Physical activity and cancer prevention–data from epidemiologic studies
Abstract
PURPOSE: The aim of this paper is to examine whether physical activity plays any role in the prevention of cancer. METHODS: To accomplish this, data from published epidemiologic studies on the relation between physical activity and the risk of developing cancer were reviewed. RESULTS: The data are clear in showing that physically active men and women have about a 30-40% reduction in the risk of developing colon cancer, compared with inactive persons. Although the data are sparse, it appears that 30-60 min.d(-1) of moderate- to vigorous-intensity physical activity is needed to decrease risk. There is a dose-response relation, with risk declining further at higher levels of physical activity. It is also clear that physical activity is not associated with the risk of developing rectal cancer. With regard to breast cancer, there is reasonably clear evidence that physically active women have about a 20-30% reduction in risk, compared with inactive women. It also appears that 30-60 min.d(-1) of moderate- to vigorous-intensity physical activity is needed to decrease the risk of breast cancer, and that there is likely a dose-response relation. For prostate cancer, the data are inconsistent regarding whether physical activity plays any role in the prevention of this cancer. There are relatively few studies on physical activity and lung cancer prevention. The available data suggest that physically active individuals have a lower risk of lung cancer; however, it is difficult to completely account for cigarette smoking. There is little information on the role of physical activity in preventing other cancers. CONCLUSION: Physical activity is associated with lower risk of developing certain site-specific cancers, in particular colon and breast cancers.
Integrity signals
Registry
Cites
Statistics
Claims the paper makes
Claims other papers make about this one
Each is checked against this paper’s own text: does it say what the citing paper says it does?
Observational studies suggest that exercise plays an important role in preventing cardiovascular disease and cancer, the two major causes of death among older adults.
“Observational studies suggest that exercise plays an important role in preventing cardiovascular disease and cancer,30 31 the two major causes of death among older adults.”
From Effect of exercise training for five years on all cause mortality in older adults—the Generation 100 study: randomised controlled trial (2020) · cites this paper as [31]
Evidence from observational epidemiologic studies consistently shows that higher levels of physical activity are associated with a lower risk of colon, postmenopausal breast, and endometrial cancer.
“Evidence from observational epidemiologic studies consistently shows that higher levels of physical activity are associated with a lower risk of colon, postmenopausal breast, and endometrial cancer (17,36,37).”
From Diabetes and Cancer (2010) · cites this paper as [36]
Cites
Jemal, A., Thomas, A., Murray, T., & Thun, M. J. (2002) · CA A Cancer Journal for Clinicians · doi:10.3322/canjclin.52.1.23 · Cited by 2,916 · see citing works
Kushi, L. H., Byers, T., Doyle, C., Bandera, E. V., McCullough, M., Gansler, T., Andrews, K. S., Thun, M. J., & The American Cancer Society 2006 Nutrition and Physical Activity Guidelines Advisory Committee (2006) · CA A Cancer Journal for Clinicians · doi:10.3322/canjclin.56.5.254 · Cited by 1,901 · see citing works
Physical Activity and Cardiovascular Health
(1996) · JAMA · doi:10.1001/jama.276.3.241 · Cited by 1,001 · see citing works
Physical Activity, Obesity, Height, and the Risk of Pancreatic Cancer
Michaud, D. S. (2001) · JAMA · doi:10.1001/jama.286.8.921 · Cited by 663 · see citing works
Physical activity and the risk of breast cancer
Thune, I., Brenn, T., Lund, E., & Gaard, M. (1997) · New England Journal of Medicine · doi:10.1056/nejm199705013361801 · Cited by 569 · see citing works
Leisure-Time Physical Activity, Body Size, and Colon Cancer in Women
Martinez, M. E., Giovannucci, E., Spiegelman, D., Willett, W. C., Hunter, D. J., & Colditz, G. A. (1997) · JNCI Journal of the National Cancer Institute · doi:10.1093/jnci/89.13.948 · Cited by 419 · see citing works
Byers, T., Nestle, M., McTiernan, A., Doyle, C., Currie-Williams, A., Gansler, T., & Thun, M. (2002) · CA: A Cancer Journal for Clinicians · doi:10.3322/canjclin.52.2.92 · Cited by 336 · see citing works
Physical Activity and Risk of Developing Colorectal Cancer Among College Alumni
Lee, I.-M., Paffenbarger, R. S., & Hsieh, C. (1991) · JNCI Journal of the National Cancer Institute · doi:10.1093/jnci/83.18.1324 · Cited by 290 · see citing works
A prospective study of recreational physical activity and breast cancer risk.
