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Inflammatory monocytes recruited after skeletal muscle injury switch into antiinflammatory macrophages to support myogenesis
Open accessAbstract
Macrophages (MPs) are important for skeletal muscle regeneration in vivo and may exert beneficial effects on myogenic cell growth through mitogenic and antiapoptotic activities in vitro. However, MPs are highly versatile and may exert various, and even opposite, functions depending on their activation state. We studied monocyte (MO)/MP phenotypes and functions during skeletal muscle repair. Selective labeling of circulating MOs by latex beads in CX3CR1GFP/+ mice showed that injured muscle recruited only CX3CR1lo/Ly-6C+ MOs from blood that exhibited a nondividing, F4/80lo, proinflammatory profile. Then, within muscle, these cells switched their phenotype to become proliferating antiinflammatory CX3CR1hi/Ly-6C− cells that further differentiated into F4/80hi MPs. In vitro, phagocytosis of muscle cell debris induced a switch of proinflammatory MPs toward an antiinflammatory phenotype releasing transforming growth factor β1. In co-cultures, inflammatory MPs stimulated myogenic cell proliferation, whereas antiinflammatory MPs exhibited differentiating activity, assessed by both myogenin expression and fusion into myotubes. Finally, depletion of circulating MOs in CD11b–diphtheria toxin receptor mice at the time of injury totally prevented muscle regeneration, whereas depletion of intramuscular F4/80hi MPs at later stages reduced the diameter of regenerating fibers. In conclusion, injured skeletal muscle recruits MOs exhibiting inflammatory profiles that operate phagocytosis and rapidly convert to antiinflammatory MPs that stimulate myogenesis and fiber growth.
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“A number of studies have shown that reduction of the number of monocytes available to participate in the response following muscle injury via depletion of circulating cells results in slowed removal of cellular debris and delayed muscle tissue remodeling [112–114].”
From Macrophage polarization: an opportunity for improved outcomes in biomaterials and regenerative medicine (2012) · cites this paper as [112]
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“For example, IL-10 secreted by M2 macrophages is known both to drive a transition from an M1 to an M2 phenotype as well as to promote the fusion and maturation of myotubes [112,125].”
From Macrophage polarization: an opportunity for improved outcomes in biomaterials and regenerative medicine (2012) · cites this paper as [112]
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“These studies showed that the timing of inflammatory responses can have profound effects on the kinetics and extent of regeneration69, findings confirmed by experiments using antibodies to block inflammatory cytokines70,71.”
From The central role of muscle stem cells in regenerative failure with aging (2015) · cites this paper as [69]
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“Accumulating evidence indicates that Mp are critical orchestrators in healing of many tissues, including skin (3,4,7,48).”
From Sustained Inflammasome Activity in Macrophages Impairs Wound Healing in Type 2 Diabetic Humans and Mice (2014) · cites this paper as [3]
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Cites
Alternative activation of macrophages
