The DOI matches its Crossref record; 82 of the 82 references it cites were found in a registry or an index.
Inflammatory monocytes recruited after skeletal muscle injury switch into antiinflammatory macrophages to support myogenesis
Open accessAbstract
Macrophages (MPs) are important for skeletal muscle regeneration in vivo and may exert beneficial effects on myogenic cell growth through mitogenic and antiapoptotic activities in vitro. However, MPs are highly versatile and may exert various, and even opposite, functions depending on their activation state. We studied monocyte (MO)/MP phenotypes and functions during skeletal muscle repair. Selective labeling of circulating MOs by latex beads in CX3CR1GFP/+ mice showed that injured muscle recruited only CX3CR1lo/Ly-6C+ MOs from blood that exhibited a nondividing, F4/80lo, proinflammatory profile. Then, within muscle, these cells switched their phenotype to become proliferating antiinflammatory CX3CR1hi/Ly-6C− cells that further differentiated into F4/80hi MPs. In vitro, phagocytosis of muscle cell debris induced a switch of proinflammatory MPs toward an antiinflammatory phenotype releasing transforming growth factor β1. In co-cultures, inflammatory MPs stimulated myogenic cell proliferation, whereas antiinflammatory MPs exhibited differentiating activity, assessed by both myogenin expression and fusion into myotubes. Finally, depletion of circulating MOs in CD11b–diphtheria toxin receptor mice at the time of injury totally prevented muscle regeneration, whereas depletion of intramuscular F4/80hi MPs at later stages reduced the diameter of regenerating fibers. In conclusion, injured skeletal muscle recruits MOs exhibiting inflammatory profiles that operate phagocytosis and rapidly convert to antiinflammatory MPs that stimulate myogenesis and fiber growth.
Overview
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Integrity signals
Registry
Cites
Statistics
Verification
Claims the paper makes
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Claims other papers make about this one
Each is checked against this paper’s own text: does it say what the citing paper says it does?
In the citing paper
“A number of studies have shown that reduction of the number of monocytes available to participate in the response following muscle injury via depletion of circulating cells results in slowed removal of cellular debris and delayed muscle tissue remodeling [112–114].”
From Macrophage polarization: an opportunity for improved outcomes in biomaterials and regenerative medicine (2012) · cites this paper as [112]
In the citing paper
“For example, IL-10 secreted by M2 macrophages is known both to drive a transition from an M1 to an M2 phenotype as well as to promote the fusion and maturation of myotubes [112,125].”
From Macrophage polarization: an opportunity for improved outcomes in biomaterials and regenerative medicine (2012) · cites this paper as [112]
In the citing paper
“These studies showed that the timing of inflammatory responses can have profound effects on the kinetics and extent of regeneration69, findings confirmed by experiments using antibodies to block inflammatory cytokines70,71.”
From The central role of muscle stem cells in regenerative failure with aging (2015) · cites this paper as [69]
In the citing paper
“Accumulating evidence indicates that Mp are critical orchestrators in healing of many tissues, including skin (3,4,7,48).”
From Sustained Inflammasome Activity in Macrophages Impairs Wound Healing in Type 2 Diabetic Humans and Mice (2014) · cites this paper as [3]
Self-check
Percentages, sums and reported differences re-computed from the paper’s own numbers.
The self-check needs the paper’s full text.
