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Cited by 685

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Sarcopenia: Current Concepts

Roubenoff, R., Hughes, V. A.·2000·The Journals of Gerontology Series A: Biological Sciences and Medical Sciences
DOI 10.1093/gerona/55.12.m716
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Abstract

Sarcopenia, the loss of muscle mass and strength with age, is becoming recognized as a major cause of disability and morbidity in the elderly population. Sarcopenia is part of normal aging and does not require a disease to occur, although muscle wasting is accelerated by chronic diseases. Sarcopenia is thought to have multiple causes, although the relative importance of each is not clear. Neurological, metabolic, hormonal, nutritional, and physical-activity-related changes with age are likely to contribute to the loss of muscle mass. In this review, we discuss current concepts of the pathogenesis, treatment, and prevention of sarcopenia.

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Metadata

Authors
Roubenoff, R., & Hughes, V. A.
Venue
The Journals of Gerontology Series A: Biological Sciences and Medical Sciences
Publisher
Oxford University Press (OUP)
Published
2000-12-01
Volume
55
Issue
12
Pages
M716-M724
ISSN
  • 1079-5006 (ISSN-L)
  • 1758-535X
DOI
10.1093/gerona/55.12.m716
OpenAlex
W2097971520
Cited by
685
References
20
FWCI
11.34
Type
journal article
Language
en
Open access
closed

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Roubenoff, R., & Hughes, V. A. (2000). Sarcopenia: Current Concepts. The Journals of Gerontology Series A: Biological Sciences and Medical Sciences. https://doi.org/10.1093/gerona/55.12.m716

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