Does computerized cognitive behavioral therapy help people with inflammatory bowel disease? A randomized controlled trial
Open accessAbstract
BACKGROUND: Cognitive behavioral therapy may be useful for improving health-related quality of life (HRQOL) of at least some patients with inflammatory bowel disease (IBD), especially those with psychiatric comorbidities. However, cognitive behavioral therapy can be difficult to access. These difficulties can be overcome by computerized cognitive behavioral therapy (CCBT). This is a randomized controlled trial of a self-administered CCBT intervention for patients with IBD focused on improving HRQOL. It is hypothesized that CCBT completers will have an improved HRQOL relative to people not allocated to CCBT. METHODS: Patients with IBD were randomly allocated to CCBT (n = 113) versus treatment as usual (n = 86). The IBD Questionnaire at 12 weeks after baseline was the primary outcome, while generic HRQOL, anxiety, depression, coping strategies, perceived stress, and IBD symptoms were secondary outcomes. Outcomes were also measured at 6 months after baseline. Predictors of dropout were also determined. RESULTS: Twenty-nine CCBT participants (25.7%) completed the CCBT. The IBD Questionnaire was significantly increased at 12 weeks in CCBT completers compared with treatment-as-usual patients (F = 6.38, P = 0.01). Short Form-12 mental score (F = 5.00, P = 0.03) was also significantly better in CCBT compared with treatment-as-usual patients at 12 weeks. These outcomes were not maintained at 6 months. The predictors of dropout were baseline depression, biological use, lower IBD Questionnaire scores, and not having steroids. CONCLUSIONS: Improvements at 12 weeks after baseline were not maintained at 6 months. Future research should aim to improve adherence rates. Moreover, CCBT may not work for patients with IBD with comorbid depression.
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Integrity signals
Registry
Cites
Statistics
Claims the paper makes
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Claims other papers make about this one
Each is checked against this paper’s own text: does it say what the citing paper says it does?
IBD behavioral trials usually do not report race and ethnicity, and when they do, most participants are White.
“While race and ethnicity are generally not presented in IBD behavioral trials, when race is included in studies, most participants are White.34”
From Culturally Informed Digital Behavioral Intervention Development for Inflammatory Bowel Disease: A Qualitative Study (2025) · cites this paper as [34]
Table 1 (in the Conclusions section; page unavailable) reports ethnicity for this IBD behavioral trial: 87.2% of controls and 88.5% of intervention participants were classified as solely NZ European. This supports a predominantly European sample in this trial, but the paper does not establish that IBD behavioral trials generally omit race and ethnicity or that most participants across trials are White. (LLM, conf=0.85)
Experimental — accuracy not yet measuredThe intervention sessions occur weekly for 8 weeks and take 1 hour, a duration established as effective.
“The sessions occur weekly for 8 weeks and take 1 hour (duration established as effective.30”
From Acceptance commitment therapy (ACT) for psychological distress associated with inflammatory bowel disease (IBD): protocol for a feasibility trial of the ACTforIBD programme (2022) · cites this paper as [30]
The Interventions section describes an eight-session program shortened to eight weeks, and the Participant contact section says a new topic was released each week. Our copy does not establish that sessions took one hour or that a one-hour duration was effective. (LLM, conf=0.87)
Experimental — accuracy not yet measuredThe present trial showed high retention, comparable to or better than other trials testing psychotherapy, specifically CBT, in an online only setting for IBD.
“The present trial showed high retention, which is comparable to or better than other trials testing psychotherapy, specifically CBT, in an online only setting for IBD.37,40”
From Feasibility, Acceptability, and Preliminary Efficacy of Acceptance Commitment Therapy for Adults Living With Inflammatory Bowel Disease and Distress. (2024) · cites this paper as [40]
Self-check
Percentages, sums and reported differences re-computed from the paper’s own numbers.
The self-check needs the paper’s full text.
Cites
The Hospital Anxiety and Depression Scale
Zigmond, A. S., & Snaith, R. P. (1983) · Acta Psychiatrica Scandinavica · doi:10.1111/j.1600-0447.1983.tb09716.x · Cited by 47,139 · see citing works
A Global Measure of Perceived Stress
Cohen, S., Kamarck, T., & Mermelstein, R. (1983) · Journal of Health and Social Behavior · doi:10.2307/2136404 · Cited by 32,807 · see citing works
WARE, J. E., KOSINSKI, M., & KELLER, S. D. (1996) · Medical Care · doi:10.1097/00005650-199603000-00003 · Cited by 17,392 · see citing works
The validity of the Hospital Anxiety and Depression Scale
Bjelland, I., Dahl, A. A., Haug, T. T., & Neckelmann, D. (2002) · Journal of Psychosomatic Research · doi:10.1016/s0022-3999(01)00296-3 · Cited by 9,779 · cited 1× · see citing works
“Sensitivity and specificity are optimum when caseness is defined at 8 or above for the anxiety and depression subscales.(39) The Hospital Anxiety and Depression Scale has been used extensively in IBD studies.”