Rockhill, B., Willett, W., Hunter, D. J., Manson, J., Hankinson, S., & Colditz, G. (1999) · Archives of Internal Medicine · doi:10.1001/archinte.159.19.2290 · Cited by 234 · see citing works
Reducing the risk of cancer with healthy food choices and physical activity
Byers, T. (2002) · CA A Cancer Journal for Clinicians · Cited by 161 · see citing works
Physical activity and risk of lung cancer
Lee, I.-M. M., Sesso, H. D., & Paffenbarger, R. S. (1999) · International Journal of Epidemiology · doi:10.1093/ije/28.4.620 · Cited by 146 · see citing works
Physical activity and colon cancer: A public health perspective
Slattery, M. L., Edwards, S. L., Ma, K., FRIEDMAN, G. D., & Potter, J. D. (1997) · Annals of Epidemiology · doi:10.1016/s1047-2797(96)00129-9 · Cited by 136 · see citing works
Physical Activity and Risk of Prostatic Cancer among College Alumni
Lee, I., Paffenbarger, R. S., & Hsieh, C. (1992) · American Journal of Epidemiology · doi:10.1093/oxfordjournals.aje.a116269 · Cited by 123 · see citing works
Photobleaching of protoporphyrin IX in cells incubated with 5-aminolevulinic acid
Moan, J. E., Streckytė, G., Bagdonas, S., Gadmar, Ø. B., & Berg, K. (1997) · International Journal of Cancer · doi:10.1002/(sici)1097-0215(19970106)70:1 · Cited by 118 · see citing works
A prospective study of physical activity and prostate cancer in male health professionals.
Giovannucci, E. L., Leitzmann, M. F., Spiegelman, D. L., Rimm, E. B., Colditz, G. A., Stampfer, M. J., & Willett, W. C. (1998) · PubMed · Cited by 95 · see citing works
Lee, I.-M. M., Sesso, H. D., & Paffenbarger, R. S. (2001) · Cancer Causes & Control · doi:10.1023/a:1008952528771 · Cited by 94 · see citing works
Physical activity and breast cancer risk: the Women's Health Study (United States)
Lee, I.-M. M., Rexrode, K. M., Cook, N. R., Hennekens, C. H., & Buring, J. E. (2001) · Cancer Causes & Control · doi:10.1023/a:1008948125076 · Cited by 88 · see citing works
Physical activity, body weight, and pancreatic cancer mortality
Lee, I.-M. M., Sesso, H. D., Oguma, Y., & Paffenbarger, R. S. (2003) · British Journal of Cancer · doi:10.1038/sj.bjc.6600782 · Cited by 73 · see citing works
Does Physical Activity Play a Role in the Prevention of Prostate Cancer?
Lee, I.-M. M., Sesso, H. D., Chen, J. J., & Paffenbarger, R. S. (2001) · Epidemiologic Reviews · doi:10.1093/oxfordjournals.epirev.a000778 · Cited by 56 · see citing works
The Relation of Muscular Activity to Carcinoma: A Preliminary Report
Sivertsen, I., & Dahlstrom, A. W. (1921) · The Journal of Cancer Research · doi:10.1158/jcr.1921.365 · Cited by 38 · see citing works
Cherry, T. (1922) · The Medical Journal of Australia · doi:10.5694/j.1326-5377.1922.tb118373.x · Cited by 18 · see citing works
Flagged first, then by citations
2 of the 24 references couldn’t be matched to a known paper.
Cited by
Sorted by citations
Health benefits of physical activity: the evidence
Warburton, D. E. R. (2006) · Canadian Medical Association Journal · doi:10.1503/cmaj.051351 · Cited by 8,007 · see citing works
Non-Small Cell Lung Cancer: Epidemiology, Risk Factors, Treatment, and Survivorship
Molina, J. R., Yang, P., Cassivi, S. D., Schild, S. E., & Adjei, A. A. (2008) · Mayo Clinic Proceedings · doi:10.4065/83.5.584 · Cited by 3,927 · see citing works
2023 ESC Guidelines for the management of cardiomyopathies
Arbelo, E., Protonotarios, A., Gimeno, J. R., Arbustini, E., Villa, R. B., Basso, C., Bezzina, C. R., Biagini, E., Blom, N. A., de Boer, R. A., et al. (2023) · European Heart Journal · doi:10.1093/eurheartj/ehad194 · Cited by 2,947 · see citing works
Giovannucci, E., Harlan, D. M., Archer, M. C., Bergenstal, R. M., Gapstur, S. M., Habel, L. A., Pollak, M., Regensteiner, J. G., & Yee, D. (2010) · Diabetes Care · doi:10.2337/dc10-0666 · Cited by 2,366 · see citing works
Sedentary Behavior, Exercise, and Cardiovascular Health
Lavie, C. J., Ozemek, C., Carbone, S., Katzmarzyk, P. T., & Blair, S. N. (2019) · Circulation Research · doi:10.1161/circresaha.118.312669 · Cited by 1,617 · see citing works
