Cited by 7Gun Ownership and Violence ResearchMachine Learning in HealthcareArtificial Intelligence in Healthcare

Machine learning classification of new firearm injury encounters in the St Louis region: 2010-2020

Open access
Ancona, Rachel M, Cooper, Benjamin P, Foraker, Randi, Kaser, Taylor, Adeoye, Opeolu, Mueller, Kristen L·2024·Journal of the American Medical Informatics Association

Abstract

Objectives: To improve firearm injury encounter classification (new vs follow-up) using machine learning (ML) and compare our ML model to other common approaches. Materials and Methods: This retrospective study used data from the St Louis region-wide hospital-based violence intervention program data repository (2010-2020). We randomly selected 500 patients with a firearm injury diagnosis for inclusion, with 808 total firearm injury encounters split (70/30) for training and testing. We trained a least absolute shrinkage and selection operator (LASSO) regression model with the following predictors: admission type, time between firearm injury visits, number of prior firearm injury emergency department (ED) visits, encounter type (ED or other), and diagnostic codes. Our gold standard for new firearm injury encounter classification was manual chart review. We then used our test data to compare the performance of our ML model to other commonly used approaches (proxy measures of ED visits and time between firearm injury encounters, and diagnostic code encounter type designation [initial vs subsequent or sequela]). Performance metrics included area under the curve (AUC), sensitivity, and specificity with 95% confidence intervals (CIs). Results: The ML model had excellent discrimination (0.92, 0.88-0.96) with high sensitivity (0.95, 0.90-0.98) and specificity (0.89, 0.81-0.95). AUC was significantly higher than time-based outcomes, sensitivity was slightly (but not significantly) lower than other approaches, and specificity was higher than all other methods. Discussion: ML successfully delineated new firearm injury encounters, outperforming other approaches in ruling out encounters for follow-up. Conclusion: ML can be used to identify new firearm injury encounters and may be particularly useful in studies assessing re-injuries.

AI snapshot

Written from the paper’s full text.

TL;DR

A LASSO machine learning model using encounter and diagnostic-code features classified new versus follow-up firearm injury encounters with high discrimination and specificity, outperforming time-based rules and matching or exceeding ED-visit and ICD-10 encounter-type proxies on several metrics. The authors conclude ML can improve identification of new firearm injury encounters, especially for ruling out follow-up care.

Key findings

  • In the test set (N=241), the ML model had AUC 0.92 (0.88–0.96), sensitivity 0.95 (0.90–0.98), specificity 0.89 (0.81–0.95), PPV 0.93 (0.88–0.97), NPV 0.91 (0.83–0.96), and accuracy 92.5% (223/241 correctly classified).
  • ML had the highest AUC; it was significantly higher than all time-based classifications but not significantly higher than ED visits or ICD-10 encounter-type coding. ML specificity was significantly higher than all other methods, and PPV was significantly higher than ICD-10 encounter type and all time-based classifications.
  • ICD-10 encounter-type coding had sensitivity 1.00 and was described as superior for capturing all new injury encounters; ED visits were a reasonable proxy for pre-ICD-10 data. Time-based classification had no utility at <3 days, fair utility at 90 days, and good utility at >120 days.
  • Agreement with manual review was highest for ML (K=0.84; 0.77–0.91), though not significantly higher than ICD-10 codes (0.73), ED visits (0.69), or >120 days (0.68). No significant accuracy differences by race or sex were found.

Methods

  • Retrospective study using the St Louis region-wide hospital-based violence intervention program data repository (2010–2020). From 22 574 firearm-injury encounters, 500 patients with 808 encounters were randomly selected for manual review; final model dataset included 499 patients and 803 encounters, split 70/30 into training (562 encounters/337 patients) and testing (241 encounters/162 patients). ICD-10-specific evaluation used 151 encounters from 120 patients.
  • Gold standard was manual chart review by two clinical providers, with discordant encounters adjudicated by a third reviewer; agreement was 753/808 (93.2%; Kappa=0.861).
  • LASSO regression with 10-fold cross-validation (best lambda=0.008) used predictors including admission type, time between firearm injury visits, number of prior firearm injury ED visits, encounter type (ED or other), and diagnostic codes; 1745 covariates were reduced to 61 variables in the final model. Performance was compared with ED visits, time cutoffs (1, 3, 90, and optimal >120 days), and ICD-10 initial vs subsequent/sequela coding using AUC, sensitivity, specificity, PPV, NPV, accuracy, and Kappa.

