Recommendations for Probiotic Use—2015 Update: Proceedings and Consensus Opinion
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This paper describes the consensus opinion of the participants in the 4th Triennial Yale/Harvard Workshop on Probiotic Recommendations. The recommendations update those of the first 3 meetings that were published in 2006, 2008, and 2011. Recommendations for the use of probiotics in necrotizing enterocolitis, childhood diarrhea, inflammatory bowel disease, irritable bowel syndrome and Clostridium difficile diarrhea are reviewed. In addition, we have added recommendations for liver disease for the first time. As in previous publications, the recommendations are given as A, B, or C ratings.
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Our findings do not support recommendations for the use of specific probiotics for acute infectious diarrhoea in children.
“Our findings do not support recommendations for the use of specific probiotics for acute infectious diarrhoea in children (Floch 2015; Guarino 2018; Sniffen 2018).”
From Probiotics for treating acute infectious diarrhoea (2020) · cites this paper as Floch 2015
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- Authors
- Floch, M. H., Walker, W. A., Sanders, M. E., Nieuwdorp, M., Kim, A. S., Brenner, D. A., Qamar, A. A., Miloh, T. A., Guarino, A., Guslandi, M., Dieleman, L. A., Ringel, Y., Quigley, E. M. M., & Brandt, L. J.
- Affiliations
- Lahey Hospital and Medical Center (US)
- Harvard University (US)
- Amsterdam UMC Location University of Amsterdam (NL)
- MNGI Digestive Health (US)
- Yale University (US)
- University of Gothenburg (SE)
- Massachusetts General Hospital (US)
- Corresponding author
- Floch, Martin H.
- Brenner, David A.
- Dieleman, Levinus A.
- ORCID
- Venue
- Journal of Clinical Gastroenterology
- Published
- 2015-11
- Volume
- 49
- Issue
- Supplement 1
- Pages
- S69-S73
- ISSN
- 0192-0790 (ISSN-L)
- OpenAlex
- W2199248144
- Semantic Scholar
- fbce8a5e5d792c961602f656b449e7da6574b22c
- Cited by
- 119
- References
- 64
- Citations by year
- 2026: 2 · 2025: 1 · 2024: 5 · 2023: 6 · 2022: 9 · 2021: 8 · 2020: 16 · 2019: 15 · 2018: 13 · 2017: 24 · 2016: 18 · 2015: 1
- FWCI
- 24.97
- Type
- journal article
- Language
- en
- Open access
- green
- pure.amsterdamumc.nl
- Licence
- other-oa
- Locations
- Journal of Clinical Gastroenterology (publishedVersion)
- PubMed (publishedVersion)
- Amsterdam UMC (VU Amsterdam) - Institutional Repository (publishedVersion)
- Pure Amsterdam UMC (submittedVersion, other-oa)
- Data Archiving and Networked Services (DANS) (submittedVersion)
- Funders
- National Institutes of Health (DK040561)
- National Institute of Diabetes and Digestive and Kidney Diseases (P01DK033506, P30DK040561, T32DK007191)
- Eunice Kennedy Shriver National Institute of Child Health and Human Development (R01HD059126, R01HD012437)
- Topics
- Life Sciences › Agricultural and Biological Sciences › Food Science › Probiotics and Fermented Foods
- Health Sciences › Medicine › Gastroenterology › Gastrointestinal motility and disorders
- Life Sciences › Biochemistry, Genetics and Molecular Biology › Molecular Biology › Gut microbiota and health
- Keywords
- probiotics, clinical guidelines, necrotizing enterocolitis, childhood diarrhea, inflammatory bowel disease, irritable bowel syndrome, Clostridium difficile-associated diarrhea, liver disease, probiotic therapy
- MeSH terms
- Adult, Child, Diarrhea, Enterocolitis, Pseudomembranous, Humans, Liver Diseases, Clostridioides difficile, Probiotics, Enterocolitis, Necrotizing, Irritable Bowel Syndrome
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