Citations
Cites
Alternative activation of macrophages
Gordon, S. (2003) · Nature Reviews Immunology · doi:10.1038/nri978 · Cited by 6,189
Monocyte and macrophage heterogeneity
Gordon, S., & Taylor, P. R. (2005) · Nature Reviews Immunology · doi:10.1038/nri1733 · Cited by 5,190
Cytokine-mediated regulation of CXCR4 expression in human neutrophils
Nagase, H., Miyamasu, M., Yamaguchi, M., Imanishi, M., Tsuno, N. H., Matsushima, K., Yamamoto, K., Morita, Y., & Hirai, K. (2002) · Journal of Leukocyte Biology · doi:10.1189/jlb.71.4.711 · Cited by 4,713
Obesity induces a phenotypic switch in adipose tissue macrophage polarization
Lumeng, C. N., Bodzin, J. L., & Saltiel, A. R. (2007) · Journal of Clinical Investigation · doi:10.1172/jci29881 · Cited by 4,664
The peroxisome proliferator-activated receptor-γ is a negative regulator of macrophage activation
Ricote, M., Li, A. C., Willson, T. M., Kelly, C. J., & Glass, C. K. (1998) · Nature · doi:10.1038/34178 · Cited by 3,525
Blood Monocytes Consist of Two Principal Subsets with Distinct Migratory Properties
Geissmann, F., Jung, S., & Littman, D. R. (2003) · Immunity · doi:10.1016/s1074-7613(03)00174-2 · Cited by 3,504
Points of control in inflammation
Nathan, C. (2002) · Nature · doi:10.1038/nature01320 · Cited by 2,738
Resolution of inflammation: the beginning programs the end
Serhan, C. N., & Savill, J. (2005) · Nature Immunology · doi:10.1038/ni1276 · Cited by 2,552
Stein, M., Keshav, S., Harris, N., & Gordon, S. (1992) · The Journal of experimental medicine · doi:10.1084/jem.176.1.287 · Cited by 1,960
van Rooijen, N., & Sanders, A. (1994) · Journal of Immunological Methods · doi:10.1016/0022-1759(94)90012-4 · Cited by 1,763
Flagged first, then by citations
Research works printed but not linked: 5
- 1996, J. Anat., 188, 17
- 2006, J. Leukoc. Biol., 81, 775
- 2004, FASEB J., 19, 413
- 2006, Nat. Immunol., 7, 265
- 2004, Proc. Natl. Acad. Sci. USA., 102, 99
Cited by
Sorted by citations
Items 101–200 of 1,001
Monocytes and macrophages in tissue repair: Implications for immunoregenerative biomaterial design
Ogle, M. E., Segar, C. E., Sridhar, S., & Botchwey, E. A. (2016) · Experimental Biology and Medicine · doi:10.1177/1535370216650293 · Cited by 378
Ferrante, C. J., Pinhal-Enfield, G., Elson, G., Cronstein, B. N., Hasko, G., Outram, S., & Leibovich, S. J. (2013) · Inflammation · doi:10.1007/s10753-013-9621-3 · Cited by 375
Inflammation and Skeletal Muscle Regeneration: Leave It to the Macrophages!
Chazaud, B. (2020) · Trends in Immunology · doi:10.1016/j.it.2020.04.006 · Cited by 397
Self-citationMacrophage and Fibroblast Interactions in Biomaterial‐Mediated Fibrosis
Witherel, C. E., Abebayehu, D., Barker, T. H., & Spiller, K. L. (2019) · Advanced Healthcare Materials · doi:10.1002/adhm.201801451 · Cited by 374
Li, L., Yan, B., Shi, Y.-Q., Zhang, W.-Q., & Wen, Z.-L. (2012) · Journal of Biological Chemistry · doi:10.1074/jbc.m112.349126 · Cited by 353
“Consistent with previous studies in mice (4, 7), we further document that the depletion of macrophages in zebrafish leads to the delay of the clearance of cell debris, decrease of regeneration speed, and formation of vacuoles in the regenerating fin.”
BackgroundResultRemodeling Phenotype of Human Subcutaneous Adipose Tissue Macrophages
Bourlier, V., Zakaroff‐Girard, A., Miranville, A., Barros, S. D., Maumus, M., Sengenès, C., Galitzky, J., Lafontan, M., Karpe, F., Frayn, K. N., et al. (2008) · Circulation · doi:10.1161/circulationaha.107.724096 · Cited by 390
Mettu, P. S., Allingham, M. J., & Cousins, S. W. (2021) · Progress in Retinal and Eye Research · doi:10.1016/j.preteyeres.2020.100906 · Cited by 370
Macrophage plasticity: signaling pathways, tissue repair, and regeneration