Hertzog, C., Kramer, A. F., Wilson, R. S., & Lindenberger, U. (2008) · Psychological Science in the Public Interest · doi:10.1111/j.1539-6053.2009.01034.x · Cited by 1,495 · see citing works
Diabetes and Cancer: A Consensus Report
Giovannucci, E. L., Harlan, D. M., Archer, M. C., Bergenstal, R. M., Gapstur, S. M., Habel, L. A., Pollak, M., Regensteiner, J. G., & Yee, D. (2010) · CA A Cancer Journal for Clinicians · doi:10.3322/caac.20078 · Cited by 1,065 · see citing works
A systematic review of the evidence for Canada's Physical Activity Guidelines for Adults
Warburton, D. E., Charlesworth, S., Ivey, A., Nettlefold, L., & Bredin, S. S. (2010) · International Journal of Behavioral Nutrition and Physical Activity · doi:10.1186/1479-5868-7-39 · Cited by 902 · see citing works
Multi-sensor fusion in body sensor networks: State-of-the-art and research challenges
Gravina, R., Alinia, P., Ghasemzadeh, H., & Fortino, G. (2017) · Information Fusion · doi:10.1016/j.inffus.2016.09.005 · Cited by 899 · see citing works
Updating the evidence that physical activity is good for health: an epidemiological review 2000–2003
Bauman, A. E. (2004) · Journal of Science and Medicine in Sport · doi:10.1016/s1440-2440(04)80273-1 · Cited by 768 · see citing works
Exercise, brain, and cognition across the life span.
Voss, M. W., Nagamatsu, L. S., Liu-Ambrose, T., & Kramer, A. F. (2011) · Journal of Applied Physiology · doi:10.1152/japplphysiol.00210.2011 · Cited by 601 · see citing works
Effects of exercise and diet on chronic disease
Roberts, C. K., & Barnard, R. J. (2005) · Journal of Applied Physiology · doi:10.1152/japplphysiol.00852.2004 · Cited by 556 · see citing works
Health benefits of physical activity in older patients: a review
Vogel, T., Bréchat, P.-H., Leprêtre, P., Kaltenbach, G., Berthel, M., & Lonsdorfer, J. (2009) · International Journal of Clinical Practice · doi:10.1111/j.1742-1241.2008.01957.x · Cited by 540 · see citing works
The validity and reliability of a novel activity monitor as a measure of walking
Ryan, C. G., Grant, P., Tigbe, W. W., & Granat, M. H. (2006) · British Journal of Sports Medicine · doi:10.1136/bjsm.2006.027276 · Cited by 490 · see citing works
Increasing Physical Activity With Mobile Devices: A Meta-Analysis
Fanning, J., Mullen, S. P., & McAuley, E. (2012) · Journal of Medical Internet Research · doi:10.2196/jmir.2171 · Cited by 457 · see citing works
Ann, W. H. (2006) · Frontiers in bioscience · doi:10.2741/1891 · Cited by 447 · see citing works
Physical Activity Recommendations and Decreased Risk of Mortality
Leitzmann, M. F. (2007) · Archives of Internal Medicine · doi:10.1001/archinte.167.22.2453 · Cited by 437 · see citing works
AMPK, the metabolic syndrome and cancer
Luo, Z., Saha, A. K., Xiang, X., & Ruderman, N. B. (2005) · Trends in Pharmacological Sciences · doi:10.1016/j.tips.2004.12.011 · Cited by 426 · see citing works
Exercise and the heart: the good, the bad, and the ugly
Sharma, S., Merghani, A., & Mont, L. (2015) · European Heart Journal · doi:10.1093/eurheartj/ehv090 · Cited by 398 · see citing works
Benedetti, T. R. B., Antunes, P. D. C., Rodríguez-Añez, C. R., Mazo, G. Z., & Petroski, E. L. (2007) · Revista Brasileira de Medicina do Esporte · doi:10.1590/s1517-86922007000100004 · Cited by 322 · see citing works
Ning, Y., Wang, L., & Giovannucci, E. L. (2009) · Obesity Reviews · doi:10.1111/j.1467-789x.2009.00613.x · Cited by 285 · see citing works
Glynn, L. G., Hayes, P. S., Casey, M., Glynn, F., Alvarez‐Iglesias, A., Newell, J., OLaighin, G. M., Heaney, D., O'Donnell, M. J., & Murphy, A. W. (2014) · British Journal of General Practice · doi:10.3399/bjgp14x680461 · Cited by 280 · see citing works
Ginis, K. M. M., Nigg, C., & Smith, A. L. (2013) · Translational Behavioral Medicine · doi:10.1007/s13142-013-0215-2 · Cited by 223 · see citing works
Determinants of Active Leisure for Women with Young Children—an “Ethic of Care” Prevails
Miller, Y. D., & Brown, W. J. (2005) · Leisure Sciences · doi:10.1080/01490400500227308 · Cited by 257 · see citing works
Parent and child physical activity and sedentary time: Do active parents foster active children?