MethodYou want to measure coping but your protocol’ too long: Consider the brief cope
Carver, C. S. (1997) · International Journal of Behavioral Medicine · doi:10.1207/s15327558ijbm0401_6 · Cited by 7,361 · see citing works
(1975) · Medical Entomology and Zoology · Cited by 7,245 · see citing works
A SIMPLE INDEX OF CROHN'S-DISEASE ACTIVITY
Harvey, R. F., & Bradshaw, J. M. (1980) · The Lancet · doi:10.1016/s0140-6736(80)92767-1 · Cited by 2,974 · see citing works
The immunological and genetic basis of inflammatory bowel disease
Bouma, G., & Strober, W. (2003) · Nature reviews. Immunology · doi:10.1038/nri1132 · Cited by 1,882 · see citing works
Computer-based psychological treatments for depression: A systematic review and meta-analysis
Richards, D., & Richardson, T. (2012) · Clinical Psychology Review · doi:10.1016/j.cpr.2012.02.004 · Cited by 1,442 · see citing works
A simple clinical colitis activity index
Walmsley, R. S., Ayres, R., Pounder, R. E., & Allan, R. N. (1998) · Gut · doi:10.1136/gut.43.1.29 · Cited by 1,320 · see citing works
Thinking and Depression: I. Idiosyncratic Content and Cognitive Distortions
BECK, A. T. (1963) · Archives of General Psychiatry · doi:10.1001/archpsyc.1963.01720160014002 · Cited by 1,308 · see citing works
Adherence in Internet Interventions for Anxiety and Depression
Christensen, H., Griffiths, K. M., & Farrer, L. (2009) · Journal of Medical Internet Research · doi:10.2196/jmir.1194 · Cited by 1,133 · see citing works
Thinking and Depression: II. Theory and Therapy
BECK, A. T. (1964) · Archives of General Psychiatry · doi:10.1001/archpsyc.1964.01720240015003 · Cited by 820 · see citing works
Irvine, E. J., Feagan, B. G., Rochon, J., Archambault, A., Fedorak, R. N., Groll, A., Kinnear, D. G., Saibil, F. G., & McDonald, J. W. (1994) · Gastroenterology · doi:10.1016/0016-5085(94)90585-1 · Cited by 709 · see citing works
Depression and anxiety in inflammatory bowel disease: A review of comorbidity and management
Graff, L. A., Walker, J. R., & Bernstein, C. N. (2009) · Inflammatory Bowel Diseases · doi:10.1002/ibd.20873 · Cited by 586 · see citing works
Bernstein, C. N., Fried, M., Krabshuis, J., Cohen, H., Eliakim, R., Fedail, S. S., Gearry, R. B., Goh, K., Hamid, S., Khan, A. G., et al. (2009) · Inflammatory Bowel Diseases · doi:10.1002/ibd.21048 · Cited by 522 · see citing works
Self-citationClinical Outcome After Short-term Psychotherapy for Adolescents With Major Depressive Disorder
Birmaher, B. B., Brent, D. A., Kolko, D. J., BAUGHER, M., Bridge, J. A., Holder, D., Iyengar, S., & Ulloa, R. E. (2000) · Archives of General Psychiatry · doi:10.1001/archpsyc.57.1.29 · Cited by 374 · see citing works
Kaltenthaler, E., Brazier, J., De Nigris, E., Tumur, I., Ferriter, M., Beverley, C., Parry, G., Rooney, G., & Sutcliffe, P. (2006) · Health Technology Assessment · doi:10.3310/hta10330 · Cited by 357 · see citing works
The Social Functioning Questionnaire: A Rapid and Robust Measure of Perceived Functioning
Tyrer, P. J., Nur, U., Crawford, M., Karlsen, S., Maclean, C., Rao, B., & Johnson, T. L. (2005) · International Journal of Social Psychiatry · doi:10.1177/0020764005057391 · Cited by 348 · see citing works
Validity and Reliability of the Brief COPE in Carers of People With Dementia
Cooper, C., Katona, C., & Livingston, G. (2008) · The Journal of Nervous and Mental Disease · doi:10.1097/nmd.0b013e31818b504c · Cited by 306 · see citing works
Jackson, C., Clatworthy, J., Robinson, A., & Horne, R. (2009) · The American Journal of Gastroenterology · doi:10.1038/ajg.2009.685 · Cited by 287 · see citing works
Patient defined dichotomous end points for remission and clinical improvement in ulcerative colitis
Higgins, P. D. R., Schwartz, M., Mapili, J., Krokos, I., Leung, J., & Zimmermann, E. M. (2005) · Gut · doi:10.1136/gut.2004.056358 · Cited by 244 · see citing works
Population‐based cases control study of inflammatory bowel disease risk factors
Gearry, R. B., Richardson, A. K., FRAMPTON, C. M. A., Dodgshun, A. J., & Barclay, M. L. (2010) · Journal of Gastroenterology and Hepatology · doi:10.1111/j.1440-1746.2009.06140.x · Cited by 237 · see citing works
Self-citationMichaels, J. A., Campbell, W. B., Brazier, J. E., MacIntyre, J., Palfreyman, S. J., Ratcliffe, J., & Rigby, K. A. (2006) · Health Technology Assessment · doi:10.3310/hta10130 · Cited by 224 · see citing works
Journal of health & social behavior
Jstor (1967) · Cited by 214 · see citing works
Web-Based Depression Treatment for Type 1 and Type 2 Diabetic Patients
van Bastelaar, K. M. P., Pouwer, F., Cuijpers, P., Riper, H., & Snoek, F. J. (2011) · Diabetes Care · doi:10.2337/dc10-1248 · Cited by 209 · see citing works
The Eysenck Personality Questionnaire Brief Version: Factor Structure and Reliability
Sato, T. (2005) · The Journal of psychology · doi:10.3200/jrlp.139.6.545-552 · Cited by 178 · see citing works
The UK IBDQ—A British version of the inflammatory bowel disease questionnaire
Cheung, W., Garratt, A., Russell, I. T., & Williams, J. G. (2000) · Journal of Clinical Epidemiology · doi:10.1016/s0895-4356(99)00152-3 · Cited by 149 · see citing works
Porcell, P., Leoci, C., & Guerra, V. (1996) · Scandinavian Journal of Gastroenterology · doi:10.3109/00365529609010354 · Cited by 139 · see citing works
Brief cognitive-behavioral internet therapy for irritable bowel syndrome
Hunt, M. G., Moshier, S., & Milonova, M. (2009) · Behaviour Research and Therapy · doi:10.1016/j.brat.2009.05.002 · Cited by 139 · see citing works
Psychiatric Predictors of Noncompliance in Inflammatory Bowel Disease
Nigro, G., Angelini, G., Grosso, S. B., Caula, G., & Sategna-Guidetti, C. (2001) · Journal of Clinical Gastroenterology · doi:10.1097/00004836-200101000-00015 · Cited by 114 · see citing works
Computer-aided treatments of mental health problems.