Limitations

  • The paper states that data were lacking for patients who sought care at non-trauma hospitals, non-acute care, or no care; it notes an estimated 30.5% seek care at non-trauma centers and that this could affect findings, particularly time-based approaches.
  • The paper states limited generalizability to Native American/Alaska Native and Hispanic populations, and that non-Black and non-male sample sizes were small, so undetected bias may remain.
  • The paper states that diagnostic-code models require ongoing evaluation because ICD codes evolve; it also notes the time-based assessment was limited to 36 subsequent encounters among 241 test encounters and variable cohort entry times. Evident from the text: the model was developed and tested in a single region and relied on manual review of a randomly selected subset rather than the full repository.

Model-written summary. Check it against the paper before relying on it.

Integrity signals

Registry

Crossref · 10.1093/jamia/ocae173

Cites

26 of 26 references verified0 citation errors · 0 not checkable

Statistics

Nothing to recompute.

Claims the paper makes

19 of 29 cited sources checked · 10 supported · 1 flagged · accuracy not yet measured

  • Premisecitation

    It is estimated that 20% of patients with a firearm injury will be readmitted to the hospital within 90 days.

    “In fact, it is estimated that 20% of patients with a firearm injury will be readmitted to the hospital within 90 days.3”
    Quote in the paperNot a substantial claim1 of 1 sources checked
    • cites [3] Kalesan, 2019, Risk of 90-day readmission in patients after firearm injury hospitalization: a nationally representative retrospective cohort study, J Inj Violence Res source

      The Results section reports a 10.5% absolute 90-day readmission rate among firearm-injury patients, not 20%. Its 20% figure describes the higher relative risk compared with pedestrians, not the proportion of firearm-injury patients readmitted. No page number is provided in our copy. (LLM, conf=0.93)

      Checked by a reasoning model — may be wrong.

      Experimental — accuracy not yet measured
  • Premisecitation

    It is estimated that 30.5% of patients seek care at a non-trauma center.

    “It is estimated that 30.5% of patients seek care at a non-trauma center.31”
    Quote in the paperNot a substantial claim1 of 1 sources checked
    • cites [31] Coupet, 2019, US Emergency Department encounters for firearm injuries according to presentation at trauma vs nontrauma centers, JAMA Surg source
  • Findingown data

    Of the 241 firearm injury encounters in the test dataset, 36 (14.9%) had more than one injury encounter.

    “Of the 241 firearm injury encounters in the test dataset, 36 (14.9%) had more than one injury encounter.”
    Quote in the paperSubstantial claim
  • Findingown data

    The ML model had PPV of 0.93 (95% CI 0.88-0.97).

    “given an AUC of 0.92 (0.88, 0.96), sensitivity of 0.95 (0.90, 0.98), specificity of 0.89 (0.81, 0.95), PPV of 0.93 (0.88, 0.97), and NPV of 0.91 (0.83, 0.96).”
    Quote in the paperSubstantial claim
  • Findingown data

    The ML model had an AUC of 0.92 (95% CI 0.88-0.96) in the test dataset.

    “The ML model had excellent discrimination (0.92, 0.88-0.96)with high sensitivity (0.95, 0.90-0.98)and specificity (0.89, 0.81-0.95).”
    • Also stated in: § Results · plain
      “given an AUC of 0.92 (0.88, 0.96), sensitivity of 0.95 (0.90, 0.98), specificity of 0.89 (0.81, 0.95), PPV of 0.93 (0.88, 0.97), and NPV of 0.91 (0.83, 0.96).”
    Quote in the paperSubstantial claim
  • Classified as probably not a substantial claim. 20
  • May combine two claims. 18
  • Probably not a substantial claim: may not pass S1 (asserted), S3 (load-bearing).

    Premisecitation

    The FACTS Consortium stated a need for a greater focus on collecting longitudinal data that tests new and existing theoretical models to understand the epidemiology of firearm carriage, risky firearm behaviors, and firearm violence among adolescent and emerging adult populations.