Jago, R., Fox, K. R., Page, A. S., Brockman, R., & Thompson, J. L. (2010) · BMC Public Health · doi:10.1186/1471-2458-10-194 · Cited by 251 · see citing works
S3-Leitlinie – Kolorektales Karzinom
Schmiegel, W., Buchberger, B., Follmann, M., Graeven, U., Heinemann, V., Langer, T. G., Nothacker, M., Porschen, R., Rödel, C. M., Rösch, T., et al. (2017) · Zeitschrift für Gastroenterologie · doi:10.1055/s-0043-121106 · Cited by 242 · see citing works
Does Physical Activity Reduce the Risk of Prostate Cancer? A Systematic Review and Meta-analysis
Liu, Y., Hu, F., Li, D., Wang, F., Zhu, L., Chen, W., Ge, J., An, R., & Zhao, Y. (2011) · European Urology · doi:10.1016/j.eururo.2011.07.007 · Cited by 231 · see citing works
Sternfeld, B., Weltzien, E. K., Quesenberry, C. P., Castillo, A., Kwan, M. L., Slattery, M. L., & Caan, B. J. (2009) · Cancer Epidemiology Biomarkers & Prevention · doi:10.1158/1055-9965.epi-08-0595 · Cited by 229 · see citing works
Metabolic reprogramming in prostate cancer
Ahmad, F., Cherukuri, M. K., & Choyke, P. L. (2021) · British Journal of Cancer · doi:10.1038/s41416-021-01435-5 · Cited by 221 · see citing works
Association between domains of physical activity and all-cause, cardiovascular and cancer mortality
Autenrieth, C. S., Baumert, J. J., Baumeister, S. E., Fischer, B., Peters, A., Döring, A., & Thorand, B. (2010) · European Journal of Epidemiology · doi:10.1007/s10654-010-9517-6 · Cited by 196 · see citing works
Chang, C., Lin, J., Wu, L., Lai, M., Chuang, L., & Chan, K. A. (2011) · Hepatology · doi:10.1002/hep.25509 · Cited by 193 · see citing works
Inoue, M., Iso, H., Yamamoto, S., Kurahashi, N., Iwasaki, M., Sasazuki, S., & Tsugane, S. (2008) · Annals of Epidemiology · doi:10.1016/j.annepidem.2008.03.008 · Cited by 188 · see citing works
S3-Leitlinie Kolorektales Karzinom Version 1.0 - Juni 2013 AWMF-Registernummer: 021/007OL
Pox, C. P., Aretz, S., Bischoff, S. C., Graeven, U., Hass, M., Heußner, P., Hohenberger, W., Holstege, A., Hübner, J., Kolligs, F. T., et al. (2013) · Zeitschrift für Gastroenterologie · doi:10.1055/s-0033-1350264 · Cited by 179 · see citing works
Validation of the International Physical Activity Questionnaire-Short Among Blacks
Wolin, K. Y., Heil, D. P., Askew, S., Matthews, C. E., & Bennett, G. G. (2008) · Journal of Physical Activity and Health · doi:10.1123/jpah.5.5.746 · Cited by 177 · see citing works
Updating the evidence on physical activity and health in women.