Gordon, S. (2003) · Nature Reviews Immunology · doi:10.1038/nri978 · Cited by 6,189
Monocyte and macrophage heterogeneity
Gordon, S., & Taylor, P. R. (2005) · Nature Reviews Immunology · doi:10.1038/nri1733 · Cited by 5,190
Cytokine-mediated regulation of CXCR4 expression in human neutrophils
Nagase, H., Miyamasu, M., Yamaguchi, M., Imanishi, M., Tsuno, N. H., Matsushima, K., Yamamoto, K., Morita, Y., & Hirai, K. (2002) · Journal of Leukocyte Biology · doi:10.1189/jlb.71.4.711 · Cited by 4,713
Obesity induces a phenotypic switch in adipose tissue macrophage polarization
Lumeng, C. N., Bodzin, J. L., & Saltiel, A. R. (2007) · Journal of Clinical Investigation · doi:10.1172/jci29881 · Cited by 4,664
The peroxisome proliferator-activated receptor-γ is a negative regulator of macrophage activation
Ricote, M., Li, A. C., Willson, T. M., Kelly, C. J., & Glass, C. K. (1998) · Nature · doi:10.1038/34178 · Cited by 3,525
Blood Monocytes Consist of Two Principal Subsets with Distinct Migratory Properties
Geissmann, F., Jung, S., & Littman, D. R. (2003) · Immunity · doi:10.1016/s1074-7613(03)00174-2 · Cited by 3,504
Points of control in inflammation
Nathan, C. (2002) · Nature · doi:10.1038/nature01320 · Cited by 2,738
Resolution of inflammation: the beginning programs the end
Serhan, C. N., & Savill, J. (2005) · Nature Immunology · doi:10.1038/ni1276 · Cited by 2,552
Stein, M., Keshav, S., Harris, N., & Gordon, S. (1992) · The Journal of experimental medicine · doi:10.1084/jem.176.1.287 · Cited by 1,960
van Rooijen, N., & Sanders, A. (1994) · Journal of Immunological Methods · doi:10.1016/0022-1759(94)90012-4 · Cited by 1,763
Flagged first, then by citations
Research works printed but not linked: 5
- 1996, J. Anat., 188, 17
- 2006, J. Leukoc. Biol., 81, 775
- 2004, FASEB J., 19, 413
- 2006, Nat. Immunol., 7, 265
- 2004, Proc. Natl. Acad. Sci. USA., 102, 99
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He, D., Kou, X., Luo, Q., Yang, R., Liu, D., Wang, X., Song, Y., Cao, H., Zeng, M., Gan, Y., et al. (2014) · Journal of Dental Research · doi:10.1177/0022034514553817 · Cited by 148
Chronic alcohol ingestion modulates hepatic macrophage populations and functions in mice
Wang, M., You, Q., Lor, K., Chen, F., Gao, B., & Ju, C. (2014) · Journal of Leukocyte Biology · doi:10.1189/jlb.6a0114-004rr · Cited by 151
Contreras, O., Rebolledo, D. L., Oyarzún, J. E., Olguín, H. C., & Brandan, E. (2016) · Cell and Tissue Research · doi:10.1007/s00441-015-2343-0 · Cited by 154
Fang, W., Zhai, X., Han, D., Xiong, X., Wang, T., Zeng, X., He, S., Liu, R., Miyata, M., Xu, B., et al. (2018) · Theranostics · doi:10.7150/thno.24475 · Cited by 148
Targeting Microglia and Macrophages: A Potential Treatment Strategy for Multiple Sclerosis
Wang, J., Wang, J., Wang, J., Yang, B., Weng, Q., & He, Q. (2019) · Frontiers in Pharmacology · doi:10.3389/fphar.2019.00286 · Cited by 154
Fibroadipogenic progenitors are responsible for muscle loss in limb girdle muscular dystrophy 2B
Hogarth, M. W., Defour, A., Lazarski, C. A., Gallardo, E., Díaz‐Manera, J., Partridge, T. A., Nagaraju, K., & Jaiswal, J. K. (2019) · Nature Communications · doi:10.1038/s41467-019-10438-z · Cited by 147
Intramuscular mechanisms of overtraining
Cheng, A. J., Jude, B., & Lanner, J. T. (2020) · Redox Biology · doi:10.1016/j.redox.2020.101480 · Cited by 176
Awojoodu, A. O., Ogle, M. E., Sefcik, L. S., Bowers, D. T., Martin, K. S., Brayman, K. L., Lynch, K. R., Peirce, S. M., & Botchwey, E. A. (2013) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1221309110 · Cited by 147
