: From Conventional Therapy to Immunotherapy

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Arrowtail RNA for Ligand Display on Ginger Exosome-like Nanovesicles to Systemic Deliver siRNA for Cancer Suppression

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Advances in plant-derived edible nanoparticle-based lipid nano-drug delivery systems as therapeutic nanomedicines

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Exosome-like nanoparticles derived from fruits, vegetables, and herbs: innovative strategies of therapeutic and drug delivery

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Oral Delivery of Nanoparticles Loaded With Ginger Active Compound, 6-Shogaol, Attenuates Ulcerative Colitis and Promotes Wound Healing in a Murine Model of Ulcerative Colitis

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Biological properties of plant-derived extracellular vesicles

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Plant-Derived Extracellular Vesicles as Therapeutic Nanocarriers

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Nano-hydroxyapatite use in dentistry: a systematic review

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Nanoparticle-Based Oral Drug Delivery Systems Targeting the Colon for Treatment of Ulcerative Colitis

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Plant Extracellular Vesicles and Nanovesicles: Focus on Secondary Metabolites, Proteins and Lipids with Perspectives on Their Potential and Sources

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Extracellular vesicles as key mediators of plant–microbe interactions

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Edible exosome-like nanoparticles from portulaca oleracea L mitigate DSS-induced colitis via facilitating double-positive CD4+CD8+T cells expansion

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Protein biocargo of citrus fruit-derived vesicles reveals heterogeneous transport and extracellular vesicle populations

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Bitter melon derived extracellular vesicles enhance the therapeutic effects and reduce the drug resistance of 5-fluorouracil on oral squamous cell carcinoma

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Grapefruit-derived extracellular vesicles as a promising cell-free therapeutic tool for wound healing

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Anti‐melanogenic effects of extracellular vesicles derived from plant leaves and stems in mouse melanoma cells and human healthy skin

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Blueberry-Derived Exosome-Like Nanoparticles Counter the Response to TNF-α-Induced Change on Gene Expression in EA.hy926 Cells

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A cost-effective polyethylene glycol-based method for the isolation of functional edible nanoparticles from ginger rhizomes

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Antioxidative Effects of Carrot-Derived Nanovesicles in Cardiomyoblast and Neuroblastoma Cells

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The Antioxidant Effect of Small Extracellular Vesicles Derived from Aloe vera Peels for Wound Healing

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Therapeutic biomaterials based on extracellular vesicles: classification of bio‐engineering and mimetic preparation routes

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Exosome-like Nanovesicles Isolated from Citrus limon L. Exert Antioxidative Effect

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Plant‐derived exosome‐like nanoparticles: A concise review on its extraction methods, content, bioactivities, and potential as functional food ingredient

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Use of Nanovesicles from Orange Juice to Reverse Diet-Induced Gut Modifications in Diet-Induced Obese Mice

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Exosome nanovesicles: A potential carrier for therapeutic delivery

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Exosomes Engineering and Their Roles as Therapy Delivery Tools, Therapeutic Targets, and Biomarkers

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Scalable Production and Isolation of Extracellular Vesicles: Available Sources and Lessons from Current Industrial Bioprocesses

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Garlic (Allium sativum)-derived SEVs inhibit cancer cell proliferation and induce caspase mediated apoptosis

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Biological properties and therapeutic effects of plant-derived nanovesicles

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Plant-Derived Extracellular Vesicles and Their Exciting Potential as the Future of Next-Generation Drug Delivery

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Apple-Derived Nanoparticles Modulate Expression of Organic-Anion-Transporting Polypeptide (OATP) 2B1 in Caco-2 Cells

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Plant-derived extracellular vesicles (PDEVs) in nanomedicine for human disease and therapeutic modalities

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Panax ginseng-Derived Extracellular Vesicles Facilitate Anti-Senescence Effects in Human Skin Cells: An Eco-Friendly and Sustainable Way to Use Ginseng Substances

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The Emerging Role of Plant-Derived Exosomes-Like Nanoparticles in Immune Regulation and Periodontitis Treatment

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Natural Product-Based Nanomedicine in Treatment of Inflammatory Bowel Disease

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Plant-Derived Edible Nanoparticles and miRNAs: Emerging Frontier for Therapeutics and Targeted Drug-Delivery

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Edible plant-derived exosomal microRNAs: Exploiting a cross-kingdom regulatory mechanism for targeting SARS-CoV-2

Kalarikkal, S. P., & Sundaram, G. M. (2021) · Toxicology and Applied Pharmacology · doi:10.1016/j.taap.2021.115425 · Cited by 137

Ginger nanoparticles mediated induction of Foxa2 prevents high-fat diet-induced insulin resistance

Kumar, A., Sundaram, K., Teng, Y., Mu, J., Sriwastva, M. K., Zhang, L., Hood, J. L., Yan, J., Zhang, X., Park, J. W., et al. (2022) · Theranostics · doi:10.7150/thno.62514 · Cited by 127

Characterization of and isolation methods for plant leaf nanovesicles and small extracellular vesicles

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Therapeutic miRNA-Enriched Extracellular Vesicles: Current Approaches and Future Prospects

Munir, J., Yoon, J. K., & Ryu, S. (2020) · Cells · doi:10.3390/cells9102271 · Cited by 125

Ginseng-derived nanoparticles induce skin cell proliferation and promote wound healing

Yang, S., Lu, S., Ren, L., Bian, S., Zhao, D., Liu, M., & Wang, J. (2022) · Journal of Ginseng Research · doi:10.1016/j.jgr.2022.07.005 · Cited by 127

Advanced Phytochemical-Based Nanocarrier Systems for the Treatment of Breast Cancer