Yan, L., Wang, J., Cai, X., Liou, Y., Shen, H., Hao, J., Huang, C., Luo, G., & He, W. (2024) · MedComm · doi:10.1002/mco2.658 · Cited by 406
Skeletal muscle fibrosis: an overview
Mahdy, M. A. A. (2018) · Cell and Tissue Research · doi:10.1007/s00441-018-2955-2 · Cited by 320
Monocyte and Macrophage Heterogeneity in the Heart
Nahrendorf, M., & Świrski, F. K. (2013) · Circulation Research · doi:10.1161/circresaha.113.300890 · Cited by 376
Liu, Z., Wang, M., Wang, X., Bu, Q., Wang, Q., Su, W., Li, L., Zhou, H., & Lü, L. (2022) · Redox Biology · doi:10.1016/j.redox.2022.102305 · Cited by 363
The chemotaxis of M1 and M2 macrophages is regulated by different chemokines
Xuan, W., Qu, Q., Zheng, B., Xiong, S., & Fan, G.-H. (2015) · Journal of Leukocyte Biology · doi:10.1189/jlb.1a0314-170r · Cited by 357
A Muscle Stem Cell Support Group: Coordinated Cellular Responses in Muscle Regeneration
Wosczyna, M. N., & Rando, T. A. (2018) · Developmental Cell · doi:10.1016/j.devcel.2018.06.018 · Cited by 363
Phenotypic Transitions of Macrophages Orchestrate Tissue Repair
Novak, M. L., & Koh, T. J. (2013) · American Journal Of Pathology · doi:10.1016/j.ajpath.2013.06.034 · Cited by 370
Madsen, D. H., Leonard, D., Masedunskas, A., Moyer, A. B., Jürgensen, H. J., Peters, D. E., Amornphimoltham, P., Selvaraj, A., Yamada, S. S., Brenner, D. A., et al. (2013) · The Journal of Cell Biology · doi:10.1083/jcb.201301081 · Cited by 353
Monocyte trafficking in acute and chronic inflammation
Ingersoll, M. A., Platt, A. M., Potteaux, S., & Randolph, G. J. (2011) · Trends in Immunology · doi:10.1016/j.it.2011.05.001 · Cited by 360
Dysregulation of monocyte/macrophage phenotype in wounds of diabetic mice
Mirza, R., & Koh, T. J. (2011) · Cytokine · doi:10.1016/j.cyto.2011.06.016 · Cited by 342
Skeletal muscle regeneration is modulated by inflammation
Yang, W., & Hu, P. (2018) · Journal of Orthopaedic Translation · doi:10.1016/j.jot.2018.01.002 · Cited by 366
Skeletal muscle stem cells in developmental versus regenerative myogenesis
Tajbakhsh, S. (2009) · Journal of Internal Medicine · doi:10.1111/j.1365-2796.2009.02158.x · Cited by 333
Tissue Stem Cells: Architects of Their Niches
Fuchs, E., & Blau, H. M. (2020) · Cell Stem Cell · doi:10.1016/j.stem.2020.09.011 · Cited by 332
Nonclassical Ly6C− Monocytes Drive the Development of Inflammatory Arthritis in Mice
Misharin, A. V., Cuda, C. M., Saber, R., Turner, J. D., Gierut, A. K., Haines, G. K., Berdnikovs, S., Filer, A. D., Clark, A. R., Buckley, C. D., et al. (2014) · Cell Reports · doi:10.1016/j.celrep.2014.09.032 · Cited by 330
Lin, S., Castaño, A. P., Nowlin, B. T., Lupher, M., & Duffield, J. S. (2009) · The Journal of Immunology · doi:10.4049/jimmunol.0901473 · Cited by 331
Tonkin, J. N., Temmerman, L., Sampson, R. D., Gallego-Colón, E., Barberi, L., Bilbao, D., Schneider, M. D., Musarò, A., & Rosenthal, N. A. (2015) · Molecular Therapy · doi:10.1038/mt.2015.66 · Cited by 328
Do antioxidant supplements interfere with skeletal muscle adaptation to exercise training?
Merry, T. L., & Ristow, M. (2015) · The Journal of Physiology · doi:10.1113/jp270654 · Cited by 341
Regulatory factors and cell populations involved in skeletal muscle regeneration
Broek, R. W. T., Grefte, S., & den Hoff, J. W. V. (2010) · Journal of Cellular Physiology · doi:10.1002/jcp.22127 · Cited by 315
Interactions between Schwann cells and macrophages in injury and inherited demyelinating disease
Martini, R., Fischer, S., López‐Vales, R., & David, S. (2008) · Glia · doi:10.1002/glia.20766 · Cited by 319
Mirza, R. E., Fang, M. M., Weinheimer-Haus, E. M., Ennis, W. J., & Koh, T. J. (2014) · Diabetes · doi:10.2337/db13-0927 · Cited by 319
“Accumulating evidence indicates that Mp are critical orchestrators in healing of many tissues, including skin (3,4,7,48).”