Signaling pathways in macrophages: molecular mechanisms and therapeutic targets
Li, M., Wang, M., Wen, Y., Zhang, H., Zhao, G., & Gao, Q. (2023) · MedComm · doi:10.1002/mco2.349 · Cited by 165
Iron levels in polarized macrophages: regulation of immunity and autoimmunity
Recalcati, S., Locati, M., Gammella, E., Invernizzi, P., & Cairo, G. (2012) · Autoimmunity Reviews · doi:10.1016/j.autrev.2012.03.003 · Cited by 150
Biological properties and therapeutic effects of plant-derived nanovesicles
Gioia, S. D., Hossain, M. N., & Conese, M. (2020) · Open Medicine · doi:10.1515/med-2020-0160 · Cited by 149
Li, B., Castaño, A. P., Hudson, T. E., Nowlin, B. T., Lin, S., Bonventre, J. V., Swanson, K. D., & Duffield, J. S. (2010) · The FASEB Journal · doi:10.1096/fj.10-154757 · Cited by 146
Kumar, R., Mickael, C. S., Kassa, B., Gebreab, L., Robinson, J. C., Koyanagi, D. E., Sanders, L., Barthel, L., Meadows, C. A., Fox, D. L., et al. (2017) · Nature Communications · doi:10.1038/ncomms15494 · Cited by 143
The privileged immunity of immune privileged organs: the case of the eye
Benhar, I., London, A., & Schwartz, M. (2012) · Frontiers in Immunology · doi:10.3389/fimmu.2012.00296 · Cited by 157
High-Content Quantification of Single-Cell Immune Dynamics
Junkin, M., Kaestli, A. J., Zhang, C., Jordi, C., Albayrak, C., Hoffmann, A., & Tay, S. (2016) · Cell Reports · doi:10.1016/j.celrep.2016.03.033 · Cited by 147
Innate immune activation in obesity
Lumeng, C. N.-K. (2012) · Molecular Aspects of Medicine · doi:10.1016/j.mam.2012.10.002 · Cited by 147
Biomaterial-based delivery for skeletal muscle repair
Cezar, C. A., & Mooney, D. (2014) · Advanced Drug Delivery Reviews · doi:10.1016/j.addr.2014.09.008 · Cited by 127
Macrophages with regulatory functions, a possible new therapeutic perspective in autoimmune diseases
Benedetto, P. D., Ruscitti, P., Vadasz, Z., Toubi, E., & Giacomelli, R. (2019) · Autoimmunity Reviews · doi:10.1016/j.autrev.2019.102369 · Cited by 140
Wermuth, P. J., & Jiménez, S. A. (2015) · Clinical and Translational Medicine · doi:10.1186/s40169-015-0047-4 · Cited by 141
Muire, P. J., Mangum, L. H., & Wenke, J. C. (2020) · Frontiers in Immunology · doi:10.3389/fimmu.2020.01056 · Cited by 152
Théret, M., Rossi, F. M. V., & Contreras, O. (2021) · Frontiers in Physiology · doi:10.3389/fphys.2021.673404 · Cited by 154
Keane, T. J., & Badylak, S. F. (2015) · Journal of Tissue Engineering and Regenerative Medicine · doi:10.1002/term.1874 · Cited by 139
Wnt Signaling in Skeletal Muscle Dynamics: Myogenesis, Neuromuscular Synapse and Fibrosis
Cisternas, P., Henríquez, J. P., Brandan, E., & Inestrosa, N. C. (2013) · Molecular Neurobiology · doi:10.1007/s12035-013-8540-5 · Cited by 141
AMPKα1‐LDH pathway regulates muscle stem cell self‐renewal by controlling metabolic homeostasis
Théret, M., Gsaier, L., Schaffer, B. E., Juban, G., Larbi, S. B., Weiss‐Gayet, M., Bultot, L., Collodet, C., Foretz, M., Dominique Desplanches, C., et al. (2017) · The EMBO Journal · doi:10.15252/embj.201695273 · Cited by 139
Self-citationGiuliani, G., Rosina, M., & Reggio, A. (2021) · FEBS Journal · doi:10.1111/febs.16080 · Cited by 144
The Basis of Muscle Regeneration
Musarò, A. (2014) · Advances in Biology · doi:10.1155/2014/612471 · Cited by 149
Chang, C.-F., Wan, J., Li, Q., Renfroe, S. C., Heller, N. M., & Wang, J. (2017) · Neurobiology of Disease · doi:10.1016/j.nbd.2017.03.016 · Cited by 136
