Prospects for a clinical science of mindfulness-based intervention
Open accessAbstract
Mindfulness-based interventions (MBIs) are at a pivotal point in their future development. Spurred on by an ever-increasing number of studies and breadth of clinical application, the value of such approaches may appear self-evident. We contend, however, that the public health impact of MBIs can be enhanced significantly by situating this work in a broader framework of clinical psychological science. Utilizing the National Institutes of Health stage model (Onken, Carroll, Shoham, Cuthbert, & Riddle, 2014), we map the evidence base for mindfulness-based cognitive therapy and mindfulness-based stress reduction as exemplars of MBIs. From this perspective, we suggest that important gaps in the current evidence base become apparent and, furthermore, that generating more of the same types of studies without addressing such gaps will limit the relevance and reach of these interventions. We offer a set of 7 recommendations that promote an integrated approach to core research questions, enhanced methodological quality of individual studies, and increased logical links among stages of clinical translation in order to increase the potential of MBIs to impact positively the mental health needs of individuals and communities.
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Claims the paper makes
0 of 68 cited sources checked · 0 supported · 0 flagged
- Findingnone given
The MBI field's greatest research activity has been in developing and exploring applications for new populations and target problems.
“The greatest focus of activity in the MBI field has been dedicated to the development and exploration of applications of MBIs with novel populations and target problems.”
Quote in the paperSubstantial claim - Findingown data
Most Stage I MBI studies in the mapping extended an MBI to a new problem or population.
“Most of these studies focus on extending the MBI to a novel problem or population”
Quote in the paperNot a substantial claim - Findingown data
After screening, 309 articles met inclusion criteria, comprising 118 MBCT and 191 MBSR articles.
“resulting in a total of 309 articles (MBCT n = 118, MBSR n = 191).”
Quote in the paperNot a substantial claim - Findingcitation
In nonclinical participants, MBSR showed no significant benefit on subjective well-being compared to the Health Enhancement Program.
“indicated no significant benefit associated with MBSR on subjective reports of well being”
Quote in the paperNot a substantial claim0 of 1 sources checked- cites MacCoon et al., 2012
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- Findingcitation
MBCT showed specific benefits on some outcomes compared to a relaxation control for tinnitus patients.
“specific benefits on some outcomes as compared to a relaxation control for patients with tinnitus (Philippot, Nef, Clauw, de Romree, & Segal, 2012).”
Quote in the paperSubstantial claim0 of 1 sources checked- cites Philippot, Nef, Clauw, de Romree, & Segal, 2012
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- Findingcitation
With the exception of Britton et al. (2012), few publications have reported data on adverse effects of MBIs.
“With the exception of recent work by Britton and colleagues (2012), it is notable that few publications have reported data on adverse effects of MBI.”
Quote in the paperSubstantial claim0 of 1 sources checked- cites Britton and colleagues (2012)
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- Findingcitation
In chronic pain patients, MBSR showed no significant differences on subjective reports such as pain intensity, distress, quality of life, and mood compared to a multidisciplinary pain intervention or active control/waitlist.
“Studies of MBSR among patients with chronic pain have reported no significant differences on subjective reports, such as pain intensity, distress, quality of life, and mood, as compared to a multidisciplinary pain intervention (S. Y. S. Wong et al., 2011) or active control or waitlist (Schmidt et al., 2011).”
Quote in the paperSubstantial claim0 of 2 sources checked- cites S. Y. S. Wong et al., 2011
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- cites Schmidt et al., 2011
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- Findingnone given
In contrast to the relative scarcity of Stage 0 studies, Stage I research is heavily saturated.
“In contrast to the relative paucity of Stage 0 studies, research efforts have saturated heavily Stage I.”
Quote in the paperNot a substantial claim - Findingown data
Stage II research has used randomized comparisons to WLC or TAU more than to active controls.
“such work has been conducted with a greater emphasis on randomized comparisons to WLC or TAU than to active controls.”
Quote in the paperSubstantial claim0 of 1 sources checked- cites Tables 1 and 2
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- Findingcitation
In nonclinical participants, MBSR showed some benefit on a behavioral pain task compared to the Health Enhancement Program.
“some benefit on a behavioral pain task (MacCoon et al., 2012)”
Quote in the paperNot a substantial claim0 of 1 sources checked- cites MacCoon et al., 2012
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- Findingcitation
Among patients with residual depressive symptoms, MBCT and maintenance pharmacotherapy did not differ in preventing relapse.
“The lack of differences in relapse prevention between MBCT and maintenance pharmacotherapy among patients with residual depressive symptoms”
Quote in the paperSubstantial claim0 of 1 sources checked- cites Segal et al. (2010)
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- Findingcitation
Few studies have examined measures of instructor fidelity in mindfulness-based interventions.
“few studies have examined measures of instructor fidelity (R. S. Crane et al., 2013; Segal, Teasdale, Williams, & Gemar, 2002).”
Quote in the paperSubstantial claim0 of 2 sources checked- cites R. S. Crane et al., 2013
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- cites Segal, Teasdale, Williams, & Gemar, 2002
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- Findingcitation
MBCT was superior to a pill placebo for preventing depressive relapse.
“the superiority of MBCT relative to the placebo control”
Quote in the paperSubstantial claim0 of 1 sources checked- cites Segal et al. (2010)
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- Findingcitation
MBCT was superior to psychoeducational controls for refractory depressed patients.
“MBCT demonstrated superiority to psychoeducational controls for treatment of refractory depressed patients (Chiesa, Mandelli, & Serretti, 2012)”
Quote in the paperSubstantial claim0 of 1 sources checked- cites Chiesa, Mandelli, & Serretti, 2012
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- Findingreasoning
Evidence on whether mindfulness meditation is the specific active ingredient of MBIs is equivocal.
“Although a frequent and automatic assumption is that mindfulness meditation is the “active ingredient,” findings are equivocal.”
Quote in the paperNot a substantial claim- Rests on an assumption: MBIs are multimodal interventions.
- Findingcitation
Fjorback, Arendt, et al. (2013) found MBSR vs care as usual for somatic symptom disorders had significant benefits on disability pension outcomes.
“Fjorback, Arendt, et al. (2013) also examined economic outcomes of MBSR as compared to care as usual for somatic symptom disorders, and significant benefits for MBSR were reported on disability pension outcomes.”
Quote in the paperSubstantial claim0 of 1 sources checked- cites Fjorback, Arendt, et al. (2013)
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- Findingcitation
Niles et al. (2012) conducted a feasibility test (N=33) of a mixed delivery format in which veterans with PTSD were randomized to MBSR or psychoeducation, both including two in-person and six telephone sessions.
“Similarly, (Niles et al., 2012) conducted a feasibility test (N = 33) of a mixed delivery format in which veterans with PTSD were randomized to either an MBSR intervention or a psychoeducation control, both of which included two in person and six telephone-based sessions.”
Quote in the paperSubstantial claim0 of 1 sources checked- cites Niles et al., 2012
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- Findingreasoning
It is difficult to determine from many published reports whether control participants received equivalent support for home practice.
“the degree to which participants in control conditions are provided with equivalent support for home practice is difficult to determine from many published reports”
Quote in the paperSubstantial claim- Rests on an assumption: MBSR and MBCT protocols typically include written and audio guide support for daily home practice.
- Findingcitation
Crane and Kuyken (2013) survey described barriers and facilitators to MBCT implementation across structural, political, cultural, educational, emotional, and physical/technological factors.
“Results described a range of barriers and facilitators to MBCT implementation, including structural, political, cultural, educational, emotional and physical or technological factors.”
Quote in the paperSubstantial claim0 of 1 sources checked- cites R. S. Crane and Kuyken (2013)
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- Findingreasoning
Studies on the amount of meditation practice and clinical benefit rely largely on post hoc analyses of associations between practice time or class attendance and symptom or mindfulness change.