    “According to the Firearm Safety among Children and Teens (FACTS) Consortium (funded in 2017 by the National Institutes of Health), there is a need”
    Quote in the paperNot a substantial claim1 of 1 sources checked
    • cites [16] Cunningham, 2019, Prevention of firearm injuries among children and adolescents: consensus-driven research agenda from the Firearm Safety Among Children and Teens (FACTS) consortium, JAMA Pediatr source

      The Discussion’s Data Enhancement section calls for research guided by theoretical models and for longitudinal data collection to understand firearm behavior and causal relationships. The Epidemiology and Risk and Protective Factors section also discusses youth firearm carriage. But the paper frames its agenda around children and adolescents, not emerging adults, and does not specifically call for longitudinal tests of new and existing models of all three named outcomes. Page numbers were not available in our copy. (LLM, conf=0.85)

      Experimental — accuracy not yet measured
  • Probably not a substantial claim: may not pass S3 (load-bearing).

    Premisecitation

    The time-based approach is most often applied to studies of firearm injury recurrence, with days since prior injury ranging from 1 to 90 days depending on the study.

    “The time-based approach is most often applied to studies of firearm injury recurrence, with days since prior injury ranging from 1 to 90 days, depending on the study [7][8][9]”
    Quote in the paperNot a substantial claim1 of 3 sources checked
    • cites [7] Kaufmann, 1998, A population-based study of trauma recidivism, J Trauma source
    • cites [8] Rowhani-Rahbar, 2015, Firearm-related hospitalization and risk for subsequent violent injury, death, or crime perpetration: a cohort study, Ann Intern Med source
    • cites [9] Carter, 2017, Individual and neighborhood characteristics of children seeking emergency department care for firearm injuries within the PECARN network, Acad Emerg Med source

      The Methods (Data Analysis; page unavailable) use a time window to assess firearm-injury recidivism, supporting this paper as an example of a time-based approach. But the window is 12 months before and after the index visit, with returns within 72 hours excluded—not a 1-to-90-day window. This paper also does not establish how often the approach is used across studies. (LLM, conf=0.85)

      Experimental — accuracy not yet measured
  • Classified as probably not a substantial claim.

    Premisecitation

    Previous literature has highlighted discrepancies in diagnostic code validity concerning firearm injury encounter intent.

    “Previous literature has highlighted discrepancies in diagnostic code validity concerning firearm injury encounter intent (unintentional, intentional self-harm, assault, legal intervention, undetermined, or war and conflict).4”
    Quote in the paperSubstantial claim1 of 1 sources checked
    • cites [4] Miller, 2022, Assessment of the accuracy of firearm injury intent coding at 3 US hospitals, JAMA Netw Open source
  • Probably not a substantial claim: may not pass S2 (checkable).

    Premisecitation

    Advanced computational techniques, such as ML and natural language processing, are promising ways to address diagnostic classification problems where issues with ICD coding persist.

    “Advanced computational techniques, such as ML and natural language processing (NLP), are promising ways to address diagnostic classification problems where issues with ICD coding persist.11,15”
    Quote in the paperNot a substantial claim1 of 2 sources checked
    • cites [11] Pear, 2020, Risk factors for assaultive reinjury and death following a nonfatal firearm assault injury: a population-based retrospective cohort study, Prev Med source
    • cites [15] MacPhaul, 2023, Classifying firearm injury intent in electronic hospital records using natural language processing, JAMA Netw Open source
  • Probably not a substantial claim: may not pass S3 (load-bearing).

    Premisecitation

    The homicide death ratio affiliated with firearms is 5 times higher in men than in women.

    “The homicide death ratio affiliated with firearms is 5 times higher in men than in women.22”
    Quote in the paperNot a substantial claim1 of 1 sources checked
    • cites [22] Young, 2022, US racial and sex-based disparities in firearm-related death trends from 1981-2020, PLoS One source
  • Probably not a substantial claim: may not pass S3 (load-bearing).

    Study design and conductnone given

    The study followed the TRIPOD checklist in this report.

    “We followed the TRIPOD checklist in this report.18”
    Quote in the paperNot a substantial claim1 of 1 sources checked
    • cites [18] Collins, 2015, Transparent Reporting of a multivariable prediction model for Individual Prognosis Or Diagnosis (TRIPOD): the TRIPOD statement, Br J Surg source
  • Classified as probably not a substantial claim. May combine two claims.

