Is Alzheimer’s a disease of the white matter?

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Hypothetical model of dynamic biomarkers of the Alzheimer's pathological cascade

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Soluble protein oligomers in neurodegeneration: lessons from the Alzheimer's amyloid β-peptide

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Alzheimer's Disease Is a Synaptic Failure

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Diffusion tensor imaging: Concepts and applications

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Diffusion tensor MR imaging of the human brain

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Silent Brain Infarcts and the Risk of Dementia and Cognitive Decline

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Tau Suppression in a Neurodegenerative Mouse Model Improves Memory Function

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Reducing Endogenous Tau Ameliorates Amyloid ß-Induced Deficits in an Alzheimer's Disease Mouse Model

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Dendritic Function of Tau Mediates Amyloid-β Toxicity in Alzheimer's Disease Mouse Models

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Formation of Neurofibrillary Tangles in P301L Tau Transgenic Mice Induced by Aβ42 Fibrils

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Axonopathy and Transport Deficits Early in the Pathogenesis of Alzheimer’s Disease

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A white matter disorder in dementia of the Alzheimer type: A pathoanatomical study

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Cerebral white matter lesions, vascular risk factors, and cognitive function in a population‐based study

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Amyloid deposition precedes tangle formation in a triple transgenic model of Alzheimer's disease

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The many faces of tau

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Tau blocks traffic of organelles, neurofilaments, and APP vesicles in neurons and enhances oxidative stress

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Silent Brain Infarcts and White Matter Lesions Increase Stroke Risk in the General Population

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Overexpression of tau protein inhibits kinesin-dependent trafficking of vesicles, mitochondria, and endoplasmic reticulum: Implications for Alzheimer’s disease

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Review: Cerebral microvascular pathology in ageing and neurodegeneration

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Role of abnormally phosphorylated tau in the breakdown of microtubules in Alzheimer disease.

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Evolution of the neuropathology of Alzheimer's disease

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Cerebral Amyloid Angiopathy

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Amyloid-β/Fyn–Induced Synaptic, Network, and Cognitive Impairments Depend on Tau Levels in Multiple Mouse Models of Alzheimer's Disease

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Hyaluronan accumulates in demyelinated lesions and inhibits oligodendrocyte progenitor maturation

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White Matter Lesions in an Unselected Cohort of the Elderly: Molecular Pathology Suggests Origin From Chronic Hypoperfusion Injury

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Diffusion tensor imaging of cingulum fibers in mild cognitive impairment and Alzheimer disease

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Cerebral White Matter Lesions and the Risk of Dementia

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Tau Reduction Prevents Aβ-Induced Defects in Axonal Transport

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Microtubule-binding drugs offset tau sequestration by stabilizing microtubules and reversing fast axonal transport deficits in a tauopathy model

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Expression pattern of the transcription factor Olig2 in response to brain injuries: implications for neuronal repair.

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Absolute diffusivities define the landscape of white matter degeneration in Alzheimer’s disease

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Axon pathology in neurological disease: a neglected therapeutic target

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Temporal Profile of Amyloid-β (Aβ) Oligomerization in an in Vivo Model of Alzheimer Disease

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Relationships between hippocampal atrophy, white matter disruption, and gray matter hypometabolism in Alzheimer's disease

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Heterogeneous age-related breakdown of white matter structural integrity: Implications for cortical “disconnection” in aging and Alzheimer's disease.

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Hyaluronan blocks oligodendrocyte progenitor maturation and remyelination through TLR2

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Cognitive correlates of ventricular enlargement and cerebral white matter lesions on magnetic resonance imaging. The Rotterdam Study.