BackgroundSennlaub, F., Auvynet, C., Calippe, B., Lavalette, S., Poupel, L., Hu, S. J., Dominguez, E., Camelo, S., Levy, O., Guyon, E., et al. (2013) · EMBO Molecular Medicine · doi:10.1002/emmm.201302692 · Cited by 325
CSF-1 signaling mediates recovery from acute kidney injury
Zhang, M.-Z., Yao, B., Yang, S., Li, J., Wang, S., Fan, X., Yin, H., Wong, K., Miyazawa, T., Chen, J., et al. (2012) · Journal of Clinical Investigation · doi:10.1172/jci60363 · Cited by 319
Adult stem cells at work: regenerating skeletal muscle
Schmidt, M., Schüler, S. C., Hüttner, S. S., von Eyß, B., & von Maltzahn, J. (2019) · Cellular and Molecular Life Sciences · doi:10.1007/s00018-019-03093-6 · Cited by 337
Immune Modulation of Stem Cells and Regeneration
Aurora, A. B., & Olson, E. N. (2014) · Cell stem cell · doi:10.1016/j.stem.2014.06.009 · Cited by 322
Macrophages: Supportive cells for tissue repair and regeneration
Chazaud, B. (2013) · Immunobiology · doi:10.1016/j.imbio.2013.09.001 · Cited by 326
Self-citationMacrophage-based therapeutic strategies in regenerative medicine
Spiller, K. L., & Koh, T. J. (2017) · Advanced Drug Delivery Reviews · doi:10.1016/j.addr.2017.05.010 · Cited by 310
The Inflammatory Response to Skeletal Muscle Injury
Smith, C., Kruger, M. J., Smith, R. M., & Myburgh, K. H. (2008) · Sports Medicine · doi:10.2165/00007256-200838110-00005 · Cited by 323
Polarization dictates iron handling by inflammatory and alternatively activated macrophages
Corna, G., Campana, L., Pignatti, E., Castiglioni, A., Tagliafico, E., Bosurgi, L., Campanella, A., Brunelli, S., Manfredi, A. A., Apostoli, P., et al. (2010) · Haematologica · doi:10.3324/haematol.2010.023879 · Cited by 304
Endometriosis, a disease of the macrophage
Capobianco, A. (2013) · Frontiers in Immunology · doi:10.3389/fimmu.2013.00009 · Cited by 309
Exercise‐induced muscle damage: What is it, what causes it and what are the nutritional solutions?
Owens, D. J., Twist, C., Cobley, J. N., Howatson, G., & Close, G. L. (2018) · European Journal of Sport Science · doi:10.1080/17461391.2018.1505957 · Cited by 309
Macrophage Plasticity and the Role of Inflammation in Skeletal Muscle Repair
Kharraz, Y., Guerra, J., Mann, C. J., Serrano, A. L., & Muñoz‐Cánoves, P. (2013) · Mediators of Inflammation · doi:10.1155/2013/491497 · Cited by 325
Regeneration of skeletal muscle
Turner, N. J., & Badylak, S. F. (2011) · Cell and Tissue Research · doi:10.1007/s00441-011-1185-7 · Cited by 309
Villalta, S. A., Rinaldi, C., Deng, B., Liu, G., Fedor, B., & Tidball, J. G. (2011) · Human Molecular Genetics · doi:10.1093/hmg/ddq523 · Cited by 299
Exercise-dependent regulation of the tumour microenvironment
Koelwyn, G. J., Quail, D. F., Zhang, X., White, R. M., & Jones, L. W. (2017) · Nature reviews. Cancer · doi:10.1038/nrc.2017.78 · Cited by 307
Macrophage reaction against biomaterials in the mouse model–phenotypes, functions and markers
Klopfleisch, R. (2016) · Acta Biomaterialia · doi:10.1016/j.actbio.2016.07.003 · Cited by 298
Pichler, R. H., Afkarian, M., Dieter, B. P., & Tuttle, K. R. (2016) · American Journal of Physiology-Renal Physiology · doi:10.1152/ajprenal.00314.2016 · Cited by 308
Tissue regulatory T cells: regulatory chameleons
Muñoz-Rojas, A. R., & Mathis, D. (2021) · Nature Reviews Immunology · doi:10.1038/s41577-021-00519-w · Cited by 281
Regulation and dysregulation of fibrosis in skeletal muscle
Serrano, A. L., & Muñoz‐Cánoves, P. (2010) · Experimental Cell Research · doi:10.1016/j.yexcr.2010.05.035 · Cited by 302
Temporal Dynamics and Heterogeneity of Cell Populations during Skeletal Muscle Regeneration
Oprescu, S. N., Yue, F., Qiu, J., Brito, L. F., & Kuang, S. (2020) · iScience · doi:10.1016/j.isci.2020.100993 · Cited by 298
Pillon, N. J., Bilan, P. J., Fink, L. N., & Klip, A. (2013) · American Journal of Physiology-Endocrinology and Metabolism · doi:10.1152/ajpendo.00553.2012 · Cited by 299
Can the immune system be harnessed to repair the CNS?
