Stimulus Repetition Probability Does Not Affect Repetition Suppression in Macaque Inferior Temporal Cortex
Abstract
Recent human functional magnetic resonance imaging studies (Summerfield C, Trittschuh EH, Monti JM, Mesulam MM, Egner T. 2008. Neural repetition suppression reflects fulfilled perceptual expectations. Nat Neurosci. 11:1004-1006.) showed that adaptation or repetition suppression is affected by contextual factors related to perceptual expectations, suggesting that adaptation results from a fulfillment of perceptual expectation or a reduction in prediction error. This view contrasts with the bottom-up fatigue or sharpening mechanisms of adaptation proposed in single-cell studies. We examined whether stimulus repetition probability affects adaptation of spiking activity and local field potentials (LFPs) in macaque inferior temporal (IT) cortex, using a protocol similar to that of Summerfield et al. Monkeys were exposed to 2 randomly interleaved trials, each consisting of either 2 identical (rep trial) or 2 different stimuli (alt trial). Trials were presented in repetition (rep) blocks consisting of 75% of rep trials and 25% of alt trials or in alternation (alt) blocks having opposite repetition probabilities. For both spiking and LFP activities, the stimulus-selective adaptation did not differ significantly between rep and alt blocks. The number of preceding rep or alt trials and the trial position within a block did not affect adaptation. This absence of any effect of stimulus repetition probability on adaptation suggests that adaptation in IT is not caused by contextual factors related to perceptual expectation.
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Kaliukhovich and Vogels reported responses to deviant stimuli indistinguishable from responses to infrequent but conditionally probable stimuli.
“Attempting to replicate the findings of Summerfield et al. 57 with single‐cell recordings in macaque IT, Kaliukhovich and Vogels 71 reported that responses to deviant stimuli were indistinguishable from responses to infrequent, but conditionally probable, stimuli.”
From Evaluating the neurophysiological evidence for predictive processing as a model of perception (2020) · cites this paper as [71]
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- Authors
- Kaliukhovich, D. A., & Vogels, R.
- Affiliations
- KU Leuven (BE)
- Venue
- Cerebral Cortex
- Publisher
- Oxford University Press (OUP)
- Published
- 2010-11-22
- Volume
- 21
- Issue
- 7
- Pages
- 1547-1558
- ISSN
- 1047-3211 (ISSN-L)
- 1460-2199
- OpenAlex
- W2117129339
- Cited by
- 131
- References
- 45
- Citations by year
- 2026: 2 · 2025: 5 · 2024: 7 · 2023: 8 · 2022: 6 · 2021: 6 · 2020: 7 · 2019: 3 · 2018: 12 · 2017: 10 · 2016: 14 · 2015: 8 · 2014: 11 · 2013: 11 · 2012: 12
- FWCI
- 6.00
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- Cerebral Cortex (publishedVersion)
- PubMed (publishedVersion)
- Lirias (submittedVersion)
- Topics
- Life Sciences › Neuroscience › Cognitive Neuroscience › Visual perception and processing mechanisms
- Life Sciences › Neuroscience › Cognitive Neuroscience › Face Recognition and Perception
- Life Sciences › Neuroscience › Cognitive Neuroscience › Memory and Neural Mechanisms
- Keywords
- repetition suppression, neural adaptation, inferior temporal cortex, perceptual expectations, prediction error, local field potentials, spiking activity, macaque
- MeSH terms
- Action Potentials, Adaptation, Physiological, Animals, Female, Macaca, Macaca mulatta, Male, Neural Inhibition, Photic Stimulation, Random Allocation, Temporal Lobe
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