“The studies that touch upon this question are mapped currently at Stage I because they rely largely on post hoc analyses of the association between practice time or class attendance and change in symptoms or self-reported mindfulness skill.”
Quote in the paperSubstantial claim - Findingown data
Only two reviewed studies approached Stage III criteria.
“Of the studies we reviewed, only two were identified that approached the criteria for Stage III.”
Quote in the paperSubstantial claim - Findingcitation
In nonclinical participants, MBSR showed benefit on biological indices of stress-provoked inflammatory response compared to the Health Enhancement Program.
“benefit on biological indices of stress provoked inflammatory response (Rosenkranz et al., 2013).”
Quote in the paperNot a substantial claim0 of 1 sources checked- cites Rosenkranz et al., 2013
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- Findingcitation
Lab et al. (2012) examined employee preferences for MBCT delivery formats.
“Lab and colleagues (2012) examined preferences of employees from large healthcare organizations for MBCT targeting depression relapse prevention delivered by in-person group, online group, in-person individual, and telephone-based individual format.”
Quote in the paperNot a substantial claim0 of 1 sources checked- cites Lab and colleagues (2012)
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- Findingcitation
The field is becoming more programmatic by anchoring clinical intervention in basic research and testing mechanisms of change.
“we find indicators that the field is becoming more programmatic in its approach by anchoring clinical intervention in basic research that specifies clear targets of intervention and by testing proposed mechanisms of change.”
Quote in the paperSubstantial claim - Findingcitation
Williams et al. (2014) found no difference in relapse rates over 1-year among MBCT, TAU, and cognitive psychoeducation.
“The results indicated no difference in relapse rates over a 1-year follow-up among the three groups”
Quote in the paperSubstantial claim0 of 1 sources checked- cites J. M. G. Williams et al. (2014)
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- Findingcitation
Garland et al. (2014) tested clinical outcomes and mediators of mindfulness-oriented recovery enhancement for chronic pain and opioid misuse in a Stage II RCT with active control.
“Garland and colleagues (2014) tested both clinical outcomes and mediators of an MBI developed specifically for chronic pain and prescription opioid misuse (mindfulness-oriented recovery enhancement) in the context of a Stage II randomized clinical trial with an active control (supportive group therapy).”
Quote in the paperSubstantial claim0 of 1 sources checked- cites Garland and colleagues (2014)
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- Findingcitation
Even comprehensive active controls such as the Health Enhancement Program use different teachers for each module, unlike MBSR or MBCT where the same teacher guides all eight sessions.
“Even comprehensive active controls such as the Health Enhancement Program introduce different teachers for each module of the curriculum, unlike MBSR or MBCT in which the same teacher guides the group for the entire eight sessions (MacCoon et al., 2012).”
Quote in the paperSubstantial claim0 of 1 sources checked- cites MacCoon et al., 2012
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- Findingcitation
Patten and Meadows (2009) used Canadian Community Health Survey data to model population density needed for sustained in-person MBCT delivery.
“Patten and Meadows (2009) examined data were from the Canadian Community Health Survey to construct a simulation model that estimated population density required to support sustained delivery of in-person MBCT.”
Quote in the paperSubstantial claim0 of 1 sources checked- cites Patten and Meadows (2009)
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- Findingcitation
As interventions are scaled up for dissemination or delivered by successive generations, outcomes suffer.
“As interventions are “scaled up” for dissemination in community settings or are delivered in successive generations following the original intervention developer, outcomes suffer.”
Quote in the paperSubstantial claim0 of 1 sources checked- cites Weisz, Ng, and Bearman (2014)
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- Findingcitation
Findings on the association between amount of practice and clinical outcomes are mixed, with some studies supporting and others not.
“Findings are mixed, with some studies supporting an association between amount of practice and clinical outcomes”
Quote in the paperSubstantial claim0 of 3 sources checked- cites Beddoe & Murphy, 2004
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- cites Carmody & Baer, 2008
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- cites Carlson, Speca, Patel, & Goodey, 2004
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- Findingcitation
More studies are incorporating active control conditions to address specific efficacy.
“more studies are incorporating active control conditions that can help to address questions of specific efficacy.”
Quote in the paperNot a substantial claim - Findingcitation
Only three studies, two purely descriptive, addressed dissemination or broad implementation of MBI as a primary aim.
“Only three studies, two of which are purely descriptive, addressed as a primary aim questions relevant to the dissemination or broad implementation of MBI.”
Quote in the paperSubstantial claim - Findingreasoning
Few active controls have been truly matched to MBSR or MBCT on all components except mindfulness.
“few active controls have been truly matched to MBSR or MBCT on all components except the mindfulness.”
Quote in the paperSubstantial claim- Rests on an assumption: MBSR and MBCT protocols typically include written and audio guide support for daily home practice.
- Findingcitation
Bowen et al. (2014) tested mindfulness-based relapse prevention for substance abuse in an RCT vs cognitive behavioral relapse prevention and TAU.
“The work of Bowen et al. (2014) provides an excellent example of rigorous movement toward Stage III research in which the MBI developed for preventing relapse in substance abuse disorders (mindfulness-based relapse prevention) was tested in a randomized clinical trial with comparison to an active control (cognitive behavioral relapse prevention) and TAU.”
Quote in the paperSubstantial claim0 of 1 sources checked- cites Bowen et al. (2014)
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- Findingcitation
Kuyken et al. (2015) found relapse rates statistically equivalent in MBCT and maintenance antidepressant medication for recurrent depression.
“Findings from Kuyken et al. (2015) indicate that relapse rates are statistically equivalent in MBCT and maintenance antidepressant medication, the current standard of care for recurrent depression.”
Quote in the paperSubstantial claim0 of 1 sources checked- cites Kuyken et al. (2015)
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- Findingcitation
In Williams et al. subgroup analysis, patients with childhood trauma histories showed significant benefit for MBCT.
“A subgroup analysis of patients with histories of childhood trauma, however, indicated significant benefit for MBCT.”
Quote in the paperSubstantial claim0 of 1 sources checked- cites J. M. G. Williams et al. (2014)
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- Findingcitation
Bowen et al. study was a hybrid of Stage II and III because research clinicians delivered the 8-week intervention in community chemical dependency treatment facilities.
“This study represented a hybrid of Stage II and III research because research clinicians delivered the 8-week intervention in community chemical dependency treatment facilities.”
Quote in the paperNot a substantial claim0 of 1 sources checked- cites Bowen et al. (2014)
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- Premisecitation
The first use of mindfulness meditation to prevent depression was grounded in basic research on depressive relapse.
“the first application of mindfulness meditation for the prevention of depression was rooted in basic research on the nature of depressive relapse.”
Quote in the paperNot a substantial claim - Premisecitation
Multiple meta-analyses of MBSR and MBCT trials have generally convergent findings.
“Multiple meta-analytic studies including MBSR and MBCT trials have been published in recent years (Goyal et al., 2014; Hofmann, Sawyer, Witt, & Oh, 2010; Piet & Hougaard, 2011), with generally convergent findings.”
Quote in the paperSubstantial claim0 of 3 sources checked- cites Goyal et al., 2014
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- cites Hofmann, Sawyer, Witt, & Oh, 2010
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- cites Piet & Hougaard, 2011
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- Interpretationreasoning
If attention continues to favor expanding applications over deepening the evidence base, the public health impact of MBIs may be limited.
“If the weight of clinical and scientific attention remains devoted to increasing the range of applications rather than the depth of the evidence base, public health impact may be limited.”
Quote in the paperSubstantial claim - Interpretationreasoning
Placing MBI research within a broader clinical psychological science framework can substantially increase its public health impact.
“We contend, however, that the public health impact of mindfulness-based interventions can be enhanced significantly by situating this work in a broader framework of clinical psychological science.”
Quote in the paperNot a substantial claim - Premisecitation
Greater access to depressive cognition prospectively predicted relapse risk.