Popovich, P. G., & Longbrake, E. E. (2008) · Nature reviews. Neuroscience · doi:10.1038/nrn2398 · Cited by 289
Macrophages prevent hemorrhagic infarct transformation in murine stroke models
Gliem, M., Mausberg, A. K., Lee, J., Simiantonakis, I., van Rooijen, N., Hartung, H., & Jander, S. (2012) · Annals of Neurology · doi:10.1002/ana.23529 · Cited by 284
London, A., Cohen, M., & Schwartz, M. (2013) · Frontiers in Cellular Neuroscience · doi:10.3389/fncel.2013.00034 · Cited by 282
Macrophages of diverse phenotypes drive vascularization of engineered tissues
Graney, P. L., Ben‐Shaul, S., Landau, S., Bajpai, A., Singh, B. S., Eager, J. M., Cohen, A. R., Levenberg, S., & Spiller, K. L. (2020) · Science Advances · doi:10.1126/sciadv.aay6391 · Cited by 286
Zhang, C., Li, Y., Wu, Y., Wang, L., Wang, X., & Du, J. (2013) · Journal of Biological Chemistry · doi:10.1074/jbc.m112.419788 · Cited by 279
“When the monocyteswere depleted inWTmice, even if the proliferation capacity of myoblasts was similar, the regeneration was deficient (6, 7).”
InfluentialMacrophage subsets and microglia in multiple sclerosis
Bogie, J. F. J., Stinissen, P., & Hendriks, J. J. A. (2014) · Acta Neuropathologica · doi:10.1007/s00401-014-1310-2 · Cited by 251
Live imaging of wound angiogenesis reveals macrophage orchestrated vessel sprouting and regression
Gurevich, D., Severn, C. E., Twomey, C., Greenhough, A., Cash, J. L., Toye, A., Mellor, H., & Martin, P. (2018) · EMBO Journal · doi:10.15252/embj.201797786 · Cited by 252
Muscle injuries and strategies for improving their repair
Laumonier, T., & Ménétrey, J. (2016) · Journal of Experimental Orthopaedics · doi:10.1186/s40634-016-0051-7 · Cited by 297
Didierlaurent, A. M., Collignon, C., Bourguignon, P., Wouters, S., Fierens, K., Fochesato, M., Dendouga, N., Langlet, C., Malissen, B., Lambrecht, B. N., et al. (2014) · The Journal of Immunology · doi:10.4049/jimmunol.1400948 · Cited by 266
Macrophages in age-related chronic inflammatory diseases
Oishi, Y., & Manabe, I. (2016) · npj Aging and Mechanisms of Disease · doi:10.1038/npjamd.2016.18 · Cited by 262
Targeting of CD163+ Macrophages in Inflammatory and Malignant Diseases
Skytthe, M. K., Graversen, J. H., & Moestrup, S. K. (2020) · International Journal of Molecular Sciences · doi:10.3390/ijms21155497 · Cited by 275
Brown, B. N., & Badylak, S. F. (2012) · Acta Biomaterialia · doi:10.1016/j.actbio.2012.10.025 · Cited by 269
Role of macrophages in peripheral nerve injury and repair
Chang, F., Wang, Y., Liu, P., Peng, J. C., Han, G., Ding, X., Wei, S., Gao, G., & Huang, K. (2019) · Neural Regeneration Research · doi:10.4103/1673-5374.253510 · Cited by 274
Lu, H., Huang, D., Saederup, N., Charo, I. F., Ransohoff, R. M., & Zhou, L. (2010) · The FASEB Journal · doi:10.1096/fj.10-171579 · Cited by 279
Monocytes: subsets, origins, fates and functions