Monocyte differentiation and macrophage polarization
Orekhov, A. N., Orekhova, V. A., Nikiforov, N. G., Myasoedova, V. A., Grechko, A. V., Romanenko, E. B., Zhang, D., & Chistiakov, D. A. (2019) · Vessel Plus · doi:10.20517/2574-1209.2019.04 · Cited by 144
Nepal, S., Tiruppathì, C., Tsukasaki, Y., Farahany, J., Mittal, M., Rehman, J., Prockop, D. J., & Malik, A. B. (2019) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1821601116 · Cited by 136
Shared signaling systems in myeloid cell-mediated muscle regeneration
Tidball, J. G., Dorshkind, K. A., & Wehling‐Henricks, M. (2014) · Development · doi:10.1242/dev.098285 · Cited by 151
Pericytes in the myovascular niche promote post-natal myofiber growth and satellite cell quiescence
Kostallari, E., Baba‐Amer, Y., Alonso‐Martín, S., Ngoh-Melame, P., Relaix, F., Lafuste, P., & Gherardi, R. K. (2015) · Development · doi:10.1242/dev.115386 · Cited by 140
Self-citationOrigins and tissue‐context‐dependent fates of blood monocytes
Varol, C., Yona, S., & Jung, S. (2008) · Immunology and Cell Biology · doi:10.1038/icb.2008.90 · Cited by 135
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Greising, S. M., Rivera, J. C., Goldman, S. M., Watts, A., Aguilar, C. A., & Corona, B. T. (2017) · Scientific Reports · doi:10.1038/s41598-017-13306-2 · Cited by 136
Multiscale analysis of a regenerative therapy for treatment of volumetric muscle loss injury
Aguilar, C. A., Greising, S. M., Watts, A., Goldman, S. M., Peragallo, C., Zook, C., Larouche, J. A., & Corona, B. T. (2018) · Cell Death Discovery · doi:10.1038/s41420-018-0027-8 · Cited by 136
Heterogeneous In Vivo Behavior of Monocyte Subsets in Atherosclerosis
Świrski, F. K., Weissleder, R., & Pittet, M. J. (2009) · Arteriosclerosis Thrombosis and Vascular Biology · doi:10.1161/atvbaha.108.180521 · Cited by 139
Apoptosis in fish: environmental factors and programmed cell death
AnvariFar, H., Amirkolaie, A. K., Miandare, H. K., Ouraji, H., Jalali, M. A., & Üçüncü, S. İ. (2016) · Cell and Tissue Research · doi:10.1007/s00441-016-2548-x · Cited by 133
The Muscle Stem Cell Niche in Health and Disease
Mashinchian, O., Pisconti, A., Moal, E. L., & Bentzinger, C. F. (2017) · Current topics in developmental biology/Current Topics in Developmental Biology · doi:10.1016/bs.ctdb.2017.08.003 · Cited by 140
The gut microbiota promotes distal tissue regeneration via RORγ+ regulatory T cell emissaries
Hanna, B. S., Wang, G., Galván-Peña, S., Mann, A. O., Ramirez, R. N., Muñoz-Rojas, A. R., Smith, K., Wan, M., Benoist, C., & Mathis, D. (2023) · Immunity · doi:10.1016/j.immuni.2023.01.033 · Cited by 126
Xu, Z., You, W., Chen, W., Zhou, Y., Nong, Q., Valencak, T. G., Wang, Y., & Shan, T. (2020) · Journal of Cachexia Sarcopenia and Muscle · doi:10.1002/jcsm.12643 · Cited by 127
Zhang, J., Xiao, Z., Qu, C., Cui, W., Wang, X., & Du, J. (2014) · The Journal of Immunology · doi:10.4049/jimmunol.1303486 · Cited by 139
Expanding roles for AMPK in skeletal muscle plasticity
Mounier, R., Théret, M., Lantier, L., Foretz, M., & Viollet, B. (2015) · Trends in Endocrinology and Metabolism · doi:10.1016/j.tem.2015.02.009 · Cited by 142
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Montecucco, F., Liberale, L., Bonaventura, A., Vecchié, A., Dallegri, F., & Carbone, F. (2017) · Current Atherosclerosis Reports · doi:10.1007/s11883-017-0646-1 · Cited by 133
CC family chemokines directly regulate myoblast responses to skeletal muscle injury