Brown, W., Burton, N., & Rowan, P. (2007) · American Journal of Preventive Medicine · doi:10.1016/j.amepre.2007.07.029 · Cited by 198 · see citing works
Physical activity and cancer prevention: a systematic review of clinical trials
Winzer, B., Whiteman, D. C., Reeves, M. M., & Paratz, J. D. (2011) · Cancer Causes & Control · doi:10.1007/s10552-011-9761-4 · Cited by 173 · see citing works
Bigley, A. B., Rezvani, K., Chew, C., Sekine, T., Pistillo, M., Crucian, B. E., Bollard, C. M., & Simpson, R. J. (2013) · Brain Behavior and Immunity · doi:10.1016/j.bbi.2013.10.030 · Cited by 172 · see citing works
Leisure-time physical activity and lung cancer: a meta-analysis
Tardón, A., Lee, W. J., Delgado‐Rodríguez, M., Dosemeci, M., Albanes, D., Hoover, R. N., & Blair, A. E. (2005) · Cancer Causes & Control · doi:10.1007/s10552-004-5026-9 · Cited by 170 · see citing works
Daily step goal of 10,000 steps: A literature review
Choi, B. C. K., Pak, A. W. P., Choi, J. C. L., & Choi, E. C. L. (2007) · Clinical and investigative medicine · doi:10.25011/cim.v30i3.1083 · Cited by 167 · see citing works
Téhard, B., Friedenreich, C. M., Oppert, J., & Clavel‐Chapelon, F. (2006) · Cancer Epidemiology Biomarkers & Prevention · doi:10.1158/1055-9965.epi-05-0603 · Cited by 165 · see citing works
Chen, B. P., Awasthi, R., Sweet, S. N., Minnella, E. M., Bergdahl, A., Mina, D. S., Carli, F., & Scheede‐Bergdahl, C. (2016) · Supportive Care in Cancer · doi:10.1007/s00520-016-3379-8 · Cited by 164 · see citing works
Sacker, A., & Cable, N. (2005) · European Journal of Public Health · doi:10.1093/eurpub/cki189 · Cited by 159 · see citing works
Inoue, M., Yamamoto, S., Kurahashi, N., Iwasaki, M., Sasazuki, S., & Tsugane, S. (2008) · American Journal of Epidemiology · doi:10.1093/aje/kwn146 · Cited by 160 · see citing works
Stensvold, D., Viken, H., Steinshamn, S. L., Dalen, H., Støylen, A., Loennechen, J. P., Reitlo, L. S., Zisko, N., Bækkerud, F. H., Tari, A. R., et al. (2020) · BMJ · doi:10.1136/bmj.m3485 · Cited by 154 · see citing works
Dhuli, K., Naureen, Z., Medori, M., Fioretti, F., Caruso, P., Perrone, M., Nodari, S., Manganotti, P., Xhufi, S., Bushati, M., et al. (2022) · Journal of preventive medicine and hygiene · doi:10.15167/2421-4248/jpmh2022.63.2s3.2756 · Cited by 24 · see citing works
Warburton, D. E. R., Katzmarzyk, P. T., Rhodes, R. E., & Shephard, R. J. (2007) · Applied Physiology, Nutrition, and Metabolism · doi:10.1139/h07-123 · Cited by 153 · see citing works
Physical activity, visual impairment, and eye disease
Ong, S. R., Crowston, J. G., Loprinzi, P. D., & Ramulu, P. Y. (2018) · Eye · doi:10.1038/s41433-018-0081-8 · Cited by 143 · see citing works
Almeida, O. P., Khan, K., Hankey, G. J., Yeap, B. B., Golledge, J., & Flicker, L. A. (2013) · British Journal of Sports Medicine · doi:10.1136/bjsports-2013-092814 · Cited by 137 · see citing works
Insulin resistance and cancer: epidemiological evidence
Inoue, M., & Tsugane, S. (2012) · Endocrine Related Cancer · doi:10.1530/erc-12-0142 · Cited by 137 · see citing works
A Social Identity Approach to Understanding and Promoting Physical Activity
Stevens, M. R., Rees, T., Coffee, P., Steffens, N. K., Haslam, S. A., & Polman, R. C. J. (2017) · Sports Medicine · doi:10.1007/s40279-017-0720-4 · Cited by 140 · see citing works
Exercise and Biomarkers for Cancer Prevention Studies
Campbell, K. L., & McTiernan, A. (2007) · Journal of Nutrition · doi:10.1093/jn/137.1.161s · Cited by 131 · see citing works
Nigg, C., Geller, K. S., Motl, R., Horwath, C., Wertin, K., & Dishman, R. (2011) · Psychology of Sport And Exercise · doi:10.1016/j.psychsport.2010.04.004 · Cited by 143 · see citing works
Warburton, D. E. R., Gledhill, N., Jamnik, V. K., Bredin, S. S. D., McKenzie, D. C., Stone, J., Charlesworth, S., & Shephard, R. J. (2011) · Applied Physiology, Nutrition, and Metabolism · doi:10.1139/h11-062 · Cited by 156 · see citing works
Diabetes and Cancer: Is Diabetes Causally Related to Cancer?
Suh, S., & Kim, K. (2011) · Diabetes & Metabolism Journal · doi:10.4093/dmj.2011.35.3.193 · Cited by 118 · see citing works
Physical activity levels in individuals with and without patellofemoral pain.