“studies suggested that such increased access prospectively predicted relapse risk (Segal et al., 2006).”
Quote in the paperSubstantial claim0 of 1 sources checked- cites Segal et al., 2006
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- Interpretationreasoning
If more studies of the same kinds are produced without addressing the identified gaps, the relevance and reach of MBIs will be limited.
“generating more of the same types of studies without addressing such gaps will limit the relevance and reach of these interventions.”
Quote in the paperNot a substantial claim - Interpretationreasoning
Mapping the MBI evidence base through the NIH stage model reveals important gaps in the current evidence.
“From this perspective, we suggest that important gaps in the current evidence base become apparent”
Quote in the paperSubstantial claim - Interpretationcitation
The work that identified a target, population, and rationale for mindfulness meditation in depression prevention was based on basic research.
“This work identified a potential target for intervention (i.e., ruminative emotion linked cognitive processes), a population for whom this target was relevant and identifiable (i.e., individuals with histories of recurrent depression), and a logical basis for the application of mindfulness meditation”
Quote in the paperNot a substantial claim - Interpretationcitation
The superiority of MBCT over placebo suggests its benefits are specific to MBCT components rather than common clinical care factors.
“suggested that such benefits are specific to components of MBCT rather than factors common to clinical care”
Quote in the paperSubstantial claim0 of 1 sources checked- cites Segal et al. (2010)
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- Interpretationreasoning
A failed individual trial in which the MBI does not outperform the comparator may be a success for advancing the field broadly.
“a “failed” individual trial in which the MBI does not outperform the comparator intervention may be a “success” when viewing the advancement of the field broadly.”
Quote in the paperNot a substantial claim - Interpretationreasoning
Non-randomized and mostly uncontrolled Stage I studies support excitement about using MBIs in clinical settings across many target populations and problems.
“The non-randomized and, most often, uncontrolled studies, mapped here at Stage I, clearly support valid excitement about the use of MBI in clinical settings across a wide range of target populations and problems.”
Quote in the paperSubstantial claim - Premisecitation
MBCT studies suggest that effects may be moderated by vulnerability factors including more recurrent depressive episodes and residual depressive symptoms.
“studies of MBCT suggest that effects may be moderated by vulnerability factors, including more recurrent depressive episode histories (Ma & Teasdale, 2004; Teasdale et al., 2000) and residual depressive symptoms (Segal et al., 2010).”
Quote in the paperSubstantial claim0 of 3 sources checked- cites Ma & Teasdale, 2004
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- cites Teasdale et al., 2000
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- cites Segal et al., 2010
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- Interpretationcitation
The lack of formal measures, methods, and standards for instructor quality may originate in core guiding principles about how MBI is best delivered.
“The lack of attention to developing formal measures, methods, and standards for determining instructor quality may have its roots in core guiding principles about how MBI is best delivered.”
Quote in the paperNot a substantial claim0 of 1 sources checked- cites Kabat-Zinn
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- Premisecitation
Craigie et al. (2008) found relatively poor performance of MBCT in an open trial compared with CBT benchmarks in other studies of generalized anxiety disorder.
“An instructive example is provided by Craigie, Rees, Marsh, and Nathan (2008) regarding the relatively poor performance of MBCT in an open trial when compared to benchmarks of cognitive behavioral therapy in other studies targeting generalized anxiety disorder.”
Quote in the paperNot a substantial claim0 of 1 sources checked- cites Craigie, Rees, Marsh, and Nathan (2008)
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- Study design and conductreasoning
The Segal et al. comparison did not control for time with clinicians, group support, and home practice.
“this comparison did not control for other relevant dimensions such as time with clinicians, group support, and completing home practices.”
Quote in the paperSubstantial claim0 of 1 sources checked- cites Segal et al. (2010)
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- Premisereasoning
MBCT and MBSR were selected as target interventions because each has enough empirical record to enable mapping.
“We focus, however, on MBCT and MBSR as the target interventions for this review because each has amassed a sufficient empirical record to enable mapping of this nature.”
Quote in the paperSubstantial claim - Interpretationreasoning
A glance at the range of problems for which MBIs are applied suggests possible vulnerability in linking basic and intervention research.
“A glance at the range of problems for which MBIs are being applied suggests possible vulnerability in this regard.”
Quote in the paperSubstantial claim - Premisecitation
At best only one in three people with mental health problems receive minimally adequate treatment.
“Current estimates suggest that, at best, only one in three people who struggle with mental health problems will receive “at least minimally adequate treatment” (Wang et al., 2005).”
Quote in the paperNot a substantial claim0 of 1 sources checked- cites Wang et al., 2005
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- Interpretationcitation
Implementation of group-based in-person MBCT may be challenging in small population centers.
“Results suggested that implementation of such group-based in-person approaches may be challenging in small population centers.”
Quote in the paperSubstantial claim0 of 1 sources checked- cites Patten and Meadows (2009)
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- Interpretationcitation
The Williams et al. finding challenges the specific efficacy of the mindfulness meditation component of MBCT.
“a finding that challenges the specific efficacy of the mindfulness meditation component of MBCT.”
Quote in the paperSubstantial claim0 of 1 sources checked- cites J. M. G. Williams et al. (2014)
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- Premisereasoning
Care-as-usual comparisons in healthcare settings allow determining whether MBI adds incremental benefit to available care.
“Care-as-usual comparisons, particularly in the context of healthcare settings in which such care can be precisely described, allow us to determine whether MBI add incremental benefit to what is available.”
Quote in the paperSubstantial claim - Interpretationreasoning
Saturation of studies at Stage I and II using WLC/TAU controls and paucity at later stages highlights risk of neglecting promising interventions as orphans.
“the saturation of studies at Stage I and Stage II using WLC or TAU controls, and the relative paucity of studies at later stages, highlights the risk of neglecting promising interventions as “orphans” early in the research process.”
Quote in the paperSubstantial claim - Interpretationcitation
Bowen et al. advanced by implementing in a specific healthcare setting that allowed TAU to be clearly defined and measured.
“this study represents an advance by implementing the study in the context of a specific healthcare setting that allowed, TAU to be clearly defined and measured.”
Quote in the paperSubstantial claim0 of 1 sources checked- cites Bowen et al. (2014)
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- Interpretationreasoning
MBCT may show specific benefit for more vulnerable individuals.
“It is possible that MBCT may show specific benefit for more vulnerable individuals, as was the case in the original studies that examined differences by number of prior episodes (Ma & Teasdale, 2004; Teasdale et al., 2000).”
Quote in the paperSubstantial claim0 of 2 sources checked- cites Ma & Teasdale, 2004
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- cites Teasdale et al., 2000
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- Classified as probably not a substantial claim. 31
- May combine two claims. 26
Probably not a substantial claim: may not pass S3 (load-bearing).
Findingown dataThe initial database search returned 3,217 articles.
“yielding 3,217 articles in the initial search.”
Quote in the paperNot a substantial claimMay combine two claims.
Findingown dataOnly a small number of MBI studies have examined candidate mediators or moderators, and even fewer have formally tested mediation or used methods for personalized treatment selection.
“our mapping indicates that only a small number of studies have explored candidate mediators or moderators of outcome; and of these, even fewer have tested mediation formally or incorporated recent methods that move the field closer to a personalized medicine framework”
Quote in the paperSubstantial claimProbably not a substantial claim: may not pass S3 (load-bearing).
FindingreasoningThe mapping at Stage I mainly includes feasibility and pilot testing studies, including nonrandomized open-trial designs.
“Our mapping at this stage includes mainly feasibility and pilot testing studies including nonrandomized open-trial designs of an MBI”
Quote in the paperNot a substantial claimMay combine two claims.
FindingcitationMBCT showed no significant benefit compared to an educational control for caregivers of dementia patients, though both active treatments outperformed a respite-only control.
“MBCT showed no significant benefit as compared to an educational control for caregivers of dementia patients, although both active treatments outperformed a respite only control (Oken et al., 2010).”