Yahiaoui, L., Gvozdic, D., Danialou, G., Mack, M., & Petrof, B. J. (2008) · The Journal of Physiology · doi:10.1113/jphysiol.2008.152090 · Cited by 130
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Rigamonti, E., Touvier, T., Clementi, E., Manfredi, A., Brunelli, S., & Rovere-Querini, P. (2013) · Journal of Immunology · doi:10.4049/jimmunol.1202903 · Cited by 119
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Robbins, C. S., & Świrski, F. K. (2010) · Cellular and Molecular Life Sciences · doi:10.1007/s00018-010-0375-x · Cited by 130
Paepe, B. D., & Bleecker, J. D. (2013) · Mediators of Inflammation · doi:10.1155/2013/540370 · Cited by 136
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Gharib, S. A., Johnston, L. K., Huizar, I., Birkland, T. P., Hanson, J. F., Wang, Y., Parks, W. C., & Manicone, A. M. (2013) · Journal of Leukocyte Biology · doi:10.1189/jlb.1112587 · Cited by 133
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Nguyen, M.-H., Cheng, M., & Koh, T. J. (2011) · The Scientific World JOURNAL · doi:10.1100/tsw.2011.137 · Cited by 130
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Espino-González, E., Dalbram, E., Mounier, R., Gondin, J., Farup, J., Jessen, N., & Treebak, J. T. (2024) · Cell Metabolism · doi:10.1016/j.cmet.2024.02.014 · Cited by 141
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Shechter, R., & Schwartz, M. (2012) · Trends in Molecular Medicine · doi:10.1016/j.molmed.2012.11.007 · Cited by 137
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Ovchinnikov, D. A. (2008) · genesis · doi:10.1002/dvg.20417 · Cited by 127
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Khan, Z., Combadière, C., Authier, F., Itier, V., Lux, F., Exley, C., Mahrouf‐Yorgov, M., Decrouy, X., Moretto, P., Tillement, O., et al. (2013) · BMC Medicine · doi:10.1186/1741-7015-11-99 · Cited by 127
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Saini, J., McPhee, J. S., Al-Dabbagh, S., Stewart, C. E., & Al‐Shanti, N. (2016) · Ageing Research Reviews · doi:10.1016/j.arr.2016.03.006 · Cited by 130
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Du, H., Shih, C., Wosczyna, M. N., Mueller, A. A., Cho, J., Aggarwal, A., Rando, T. A., & Feldman, B. J. (2017) · Nature Communications · doi:10.1038/s41467-017-00522-7 · Cited by 128
He, X., Li, X., Xia, Y., Yin, Y., Wu, R., Sun, H., & Chen, F. (2019) · Acta Biomaterialia · doi:10.1016/j.actbio.2019.02.004 · Cited by 128
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Wang, X., Chen, J., Xu, J., Xie, J., Harris, D. C. H., & Zheng, G. (2021) · Frontiers in Physiology · doi:10.3389/fphys.2021.705838 · Cited by 127
Judge, S. M., Howard, T. M., Ahn, B., Ferreira, L. F., & Judge, A. R. (2013) · PLoS ONE · doi:10.1371/journal.pone.0062687 · Cited by 127
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Ceafalan, L., Popescu, B., & Hinescu, M. (2014) · BioMed Research International · doi:10.1155/2014/957014 · Cited by 134
Role of Monocytes in Heart Failure and Atrial Fibrillation
Shahid, F., Lip, G. Y. H., & Shantsila, E. (2018) · Journal of the American Heart Association · doi:10.1161/jaha.117.007849 · Cited by 124
Sequential drug delivery to modulate macrophage behavior and enhance implant integration
O’Brien, E. M., Risser, G. E., & Spiller, K. L. (2019) · Advanced Drug Delivery Reviews · doi:10.1016/j.addr.2019.05.005 · Cited by 123
The immune system and the repair of skeletal muscle.