Marks, I. M., Shaw, S. M., & Parkin, R. (1998) · Clinical Psychology Science and Practice · doi:10.1111/j.1468-2850.1998.tb00141.x · Cited by 113 · see citing works
KROLL, L., HARRINGTON, R., JAYSON, D., FRASER, J., & GOWERS, S. (1996) · Journal of the American Academy of Child & Adolescent Psychiatry · doi:10.1097/00004583-199609000-00013 · Cited by 106 · see citing works
Jarrett, R. B., Eaves, G., Grannemann, B. D., & Rush, A. J. (1991) · Psychiatry Research · doi:10.1016/0165-1781(91)90061-s · Cited by 105 · see citing works
Psychotherapy for inflammatory bowel disease: a review and update
McCombie, A. M., Mulder, R. T., & Gearry, R. B. (2013) · Journal of Crohn s and Colitis · doi:10.1016/j.crohns.2013.02.004 · Cited by 105 · see citing works
Psychotherapy with chronic inflammatory bowel disease patients: A Review
von Wietersheim, J., & Kessler, H. (2006) · Inflammatory Bowel Diseases · doi:10.1097/01.mib.0000236925.87502.e0 · Cited by 103 · see citing works
Nahon, S., Lahmek, P., Saas, C., Durance, C., Olympie, A., Lesgourgues, B., & Gendre, J.-P. (2011) · Inflammatory Bowel Diseases · doi:10.1002/ibd.21482 · Cited by 102 · see citing works
Pros and cons of online cognitive–behavioural therapy
Andersson, G., & Cuijpers, P. (2008) · British Journal of Psychiatry · doi:10.1192/bjp.bp.108.054080 · Cited by 101 · see citing works
Pallis, A. G., Vlachonikolis, I. G., & Mouzas, I. (2002) · BMC Gastroenterology · doi:10.1186/1471-230x-2-1 · Cited by 96 · see citing works
Jantschek, G. (1998) · Scandinavian Journal of Gastroenterology · doi:10.1080/00365529850172386 · Cited by 92 · see citing works
How IBD patients cope with IBD: A systematic review
McCombie, A., Mulder, R., & Gearry, R. B. (2012) · Journal of Crohn s and Colitis · doi:10.1016/j.crohns.2012.05.021 · Cited by 89 · see citing works
Self-citationSmith, G. D., Watson, R. A., Roger, D., McRorie, E., Hurst, N. P., Luman, W., & Palmer, K. R. (2002) · Journal of Advanced Nursing · doi:10.1046/j.1365-2648.2002.02159.x · Cited by 89 · see citing works
A Roadmap to Computer-Based Psychotherapy in the United States
Cartreine, J. A., Ahern, D. K., & Locke, S. E. (2010) · Harvard Review of Psychiatry · doi:10.3109/10673221003707702 · Cited by 88 · see citing works
Irvine, E. J., Feagan, B. G., & Wong, C. J. (1996) · Journal of Clinical Epidemiology · doi:10.1016/0895-4356(96)00136-9 · Cited by 83 · see citing works
Carter, J. D., Luty, S. E., McKenzie, J. M., Mulder, R., FRAMPTON, C. M. A., & Joyce, P. R. (2010) · Journal of Affective Disorders · doi:10.1016/j.jad.2010.07.002 · Cited by 82 · see citing works
Self-citationVAN DEN BERG, S., SHAPIRO, D. A., BICKERSTAFFE, D., & CAVANAGH, K. (2004) · Journal of Psychiatric and Mental Health Nursing · doi:10.1111/j.1365-2850.2004.00745.x · Cited by 64 · see citing works
Keefer, L., Doerfler, B., & Artz, C. (2011) · Inflammatory Bowel Diseases · doi:10.1002/ibd.21679 · Cited by 56 · see citing works
Evaluation of a psychoeducational intervention for adolescents with inflammatory bowel disease
Grootenhuis, M. A., Maurice-Stam, H., Derkx, B. H., & Last, B. F. (2009) · European Journal of Gastroenterology & Hepatology · doi:10.1097/meg.0b013e328315a215 · Cited by 48 · see citing works
Bennett-Levy, J., & Perry, H. (2009) · Australasian Psychiatry · doi:10.1080/10398560902948126 · Cited by 43 · see citing works
The Potential Role of a Self-Management Intervention for Ulcerative Colitis
Keefer, L., Kiebles, J. L., Kwiatek, M. A., Palsson, O. S., Taft, T., Martinovich, Z., & Barrett, T. A. (2011) · Biological Research For Nursing · doi:10.1177/1099800410397629 · Cited by 43 · see citing works
Knowles, S. R., & Mikocka‐Walus, A. A. (2014) · Scandinavian Journal of Gastroenterology · doi:10.3109/00365521.2013.865259 · Cited by 43 · see citing works
Self-citationMcCombie, A., Gearry, R., Andrews, J., Mikocka-Walus, A., & Mulder, R. (2015) · Journal of Clinical Psychology in Medical Settings · doi:10.1007/s10880-015-9420-0 · Cited by 42 · see citing works
Self-citationPraško, J. P., Jelenova, D., & Mihál, V. (2010) · Biomedical Papers · doi:10.5507/bp.2010.046 · Cited by 34 · see citing works
McCombie, A., Gearry, R. B., & Mulder, R. (2013) · Journal of Crohn s and Colitis · doi:10.1016/j.crohns.2013.11.011 · Cited by 15 · see citing works
Self-citationVisser, M., Geelen, A., Pot, G. K., van Bergeijk, J., Brehler, H. D., Kampman, E., & Witteman, B. J. M. (2008) · Journal of Crohn s and Colitis Supplements · doi:10.1016/s1873-9954(08)70046-6 · Cited by 4 · see citing works
Visser, M., Geelen, A., Pot, G. K., van Bergeijk, J. D., Brehler, H. D., Kampman, E., & Witteman, B. J. M. (2008) · Psychologie & gezondheid · doi:10.1007/bf03077472 · Cited by 3 · see citing works
Krankheitsbelastung bei chronisch entzündlichen Darmerkrankungen
Krille, S., Schöne, C., & Martin, A. (2010) · Psychotherapeut · doi:10.1007/s00278-010-0743-x · Cited by 2 · see citing works
Flagged first, then by citations
Research works printed but not linked: 2
- Beck, A. T. Thinking and depression. Arch Gen Psychiatry. 1963; 9:324-33.
