Cited by 188Mindfulness and Compassion InterventionsMenopause: Health Impacts and TreatmentsCancer survivorship and care

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Mindfulness training for coping with hot flashes: results of a randomized trial

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Carmody, James Francis, Crawford, Sybil, Salmoirago-Blotcher, Elena, Leung, Katherine, Churchill, Linda, Olendzki, Nicholas·2011·Menopause

DOI 10.1097/gme.0b013e318204a05cPMC PMC3123409

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Abstract

In Brief Objective: The aim of this study was to analyze the effect of participation in a mindfulness training program (mindfulness-based stress reduction, [MBSR]) on the degree of bother from hot flashes and night sweats. Methods: This study was a randomized trial of 110 late perimenopausal and early postmenopausal women experiencing an average of 5 or more moderate or severe hot flashes (including night sweats)/day. A wait-list control (WLC) was used with 3-month postintervention follow-up. The main outcome was the degree of bother from hot flashes and night sweats in the previous 24 hours. Secondary measures were hot flash intensity, quality of life, insomnia, anxiety, and perceived stress. Results: Baseline average (SD) hot flash frequency was 7.87 (3.44) and 2.81 (1.76) night sweats/day. Mean (SD) bothersomeness score was 3.18 (0.55; "moderately bothered/extremely bothered"). All analyses were intention to treat and were controlled for baseline values. Within-woman changes in bother from hot flashes differed significantly by treatment arm (week × treatment arm interaction, P = 0.042). At completion of the intervention, bother in the MBSR arm decreased on average by 14.77% versus 6.79% for WLC. At 20 weeks, total reduction in bother for MBSR was 21.62% and 10.50% for WLC. Baseline-adjusted changes in hot flash intensity did not differ between treatment arms (week × treatment arm interaction, P = 0.692). The MBSR arm made clinically significant improvements in quality of life (P = 0.022), subjective sleep quality (P = 0.009), anxiety (P = 0.005), and perceived stress (P = 0.001). Improvements were maintained 3 months postintervention. Conclusions: Our data suggest that MBSR may be a clinically significant resource in reducing the degree of bother and distress women experience from hot flashes and night sweats. The results of this study suggest that a mindfulness training program may be a clinically significant resource in reducing the degree of bother that women experience from hot flashes and night sweats. Clinically significant improvements were also found in quality of life, subjective sleep quality, anxiety, and perceived stress and were maintained for 3 months after intervention.

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Authors: Carmody, J. F., Crawford, S., Salmoirago-Blotcher, E., Leung, K., Churchill, L., & Olendzki, N.
Affiliations: University of Massachusetts Chan Medical School (US)
Corresponding author: Carmody, James Francis
ORCID: Carmody, James Francis
Crawford, Sybil
Leung, Katherine
Venue: Menopause
Publisher: Ovid Technologies (Wolters Kluwer Health)
Published: 2011-06
Volume: 18
Issue: 6
Pages: 611-620
ISSN: 1072-3714 (ISSN-L)
DOI: 10.1097/gme.0b013e318204a05c
PMC: PMC3123409
OpenAlex: W2049536230
Cited by: 188
References: 100
Citations by year: 2026: 9 · 2025: 13 · 2024: 8 · 2023: 3 · 2022: 11 · 2021: 46 · 2020: 3 · 2019: 11 · 2018: 9 · 2017: 13 · 2016: 4 · 2015: 13 · 2014: 15 · 2013: 15 · 2012: 10
FWCI: 15.50
Type: journal article
Language: en
Open access: green
www.ncbi.nlm.nih.gov
Locations: Menopause The Journal of The North American Menopause Society (publishedVersion)
PubMed (publishedVersion)
Europe PMC (PubMed Central) (acceptedVersion)
PubMed Central (acceptedVersion)
The Journal of the American Medical Association (JAMA) Network (American Medical Association) (submittedVersion)
Funders: National Center for Complementary and Integrative Health (R21AT002910)
Topics: Social Sciences › Psychology › Clinical Psychology › Mindfulness and Compassion Interventions
Health Sciences › Medicine › Endocrinology, Diabetes and Metabolism › Menopause: Health Impacts and Treatments
Health Sciences › Medicine › Oncology › Cancer survivorship and care
Keywords: mindfulness-based stress reduction, hot flashes, night sweats, menopause, perimenopause, postmenopausal women, coping, quality of life, sleep quality, anxiety, perceived stress, insomnia, waitlist control, maintenance therapy, mindfulness training
MeSH terms: Adaptation, Psychological, Female, Humans, Middle Aged, Quality of Life, Surveys and Questionnaires, Relaxation Therapy, Women's Health, Treatment Outcome, Patient Satisfaction, Meditation, Hot Flashes

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Mindfulness training for coping with hot flashes: results of a randomized trial

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