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Curcumin Nanocrystal/pH-Responsive Polyelectrolyte Multilayer Core–Shell Nanoparticles for Inflammation-Targeted Alleviation of Ulcerative Colitis

Oshi, M. A., Lee, J., Naeem, M., Hasan, N., Kim, J., Kim, H. J., Lee, E. H., Jung, Y., & Yoo, J. (2020) · Biomacromolecules · doi:10.1021/acs.biomac.0c00589 · Cited by 112

A biomimetic nanocomposite made of a ginger-derived exosome and an inorganic framework for high-performance delivery of oral antibodies

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Plant-Derived Exosome-like Nanoparticles for Biomedical Applications and Regenerative Therapy

Sarasati, A., Syahruddin, M. H., Nuryanti, A., Ana, I. D., Barlian, A., Wijaya, C. H., Ratnadewi, D., Wungu, T. D. K., & Takemori, H. (2023) · Biomedicines · doi:10.3390/biomedicines11041053 · Cited by 118

The Therapeutic Potential and Clinical Significance of Exosomes as Carriers of Drug Delivery System

Li, T., Li, X., Han, G., Liang, M., Yang, Z., Zhang, C., Huang, S., Tai, S., & Yu, S. (2022) · Pharmaceutics · doi:10.3390/pharmaceutics15010021 · Cited by 110

Biomanufacturing of Tomato-Derived Nanovesicles

Ramesh, B., Ramos, A. P., Fiume, I., Manno, M., Raccosta, S., Turiák, L., Sugár, S., Adamo, G., Csizmadia, T., & Pòcsfalvi, G. (2020) · Foods · doi:10.3390/foods9121852 · Cited by 110

Eating microRNAs: pharmacological opportunities for cross‐kingdom regulation and implications in host gene and gut microbiota modulation

del Pozo‐Acebo, L., Hazas, M. L. D. L., Margollés, A., Dávalos, A., & García‐Ruiz, A. (2021) · British Journal of Pharmacology · doi:10.1111/bph.15421 · Cited by 105

Cytotoxic Effects of Plant Sap-Derived Extracellular Vesicles on Various Tumor Cell Types

Kim, K., Yoo, H. J., Jung, J., Lee, R., Hyun, J., Park, J., Na, D., & Yeon, J. H. (2020) · Journal of Functional Biomaterials · doi:10.3390/jfb11020022 · Cited by 105

Advances in Bioactivity of MicroRNAs of Plant-Derived Exosome-Like Nanoparticles and Milk-Derived Extracellular Vesicles

Li, D., Yao, X., Yue, J., Fang, Y., Cao, G., Midgley, A. C., Nishinari, K., & Yang, Y. (2022) · Journal of Agricultural and Food Chemistry · doi:10.1021/acs.jafc.2c00631 · Cited by 106

Cucumber-Derived Exosome-like Vesicles and PlantCrystals for Improved Dermal Drug Delivery

Abraham, A. M., Wiemann, S., Ambreen, G., Zhou, J., Engelhardt, K. H., Brüßler, J., Bakowsky, U., Li, S., Mandić, R., Pòcsfalvi, G., et al. (2022) · Pharmaceutics · doi:10.3390/pharmaceutics14030476 · Cited by 102

Momordica charantia Exosome-Like Nanoparticles Exert Neuroprotective Effects Against Ischemic Brain Injury via Inhibiting Matrix Metalloproteinase 9 and Activating the AKT/GSK3β Signaling Pathway

Cai, H., Huang, L., Hong, R., Song, J., Guo, X., Zhou, W., Hu, Z., Wang, W., Wang, Y., Shen, J., et al. (2022) · Frontiers in Pharmacology · doi:10.3389/fphar.2022.908830 · Cited by 103

Celery ( Apium graveolens L.) Exosome-like Nanovesicles as a New-Generation Chemotherapy Drug Delivery Platform against Tumor Proliferation

Lu, X., Han, Q., Chen, J., Wu, T., Cheng, Y., Li, F., & Xia, W. (2023) · Journal of Agricultural and Food Chemistry · doi:10.1021/acs.jafc.2c07760 · Cited by 102

Exosomes in Food: Health Benefits and Clinical Relevance in Diseases

Munir, J., Lee, M., & Ryu, S. (2019) · Advances in Nutrition · doi:10.1093/advances/nmz123 · Cited by 100

Oral Gavage of Ginger Nanoparticle-Derived Lipid Vectors Carrying Dmt1 siRNA Blunts Iron Loading in Murine Hereditary Hemochromatosis

Wang, X., Zhang, M., Flores, S. R. L., Woloshun, R. R., Yang, C., Yin, L., Xiang, P., Xu, X., Garrick, M. D., Vidyasagar, S., et al. (2019) · Molecular Therapy · doi:10.1016/j.ymthe.2019.01.003 · Cited by 99

Characterization of three different types of extracellular vesicles and their impact on bacterial growth

Yu, S., Zhao, Z., Xu, X., Li, M., & Li, P. (2018) · Food Chemistry · doi:10.1016/j.foodchem.2018.08.059 · Cited by 99

Novel concept of exosome-like liposomes for the treatment of Alzheimer's disease

Fernandes, M. S., Lopes, I., Magalhães, L., Sárria, M. P., Machado, R., Sousa, J. C., Botelho, C., Teixeira, J. A., & Gomes, A. C. (2021) · Journal of Controlled Release · doi:10.1016/j.jconrel.2021.06.018 · Cited by 97

Extracellular Vesicles Derived From Citrus sinensis Modulate Inflammatory Genes and Tight Junctions in a Human Model of Intestinal Epithelium

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Ginger: a representative material of herb-derived exosome-like nanoparticles

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