- Krille, S., Schone, C. and Martin, A. Disease distress in inflammatory bowel disease. Relevance of subjective illness perceptions. Psychotherapeut. 2010 May; 55(3):209-216.
Cited by
Sorted by citations
Gracie, D. J., Irvine, A. J., Sood, R., Mikocka-Walus, A., Hamlin, P. J., & Ford, A. C. (2017) · The Lancet Gastroenterology & Hepatology · doi:10.1016/s2468-1253(16)30206-0 · Cited by 271 · see citing works
Self-citationGracie, D. J., Williams, C. J. M., Sood, R., Mumtaz, S., Bholah, H. M., Hamlin, J. P., & Ford, A. C. (2016) · American Journal of Gastroenterology · doi:10.1038/ajg.2016.59 · Cited by 173 · see citing works
EHealth Technologies in Inflammatory Bowel Disease: A Systematic Review.
Jackson, B. D., Gray, K., Knowles, S. R., & De Cruz, P. (2016) · Journal of Crohn's and Colitis · doi:10.1093/ecco-jcc/jjw059 · Cited by 126 · see citing works
Siaw, M. Y. L., Ko, Y., Malone, D. C., Tsou, K. Y. K., Lew, Y., Foo, D. C. G., Tan, E. J. H., Chan, S. C., Chia, A., Sinaram, S. S., et al. (2017) · Journal of Clinical Pharmacy and Therapeutics · doi:10.1111/jcpt.12536 · Cited by 103 · see citing works
White, V., Linardon, J., Stone, J. E., Holmes-Truscott, E., Olive, L., Mikocka-Walus, A., Hendrieckx, C., Evans, S., & Speight, J. (2022) · Psychological Medicine · doi:10.1017/s0033291720002251 · Cited by 90 · see citing works
Self-citationRiggott, C., Mikocka-Walus, A., Gracie, D. J., & Ford, A. C. (2023) · The Lancet Gastroenterology & Hepatology · doi:10.1016/s2468-1253(23)00186-3 · Cited by 83 · see citing works
Self-citationBeyond intent to treat (ITT): A complier average causal effect (CACE) estimation primer
Peugh, J., Strotman, D., McGrady, M. E., Rausch, J. R., & Kashikar‐Zuck, S. (2016) · Journal of School Psychology · doi:10.1016/j.jsp.2015.12.006 · Cited by 85 · see citing works
Mikocka-Walus, A., Bampton, P., Hetzel, D., Hughes, P., Esterman, A., & Andrews, J. M. (2017) · International Journal of Behavioral Medicine · doi:10.1007/s12529-016-9580-9 · Cited by 78 · see citing works
Self-citationZhang, M., Hong, L., Zhang, T., Lin, Y., Zheng, S., Zhou, X., Fan, R., Wang, Z., Zhang, C.-L., & Zhong, J. (2016) · Patient Preference and Adherence · doi:10.2147/ppa.s118413 · Cited by 76 · see citing works
Helsel, B. C., Williams, J. E., Lawson, K. N., Liang, J., & Markowitz, J. E. (2018) · Digestive Diseases and Sciences · doi:10.1007/s10620-018-5054-z · Cited by 72 · see citing works
Lores, T. J., Goess, C., Mikocka‐Walus, A. A., Collins, K., Burke, A. L. J., Chur‐Hansen, A., Delfabbro, P., & Andrews, J. M. (2019) · Journal of Crohn s and Colitis · doi:10.1093/ecco-jcc/jjz026 · Cited by 70 · see citing works
Self-citationBehavioural medicine and gastrointestinal disorders: the promise of positive psychology
Keefer, L. (2018) · Nature Reviews Gastroenterology & Hepatology · doi:10.1038/s41575-018-0001-1 · Cited by 69 · see citing works
Hirten, R. P., Danieletto, M., Scheel, R., Shervey, M., Ji, J., Hu, L., Sauk, J., Chang, L., Arnrich, B., Bӧttinger, E., et al. (2021) · Inflammatory Bowel Diseases · doi:10.1093/ibd/izaa323 · Cited by 60 · see citing works
Pang, L., Liu, H., Liu, Z., Tan, J., Zhou, L., Qiu, Y., Lin, X., He, J., Li, X., Lin, S., et al. (2021) · Journal of Medical Internet Research · doi:10.2196/28978 · Cited by 68 · see citing works
DUFF, W. R. D., Haskey, N., Potter, G., Alcorn, J., Hunter, P. V., & Fowler, S. A. (2018) · World Journal of Gastroenterology · doi:10.3748/wjg.v24.i28.3055 · Cited by 60 · see citing works
Tarricone, I., Regazzi, M. G., Bonucci, G., Rizzello, F., Carini, G., Muratori, R., Poggioli, G., & Campieri, M. (2017) · Journal of Psychosomatic Research · doi:10.1016/j.jpsychores.2017.07.001 · Cited by 53 · see citing works
Hanlon, I., Hewitt, C. E., Bell, K. J., Phillips, A., & Mikocka‐Walus, A. A. (2018) · Alimentary Pharmacology & Therapeutics · doi:10.1111/apt.14840 · Cited by 50 · see citing works
Self-citationHunt, M. G., Loftus, P., Accardo, M., Keenan, M., Cohen, L., & Osterman, M. T. (2019) · Journal of Clinical Psychology in Medical Settings · doi:10.1007/s10880-019-09621-7 · Cited by 50 · see citing works
Psychological factors associated with inflammatory bowel disease
Eugenicos, M. P., & Ferreira, N. B. (2021) · British Medical Bulletin · doi:10.1093/bmb/ldab010 · Cited by 50 · see citing works
The effect of psychotherapy on quality of life in IBD Patients: A systematic review
Paulides, E., Boukema, I., van der Woude, C. J., & de Boer, N. K. H. (2021) · Inflammatory Bowel Diseases · doi:10.1093/ibd/izaa144 · Cited by 47 · see citing works
Adjuvant therapy with antidepressants for the management of inflammatory bowel disease