Brunelli, S., & Rovere-Querini, P. (2008) · Pharmacological Research · doi:10.1016/j.phrs.2008.06.008 · Cited by 132
Stem cells in the hood: the skeletal muscle niche
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Patsouris, D., Cao, J.-J., Vial, G., Bravard, A., Lefai, E., Durand, A., Durand, C., Chauvin, M.-A., Laugerette, F., Debard, C., et al. (2014) · PLoS ONE · doi:10.1371/journal.pone.0110653 · Cited by 122
Distinct contextual roles for Notch signalling in skeletal muscle stem cells
Mourikis, P., & Tajbakhsh, S. (2014) · BMC Developmental Biology · doi:10.1186/1471-213x-14-2 · Cited by 120
Trichinella spiralis: nurse cell formation with emphasis on analogy to muscle cell repair
Wu, Z., Sofronić‐Milosavljević, L., Nagano, I., & Takahashi, Y. (2008) · Parasites & Vectors · doi:10.1186/1756-3305-1-27 · Cited by 123
PPARs: the vasculature, inflammation and hypertension
Duan, S. Z., Usher, M. G., & Mortensen, R. M. (2009) · Current Opinion in Nephrology & Hypertension · doi:10.1097/mnh.0b013e328325803b · Cited by 121
Capote, J. C., Kramerova, I. A., Martinez, L., Vetrone, S. A., Barton, E. R., Sweeney, H. L., Miceli, M. C., & Spencer, M. J. (2016) · The Journal of Cell Biology · doi:10.1083/jcb.201510086 · Cited by 124
Fibrocytes develop outside the kidney but contribute to renal fibrosis in a mouse model
Reich, B., Schmidbauer, K., Gomez, M. R., Hermann, F. J., Goebel, N., Brühl, H., Ketelsen, I., Talke, Y., & Mack, M. (2013) · Kidney International · doi:10.1038/ki.2013.84 · Cited by 124
Boniakowski, A. E., Kimball, A., Joshi, A., Schaller, M., Davis, F. M., denDekker, A. D., Obi, A. T., Moore, B. B., Kunkel, S. L., & Gallagher, K. A. (2018) · European Journal of Immunology · doi:10.1002/eji.201747400 · Cited by 130
García‐Bonilla, L., Faraco, G., Moore, J. M. R., Murphy, M., Racchumi, G., Srinivasan, J., Brea, D., Iadecola, C., & Anrather, J. (2016) · Journal of Neuroinflammation · doi:10.1186/s12974-016-0750-0 · Cited by 127
Engineered skeletal muscles for disease modeling and drug discovery
Wang, J., Khodabukus, A., Rao, L., VanDusen, K. W., Abutaleb, N. O., & Bursac, N. (2019) · Biomaterials · doi:10.1016/j.biomaterials.2019.119416 · Cited by 125
Matrix-bound nanovesicles recapitulate extracellular matrix effects on macrophage phenotype
Huleihel, L., Bartolacci, J. G., Dziki, J. L., Vorobyov, T., Arnold, B., Scarritt, M. E., Pineda Molina, C., LoPresti, S. T., Brown, B. N., Naranjo, J. D., et al. (2017) · Tissue Engineering Part A · doi:10.1089/ten.tea.2017.0102 · Cited by 116
Macrophage development and polarization in chronic inflammation
Motwani, M. P., & Gilroy, D. W. (2015) · Seminars in Immunology · doi:10.1016/j.smim.2015.07.002 · Cited by 119
Age-dependent alteration in muscle regeneration: the critical role of tissue niche
Barberi, L., Scicchitano, B. M., Rossi, M. D., Bigot, A., Duguez, S., Wielgosik, A., Stewart, C. E., McPhee, J. S., Conte, M., Narici, M. V., et al. (2013) · Biogerontology · doi:10.1007/s10522-013-9429-4 · Cited by 135
Garg, K., Ward, C., Rathbone, C., & Corona, B. T. (2014) · Cell and Tissue Research · doi:10.1007/s00441-014-2006-6 · Cited by 109
Zhang, C., Wang, C., Li, Y., Miwa, T., Liu, C., Cui, W., Song, W.-C., & Du, J. (2017) · Nature Communications · doi:10.1038/s41467-017-01526-z · Cited by 106
Boehler, R. M., Kuo, R., Shin, S., Goodman, A. G., Pilecki, M. A., Leonard, J. N., & Shea, L. D. (2013) · Biotechnology and Bioengineering · doi:10.1002/bit.25175 · Cited by 117