    Premisecitation

    Two proxy measures commonly used in the existing literature are ED visits and time between firearm injury encounters.

    “Two proxy measures commonly used in the existing body of literature are (1) ED visits and (2) time between firearm injury encounters.2,4-9”
    Quote in the paperSubstantial claim5 of 7 sources checked
    • cites [2] Kaufman, 2021, Epidemiologic trends in fatal and nonfatal firearm injuries in the US, 2009-2017, JAMA Intern Med source

      The Abstract and the section on data sources show that this paper uses emergency department visits to estimate nonfatal firearm injuries and describes earlier work using ED data. The passages do not identify time between firearm injury encounters as a measure used in the literature; searches for that phrase and for proxy measures found no such discussion. (LLM, conf=0.86)

      Experimental — accuracy not yet measured
    • cites [4] Miller, 2022, Assessment of the accuracy of firearm injury intent coding at 3 US hospitals, JAMA Netw Open source

      The Introduction (page not available) describes hospital data on patients presenting to emergency departments as a major source of information about nonfatal firearm injuries, supporting the ED-visit part in a broad sense. The paper does not identify ED visits as a commonly used proxy measure or discuss time between firearm injury encounters as a measure. (LLM, conf=0.76)

      Experimental — accuracy not yet measured
    • cites [5] Miller, 2024, Costs of fatal and nonfatal firearm injuries in the U.S., 2019 and 2020, Am J Prev Med source

      The Discussion (page unavailable) says most current cost studies use emergency-department and inpatient datasets, supporting the narrower point that ED-based data are commonly used in that literature. It does not describe ED visits as a proxy measure or identify time between firearm-injury encounters as a commonly used measure; searches for those terms found no supporting passage. (LLM, conf=0.78)

      Experimental — accuracy not yet measured
    • cites [6] Schnippel, 2021, Nonfatal firearm injuries by intent in the United States: 2016-2018 hospital discharge records from the healthcare cost and utilization project, West J Emerg Med source

      The Discussion describes prior analyses based on emergency-department visits, supporting ED visits as a measure used in the literature. It also mentions 30- and 90-day readmissions, but does not identify time between firearm injury encounters as a commonly used proxy measure. The Methods and Results count injury episodes rather than measuring intervals between them. (LLM, conf=0.84)

      Experimental — accuracy not yet measured
    • cites [7] Kaufmann, 1998, A population-based study of trauma recidivism, J Trauma source
    • cites [8] Rowhani-Rahbar, 2015, Firearm-related hospitalization and risk for subsequent violent injury, death, or crime perpetration: a cohort study, Ann Intern Med source
    • cites [9] Carter, 2017, Individual and neighborhood characteristics of children seeking emergency department care for firearm injuries within the PECARN network, Acad Emerg Med source

      The Methods (Data Analysis; page unavailable) identify repeat ED visits within 12 months of an index firearm injury, and the Results (Emergency Department Outcomes and Recidivism; page unavailable) report subsequent visits and firearm injuries. This supports ED visits as a measure, but the paper does not report time between separate firearm injury encounters as a measured interval; its 12-month follow-up window is not that measure. (LLM, conf=0.83)

      Experimental — accuracy not yet measured
  • Probably not a substantial claim: may not pass S3 (load-bearing). May combine two claims.

    Premisecitation

    People in the Black racial group have a firearm-related homicide mortality rate 7 times higher than those in the White racial group and 5 times higher than those in the American Indian/Alaska Native racial group.

    “People in the Black racial group have a firearm-related homicide mortality rate 7 times higher than those in the White racial group and 5 times higher than those in the American Indian/Alaska Native racial group (race with second highest rate).22”
    Quote in the paperNot a substantial claim1 of 1 sources checked
    • cites [22] Young, 2022, US racial and sex-based disparities in firearm-related death trends from 1981-2020, PLoS One source
  • May combine two claims.

    Premisecitation

    Firearm injury disproportionately affects males and Black individuals.

