The Effects of Visual Stimulation and Selective Visual Attention on Rhythmic Neuronal Synchronization in Macaque Area V4
Open accessAbstract
Selective attention lends relevant sensory input priority access to higher-level brain areas and ultimately to behavior. Recent studies have suggested that those neurons in visual areas that are activated by an attended stimulus engage in enhanced gamma-band (30–70 Hz) synchronization compared with neurons activated by a distracter. Such precise synchronization could enhance the postsynaptic impact of cells carrying behaviorally relevant information. Previous studies have used the local field potential (LFP) power spectrum or spike-LFP coherence (SFC) to indirectly estimate spike synchronization. Here, we directly demonstrate zero-phase gamma-band coherence among spike trains of V4 neurons. This synchronization was particularly evident during visual stimulation and enhanced by selective attention, thus confirming the pattern inferred from LFP power and SFC. We therefore investigated the time course of LFP gamma-band power and found rapid dynamics consistent with interactions of top-down spatial and feature attention with bottom-up saliency. In addition to the modulation of synchronization during visual stimulation, selective attention significantly changed the prestimulus pattern of synchronization. Attention inside the receptive field of the recorded neuronal population enhanced gamma-band synchronization and strongly reduced α-band (9–11 Hz) synchronization in the prestimulus period. These results lend further support for a functional role of rhythmic neuronal synchronization in attentional stimulus selection.
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The encoding of salience or precision can also be understood in terms of synchronous gain and fast oscillatory dynamics associated with binding, attention and dynamic coordination.
“As noted above, the encoding of salience or precision can also be understood in terms of synchronous gain [30] and fast (oscillatory) dynamics associated with binding, attention and dynamic coordination [4,5].”
From Cerebral hierarchies: predictive processing, precision and the pulvinar (2015) · cites this paper as [5]
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“Fries et al. (2001, 2008) found that gamma synchronization in area V4 was stronger when attention was directed to a stimulus inside the RF.”
BackgroundCortical layers, rhythms and BOLD signals
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- Authors
- Fries, P., Womelsdorf, T., Oostenveld, R., & Desimone, R.
- Affiliations
- Radboud University Nijmegen (NL)
- McGovern Institute for Brain Research (US)
- National Institutes of Health (US)
- Corresponding author
- Fries, Pascal
- Venue
- The Journal of Neuroscience
- Publisher
- Society for Neuroscience
- Published
- 2008-04-30
- Volume
- 28
- Issue
- 18
- Pages
- 4823-4835
- ISSN
- 0270-6474 (ISSN-L)
- 1529-2401
- PMC
- PMC3844818
- OpenAlex
- W2160996295
- Cited by
- 458
- References
- 40
- Citations by year
- 2026: 3 · 2025: 9 · 2024: 43 · 2023: 20 · 2022: 12 · 2021: 19 · 2020: 35 · 2019: 14 · 2018: 23 · 2017: 31 · 2016: 26 · 2015: 32 · 2014: 36 · 2013: 35 · 2012: 27
- FWCI
- 15.85
- Type
- journal article
- Language
- en
- Open access
- hybrid
- doi.org
- Licence
- Locations
- Journal of Neuroscience (publishedVersion, cc-by-nc-sa)
- Europe PMC (PubMed Central) (publishedVersion)
- PubMed Central (publishedVersion)
- PubMed (publishedVersion)
- Radboud Repository (Radboud University) (submittedVersion, other-oa)
- Radboud Repository (Radboud University) (submittedVersion)
- Funders
- European Science Foundation
- Volkswagen Foundation (I/79876)
- Nederlandse Organisatie voor Wetenschappelijk Onderzoek (452-03-344)
- National Institutes of Health
- National Institute of Mental Health
- National Eye Institute (R01EY017292)
- Topics
- Life Sciences › Neuroscience › Cognitive Neuroscience › Neural dynamics and brain function
- Life Sciences › Neuroscience › Cognitive Neuroscience › Visual perception and processing mechanisms
- Social Sciences › Psychology › Experimental and Cognitive Psychology › Multisensory perception and integration
- Keywords
- visual selective attention, gamma-band synchronization, neuronal synchronization, area V4, macaque visual cortex, spike trains, local field potentials, top-down attention, bottom-up saliency, receptive fields
- MeSH terms
- Animals, Attention, Color Perception, Cortical Synchronization, Evoked Potentials, Visual, Fourier Analysis, Macaca mulatta, Male, Neurons, Photic Stimulation, Psychophysics, Time Factors, Visual Cortex
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