Depressive Symptoms and Other Psychosocial Factors as Predictors of Stroke in the Elderly
Abstract
The aim of this paper is to assess the influence of selected psychosocial factors as predictors of stroke incidence in a probability sample of noninstitutionalized elderly. The main psychosocial factor of interest was depression. Marital status, social support, social networks, and religiousness were also assessed as potential antecedent or mediating factors. The data were obtained from a prospective longitudinal study based on 2,812 individuals aged 65 years and over living in New Haven, Connecticut. The incidence of stroke was monitored from the baseline interview in 1982 until December 1988. Depression, measured by the Center for Epidemiologic Studies Depression Scale (CES-D), was measured at baseline as were other predictor variables. Univariate Cox regression analyses revealed that higher CES-D scores were predictive of greater stroke incidence (p < 0.05). More frequent attendance at religious services was associated with lower incidence (p < 0.001). CES-D scores were also correlated with many measures of sociodemographic, health, and physical function factors in our multivariate analysis (p < 0.05). When combined with other significant predictor variables such as age, sex, hypertension, diabetes, physical function, and smoking, neither depression nor religious attendance retained its significance.
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Two lower quality studies and five well-done studies (13%, including one at a trend level) reported higher BP in the more R/S or with religious fasting.
“Two lower quality studies [405, 406] and five well-done studies [407–411] (13%, including one at a trend level), however, reported higher BP in the more R/S or with religious fasting.”
From Religion, Spirituality, and Health: The Research and Clinical Implications (2012) · cites this paper as [406]
Colantonio et al. (1992) did not find significant associations between organizational religiosity and risk of stroke among older non-institutionalized individuals.
“Colantonio et al. (1992) did not find significant associations between organizational religiosity and risk of stroke among older non-institutionalized individuals.”
From Advancing our understanding of religion and spirituality in the context of behavioral medicine (2017) · cites this paper as Colantonio et al., 1992
Cites
The CES-D Scale: A Self-Report Depression Scale for Research in the General Population
Radloff, L. S. (1977) · Applied Psychological Measurement · doi:10.1177/014662167700100306 · Cited by 53,267 · see citing works
Social Relationships and Health
House, J. S., Landis, K. R., & Umberson, D. (1988) · Science · doi:10.1126/science.3399889 · Cited by 7,073 · see citing works
BERKMAN, L. F., & SYME, S. L. (1979) · American Journal of Epidemiology · doi:10.1093/oxfordjournals.aje.a112674 · Cited by 5,341 · see citing works
Pfeiffer, E. A. (1975) · Journal of the American Geriatrics Society · doi:10.1111/j.1532-5415.1975.tb00927.x · Cited by 5,320 · see citing works
The Functioning and Well-being of Depressed Patients: Results From the Medical Outcomes Study
Wells, K. B. (1989) · JAMA · doi:10.1001/jama.1989.03430070062031 · Cited by 2,130 · see citing works
Bioenergetic studies in adult patients recovering from semi-starvation.
Heymsfield, S., McManus, C., Hill, J., Digirolamo, M., Nixon, D., Head, A., & Grossman, G. (1985) · PubMed · Cited by 1,410 · see citing works
Caregivers of the Frail Elderly: A National Profile
Stone, R., Cafferata, G. L., & Sangl, J. A. (1987) · The Gerontologist · doi:10.1093/geront/27.5.616 · Cited by 1,216 · see citing works
A Guttman Health Scale for the Aged
Rosow, I., & Breslau, N. (1966) · Journal of Gerontology · doi:10.1093/geronj/21.4.556 · Cited by 1,132 · see citing works
Meta-analysis of relation between cigarette smoking and stroke.