Yona, S., & Jung, S. (2009) · Current Opinion in Hematology · doi:10.1097/moh.0b013e3283324f80 · Cited by 267
Louvet, A., Teixeira-Clerc, F., Chobert, M.-N., Deveaux, V., Pavoine, C., Zimmer, A., Pecker, F., Mallat, A., & Lotersztajn, S. (2011) · Hepatology · doi:10.1002/hep.24524 · Cited by 259
The promotion of a constructive macrophage phenotype by solubilized extracellular matrix
Sicari, B. M., Dziki, J. L., Siu, B. F., Medberry, C. J., Dearth, C. L., & Badylak, S. F. (2014) · Biomaterials · doi:10.1016/j.biomaterials.2014.06.060 · Cited by 255
Egawa, M., Mukai, K., Yoshikawa, S., Iki, M., Mukaida, N., Kawano, Y., Minegishi, Y., & Karasuyama, H. (2013) · Immunity · doi:10.1016/j.immuni.2012.11.014 · Cited by 265
Recruited Monocytes and Type 2 Immunity Promote Lung Regeneration following Pneumonectomy
Lechner, A. J., Driver, I. H., Lee, J., Conroy, C., Nagle, A., Locksley, R. M., & Rock, J. R. (2017) · Cell stem cell · doi:10.1016/j.stem.2017.03.024 · Cited by 261
Domínguez, P. M., & Ardavín, C. (2010) · Immunological Reviews · doi:10.1111/j.0105-2896.2009.00876.x · Cited by 273
Lu, H., Huang, D., Ransohoff, R. M., & Zhou, L. (2011) · The FASEB Journal · doi:10.1096/fj.10-178939 · Cited by 264
Forcina, L., Cosentino, M., & Musarò, A. (2020) · Cells · doi:10.3390/cells9051297 · Cited by 282
Understanding the Process of Fibrosis in Duchenne Muscular Dystrophy
Kharraz, Y., Guerra, J., Pessina, P., Serrano, A. L., & Muñoz‐Cánoves, P. (2014) · BioMed Research International · doi:10.1155/2014/965631 · Cited by 270
Dual and Beneficial Roles of Macrophages During Skeletal Muscle Regeneration
Chazaud, B., Brigitte, M., Yacoub‐Youssef, H., Arnold, L., Gherardi, R. K., Sonnet, C., Lafuste, P., & Chrétien, F. (2008) · Exercise and Sport Sciences Reviews · doi:10.1097/jes.0b013e318190ebdb · Cited by 270
Self-citationTwo to Tango: Dialog between Immunity and Stem Cells in Health and Disease
Naik, S., Larsen, S. B., Cowley, C. J., & Fuchs, E. V. (2018) · Cell · doi:10.1016/j.cell.2018.08.071 · Cited by 246
Monocyte/macrophage interactions with myogenic precursor cells during skeletal muscle regeneration
Saclier, M., Cuvellier, S., Magnan, M., Mounier, R., & Chazaud, B. (2013) · FEBS Journal · doi:10.1111/febs.12166 · Cited by 270
Self-citationThe effects of obesity on skeletal muscle regeneration
Akhmedov, D., & Berdeaux, R. (2013) · Frontiers in Physiology · doi:10.3389/fphys.2013.00371 · Cited by 241
Ho, A. T. V., Palla, A. R., Blake, M. R., Yucel, N. D., Wang, Y. X., Magnusson, K. E. G., Holbrook, C. A., Kraft, P. E., Delp, S. L., & Blau, H. M. (2017) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1705420114 · Cited by 248
Lu, J., Cao, Q., Zheng, D., Sun, Y., Wang, C., Yu, X., Wang, Y., Lee, V. W. S., Zheng, G., Tan, T. K., et al. (2013) · Kidney International · doi:10.1038/ki.2013.135 · Cited by 242
Antigen presentation by monocytes and monocyte-derived cells.
