The DOI matches its Crossref record; 3 of the 3 references it cites were found in a registry or an index.
Cellular signalling by lipoprotein receptors
Abstract
Lipoprotein receptors are commonly thought merely to mediate the internalization of lipoprotein particles or the exchange of lipids at the cell surface. Recent findings have now implicated these multifunctional receptors in cellular signalling mechanisms that extend beyond simple ligand endocytosis. By mediating the cellular uptake of lipophilic vitamins and hormones, megalin, a member of the LDL receptor gene family, regulates critical hormonal and metabolic processes. Other members of the LDL receptor family interact with cytoplasmic adaptor and scaffold proteins, which allows them to transmit signals directly across the plasma membrane of the target cell. This sheds a new light on the emerging roles of lipoprotein receptors in pathologic disease processes such as Alzheimer's disease.
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LDL receptor family members contain NPXY motif(s) specifically recognized by Dab2.
“The members of the LDL (low density lipoprotein) receptor family contain the NPXY motif(s) specifically recognized by Dab2”
From Endocytosis and Physiology: Insights from Disabled-2 Deficient Mice (2016) · cites this paper as Herz et al., 2000
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Cites
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Cited by
Sorted by citations
Lipoprotein receptors in the nervous system
Herz, J., & Bock, H. H. (2002) · Annual Review of Biochemistry · doi:10.1146/annurev.biochem.71.110601.135342 · Cited by 457
Self-citationApoE Deficiency Compromises the Blood Brain Barrier Especially After Injury
Methia, N., André, P., Hafezi-Moghadam, A., Economopoulos, M., Thomas, K. L., & Wagner, D. D. (2001) · Molecular Medicine · doi:10.1007/bf03401973 · Cited by 150
Marzolo, M.-P., & Bu, G. (2009) · Seminars in Cell & Developmental Biology · doi:10.1016/j.semcdb.2008.10.005 · Cited by 122
Endocytosis and Physiology: Insights from Disabled-2 Deficient Mice
Tao, W., Moore, R., Smith, E. R., & Xu, X.-X. (2016) · Frontiers in Cell and Developmental Biology · doi:10.3389/fcell.2016.00129 · Cited by 43
Metadata
- Authors
- Herz, J., Gotthardt, M., & Willnow, T. E.
- Venue
- Current Opinion in Lipidology
- Published
- 2000-04
- Volume
- 11
- Issue
- 2
- Pages
- 161-166
- ISSN
- 0957-9672
- Cited by
- 58
- References
- 3
- Language
- en
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