A pure salience response in posterior parietal cortex
Open accessAbstract
When exploring a visual scene, some objects perceptually popout because of a difference of color, shape, or size. This bottom-up information is an important part of many models describing the allocation of visual attention. It has been hypothesized that the lateral intraparietal area (LIP) acts as a "priority map," integrating bottom-up and top-down information to guide the allocation of attention. Despite a large literature describing top-down influences in LIP, the presence of a pure salience response to a salient stimulus defined by its static features alone has not been reported. We compared LIP responses with colored salient stimuli and distractors in a passive fixation task. Many LIP neurons responded preferentially to 1 of the 2 colored stimuli, yet the mean responses to the salient stimuli were significantly higher than to distractors, independent of the features of the stimuli. These enhanced responses were significant within 75 ms, and the mean responses to salient and distractor stimuli were tightly correlated, suggesting a simple gain control. We propose that a pure salience signal rapidly appears in LIP by collating salience signals from earlier visual areas. This contributes to the creation of a priority map, which is used to guide attention and saccades.
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Exogenous and endogenous attention mechanisms are combined in LIP, SC, and FEF to generate a saliency map.
“It has been proposed that exogenous and endogenous attention mechanisms are combined in area LIP [34], the SC [35], and the FEF (e.g. [31]) to generate a saliency map [34].”
From Linking ADHD to the Neural Circuitry of Attention (2017) · cites this paper as [34]
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- Authors
- Arcizet, F., Mirpour, K., & Bisley, J. W.
- Affiliations
- University of California, Los Angeles (US)
- Venue
- Cerebral Cortex
- Publisher
- Oxford University Press (OUP)
- Published
- 2011-03-21
- Volume
- 21
- Issue
- 11
- Pages
- 2498-2506
- ISSN
- 1047-3211 (ISSN-L)
- 1460-2199
- PMC
- PMC3218666
- OpenAlex
- W2127341559
- Cited by
- 90
- References
- 58
- Citations by year
- 2026: 2 · 2025: 3 · 2023: 3 · 2022: 4 · 2021: 5 · 2020: 7 · 2019: 4 · 2018: 1 · 2017: 9 · 2016: 8 · 2015: 5 · 2014: 14 · 2013: 9 · 2012: 12
- FWCI
- 6.34
- Type
- journal article
- Language
- en
- Open access
- green
- www.ncbi.nlm.nih.gov
- Locations
- Cerebral Cortex (publishedVersion)
- PubMed Central (publishedVersion)
- PubMed (publishedVersion)
- Funders
- National Eye Institute (R01EY019273)
- Topics
- Life Sciences › Neuroscience › Cognitive Neuroscience › Visual perception and processing mechanisms
- Physical Sciences › Computer Science › Computer Vision and Pattern Recognition › Visual Attention and Saliency Detection
- Life Sciences › Neuroscience › Cognitive Neuroscience › Neural and Behavioral Psychology Studies
- Keywords
- salience, lateral intraparietal area, posterior parietal cortex, visual attention, priority map, bottom-up attention, top-down attention, gain control, saccades
- MeSH terms
- Animals, Attention, Macaca mulatta, Male, Parietal Lobe, Photic Stimulation, Saccades, Visual Perception, Patch-Clamp Techniques
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