    “Firearm injury disproportionately affects males and black individuals.”
    Quote in the paperSubstantial claim2 of 2 sources checked
    • cites [22] Young, 2022, US racial and sex-based disparities in firearm-related death trends from 1981-2020, PLoS One source

      The Results report substantially higher firearm homicide and suicide death rates for men than women, and higher firearm homicide death rates for Black people than White people. But the paper studies deaths, not firearm injury generally; it also reports that White people had the highest firearm suicide death rate. (LLM, conf=0.83)

      Experimental — accuracy not yet measured
    • cites [5] Miller, 2024, Costs of fatal and nonfatal firearm injuries in the U.S., 2019 and 2020, Am J Prev Med source
  • Probably not a substantial claim: may not pass S2 (checkable).

    Interpretationreasoning

    These findings meaningfully impact the rigor of clinical research designed to evaluate the epidemiology of new and recurrent firearm injury encounters across populations as well as re-injury evaluations of violence and injury intervention programs.

    “These findings also meaningfully impact the rigor of clinical research designed to evaluate the epidemiology of new and recurrent firearm injury encounters across populations as well as re-injury evaluations of violence and injury intervention programs (eg, hospital-based violence intervention programs).12”
    Quote in the paperNot a substantial claim1 of 1 sources checked
    • cites [12] Mueller, 2023, Incidence of and factors associated with recurrent firearm injury among patients presenting to St Louis trauma centers, 2010 to 2019: a cohort study, Ann Intern Med source
    • Rests on an assumption: Manual review correctly identifies new firearm injury encounters.
  • Probably not a substantial claim: may not pass S3 (load-bearing). May combine two claims.

    Premisecitation

    ML has been used to classify new firearm injury encounters by our team and by one other published study.

    “Machine learning (ML) has also been used to classify new firearm injury encounters by our team, and we are aware of one other published study that has also used ML to classify new firearm injury encounters.11,12”
    Quote in the paperNot a substantial claim1 of 2 sources checked
    • cites [11] Pear, 2020, Risk factors for assaultive reinjury and death following a nonfatal firearm assault injury: a population-based retrospective cohort study, Prev Med source
    • cites [12] Mueller, 2023, Incidence of and factors associated with recurrent firearm injury among patients presenting to St Louis trauma centers, 2010 to 2019: a cohort study, Ann Intern Med source
  • Probably not a substantial claim: may not pass S3 (load-bearing).

    Premisecitation

    Trends are similar for nonfatal firearm injuries.

    “Trends are similar for nonfatal firearm injuries as well.5”
    Quote in the paperNot a substantial claim1 of 1 sources checked
    • cites [5] Miller, 2024, Costs of fatal and nonfatal firearm injuries in the U.S., 2019 and 2020, Am J Prev Med source
  • May combine two claims.

    Findingown data

    Agreement (Kappa) was highest for the ML model (0.84; 95% CI 0.77-0.91), but not significantly higher than ICD-10 codes (0.73; 0.62-0.84), ED visits (0.69; 0.60-0.79), or encounters after 120 days (0.68; 0.59-0.78).

    “Agreement (K) was also highest for the ML model (0.84; 0.77, 0.91), but not significantly higher than ICD-10 codes (0.73; 0.62, 0.84), ED visits (0.69; 0.60, 0.79), or encounters after 120 days (0.68; 0.59, 0.78).”
    Quote in the paperNot a substantial claim
  • May combine two claims.

    Findingown data

    For time-based classifications, sensitivity remained constant while specificity and AUC increased as the number of days increased.

    “Sensitivity for time-based classifications remained constant, with increasing specificity and thus increasing AUC, as the number of days increased (Table 3).”
    Quote in the paperNot a substantial claim
  • May combine two claims.

    Findingown data

    The ML model predicted 153/241 (63.5%) encounters were acute firearm injuries, compared to 151/241 (62.7%) classified by the gold standard.

    “The ML model predicted 153/241 (63.5%) encounters were acute firearm injuries, compared to 151/241 (62.7%) classified by the gold standard, with an overall accuracy of 92.5% (223/241 correctly classified).”
    Quote in the paperSubstantial claim
  • May combine two claims.

    Findingown data

    The distribution of days between injuries was right-skewed, with the majority of values (25, 69.4%) less than or equal to 120 days.

    “The distribution was rightskewed, with the majority of values (25, 69.4%) less than or equal to 120 days.”
    Quote in the paperNot a substantial claim
  • May combine two claims.