Mikocka‐Walus, A. A., Fielder, A. L., Prady, S. L., Esterman, A., Knowles, S. R., & Andrews, J. M. (2017) · Cochrane Database of Systematic Reviews · doi:10.1002/14651858.cd012680 · Cited by 43 · see citing works
Self-citationNorton, C. S., Syred, J., Kerry, S., Artom, M., Sweeney, L., Hart, A. L., Czuber‐Dochan, W., Taylor, S. J., Mihaylova, B., Roukas, C., et al. (2021) · Trials · doi:10.1186/s13063-021-05466-4 · Cited by 41 · see citing works
(2020) · Deakin Research Online (Deakin University) · Cited by 41 · see citing works
Self-citationeHealth for inflammatory bowel disease self-management – the patient perspective
Con, D., Jackson, B., Gray, K., & De Cruz, P. (2017) · Scandinavian Journal of Gastroenterology · doi:10.1080/00365521.2017.1333625 · Cited by 38 · see citing works
Modifiable Environmental Factors in Inflammatory Bowel Disease
Burke, K. E., Boumitri, C., & Ananthakrishnan, A. N. (2017) · Current Gastroenterology Reports · doi:10.1007/s11894-017-0562-0 · Cited by 36 · see citing works
Peerani, F., Watt, M., Ismond, K. P., Whitlock, R., Ambrosio, L., Hotte, N., Mitchell, N., Bailey, R. J., Kroeker, K., Dieleman, L. A., et al. (2022) · Therapeutic Advances in Gastroenterology · doi:10.1177/17562848221127238 · Cited by 35 · see citing works
Davis, S. P., Bolin, L. P., Crane, P. B., & Crandell, J. (2020) · Frontiers in Psychology · doi:10.3389/fpsyg.2020.538741 · Cited by 32 · see citing works
E-health in inflammatory bowel diseases: More challenges than opportunities?
Bossuyt, P. J., Pouillon, L., Bonnaud, G., Danese, S., & Peyrin‐Biroulet, L. (2017) · Digestive and Liver Disease · doi:10.1016/j.dld.2017.08.026 · Cited by 29 · see citing works
Mind–Body Interventions for Pediatric Inflammatory Bowel Disease
Yeh, A. M., Wren, A. A., & Golianu, B. J. (2017) · Children · doi:10.3390/children4040022 · Cited by 30 · see citing works
Li, C., Hou, Z., Liu, Y., Ji, Y.-N., & Xie, L. (2018) · International Journal of Nursing Practice · doi:10.1111/ijn.12699 · Cited by 31 · see citing works
Mikocka‐Walus, A. A., Druitt, M. L., O’Shea, M., Skvarc, D., Watts, J. J., Esterman, A., Tsaltas, J., Knowles, S. R., Harris, J., Dowding, C., et al. (2021) · BMJ Open · doi:10.1136/bmjopen-2020-046603 · Cited by 30 · see citing works
Self-citationChen, Y., Chen, X., Lin, S., Huang, S., Li, L., Hong, M., Li, ., Ma, L., & Ma, J. (2025) · Chinese Medical Journal · doi:10.1097/cm9.0000000000003389 · Cited by 29 · see citing works
del Hoyo, J., Millán, M., Garrido‐Marín, A., & Aguas, M. (2023) · World Journal of Gastroenterology · doi:10.3748/wjg.v29.i7.1139 · Cited by 26 · see citing works
Johnson, E., Corrick, S., Isley, S., Vandermeer, B., Dolgoy, N., Bates, J., Godfrey, E., Soltys, C., Muir, C., Vohra, S., et al. (2024) · PLOS Digital Health · doi:10.1371/journal.pdig.0000435 · Cited by 24 · see citing works
Berens, S., Stroe‐Kunold, E., Kraus, F., Tesarz, J., Gauss, A., Niesler, B., Herzog, W., & Schaefert, R. (2017) · Journal of Psychosomatic Research · doi:10.1016/j.jpsychores.2017.12.002 · Cited by 23 · see citing works
van den Brink, G., Stapersma, L., Bom, A. S., Rizopolous, D., van der Woude, C. J., Stuyt, R. J. L., Hendriks, D. M., van der Burg, J. A. T., Beukers, R., Korpershoek, T. A., et al. (2019) · Inflammatory Bowel Diseases · doi:10.1093/ibd/izz073 · Cited by 23 · see citing works
Schliep, M. K., Chudy‐Onwugaje, K., Abutaleb, A., LANGENBERG, P. W., Regueiro, M. D., Schwartz, D. A., Tracy, J. K., Ghazi, L. J., Patil, S. A., Quezada, S. M., et al. (2020) · Crohn s & Colitis 360 · doi:10.1093/crocol/otaa002 · Cited by 23 · see citing works
Sweeney, L., Moss-Morris, R. E., Czuber‐Dochan, W., & Norton, C. S. (2021) · Pilot and Feasibility Studies · doi:10.1186/s40814-021-00829-9 · Cited by 23 · see citing works
Chen, J., Chen, X., Sun, Y., Xie, Y., Wang, X., Li, R., & Hesketh, T. M. (2021) · BMC Gastroenterology · doi:10.1186/s12876-021-02003-0 · Cited by 23 · see citing works
A Systematic Review of Self-Management Interventions for Patients with Inflammatory Bowel Disease
Iizawa, M., Hirose, L., Nunotani, M., Nakashoji, M., Tairaka, A., & Fernandez, J. L. (2023) · Inflammatory Intestinal Diseases · doi:10.1159/000530021 · Cited by 23 · see citing works
Artom, M., Czuber‐Dochan, W., Sturt, J. A., & Norton, C. S. (2017) · Trials · doi:10.1186/s13063-017-1926-3 · Cited by 23 · see citing works
Romano, D., Chesterman, S., Fuller-Tyszkiewicz, M., Evans, S., Dober, M., Gearry, R., Gibson, P. R., Knowles, S., McCombie, A., O, E., et al. (2024) · Inflammatory Bowel Diseases · doi:10.1093/ibd/izad122 · Cited by 19 · see citing works
“37,40 This suggests that hybrid designs that include a mixture of self-directed and therapist-led content are important for future work to incorporate in trials going forward.”