Shinton, R., & Beevers, G. (1989) · British medical journal · doi:10.1136/bmj.298.6676.789 · Cited by 1,131 · see citing works
THE EPIDEMIOLOGIC EVIDENCE FOR A RELATIONSHIP BETWEEN SOCIAL SUPPORT AND HEALTH
Broadhead, W. E., Kaplan, B. H., James, S. A., Wagner, E. H., Schoenbach, V. J., GRIMSON, R. C., Heyden, S., Tibblin, G., & Gehlbach, S. H. (1983) · American Journal of Epidemiology · doi:10.1093/oxfordjournals.aje.a113575 · Cited by 917 · see citing works
DEPRESSIVE SYMPTOMS IN RELATION TO PHYSICAL HEALTH AND FUNCTIONING IN THE ELDERLY
Berkman, L. F., Berkman, C., Kasl, S. V., FREEMAN, D. H., Leo-Summers, L. S., Ostfeld, A. M., Cornoni‐Huntley, J. C., & Brody, J. A. (1986) · American Journal of Epidemiology · doi:10.1093/oxfordjournals.aje.a114408 · Cited by 812 · see citing works
Self-citationEpidemiology of dysphoria and depression in an elderly population
Blazer, D. G., & Williams, C. (1980) · American Journal of Psychiatry · doi:10.1176/ajp.137.4.439 · Cited by 638 · see citing works
Religious Involvement and the Health of the Elderly: Some Hypotheses and an Initial Test
Idler, E. L. (1987) · Social Forces · doi:10.1093/sf/66.1.226 · Cited by 486 · see citing works
Depression in the medically ill: an overview
Rodin, G., & Voshart, K. (1986) · American Journal of Psychiatry · doi:10.1176/ajp.143.6.696 · Cited by 440 · see citing works
The Framingham Disability Study: II. Physical disability among the aging.
Jette, A. M., & Branch, L. G. (1981) · American Journal of Public Health · doi:10.2105/ajph.71.11.1211 · Cited by 393 · see citing works
Wade, D. T., Legh-Smith, J., & Hewer, R. A. (1987) · The British Journal of Psychiatry · doi:10.1192/bjp.151.2.200 · Cited by 288 · see citing works
PSYCHOSOCIAL PREDICTORS OF MORTALITY AMONG THE ELDERLY POOR
Zuckerman, D. M., Kasl, S. V., & Ostfeld, A. M. (1984) · American Journal of Epidemiology · doi:10.1093/oxfordjournals.aje.a113759 · Cited by 285 · see citing works
Self-citationPsychiatric disorders and 15-month mortality in a community sample of older adults.
BRUCE, M. L., & Leaf, P. J. (1989) · American Journal of Public Health · doi:10.2105/ajph.79.6.727 · Cited by 259 · see citing works
Increased Mortality Rates in Late-life Depression
Murphy, E., Smith, R., Lindesay, J. E. B., & Slattery, J. (1988) · The British Journal of Psychiatry · doi:10.1192/bjp.152.3.347 · Cited by 244 · see citing works
Moritz, D. J., Kasl, S. V., & Berkman, L. F. (1989) · Journal of Gerontology · doi:10.1093/geronj/44.1.s17 · Cited by 160 · see citing works
Self-citationFunctional Status and Cognitive Impairment in Alzheimer's Patients With and Without Depression
Pearson, J. L., Teri, L. L., Reifler, B. V., & Raskind, M. A. (1989) · Journal of the American Geriatrics Society · doi:10.1111/j.1532-5415.1989.tb06674.x · Cited by 142 · see citing works
A REVIEW OF STROKE EPIDEMIOLOGY
Ostfeld, A. M. (1980) · Epidemiologic Reviews · doi:10.1093/oxfordjournals.epirev.a036219 · Cited by 104 · see citing works
Self-citationHigh fatality rates of late-life depression associated with cardiovascular disease
Rabins, P. V., Harvis, K. A., & Koven, S. J. (1985) · Journal of Affective Disorders · doi:10.1016/0165-0327(85)90096-5 · Cited by 96 · see citing works
Aging in the Eighties: Functional Limitations of Individuals Age 65 Years and Over
Dawson, D. A., Hendershot, G. E., & Fulton, J. P. (1987) · PsycEXTRA Dataset · doi:10.1037/e605432007-001 · Cited by 81 · see citing works
Mustacchi, P. O. (1985) · Europe PMC (PubMed Central) · Cited by 80 · see citing works
Depression, Dementia and Disability in the Elderly
Griffiths, R. A., Good, W. R., Watson, N., O'Donnell, H. F., Fell, P. J., & Shakespeare, J. (1987) · The British Journal of Psychiatry · doi:10.1192/bjp.150.4.482 · Cited by 78 · see citing works
An overview of the epidemiology of stroke.