    Findingown data

    The minimum squared Euclidian distance between sensitivity and specificity was 0.97 at 121 days, and greater than 120 days was selected as the optimal cut-off value for time between firearm injury encounters.

    “The minimum Euclidian distance between sensitivity and specificity squared was 0.97 (range: 0.97-1.61),at 121 days.Therefore, we selected greater than 120 days as our optimal cut-off value for time between firearm injury encounters as a classification approach.”
    Quote in the paperSubstantial claim
  • Probably not a substantial claim: may not pass S2 (checkable), S3 (load-bearing).

    Interpretationreasoning

    Any classification model using diagnostic codes necessitates ongoing model evaluation and, potentially, modification.

    “This means that any classification model using diagnostic codes necessitates ongoing model evaluation and, potentially, modification.”
    Quote in the paperNot a substantial claim
    • Rests on an assumption: ICD-10 codes are updated regularly to include new diagnoses.
  • May combine two claims.

    Study design and conductcitation

    The model's effect size (AUC converted to Cohen's D of 2.0) and accuracy (93%) were both above sufficient sample size thresholds (0.50 and 80%, respectively).

    “Considering the sample size criteria proposed by Rajput et al., the model's effect size (AUC converted to a Cohen's D of 2.0) and its accuracy (93%) were both well above sufficient sample size thresholds (0.50 and 80%, respectively).”
    Quote in the paperNot a substantial claim0 of 1 sources checked
    • cites Rajput et al.

      Couldn’t be matched to a paper in Crossref, so it can’t be checked.

  • Probably not a substantial claim: may not pass S3 (load-bearing).

    Premisecitation

    A study from 2000 surveyed 93 incarcerated men and found that 8% of them did not seek medical care for their last firearm injury.

    “we did find a study from 2000 that surveyed 93 incarcerated men and found that 8% of them did not seek medical care for their last firearm injury.32”
    Quote in the paperNot a substantial claim0 of 1 sources checked
    • cites [32] May, 2000, Medical care solicitation by criminals with gunshot wound injuries: a survey of Washington, DC, jail detainees, J Trauma source
  • Classified as probably not a substantial claim. May combine two claims.

    Study design and conductnone given

    LASSO regression was used to develop the model, which was cross-validated (k = 10) to identify the best lambda to tune the final model to avoid overfitting.

    “We used LASSO regression to develop the model, which was then cross-validated (k ¼ 10) to identify the best lambda to tune the final model to avoid overfitting.”
    Quote in the paperSubstantial claim
  • Probably not a substantial claim: may not pass S3 (load-bearing).

    Study design and conductnone given

    A limitation of the model (or any model built using diagnostic codes) is the evolving nature of ICD codes since ICD-10 codes are updated regularly to include new diagnoses.

    “a limitation of our model (or any model built using diagnostic codes) is the evolving nature of ICD codes since ICD-10 codes are updated regularly to include new diagnoses.”
    Quote in the paperNot a substantial claim
    • Rests on an assumption: ICD-10 codes are updated regularly to include new diagnoses.
  • May combine two claims.

    Interpretationown data

    ML can be used to identify new firearm injury encounters and may be particularly useful in studies assessing re-injuries.

    “ML can be used to identify new firearm injury encounters and may be particularly useful in studies assessing re-injuries.”
    Quote in the paperSubstantial claim
  • May combine two claims.

    Interpretationown data

    The ML model performed well and appeared well-balanced in both capturing new firearm injury encounters and ruling out follow-up encounters for prior injuries.

    “The model performed well and appears to be well-balanced in both capturing new firearm injury encounters and ruling out follow-up encounters for prior injuries given an AUC of 0.92 (0.88, 0.96), sensitivity of 0.95 (0.90, 0.98), specificity of 0.89 (0.81, 0.95), PPV of 0.93 (0.88, 0.97), and NPV of 0.91 (0.83, 0.96).”
    Quote in the paperSubstantial claim
  • Probably not a substantial claim: may not pass S3 (load-bearing). May combine two claims.

    Study design and conductnone given

    Missing injury severity scores were coded as zero and missing admission type was added as an additional category for that variable.

    “Missing injury severity scores were coded as zero and missing admission type was added as an additional category for that variable.”
    Quote in the paperNot a substantial claim
  • Probably not a substantial claim: may not pass S3 (load-bearing).