Quote in the paperSubstantial claim0 of 1 sources checked- cites Oken et al., 2010
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May combine two claims.
FindingcitationThe field has given little scientific attention to operationalizing MBI instructor training requirements and developing scaffolding resources for instructors.
“Operationalizing this requirement and developing scaffolding resources for instructors learning MBI are gaps that exist currently at Stage I.”
Quote in the paperSubstantial claim- Rests on an assumption: MBI instructors are expected to have personal mindfulness meditation practice in addition to professional clinical training.
May combine two claims.
FindingcitationMBSR studies often fail to outperform active controls on primary outcomes but show mixed results on secondary outcomes.
“Studies of MBSR provide similarly complex findings, reporting failure to outperform an active control on primary outcomes but often mixed results on secondary outcomes.”
Quote in the paperSubstantial claimMay combine two claims.
Findingnone givenAmong MBCT-targeted problems, only depression and comorbid health and mental health conditions, and among MBSR studies primarily cancer, show incremental progression from Stage I to later stages.
“Among problems targeted by MBCT, only work on depression and comorbid health and mental health conditions, and within MBSR studies, primarily work with patients with cancer, show incremental progression from Stage I to subsequent stages.”
Quote in the paperNot a substantial claimProbably not a substantial claim: may not pass S3 (load-bearing).
FindingreasoningThe mapping identified studies that integrate basic research methods into later-stage intervention studies, marked with asterisks.
“Studies identified with asterisks in Stages I–V provide examples of movement to such integration.”
Quote in the paperNot a substantial claimMay combine two claims.
FindingreasoningThe included studies vary in methodological rigor but share a goal of understanding whether an MBI works beyond symptom report and how and for whom.
“These studies encompass varying degrees of methodological rigor; however, they share the common element of seeking to understand whether an MBI works beyond simply symptom report as well as how and for whom.”
Quote in the paperNot a substantial claimMay combine two claims.
FindingcitationIn generalized anxiety disorder, MBSR showed no superiority over stress management education on primary anxiety symptom severity but had advantage on secondary anxiety outcomes.
“A comparison of MBSR and stress management education among patients with generalized anxiety disorder also found no evidence of superiority for MBSR on the primary outcome of anxiety symptom severity, but reported advantage on secondary anxiety outcomes (Hoge et al., 2013).”
Quote in the paperSubstantial claim0 of 1 sources checked- cites Hoge et al., 2013
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May combine two claims.
FindingcitationKuyken et al. (2008) found MBCT comparable to maintenance pharmacotherapy for relapse prevention and cost-effectiveness in primary care, with advantages on residual depressive symptoms, psychiatric comorbidity, and quality of life.
“Kuyken et al. (2008) examined the effects of MBCT as compared to maintenance pharmacotherapy among patients treated in primary care, with results suggesting comparable relapse prevention and cost effectiveness as well as advantage to MBCT on indices of reducing residual depressive symptoms, psychiatric comorbidity, and quality of life.”
Quote in the paperSubstantial claim0 of 1 sources checked- cites Kuyken et al. (2008)
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May combine two claims.
FindingcitationThompson et al. (2010) compared distance delivery of MBCT via telephone or internet for epilepsy and depressive symptoms (N=40) to WLC, co-facilitated by a layperson with epilepsy and an MPH student.
“N. J. Thompson et al. (2010) compared “distance delivery” of MBCT via telephone or internet for patients with epilepsy and depressive symptoms (N = 40), as compared to WLC, and the intervention was co-facilitated by a layperson with epilepsy and a master's of public health student.”
Quote in the paperSubstantial claim0 of 1 sources checked- cites N. J. Thompson et al. (2010)
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May combine two claims.
FindingcitationA recent meta-analysis reported small to moderate effects and little evidence of specific efficacy for meditation.
“a recent meta-analysis of the clinical applications of meditation (Goyal et al., 2014), which reported small to moderate effects and little evidence of specific efficacy.”
Quote in the paperSubstantial claim0 of 1 sources checked- cites Goyal et al., 2014
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May combine two claims.
Findingnone givenOnly two MBCT trials and one MBSR trial published before 2014 addressed effectiveness, with two focused on economic outcomes.
“Only two trials of MBCT and one of MBSR were published prior to 2014 that addressed questions of effectiveness, with two focused specifically on economic outcomes.”
Quote in the paperSubstantial claimMay combine two claims.
Findingnone givenFew studies have tested whether instructors find the interventions they deliver credible, raising the possibility of allegiance effects.
“few studies have tested the degree to which instructors find the interventions they are delivering to be credible, thus introducing the possibility of allegiance effects”
Quote in the paperSubstantial claimMay combine two claims.
Findingcitationvan Ravesteijn et al. (2013) found MBCT vs TAU for persistent medically unexplained symptoms had lower hospital costs and higher mental health care costs.
“van Ravesteijn, Lucassen, Bor, van Weel, and Speckens (2013) examined the cost-effectiveness of MBCT compared with TAU among patients with persistent medically unexplained symptoms, with results indicating lower hospital costs and higher mental health care costs among patients receiving MBCT.”
Quote in the paperNot a substantial claim0 of 1 sources checked- cites van Ravesteijn, Lucassen, Bor, van Weel, and Speckens (2013)
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Classified as probably not a substantial claim.
FindingreasoningLack of attention to Stage V work is a serious gap in developing a clinical science of MBI.
“The lack of attention to Stage V work is a serious gap in an effort to develop a clinical science of MBI.”
Quote in the paperSubstantial claimProbably not a substantial claim: may not pass S4 (based).
Findingnone givenStage III has been underemphasized in MBI studies.
“Stage III has been underemphasized in studies of MBI (and clinical psychological science generally).”
Quote in the paperNot a substantial claimMay combine two claims.
FindingcitationSome active controls match frequency and duration of sessions, while others involve shorter sessions.
“although some active controls carefully match the frequency and duration of sessions (e.g., Philippot et al., 2012), others are structurally different, involving shorter sessions (e.g., Y. W. Kim et al., 2009).”
Quote in the paperNot a substantial claim0 of 2 sources checked- cites Philippot et al., 2012
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- cites Y. W. Kim et al., 2009
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Probably not a substantial claim: may not pass S3 (load-bearing), S4 (based).
Findingnone givenThe last decade saw an exponential increase in the number of MBI studies and the breadth of clinical problems and populations targeted.
“The last decade has witnessed an exponential rate of increase in the number of studies and the breadth of clinical problems and populations targeted.”
Quote in the paperNot a substantial claimMay combine two claims.
PremisecitationIn Vøllestad et al. (2011), mindfulness statistically mediated anxiety symptom changes after MBSR, but the analysis did not demonstrate true mediation because temporal precedence was absent.
“Vøllestad, Sivertsen, and Nielsen (2011) who describe a well-conceived analysis in which mindfulness statistically mediated changes in anxiety symptoms following MBSR, but owing to the absence of temporal precedence for these changes did not demonstrate true mediation.”
Quote in the paperNot a substantial claim0 of 1 sources checked- cites Vøllestad, Sivertsen, and Nielsen (2011)
Not checked in the free run.
Probably not a substantial claim: may not pass S3 (load-bearing).
Premisenone givenMBSR and MBCT are distinguished from other related interventions by their predominant focus on mindfulness meditation, eight-week structure, daily home practice, and instructor training requirements.
“MBSR and MBCT are distinguished by the predominant focus on mindfulness meditation practices, the 8-week course structure, active daily home practice of mindfulness meditation and the role and training requirements of the instructor.”
Quote in the paperNot a substantial claimProbably not a substantial claim: may not pass S2 (checkable).
InterpretationreasoningFailure to specify clear intervention targets and mediating processes may reduce the public health impact of MBI research.
“failure to attend to the “basics” may undermine the potential public health impact of research on MBIs.”
Quote in the paperNot a substantial claimMay combine two claims.