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Mokarram, N., & Bellamkonda, R. V. (2013) · Annals of Biomedical Engineering · doi:10.1007/s10439-013-0941-0 · Cited by 115
Cheng, M. L., Nakib, D., Perciani, C. T., & MacParland, S. A. (2021) · Clinical Science · doi:10.1042/cs20190654 · Cited by 130
Immune mechanisms in fibrotic interstitial lung disease
Kamiya, M., Carter, H. M., Espíndola, M. S., Doyle, T. J., Lee, J. S., Merriam, L. T., Zhang, F., Kawano-Dourado, L. B., Sparks, J. A., Hogaboam, C. M., et al. (2024) · Cell · doi:10.1016/j.cell.2024.05.015 · Cited by 130
Kim, M. H., Gorouhi, F., Ramirez, S., Granick, J. L., Byrne, B. A., Soulika, A. M., Simon, S. I., & Isseroff, R. R. (2013) · Journal of Investigative Dermatology · doi:10.1038/jid.2013.415 · Cited by 119
Chemokine receptor CX3CR1 contributes to macrophage survival in tumor metastasis
Zheng, J., Yang, M. H., Shao, J., Miao, Y.-J., Han, J., & Du, J. (2013) · Molecular Cancer · doi:10.1186/1476-4598-12-141 · Cited by 118
Alameddine, H. S., & Morgan, J. E. (2016) · Journal of Neuromuscular Diseases · doi:10.3233/jnd-160183 · Cited by 122
Muñoz‐Cánoves, P., Neves, J., & Sousa‐Victor, P. (2019) · FEBS Journal · doi:10.1111/febs.15182 · Cited by 117
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Metadata
- Authors
- Arnold, L., Henry, A., Poron, F., Baba-Amer, Y., van Rooijen, N., Plonquet, A., Gherardi, R. K., & Chazaud, B.
- Affiliations
- Inserm (FR)
- Université Paris-Est Créteil (FR)
- 1Institut National de la Santé et de la Recherche Médicale, Unité 841, Institut Mondor de Recherche Biomédicale, “Cell Interactions in the Neuromuscular System” Team, Université Paris 12 Val-de-Marne, 94000 Créteil, France
- Vrije Universiteit Amsterdam (NL)
- Assistance Publique – Hôpitaux de Paris (FR)
- Venue
- The Journal of Experimental Medicine
- Publisher
- Rockefeller University Press
- Published
- 2007-05-07
- Volume
- 204
- Issue
- 5
- Pages
- 1057-1069
- ISSN
- 0022-1007 (ISSN-L)
- 1540-9538
- PMC
- PMC2118577
- OpenAlex
- W2108723188
- Cited by
- 2,002
- References
- 82
- Citations by year
- 2026: 87 · 2025: 83 · 2024: 100 · 2023: 119 · 2022: 124 · 2021: 151 · 2020: 144 · 2019: 134 · 2018: 131 · 2017: 147 · 2016: 119 · 2015: 127 · 2014: 120 · 2013: 101 · 2012: 89
- FWCI
- 20.15
- Type
- journal article
- Language
- en
- Open access
- green
- europepmc.org
- Licence
- cc-by-nc-sa
- Locations
- The Journal of Experimental Medicine (publishedVersion)
- Europe PMC (PubMed Central) (publishedVersion, cc-by-nc-sa)
- PubMed Central (publishedVersion, cc-by-nc-sa)
- PubMed (publishedVersion)
- HAL (submittedVersion, other-oa)
- Funders
- Institut National de la Santé et de la Recherche Médicale
- Topics
- Life Sciences › Biochemistry, Genetics and Molecular Biology › Molecular Biology › Muscle Physiology and Disorders
- Health Sciences › Medicine › Surgery › Wound Healing and Treatments
- Life Sciences › Immunology and Microbiology › Immunology › Immune cells in cancer
- Keywords
- inflammatory monocytes, macrophage polarization, skeletal muscle regeneration, myogenesis, CX3CR1, Ly6C, F4/80, TGF-β1, myotube formation, monocyte depletion, muscle damage
- MeSH terms
- CX3C Chemokine Receptor 1, Animals, Cell Differentiation, Humans, Immunohistochemistry, Macrophages, Mice, Mutant Strains, Microspheres, Monocytes, Phagocytosis, DNA Primers, Muscle, Skeletal, Receptors, Chemokine, Reverse Transcriptase Polymerase Chain Reaction, Muscle Development, CD11b Antigen, Green Fluorescent Proteins, Mice
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