Glaviano, N. R., Baellow, A. L., & Saliba, S. (2017) · Physical Therapy in Sport · doi:10.1016/j.ptsp.2017.07.002 · Cited by 97 · see citing works
Solar radiation, vitamin D and survival rate of colon cancer in Norway
Moan, J. E., Porojnicu, A. C., Robsahm, T. E., Dahlback, A., Juzeniene, A., Tretli, S., & Grant, W. B. (2005) · Journal of Photochemistry and Photobiology B Biology · doi:10.1016/j.jphotobiol.2004.11.004 · Cited by 117 · see citing works
Nilsen, T. I. L., Romundstad, P., & VATTEN, L. J. (2006) · International Journal of Cancer · doi:10.1002/ijc.22184 · Cited by 116 · see citing works
Silver, J. K., & Gilchrist, L. S. (2011) · American Journal of Physical Medicine & Rehabilitation · doi:10.1097/phm.0b013e31820be4ae · Cited by 115 · see citing works
Role of Lipid Peroxidation in the Epidemiology and Prevention of Breast Cancer
Gago-Domínguez, M., Castelao, J. E., Pike, M. C., Sevanian, A., & Haile, R. W. (2005) · Cancer Epidemiology Biomarkers & Prevention · doi:10.1158/1055-9965.epi-05-0015 · Cited by 114 · see citing works
Inactivation of AMPK alters gene expression and promotes growth of prostate cancer cells
Zhou, J., Huang, W., Tao, R., Ibaragi, S., Lan, F., Ido, Y., Wu, X., Alekseyev, Y. O., Lenburg, M. E., Hu, G.-F., et al. (2009) · Oncogene · doi:10.1038/onc.2009.63 · Cited by 112 · see citing works
Health Behaviors in Cancer Survivors
Mayer, D. K., Terrin, N. C., Menon, U., Kreps, G. L., McCance, K., Parsons, S. K., & Mooney, K. H. (2007) · Oncology Nursing Forum · doi:10.1188/07.onf.643-651 · Cited by 111 · see citing works
Exercise as a Polypill for Chronic Diseases
Pareja-Galeano, H., Garatachea, N., & Lucía, A. (2015) · Progress in molecular biology and translational science · doi:10.1016/bs.pmbts.2015.07.019 · Cited by 111 · see citing works
Epidemiologic Methods in Physical Activity Studies
Lee, I. (2008) · doi:10.1093/acprof:oso/9780195183009.001.0001 · Cited by 100 · see citing works
Saqib, Z. A., Dai, J., Menhas, R., Mahmood, S., Karim, M., Sang, X., & Weng, Y. (2020) · Risk Management and Healthcare Policy · doi:10.2147/rmhp.s280339 · Cited by 105 · see citing works
Osei-Afriyie, S., Addae, A. K., Oppong, S., Amu, H., Ampofo, E., & Osei, E. (2021) · PLoS ONE · doi:10.1371/journal.pone.0253373 · Cited by 105 · see citing works
GPS-Based Exposure to Greenness and Walkability and Accelerometry-Based Physical Activity
James, P., Hart, J. E., Hipp, J. A., Mitchell, J. A., Kerr, J., Hurvitz, P. M., Glanz, K., & Laden, F. (2017) · Cancer Epidemiology Biomarkers & Prevention · doi:10.1158/1055-9965.epi-16-0925 · Cited by 104 · see citing works
Exercise and the Immune System
Brolinson, P. G., & Elliott, D. (2007) · Clinics in Sports Medicine · doi:10.1016/j.csm.2007.04.011 · Cited by 103 · see citing works
The effects of endurance exercise on the heart: panacea or poison?
Parry-Williams, G., & Sharma, S. (2020) · Nature Reviews Cardiology · doi:10.1038/s41569-020-0354-3 · Cited by 102 · see citing works
Holzer, R., Bloch, W., & Brinkmann, C. K. (2022) · Sensors · doi:10.3390/s22052030 · Cited by 102 · see citing works
Schmidt, S., Monk, J. M., Robinson, L. E., & Mourtzakis, M. (2015) · Obesity Reviews · doi:10.1111/obr.12281 · Cited by 101 · see citing works
Association of Physical Activity with Development of Uterine Leiomyoma
Baird, D. D., Dunson, D. B., Hill, M. C., Cousins, D. S., & Schectman, J. M. (2006) · American Journal of Epidemiology · doi:10.1093/aje/kwj363 · Cited by 95 · see citing works
Energy balance and breast cancer risk: a prospective cohort study
Silvera, S. A. N., Jain, M. G., Howe, G. R., Miller, A. B., & Rohan, T. E. (2005) · Breast Cancer Research and Treatment · doi:10.1007/s10549-005-9098-3 · Cited by 93 · see citing works
S3 Guidelines for Colorectal Carcinoma
Schmiegel, W., Pox, C. P., Reinacher-Schick, A. C., Adler, G., Arnold, D., Fleig, W. E., Fölsch, U. R., Frühmorgen, P., Graeven, U., Heinemann, V., et al. (2010) · Zeitschrift für Gastroenterologie · doi:10.1055/s-0028-1109936 · Cited by 90 · see citing works
Diabetes and cancer II: role of diabetes medications and influence of shared risk factors