BackgroundSelf-citationOnline Mindfulness Intervention for Inflammatory Bowel Disease: Adherence and Efficacy
Forbes, L., & Johnson, S. K. (2022) · Frontiers in Psychology · doi:10.3389/fpsyg.2021.709899 · Cited by 18 · see citing works
Rohde, J. A., Barker, J., & Noar, S. M. (2019) · Translational Behavioral Medicine · doi:10.1093/tbm/ibz166 · Cited by 17 · see citing works
Telemedicine in inflammatory bowel diseases: A new brick in the medicine of the future?
Gravina, A. G., Pellegrino, R., Durante, T., Palladino, G., D'Onofrio, R., Mammone, S., Arboretto, G., Auletta, S., Imperio, G., Ventura, A., et al. (2023) · World Journal of Methodology · doi:10.5662/wjm.v13.i4.194 · Cited by 18 · see citing works
Kheirkhah, F., Faramarzi, M., Shafierizi, S., Chehrazi, M., & Basirat, Z. (2023) · Heliyon · doi:10.1016/j.heliyon.2023.e15760 · Cited by 16 · see citing works
Evans, S., Olive, L., Dober, M., Knowles, S., Fuller-Tyszkiewicz, M., O, E., Gibson, P., Raven, L., Gearry, R., McCombie, A., et al. (2022) · BMJ Open · doi:10.1136/bmjopen-2021-060272 · Cited by 15 · see citing works
Self-citationGasparetto, M., Narula, P., Wong, C., Ashton, J. J., Kammermeier, J., Pierik, M. J., Kopylov, U., & Arebi, N. (2025) · The Lancet Digital Health · doi:10.1016/j.landig.2024.12.007 · Cited by 16 · see citing works
Jordan, C., Hayee, B., & Chalder, T. (2019) · Clinical Psychology & Psychotherapy · doi:10.1002/cpp.2326 · Cited by 14 · see citing works
Wang, C., Sheng, Y., Yu, L., Tian, F., Xue, Y., & Zhai, Q. (2023) · Behavioural Brain Research · doi:10.1016/j.bbr.2023.114653 · Cited by 14 · see citing works
Zhao, E., Yu, Q., Abdoulaye, I. A., Mu, Y., Shi, Y., & Zhu, L. (2020) · General Hospital Psychiatry · doi:10.1016/j.genhosppsych.2020.06.002 · Cited by 13 · see citing works
Is social function a good proxy measure of personality disorder?
Tyrer, P. J., Yang, M., Tyrer, H., & Crawford, M. (2021) · Personality and Mental Health · doi:10.1002/pmh.1513 · Cited by 13 · see citing works
Oddsson, S. J., Gunnarsdottir, T., Jóhannsdóttir, L. G., Ámundadóttir, M. L., Frimannsdottir, A., Molander, P., Ylanne, A. K., Íslind, A. S., Óskarsdóttir, M., & Þorgeirsson, T. (2023) · JMIR Formative Research · doi:10.2196/39331 · Cited by 13 · see citing works
Gold, S. L., Chiew, B. A., Rajagopalan, V., & Lavallee, C. M. (2023) · Journal of the Canadian Association of Gastroenterology · doi:10.1093/jcag/gwad029 · Cited by 11 · see citing works
The IBD-Cope: A New Instrument for Measuring Coping in Inflammatory Bowel Disease Patients
McCombie, A., Swaminathan, A., Mulder, R., Frampton, C., Kortlever, T. L., & Gearry, R. B. (2016) · Journal of Crohn s and Colitis · doi:10.1093/ecco-jcc/jjw028 · Cited by 11 · see citing works
Self-citationCognitive Behavioral Therapy for IBD
Mikocka‐Walus, A. A., Andrews, J. M., & Bampton, P. A. (2016) · Inflammatory Bowel Diseases · doi:10.1097/mib.0000000000000672 · Cited by 11 · see citing works
Self-citationPsychological interventions for treatment of inflammatory bowel disease
Tiles-Sar, N., Neuser, J., de Sordi, D., Baltes, A., Preiß, J., Moser, G., & Timmer, A. (2025) · Cochrane Database of Systematic Reviews · doi:10.1002/14651858.cd006913.pub3 · Cited by 12 · see citing works
Treating anxiety and depression in inflammatory bowel disease: a systematic review
Prendergast, K. L., Gowey, M. A., Barnes, M. J., Keller, C. V., Horne, C., & Young, J. N. (2021) · Psychology and Health · doi:10.1080/08870446.2020.1867135 · Cited by 10 · see citing works
Rohde, J. A., Fisher, E. B., Boynton, M. H., Freelon, D., Frohlich, D. O., Barnes, E. L., & Noar, S. M. (2022) · JMIR Formative Research · doi:10.2196/34960 · Cited by 11 · see citing works
Rada, C., Gheonea, D. I., Ţieranu, C. G., & Popa, D. E. (2022) · Frontiers in Psychology · doi:10.3389/fpsyg.2021.807107 · Cited by 10 · see citing works
Review article: Telecare in gastroenterology—Within the COVID ‐19 pandemic and beyond
Hakak, F., Patel, R. N., & Gearry, R. B. (2024) · Alimentary Pharmacology & Therapeutics · doi:10.1111/apt.17956 · Cited by 9 · see citing works
Self-citationMarchese, S. H., Naftaly, J. P., & Pandolfino, J. (2024) · Translational Gastroenterology and Hepatology · doi:10.21037/tgh-24-10 · Cited by 8 · see citing works
“Though there is more evidence for CBT helping to decrease IBS symptoms, it is possible that CBT could also help with improving IBD symptoms, coping (18,19), health-related QOL [HRQoL; (26,27)], symptoms of depression or anxiety (18,26), catastrophizing (26), and visceral sensitivity (26).”