Pa, W. (1990) · PubMed · Cited by 66 · see citing works
Gender and ethnic differences in the health practices of the elderly poor
Lubben, J. E., Weiler, P. G., & Chi, I. (1989) · Journal of Clinical Epidemiology · doi:10.1016/0895-4356(89)90068-1 · Cited by 25 · see citing works
EPIDEMIOLOGY OF STROKE, 1980–1990: A PROGRESS REPORT
Ostfeld, A. M., & WILK, E. (1990) · Epidemiologic Reviews · doi:10.1093/oxfordjournals.epirev.a036059 · Cited by 24 · see citing works
Self-citation
Flagged first, then by citations
Cited by
Sorted by citations
Religion, Spirituality, and Health: The Research and Clinical Implications
Koenig, H. G. (2012) · ISRN Psychiatry · doi:10.5402/2012/278730 · Cited by 2,423 · see citing works
“We located nine studies that examined this relationship, of which four reported a lower risk of stroke, all having quality ratings of seven or higher [414–417].”
BackgroundValtorta, N. K., Kanaan, M., Gilbody, S., Ronzi, S., & Hanratty, B. (2016) · Heart · doi:10.1136/heartjnl-2015-308790 · Cited by 1,971 · see citing works
Religion and spirituality: Linkages to physical health.
Powell, L. H., Shahabi, L., & Thoresen, C. E. (2003) · American Psychologist · doi:10.1037/0003-066x.58.1.36 · Cited by 1,093 · see citing works
Depression and the risk for cardiovascular diseases: Systematic review and meta analysis
Van der Kooy, K., van Hout, H., Marwijk, H., Marten, H., Stehouwer, C., & Beekman, A. (2007) · International Journal of Geriatric Psychiatry · doi:10.1002/gps.1723 · Cited by 951 · see citing works
Health Promoting Effects of Friends and Family on Health Outcomes in Older Adults
Seeman, T. E. (2000) · American Journal of Health Promotion · doi:10.4278/0890-1171-14.6.362 · Cited by 634 · see citing works
Does Religious Attendance Prolong Survival? A Six-Year Follow-Up Study of 3,968 Older Adults
Koenig, H. G., Hays, J. C., Larson, D. B., George, L. K., Cohen, H. J., McCullough, M. E., Meador, K. G., & Blazer, D. G. (1999) · The Journals of Gerontology Series A: Biological Sciences and Medical Sciences · doi:10.1093/gerona/54.7.m370 · Cited by 341 · see citing works
Koenig, H. G., Cohen, H. J., George, L. K., Hays, J. C., Larson, D. B., & Blazer, D. G. (1997) · The International Journal of Psychiatry in Medicine · doi:10.2190/40nf-q9y2-0gg7-4wh6 · Cited by 251 · see citing works
Religious Participation, Interleukin-6, and Mortality in Older Adults.