PremisecitationThe overall consensus of these meta-analyses is that MBIs work, although many individual studies have methodological quality problems.
“although most have emphasized problems with the methodological quality of many individual studies, the overall consensus appears to be “yes.” We concur with these interpretations”
Quote in the paperSubstantial claimMay combine two claims.
PremisecitationFormerly depressed patients showed larger increases in depressogenic thinking styles after a sad mood induction than healthy controls, suggesting that a depression history is linked to greater access to depressive cognition during mild sad mood.
“formerly depressed patients showed greater increases in depressogenic thinking styles, suggesting that a history of depression was associated with increased access to depressive cognition in the context of mild sad mood (Teasdale, 1988).”
Quote in the paperSubstantial claim0 of 1 sources checked- cites Teasdale, 1988
Not checked in the free run.
May combine two claims.
InterpretationreasoningAlthough intervention studies suggest MBCT has promise for these patients, basic research supporting a rationale for why is often lacking.
“Although intervention studies suggest that MBCT has promise for such patients, the basic research necessary to support a rationale for “why” is often lacking”
Quote in the paperSubstantial claimProbably not a substantial claim: may not pass S3 (load-bearing).
PremisecitationMBCT was developed by Segal, Williams, and Teasdale by extending MBSR and integrating it with cognitive-behavioral therapy.
“Segal, Williams and Teasdale (2012) built upon this early foundation with the development of MBCT, extending and integrating the framework and practices of MBSR with cognitive-behavioral therapy.”
Quote in the paperNot a substantial claim0 of 1 sources checked- cites Segal, Williams and Teasdale (2012)
Not checked in the free run.
Probably not a substantial claim: may not pass S3 (load-bearing).
PremisecitationMBSR originated with Jon Kabat-Zinn and colleagues in 1979 at the University of Massachusetts Medical Center.
“MBSR originated in the work of Jon Kabat Zinn and colleagues in 1979 at the University of Massachusetts Medical Center (Kabat-Zinn, 1990).”
Quote in the paperNot a substantial claim0 of 1 sources checked- cites Kabat-Zinn, 1990
Not checked in the free run.
Probably not a substantial claim: may not pass S2 (checkable).
InterpretationreasoningThe rapid growth of new potential indications for MBIs risks neglecting the link between Stage 0 and later stages.
“The rapid proliferation of new potential indications for MBIs risks neglecting the link between Stage 0 and subsequent stages.”
Quote in the paperNot a substantial claimProbably not a substantial claim: may not pass S2 (checkable). May combine two claims.
InterpretationreasoningThe field risks failing to advance if Stage I research is treated as sufficient to proceed to broad dissemination and implementation, or if it stalls by accumulating more Stage I studies.
“This excitement, however, must be tempered, given the risk that the field will fail to advance if Stage I research is seen as a sufficient “green light” to proceed to broad dissemination and implementation of MBI, or if the field “stalls out” by simply amassing more studies at Stage I.”
Quote in the paperNot a substantial claimProbably not a substantial claim: may not pass S2 (checkable).
InterpretationreasoningThere are indications that some stages and links between stages warrant greater attention.
“there are indications that some stages and the links between stages warrant greater attention.”
Quote in the paperNot a substantial claimClassified as probably not a substantial claim.
Premisenone givenThe NIH stage model does not specify a direct pathway from Stage I to Stages IV or V.
“the NIH stage model underscores the value of the full cycle of research stages, and notably does not specify a direct pathway from Stage I to Stages IV or V.”
Quote in the paperSubstantial claimProbably not a substantial claim: may not pass S2 (checkable).
InterpretationreasoningExtending MBSR, MBCT, and other MBIs to new populations and conditions may require modifications and tailoring to address salient pathogenic mechanisms.
“extensions of MBSR, MBCT, and other MBIs to new populations and conditions may require modifications and tailoring to address their salient pathogenic mechanisms”
Quote in the paperNot a substantial claimProbably not a substantial claim: may not pass S2 (checkable). May combine two claims.
InterpretationreasoningA large number of promising uncontrolled studies cannot substitute for later-stage studies, and researchers, practitioners, and the public should not mistake many Stage I studies for evidence of efficacy or effectiveness.
“The sheer quantity of promising uncontrolled studies cannot substitute for later stage studies; researchers, practitioners, and the public must be cautious not to conflate a lot of studies at Stage I with indications of efficacy or effectiveness.”
Quote in the paperNot a substantial claimClassified as probably not a substantial claim.
PremisecitationLack of clear attention to boundary conditions and scientific plausibility is often cited as a hallmark of pseudoscience.
“Absence of clear attention to both “boundary conditions” and “scientific plausibility” is often cited as hallmarks of pseudoscience (Lilienfeld, 2003).”
Quote in the paperSubstantial claim0 of 1 sources checked- cites Lilienfeld, 2003
Not checked in the free run.
Probably not a substantial claim: may not pass S2 (checkable). May combine two claims.
InterpretationreasoningSuch failed findings help inform boundary conditions and strengthen the pathway between Stage I and Stage 0.
“Such findings help to inform the “boundary conditions” necessary for scientific progress and strengthen the pathway between Stage I and Stage 0”
Quote in the paperNot a substantial claimMay combine two claims.
PremisecitationMany basic research studies have examined correlates of mindfulness meditation and offer methods or proxy markers for integration into applied trials.
“Many basic research studies have investigated correlates of mindfulness meditation (see Lutz et al., 2015) and provide methods or proxy markers to consider for integration in applied trials.”
Quote in the paperSubstantial claim0 of 1 sources checked- cites Lutz et al., 2015
Not checked in the free run.
Classified as probably not a substantial claim. May combine two claims.
InterpretationreasoningThe authors view randomized controlled trials as having specific methodological value for future MBI research and therefore mapped all nonrandomized designs at Stage I.
“we view the methodological rigor of randomized controlled trials as of specific value for the future of research on MBI; thus, we map all nonrandomized designs at Stage I.”
Quote in the paperSubstantial claimClassified as probably not a substantial claim.
InterpretationcitationCraigie et al.'s findings raise valuable questions for Stage 0 about potential maintaining factors in generalized anxiety disorder.
“They highlight valuable questions that can be “sent back” to Stage 0 about potential maintaining factors in generalized anxiety disorder.”
Quote in the paperSubstantial claimMay combine two claims.
InterpretationreasoningRandomized designs with intervention controls allow valid causal inference about whether an MBI has an effect but not about what specifically drives that effect.
“Such designs permit valid inference about whether the MBI produces an effect on the measured outcome but not about what, specifically, is driving the effect.”
Quote in the paperSubstantial claim- Rests on an assumption: MBIs are multimodal interventions.
Probably not a substantial claim: may not pass S2 (checkable).
InterpretationcitationUnderemphasizing basic-research links and precise specification of for whom and how treatment works risks making MBI study appear less scientific and more pseudoscientific.
“Underemphasizing links to basic research and precise specification of for whom and how a treatment works risks situating the study of MBI less as science and more as pseudoscience”
Quote in the paperNot a substantial claimMay combine two claims.
PremisecitationIn Arch and Ayers (2013), anxiety-disorder patients were randomized to MBSR or CBT, and treatment response depended partly on baseline depressive symptom severity comorbidity and anxiety sensitivity.
“Arch and Ayers (2013) provide another instructive example, in which patients with anxiety disorders were randomized to MBSR or cognitive behavioral therapy, with results indicating the response to intervention depended in part on baseline depressive symptom severity comorbidity and anxiety sensitivity.”
Quote in the paperSubstantial claim0 of 1 sources checked- cites Arch and Ayers (2013)
Not checked in the free run.
Probably not a substantial claim: may not pass S3 (load-bearing).
Premisenone givenThe NIH stage model is proposed as overlapping and mutually informing points along a continuum rather than fixed linear steps.
