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Sedentary time and cardio-metabolic biomarkers in US adults: NHANES 2003–06

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Healy, Genevieve N., Matthews, Charles E., Dunstan, David W., Winkler, Elisabeth A.H., Owen, Neville·2011·European Heart Journal

DOI 10.1093/eurheartj/ehq451PMC PMC3634159

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Abstract

AIMS: Prolonged sedentary time is ubiquitous in developed economies and is associated with an adverse cardio-metabolic risk profile and premature mortality. This study examined the associations of objectively assessed sedentary time and breaks (interruptions) in sedentary time with continuous cardio-metabolic and inflammatory risk biomarkers, and whether these associations varied by sex, age, and/or race/ethnicity. METHODS AND RESULTS: Cross-sectional analyses with 4757 participants (≥ 20 years) from the 2003/04 and 2005/06 US National Health and Nutrition Examination Survey (NHANES). An Actigraph accelerometer was used to derive sedentary time [< 100 counts per minute (cpm)] and breaks in sedentary time. Independent of potential confounders, including moderate-to-vigorous exercise, detrimental linear associations (P for trends < 0.05) of sedentary time with waist circumference, HDL-cholesterol, C-reactive protein, triglycerides, insulin, HOMA-%B, and HOMA-%S were observed. Independent of potential confounders and sedentary time, breaks were beneficially associated with waist circumference and C-reactive protein (P for trends <0.05). There was limited evidence of meaningful differences in associations with biomarkers by age, sex, or race/ethnicity. Notable exceptions were sex-differences in the associations of sedentary time and breaks with HDL-cholesterol, and race/ethnicity differences in the association of sedentary time with waist circumference with associations detrimental in non-Hispanic whites, null in Mexican Americans, and beneficial in non-Hispanic blacks. CONCLUSION: These are the first population-representative findings on the deleterious associations of prolonged sedentary time with cardio-metabolic and inflammatory biomarkers. The findings suggest that clinical communications and preventive health messages on reducing and breaking up sedentary time may be beneficial for cardiovascular disease risk.

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Physical Activity in the United States Measured by Accelerometer
TROIANO, R. P., BERRIGAN, D., DODD, K. W., MÂSSE, L. C., TILERT, T., & MCDOWELL, M. (2008) · Medicine & Science in Sports & Exercise · doi:10.1249/mss.0b013e31815a51b3 · Cited by 7,638
Physical Activity and Public Health: Updated Recommendation for Adults From the American College of Sports Medicine and the American Heart Association
(2007) · Circulation · doi:10.1161/circulationaha.107.185649 · Cited by 6,545
Calibration of the Computer Science and Applications, Inc. accelerometer
FREEDSON, P. S., MELANSON, E., & SIRARD, J. (1998) · Medicine & Science in Sports & Exercise · doi:10.1097/00005768-199805000-00021 · Cited by 3,825
Heart Disease and Stroke Statistics—2008 Update
Writing Group Members, Rosamond, W. D., Flegal, K. M., Furie, K. L., Go, A. S., Greenlund, K. J., Haase, N., Hailpern, S. M., Ho, M., Howard, V. J., et al. (2007) · Circulation · doi:10.1161/circulationaha.107.187998 · Cited by 3,799
National Center for Health Statistics (NCHS)
Feinleib, M. (2005) · Encyclopedia of Biostatistics · doi:10.1002/0470011815.b2a16042 · Cited by 3,134
Total energy intake: implications for epidemiologic analyses.
WILLETT, W., & STAMPFER, M. J. (1986) · American Journal of Epidemiology · doi:10.1093/oxfordjournals.aje.a114366 · Cited by 2,751
RE: “TOTAL ENERGY INTAKE: IMPLICATIONS FOR EPIDEMIOLOGIC ANALYSES”
Palmgren, J., & Kushi, L. H. (1991) · American Journal of Epidemiology · doi:10.1093/oxfordjournals.aje.a115841 · Cited by 2,712
Amount of Time Spent in Sedentary Behaviors in the United States, 2003-2004
Matthews, C. E., Chen, K. Y., Freedson, P. S., Buchowski, M. S., Beech, B. M., Pate, R. R., & Troiano, R. P. (2008) · American Journal of Epidemiology · doi:10.1093/aje/kwm390 · Cited by 2,631
Self-citation
C-reactive protein concentration and risk of coronary heart disease, stroke, and mortality: an individual participant meta-analysis
(2010) · The Lancet · doi:10.1016/s0140-6736(09)61717-7 · Cited by 2,546

Show all 28 references

Research works printed but not linked: 1

U.S. Department of Health and Human Services, 2005, U.S. Department of Agriculture. Dietary Guidelines for Americans

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Authors: Healy, G. N., Matthews, C. E., Dunstan, D. W., Winkler, E. A. H., & Owen, N.
Affiliations: Baker Heart and Diabetes Institute (AU)
National Cancer Institute (US)
The University of Queensland (AU)
Corresponding author: Healy, Genevieve N.
ORCID: Healy, Genevieve N.
Matthews, Charles E.
Dunstan, David W.
Winkler, Elisabeth A.H.
Owen, Neville
Venue: European Heart Journal
Publisher: Oxford University Press (OUP)
Published: 2011-01-11
Volume: 32
Issue: 5
Pages: 590-597
ISSN: 0195-668X (ISSN-L)
1522-9645
DOI: 10.1093/eurheartj/ehq451
PMC: PMC3634159
OpenAlex: W2150722389
Cited by: 1,368
References: 28
Citations by year: 2026: 21 · 2025: 31 · 2024: 49 · 2023: 57 · 2022: 80 · 2021: 94 · 2020: 106 · 2019: 102 · 2018: 104 · 2017: 125 · 2016: 112 · 2015: 146 · 2014: 135 · 2013: 102 · 2012: 71
FWCI: 73.71
Type: journal article
Language: en
Open access: bronze
doi.org
Locations: European Heart Journal (publishedVersion)
Europe PMC (PubMed Central) (publishedVersion)
PubMed Central (publishedVersion)
PubMed (publishedVersion)
Research Bank (Australian Catholic University) (submittedVersion)
eSpace (Curtin University) (submittedVersion)
Figshare (submittedVersion, cc-by)
Swinburne figshare (Swinburne University of Technology) (submittedVersion)
Funders: National Institutes of Health (Z99 CA999999)
Topics: Health Sciences › Medicine › Public Health, Environmental and Occupational Health › Physical Activity and Health
Health Sciences › Medicine › Endocrinology, Diabetes and Metabolism › Adipokines, Inflammation, and Metabolic Diseases
Health Sciences › Medicine › Pharmacology (medical) › Coffee research and impacts
Keywords: sedentary behavior, sedentary breaks, cardiometabolic risk, inflammatory markers, C-reactive protein, waist circumference, HDL cholesterol, triglycerides, insulin, HOMA-IR, HOMA-β, accelerometer-measured sedentary time, sex differences, racial and ethnic differences, cardiovascular risk, NHANES
MeSH terms: Acceleration, Adult, Aged, Blood Pressure, Cardiovascular Diseases, Cross-Sectional Studies, Female, Humans, Male, Middle Aged, Nutrition Surveys, Smoking, United States, Biomarkers, Age Distribution, Sex Distribution, Waist Circumference, Sedentary Behavior

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Sedentary time and cardio-metabolic biomarkers in US adults: NHANES 2003–06

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