    Study design and conductown data

    The study tested for differences in accuracy for sex and race.

    “We did test for differences in accuracy for sex and race”
    Quote in the paperNot a substantial claim
    • Rests on an assumption: Manual review correctly identifies new firearm injury encounters.
  • May combine two claims.

    Interpretationown data

    Other approaches to classifying new firearm injury encounters likely yield over-estimates, particularly if they use a time-based cut-off less than 90 days, and to a lesser extent if using ED visits as a proxy measure or ICD-10 encounter type.

    “Other approaches to classifying new firearm injury encounters likely yield over-estimates, particularly if they use a time-based cut-off less than 90 days, and to a lesser extent if using ED visits as a proxy measure or ICD-10 encounter type.”
    Quote in the paperSubstantial claim
    • Rests on an assumption: Manual review correctly identifies new firearm injury encounters.
  • Probably not a substantial claim: may not pass S3 (load-bearing).

    Interpretationcitation

    The results of the primary outcome align with the work of Pear et al., who also reported a high AUC using an ML model for classifying firearm injury visit type.

    “The results of our primary outcome align with the work of Pear et al., who also reported a high AUC using an ML model for classifying firearm injury visit type.11”
    Quote in the paperNot a substantial claim0 of 1 sources checked
    • cites [11] Pear, 2020, Risk factors for assaultive reinjury and death following a nonfatal firearm assault injury: a population-based retrospective cohort study, Prev Med source
    • Rests on an assumption: Manual review correctly identifies new firearm injury encounters.
  • May combine two claims.

    Interpretationown data

    ML successfully delineated new firearm injury encounters and outperformed other approaches in ruling out encounters for follow-up.

    “ML successfully delineated new firearm injury encounters, outperforming other approaches in ruling out encounters for follow-up.”
    Quote in the paperSubstantial claim
    • Rests on an assumption: Manual chart review is a valid gold standard for classifying a firearm injury encounter as a new injury or a follow-up visit.
  • Probably not a substantial claim: may not pass S3 (load-bearing), S4 (based). May combine two claims.

    Study design and conductnone given

    The sample in the study is representative of its region, which has a limited number of individuals in these populations.

    “The sample in our study is representative of its region, which has a limited number of individuals in these populations.”
    Quote in the paperNot a substantial claim
    • Rests on an assumption: The sample in the study is representative of its region.
  • Probably not a substantial claim: may not pass S2 (checkable), S3 (load-bearing).

    Interpretationreasoning

    This could have impacted the findings, particularly with time-based approaches.

    “This could have impacted our findings, particularly with time-based approaches.”
    Quote in the paperNot a substantial claim
  • May combine two claims.

    Premisecitation

    The precision of classification methods remains unestablished and comparisons between these methods have not been published.

    “While the variability of classification methods is known, and was recently (2023) described in a systematic review on firearm injury recurrence, the precision of these methods remain unestablished and comparisons between these methods, to our knowledge, have not been published.13”
    Quote in the paperSubstantial claim0 of 1 sources checked
    • cites [13] Shayan, 2023, A systematic review of recurrent firearm injury rates in the United States, Prev Med source
32 of 32
  • The paper relies on this without support.

    Those who survive firearm injuries are at high risk of recurrent firearm injury.

    “Those who survive firearm injuries are a key target for secondary prevention intervention strategies (eg, hospital-based violence intervention programs) due to their high risk of recurrent firearm injury.”
  • The paper relies on this without support.

    Firearm injuries are often severe and routinely necessitate multiple healthcare encounters as part of post-acute care or to treat complications and new conditions that are sequela of the initial injury.

    “Firearm injuries are often severe, routinely necessitating multiple healthcare encounters as part of routine post-acute care or to treat complications and new conditions that were sequela of the initial injury.”
  • The paper relies on this without support.

    Follow-up encounters for firearm injuries obfuscate the true incidence of new firearm injury encounters and assessments of firearm injury recurrence in hospital data due to diagnostic coding limitations.

    “Due to diagnostic coding limitations, these follow-up encounters for firearm injuries obfuscate the true incidence of new firearm injury encounters and assessments of firearm injury recurrence in hospital data.”
  • The paper relies on this without support.