“The NIH stage model is proposed not as a fixed and linear set of steps to take in chronological order, but rather as a set of overlapping and mutually informing points along a continuum of research.”
Quote in the paperNot a substantial claimProbably not a substantial claim: may not pass S3 (load-bearing).
PremisecitationWeisz, Ng, and Bearman (2014) describe implementation cliff as voltage drop when interventions move through clinical science process.
“Weisz, Ng, and Bearman (2014) refer to the “implementation cliff” to describe the “voltage drop” that often occurs as interventions move through the clinical science process.”
Quote in the paperNot a substantial claim0 of 1 sources checked- cites Weisz, Ng, and Bearman (2014)
Not checked in the free run.
Classified as probably not a substantial claim.
InterpretationreasoningRelative lack of attention to studying broadly implementable instructor training may make MBI vulnerable to implementation cliff and limbo.
“the relative lack of attention to studying methods of training instructors that can be broadly implemented may make MBI approaches vulnerable to both the implementation cliff and limbo.”
Quote in the paperSubstantial claim- Rests on an assumption: MBI instructors are expected to have personal mindfulness meditation practice in addition to professional clinical training.
Probably not a substantial claim: may not pass S3 (load-bearing).
Study design and conductreasoningThe classification of those two studies as Stage III is arguable due to their pilot nature and hybrid use of community and research clinicians.
“This classification is arguable given the pilot nature of the work and the hybrid use of community and research clinicians”
Quote in the paperNot a substantial claimProbably not a substantial claim: may not pass S3 (load-bearing).
PremisecitationRecent discussions focus on disruptive innovation to increase reach and access of MBI.
“Recent discussions have focused, in particular, on the model of “disruptive innovation” in which new technologies may be integrated in the service of increasing reach and access of MBI.”
Quote in the paperNot a substantial claim0 of 2 sources checked- cites Kazdin & Blase, 2011
Not checked in the free run.
- cites Rotheram-Borus, Swendeman, & Chorpita, 2012
Not checked in the free run.
Probably not a substantial claim: may not pass S3 (load-bearing).
PremisecitationWeisz (2014) describes implementation limbo where resource constraints lower training provider bar.
“Weisz (2014) also describe the problem of “implementation limbo” in which resource constraints set the “bar” for training providers at ever lower levels”
Quote in the paperNot a substantial claim0 of 1 sources checked- cites Weisz (2014)
Not checked in the free run.
Classified as probably not a substantial claim.
PremisecitationEvans and Clarke (2011) describe orphan innovations as effort dedicated to design and initial testing but little care to spreading intervention to contexts of need.
“Evans and Clarke (2011) describe the problem of “orphan innovations,” in which effort is dedicated to the design and initial testing of an intervention but little care is allocated to the task of spreading the intervention to contexts of need.”
Quote in the paperSubstantial claim0 of 1 sources checked- cites Evans and Clarke (2011)
Not checked in the free run.
Probably not a substantial claim: may not pass S3 (load-bearing). May combine two claims.
PremisecitationRecommendations in psychotherapy include novel delivery formats such as self-management, brief adaptations, technology-driven delivery, and integration into healthcare packages.
“Recommendations within general psychotherapy domains have included the examination of novel delivery formats such as self-management and self-help formats, brief or more parsimonious adaptations, technology and media driven delivery formats, and integration within broader healthcare packages (Kazdin & Blase, 2011; Rotheram-Borus, Swendeman, & Chorpita, 2012).”
Quote in the paperNot a substantial claim0 of 2 sources checked- cites Kazdin & Blase, 2011
Not checked in the free run.
- cites Rotheram-Borus, Swendeman, & Chorpita, 2012
Not checked in the free run.
Probably not a substantial claim: may not pass S2 (checkable).
InterpretationreasoningSituating MBI work in clinical psychological science highlights important lessons and gaps in the current evidence base.
“Doing so highlights important lessons and gaps in our current evidence base.”
Quote in the paperNot a substantial claimProbably not a substantial claim: may not pass S2 (checkable).
InterpretationreasoningThe public health impact of MBI work is likely enhanced by situating it in a broader clinical psychological science framework.
“We contend that the public health impact of this work is likely to be enhanced by situating work on MBI in a broader framework of clinical psychological science.”
Quote in the paperNot a substantial claim
The paper relies on this without support.
MBI instructors are expected to have personal mindfulness meditation practice in addition to professional clinical training.
“which require a personal practice in mindfulness meditation in addition to professional training in the clinical approach”
The paper relies on this without support.
MBIs are multimodal interventions.
“MBIs are multimodal interventions.”
The paper relies on this without support.
MBSR and MBCT protocols typically include written and audio guide support for daily home practice.
“MBSR and MBCT protocols typically include written and audio guide support for daily home practice”
Claims other papers make about this one
Each is checked against this paper’s own text: does it say what the citing paper says it does?
A relatively low-cost mobile application can be widely disseminated and may increase treatment access and utilization, especially among underserved populations.
“Accessibility is an important area of future study: a relatively low-cost mobile application can be widely disseminated and may increase treatment access and utilization especially among underserved populations (44–46).”
From Targeting Anxiety to Improve Sleep Disturbance: A Randomized Clinical Trial of App-Based Mindfulness Training. (2022) · cites this paper as [45]
Recommendation 7 (page unavailable) says new technologies may increase the reach and access of mindfulness-based interventions and that technology-driven formats may aid dissemination. It does not specifically address a low-cost mobile application, increased treatment utilization, or benefits especially for underserved populations. (LLM, conf=0.84)
Experimental — accuracy not yet measuredPsychological theory and research now guides the development of many MBPs.
“Psychological theory and research now guides the development of many MBPs (Dimidjian & Segal, 2015).”
From What defines mindfulness-based programs? The warp and the weft (2017) · cites this paper as Dimidjian & Segal, 2015
In “Indications of Promise” (page not provided), the paper says the field is beginning to anchor interventions in basic research and gives a recent example. But Recommendation 1 says newer applications have less frequently identified their intended targets and often lack the basic research needed to explain why they should work. The paper therefore supports an emerging trend, not the claim that psychological theory and research already guide the development of many MBPs. (LLM, conf=0.85)
Experimental — accuracy not yet measuredManualized group settings incorporate many components contributing to their observed clinical benefits.
“These settings incorporate many components contributing to their observed clinical benefits [46–49].”
From Emotion Regulation as a Mechanism of Mindfulness in Individual Cognitive-Behavioral Therapy for Depression and Anxiety Disorders (2024) · cites this paper as [46]
Recommendation 4 describes mindfulness-based interventions as multimodal and identifies group support, clinician time, and home practice as components that could affect outcomes (page not available in our copy). It also says the evidence does not establish which components drive the observed benefits, so the claim overstates their contribution as settled. (LLM, conf=0.84)
Experimental — accuracy not yet measuredA significant gap persists in understanding the effects of mindfulness interventions on therapeutic outcomes when embedded in individual CBT sessions.
“a significant gap persists in understanding the effects of mindfulness interventions on therapeutic outcomes when embedded in individual CBT sessions [46, 49, 51].”
From Emotion Regulation as a Mechanism of Mindfulness in Individual Cognitive-Behavioral Therapy for Depression and Anxiety Disorders (2024) · cites this paper as [46]
Recommendation 4 says existing studies often cannot determine which components of mindfulness-based interventions drive outcomes, supporting a general research gap. The “Bird’s Eye View” section describes MBCT as integrating mindfulness with CBT, but the paper does not establish this gap specifically for mindfulness embedded in individual CBT sessions. Page numbers are unavailable in our copy. (LLM, conf=0.82)
Experimental — accuracy not yet measuredMBIs aim to understand the root causes of human distress and alleviate it through mindfulness training.
“MBIs aim to understand the root causes of human distress and alleviate it through mindfulness training (Dimidjian & Segal, 2015).”