Matthias, C., Fawson, S., Li, Y., Sweeney, L., Moss-Morris, R. E., & Norton, C. S. (2021) · Gastrointestinal Nursing · doi:10.12968/gasn.2021.19.9.28 · Cited by 8 · see citing works
Naude, C., Skvarc, D., Biurra, Y. C., Blake, L., Evans, S., Knowles, S. R., Eric, O., Prasertsung, C., Russell, L., Bassili, A., et al. (2024) · Journal of Psychosomatic Research · doi:10.1016/j.jpsychores.2024.111984 · Cited by 8 · see citing works
Self-citationGregory, V. L. (2019) · Journal of Evidence-Based Social Work · doi:10.1080/26408066.2019.1610682 · Cited by 7 · see citing works
Watt, M., Peerani, F., Madsen, K. L., Siffledeen, J. S., Kroeker, K. I., Lim, A., Tandon, P., & Hyde, A. M. (2022) · Crohn s & Colitis 360 · doi:10.1093/crocol/otac036 · Cited by 6 · see citing works
Emerson, C., Skvarc, D., Mikocka‐Walus, A. A., OLIVE, L. S., Gibson, P. R., & Fuller‐Tyszkiewicz, M. (2024) · Digestive Diseases and Sciences · doi:10.1007/s10620-024-08468-9 · Cited by 6 · see citing works
Self-citationCorrick, S., Johnson, E., Isley, S., Vandermeer, B., Dolgoy, N. D., Bates, J., Godfrey, E., Soltys, C., Muir, C., Tegg, N. L., et al. (2024) · PLOS mental health. · doi:10.1371/journal.pmen.0000048 · Cited by 5 · see citing works
Hanlon, I., Hewitt, C., Evans, S., Taylor, J., Selinger, C., & Mikocka-Walus, A. (2022) · Journal of Health Psychology · doi:10.1177/1359105320945001 · Cited by 4 · see citing works
“Although this online intervention was useful and well received by patients (McCombie et al., 2016; MikockaWalus et al., 2015), it was not developed for people with co-morbid anxiety and/or depression.”
BackgroundMethodInfluentialSelf-citationGreywoode, R., Philippou, A., Ullman, T., & Keefer, L. (2025) · Inflammatory Bowel Diseases · doi:10.1093/ibd/izaf145 · Cited by 3 · see citing works
Wang, H., Ding, J., Liu, G., Sun, G., Zhang, X., Xiao, W., Cai, Y., & Lin, A. (2025) · Frontiers in Medicine · doi:10.3389/fmed.2025.1630034 · Cited by 2 · see citing works
Zare, F., Ramezankhani, A., Ghaffari, M., & Yarmohammadi, S. (2022) · ranian Journal of Health Education and Health Promotion · doi:10.52547/ijhehp.10.1.93 · Cited by 2 · see citing works
Li, Y. (2022) · Occupational Therapy International · doi:10.1155/2022/6393139 · Cited by 2 · see citing works
RetractedPatricia, F., Lesley A, G., Gia Ly, J., Maia, K., Shelby, A., Dale, D., Teaghan, P., & Charles N, B. (2022) · Journal of Depression and Anxiety Disorders · doi:10.36959/362/481 · Cited by 1 · see citing works
Gastrointestinal Disorders: Inflammatory Bowel Disease and Irritable Bowel Syndrome
Graff, L. A., & Lackner, J. M. (2021) · Comprehensive Clinical Psychology · doi:10.1016/b978-0-12-818697-8.00118-7 · Cited by 1 · see citing works
Internet-Delivered Cognitive Behavioural Therapy for the Management of Chronic Non-Cancer Pain
CADTH (2022) · Canadian Journal of Health Technologies · doi:10.51731/cjht.2022.462 · Cited by 1 · see citing works
Jones, A. S. K., Seaton, N., Harding, S., Duff, A., Hudson, J. L., Wroe, A. L., Norton, S., Singh, H., Onih, J., & Moss-Morris, R. E. (2025) · Inflammatory Bowel Diseases · doi:10.1093/ibd/izaf259 · Cited by 2 · see citing works
Uran, B. N. Ö., Yüksel, E. S., Avdal, E. Ü., & Arkan, B. (2019) · Akademik Gastroenteroloji Dergisi · doi:10.17941/agd.532735 · Cited by 1 · see citing works
Häuser, W. (2020) · Springer eBooks · doi:10.1007/978-3-662-59104-8_36 · Cited by 1 · see citing works
Marmara, S. M., & Kemer, G. (2023) · Journal of Counseling & Development · doi:10.1002/jcad.12499 · Cited by 1 · see citing works
Hunt, M. G., Tse, C. S., Suh, L. H. K., Yang, E., Bui, C., Davis, A., Siddiqi, R., & Tian, V. (2025) · Behaviour Research and Therapy · doi:10.1016/j.brat.2025.104702 · Cited by 1 · see citing works
Wileman, V., Czuber‐Dochan, W., Moss-Morris, R. E., Dibley, L., McGuinness, S., Miller, L., Norton, C. S., & Taylor, S. J. (2026) · PLoS ONE · doi:10.1371/journal.pone.0350560 · Cited by 1 · see citing works
Zhao, Y.-Y., Zhang, L., Yang, Y.-X., Hao, N., Wang, B., & Liu, Y. (2021) · World Chinese Journal of Digestology · doi:10.11569/wcjd.v29.i12.628 · Cited by 1 · see citing works
Jackson, B. D. (2019) · Minerva Access (University of Melbourne) · Cited by 1 · see citing works
Investigación clínica en 2016: artículos destacados