Randolph, G., Jakubzick, C. V., & Qu, C. (2008) · Current Opinion in Immunology · doi:10.1016/j.coi.2007.10.010 · Cited by 253
Macrophages and Immunologic Inflammation of the Kidney
Duffield, J. S. (2010) · Seminars in Nephrology · doi:10.1016/j.semnephrol.2010.03.003 · Cited by 237
Autocrine and Paracrine Angiopoietin 1/Tie-2 Signaling Promotes Muscle Satellite Cell Self-Renewal
Abou-Khalil, R., Grand, F. L., Pallafacchina, G., Valable, S., Authier, F., Rudnicki, M. A., Gherardi, R. K., Germain, S., Chrétien, F. C., Sotiropoulos, A., et al. (2009) · Cell stem cell · doi:10.1016/j.stem.2009.06.001 · Cited by 236
Self-citationPerdiguero, E., Sousa-Victor, P., Ruiz-Bonilla, V., Jardí, M., Caelles, C., Serrano, A. L., & Muñoz-Cánoves, P. (2011) · Journal of Cell Biology · doi:10.1083/jcb.201104053 · Cited by 236
The Role of Myofibroblasts in Physiological and Pathological Tissue Repair
Schuster, R., Younesi, F., Ezzo, M., & Hinz, B. (2023) · Cold Spring Harbor Perspectives in Biology · doi:10.1101/cshperspect.a041231 · Cited by 232
Latroche, C., Weiss‐Gayet, M., Muller, L., Gitiaux, C., Leblanc, P., Liot, S., Larbi, S. B., Abou-Khalil, R., Verger, N., Bardot, P., et al. (2017) · Stem Cell Reports · doi:10.1016/j.stemcr.2017.10.027 · Cited by 234
Self-citationMacrophages provide a transient muscle stem cell niche via NAMPT secretion
Ratnayake, D., Nguyen, P. D., Rossello, F. J., Wimmer, V. C., Tan, J. L., Galvis, L. A., Julier, Z., Wood, A. J., Boudier, T., Isiaku, A. I., et al. (2021) · Nature · doi:10.1038/s41586-021-03199-7 · Cited by 239
Varma, V., Yao-Borengasser, A., Rasouli, N., Nolen, G. T., Phanavanh, B., Starks, T., Gurley, C., Simpson, P., McGehee, R. E., Kern, P. A., et al. (2009) · American Journal of Physiology-Endocrinology and Metabolism · doi:10.1152/ajpendo.90885.2008 · Cited by 229
Bone-Marrow-Resident NK Cells Prime Monocytes for Regulatory Function during Infection
Askenase, M. H., Han, S., Byrd, A. L., da Fonseca, D. M., Bouladoux, N. J., Wilhelm, C., Konkel, J. E., Hand, T. W., Lacerda‐Queiroz, N., Su, X., et al. (2015) · Immunity · doi:10.1016/j.immuni.2015.05.011 · Cited by 223
Desguerre, I., Mayer, M., Leturcq, F., Barbet, J., Gherardi, R., & Christov, C. (2009) · Journal of Neuropathology and Experimental Neurology · doi:10.1097/nen.0b013e3181aa31c2 · Cited by 205
Self-citationOlingy, C. E., Emeterio, C. L. S., Ogle, M. E., Krieger, J. R., Bruce, A. C., Pfau, D. D., Jordan, B. T., Peirce, S. M., & Botchwey, E. A. (2017) · Scientific Reports · doi:10.1038/s41598-017-00477-1 · Cited by 234
Characterization of murine macrophages from bone marrow, spleen and peritoneum
Wang, C., Yu, X., Cao, Q., Wang, Y., Zheng, G., Tan, T. K., Zhao, H., Zhao, Y., Wang, Y., & Harris, D. C. (2013) · BMC Immunology · doi:10.1186/1471-2172-14-6 · Cited by 225
Phenotypic and functional switch of macrophages induced by regulatory CD4 + CD25 + T cells in mice
Liu, G., Ma, H., Qiu, L., Li, L., Cao, Y., Ma, J., & Zhao, Y. X. (2010) · Immunology and Cell Biology · doi:10.1038/icb.2010.70 · Cited by 223
Physiological roles of macrophages
Gordon, S., & Martínez‐Pomares, L. (2017) · Pflügers Archiv - European Journal of Physiology · doi:10.1007/s00424-017-1945-7 · Cited by 242
Juban, G., Saclier, M., Yacoub‐Youssef, H., Kernou, A., Arnold, L., Boisson, C., Larbi, S. B., Magnan, M., Cuvellier, S., Théret, M., et al. (2018) · Cell Reports · doi:10.1016/j.celrep.2018.10.077 · Cited by 233
Self-citationDynamics of cellular states of fibro-adipogenic progenitors during myogenesis and muscular dystrophy
Malecová, B., Gatto, S., Etxaniz, U., Passafaro, M., Cortez, A., Nicoletti, C., Giordani, L., Torcinaro, A., Bardi, M. D., Bicciato, S., et al. (2018) · Nature Communications · doi:10.1038/s41467-018-06068-6 · Cited by 221