From Mapping mindfulness in psychotherapy: a scoping review on conceptualization, applications, and research directions (2026) · cites this paper as Dimidjian & Segal, 2015
The Clinical Application of Mindfulness section (page unavailable) describes mindfulness meditation as a core component of MBIs, taught to help prevent depression or reduce stress. Recommendation 1 describes research identifying a specific process involved in depressive relapse and a rationale for addressing it with meditation. The paper does not characterize MBIs as aiming to understand the root causes of human distress generally. (LLM, conf=0.85)
Experimental — accuracy not yet measured
The field has been limited by methodological gaps that restrict the reach and relevance of conclusions from the current literature.
“However, as noted by Dimidjian and Segal, 65 the field has been limited by a number of methodological gaps that restrict both the reach and relevance of the conclusions that can be drawn from the current literature.”
From Mindfulness-Based Interventions for Anxiety and Depression (2017) · cites this paper as [65]
The mapping of the MBP evidence base onto the NIH Stage Model by Dimidjian & Segal clarifies that the evidence is heavily saturated in Stage I, lightly represented in Stages 0 and II, and that to date there is minimal research in Stages III, IV and V.
“The mapping of the MBP evidence base onto this model by Dimidjian & Segal clari fi es that the evidence is heavily saturated in Stage I, lightly represented in Stages 0 and II, and that to date there is minimal research in Stages III, IV and V.”
From What defines mindfulness-based programs? The warp and the weft (2017) · cites this paper as Dimidjian & Segal (2015)
Dimidjian and Segal caution that the rapid proliferation of new potential contexts and populations risks neglecting the importance of foundational specification of clear intervention targets and mediating processes of change on which subsequent research can build.
“Dimidjian & Segal (2015) caution that the rapid proliferation of new potential contexts and populations risks neglecting the importance of foundational speci fi cation of clear intervention targets and mediating processes of change on which subsequent research can build.”
From What defines mindfulness-based programs? The warp and the weft (2017) · cites this paper as Dimidjian & Segal (2015)
There is a scarcity of studies investigating the implementation and dissemination of MBIs.
“there is a scarcity of studies investigating the implementation and dissemination of MBIs.”
From A mindfulness-based intervention for Substance Use Disorder in a Brazilian vulnerable population: a feasibility mixed method study (2024) · cites this paper as [15]
There is a lack of effectiveness studies of MBSR.
“Dimidjian and Segal have pointed out the lack of effectiveness studies of MBSR [18].”
The personal practice of mindfulness for the teacher is critical.
“The personal practice of mindfulness for the teacher is critical (Dimidjian & Segal, 2015).”
From What works in mindfulness interventions for medically unexplained symptoms? A systematic review (2020) · cites this paper as Dimidjian & Segal, 2015
Studies on MBIs have been predominantly conducted with WEIRD populations, which do not represent the majority of the global population.
“those that have been undertaken were predominantly conducted with WEIRD (western, educated, industrialized, rich, and democratic) populations, which do not represent the majority of the global population (14, 15).”
From A mindfulness-based intervention for Substance Use Disorder in a Brazilian vulnerable population: a feasibility mixed method study (2024) · cites this paper as [15]
The “Mapping the MBI Evidence Base” section categorizes studies by intervention and target population, but does not report whether their participants were predominantly WEIRD. Searches for WEIRD, Western or non-Western samples, and global representativeness found no passage addressing the claim. (LLM, conf=0.75)
Experimental — accuracy not yet measuredThe Mindfulness-Based Interventions: Teaching Assessment Criteria is a measure of mindfulness teaching skills that includes representation of common factors domains.
“The Mindfulness-Based Interventions: Teaching Assessment Criteria is a measure of mindfulness teaching skills that includes representation of common factors domains (for example, relational skills and holding the group learning environment such as setting clear ground rules and emphasizing the universality of themes which are discussed in the group156,157).”
From A common factors perspective on mindfulness-based interventions (2022) · cites this paper as [157]
Little is known about whether MBCT is delivered safely and effectively in real-world healthcare settings.
“However, little is known about whether MBCT is being delivered safely and effectively in real-world healthcare settings.”
From The Effectiveness of Mindfulness-Based Cognitive Therapy (MBCT) in Real-World Healthcare Services (2020) · cites this paper as Dimidjian and Segal 2015
Little is known about the outcomes of MBCT when delivered in real-world healthcare settings rather than research clinics.
“little is known about the outcomes of MBCT when delivered in real-world healthcare settings, rather than research clinics (Dimidjian & Segal., 2015).”
From The Effectiveness of Mindfulness-Based Cognitive Therapy (MBCT) in Real-World Healthcare Services (2020) · cites this paper as Dimidjian & Segal., 2015
MBIs with demonstrated efficacy in Stage II trials may fail to show effectiveness in Stage III and IV trials when delivered by community clinicians.
“This is indeed a challenge, as MBIs with demonstrated efficacy in Stage II trials may fail to show effectiveness in Stage III and IV trials when delivered by community clinicians.”
From Mindfulness-based treatment of addiction: current state of the field and envisioning the next wave of research (2018) · cites this paper as [86]
Mindfulness studies tend to over-represent positive results, while negative findings are either not published or obscured by post-hoc subgroup analyses or creative reinterpretations.
“Mindfulness studies tend to over-represent positive results, while negative findings are either not published or obscured by post-hoc subgroup analyses or creative reinterpretations [55–57].”
From Can mindfulness be too much of a good thing? The value of a middle way (2019) · cites this paper as [55]
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A qualitative analysis of mindfulness‐based cognitive therapy (MBCT) in Parkinson's disease
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Creswell, J. D. (2017) · Annual Review of Psychology · doi:10.1146/annurev-psych-042716-051139 · Cited by 1,702 · see citing works
Van Dam, N. T., van Vugt, M. K., Vago, D. R., Schmalzl, L., Saron, C. D., Olendzki, A., Meissner, T., Lazar, S. W., Kerr, C. E., Gorchov, J., et al. (2018) · Perspectives on Psychological Science · doi:10.1177/1745691617709589 · Cited by 1,506 · see citing works
What defines mindfulness-based programs? The warp and the weft
Crane, R. S., Brewer, J., Feldman, C., Kabat-Zinn, J., Santorelli, S., Williams, J. M. G., & Kuyken, W. (2017) · Psychological Medicine · doi:10.1017/s0033291716003317 · Cited by 868 · see citing works
Mindfulness-Based Interventions for Anxiety and Depression
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“However, as noted by Dimidjian and Segal, 65 the field has been limited by a number of methodological gaps that restrict both the reach and relevance of the conclusions that can be drawn from the current literature.”
Lutz, A., Jha, A. P., Dunne, J. D., & Saron, C. D. (2015) · American Psychologist · doi:10.1037/a0039585 · Cited by 697 · see citing works
Goldberg, S. B., Riordan, K. M., Sun, S., & Davidson, R. J. (2022) · Perspectives on Psychological Science · doi:10.1177/1745691620968771 · Cited by 520 · see citing works
“For MBIs with established efficacy (e.g., MBCT for prevention depression relapse), dissemination and implementation RCTs may be appropriate (Dimidjian & Segal, 2015).”
BackgroundMindfulness Meditation and Psychopathology
Wielgosz, J., Goldberg, S. B., Kral, T. R. A., Dunne, J. D., & Davidson, R. J. (2019) · Annual Review of Clinical Psychology · doi:10.1146/annurev-clinpsy-021815-093423 · Cited by 435 · see citing works
Mindfulness and Behavior Change
Schuman-Olivier, Z., Trombka, M., Lovas, D. A., Brewer, J. A., Vago, D. R., Gawande, R., Dunne, J. P., Lazar, S. W., Loucks, E. B., & Fulwiler, C. (2020) · Harvard Review of Psychiatry · doi:10.1097/hrp.0000000000000277 · Cited by 435 · see citing works
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Defining and Measuring Meditation-Related Adverse Effects in Mindfulness-Based Programs
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Can mindfulness be too much of a good thing? The value of a middle way
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Mindfulness-Based Interventions in Psychiatry
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“Additionally, limited studies have examined the effectiveness of MBIs in real-life settings (92) and how best to disseminate these efficacious interventions into the community.”