Trejo, G., Marqués, A. M., Hernández, S. V., & Boscá-Watts, M. M. (2017) · Enfermedad Inflamatoria Intestinal al Día · doi:10.1016/j.eii.2017.03.002
Gracie, D. J. (2018) · White Rose eTheses Online (University of Leeds, The University of Sheffield, University of York)
Pang, L., Liu, H., Liu, Z., Tan, J.-Y. B., Zhou, L., Qiu, Y., Lin, X., He, J., Li, X., Lin, S., et al. (2021) · doi:10.2196/preprints.28978
Elzaki, A. A., Elnour, H., Elhaj, M., Kajoak, S. A., & Alzain, A. F. H. (2022) · Pakistan Journal of Medical and Health Sciences · doi:10.53350/pjmhs221651242
Lampert-Okin, S. L., Howe, M. M., Feldman, E. C. H., Gumidyala, A. P., & Greenley, R. N. (2023) · Children s Health Care · doi:10.1080/02739615.2023.2226394
Contrasting Psychotherapeutic Treatments in Inflammatory Bowel Disease: an Exploratory Review
Zerpa, C. E. (2024) · Revista Costarricense de Psicología · doi:10.22544/rcps.v43i01.06
Su, J., Zou, L., Wang, J., Wang, W., Lu, Y., Li, J., Kang, J., Tang, Z., Yin, A., Ren, H., et al. (2025) · SSRN Electronic Journal · doi:10.2139/ssrn.5137569
(2025) · Elsevier eBooks · doi:10.1016/b978-3-437-21835-4.00116-5
IBD-specific Cognitive Behavioral Therapy: Sustainability of effect after three years
Evertsz, F. B., Goes, F. L. S., Stokkers, P. C. F., Sanderman, R., Verdam, M. G. E., Sprangers, M. A. G., & Bockting, C. (2025) · Clinical Psychology in Europe · doi:10.32872/cpe.14717
Norton, C. S., Syred, J., Kerry, S., Artom, M., Sweeney, L., Hart, A., Czuber‐Dochan, W., Taylor, S. J., Mihaylova, B., Roukas, C., et al. (2021) · Figshare · doi:10.6084/m9.figshare.15103024
Norton, C. S., Syred, J., Kerry, S., Artom, M., Sweeney, L., Hart, A., Czuber‐Dochan, W., Taylor, S. J., Mihaylova, B., Roukas, C., et al. (2021) · Figshare · doi:10.6084/m9.figshare.15103027
Norton, C. S., Syred, J., Kerry, S., Artom, M., Sweeney, L., Hart, A., Czuber‐Dochan, W., Taylor, S. J., Mihaylova, B., Roukas, C., et al. (2021) · Figshare · doi:10.6084/m9.figshare.15103033
Norton, C. S., Syred, J., Kerry, S., Artom, M., Sweeney, L., Hart, A., Czuber‐Dochan, W., Taylor, S. J. C., Mihaylova, B., Roukas, C., et al. (2021) · Figshare · doi:10.6084/m9.figshare.15103021
Sweeney, L., Moss-Morris, R. E., Czuber‐Dochan, W., & Norton, C. S. (2021) · Figshare · doi:10.6084/m9.figshare.14443203
Norton, C. S., Syred, J., Kerry, S., Artom, M., Sweeney, L., Hart, A., Czuber‐Dochan, W., Taylor, S. J. C., Mihaylova, B., Roukas, C., et al. (2021) · Figshare · doi:10.6084/m9.figshare.15103030
Qi-wen, F., Jiang, Y.-L., Ge, X.-Y., & Yang, J.-H. (2026) · World Journal of Psychiatry · doi:10.5498/wjp.119197
- Authors
- McCombie, A., Gearry, R., Andrews, J., Mulder, R., & Mikocka-Walus, A.
- Affiliations
- University of South Australia (AU)
- University of Otago (NZ)
- Corresponding author
- McCombie, Andrew
- Venue
- Inflammatory Bowel Diseases
- Publisher
- Oxford University Press (OUP)
- Published
- 2016-01
- Volume
- 22
- Issue
- 1
- Pages
- 171-181
- ISSN
- 1078-0998 (ISSN-L)
- OpenAlex
- W2317616155
- Cited by
- 100
- References
- 57
- Citations by year
- 2026: 2 · 2025: 10 · 2024: 7 · 2023: 11 · 2022: 11 · 2021: 18 · 2020: 9 · 2019: 7 · 2018: 7 · 2017: 11 · 2016: 7
- FWCI
- 13.39
- Type
- journal article
- Language
- en
- Open access
- bronze
- doi.org
- Locations
- Inflammatory Bowel Diseases (publishedVersion)
- PubMed (publishedVersion)
- White Rose Research Online (University of Leeds, The University of Sheffield, University of York) (submittedVersion)
- Adelaide Research & Scholarship (AR&S) (University of Adelaide) (submittedVersion)
- Funders
- University of Otago
- Topics
- Social Sciences › Psychology › Applied Psychology › Digital Mental Health Interventions
- Life Sciences › Biochemistry, Genetics and Molecular Biology › Genetics › Inflammatory Bowel Disease
- Social Sciences › Psychology › Experimental and Cognitive Psychology › Anxiety, Depression, Psychometrics, Treatment, Cognitive Processes
- Keywords
- computerized cognitive behavioral therapy, inflammatory bowel disease
- MeSH terms
- Adult, Major Depressive Disorder, Female, Follow-Up Studies, Humans, Male, Prognosis, Quality of Life, Therapy, Computer-Assisted, Inflammatory Bowel Diseases, Cognitive Behavioral Therapy
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review