Donnelly, D. J., Longbrake, E. E., Shawler, T. M., Kigerl, K. A., Lai, W., Tovar, C. A., Ransohoff, R. M., & Popovich, P. G. (2011) · Journal of Neuroscience · doi:10.1523/jneurosci.2114-11.2011 · Cited by 219
Transcriptome analysis of IL-10-stimulated (M2c) macrophages by next-generation sequencing
Lurier, E. B., Dalton, D., Dampier, W., Raman, P., Nassiri, S., Ferraro, N. M., Rajagopalan, R., Sarmady, M., & Spiller, K. L. (2017) · Immunobiology · doi:10.1016/j.imbio.2017.02.006 · Cited by 222
The balancing act of the liver: tissue regeneration versus fibrosis
Cordero-Espinoza, L., & Huch, M. (2018) · Journal of Clinical Investigation · doi:10.1172/jci93562 · Cited by 233
Gautier, E. L., Jakubzick, C., & Randolph, G. J. (2009) · Arteriosclerosis, Thrombosis, and Vascular Biology · doi:10.1161/atvbaha.108.180505 · Cited by 216
Dayan, V., Yannarelli, G., Billia, F., Filomeno, P., Wang, X.-H., Davies, J. E., & Keating, A. (2011) · Basic Research in Cardiology · doi:10.1007/s00395-011-0221-9 · Cited by 249
Varga, T., Mounier, R., Horváth, A., Cuvellier, S., Dumont, F., Póliska, S., Ardjoune, H., Juban, G., Nagy, L., & Chazaud, B. (2016) · The Journal of Immunology · doi:10.4049/jimmunol.1502490 · Cited by 229
Self-citationChanges in Regenerative Capacity through Lifespan
Yun, M. (2015) · International Journal of Molecular Sciences · doi:10.3390/ijms161025392 · Cited by 216
London, A., Itskovich, E., Benhar, I., Kalchenko, V., Mack, M., Jung, S., & Schwartz, M. (2011) · The Journal of Experimental Medicine · doi:10.1084/jem.20101202 · Cited by 217
Metadata
- Authors
- Arnold, L., Henry, A., Poron, F., Baba-Amer, Y., van Rooijen, N., Plonquet, A., Gherardi, R. K., & Chazaud, B.
- Affiliations
- Inserm (FR)
- Université Paris-Est Créteil (FR)
- 1Institut National de la Santé et de la Recherche Médicale, Unité 841, Institut Mondor de Recherche Biomédicale, “Cell Interactions in the Neuromuscular System” Team, Université Paris 12 Val-de-Marne, 94000 Créteil, France
- Vrije Universiteit Amsterdam (NL)
- Assistance Publique – Hôpitaux de Paris (FR)
- Venue
- The Journal of Experimental Medicine
- Publisher
- Rockefeller University Press
- Published
- 2007-05-07
- Volume
- 204
- Issue
- 5
- Pages
- 1057-1069
- ISSN
- 0022-1007 (ISSN-L)
- 1540-9538
- PMC
- PMC2118577
- OpenAlex
- W2108723188
- Cited by
- 2,002
- References
- 82
- Citations by year
- 2026: 87 · 2025: 83 · 2024: 100 · 2023: 119 · 2022: 124 · 2021: 151 · 2020: 144 · 2019: 134 · 2018: 131 · 2017: 147 · 2016: 119 · 2015: 127 · 2014: 120 · 2013: 101 · 2012: 89
- FWCI
- 20.15
- Type
- journal article
- Language
- en
- Open access
- green
- europepmc.org
- Licence
- cc-by-nc-sa
- Locations
- The Journal of Experimental Medicine (publishedVersion)
- Europe PMC (PubMed Central) (publishedVersion, cc-by-nc-sa)
- PubMed Central (publishedVersion, cc-by-nc-sa)
- PubMed (publishedVersion)
- HAL (submittedVersion, other-oa)
- Funders
- Institut National de la Santé et de la Recherche Médicale
- Topics
- Life Sciences › Biochemistry, Genetics and Molecular Biology › Molecular Biology › Muscle Physiology and Disorders
- Health Sciences › Medicine › Surgery › Wound Healing and Treatments
- Life Sciences › Immunology and Microbiology › Immunology › Immune cells in cancer
- Keywords
- inflammatory monocytes, macrophage polarization, skeletal muscle regeneration, myogenesis, CX3CR1, Ly6C, F4/80, TGF-β1, myotube formation, monocyte depletion, muscle damage
- MeSH terms
- CX3C Chemokine Receptor 1, Animals, Cell Differentiation, Humans, Immunohistochemistry, Macrophages, Mice, Mutant Strains, Microspheres, Monocytes, Phagocytosis, DNA Primers, Muscle, Skeletal, Receptors, Chemokine, Reverse Transcriptase Polymerase Chain Reaction, Muscle Development, CD11b Antigen, Green Fluorescent Proteins, Mice
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review