BackgroundFredrickson, B. L., Boulton, A. J., Firestine, A. M., Cappellen, P. V., Algoe, S. B., Brantley, M. M., Kim, S. L., Brantley, J. G., & Salzberg, S. (2017) · Mindfulness · doi:10.1007/s12671-017-0735-9 · Cited by 157 · see citing works
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Self-citationIs mindfulness research methodology improving over time? A systematic review
Goldberg, S. B., Tucker, R. P., Greene, P. A., Simpson, T. L., Kearney, D. J., & Davidson, R. J. (2017) · PLOS ONE · doi:10.1371/journal.pone.0187298 · Cited by 125 · see citing works
Mindfulness-Based Programs: Why, When, and How to Adapt?
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The Utility of Home-Practice in Mindfulness-Based Group Interventions: A Systematic Review
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The Effectiveness of Mindfulness-Based Cognitive Therapy (MBCT) in Real-World Healthcare Services
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When Fathers Begin to Falter: A Comprehensive Review on Paternal Perinatal Depression
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The epistemic and pragmatic value of non-action: a predictive coding perspective on meditation
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Mindfulness and physical disease: a concise review
Greeson, J. M., & Chin, G. R. (2019) · Current Opinion in Psychology · doi:10.1016/j.copsyc.2018.12.014 · Cited by 85 · see citing works
What do people mean when they talk about mindfulness?
Choi, E., Farb, N. A. S., Pogrebtsova, E., Gruman, J. A., & Grossmann, I. (2021) · Clinical Psychology Review · doi:10.1016/j.cpr.2021.102085 · Cited by 88 · see citing works
Mindfulness for Global Public Health: Critical Analysis and Agenda
Oman, D. (2025) · Mindfulness · doi:10.1007/s12671-023-02089-5 · Cited by 87 · see citing works
Mindfulness practice for protecting mental health during the COVID-19 pandemic
Zhu, J. L., Schülke, R., Vatansever, D., Xi, D., Yan, J., Zhao, H., Xie, X., Feng, J., Chen, M. Y., Sahakian, B. J., et al. (2021) · Translational Psychiatry · doi:10.1038/s41398-021-01459-8 · Cited by 83 · see citing works
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Implementing Mindfulness in the Mainstream: Making the Path by Walking It
Crane, R. S. (2017) · Mindfulness · doi:10.1007/s12671-016-0632-7 · Cited by 81 · see citing works
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Intervention Integrity in Mindfulness-Based Research
Crane, R. S., & Hecht, F. M. (2018) · Mindfulness · doi:10.1007/s12671-018-0886-3 · Cited by 75 · see citing works
A common factors perspective on mindfulness-based interventions
Goldberg, S. B. (2022) · Nature Reviews Psychology · doi:10.1038/s44159-022-00090-8 · Cited by 75 · see citing works
Designing a Resilience Program for Critical Care Nurses
Mealer, M. L., Hodapp, R. M., Conrad, D., Dimidjian, S., ROTHBAUM, B. O., & Moss, M. M. (2017) · AACN Advanced Critical Care · doi:10.4037/aacnacc2017252 · Cited by 74 · see citing works
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Roeser, R. W., Greenberg, M. T., Frazier, T., Galla, B. M., Semenov, A. D., & Warren, M. T. (2023) · Mindfulness · doi:10.1007/s12671-022-02017-z · Cited by 70 · see citing works
“…for experimental studies of programs in schools parallel suggestions made for the science of mindfulness in general (Davidson & Kaszniak, 2015; Dimidjian & Segal, 2015), and build upon work in the broader field of social and emotional learning (SEL) in schools around the study of program…”
Berghoff, C. R., Wheeless, L. E., Ritzert, T. R., Wooley, C. M., & Forsyth, J. P. (2017) · Mindfulness · doi:10.1007/s12671-017-0717-y · Cited by 64 · see citing works
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“…from the perspective of the National Institutes of Health Stage Model, Dimidjian and Segal (2015) reported the preponderance of evidence thus far has been focused on stage I research, intervention development, and, to a lesser extent, on basic science and efficacy trials (Dimidjian and Segal 2015).”
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Ruijgrok-Lupton, P. E., Crane, R. S., & Dorjee, D. (2018) · Mindfulness · doi:10.1007/s12671-017-0750-x · Cited by 64 · see citing works
Mindfulness-based cognitive therapy for residual depressive symptoms and relapse prophylaxis
Segal, Z. V., & Walsh, K. (2015) · Current Opinion in Psychiatry · doi:10.1097/yco.0000000000000216 · Cited by 62 · see citing works
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“Many clinicians in routine care apply mindfulness exercises in individual therapy (Cigolla & Brown, 2011; Demarzo et al., 2015; Dimidjian & Segal, 2015) and already do so during their training (Ivanovic, Swift, Callahan, & Dunn, 2015; Mander et al., 2017a).”
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Mindfulness and Decision‐Making Style: Predicting Career Thoughts and Vocational Identity
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“However, it remains to be tested whether practice-specific skills acquired during the course of the intervention differentially mediated outcomes for these two treatments or if improvements were instead related to non-specific factors [20].”
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Mindfulness-Based Interventions and the Hypothalamic–Pituitary–Adrenal Axis: A Systematic Review
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Mindfulness-based interventions for addictive behaviors: implementation issues on the road ahead
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First, do no harm: An intensive experience sampling study of adverse effects to mindfulness training
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Principles for a Responsible Integration of Mindfulness in Individual Therapy
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Self-citationBuilding a More Diverse and Inclusive Science: Mindfulness-Based Approaches for Latinx Individuals
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A Pilot Randomized Controlled Trial of a Mindfulness Program for Filipino Children
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The Inside Out Group Model: Teaching Groups in Mindfulness-Based Programs
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The effect of ten versus twenty minutes of mindfulness meditation on state mindfulness and affect
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Mindfulness-Based Intervention Development for Children and Adolescents
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- Authors
- Dimidjian, S., & Segal, Z. V.
- Affiliations
- University of Colorado Boulder (US)
- University of Toronto (CA)
- Venue
- American Psychologist
- Published
- 2015-10
- Volume
- 70
- Issue
- 7
- Pages
- 593-620
- ISSN
- 0003-066X (ISSN-L)
- 1935-990X
- PMC
- PMC5853107
- OpenAlex
- W2398456569
- Cited by
- 291
- References
- 342
- Citations by year
- 2026: 12 · 2025: 16 · 2024: 29 · 2023: 29 · 2022: 25 · 2021: 34 · 2020: 36 · 2019: 34 · 2018: 35 · 2017: 27 · 2016: 12 · 2015: 2
- FWCI
- 31.41
- Type
- journal article
- Language
- en
- Open access
- green
- www.ncbi.nlm.nih.gov
- Locations
- American Psychologist (publishedVersion)
- PubMed (publishedVersion)
- Europe PMC (PubMed Central) (acceptedVersion)
- PubMed Central (acceptedVersion)
- Funders
- National Institute of Mental Health (R34MH083866, K23MH077287, R34MH087723)
- Topics
- Social Sciences › Psychology › Clinical Psychology › Mindfulness and Compassion Interventions
- Social Sciences › Psychology › Clinical Psychology › Psychotherapy Techniques and Applications
- Social Sciences › Psychology › Applied Psychology › Digital Mental Health Interventions
- Keywords
- mindfulness-based interventions, mindfulness-based cognitive therapy, mindfulness-based stress reduction, clinical translation, evidence base, research gaps, methodological quality, public health impact, mental health
- MeSH terms
- Humans, Mental Health, Stress, Psychological, Cognitive Behavioral Therapy, Mindfulness
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