    There is no reason to believe that individuals from different sexes or races would differ clinically when presenting for a firearm injury.

    “There is also no reason to believe that individuals from different sexes or races would differ clinically when presenting for a firearm injury.”
  • The paper relies on this without support.

    Manual chart review is a valid gold standard for classifying a firearm injury encounter as a new injury or a follow-up visit.

    “Our gold standard for new firearm injury encounter classification was manual chart review.”
    “The gold standard for the outcome variable, classification of a firearm injury encounter as new or follow-up was defined by manual review (described above in the participant and encounter selection section).”
  • The paper relies on this without support.

    Coding limitations persist across healthcare settings, potentially leading to misclassification.

    “Yet coding limitations persist across healthcare settings, potentially leading to misclassification.”
  • The paper relies on this without support.

    ICD-10 enhanced coding to specify whether an encounter was initial, subsequent, or sequela, whereas ICD-9 lacked specificity regarding encounter type.

    “ICD-9 lacked specificity regarding encounter type; whereas ICD-10 enhanced coding to specify if the encounter was initial, subsequent (part of recovery care), or sequela (complications or conditions that arise from a prior injury).”
  • The paper relies on this without support.

    Manual review correctly identifies new firearm injury encounters.

    “Classification of new firearm injury encounters, comparing all methods to manual review.”
  • The paper relies on this without support.

    ICD-10 codes are updated regularly to include new diagnoses.

    “ICD-10 codes are updated regularly to include new diagnoses.”
  • The paper relies on this without support.

    The sample in the study is representative of its region.

    “The sample in our study is representative of its region”
10 of 10

Self-check

Percentages, sums and reported differences re-computed from the paper’s own numbers.

  • Dual Medicaid/Medicare subgroup counts do not add up

    Minor

    The training and testing counts sum to 5, but the manual-review total is 9.

    Reported 9 · recomputed 5

  • Medicare subgroup counts exceed the manual-review total

    Minor

    The training and testing counts sum to 9, but the manual-review total is 5.

    Reported 5 · recomputed 9

2 of 2

Cites

Flagged first, then by citations

Research works printed but not linked: 1

  1. Byrne, 2024, Artificial Intelligence for Improved Patient Outcomes

Cited by

Sorted by citations

Authors
Ancona, R. M., Cooper, B. P., Foraker, R., Kaser, T., Adeoye, O., & Mueller, K. L.
Affiliations
Washington University in St. Louis (US)
Corresponding author
Ancona, Rachel M
Venue
Journal of the American Medical Informatics Association
Published
2024-07-08
Volume
31
Issue
10
Pages
2165-2172
ISSN
  • 1067-5027 (ISSN-L)
  • 1527-974X
OpenAlex
W4400409593
Cited by
7
References
26
Citations by year
2026: 3 · 2025: 2 · 2024: 2
FWCI
3.03
Type
journal article
Language
en
Open access
Locations
  • Journal of the American Medical Informatics Association (publishedVersion)
  • PubMed (publishedVersion)
  • Europe PMC (PubMed Central) (submittedVersion)
  • PubMed Central (submittedVersion)
Funders
  • National Institutes of Health
  • Eunice Kennedy Shriver National Institute of Child Health & Human Development (K23HD107520)
Topics
  • Social Sciences › Health › Gun Ownership and Violence Research
  • Physical Sciences › Computer Science › Artificial Intelligence › Machine Learning in Healthcare
  • Health Sciences › Health Professions › Health Information Management › Artificial Intelligence in Healthcare
Keywords
firearm injuries, LASSO, violence intervention programs, injury recurrence, emergency department visits, time since injury, diagnosis codes, St. Louis
MeSH terms
Machine Learning, Adult, Emergency Service, Hospital, Female, Firearms, Humans, Male, Missouri, Retrospective Studies, Wounds, Gunshot

About these checks

Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.

Claims read by deepseek-v4.1-flash under definition version 3 (extract-v3) on 2026-10-27.

Classified by jev-1.13-20260917 (gold-guideline-v0.2) on 2026-10-27.

Cited sources are checked by gpt-6-sol.

Statistics and arithmetic are recomputed, not judged.

Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.

What counts as a claim ›How we measure confidence ›How we check this ›

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