Neural basis and biological function of masking by light in mammals: suppression of melatonin and locomotor activity
Abstract
Light influences mammalian circadian rhythms in two different ways: (1) It entrains endogenous oscillators (clocks), which regulate physiology and behavior; and (2) it affects directly and often immediately physiology and behavior (these effects are also referred to as masking). Masking effects of light on pineal melatonin, locomotor activity, and the sleep-wake cycle in mammals and man are reviewed. They seem to represent a universal response in this group. The review reveals that the mechanism of photic inhibition of melatonin is fairly well understood, whereas only little is known about the influence of light on other circadian rhythm outputs, such as locomotor activity.
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Locomotor activity rhythms and molecular rhythms in mice change with alterations in the light/dark cycle.
“For example, locomotor activity rhythms and molecular rhythms in mice change with alterations in the light/dark cycle (Redlin, 2001).”
From Circadian genes, rhythms and the biology of mood disorders (2007) · cites this paper as Redlin, 2001
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Vollrath, L., Seidel, A., Huesgen, A., et al. (1989) · Neuroscience Letters · doi:10.1016/0304-3940(89)90417-5 · Cited by 23 · see citing works
Suprachiasmatic Nuclei Lesions Do Not Eliminate Homeostatic Thermoregulatory Responses in Rats
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Activity Patterns of Kangaroo Rats — Granivores in a Desert Habitat
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Constant Routines and ‘Purification’ Methods: Do They Measure the Same Thing?
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Is “Masking” an Appropriate Term?
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Circadian genes, rhythms and the biology of mood disorders
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Modulation of locomotor activity in larval zebrafish during light adaptation
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Van der Heijden, K. B., Smits, M. G., Someren, E. J. W. V., & Boudewijn Gunning, W. (2005) · Chronobiology International · doi:10.1081/cbi-200062410 · Cited by 269 · see citing works
Kronfeld-Schor, N., Dominoni, D., de la Iglesia, H., Levy, O., Herzog, E. D., Dayan, T., & Helfrich-Forster, C. (2013) · Proceedings of the Royal Society B: Biological Sciences · doi:10.1098/rspb.2012.3088 · Cited by 245 · see citing works
Circadian rhythms in glucose and lipid metabolism in nocturnal and diurnal mammals
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Food-anticipatory circadian rhythms: concepts and methods
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Non-circadian direct effects of light on sleep and alertness: Lessons from transgenic mouse models
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Ashkenazy, T., Einat, H., & Kronfeld-Schor, N. (2009) · The International Journal of Neuropsychopharmacology · doi:10.1017/s1461145708009115 · Cited by 81 · see citing works
Loss of dopamine disrupts circadian rhythms in a mouse model of Parkinson's disease
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Strong resetting of the mammalian clock by constant light followed by constant darkness
Chen, R., Seo, D.-O., Bell, E., von Gall, C., & Lee, C. (2008) · The Journal of Neuroscience · doi:10.1523/jneurosci.2191-08.2008 · Cited by 53 · see citing works
- Authors
- Redlin, U.
- Affiliations
- University of Stuttgart (DE)
- Corresponding author
- Redlin, Uwe
- Venue
- Chronobiology International
- Publisher
- Informa UK Limited
- Published
- 2001-01
- Volume
- 18
- Issue
- 5
- Pages
- 737-758
- ISSN
- 0742-0528 (ISSN-L)
- 1525-6073
- OpenAlex
- W2162570080
- Cited by
- 170
- References
- 125
- Citations by year
- 2026: 2 · 2025: 5 · 2024: 12 · 2023: 7 · 2022: 7 · 2021: 9 · 2020: 6 · 2019: 7 · 2018: 10 · 2017: 6 · 2016: 10 · 2015: 13 · 2014: 6 · 2013: 9 · 2012: 6
- FWCI
- 1.19
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- Chronobiology International (publishedVersion)
- PubMed (publishedVersion)
- Topics
- Life Sciences › Neuroscience › Endocrine and Autonomic Systems › Circadian rhythm and melatonin
- Life Sciences › Neuroscience › Cognitive Neuroscience › Sleep and Wakefulness Research
- Physical Sciences › Environmental Science › Global and Planetary Change › Impact of Light on Environment and Health
- Keywords
- light masking, melatonin suppression, pineal gland, locomotor activity, sleep-wake cycle, circadian rhythm, light entrainment, endogenous oscillator, circadian clock, mammals
- MeSH terms
- Animals, Chronobiology Phenomena, Circadian Rhythm, Geniculate Bodies, Humans, Light, Melatonin, Motor Activity, Nervous System Physiological Phenomena, Pineal Gland, Preoptic Area, Sleep, Suprachiasmatic Nucleus, Visual Cortex, Photoreceptor Cells, Vertebrate
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
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