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Arrested oligodendrocyte lineage maturation in chronic perinatal white matter injury

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White matter lesions on magnetic resonance imaging in clinically diagnosed Alzheimer’s disease. Evidence for heterogeneity

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Regional white matter volume differences in nondemented aging and Alzheimer's disease

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Decreased white matter integrity in late-myelinating fiber pathways in Alzheimer's disease supports retrogenesis

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White matter damage in Alzheimer disease and its relationship to gray matter atrophy

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Amyloid-β peptide induces oligodendrocyte death by activating the neutral sphingomyelinase–ceramide pathway

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Increased Aβ Peptides and Reduced Cholesterol and Myelin Proteins Characterize White Matter Degeneration in Alzheimer's Disease

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White matter pathology isolates the hippocampal formation in Alzheimer's disease

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Cortical and Leptomeningeal Cerebrovascular Amyloid and White Matter Pathology in Alzheimer’s Disease

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Multiple DTI index analysis in normal aging, amnestic MCI and AD. Relationship with neuropsychological performance

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Triple‐transgenic Alzheimer's disease mice exhibit region‐specific abnormalities in brain myelination patterns prior to appearance of amyloid and tau pathology

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Leukoencephalopathy in diffuse hemorrhagic cerebral amyloid angiopathy

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Quantification of myelin loss in frontal lobe white matter in vascular dementia, Alzheimer’s disease, and dementia with Lewy bodies

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Magnetic Resonance Imaging White Matter Hyperintensities and Brain Volume in the Prediction of Mild Cognitive Impairment and Dementia

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Early Oligodendrocyte/Myelin Pathology in Alzheimer's Disease Mice Constitutes a Novel Therapeutic Target

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Amyloid-β Peptides Are Cytotoxic to Oligodendrocytes

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Quantitation of cerebral atrophy in preclinical and end-stage Alzheimer’s disease

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Dynamic changes in myelin aberrations and oligodendrocyte generation in chronic amyloidosis in mice and men

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White matter lesions in an unselected cohort of the elderly: astrocytic, microglial and oligodendrocyte precursor cell responses

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Neuropathology of white matter changes in Alzheimer’s disease and vascular dementia

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Posterior cingulate cortex atrophy and regional cingulum disruption in mild cognitive impairment and Alzheimer’s disease

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Axonal Transport RatesIn VivoAre Unaffected by Tau Deletion or Overexpression in Mice

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Focal demyelination in Alzheimer’s disease and transgenic mouse models

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Measuring progression of cerebral white matter lesions on MRI

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Functions and malfunctions of the tau proteins

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Diffusion tensor imaging detects age-dependent white matter changes in a transgenic mouse model with amyloid deposition

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Voxel-based assessment of gray and white matter volumes in Alzheimer's disease

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The APOE ɛ4 allele modulates brain white matter integrity in healthy adults

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Cerebral Amyloid Angiopathy: Accumulation of Aβ in Interstitial Fluid Drainage Pathways in Alzheimer's Disease

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In vivo axonal transport rates decrease in a mouse model of Alzheimer's disease

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Microglial activation in white matter lesions and nonlesional white matter of ageing brains

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White matter changes in dementia of Alzheimer's type: the difference in vulnerability between cell compartments

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Loss of tau elicits axonal degeneration in a mouse model of Alzheimer's disease

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Comparison of the pathology of cerebral white matter with post‐mortem magnetic resonance imaging (MRI) in the elderly brain

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Sub-regional hippocampal injury is associated with fornix degeneration in Alzheimer’s disease.

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Axonopathy in an APP/PS1 transgenic mouse model of Alzheimer’s disease

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Age-dependent axonal degeneration in an Alzheimer mouse model

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Microstructural white matter changes in cognitively normal individuals at risk of amnestic MCI

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Abnormalities of the uncinate fasciculus and posterior cingulate fasciculus in mild cognitive impairment and early Alzheimer's disease: A diffusion tensor tractography study

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Alterations in multiple measures of white matter integrity in normal women at high risk for Alzheimer's disease

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White matter lesions defined by diffusion tensor imaging in older adults

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Stroke and Vascular Cognitive Impairment

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White matter imaging changes in subjective and mild cognitive impairment

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