Onitilo, A. A., Engel, J. M., Glurich, I., Stankowski, R. V., Williams, G. M., & Doi, S. A. R. (2012) · Cancer Causes & Control · doi:10.1007/s10552-012-9971-4 · Cited by 89 · see citing works
Gómez, L. F., Sarmiento, O. L., Parra, D. C., Schmid, T. L., Pratt, M., Jacoby, E., Neiman, A. B., Cervero, R., Mosquera, J., Rutt, C., et al. (2010) · Journal of Physical Activity and Health · doi:10.1123/jpah.7.s2.s196 · Cited by 88 · see citing works
A systematic review of multimodal prehabilitation in breast cancer
Toohey, K. L., Hunter, M., McKinnon, K., Casey, T., Turner, M. R., Taylor, S., & Paterson, C. C. (2022) · Breast Cancer Research and Treatment · doi:10.1007/s10549-022-06759-1 · Cited by 87 · see citing works
Ruthirakuhan, M. T., Luedke, A. C., Tam, A., Goel, A., Kurji, A., & Garcia, A. A. (2012) · Journal of Aging Research · doi:10.1155/2012/384875 · Cited by 87 · see citing works
The Health Benefits of Exercise and Physical Activity
Miller, K. R., McClave, S. A., Jampolis, M. B., Hurt, R. T., Krueger, K. J., Landes, S., & Collier, B. C. (2016) · Current Nutrition Reports · doi:10.1007/s13668-016-0175-5 · Cited by 90 · see citing works
Effect of Community Volunteering on Physical Activity
Varma, V. R., Tan, E. J., Gross, A. L., Harris, G., Romani, W. A., Fried, L. P., Rebok, G. W., & Carlson, M. C. (2015) · American Journal of Preventive Medicine · doi:10.1016/j.amepre.2015.06.015 · Cited by 85 · see citing works
Gender Differences in Effects of Physical Activity on Quality of Life and Resource Utilization
Morimoto, T., Oguma, Y., Yamazaki, S., Sokejima, S., Nakayama, T., & Fukuhara, S. (2006) · Quality of Life Research · doi:10.1007/s11136-005-3033-2 · Cited by 83 · see citing works
Gómez, L. F., Duperly, J., Lucumí, D., Gámez, R., & Venegas, A. S. (2005) · Gaceta Sanitaria · doi:10.1157/13075953 · Cited by 83 · see citing works
Moulder, D. E., Hatoum, D., Tay, E. S. E., Lin, Y., & McGowan, E. M. (2018) · Cancers · doi:10.3390/cancers10060189 · Cited by 83 · see citing works
Molecular Targeted Drugs and Biomarkers in NSCLC, the Evolving Role of Individualized Therapy
Domvri, K., Zarogoulidis, P., Darwiche, K., Browning, R. F., Jr., Li, Q., Turner, J. F., Kioumis, I. P., Spyratos, D., Porpodis, Κ., Papaiwannou, A., et al. (2013) · Journal of Cancer · doi:10.7150/jca.7734 · Cited by 82 · see citing works
Kasuga, M., Ueki, K., Tajima, N., Noda, M., Ohashi, K., Noto, H., Goto, A., Ogawa, W., Sakai, R., Tsugane, S., et al. (2013) · Cancer Science · doi:10.1111/cas.12203 · Cited by 82 · see citing works
An exploration of walking behaviour—An interpretative phenomenological approach
Darker, C. D., Larkin, M., & French, D. (2007) · Social Science & Medicine · doi:10.1016/j.socscimed.2007.06.029 · Cited by 82 · see citing works
Dunston, E. R., Messina, E. S., Coelho, A. J., Chriest, S. N., Waldrip, M. P., Vahk, A., & Taylor, K. (2020) · Journal of American College Health · doi:10.1080/07448481.2020.1740229 · Cited by 90 · see citing works
Swim training suppresses tumor growth in mice
Almeida, P., Filho, A. G., Ferreira, A. J., Rodrigues, C. E. M., Dias‐Peixoto, M. F., Russo, R. C., Teixeira, M. M., Cassali, G. D., Ferreira, E. F., dos Santos, I. C., et al. (2009) · Journal of Applied Physiology · doi:10.1152/japplphysiol.00249.2009 · Cited by 80 · see citing works
Karoly, H. C., Stevens, C. J., Magnan, R. E., Harlaar, N., Hutchison, K. E., & Bryan, A. D. (2012) · Journal of Cancer Epidemiology · doi:10.1155/2012/540563 · Cited by 79 · see citing works
Cities and the Health of the Public
Freudenberg, N., Galea, S., & Vlahov, D. (2006) · Vanderbilt University Press eBooks · doi:10.2307/j.ctv1622mv6 · Cited by 44 · see citing works
Pan, S. Y., Mao, Y., & Ugnat, A. (2005) · American Journal of Epidemiology · doi:10.1093/aje/kwi342 · Cited by 75 · see citing works
Bigley, A. B., Spielmann, G., LaVoy, E. C. P., & Simpson, R. J. (2013) · Maturitas · doi:10.1016/j.maturitas.2013.06.010 · Cited by 75 · see citing works
Molecular Epidemiology of Physical Activity and Cancer
Rundle, A. (2005) · Cancer Epidemiology Biomarkers & Prevention · doi:10.1158/1055-9965.227.14.1 · Cited by 75 · see citing works
Physical activity in the prevention of cancer.