Lutgendorf, S. K., Russell, D., Ullrich, P., Harris, T. B., & Wallace, R. (2004) · Health Psychology · doi:10.1037/0278-6133.23.5.465 · Cited by 184 · see citing works
Prospective study of depressive symptoms and risk of stroke among Japanese
Ohira, T., Iso, H., Satoh, S., Sankai, T., Tanigawa, T., Ogawa, Y., Imano, H., Sato, S., Kitamura, A., & Shimamoto, T. (2001) · Stroke · doi:10.1161/01.str.32.4.903 · Cited by 153 · see citing works
Schnall, E., Wassertheil-Smoller, S., Swencionis, C., Zemon, V., Tinker, L., O'Sullivan, M. J., Van Horn, L., & Goodwin, M. (2010) · Psychology & Health · doi:10.1080/08870440802311322 · Cited by 139 · see citing works
Religious Service Attendance and Allostatic Load Among High-Functioning Elderly
Maselko, J., Kubzansky, L., Kawachi, I., Seeman, T., & Berkman, L. (2007) · Psychosomatic Medicine · doi:10.1097/psy.0b013e31806c7c57 · Cited by 124 · see citing works
Advancing our understanding of religion and spirituality in the context of behavioral medicine
Park, C. L., Masters, K. S., Salsman, J. M., Wachholtz, A., Clements, A. D., Salmoirago-Blotcher, E., Trevino, K., & Wischenka, D. M. (2017) · Journal of Behavioral Medicine · doi:10.1007/s10865-016-9755-5 · Cited by 119 · see citing works
The Relationship between Attendance at Religious Services and Cardiovascular Inflammatory Markers
King, D. E., Mainous, A. G., Steyer, T. E., & Pearson, W. (2001) · The International Journal of Psychiatry in Medicine · doi:10.2190/f4mp-klye-ved4-3ldd · Cited by 87 · see citing works
Attendance at Religious Services and Physical Functioning After Stroke Among Older Mexican Americans
Berges, I.-M., Kuo, Y.-F., Markides, K. S., & Ottenbacher, K. (2007) · Experimental Aging Research · doi:10.1080/03610730601005893 · Cited by 82 · see citing works
Involvement of IL-1β in acute stress-induced worsening of cerebral ischaemia in rats
Caso, J. R., Moro, M. A., Lorenzo, P., Lizasoain, I., & Leza, J. C. (2007) · European Neuropsychopharmacology · doi:10.1016/j.euroneuro.2007.02.009 · Cited by 84 · see citing works
Relationship with God and the Quality of Life of Prostate Cancer Survivors
Gall, T. L. (2004) · Quality of Life Research · doi:10.1023/b:qure.0000040789.49691.59 · Cited by 73 · see citing works
Burazeri, G., Goda, A., & Kark, J. D. (2008) · Annals of Epidemiology · doi:10.1016/j.annepidem.2008.09.001 · Cited by 65 · see citing works
The role of tumor necrosis factor-alpha in stress-induced worsening of cerebral ischemia in rats
Caso, J. R., Lizasoain, I., Lorenzo, P., Moro, M. A., & Leza, J. C. (2006) · Neuroscience · doi:10.1016/j.neuroscience.2006.06.009 · Cited by 45 · see citing works
- Authors
- Colantonio, A., Kasl, S. V., & Ostfeld, A. M.
- Affiliations
- University of Pittsburgh (US)
- Yale University (US)
- Corresponding author
- Colantonio, A.
- ORCID
- Colantonio, A.
- Venue
- American Journal of Epidemiology
- Publisher
- Oxford University Press (OUP)
- Published
- 1992-10-01
- Volume
- 136
- Issue
- 7
- Pages
- 884-894
- ISSN
- 0002-9262 (ISSN-L)
- 1476-6256
- OpenAlex
- W2149180041
- Cited by
- 194
- References
- 29
- Citations by year
- 2025: 4 · 2023: 44 · 2022: 4 · 2021: 2 · 2020: 1 · 2019: 2 · 2018: 1 · 2017: 2 · 2016: 2 · 2015: 2 · 2014: 4 · 2013: 5 · 2012: 9
- FWCI
- 1.47
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- American Journal of Epidemiology (publishedVersion)
- PubMed (publishedVersion)
- Funders
- National Institutes of Health (n01ag002105-019)
- National Institute on Aging (N01AG02105, AG00181)
- Topics
- Health Sciences › Medicine › Cardiology and Cardiovascular Medicine › Cardiac Health and Mental Health
- Social Sciences › Health › Health disparities and outcomes
- Health Sciences › Medicine › Public Health, Environmental and Occupational Health › Aging, Health, and Disability
- Keywords
- depression, stroke incidence, older adults, psychosocial factors, social support, social networks, marital status, religious service attendance, religiosity, stroke risk factors, physical function, hypertension, diabetes mellitus, smoking
- MeSH terms
- Aged, Aged, 80 and over, Cerebrovascular Disorders, Connecticut, Depression, Female, Humans, Male, Prognosis, Prospective Studies, Regression Analysis, Religion, Social Support, Incidence, Multivariate Analysis, Proportional Hazards Models
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