Kruk, J., & Aboul-Enein, H. Y. (2006) · PubMed · Cited by 74 · see citing works
Physical Activity Questionnaire Comprehension
Altschuler, A., Picchi, T., Nelson, M. C., Rogers, J., Hart, J. E., & Sternfeld, B. (2009) · Medicine & Science in Sports & Exercise · doi:10.1249/mss.0b013e318186b1b1 · Cited by 73 · see citing works
Stensvold, D., Viken, H., Rognmo, Ø., Skogvoll, E., Steinshamn, S., Vatten, L. J., Coombes, J. S., Anderssen, S. A., Magnussen, J., Ingebrigtsen, J. E., et al. (2015) · BMJ Open · doi:10.1136/bmjopen-2014-007519 · Cited by 70 · see citing works
Peel, J. B., Sui, X., Matthews, C. E., Adams, S. A., Hébert, J. R., Hardin, J. W., Church, T. S., & Blair, S. N. (2009) · Cancer Epidemiology Biomarkers & Prevention · doi:10.1158/1055-9965.epi-08-0846 · Cited by 69 · see citing works
S3-Guidelines Colorectal Cancer 2004
Schmiegel, W., Pox, C., Adler, G., Fleig, W. E., Fölsch, U. R., Frühmorgen, P., Graeven, U., Hohenberger, W., Holstege, A., Kühlbacher, T., et al. (2005) · DMW - Deutsche Medizinische Wochenschrift · doi:10.1055/s-2005-865098 · Cited by 69 · see citing works
Modifying Middle School Physical Education: Piloting Strategies to Increase Physical Activity
Jago, R., McMurray, R. G., Bassin, S., Pyle, L., Bruecker, S., Jakicic, J. M., Moe, E., Murray, T., & Volpe, S. L. (2009) · Pediatric Exercise Science · doi:10.1123/pes.21.2.171 · Cited by 67 · see citing works
Association of Physical Activity with Hormone Receptor Status: The Shanghai Breast Cancer Study
Adams, S. A., Matthews, C. E., Hébert, J. R., Moore, C. G., Cunningham, J. E., Shu, X.-O., Fulton, J., Gao, Y., & Zheng, W. (2006) · Cancer Epidemiology Biomarkers & Prevention · doi:10.1158/1055-9965.epi-05-0993 · Cited by 67 · see citing works
Moderate physical activity and breast cancer risk: the effect of menopausal status
Ángeles-Llerenas, A., Ortega-Olvera, C., Pérez‐Rodríguez, E., Esparza-Cano, J. P., Lazcano-Ponce, E. C., Romieu, I., & Torres-Mejı́a, G. (2010) · Cancer Causes & Control · doi:10.1007/s10552-009-9487-8 · Cited by 66 · see citing works
- Authors
- LEE, I.-M.
- Affiliations
- Brigham and Women's Hospital (US)
- Corresponding author
- LEE, I-MIN
- ORCID
- LEE, I-MIN
- Venue
- Medicine & Science in Sports & Exercise
- Published
- 2003-11
- Volume
- 35
- Issue
- 11
- Pages
- 1823-1827
- ISSN
- 0195-9131 (ISSN-L)
- OpenAlex
- W2034424159
- Cited by
- 436
- References
- 24
- Citations by year
- 2026: 2 · 2025: 5 · 2024: 4 · 2023: 15 · 2022: 18 · 2021: 16 · 2020: 19 · 2019: 17 · 2018: 14 · 2017: 19 · 2016: 25 · 2015: 19 · 2014: 25 · 2013: 23 · 2012: 28
- FWCI
- 9.83
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- Medicine & Science in Sports & Exercise (publishedVersion)
- PubMed (publishedVersion)
- Funders
- National Cancer Institute (R03CA091213, CA-91213)
- Topics
- Health Sciences › Medicine › Physiology › Physical Activity and Health
- Health Sciences › Medicine › Oncology › Cancer Risks and Factors
- Life Sciences › Biochemistry, Genetics and Molecular Biology › Molecular Biology › Metabolism, Diabetes, and Cancer
- Keywords
- physical activity, cancer prevention, colon cancer, rectal cancer, breast cancer, prostate cancer, lung cancer, dose-response relationship, moderate-to-vigorous intensity exercise, cancer risk
- MeSH terms
- Breast Neoplasms, Colonic Neoplasms, Female, Humans, Male, Motor Activity, Prostatic Neoplasms, Rectal Neoplasms, Risk, Exercise
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review
